2022 , 令和3年度 信州大学医学部学術奨励賞（2回） 2021 , ノバルティス・リウマチ医学賞 2021 , 日本骨代謝学会学術賞 2020 , Albert Nelson Marquis Lifetime Achievement Award 2019 , Albert Nelson Marquis Lifetime Achievement Award 2019 , The Tohoku Journal of Experimental Medicine. TOP 30 Papers Downloaded in 2018（第6位） #Downloads:2294 times, Time Cited:2 2019 , Top 10% most cited PLOS ONE papers published in 2017 2018 , 信州大学医学部整形外科同門会賞 2018 , Albert Nelson Marquis Lifetime Achievement Award 2017 , Albert Nelson Marquis Lifetime Achievement Award 2016 , 日本骨粗鬆症学会研究奨励賞 2015 , 第33回日本骨代謝学会ポスター口演賞 2014 , 平成25年度信州大学医学部学術奨励賞 2014 , 第23回遺伝医学セミナー最高得点受賞 2013 , 平成24年度信州大学医学部学術奨励賞 2013 , 第44回日本結合組織学会優秀演題賞 2012 , 平成23年度信州大学医学部学術奨励賞 2012 , ASBMR/John Haddad Young Investigator Award. 2011 , 第117回中部日本整形外科災害外科学会奨励賞 2011 , ASBMR/Young Investigator Travel Grant 2009 , 第22回日本軟骨代謝学会賞 2008 , ASBMR/Harold M. Frost Young Investigator Award 2008 , DePuy Spine Research Award, Pediatric Orthopaedic Society of North America 2007 , Travel award: Gordon Research Conference; Cartilage Biology & Pathology 2006 , Keystone Symposia on Molecular and Cellular Biology Award
研究職歴等
研究職歴 2006- , Harvard Medical School Assistant Professor
論文 Verification of efficacy and safety of ibandronate or denosumab for postmenopausal osteoporosis after 12-month treatment with romosozumab as sequential therapy: The prospective VICTOR study. BONNE,162:116480 2022 Author: Kobayakawa T, Miyazaki A, Takahashi J, Nakamura Y*.
Comparable efficacy of denosumab and romosozumab in patients with rheumatoid arthritis receiving glucocorticoid administration. Mod Rheumatol.,:roac014. 2022 Author: Kobayakawa T, Miyazaki A, Kanayama Y, Hirano Y, Takahashi J, Suzuki T, Nakamura Y*.
Effects of romosozumab with and without active vitamin D analog supplementation for postmenopausal osteoporosis. Clin Nutr ESPEN,48:267-274 2022 Author:Kobayakawa T, Miyazaki A, Takahashi J, Nakamura Y*.
Peficitinib improves bone fragility by recovering bone turnover imbalance in arthritic mice. J Pharmacol Sci.,148:134-141 2022 Author: Sugawara S, Hanaoka K, Emori T, Takeshita N, Fujii Y, Nakano M, Suzuki T, Takahashi J, Nakamura Y*.
Efficacy of romosozumab for osteoporosis in a patient with osteogenesis imperfecta: A case report. Mod Rheumatol Case Rep.,6:128-133 2022 Author:Uehara M, Nakamura Y*, Nakano M, Miyazaki A, Suzuki T, Takahashi J.
Efficacy of denosumab therapy for a 12-year-old woman with Williams syndrome with osteoporosis and history of fractures: A case report. J Med Case Rep,15:594 2021 Author:Uehara M, Nakamura Y*, Suzuki T, Nakano M, Takahashi J.
Efficacy and Safety of Oral Ibandronate versus Intravenous Zoledronic Acid on Bone Metabolism and Bone Mineral Density in Postmenopausal Japanese Women with Osteoporosis. J Clin Med,10:5420 2021 Author:Uehara M, Nakamura Y*, Suzuki T, Nakano M, Takahashi J.
Associations of LRP5 and MTHFR Gene Variants with Osteoarthritis Prevalence in Elderly Women: A Japanese Cohort Survey Randomly Sampled from a Basic Resident Registry. Ther Clin Risk Manag.,17:1065-1073 2021 Author:Nakano M, Yui H, Kikugawa S, Tokida R, Sakai N, Kondo N, Endo N, Haro H, Shimodaira H, Suzuki T, Kato H, Takahashi J, Nakamura Y*.
