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中沢 洋三  ナカザワ ヨウゾウ

教員組織学術研究院(医学系)電話番号
教育組織医学部 医学科 小児医学FAX番号
職名教授メールアドレスyxnakaza@shinshu-u.ac.jp
住所ホームページURL

更新日:2022/11/18

プロフィール

研究分野
小児科学
キーワード:造血幹細胞移植 , がん免疫療法 , 遺伝子治療
学歴
出身大学院
2015 , 信州大学大学院医学系研究科

取得学位
医学博士 , 信州大学大学院医学系研究科

研究活動業績

研究業績(著書・
発表論文等)
論文
Comment on: Assessment of kidney function using inulin-based and estimated glomerular filtration rates before and after allogeneic hematopoietic stem cell transplantation in pediatric patients
PEDIATRIC BLOOD & CANCER,69(9):e29634 2022(Sep.)
Author:Matsuoka, Daisuke; Hirabayashi, Koichi; Murase, Tsubasa; Saito, Shoji; Nakazawa, Yozo;


A retrospective survey of patients who discontinued participation in the JPLSG HLH-2004 clinical trial
INTERNATIONAL JOURNAL OF HEMATOLOGY,116(3):434-441 2022(Sep.)
Author:Ono, Rintaro; Sakamoto, Kenichi; Doi, Takehiko; Yanagisawa, Ryu; Tamura, Akihiro; Hashimoto, Hiroya; Kanegane, Hirokazu; Ishii, Eiichi; Nakazawa, Yozo; Shioda, Yoko; Japan Children's Canc Grp;
Keywords:HLH-2004; Hemophagocytic lymphohistiocytosis; Epstein-Barr virus; EBV-HLH; Complications;


Skin and soft tissue infections in adolescent chronic myeloid leukemia under dasatinib treatment
PEDIATRIC BLOOD & CANCER,69(8):e29714 2022(Aug.)
Author:Uchida, Eriko; Saito, Shoji; Morita, Daisuke; Okura, Eri; Hirabayashi, Koichi; Tanaka, Miyuki; Nakazawa, Hideyuki; Minagawa, Akane; Nakazawa, Yozo;
Keywords:adolescent; cellulitis; chronic myeloid leukemia; dasatinib; skin and soft tissue infections; tyrosine kinase inhibitor;


Follow-up System for Childhood Cancer Survivors Via Germline Clinical Sequencing
The Shinshu Medical Journal,70(3):157-167 2022(Jun.)
Author:Watanabe Tatsuo, Hirabayashi Koichi, Morita Daisuke, Yamaguchi Tomomi, Okura Eri, Morokawa Hirokazu, Saito Shoji, Tanaka Miyuki, Nakazawa Yozo, Kosho Tomoki


Multi-institutional survey of malignant pleural mesothelioma patients in the Hokushin region
JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY,148(5):1153-1158 2022(May)
Author:Uramoto, Hidetaka; Takiguchi, Tomoya; Koizumi, Tomonobu; Tanimoto, Azusa; Hayashi, Ryuji; Nakazawa, Yozo; Ito, Ken-ichi; Nakada, Mitsutoshi; Hirono, Yasuo; Nishino, Yoshikazu; Yano, Seiji;
Keywords:Malignant pleural mesothelioma; Cancer registration; Cancer screening; Ganpro database; Hokushin region;


Relationship between allergic transfusion reactions and allergic predisposition among pediatric patients with hematological/oncological disease
TRANSFUSION,62(5):1035-1044 2022(May)
Author:Yanagisawa, Ryu; Ishimine, Nau; Komori, Kazutoshi; Kurata, Takashi; Saito, Shoji; Tanaka, Miyuki; Sakashita, Kazuo; Tozuka, Minoru; Nakazawa, Yozo;
Keywords:allergic rhinitis; allergic sensitization; asthma; atopic dermatitis; hay fever; pollinosis;


Multi-institutional survey of thymic carcinoma patients in Hokushin region
JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY,148(2):419-424 2022(Feb.)
Author:Uramoto, Hidetaka; Takiguchi, Tomoya; Koizumi, Tomonobu; Tanimoto, Azusa; Hayashi, Ryuji; Nakazawa, Yozo; Ito, Ken-ichi; Nakada, Mitsutoshi; Hirono, Yasuo; Nishino, Yoshikazu; Yano, Seiji;
Keywords:Thymic carcinoma; Cancer registration; Cancer screening; Ganpro database; Hokushin region;


A first-in-human clinical trial of GMR CAR-T for CD116(+) myeloid malignancies
CANCER SCIENCE,113:649-649 2022(Feb.)
Author:Saito, Shoji; Nakazawa, Yozo;


Development of a novel CAR-T cell therapy targeting ALK for small cell lung cancer
CANCER SCIENCE,113:1485-1485 2022(Feb.)
Author:Takeda, Tetsu; Hirabayashi, Koichi; Tanaka, Miyuki; Yagyu, Shigeki; Shimizu, Kimihiro; Nakazawa, Yozo;


Efficacy of tocilizumab for interstitial lung disease associated with polyarticular juvenile idiopathic arthritis
PEDIATRICS INTERNATIONAL,64(1) 2022(Jan.)
Author:Maruyama, Yuta; Shigemura, Tomonari; Kobayashi, Norimoto; Nakazawa, Yozo;
Keywords:adalimumab; interstitial lung disease; polyarticular juvenile idiopathic arthritis; tocilizumab;


Cellular congenital mesoblastic nephroma detected by prenatal MRI: a case report and literature review
TRANSLATIONAL PEDIATRICS,11(1):163-173 2022(Jan.)
Author:Liu, Tingting; Al-Kzayer, Lika'a Fasih Y.; Sarsam, Shamil Naji; Chen, Lei; Saeed, Raghad M.; Ali, Kenan Hussien; Nakazawa, Yozo;
Keywords:Congenital mesoblastic nephroma (CMN); cellular CMN; case report; prenatal MRI; ETV6;


Cancer among children, adolescents and young adults in the Hokushin region, Japan, between 2010 and 2015
JAPANESE JOURNAL OF CLINICAL ONCOLOGY,52(1):86-95 2022(Jan.)
Author:Okura, Eri; Nishino, Yoshikazu; Sakashita, Kazuo; Tanimoto, Azusa; Hayashi, Ryuji; Yoshida, Yoshio; Nakada, Mitsutoshi; Koizumi, Tomonobu; Yano, Seiji; Nakazawa, Yozo;
Keywords:epidemiological monitoring; neoplasms; cancer registry; adolescent and young adult; childhood;


Immunoglobulin G4-related orbital disease in an 8-year-old girl
PEDIATRICS INTERNATIONAL,64(1):e15014 2022(Jan.)
Author:Hoshiyama, Sayako; Maruyama, Yuta; Iwaya, Mai; Uehara, Takeshi; Nakazawa, Yozo;


