論文 Anti-nucleolin aptamer, iSN04, inhibits the inflammatory responses in C2C12 myoblasts by modulating the β-catenin/NF-κB signaling pathway. Biochem Biophys Res Commun,664:1-8 2023 Author:Yamamoto M, Miyoshi M, Morioka K, Mitani T, Takaya T*.
Myogenetic oligodeoxynucleotides as anti-nucleolin aptamers inhibit the growth of embryonal rhabdomyosarcoma cells. Biomedicines,10(11):2691 2022 Author:Nohira N, Shinji S, Nakamura S, Nihashi Y, Shimosato T, Takaya T*.
Myogenetic oligodeoxynucleotide restores differentiation and reverses inflammation of myoblasts aggravated by cancer-conditioned medium. Muscles,1(2):111-120 2022 Author:Nihashi Y, Yamamoto M, Shimosato T, Takaya T*.
Identification of a novel osteogenetic oligodeoxynucleotide (osteoDN) that promotes osteoblast differentiation in a TLR9-independent manner. Nanomaterials,12(10):1680 2022 Author:Nihashi Y, Miyoshi M, Umezawa K, Shimosato T, Takaya T*.
Three-dimensional structural analysis of mitochondria composing each subtype of fast-twitch muscle fibers in chicken. J Vet Med Sci,84(6):809-816 2022 Author:Makida S, Kametani K, Hosotani M, Takahashi N, Iwasaki T, Hasegawa Y, Takaya T, Ueda H, Watanabe T.
ロコモ創薬シーズとしての筋・骨形成型オリゴDNA. Medical Science Digest,48(5):244-245 2022 Author:高谷智英*.
Myogenetic oligodeoxynucleotide complexed with berberine promotes differentiation of chicken myoblasts. Anim Sci J,92(1):e13597 2021 Author:Nihashi Y, Shinji S, Umezawa K, Shimosato T, Ono T, Kagami H, Takaya T*.
Myogenetic oligodeoxynucleotide (myoDN) recovers the differentiation of skeletal muscle myoblasts deteriorated by diabetes mellitus. Front Physiol,12:679152 2021 Author:Nakamura S, Yonekura S, Shimosato T, Takaya T*.
Transcription of endogenous retrovirus group K members and their neighboring genes in chicken skeletal muscle myoblasts. J Poult Sci,58(2):79-87 2021 Author:Takaya T*, Nihashi Y, Ono T, Kagami H.
Identification of the myogenetic oligodeoxynucleotides (myoDNs) that promote differentiation of skeletal muscle myoblasts by targeting nucleolin. Front Cell Dev Biol,8:616706 2021 Author:Shinji S, Umezawa K, Nihashi Y, Nakamura S, Shimosato T, Takaya T*.
Physiological and pathological mitochondrial clearance is related to pectoralis major muscle pathogenesis in broilers with wooden breast syndrome. Front Physiol,11:579 2020 Author:Hosotani M, Kawasaki T, Hasegawa Y, Wakasa Y, Hoshino M, Takahashi N, Ueda H, Takaya T, Iwasaki T, Watanabe T.
Berberine and palmatine inhibit the growth of human rhabdomyosarcoma cells. Biosci Biotechnol Biochem,84(1):63-75 2020 Author:Shinji S, Nakamura S, Nihashi Y, Umezawa K, Takaya T*.
Distinct cell proliferation, myogenic differentiation, and gene expression in skeletal muscle myoblasts of layer and broiler chickens. Sci Rep,9:16527 2019 Author:Nihashi Y, Umezawa K, Shinji S, Hamaguchi Y, Kobayashi H, Kono T, Ono T, Kagami H, Takaya T*.
Toll-like receptor ligand-dependent inflammatory responses in chick skeletal muscle myoblasts. Dev Comp Immunol,91:115-122 2019 Author:Nihashi Y, Ono T, Kagami H, Takaya T*.