MTHFR gene C677T polymorphism predicts progression of spinal osteoarthritis. J Clin Endocrinol Metab.,:dgab591. 2021 Author:Nakano M, Nakamura Y*, Urano T, Miyazaki A, Suzuki T, Watanabe K, Takahashi J, Shiraki M
Short- to Mid-Term Clinical Outcomes of Posterior-Stabilized Cementless Total Knee Arthroplasty with Trabecular Metal Components. Ther Clin Risk Manag. ,17:809-816 2021 Author:Momose T, Nakamura Y*, Nakano M, Maeda T, Morioka S, Sobajima A, Nakatsuchi Y, Takahashi J, Nawata M
Denosumab versus romosozumab for postmenopausal osteoporosis treatment. Sci Rep,11:11801 2021 Author:Kobayakawa T, Miyazaki A, Saito M, Suzuki T, Takahashi J, Nakamura Y*
Zinc Pharmacotherapy for Elderly Osteoporotic Patients with Zinc Deficiency in a Clinical Setting Nutrients,13:1814 2021 Author:Nakano M, Nakamura Y*,Miyazaki A, Takahashi J
Real-world effects and adverse events of romosozumab in Japanese osteoporotic patients: A prospective cohort study. Bone Rep,14:101068 2021 Author:Kobayakawa T, Suzuki T, Nakano M, Saito M, Miyazaki A, Takahashi J, Nakamura Y*
Reference values for bone metabolism in a Japanese cohort survey randomly sampled from a basic elderly resident registry. Sci Rep,11:7822 2021 Author:Tokida R, Uehara M, Nakano M, Suzuki T, Sakai N, Ikegami S, Takahashi J, Nakamura Y, Kato H
Pentosidine and carboxymethyl-lysine associate differently with prevalent osteoporotic vertebral fracture and various bone markers Sci Rep,10:22090 2020 Author:Nakano M, Nakamura Y*, Suzuki T, Miyazaki A, Takahashi J, Saito M, Shiraki M
Implications of historical height loss for prevalent vertebral fracture, spinal osteoarthritis, and gastroesophageal reflux disease Sci Rep,10:19036 2020 Author:Nakano M, Nakamura Y*, Suzuki T, Kobayashi T, Takahashi J, Shiraki M
Same-side insufficiency fractures of the tibia and femur after denosumab discontinuation: A case report Mod Rheumatol Case Rep,5:178-181 2020 Author:Koiwai H, Kamimura M, Nakamura Y*, Takahashi J, Taguchi A
Spinal osteoarthritis is associated with stature loss independently of incident vertebral fracture in postmenopausal women. Spine (Phila Pa 1976) ,45:E1400-E1404 2020 Author:Nakano M, Nakamura Y*, Suzuki T, Takahashi J, Shiraki M
Differences in bone mineral density and bone turnover markers between subjects with and without diffuse idiopathic skeletal hyperostosis. Spine (Phila Pa 1976),45:E1677-E1681 2020 Author:Uehara M, Takahashi J, Ikegami S, Tokida R, Nishimura H, Sakai N, Nakamura Y, Kato H
The first experience of denosmab therapy on patients with Ehlers-Danlos syndrome and osteoporosis: Detailed observation of two patients. Mod Rheumatol Case Rep,:44210 2020 Author:Yasukawa S, Uehara M, Suzuki T, Nakano M, Kosho T, Nakamura Y*, Takahashi J
Remarkable loss of bone mineral density in 6 months after denosumab discontinuation: a case report Mod Rheumatol Case Rep,4:218-221 2020 Author:Maezumi Y, Kamimura M, Nakamura Y*, Takahashi J
Efficacy of denosumab therapy after alendronate treatment for a 66-year-old woman with Camurati-Engelmann disease and osteoporosis: A case report Mod Rheumatol Case Rep,4:131-134 2020 Author:Uehara M, Nakamura Y*, Suzuki T, Takahashi J, Kato H
ZMAT2, a newly-identified potential disease-causing gene in congenital radioulnar synostosis, modulates BMP signaling Bone,136:115349 2020 Author:Suzuki T, Nakano M, Komatsu M, Takahashi J, Kato H, Nakamura Y*
Two adipocytokines, leptin and adiponectin, independently predict osteoporotic fracture risk at different bone sites in postmenopausal women Bone,137:115404 2020 Author:Nakamura Y*, Nakano M, Suzuki T, Sato J, Kato H, Takahashi J, Shiraki M
Efficacy of 4-year denosumab treatment alone or in combination with teriparatide in Japanese postmenopausal osteoporotic women Mod Rheumatol,29:676-681 2019 Author:Suzuki T, Nakamura Y*, Kato H
Efficacy of denosumab therapy for osteoporosis-pseudoglioma syndrome with osteoporosis: A case report Mod Rheumatol Case Rep,3:45-48 2019 Author:Miyazawa S, Nakamura Y*, Suzuki T, Kato H
The Shisa3 knockout mouse exhibits normal bone phenotype J Bone Miner Metab,37:967-975 2019 Author:Murakami K, Zhifeng H, Suzuki T, Kobayashi Y, Nakamura Y*
Additive effects of eldecalcitol in poorly responding long-term bisphosphonate treatment for osteoporosis Osteoporos Sarcopenia,5:57-61 2019 Author:Kamimura M, Ikegami S, Mukaiyama K, Koiwai H, Nakamura Y*, Taguchi A, Kato H
Effects of monthly minodronate with or without eldecalcitol addition in osteoporosis patients with rheumatoid arthritis: An 18-month prospective study Osteoporos Sarcopenia,5:122-127 2019 Author:Suzuki T, Nakamura Y*, Kato H