Clinical Courses of IKAROS and CTLA4 Deficiencies: A Systematic Literature Review and Retrospective Longitudinal Study
FRONTIERS IN IMMUNOLOGY,12:784901 2022
Author:Hoshino, Akihiro; Toyofuku, Etsushi; Mitsuiki, Noriko; Yamashita, Motoi; Okamoto, Keisuke; Yamamoto, Michio; Kanda, Kenji; Yamato, Genki; Keino, Dai; Yoshimoto-Suzuki, Yuri; Kamizono, Junji; Onoe, Yasuhiro; Ichimura, Takuya; Nagao, Mika; Yoshimura, Masaru; Tsugawa, Koji; Igarashi, Toru; Mitsui-Sekinaka, Kanako; Sekinaka, Yujin; Doi, Takehiko; Yasumi, Takahiro; Nakazawa, Yozo; Takagi, Masatoshi; Imai, Kohsuke; Nonoyama, Shigeaki; Morio, Tomohiro; Latour, Sylvain; Kanegane, Hirokazu;
Keywords:IKAROS deficiency; CTLA4 deficiency; systematic literature review; retrospective longitudinal study; clinical course;


PiggyBac Transposon-Mediated CD19 Chimeric Antigen Receptor-T Cells Derived From CD45RA-Positive Peripheral Blood Mononuclear Cells Possess Potent and Sustained Antileukemic Function
FRONTIERS IN IMMUNOLOGY,13:770132 2022
Author:Suematsu, Masaya; Yagyu, Shigeki; Nagao, Nobuyoshi; Kubota, Susumu; Shimizu, Yuto; Tanaka, Miyuki; Nakazawa, Yozo; Imamura, Toshihiko;
Keywords:CAR-T cells; CD45RA; CAR-T cell therapy; piggyBac transposon; naive; stem cell memory-like T cells;


Dual-antigen targeted iPSC-derived chimeric antigen receptor-T cell therapy for refractory lymphoma
MOLECULAR THERAPY,30(2):534-549 2022
Author:Harada, Sakiko; Ando, Miki; Ando, Jun; Ishii, Midori; Yamaguchi, Tomoyuki; Yamazaki, Satoshi; Toyota, Tokuko; Ohara, Kazuo; Ohtaka, Manami; Nakanishi, Mahito; Shin, Chansu; Ota, Yasunori; Nakashima, Kazutaka; Ohshima, Koichi; Imai, Chihaya; Nakazawa, Yozo; Nakauchi, Hiromitsu; Komatsu, Norio;


Relationship between allergic sensitisation-associated single-nucleotide polymorphisms and allergic transfusion reactions and febrile non-haemolytic transfusion reactions in paediatric cases
BLOOD TRANSFUSION,20(2):94-102 2022
Author:Ide, Yuichiro; Yanagisawa, Ryu; Kobayashi, Jun; Komori, Kazutoshi; Matsuda, Kazuyuki; Amano, Yuji; Nakazawa, Yozo; Takeshita, Toshikazu; Sakashita, Kazuo; Tozuka, Minoru;
Keywords:ATR; children; FNHTR; polymorphism; SNP;


A Phase I/II Clinical Trial of Piggybac-Modified GMR CAR-T Cell Therapy for CD116 Positive Relapsed/Refractory Myeloid Malignancies
PEDIATRIC BLOOD & CANCER,68 2021(Nov.)
Author:Saito, Shoji; Tanaka, Miyuki; Morokawa, Hirokazu; Hirabayashi, Koichi; Inada, Yoichi; Usami, Yoko; Kojima, Shunsuke; Yanagisawa, Ryu; Nakazawa, Hideyuki; Nakazawa, Yozo;


A Retrospective Survey of the Discontinuation Cases of JPSLG HLH-2004 Clinical Trial
PEDIATRIC BLOOD & CANCER,68 2021(Nov.)
Author:Ono, Rintaro; Sakamoto, Kenichi; Doi, Takehiko; Yanagisawa, Ryu; Hashimoto, Hiroya; Tamura, Akihiro; Shioda, Yoko; Ishii, Eiichi; Nakazawa, Yozo;


Analysis of Predictive Factors of Allergic Transfusion Reaction using Allergic Disposition in Pediatric Patients with Hematological/Oncological Disease
PEDIATRIC BLOOD & CANCER,68 2021(Nov.)
Author:Yanagisawa, Ryu; Ishimine, Nau; Komori, Kazutoshi; Kurata, Takashi; Saito, Shoji; Tanaka, Miyuki; Sakashita, Kazuo; Tozuka, Minoru; Nakazawa, Yozo;


Relationship between placental weight and late-onset circulatory collapse
PEDIATRICS INTERNATIONAL,63(10):1205-1211 2021(Oct.)
Author:Nakamura, Chizuko; Miyosawa, Yukihide; Motoki, Noriko; Yanagisawa, Toshimitsu; Hirabayashi, Kanae; Ishida, Takefumi; Nakazawa, Yozo; Nakamura, Tomohiko;
Keywords:birthweight to placental weight ratio; late-onset circulatory collapse; neonate; placental weight; preterm;


Inhibition of MEK pathway enhances the antitumor efficacy of chimeric antigen receptor T cells against neuroblastoma
CANCER SCIENCE,112(10):4026-4036 2021(Oct.)
Author:Tomida, Akimasa; Yagyu, Shigeki; Nakamura, Kayoko; Kubo, Hiroshi; Yamashima, Kumiko; Nakazawa, Yozo; Hosoi, Hajime; Iehara, Tomoko;
Keywords:CAR-T cell therapy; chimeric antigen receptor; GD2; MEK inhibitor; neuroblastoma; trametinib;


Impact of acute kidney injury on overall survival in children and young adults undergoing allogeneic hematopoietic stem cell transplantation
PEDIATRIC BLOOD & CANCER,68(9):e29167 2021(Sep.)
Author:Matsuoka, Daisuke; Hirabayashi, Koichi; Murase, Tsubasa; Saito, Shoji; Nakazawa, Yozo;
Keywords:acute kidney injury; allo-HSCT; malignant; nonmalignant; overall survival;


IMPACT OF ACUTE KIDNEY INJURY ON OVERALL SURVIVAL IN CHILDREN AND YOUNG ADULTS UNDERGOING ALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANTATION
PEDIATRIC NEPHROLOGY,36(9):2939-2939 2021(Sep.)
Author:Matsuoka, Daisuke; Hirabayashi, Koichi; Murase, Tsubasa; Saito, Shoji; Nakazawa, Yozo;


Heterozygous missense variant in TRPC6 in a boy with rapidly progressive infantile nephrotic syndrome associated with diffuse mesangial sclerosis
AMERICAN JOURNAL OF MEDICAL GENETICS PART A,185(7):2175-2179 2021(Jul.)
Author:Hanafusa, Hiroaki; Hidaka, Yoshihiko; Yamaguchi, Tomomi; Shimojo, Hisashi; Tsukahara, Takanori; Murase, Tsubasa; Matsuoka, Daisuke; Chiba, Nao; Shimada, Shun; Morokawa, Hirokazu; Omori, Norio; Minoura, Hironori; Nagano, China; Takano, Kyoko; Nakamura, Katsuya; Wakui, Keiko; Fukushima, Yoshimitsu; Uehara, Takeshi; Nakazawa, Yozo; Iijima, Kazumoto; Nozu, Kandai; Kosho, Tomoki;
Keywords:diffuse mesangial sclerosis; end‐ stage renal disease; infantile nephrotic syndrome; steroid‐ resistant nephrotic syndrome; TRPC6;