Theophylline suppresses interleukin-6 expression by inhibiting glucocorticoid receptor signaling in pre-adipocytes. Arch Biochem Biophys,646:98-106 2018 Author:Mitani T, Takaya T, Harada N, Katayama S, Yamaji R, Nakamura S, Ashida H.
Autonomous xenogenic cell fusion of murine and chick skeletal muscle myoblasts. Anim Sci J,88(11):1880-1885 2017 Author:Takaya T*, Nihashi Y, Kojima S, Ono T, Kagami H.
Lectin-like oxidized low-density lipoprotein receptor-1 plays an important role in vascular inflammation in current smokers. J Atheroscler Thromb,20(6):585-590 2013 Author:Takanabe-Mori R, Ono K, Wada H, Takaya T, Ura S, Yamakage H, Satoh-Asahara N, Shimatsu A, Takahashi Y, Fujita M, Fujita Y, Sawamura T, Hasegawa K.
Roles of microRNAs and myocardial cell differentiation. Prog Mol Biol Transl Sci,111:139-152 2012 Author:Takaya T, Nishi H, Horie T, Ono K, Hasegawa K.
Highly purified eicosapentaenoic acid increases interleukin-10 levels of peripheral blood monocytes in obese patients with dyslipidemia. Diabetes Care,35(12):2631-2639 2012 Author:Satoh-Asahara N, Shimatsu A, Sasaki Y, Nakaoka H, Himeno A, Tochiya M, Kono S, Takaya T, Ono K, Wada H, Suganami T, Hasegawa K, Ogawa Y.
Distinct characteristics of circulating vascular endothelial growth factor-A and C levels in human subjects. PLoS One,6(12):e29351 2011 Author:Wada H, Ura S, Kitaoka S, Satoh-Asahara N, Horie T, Ono K, Takaya T, Takanabe-Mori R, Akao M, Abe M, Morimoto T, Murayama T, Yokode M, Fujita M, Shimatsu A, Hasegawa K.
The discovery of LOX-1, its ligands and clinical significance. Cardiovasc Drugs Ther,25(5):379-391 2011 Author:Yoshimoto R, Fujita Y, Kakino A, Iwamoto S, Takaya T, Sawamura T.
A natural p300-specific histone acetyltransferase inhibitor, curcumin, in addition to angiotensin-converting enzyme inhibitor, exerts beneficial effects on left ventricular systolic function after myocardial infarction in rats. Circ J,75(9):2151-2159 2011 Author:Sunagawa Y, Morimoto T, Wada H, Takaya T, Katanasaka Y, Kawamura T, Yanagi S, Marui A, Sakata R, Shimatsu A, Kimura T, Kakeya H, Fujita M, Hasegawa K.
MicroRNA-27a regulates beta cardiac myosin heavy chain gene expression by targeting thyroid hormone receptor beta1 in neonatal rat ventricular myocytes. Mol Cell Biol,31(4):744-755 2011 Author:Nishi H, Ono K, Horie T, Nagao K, Kinoshita M, Kuwabara Y, Watanabe S, Takaya T, Tamaki Y, Takanabe-Mori R, Wada H, Hasegawa K, Iwanaga Y, Kawamura T, Kita T, Kimura T.
Cyclin-dependent kinase 9 forms a complex with GATA4 and is involved in the differentiation of mouse ES cells into cardiomyocytes. J Cell Physiol,226(1):248-254 2011 Author:Kaichi S, Takaya T, Morimoto T, Sunagawa Y, Kawamura T, Ono K, Shimatsu A, Baba S, Heike T, Nakahata T, Hasegawa K.
Lectin-like oxidized low-density lipoprotein receptor-1 is required for the adipose tissue expression of proinflammatory cytokines in high-fat diet-induced obese mice. Biochem Biophys Res Commun,398(3):576-580 2010 Author:Takanabe-Mori R, Ono K, Sowa N, Wada H, Takaya T, Horie T, Satoh-Asahara N, Shimatsu A, Fujita M, Sawamura T, Hasegawa K.