Unexpected rapid increase in bone mineral density by bisphosphonate therapy after multiple spinal fractures: A case report J Med Case Rep,13:288 2019 Author:Koiwai H, Kamimura M, Takahashi J, Nakamura Y*, Kato H
Efficacy of denosumab therapy for a 21-year-old woman with Prader-Willi syndrome, osteoporosis and history of fractures: a case report Ther Clin Risk Manag,15:303-307 2019 Author:Uehara M, Nakamura Y*, Takahashi J, Suzuki T, Iijima M, Arakawa Y, Ida K, Kosho T, Kato H
Calcium and vitamin D supplementation with 3-year denosumab treatment is beneficial to enhance bone mineral density in postmenopausal patients with osteoporosis and rheumatoid arthritis Ther Clin Risk Manag,15:15-22 2018 Author:Suzuki T, Nakamura Y*, Kato H
Efficacy of teriparatide and denosumab combination treatment in a patient with atypical femoral fracture and Behçet's disease: A case report and review of the literature Mod Rheumatol Case Rep,2:92-96 2018 Author:Uehara M, Nakamura Y*, Takahashi J, Isobe F, Ikegami S, Suzuki T, Uchiyama S, Kamimura M, Kato H
Novel method for evaluation of hindfoot alignment in weight-bearing position using laser beam J Phys Ther Sci,30:474-478 2018 Author:Ohnishi T, Hida M, Nakamura Y*, Wada C
Denosumab significantly improves lumbar spine bone mineral density more in treatment-naïve than in long-term bisphosphonate-treated patients Bone Rep,8:110-114 2018 Author:Suzuki T, Nakamura Y*, Kamimura M, Kato H
Efficacy of denosumab for glucocorticoid-induced osteoporosis in an adolescent patient with Duchenne muscular dystrophy. A case report JBJS Case Connect,8:e22 2018 Author:Kumaki D, Nakamura Y*, Sakai N, Kosho T, Nakamura A, Hirabayashi S, Suzuki T, Kamimura M, Kato H
Determination of serum bone-related minerals during denosumab treatment in osteoporosis patients with rheumatoid arthritis Clin Nutr ESPEN,26:53-56 2018 Author:Suzuki T, Nakamura Y*, Kato H
Efficacy, safety, and compliance of ibandronate treatment for 3 years in postmenopausal Japanese women with primary osteoporosis Osteoporos Sarcopenia,4:69-72 2018 Author:Suzuki T, Nakamura Y*, Kato H
Efficacy of denosumab therapy for neurofibromatosis type I with osteoporosis and history of fractures: a case report Ther Clin Risk Manag,14:1243-1246 2018 Author:Uehara M, Nakamura Y*, Takahashi J, Kamimura M, Isobe F, Yamaguchi T, Kosho T, Uchiyama S, Suzuki T, Kato H
Suppression of methotrexate-induced elevations in the serum alanine aminotransferase level of patients with rheumatoid arthritis who had prior hepatitis B infection Health,10:531-541 2018 Author:Noguchi O, Nakamura Y, Kato H
Tofacitinib Versus Non-Tumor Necrosis Factor Biologics for Patients With Active Rheumatoid Arthritis Arch Rheumatol,33(2):154-159 2018 Author:Nakamura Y*, Suzuki T, Yamazaki H, Kato H
Olfactomedin-like protein OLFML1 inhibits Hippo signaling and mineralization in osteoblasts Biochem Biophys Res Commun,505(2):419-425 2018 Author:Murakami K, Kikugawa S, Kobayashi Y, Uehara S, Suzuki T, Kato H, Udagawa N, Nakamura Y*
Efficacy and Safety of Denosumab Therapy for Osteogenesis Imperfecta Patients with Osteoporosis-Case Series J Clin Med,7:E479 2018 Author:Kobayashi T, Nakamura Y*, Suzuki T, Yamaguchi T, Takeda R, Takagi M, Hasegawa T, Kosho T, Kato H
Comparison of the effects of denosumab with either active vitamin D or native vitamin D on bone mineral density and bone turnover markers in postmenopausal osteoporosis Mod Rheumatol,28(2):376-379 2018 Author:Suzuki T, Nakamura Y*, Tanaka M, Kamimura M, Ikegami S, Uchiyama S, Kato H
Effects of denosumab on bone metabolism and bone mineral density with anti-TNF inhibitors, tocilizumab, or abatacept in osteoporosis with rheumatoid arthritis Ther Clin Risk Manag,14:453-459 2018 Author:Suzuki T, Nakamura Y*, Kato H
Significant improvement of bone mineral density by denosumab treatment in Japanese osteoporotic patients following breast cancer treatment Ther Clin Risk Manag,14:543-549 2018 Author:Nakamura Y*, Kamimura M, Morikawa A, Taguchi A, Suzuki T, Kato H
Pretreatment of daily teriparatide enhances the increase of bone mineral density in cortical bones by denosumab therapy Ther Clin Risk Manag,14:637-642 2018 Author:Kamimura M, Taguchi A, Nakamura Y*, Koiwai H, Ikegami S, Uchiyama S, Kato H
Efficacy of denosumab in two cases with multiple-system atrophy and osteoporosis Ther Clin Risk Manag,14:817-822 2018 Author:Uehara M, Nakamura Y*, Takahashi J, Suzuki T, Kato H
Adequate nutrition status important for bone mineral density improvement in a patient with anorexia nervosa Ther Clin Risk Manag,14:945-948 2018 Author:Nakamura Y*, Kamimura M, Koiwai H, Kato H