Orbital Epstein-Barr virus-related post-transplant lymphoproliferative disorder in a 13-year-old girl with cord blood transplantation
TRANSPLANT INFECTIOUS DISEASE,23(3):e13536 2021(Jun.)
Author:Shigemura, Tomonari; Maruyama, Yuta; Shigeto, Shohei; Nakazawa, Yozo; Kanno, Hiroyuki;
Keywords:cord blood transplantation; Epstein-Barr virus; orbital PTLD; post-transplant lymphoproliferative disorder;


Multi-institutional survey of cancer disparities in disabled patients in the region of northwestern Japan
INTERNATIONAL JOURNAL OF CLINICAL ONCOLOGY,26(6):1009-1014 2021(Jun.)
Author:Sato, Shigeki; Tanimoto, Azusa; Yanagimura, Naohiro; Suzuki, Chiaki; Takumi, Yohei; Nishiyama, Akihiro; Yamashita, Kaname; Takeuchi, Shinji; Ohtsubo, Koushiro; Makino, Tomoe; Yoshida, Yoshio; Hirono, Yasuo; Hayashi, Ryuji; Koizumi, Tomonobu; Nakazawa, Yozo; Ito, Ken-Ichi; Motoo, Yoshiharu; Uramoto, Hidetaka; Nakada, Mitsutoshi; Nishino, Yoshikazu; Yano, Seiji;
Keywords:Disability; Cancer registration; Cancer screening; Feasibility; Hokushin region;


Investigation of risk factors associated with erythrocyte engraftment after ABO-incompatible hematopoietic stem cell transplantation
CLINICAL TRANSPLANTATION,35(6):e14300 2021(Jun.)
Author:Yanagisawa, Ryu; Nakazawa, Hideyuki; Nishina, Sayaka; Saito, Shoji; Shigemura, Tomonari; Tanaka, Miyuki; Nakazawa, Yozo;
Keywords:ABO blood type; cytomegalovirus; HLA antibody; immunohematology; isoagglutinin;


Association between pesticide usage during pregnancy and neonatal hyperbilirubinemia requiring treatment: the Japan Environment and Children's Study
PEDIATRIC RESEARCH,89(6):1565-1570 2021(May)
Author:Shibazaki, Takumi; Motoki, Noriko; Misawa, Yuka; Ohira, Satoshi; Inaba, Yuji; Kanai, Makoto; Kurita, Hiroshi; Nakazawa, Yozo; Tsukahara, Teruomi; Nomiyama, Tetsuo; Japan Environm Childrens Study Grp;


Pre-clinical development of piggyBac transposon mediated-CAR-T cells for HER2-positive sarcoma
CANCER SCIENCE,112:515-515 2021(Feb.)
Author:Nakamura, Kayoko; Yagyu, Shigeki; Hirota, Shogo; Tanaka, Miyuki; Nakazawa, Yozo;


Tumor-tropic liposome-mediated therapeutic delivery of mRNA for pediatric / adolescent and young adult cancers
CANCER SCIENCE,112:1025-1025 2021(Feb.)
Author:Saito, Shoji; Akahoshi, Eiichi; Ishihara-Sugano, Mitsuko; Yagyu, Shigeki; Nakazawa, Yozo;


Characterization of the microbiota and chemical properties of pork loins during dry aging
MICROBIOLOGYOPEN,10(1):e1157 2021(Jan.)
Author:Endo, Akihito; Koizumi, Ryosuke; Nakazawa, Yozo; Shiwa, Yuh; Maeno, Shintaro; Kido, Yoshihiko; Irisawa, Tomohiro; Muramatsu, Yoshiki; Tada, Kotaro; Yamazaki, Masao; Myoda, Takao;
Keywords:aroma; Debaryomyces; dry-aging pork; microbiota; proteolysis; Pseudomonas;


Mutated GM-CSF-based CAR-T cells targeting CD116/CD131 complexes exhibit enhanced anti-tumor effects against acute myeloid leukaemia
CLINICAL & TRANSLATIONAL IMMUNOLOGY,10(5):e1282 2021
Author:Hasegawa, Aiko; Saito, Shoji; Narimatsu, Shogo; Nakano, Shigeru; Nagai, Mika; Ohnota, Hideki; Inada, Yoichi; Morokawa, Hirokazu; Nakashima, Ikumi; Morita, Daisuke; Ide, Yuichiro; Matsuda, Kazuyuki; Tashiro, Haruko; Yagyu, Shigeki; Tanaka, Miyuki; Nakazawa, Yozo;
Keywords:AML; CD116; GM-CSF; GM-CSF receptor; GMR; low affinity;


A lymphodepleted non-human primate model for the assessment of acute on-target and off-tumor toxicity of human chimeric antigen receptor-T cells
CLINICAL & TRANSLATIONAL IMMUNOLOGY,10(6):e1291 2021
Author:Yagyu, Shigeki; Mochizuki, Hidemi; Yamashima, Kumiko; Kubo, Hiroshi; Saito, Shoji; Tanaka, Miyuki; Sakamoto, Kengo; Shimoi, Akihito; Nakazawa, Yozo;
Keywords:CAR-T cells; cell therapy; lymphodepletion; non-human primate; off-target toxicity; on-target toxicity;


Development of Dry Sausage that Utilizes the Food Physico-chemical Characteristics of Emu Tendon Meat
JOURNAL OF THE JAPANESE SOCIETY FOR FOOD SCIENCE AND TECHNOLOGY-NIPPON SHOKUHIN KAGAKU KOGAKU KAISHI,68(12):447-454 2021
Author:Nakazawa, Yozo; Yoshida, Ayano; Kashima, Haruhiko; Satake, Eri; Ito, Hiroka; Tamechika, Yume; Moritake, Ryosuke; Minami, Kazuhiro; Sagane, Yoshimasa;
Keywords:emu; tendon meat; dry sausage; collagen; gelatin;


Development of non-viral, ligand-dependent, EPHB4-specific chimeric antigen receptor T cells for treatment of rhabdomyosarcoma
MOLECULAR THERAPY-ONCOLYTICS,20:646-658 2021
Author:Kubo, Hiroshi; Yagyu, Shigeki; Nakamura, Kayoko; Yamashima, Kumiko; Tomida, Akimasa; Kikuchi, Ken; Iehara, Tomoko; Nakazawa, Yozo; Hosoi, Hajime;


Autologous antigen-presenting cells efficiently expand piggyBac transposon CAR-T cells with predominant memory phenotype
MOLECULAR THERAPY-METHODS & CLINICAL DEVELOPMENT,21:315-324 2021
Author:Nakamura, Kayoko; Yagyu, Shigeki; Hirota, Shogo; Tomida, Akimasa; Kondo, Makoto; Shigeura, Tomokuni; Hasegawa, Aiko; Tanaka, Miyuki; Nakazawa, Yozo;


Non-Viral Delivery of Therapeutic mRNA Using Tumor-Tropic Liposomes for the Treatment of Solid Tumors
MOLECULAR THERAPY,29(4):226-227 2021
Author:Saito, Shoji; Nakashima, Ikumi; Akahoshi, Eiichi; Ishihara-Sugano, Mitsuko; Yagyu, Shigeki; Nakazawa, Yozo;