Cell line-dependent differentiation of induced pluripotent stem cells into cardiomyocytes in mice. Cardiovasc Res,88(2):314-323 2010 Author:Kaichi S, Hasegawa K, Takaya T, Yokoo N, Mima T, Kawamura T, Morimoto T, Ono K, Baba S, Doi H, Yamanaka S, Nakahata T, Heike T.
Left ventricular expression of lectin-like oxidized low-density lipoprotein receptor-1 in failing rat hearts. Circ J,74(4):723-729 2010 Author:Takaya T, Wada H, Morimoto T, Sunagawa Y, Kawamura T, Takanabe-Mori R, Shimatsu A, Fujita Y, Sato Y, Fujita M, Kimura T, Sawamura T, Hasegawa K.
Cyclin-dependent kinase-9 is a component of the p300/GATA4 complex required for phenylephrine-induced hypertrophy in cardiomyocytes. J Biol Chem,285(13):9556-9568 2010 Author:Sunagawa Y, Morimoto T, Takaya T, Kaichi S, Wada H, Kawamura T, Fujita M, Shimatsu A, Kita T, Hasegawa K.
Aldosterone signaling associates with p300/GATA4 transcriptional pathway during the hypertrophic response of cardiomyocytes. Circ J,74(1):156-162 2010 Author:Yoshida Y, Morimoto T, Takaya T, Kawamura T, Sunagawa Y, Wada H, Fujita M, Shimatsu A, Kita T, Hasegawa K.
MicroRNA-1 and microRNA-133 in spontaneous myocardial differentiation of mouse embryonic stem cells. Circ J,73(8):1492-1497 2009 Author:Takaya T, Ono K, Kawamura T, Takanabe R, Kaichi S, Morimoto T, Wada H, Kita T, Shimatsu A, Hasegawa K.
Up-regulated expression of microRNA-143 in association with obesity in adipose tissue of mice fed high-fat diet. Biochem Biophys Res Commun,376(4):728-732 2008 Author:Takanabe R, Ono K, Abe Y, Takaya T, Horie T, Wada H, Kita T, Satoh N, Shimatsu A, Hasegawa K.
Myocardial regulation of p300 and p53 by doxorubicin involves ubiquitin pathways. Circ J,72(9):1506-1511 2008 Author:Morimoto T, Fujita M, Kawamura T, Sunagawa Y, Takaya T, Wada H, Shimatsu A, Kita T, Hasegawa K.
Statins activate GATA-6 and induce differentiated vascular smooth muscle cells. Biochem Biophys Res Commun,374(4):731-736 2008 Author:Wada H, Abe M, Ono K, Morimoto T, Kawamura T, Takaya T, Satoh N, Fujita M, Kita T, Shimatsu A, Hasegawa K.
The dietary compound curcumin inhibits p300 histone acetyltransferase activity and prevents heart failure in rats. J Clin Invest,118(3):868-878 2008 Author:Morimoto T, Sunagawa Y, Kawamura T, Takaya T, Wada H, Nagasawa A, Komeda M, Fujita M, Shimatsu A, Kita T, Hasegawa K.
Identification of p300-targeted acetylated residues in GATA4 during hypertrophic responses in cardiac myocytes. J Biol Chem,283(15):9828-9835 2008 Author:Takaya T, Kawamura T, Morimoto T, Ono K, Kita T, Shimatsu A, Hasegawa K.
Spaceflight results in increase of thick filament but not thin filament proteins in the paramyosin mutant of Caenorhabditis elegans. Adv Space Res,41(5):816-823 2008 Author:Adachi R, Takaya T, Kuriyama K, Higashibata A, Ishioka N, Kagawa H.
Trichostatin A induces myocardial differentiation of monkey ES cells. Biochem Biophys Res Commun,356(2):386-391 2007 Author:Hosseinkhani M, Hasegawa K, Ono K, Kawamura T, Takaya T, Morimoto T, Wada H, Shimatsu A, Prat SG, Suemori H, Nakatsuji N, Kita T.
C. elegans model for studying tropomyosin and troponin regulations of muscle contraction and animal behavior. Adv Exp Med Biol,592:153-161 2007 Author:Kagawa H, Takaya T, Ruksana R, Anokye-Danso F, Amin MZ, Terami H.