Vitamin D and Calcium Addition during Denosumab Therapy over a Period of Four Years Significantly Improves Lumbar Bone Mineral Density in Japanese Osteoporosis Patients Nutrients,10(3):E272 2018 Author:Suzuki T, Nakamura Y*, Kato H
Efficacy of Denosumab for Osteoporosis in Two Patients with Adult-Onset Still's Disease-Denosumab Efficacy in Osteoporotic Still's Disease Patients J Clin Med,7(4):E63 2018 Author:Kumaki D, Nakamura Y*, Suzuki T, Kato H
Significant improvement of bone mineral density by denosumab without bisphosphonate pre-treatment in glucocorticoid-induced osteoporosis. Mod Rheumatol,28:885-889 2018 Author:Suzuki T, Nakamura Y*, Kato H
Effects of denosumab on osteoporosis in three cases with anorexia nervosa and a review of the literature. Mod Rheumatol Case Rep,2:104-106 2018 Author:Isobe F, Nakamura Y*, Suzuki T, Kato H
Significant improvement of bone mineral density and bone turnover markers by denosumab therapy in bisphosphonate-unresponsive patients Osteoporos Int,28:559-566 2017 Author:Kamimura M, Nakamura Y*, Ikegami S, Uchiyama S, Kato H, Taguchi A
Painful locking of the wrist in a patient with pseudoachondroplasia confirmed by COMP mutation J Surg Case Rep,2017:rjw216 2017 Author:Ideta H, Uchiyama S, Hayashi M, Kosho T, Nakamura Y, Kato H
Comparison of effectiveness and safety of ibandronate and minodronate combined with eldecalcitol in primary osteoporosis of women: A 1-year follow-up study Osteoporos Sarcopenia,3:37-44 2017 Author:Tanaka M, Nakamura Y*, Itoh S, Kato Y
Compliance and discontinuation of denosumab treatment in postmenopausal Japanese women with primary osteoporosis or rheumatoid arthritis and osteoporosis Osteoporos Sarcopenia,3:108-111 2017 Author:Suzuki T, Nakamura Y*, Kamimura M, Ikegami S, Uchiyama S, Kato H
Serum bone alkaline phosphatase is a useful marker to evaluate lumbar bone mineral density in Japanese postmenopausal osteoporotic women during denosumab treatment Ther Clin Risk Manag,13:1343-1348 2017 Author:Nakamura Y*, Suzuki T, Kato H
A Jak1/2 inhibitor, baricitinib, inhibits osteoclastogenesis by suppressing RANKL expression in osteoblasts in vitro PLoS One,12(7):e0181126 2017 Author:Murakami K, Kobayashi Y, Uehara S, Suzuki T, Koide M, Yamashita T, Nakamura M, Takahashi N, Kato H, Udagawa N, Nakamura Y*
Changes of Bone-Related Minerals during Denosumab Administration in Post-Menopausal Osteoporotic Patients Nutrients,9(8):E871 2017 Author:Suzuki T, Nakamura Y*, Kato H
Denosumab significantly improves bone mineral density with or without bisphosphonate pre-treatment in osteoporosis with rheumatoid arthritis Denosumab improves bone mineral density in osteoporosis with rheumatoid arthritis Arch Osteoporos,12:80 2017 Author:Nakamura Y*, Suzuki T, Kato H
Vitamin D and calcium are required at the time of denosumab administration during osteoporosis treatment Bone Res,5:17021 2017 Author:Nakamura Y*, Suzuki T, Kamimura M, Ikegami S, Mukaiyama K, Uchiyama S, Taguchi A, Kato H
Bony findings detected by MRI may reflect the pathophysiology of osteoarthritis with thumb carpometacarpal joint pain Int J Rheum Dis,20:1950-1957 2017 Author:Komatsu M, Kamimura M, Nakamura Y*, Mukaiyama K, Ikegami S, Hayashi M, Uchiyama S, Kato H
Increased serum 25(OH)D3 levels in post-menopausal Japanese women with osteoporosis after 3-year bisphosphonate treatment Tohoku J Exp Med,242:241-246 2017 Author:Nakamura Y*, Uchiyama S, Kamimura M, Ikegami S, Komatsu M, Kato H Keywords:bisphosphonates; fracture; native vitamin D; osteoporosis; post-menopausal women;
Efficacy of denosumab for osteoporosis in three female patients with osteogenesis imperfecta Tohoku J Exp Med,242:115-120 2017 Author:Uehara M, Nakamura Y*, Takahashi J, Kamimura M, Ikegami S, Suzuki T, Uchiyama S, Yamaguchi T, Kosho T, Kato H Keywords:bone mineral density; bone turnover marker; denosumab; fracture; osteogenesis imperfecta;
Goniothalamin induces mitochondria-mediated apoptosis associated with endoplasmic reticulum stress-induced activation of JNK in HeLa cells Oncol Lett,13:119-128 2017 Author:Sophonnithiprasert T, Mahabusarakam W, Nakamura Y, Watanapokasin R
Short-term bisphosphonate treatment reduces serum 25(OH) vitamin D3 and alters values of parathyroid hormone, pentosidine, and bone metabolic markers Ther Clin Risk Manag,13:161-168 2017 Author:Kamimura M, Uchiyama S, Nakamura Y*, Ikegami S, Mukaiyama K, Kato H
Alfacalcidol Increases the Therapeutic Efficacy of Ibandronate on Bone Mineral Density in Japanese Women with Primary Osteoporosis Tohoku J Exp Med,241(4):319-326 2017 Author:Nakamura Y*, Suzuki T, Kamimura M, Ikegami S, Uchiyama S, Kato H
Vitamin D and Calcium Are Required during Denosumab Treatment in Osteoporosis with Rheumatoid Arthritis Nutrients,9(5):E428 2017 Author:Nakamura Y*, Suzuki T, Yoshida T, Yamazaki H, Kato H