Piggybac Transposon Mediated CD19 CAR-T Cells Derived from CD45RA-Positive PBMCs Possess Potent and Sustained Antileukemic Function
BLOOD,138 2021
Author:Suematsu, Masaya; Yagyu, Shigeki; Nagao, Nobuyoshi; Kubota, Susumu; Shimizu, Yuto; Tanaka, Miyuki; Nakazawa, Yozo; Imamura, Toshihiko;


A Phase I/II Clinical Trial of Piggybac-Modified GMR CAR-T Cell Therapy for CD116 Positive Relapsed/Refractory Myeloid Malignancies
BLOOD,138 2021
Author:Saito, Shoji; Tanaka, Miyuki; Hasegawa, Aiko; Inada, Yoichi; Morokawa, Hirokazu; Usami, Yoko; Kojima, Shunsuke; Yanagisawa, Ryu; Miyazawa, Chinatsu; Ito, Keiko; Sakai, Hitoshi; Nakazawa, Hideyuki; Tashiro, Haruko; Yagyu, Shigeki; Nakazawa, Yozo;


NUDT15 variants confer high incidence of second malignancies in children with acute lymphoblastic leukemia
BLOOD ADVANCES,5(23):5420-5428 2021
Author:Yoshida, Masanori; Nakabayashi, Kazuhiko; Yang, Wentao; Sato-Otsubo, Aiko; Tsujimoto, Shin-Ichi; Ogata-Kawata, Hiroko; Kawai, Tomoko; Ishiwata, Keisuke; Sakamoto, Mika; Okamura, Kohji; Yoshida, Kaoru; Shirai, Ryota; Osumi, Tomoo; Moriyama, Takaya; Nishii, Rina; Takahashi, Hiroyuki; Kiyotani, Chikako; Shioda, Yoko; Terashima, Keita; Ishimaru, Sae; Yuza, Yuki; Takagi, Masatoshi; Arakawa, Yuki; Kinoshita, Akitoshi; Hino, Moeko; Imamura, Toshihiko; Hasegawa, Daisuke; Nakazawa, Yozo; Okuya, Mayuko; Kakuda, Harumi; Takasugi, Nao; Inoue, Akiko; Ohki, Kentaro; Yoshioka, Takako; Ito, Shuichi; Tomizawa, Daisuke; Koh, Katsuyoshi; Matsumoto, Kimikazu; Sanada, Masashi; Kiyokawa, Nobutaka; Ohara, Akira; Ogawa, Seishi; Manabe, Atsushi; Niwa, Akira; Hata, Kenichiro; Yang, Jun J.; Kato, Motohiro;


Impact of infliximab administration before plasma exchange therapy on patients with Kawasaki disease
THERAPEUTIC APHERESIS AND DIALYSIS,24(6):718-724 2020(Dec.)
Author:Shimada, Shun; Matsuoka, Daisuke; Murase, Tsubasa; Hachiya, Akira; Motoki, Noriko; Nakazawa, Yozo;
Keywords:child; cytokines; infliximab; Kawasaki disease; plasma exchange;


Hematopoietic stem cell transplantation in children and adolescents with nonremission acute lymphoblastic leukemia
PEDIATRIC BLOOD & CANCER,67(12):e28732 2020(Dec.)
Author:Okamoto, Yasuhiro; Nakazawa, Yozo; Inoue, Masami; Watanabe, Kenichiro; Goto, Hiroaki; Yoshida, Nao; Noguchi, Maiko; Kikuta, Atsushi; Kato, Koji; Hashii, Yoshiko; Atsuta, Yoshiko; Kato, Motohiro;
Keywords:acute lymphoblastic leukemia; allogeneic hematopoietic stem cell transplantation; pediatrics; survival;


Assessment of kidney function using inulin-based and estimated glomerular filtration rates before and after allogeneic hematopoietic stem cell transplantation in pediatric patients
PEDIATRIC BLOOD & CANCER,67(12):e28733 2020(Dec.)
Author:Matsuoka, Daisuke; Hirabayashi, Koichi; Murase, Tsubasa; Saito, Shoji; Hidaka, Yoshihiko; Nakazawa, Yozo;
Keywords:allo-HSCT; estimated GFR; inulin clearance;


A First-in-Human Clinical Trial of Novel Chimeric Antigen Receptor T-Cell Therapy Targeting Granulocyte-Macrophage Colony-Stimulating Factor Receptor for Acute Myeloid Leukemia
PEDIATRIC BLOOD & CANCER,67 2020(Dec.)
Author:Saito, Shoji; Hasegawa, Aiko; Tanaka, Miyuki; Morokawa, Hirokazu; Morita, Daisuke; Inada, Yoichi; Kojima, Shunsuke; Yanagisawa, Ryu; Yagyu, Shigeki; Nakazawa, Yozo;


Clinical Development of piggyBac-Mediated CAR T Cells for the Treatment of Childhood and AYA Cancers
PEDIATRIC BLOOD & CANCER,67 2020(Dec.)
Author:Nakazawa, Yozo;


Tumor-Tropic Liposome-Based Delivery of Therapeutic mRNA for T Cell Leukemias
PEDIATRIC BLOOD & CANCER,67 2020(Dec.)
Author:Saito, Shoji; Nakashima, Ikumi; Hasegawa, Aiko; Akahoshi, Eiichi; Sugano, Mitsuko; Yagyu, Shigeki; Nakazawa, Yozo;


Analysis for Allergic Sensitization-Associated Single-Nucleotide Polymorphisms in Blood-Transfused Patients with Hematological and Oncological Disease
PEDIATRIC BLOOD & CANCER,67 2020(Dec.)
Author:Ide, Yuichiro; Yanagisawa, Ryu; Kobayashi, Jun; Komori, Kazutoshi; Matuda, Kazuyuki; Amano, Yuji; Nakazawa, Yozo; Takeshita, Toshikazu; Sakashita, Kazuo; Tozuka, Minoru;


A Long-Term Follow-Up System Incorporating Clinical Sequences of Hereditary Cancer Related Genes for Childhood Cancer Survivors in Our Hospital
PEDIATRIC BLOOD & CANCER,67 2020(Dec.)
Author:Watanabe, Tatsuo; Morita, Daisuke; Morokawa, Hirokazu; Okura, Eri; Hirabayashi, Koichi; Saito, Shoji; Tanaka, Miyuki; Yamaguchi, Tomomi; Kosho, Tomoki; Nakazawa, Yozo;


A Rapid Cytologic Double Staining of Epstein-Barr Virus-encoded Small RNA and Cell Surface Markers for Diagnosis of Epstein-Barr Virus-associated Hemophagocytic Lymphohistiocytosis
JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY,42(8):E756-E758 2020(Nov.)
Author:Takahashi, Natsuki; Kudo, Ko; Tanaka, Miyuki; Kumagai, Naoya; Sato, Tomohiko; Kamio, Takuya; Sasaki, Shinya; Terui, Kiminori; Kurose, Akira; Yanagisawa, Ryu; Nakazawa, Yozo; Ito, Etsuro;
Keywords:hemophagocytic lymphohistiocytosis; Epstein-Barr virus; Epstein-Barr virus– encoded small RNA; cytologic diagnosis;