Tissue expression of four troponin I genes and their molecular interactions with two troponin C isoforms in Caenorhabditis elegans. Genes Cells,10(3):261-276 2005 Author:Ruksana R, Kuroda K, Terami H, Bando T, Kitaoka S, Takaya T, Sakube Y, Kagawa H.
Possible chicken meat production by ex-ovo embryo culture system and the application for poultry biotechnology. The 68th International Congress of Meat Science and Technology 2022(Aug. 24) Presenter:Shindo H, Saito S, Takizawa S, Murai K, Takaya T, Hiramatsu K, Kawahara T, Kagami H.
Application of a novel chick embryo culture system for developmental studies and chicken meat production. The 68th International Congress of Meat Science and Technology 2022(Aug. 24) Presenter:Murai K, Takizawa S, Saito S, Shindo H, Takaya T, Hiramatsu K, Kawahara T, Kagami H.
Stem cell application for chimera generation and the molecular identification in chickens. 日本畜産学会第129回大会 2021(Sep. 15) Presenter:Kagami H, Sato S, Kaneko K, Hiramatsu K, Takaya T, Sheng G.
Discovery and application of myogenetic oligodeoxynucleotides (myoDNs). International Joint Seminar 2019 Sejong University-Shinshu University-Kasetsart University 2019(Sep. 24) Presenter:Takaya T.
Action mechanism of myogenetic oligodeoxynucleotides (myoDNs). International Joint Seminar 2019 Sejong University-Shinshu University-Kasetsart University 2019(Sep. 24) Presenter:Shinji S, Takaya T.
Expression of helix-loop-helix transcription factor Ascl4 induces myogenic program in embryonic stem cells. Frontiers in Myogenesis Meeting 2019(Sep. 24) Presenter:Asakura A, Kodaka Y, Watanabe S, Ito H, Verma M, Takaya T, Asakura Y, Kyba M.
筋形成型オリゴ DNA はがん分泌因子による筋分化阻害を回復する. 第21回応用薬理シンポジウム 2019(Sep. 20) Presenter:二橋佑磨, 進士彩華, 下里剛士, 高谷智英.
Application of myogenetic oligodeoxynucleotide to diabetic skeletal muscle myoblasts. 日本核酸医薬学会第5回年会 2019(Jul. 11) Presenter:Nakamura S, Umezawa K, Yonekura S, Shimosato T, Takaya T.
Induction of cardiac differentiation of pluripotent stem cells by myogenetic oligodeoxynucleotide. 日本核酸医薬学会第5回年会 2019(Jul. 10) Presenter:Ishioka M, Nihashi Y, Umezawa K, Kagami H, Shimosato T, Takaya T.
Conformational difference between two types of biologically active oligodeoxynucleotides. 日本核酸医薬学会第5回年会 2019(Jul. 10) Presenter:Umezawa K, Yamamoto Y, Shimosato T, Takaya T.
RNA sequencing for global gene expression associated with proliferation and differentiation in chicken skeletal muscle myoblasts. The 2nd International Conference on Tropical Animal Science and Production 2019(Jul. 10) Presenter:Nihashi Y, Umezawa K, Hamaguchi Y, Kobayashi H, Kono T, Ono T, Kagami H, Takaya T.
Myogenic differentiation-inducing oligodeoxynucleotide recovers the myoblast differentiation impaired by abnormal glucose concentration. The 4th International Conference on Pharma-Food 2018(Nov. 15) Presenter:Nakamura S, Yonekura S, Shimosato T, Takaya T.
Toll-like receptor ligand-dependent inflammatory responses in chick skeletal muscle myoblasts. 2018 International Symposium on Animal Science and Technology 2018(Aug. 10) Presenter:Nihashi Y, Ono T, Kagami H, Takaya T.
Functional structure analyses of the DNA-alkaloid complex promoting myogenic differentiation. 2018 International Symposium on Animal Science and Technology 2018(Aug. 10) Presenter:Shinji S, Umezawa K, Shimosato T, Takaya T.