Two-year clinical outcome of denosumab treatment alone and in combination with teriparatide in Japanese treatment-naive postmenopausal osteoporotic women Bone Res,5:16055 2017 Author:Nakamura Y*, Suzuki T, Kamimura M, Ikegami S, Mukaiyama K, Uchiyama S, Taguchi A, Kato H
Value changes in bone turnover markers and bone mineral density using ibandronate in Japanese postmenopausal osteoporotic patients J Nutr Disord Ther,6:188 2016 Author:Nakamura Y*, Ikegami S, Takanashi Y, Kamimura M, Uchiyama S, Kato H
Effects of denosumab treatment during early pregnancy - A case report J Nutr Disord Ther,6:189 2016 Author:Isobe F, Nakamura Y*, Kamimura M, Uchiyama S, Kato H
Monthly minodronate inhibits bone resorption to a greater extent than does monthly risedronate Osteoporos Sarcopenia,2:170-174 2016 Author:Kamimura M, Nakamura Y*, Ikegami S, Komatsu M, Uchiyama S, Kato H
Association of self-reported height loss and kyphosis with loss of teeth in Japanese elderly Oral Health Dent Manag,15:69-74 2016 Author:Taguchi A, Kamimura M, Sugino N, Uchida K, Kitamura Y, Ikegami S, Nakamura Y, Uchiyama S, Kato H
原発性骨粗鬆症に対する12カ月間のイバンドロネート注射製剤とエルデカルシトール併用治療の有効性と安全性の検討 日本骨粗鬆症学会雑誌 = The journal of Japan Osteoporosis Society,2(3):275-283 2016 Author:田中 瑞栄; 中村 幸男; 伊藤 聰一郎; 島本 周治; 加藤 義治; Keywords:骨粗鬆症; イバンドロネート; エルデカルシトール; 併用療法; osteoporosis; ibandronate; eldecalcitol; coadministration;
Risk factors of adjacent vertebral collapse after percutaneous vertebroplasty for osteoporotic vertebral fracture in postmenopausal women BMC Musculoskelet Disord,17:12 2016 Author:Takahara K, Kamimura M, Moriya H, Ashizawa R, Koike T, Hidai Y, Ikegami S, Nakamura Y*, Kato H
Bone alterations are associated with ankle osteoarthritis joint pain Sci Rep,6:18717 2016 Author:Nakamura Y*, Uchiyama S, Kamimura M, Komatsu M, Ikegami S, Kato H
Bisphosphonate pre-treatment diminishes the therapeutic benefits teriparatide in Japanese osteoporotic patients Tohoku J Exp Med,239:17-24 2016 Author:Kamimura M, Nakamura Y*, Ikegami S, Uchiyama S, Kato H
The dynamin inhibitor dynasore inhibits bone resorption by rapidly disrupting actin rings of osteoclasts J Bone Miner Metab,34:395-405 2016 Author:Thirukonda GJ, Uehara S, Nakayama T, Yamashita T, Nakamura Y, Mizoguchi T, Takahashi N, Yagami K, Udagawa N, Kobayashi Y
Clinical implications of hip flexion in the measurement of spinal bone mineral density J Clin Densitom,19:270-276 2016 Author:Ikegami S, Kamimura M, Uchiyama S, Nakamura Y, Mukaiyama K, Kato H
Associations of self-reported height loss and kyphosis with vertebral fractures in Japanese women 60 years and older: a cross-sectional survey Sci Rep,6:29199 2016 Author:Kamimura M, Nakamura Y, Sugino N, Uchiyama S, Komatsu M, Ikegami S, Kato H, Taguchi A
Delayed wound healing after tooth extraction and self-reported kyphosis in Japanese men and women Sci Rep,6:36309 2016 Author:Taguchi A, Kamimura M, Nakamura Y*, Sugino N, Ichinose A, Maezumi H, Fukuzawa K, Ashizawa R, Takahara K, Gushiken S, Mukaiyama K, Ikegami S, Uchiyama S, Kato H
Bone alterations in painful osteoarthritic shoulder J Case Rep,5:84-87 2015 Author:Komatsu M, Nakamura Y*, Kamimura M, Ikegami S, Mukaiyama K, Uchiyama S, Kato H
Goniothalamin enhances TRAIL-induced apoptosis in colorectal cancer cells through DR5 upregulation and cFLIP downregulation Int J Oncol,47:2188-2196 2015 Author:Sophonnithiprasert T, Nilwarangkoon S, Nakamura Y, Watanapokasin R
Antiproliferation and apoptosis induction in colorectal cancer cells by goniothalamin J Med Assoc Thai,98(Suppl9):S146-151 2015 Author:Sophonnithiprasert T, Mahabusarakam W, Nakamura Y, Watanapokasin R
Changes in serum vitamin D and PTH values using denosumab with or without bisphosphonate pre-treatment in osteoporotic patients: A short-term study BMC Endocr Disord,15:81 2015 Author:Nakamura Y*, Kamimura M, Ikegami S, Mukaiyama K, Uchiyama S, Taguchi A, Kato H
Eldecalcitol, in combination with bisphosphonate, is effective for treatment of Japanese osteoporotic patients Tohoku J Exp Med,237:339-343 2015 Author:Mukaiyama K, Uchiyama S, Nakamura Y, Ikegami S, Taguchi A, Kamimura M, Kato H
A case series of pregnancy- and lactation- associated osteoporosis and a review of the literature Ther Clin Risk Manag,11:1361-1365 2015 Author:Nakamura Y*, Kamimura M, Ikegami S, Mukaiyama K, Komatsu M, Uchiyama S, Kato H
Wnt16 regulates osteoclast differentiation in conjunction with Wnt5a Biochem Biophys Res Commun,463:1278-1283 2015 Author:Kobayashi Y, Thirukonda GJ, Nakamura Y, Koide M, Yamashita T, Uehara S, Kato H, Udagawa N, Takahashi N