Trends in gastroesophageal reflux disease in Japanese children and adolescents
PEDIATRICS INTERNATIONAL,62(11):1269-1274 2020(Nov.)
Author:Kusakari, Mai; Nakayama, Yoshiko; Horiuchi, Akira; Nakazawa, Yozo;
Keywords:adolescents; Barrett’ s esophagus; children; gastroesophageal reflux disease; reflux esophagitis;


Impact of immunophenotypic characteristics on genetic subgrouping in childhood acute lymphoblastic leukemia: Tokyo Children's Cancer Study Group (TCCSG) studyL04-16
GENES CHROMOSOMES & CANCER,59(10):551-561 2020(Oct.)
Author:Ohki, Kentaro; Takahashi, Hiroyuki; Fukushima, Takashi; Nanmoku, Toru; Kusano, Shinpei; Mori, Makiko; Nakazawa, Yozo; Yuza, Yuki; Migita, Masahiro; Okuno, Haruna; Morimoto, Akira; Yoshino, Hiroshi; Kato, Motohiro; Hayashi, Yasuhide; Manabe, Atsushi; Ohara, Akira; Hasegawa, Daisuke; Inukai, Takeshi; Tomizawa, Daisuke; Koh, Katsuyoshi; Kiyokawa, Nobutaka; Tokyo Childrens Canc Study Grp;
Keywords:acute lymphoblastic leukemia; flow cytometry; genetic mutations; immunophenotype; novel fusion genes;


Transfusion outcome for volume- and plasma-reduced platelet concentrates for pediatric patients
TRANSFUSION AND APHERESIS SCIENCE,59(4):102776 2020(Aug.)
Author:Tanaka, Miyuki; Yanagisawa, Ryu; Yamanaka, Manjiro; Konno, Saori; Takemura, Kayo; Kojima, Shunsuke; Okura, Eri; Morita, Daisuke; Saito, Shoji; Komori, Kazutoshi; Matsuzawa, Haruka; Sakashita, Kazuo; Tozuka, Minoru; Nakazawa, Yozo;
Keywords:Washed platelet concentrate; Allergic transfusion reaction; Pediatric transfusion;


Long-term outcomes of children with extracutaneous juvenile xanthogranulomas in Japan
PEDIATRIC BLOOD & CANCER,67(7):e28381 2020(Jul.)
Author:Maeda, Miho; Morimoto, Akira; Shioda, Yoko; Asano, Takeshi; Koga, Yuhki; Nakazawa, Yozo; Kanegane, Hirokazu; Kudo, Kazuko; Ohga, Shouichi; Ishii, Eiichi; Japanese Soc Pediat Hematology Onc;
Keywords:extracutaneous juvenile xanthogranuloma; intracranial lesions; non-Langerhans cell histiocytosis; permanent sequelae; pituitary dysfunction;


Heart rate variability in the course of chemotherapy and haematopoietic stem cell transplantation for peadiatric patients with haematological malignancies
CARDIOLOGY IN THE YOUNG,30(7):967-974 2020(Jul.)
Author:Kobayashi, Honami; Motoki, Noriko; Yokota, Saori; Kanai, Ayako; Yamazaki, Shoko; Utsumi, Masafumi; Nakazawa, Yozo;
Keywords:Heart rate variability; autonomic nervous system; leukemia; lymphoma; haematopoietic stem cell transplantation;


Changes in laboratory findings in parechovirus-A infection in nine neonates and infants
PEDIATRICS INTERNATIONAL,62(6):755-758 2020(Jun.)
Author:Nimura, Keiko; Maruyama, Yuta; Aizawa, Yuta; Saitoh, Akihiko; Nakazawa, Yozo;
Keywords:hemophagocytic lymphohistiocytosis; hyperferritinemia; infant; neonates; parechovirus A;


Comparative analysis of graft-versus-host disease prophylaxis with tacrolimus in combination with methylprednisolone or methotrexate after umbilical cord blood transplantation
INTERNATIONAL JOURNAL OF HEMATOLOGY,111(5):702-710 2020(May)
Author:Shigemura, Tomonari; Sakashita, Kazuo; Okura, Eri; Morita, Daisuke; Komori, Kazutoshi; Kurata, Takashi; Hirabayashi, Koichi; Saito, Shoji; Tanaka, Miyuki; Yanagisawa, Ryu; Nakazawa, Yozo;
Keywords:Graft-versus-host disease; Prophylaxis; Umbilical cord blood transplantation; Corticosteroid; Methotrexate; Tacrolimus;


Hematopoietic stem cell transplantation for pediatric acute promyelocytic leukemia in Japan
PEDIATRIC BLOOD & CANCER,67(5):e28181 2020(May)
Author:Yamamoto, Shohei; Tomizawa, Daisuke; Kudo, Kazuko; Hasegawa, Daiichiro; Taga, Takashi; Yanada, Masamitsu; Kondo, Tadakazu; Nakazawa, Yozo; Eto, Tetsuya; Inoue, Masami; Kato, Koji; Atsuta, Yoshiko; Ishida, Hiroyuki;
Keywords:acute promyelocytic leukemia; hematopoietic stem cell transplantation; pediatric; relapse;


Thyroid tumor surveillance using ultrasound in childhood cancer survivors
PEDIATRICS INTERNATIONAL,62(5):562-568 2020(May)
Author:Furui, Yu; Morita, Daisuke; Okura, Eri; Komori, Kazutoshi; Saito, Shoji; Hirabayashi, Kanae; Tanaka, Miyuki; Nakazawa, Yozo;
Keywords:childhood cancer survivor; fine needle aspiration; secondary cancer; thyroid tumor; ultrasound;


Hematopoietic stem cell transplantation for pediatric acute promyelocytic leukemia in Japan
Pediatr Blood Cancer,67(5):e28181 2020(May)
Author:Yamamoto S, Tomizawa D, Kudo K, Hasegawa D, Taga T, Yanada M, Kondo T, Nakazawa Y, Eto T, Inoue M, Kato K, Atsuta Y, Ishida H.


Comparative analysis of graft-versus-host disease prophylaxis with tacrolimus in combination with methylprednisolone or methotrexate after umbilical cord blood transplantation
Int J Hematol,111(5):702-710 2020(May)
Author:Shigemura T, Sakashita K, Okura E, Morita D, Komori K, Kurata T, Hirabayashi K, Saito S, Tanaka M, Yanagisawa R, Nakazawa Y.