Myogenic oligodeoxynucleotide, myoDN, induces myocardial differentiation of murine iPS cells. 2018 International Symposium on Animal Science and Technology 2018(Aug. 10) Presenter:Ishioka M, Nihashi Y, Kagami H, Shimosato T, Takaya T.
Intermittent glucose stimulation impairs proliferation and differentiation of C2C12 myoblasts. 2018 International Symposium on Animal Science and Technology 2018(Aug. 10) Presenter:Nakamura S, Yonekura S, Takaya T.
Developmental analysis of the donor mice ES cells in the recipient chick embryo. 2018 International Symposium on Animal Science and Technology 2018(Aug. 10) Presenter:Asai M, Kusudo T, Kobayashi K, Watanabe K, Ono T, Takaya T, Tomioka I, Kagami H.
Comprehensive gene expression analyses between broiler and layer chick skeletal muscle myoblasts. 2018 International Symposium on Animal Science and Technology 2018(Aug. 09) Presenter:Takaya T.
Distinct expression of TLR genes between broiler and layer chick skeletal muscle myoblasts. The 11th Asian Pacific Poulty Conference 2018(Mar. 26) Presenter:Nihashi Y, Ono T, Kagami H, Takaya T.
Novel DNA aptamer activating skeletal muscle stem cells. Symposium on Advanced Materials and 3D Printing for Biomedical Applications 2017(Oct. 20) Presenter:Takaya T.
Regulation of skeletal muscle stem cells for meat production. Japan-Thailand International Symposium on Animal Biotechnology 2017(Jul. 05) Presenter:Takaya T.
Autonomous xenogenic cell fusion of murine and chick skeletal muscle myoblasts. Japan-Thailand International Symposium on Animal Biotechnology 2017(Jul. 05) Presenter:Takaya T, Nihashi Y, Kojima S, Ono T, Kagami H.
Distinct cell characteristics between broiler and layer chick skeletal muscle myoblasts. Japan-Thailand International Symposium on Animal Biotechnology 2017(Jul. 05) Presenter:Nihashi Y, Ono T, Kagami H, Takaya T.
Application of the oligodeoxynucleotide from lactic acid bacteria that promotes myogenic differentiation. Japan-Thailand International Symposium on Animal Biotechnology 2017(Jul. 05) Presenter:Shinji S, Nihashi Y, Umezawa K, Shimosato T, Takaya T.
Efficient production of chicks by ex ovo culture system with novel avian assisted reproductive technology (AART). Japan-Thailand International Symposium on Animal Biotechnology 2017(Jul. 05) Presenter:Sato S, Sato T, Miki S, Ono T, Takaya T, Kagami H.
学術論文査読件数 2023- , Genes Pharmaceuticals 2022- , Bioengineering Biomedicines BMC Endocrine Disorders Frontiers in Nutrition Life Journal of Functional Biomaterials Metabolites 2021- , Advanced Science BIOCELL Cellular Signalling Differentiation Frontiers in Bioengineering and Biotechnology Frontiers in Cell and Developmental Biology Frontiers in Endocrinology Frontiers in Molecular Biosciences Frontiers in Veterinary Science Heliyon International Journal of Biological Sciences Journal of Animal Science and Biotechnology Journal of Poultry Science Nutrients Onco Regenerative Therapy Stem Cells 2020- , Animals Antioxidants Cells Frontiers in Physiology Histochemistry and Cell Biology International Journal of Molecular Sciences Journal of Medical Virology Methods and Protocols Poultry Science 2019- , Animal Science Journal Current Pharmaceutical Design Journal of Diabetes Research Journal of Integrative Neuroscience 2018- , Frontiers in Immunology Journal of Oncology Journal of Veterinary Medical Science Scientific Reports 2017- , Bioscience, Biotechnology, and Biochemistry 2015- , BMC Genomics 2014- , Stem Cells International 2013- , Circulation 2013- , PLoS One
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