Expression profiles of human CCN genes in patients with osteoarthritis or rheumatoid arthritis J Orthop Sci,20:708-716 2015 Author:Komatsu M, Nakamura Y*, Maruyama M, Abe K, Watanapokasin R, Kato H
PCSK5 mutation in a patient with the VACTERL association BMC Res Notes,8:228 2015 Author:Nakamura Y*, Kikugawa S, Seki S, Takahata M, Iwasaki N, Terai H, Matsubara M, Fujioka F, Inagaki H, Kobayashi T, Kimura T, Kurahashi H, Kato H
Osteoarthritis in the forefoot accompanied with joint pain is potentially associated with bone alterations Int J Diagn Imaging,2:64-69 2015 Author:Nakamura Y*, Kamimura M, Uchiyama S, Komatsu M, Ikegami S, Kato H
The skeletal muscle cross sectional area in long-term bisphosphonate users is smaller than that of bone mineral density-matched controls with increased serum pentosidine concentrations Bone,75:84-87 2015 Author:Uchiyama S, Ikegami S, Kamimura M, Mukaiyama K, Nakamura Y, Nonaka K, Kato H
Elevation of serum alkaline phosphatase (ALP) level in postmenopausal women is caused by high bone turnover Aging Clin Exp Res,27:413-418 2015 Author:Mukaiyama K, Kamimura M, Uchiyama S, Ikegami S, Nakamura Y, Kato H
Factors that characterize bone health with aging in healthy postmenopausal women J Bone Miner Metab,33:440-447 2015 Author:Ikegami S, Uchiyama S, Nakamura Y, Mukaiyama K, Hirabayashi H, Kamimura M, Nonaka K, Kato H
Serum pentosidine levels after 3 years of bisphosphonate treatment in post-menopausal osteoporotic women Endocr Res,40:172-176 2015 Author:Hashidate H, Kamimura M, Ikegami S, Mukaiyama K, Uchiyama S, Nakamura Y*, Kato H
Knee joint pain potentially due to bone alterations in a knee osteoarthritis patient Am J Case Rep,15:534-537 2014 Author:Komatsu M, Nakamura Y*, Kamimura M, Uchiyama S, Mukaiyama K, Ikegami S, Kato H
Rapid bone destruction in a patient with knee osteoarthritis -A case report and review of the literature- Clin Cases Miner Bone Metab,11:239-242 2014 Author:Komatsu M, Kamimura M, Nakamura Y*, Mukaiyama K, Ikegami S, Uchiyama S, Kato H
Temporal and Spatial Expression Patterns of Bone Morphogenetic Protein 3 in Developing Zebrafish Open Rheumatol J,8:69-72 2014 Author:Ito-Amano M, Nakamura Y*, Morisaki M, He X, Hayashi M, Watanapokasin R, Kato H
The Pathophysiology and Progression of Hip Osteoarthritis Accompanied with Joint Pain are Potentially Due to Bone Alterations - Follow-up Study of Hip OA Patients Open Rheumatol J,8:46-53 2014 Author:Kamimura M, Nakamura Y*, Uchiyama S, Ikegami S, Mukaiyama K, Kato H
Case with Atypical Clinical Course Diagnosed as Osteoarthritis, Osteonecrosis, Subchondral Insufficiency Fracture, or Rapidly Destructive Coxopathy Open Rheumatol J,8:20-23 2014 Author:Nakamura Y*, Kamimura M, Mukaiyama K, Ikegami S, Uchiyama S, Kato H
Changes in Bone Turnover Markers and Fracture in Osteo¬porosis: A Review of the Literature Ann Orthop Rheumatol,2:1023 2014 Author:Nakamura Y*, Kamimura M, Ikegami S, Mukaiyama K, Uchiyama S, Kato H
Tramadol/acetaminophen causes constipation more frequently in women with degenerative spinal disorders than in those with degenerative joint disorders Drugs Ther Perspect,30:149-154 2014 Author:Kamimura M, Nakamura Y*, Ikegami S, Ichinose A, Uchiyama S, Kato H
Significant differences of brain blood flow in patients with chronic low back pain and acute low back pain detected by brain SPECT JOURNAL OF ORTHOPAEDIC SCIENCE,19(3):384-389 2014 Author:Nakamura Y, Nojiri K, Yoshihara H, Takahata T, Honda-Takahashi K, Kubo S, Sakatsume K, Kato H, Maruta T, Honda T
The Pathophysiology of Primary Hip Osteoarthritis may Originate from Bone Alterations Open Rheumatol J,7:112-118 2013 Author:Kamimura M, Nakamura Y*, Ikegami S, Mukaiyama K, Uchiyama S, Kato H
Joint pain undergoes a transition in accordance with signal changes of bones detected by MRI in hip osteoarthritis Open Rheumatol J,7:67-74 2013 Author:Kamimura M, Nakamura Y*, Uchiyama S, Ikegami S, Kato H
let-7 and miR-140 microRNAs coordinately regulate skeletal development Proc Natl Acad Sci U S A,110:E3291-3300 2013 Author:Papaioannou G, Inloes J, Nakamura Y, Paltrinieri E, Kobayashi T
Apoptotic Induction of Skin Cancer Cell Death by Plant Extracts J Med Assoc Thai,96(Suppl 1):S60-64 2013 Author:Thuncharoen W, Chulasiri M, Nilwarangkoon S, Nakamura Y, Watanapokasin R
Sox9 is upstream of microRNA-140 in cartilage Appl Biochem Biotechnol,166:64-71 2012 Author:Nakamura Y, He X, Kato H, Wakitani S, Kobayashi T, Watanabe S, Iida A, Tahara H, Warman ML, Watanapokasin R, Postlethwait JH
Identification and functional analysis of Zranb2 as a novel Smad-binding protein that suppresses BMP signaling J Cell Biochem,113:808-814 2012 Author:Ohte S, Kokabu S, Iemura SI, Sasanuma H, Yoneyama K, Shin M, Suzuki S, Fukuda T, Nakamura Y, Jimi E, Natsume T, Katagiri T