Delayed methotrexate clearance and acute kidney injury after high-dose methotrexate chemotherapy concurrent with dasatinib in a patient with relapsed Philadelphia chromosome-positive acute lymphoblastic leukemia: A case report
PEDIATRIC BLOOD & CANCER,67(4):e28173 2020(Apr.)
Author:Morota, Haruka; Saito, Shoji; Uchida, Eriko; Okura, Eri; Matsuoka, Daisuke; Hidaka, Yoshihiko; Natsume, Takenori; Watanabe, Tatsuo; Shigemura, Tomonari; Morita, Daisuke; Tanaka, Miyuki; Kurata, Takashi; Sakashita, Kazuo; Nakazawa, Yozo;


Usefulness of Continuous Glucose Monitoring for Prevention and Early Detection of Hypoglycemia Caused by a Ketogenic Diet and Late
PEDIATRIC NEUROLOGY,105:65-66 2020(Apr.)
Author:Morikawa, Manami; Hara, Yosuke; Nakazawa, Yozo; Inaba, Yuji; Motobayashi, Mitsuo;
Keywords:Late dumping syndrome; Electrical status epilepticus during slow-wave sleep syndrome; Ketogenic diet; Continuous glucose monitoring;


Usefulness of Continuous Glucose Monitoring for Prevention and Early Detection of Hypoglycemia Caused by a Ketogenic Diet and Late Dumping Syndrome
Pediatr Neurol,105:65-66 2020(Apr.)
Author:Morikawa M, Hara Y, Nakazawa Y, Inaba Y, Motobayashi M.


Delayed methotrexate clearance and acute kidney injury after high-dose methotrexate chemotherapy concurrent with dasatinib in a patient with relapsed Philadelphia chromosome-positive acute lymphoblastic leukemia: A case report
Pediatr Blood Cancer,67(4):e28173 2020(Apr.)
Author:Morota H, Saito S, Uchida E, Okura E, Matsuoka D, Hidaka Y, Natsume T, Watanabe T, Shigemura T, Morita D, Tanaka M, Kurata T, Sakashita K, Nakazawa Y.


Complete measurable residual disease response after combination chemotherapy with AML-type and ALL-type regimens in pediatric B/myeloid acute bilineal leukemia
Leuk Lymphoma,61(4):967-970 2020(Apr.)
Author:Saito S, Taira C, Matsuda K, Yanagisawa R, Morita D, Shigemura T, Yoshikawa K, Tanaka M, Sakashita K, Mukai S, Shimodaira S, Koike K, Nakazawa Y.


PCDH17 functions as a common tumor suppressor gene in acute leukemia and its transcriptional downregulation is mediated primarily by aberrant histone acetylation, not DNA methylation
INTERNATIONAL JOURNAL OF HEMATOLOGY,111(3):451-462 2020(Mar.)
Author:Thanh Nha Uyen, Le; Amano, Yuji; Al-Kzayer, Lika'a Fasih Y.; Kubota, Noriko; Kobayashi, Jun; Nakazawa, Yozo; Koike, Kenichi; Sakashita, Kazuo;
Keywords:PCDH17 gene; Protocadherin; Leukemia; Histone acetylation; DNA methylation;


PCDH17 functions as a common tumor suppressor gene in acute leukemia and its transcriptional downregulation is mediated primarily by aberrant histone acetylation, not DNA methylation
Int J Hematol,111(3):451-462 2020(Mar.)
Author:Thanh Nha Uyen L, Amano Y, Al-Kzayer LFY, Kubota N, Kobayashi J, Nakazawa Y, Koike K, Sakashita K.


Impact of infliximab administration before plasma exchange therapy on patients with Kawasaki disease
Ther Apher Dial 2020(Feb. 19)
Author:Shimada S, Matsuoka D, Murase T, Hachiya A, Motoki N, Nakazawa Y.


Dexamethasone palmitate is a feasible option for the treatment of chronic graft-vs-host disease, particularly with macrophage hyperactivation
PEDIATRIC TRANSPLANTATION,24(1):e13627 2020(Feb.)
Author:Kurosawa, Yoshinaga; Morita, Daisuke; Shibazaki, Takumi; Komori, Kazutoshi; Motobayashi, Mitsuo; Shigemura, Tomonari; Tanaka, Miyuki; Nakazawa, Yozo;
Keywords:chronic graft-vs-host disease; dexamethasone palmitate; liposteroid; macrophage hyperactivation; serositis;


Multiple heterogeneous bone invasions of B lymphoblastic lymphoma with the TCF3/PBX1 fusion gene: a case report
INTERNATIONAL JOURNAL OF HEMATOLOGY,111(2):163-165 2020(Feb.)
Author:Okura, Eri; Saito, Shoji; Natsume, Takenori; Morita, Daisuke; Tanaka, Miyuki; Kiyokawa, Nobutaka; Nakazawa, Yozo;
Keywords:PET; Lymphoblastic lymphoma; Pediatric hematology; TCF3-PBX1; B-LBL;


Dexamethasone palmitate is a feasible option for the treatment of chronic graft-vs-host disease, particularly with macrophage hyperactivation
Pediatr Transplant,24(1):e13627 2020(Feb.)
Author:Kurosawa Y, Morita D, Shibazaki T, Komori K, Motobayashi M, Shigemura T, Tanaka M, Nakazawa Y.


Multiple heterogeneous bone invasions of B lymphoblastic lymphoma with the TCF3/PBX1 fusion gene: a case report
Int J Hematol,111(2):163-165 2020(Feb.)
Author:Okura E, Saito S, Natsume T, Morita D, Tanaka M, Kiyokawa N, Nakazawa Y.


Complete measurable residual disease response after combination chemotherapy with AML-type and ALL-type regimens in pediatric B/myeloid acute bilineal leukemia
LEUKEMIA & LYMPHOMA,61(4):967-970 2020
Author:Saito, Shoji; Taira, Chiaki; Matsuda, Kazuyuki; Yanagisawa, Ryu; Morita, Daisuke; Shigemura, Tomonari; Yoshikawa, Kentaro; Tanaka, Miyuki; Sakashita, Kazuo; Mukai, Saki; Shimodaira, Shigetaka; Koike, Kenichi; Nakazawa, Yozo;


Utility of Starch from the New Potato Variety 'Pearl Starch' in Beer Brewing
JOURNAL OF THE JAPANESE SOCIETY FOR FOOD SCIENCE AND TECHNOLOGY-NIPPON SHOKUHIN KAGAKU KOGAKU KAISHI,67(9):324-331 2020
Author:Nakazawa, Yozo; Watanabe, Takumi; Noda, Takahiro; Yamazaki, Masao;
Keywords:potato; 'Pearl Starch'; starch; beer; brewing competence;


Autologous non-human primate model for safety assessment of piggyBac transposon-mediated chimeric antigen receptor T cells on granulocyte-macrophage colony-stimulating factor receptor
CLINICAL & TRANSLATIONAL IMMUNOLOGY,9(11):e1207 2020
Author:Morokawa, Hirokazu; Yagyu, Shigeki; Hasegawa, Aiko; Tanaka, Miyuki; Saito, Shoji; Mochizuki, Hidemi; Sakamoto, Kengo; Shimoi, Akihito; Nakazawa, Yozo;
Keywords:CAR T cells; hGMR; non-human primate; off-tumor toxicity; cynomolgus macaque;


Combination Therapy of GD2-Specific CAR-T Cells with Tyrosine Kinase Inhibitors for Neuroblastoma
MOLECULAR THERAPY,28(4):146-146 2020
Author:Tomida, Akimasa; Yagyu, Shigeki; Yamashima, Kumiko; Kubo, Hiroshi; Iehara, Tomoko; Nakamura, Kayoko; Nakazawa, Yozo; Hosoi, Hajime;


Tumor-Tropic Liposome-Mediated Therapeutic Delivery of mRNA for T Cell Malignancies
MOLECULAR THERAPY,28(4):10-11 2020
Author:Saito, Shoji; Nakashima, Ikumi; Hasegawa, Aiko; Akahoshi, Eiichi; Ishihara-Sugano, Mitsuko; Yagyu, Shigeki; Nakazawa, Yozo;


Direct Delivery of piggyBac CD19 CAR T Cells Has Potent Anti-tumor Activity against ALL Cells in CNS in a Xenograft Mouse Model
MOLECULAR THERAPY-ONCOLYTICS,18:37-46 2020
Author:Tanaka, Kuniaki; Kato, Itaru; Tanaka, Miyuki; Morita, Daisuke; Matsuda, Kazuyuki; Takahashi, Yoshiyuki; Nakahata, Tatsutoshi; Umeda, Katsutsugu; Hiramatsu, Hidefumi; Adachi, Souichi; Takita, Junko; Nakazawa, Yozo;


Mutated GM-CSF-Based CAR T-Cells Targeting CD116/CD131 Complexes Exhibit Enhanced Anti-Tumor Effects Against Acute Myeloid Leukemia
BLOOD,136 2020
Author:Saito, Shoji; Hasegawa, Aiko; Nagai, Mika; Inada, Yoichi; Morokawa, Hirokazu; Nakashima, Ikumi; Morita, Daisuke; Ide, Yuichiro; Matsuda, Kazuyuki; Tashiro, Haruko; Yagyu, Shigeki; Tanaka, Miyuki; Nakazawa, Yozo;


Tumor-Tropic Liposome-Mediated Therapeutic Delivery of mRNA for T Cell Malignancies
BLOOD,136 2020
Author:Saito, Shoji; Nakashima, Ikumi; Hasegawa, Aiko; Akahoshi, Eiichi; Ishihara-Sugano, Mitsuko; Yagyu, Shigeki; Nakazawa, Yozo;


Comprehensive Genetic Analysis Revealed Myeloid/Natural Killer (NK) Cell Precursor Acute Leukemia As a Novel Distinctive Leukemia Entity
BLOOD,136 2020
Author:Nishimura, Akira; Yokoyama, Kazuaki; Yamagishi, Chika; Imamura, Toshihiko; Naruto, Takuya; Morio, Tomohiro; Tanaka, Yukie; Kanai, Akinori; Matsui, Hirotaka; Higuchi, Naoko; Takada, Akiko; Okuno, Haruna; Saito, Shoji; Karakawa, Shuhei; Kobayashi, Shogo; Hasegawa, Daisuke; Fujisaki, Hiroyuki; Hasegawa, Daiichiro; Koike, Kazutoshi; Koike, Takashi; Rai, Shinya; Umeda, Katsutsugu; Sano, Hideki; Sekinaka, Yujin; Ogawa, Atsushi; Kinoshita, Akitoshi; Shiba, Norio; Miki, Mizuka; Kimura, Fumihiko; Nakayama, Hideki; Nakazawa, Yozo; Taga, Takashi; Taki, Tomohiko; Adachi, Souichi; Manabe, Atsushi; Koh, Katsuyoshi; Ishida, Yasushi; Tojo, Arinobu; Takagi, Masatoshi;


NUDT15 Variants Confer High Incidence of Secondary Malignancies of ALL in Children
PEDIATRIC BLOOD & CANCER,66:S5-S6 2019(Dec.)
Author:Yoshida, Masanori; Nakabayashi, Kazuhiko; Sato, Aiko; Tsujimoto, Shinichi; Yoshida, Kaoru; Shirai, Ryota; Osumi, Tomoo; Yuza, Yuki; Takagi, Masatoshi; Takahashi, Hiroyuki; Koh, Katsuyoshi; Kinoshita, Akitoshi; Hino, Moeko; Imamura, Toshihiko; Nakazawa, Yozo; Okuya, Mayuko; Kakuda, Harumi; Sanada, Masashi; Matsumoto, Kimikazu; Tomizawa, Daisuke; Kiyokawa, Nobutaka; Ohara, Akira; Manabe, Atsushi; Hata, Kenichiro; Yang, Jun; Kato, Motohiro;


Development of piggyBac Transposon-Mediated GD2 Specific CAR-T Cells Targeting Neuroblastoma
PEDIATRIC BLOOD & CANCER,66:S14-S15 2019(Dec.)
Author:Tomida, Akimasa; Yagyu, Shigeki; Yamashima, Kumiko; Yoshida, Hideki; Miyachi, Mitsuru; Tsuchiya, Kunihiko; Iehara, Tomoko; Nakazawa, Yozo; Hosoi, Hajime;


A Long-Term Follow-Up System Incorporating Clinical Sequences of Hereditary Cancer Related Genes for Childhood Cancer Survivors in our Hospital
PEDIATRIC BLOOD & CANCER,66:S102-S102 2019(Dec.)
Author:Watanabe, Tatsuo; Morita, Daisuke; Morokawa, Hirokazu; Okura, Eri; Hirabayashi, Koichi; Saito, Shoji; Tanaka, Miyuki; Yamaguchi, Tomomi; Kosho, Tomoki; Nakazawa, Yozo;


Clinical Development of piggyBac Transposon Mediated-CAR-T Cells For Osteosarcoma
PEDIATRIC BLOOD & CANCER,66:S14-S14 2019(Dec.)
Author:Nakamura, Kayoko; Tanaka, Miyuki; Hasegawa, Aiko; Kondo, Makoto; Shigeura, Tomokuni; Okada, Masahiro; Yagyu, Shigeki; Nakazawa, Yozo;


Mucormycosis Complicated with Streptococcal Bacteremia During Early Consolidation Therapy for Acute Lymphoblastic Leukemia
PEDIATRIC BLOOD & CANCER,66:S30-S31 2019(Dec.)
Author:Fukushima, Keitaro; Ishikawa, Makoto; Okuya, Mayuko; Sato, Yuya; Maruyama, Yuta; Shigemura, Tomonari; Nakazawa, Yozo; Yoshihara, Shigemi;


Evaluating the Safety of piggyBac Transposon-mediated GMR CAR-T Cells Using a Non-human Primate Model
PEDIATRIC BLOOD & CANCER,66:S6-S6 2019(Dec.)
Author:Morokawa, Hirokazu; Tanaka, Miyuki; Saito, Shoji; Mochizuki, Hidemi; Shimoi, Akihito; Yagyu, Shigeki; Nakazawa, Yozo;


A Rapid Cytologic Double Staining of Epstein-Barr Virus-encoded Small RNA and Cell Surface Markers for Diagnosis of Epstein-Barr Virus-associated Hemophagocytic Lymphohistiocytosis
J Pediatr Hematol Oncol 2019(Nov. 14)
Author:Takahashi N, Kudo K, Tanaka M, Kumagai N, Sato T, Kamio T, Sasaki S, Terui K, Kurose A, Yanagisawa R, Nakazawa Y, Ito E.