Histone deacetylase-4 is required during early cranial neural crest development for generation of the zebrafish palatal skeleton BMC Dev Biol,12:16 2012 Author:Delaurier A, Nakamura Y, Braasch I, Khanna V, Kato H, Wakitani S, Postlethwait JH, Kimmel CB
Craniofacial abnormalities result from knock down of nonsyndromic clefting gene, crispld2, in zebrafish Genesis,50:871-881 2012 Author:Yan Q, Chiquet BT, DeVault L, Warman ML, Nakamura Y, Swindell EC, Hecht JT
進行性偽性リウマチ様異形成の原因遺伝子であるWISP3の役割解明に向けた動物モデルアプローチ 日本小児整形外科学会雑誌,20:1-5 2011 Author:中村幸男、脇谷滋之、田原秀晃、加藤博之、Matthew L. Warman
Wwp2 is essential for palatogenesis mediated by the interaction between Sox9 and mediator subunit 25 Nat Commun,2:251 2011 Author:Nakamura Y, Yamamoto K, He X, Otsuki B, Kim Y, Murao H, Soeda T, Tsumaki N, Deng JM, Zhang Z, Behringer RR, Crombrugghe BD, Postlethwait JH, Warman ML, Nakamura T, Akiyama H
α-Mangostin induces apoptosis in human chondrosarcoma cells through downregulation of ERK/JNK and Akt signaling pathway J Agric Food Chem,59:5746-5754 2011 Author:Krajarng A, Nakamura Y, Suksamrarn S, Watanapokasin R
Effects of α-mangostin on apoptosis induction of human colon cancer World J Gastroenterol,17:2086-2095 2011 Author:Watanapokasin R, Jarinthanan F, Nakamura Y, Sawasjirakij N, Jaratrungtawee A, Suksamrarn S
Chondrocyte-specific microRNA-140 regulates endochondral bone development and targets Dnpep to modulate bone morphogenetic protein signaling Mol Cell Biol,31:3019-3028 2011 Author:Nakamura Y, Inloes J, Katagiri T, Kobayashi T
Zebrafish models for human FKRP muscular dystrophies Hum Mol Genet,19:623-633 2010 Author:Kawahara G, Guyon JR, Nakamura Y, Kunkel LM
Potential of xanthones from tropical fruit mangosteen as anti-cancer agents: Caspase-dependent apoptosis induction in vitro and in mice Appl Biochem Biotechnol,162:1080-1094 2010 Author:Watanapokasin R, Jarinthanan F, Jerusalmi A, Suksamrarn S, Nakamura Y, Sukseree S, Uthaisang-Tanethpongtamb W, Ratananukul P, Sano T
Temporal and spatial expression of CCN genes in zebrafish Dev Dyn,239:1755-1767 2010 Author:Fernando CA, Conrad PA, Bartels CF, Marques T, To M, Balow SA, Nakamura Y*, Warman ML
Normal growth and development in mice over-expressing the CCN family member WISP3 J Cell Commun Signal,3:105-113 2009 Author:Nakamura Y*, Cui Y, Fernando C, Kutz WE, Warman ML
Wif-1 is expressed at cartilage-mesenchyme interfaces and impedes Wnt3a-mediated inhibition of chondrogenesis J Cell Sci,122:3627-3637 2009 Author:Surmann-Schmitt C, Widmann N, Dietz U, Saeger B, Eitzinger N, Nakamura Y, Rattel M, Latham R, Hartmann C, von der Mark H, Schett G, von der Mark K, Stock M
Unique roles of microRNA140 and its host gene WWP2 in cartilage biology J Musculoskelet Neuronal Interact,8:321-322 2008 Author:Nakamura Y, He X, Kobayashi T, Yan YL, Postlethwait JH, Warman ML
The CCN family member Wisp3, mutant in progressive pseudo rheumatoid dysplasia, modulates BMP and Wnt signaling J Clin Invest,117:3075-3086 2007 Author:Nakamura Y, Weidinger G, Liang JO, Aquilina-Beck A, Tamai K, Moon RT, Warman ML
Coordinate expression of BMP-2, BMP receptors and Noggin in normal mouse spine J Clin Neurosci,13:250-256 2006 Author:Nakamura Y, Nakaya H, Saito N, Wakitani S
Use of bone morphogenetic protein 2 and diffusion chambers to engineer cartilage tissue for the repair of defects in articular cartilage Arthritis Rheum,52:155-163 2005 Author:Nawata M, Wakitani S, Nakaya H, Tanigami A, Seki T, Nakamura Y, Saito N, Sano K, Hidaka E, Takaoka K
Meningioma arising in Werner syndrome confirmed by mutation analysis J Clin Neurosci,12:503-506 2005 Author:Nakamura Y*, Shimizu T, Ohigashi Y, Itou N, Ishikawa Y
Expression profiles and functional analyses of Wnt-related genes in human joint disorders Am J Pathol,167:97-105 2005 Author:Nakamura Y, Nawata M, Wakitani S
Microbubble-enhanced ultrasound exposure promotes uptake of methotrexate into synovial cells and enhanced antiinflammatory effects in the knees of rabbits with antigen-induced arthritis Arthritis Rheum,52:2559-2566 2005 Author:Nakaya H, Shimizu T, Isobe K, Tensho K, Okabe T, Nakamura Y, Nawata M, Yoshikawa H, Takaoka K, Wakitani S
The effects of heat on the biological activity of recombinant human bone morphogenetic protein-2 J Bone Miner Metab,23:420-425 2005 Author:Ohta H, Wakitani S, Tensho K, Horiuchi H, Wakabayashi S, Saito N, Nakamura Y, Nozaki K, Imai Y, Takaoka K
Expression profiles of BMP-related molecules induced by BMP-2 or -4 in muscle-derived primary culture cells J Bone Miner Metab,23:426-434 2005 Author:Nakamura Y, Wakitani S, Saito N, Takaoka K
Embryonic stem cells form articular cartilage, not teratomas, in osteochondral defects of rat joints Cell Transplant,13:331-336 2004 Author:Wakitani S, Aoki H, Harada Y, Sonobe M, Morita Y, Mu Y, Tomita N, Nakamura Y, Takeda S, Watanabe TK, Tanigami A
Autologous bone marrow stromal cell transplantation for repair of full-thickness articular cartilage defects in human patellae: Two case reports Cell Transplant,13:595-600 2004 Author:Wakitani S, Mitsuoka T, Nakamura N, Toritsuka Y, Nakamura Y, Horibe S
Multiple periarticular osteosclerosis accompanied by joint destruction treated with bilateral total knee arthroplasty J Arthroplasty,18:100-104 2003 Author:Nakamura Y*, Nomura T, Nakajima S, Ito N, Wakitani S
Triple primary sarcoma in Werner syndrome with a novel mutation Rheumatology,42:1-2 2003 Author:Nakamura Y*, Shimizu T, Ishikawa Y, Matsumoto T, Sugimoto M, Goto M, Yoshimura Y, Wakitani S, Takaoka K
Temporal and spatial expression profiles of BMP receptors and Noggin during BMP-2 induced ectopic bone formation J Bone Miner Res,18:1854-1862 2003 Author:Nakamura Y, Wakitani S, Nakayama J, Wakabayashi S, Horiuchi H, Takaoka K
Longitudinal median nerve conduction studies after endoscopic carpal tunnel release Hand Surg,4:145-149 1999 Author:Nakamura Y, Uchiyama S, Toriumi H, Nakagawa H, Miyasaka T
Spinal osteoarthritis is associated with stature loss independently of incident vertebral fracture in postmenopausal women Spine (Phila Pa 1976) Author:Nakano M, Nakamura Y*, Suzuki T, Takahashi J, Shiraki M
Compliance, Adverse Effects, Bone-related Mineral and Vitamin D Status, and Literature Review of Denosumab Therapy for Osteoporosis in Japan ASBMR 2018 Annual Meeting in MO, Canada 2018 Presenter:Nakamura Y, Suzuki T, Kato H
Identification and Molecular Analysis of a Potential Disease-Causing Mutation in ZMAT2 in Congenital Radioulnar Synostosis ASBMR 2018 Annual Meeting in MO, Canada 2018 Presenter:Suzuki T, Nakamura Y, Kobayashi T, Kato H
Identification of a novel PCSK5 frameshift mutation in a patient with the VACTERL association ASBMR 2014 Annual Meeting, Houston, TX, USA 2014 Presenter:Nakamura Y, Kikugawa S, Seki S, Takahata M, Iwasaki N, Terai H, Matsubara M, Fujioka F, Inagaki H, Kobayashi T, Kimura T, Kurahashi H, Kato H
The roles of miR-140 and Wwp2 in skeletal development AIMM/ASBMR John Haddad Young Investigators' Meeting. Snowmass, CO, USA 2012 Presenter:Nakamura Y
The roles of microRNA140 during endochondral bone development 5th Medical Biotech Forum. Beijing, China 2011 Presenter:Nakamura Y
Model organism approaches to understand the role of WISP3, the gene that is mutated in Progressive Pseudorheumatoid Dysplasia A Seminar at Endocrine Division. Massachusetts General Hospital. Boston, MA, USA 2008 Presenter:Nakamura Y
Model organism approaches to understand the role of WISP3, the gene that is mutated in Progressive Pseudorheumatoid Dysplasia A Seminar at Department of Orthopaedic Surgery. University of California. Davis, CA, USA 2008 Presenter:Nakamura Y
Deciphering the roles of Wisp3 in cartilage using model organism approaches A Seminar at Matsumoto Dental University. Nagano, Japan 2008 Presenter:Nakamura Y
The role of microRNA140 during cartilage development Sun Valley Workshop on Skeletal Tissue Biology. Sun Valley, ID, USA 2008 Presenter:Nakamura Y
Wnt-1 inducible signaling protein 3 (WISP3) can modulate BMP and Wnt signaling Gordon Research Conference. Cartilage Biology & Pathology. Ventura, CA, USA 2007 Presenter:Nakamura Y
Using zebrafish to identify biologic activities for WISP3, the gene that is mutated in Progressive Pseudorheumatoid Dysplasia RA Interface Rounds. Brigham & Women's Hospital. Boston, MA, USA 2007 Presenter:Nakamura Y
Zebrafish studies of cartilage biology 21st Annual David Grice Lecture. Children's Hospital Boston. Boston, MA, USA 2007 Presenter:Nakamura Y
Model organism approaches toward identifying the role of Wisp3 in cartilage 19th Annual Meeting of the Japanese Society of Cartilage Metabolism. Yokohama, Japan 2006 Presenter:Warman ML, Nakamura Y
Deciphering the function of Wnt1-inducible signaling protein 3 (WISP3) in cartilage Developmental Biology in Orthopaedics. American Academy of Orthopaedic Surgeons 2006. Research Symposium. Toronto, Canada 2006 Presenter:Warman ML, Nakamura Y
Temporal and spatial expression profiles of BMP receptors and Noggin during BMP-2 induced ectopic bone formation 1st Joint Meeting of International Bone and Mineral Society-Japanese Society for Bone and Mineral Research. Osaka, Japan 2003 Presenter:Nakamura Y, Wakitani S, Nakayama J, Wakabayashi S, Horiuchi H, Takaoka K
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