Retrospective analysis of children with high-risk acute myeloid leukemia who underwent allogeneic hematopoietic stem cell transplantation following complete remission with initial induction chemotherapy in the AML-05 clinical trial
PEDIATRIC BLOOD & CANCER,66(10):e27875 2019(Oct.)
Author:Hyakuna, Nobuyuki; Hashii, Yoshiko; Ishida, Hiroyuki; Umeda, Katsutsugu; Takahashi, Yoshiyuki; Nagasawa, Masayuki; Yabe, Hiromasa; Nakazawa, Yozo; Koh, Katsuyoshi; Goto, Hiroaki; Fujisaki, Hiroyuki; Matsumoto, Kimikazu; Kakuda, Harumi; Yano, Michihiro; Tawa, Akio; Tomizawa, Daisuke; Taga, Takashi; Adachi, Souichi; Kato, Koji;
Keywords:AML; clinical trials; graft-versus-host disease; stem cell transplantation;


Prevention of transfusion-transmitted cytomegalovirus infection using leukoreduced blood components in patients receiving seronegative umbilical cord blood transplantation
TRANSFUSION,59(10):3065-3070 2019(Oct.)
Author:Shigemura, Tomonari; Yanagisawa, Ryu; Komori, Kazutoshi; Morita, Daisuke; Kurata, Takashi; Tanaka, Miyuki; Sakashita, Kazuo; Nakazawa, Yozo;


Essential role of PTPN11 mutation in enhanced haematopoietic differentiation potential of induced pluripotent stem cells of juvenile myelomonocytic leukaemia
BRITISH JOURNAL OF HAEMATOLOGY,187(2):163-173 2019(Oct.)
Author:Shigemura, Tomonari; Matsuda, Kazuyuki; Kurata, Takashi; Sakashita, Kazuo; Okuno, Yusuke; Muramatsu, Hideki; Yue, Fengming; Ebihara, Yasuhiro; Tsuji, Kohichiro; Sasaki, Katsunori; Nakahata, Tatsutoshi; Nakazawa, Yozo; Koike, Kenichi;
Keywords:juvenile myelomonocytic leukaemia; PTPN11 mutation; induced pluripotent stem cell; AGM-S3; haematopoietic differentiation;


Prevention of transfusion-transmitted cytomegalovirus infection using leukoreduced blood components in patients receiving seronegative umbilical cord blood transplantation
Transfusion,59(10):3065-3070 2019(Oct.)
Author:Shigemura T, Yanagisawa R, Komori K, Morita D, Kurata T, Tanaka M, Sakashita K, Nakazawa Y.


Retrospective analysis of children with high-risk acute myeloid leukemia who underwent allogeneic hematopoietic stem cell transplantation following complete remission with initial induction chemotherapy in the AML-05 clinical trial
Pediatr Blood Cancer,66(10):e27875 2019(Oct.)
Author:Hyakuna N, Hashii Y, Ishida H, Umeda K, Takahashi Y, Nagasawa M, Yabe H, Nakazawa Y, Koh K, Goto H, Fujisaki H, Matsumoto K, Kakuda H, Yano M, Tawa A, Tomizawa D, Taga T, Adachi S, Kato K.


Essential role of PTPN11 mutation in enhanced haematopoietic differentiation potential of induced pluripotent stem cells of juvenile myelomonocytic leukaemia
Br J Haematol,187(2):163-173 2019(Oct.)
Author:Shigemura T, Matsuda K, Kurata T, Sakashita K, Okuno Y, Muramatsu H, Yue F, Ebihara Y, Tsuji K, Sasaki K, Nakahata T, Nakazawa Y, Koike K.


Hematopoietic stem-cell transplantation in children with refractory acute myeloid leukemia
BONE MARROW TRANSPLANTATION,54(9):1489-1498 2019(Sep.)
Author:Okamoto, Yasuhiro; Kudo, Kazuko; Tabuchi, Ken; Tomizawa, Daisuke; Taga, Takashi; Goto, Hiroaki; Yabe, Hiromasa; Nakazawa, Yozo; Koh, Katsuyoshi; Ikegame, Kazuhiro; Yoshida, Nao; Uchida, Naoyuki; Watanabe, Kenichiro; Koga, Yuuki; Inoue, Masami; Kato, Koji; Atsuta, Yoshiko; Ishida, Hiroyuki;


Proton Beam Therapy for Adolescent Primary Central Nervous System Lymphoma With Residual Tumor After Intensive Chemotherapy: A Case Report
Pract Radiat Oncol,9(5):333-337 2019(Sep.)
Author:Komori K, Saito S, Araya M, Morita D, Kurata T, Hirabayashi K, Tanaka M, Koiwai K, Tauchi K, Masaki H, Nakazawa Y.


Hematopoietic stem-cell transplantation in children with refractory acute myeloid leukemia
Bone Marrow Transplant,54(9):1489-1498 2019(Sep.)
Author:Okamoto Y, Kudo K, Tabuchi K, Tomizawa D, Taga T, Goto H, Yabe H, Nakazawa Y, Koh K, Ikegame K, Yoshida N, Uchida N, Watanabe K, Koga Y, Inoue M, Kato K, Atsuta Y, Ishida H.


Maternal Exposure to Housing Renovation During Pregnancy and Risk of Offspring with Congenital Malformation: The Japan Environment and Children's Study
Sci Rep,9(1):11564 2019(Aug. 09)
Author:Motoki N, Inaba Y, Shibazaki T, Misawa Y, Ohira S, Kanai M, Kurita H, Nakazawa Y, Tsukahara T, Nomiyama T; Japan Environment & Children’s Study (JECS) Group.


Alcohol Consumption During Pregnancy and Risk of Placental Abnormality: The Japan Environment and Children's Study
Sci Rep,9(1):10259 2019(Jul. 16)
Author:Ohira S, Motoki N, Shibazaki T, Misawa Y, Inaba Y, Kanai M, Kurita H, Shiozawa T, Nakazawa Y, Tsukahara T, Nomiyama T; Japan Environment & Children’s Study (JECS) Group.


A low-frequency IL4R locus variant in Japanese patients with intravenous immunoglobulin therapy-unresponsive Kawasaki disease
Pediatr Rheumatol Online J,17(1):34 2019(Jul. 03)
Author:Amano Y, Akazawa Y, Yasuda J, Yoshino K, Kojima K, Kobayashi N, Matsuzaki S, Nagasaki M, Kawai Y, Minegishi N, Ishida N, Motoki N, Hachiya A, Nakazawa Y, Yamamoto M, Koike K, Takeshita T.


Significance of Molecular Monitoring of T Cells for the Decision of Treatment Strategy for Epstein-Barr Virus-associated Hemophagocytic Lymphohistiocytosis
JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY,41(5):407-409 2019(Jul.)
Author:Saito, Takamasa; Tanaka, Miyuki; Matsuda, Kazuyuki; Honma, Hitoshi; Komori, Kazutoshi; Morita, Daisuke; Nakazawa, Hideyuki; Yanagisawa, Ryu; Nakazawa, Yozo;
Keywords:hemophagocytic lymphohistiocytosis; EB virus; T-cell clonality; immunochemotherapy;


Comparison of tacrolimus combined with methylprednisolone or methotrexate as graft-versus-host disease prophylaxis after umbilical cord blood transplantation
BONE MARROW TRANSPLANTATION,54:613-614 2019(Jul.)
Author:Shigemura, Tomonari; Sakashita, Kazuo; Okura, Eri; Morita, Daisuke; Komori, Kazutoshi; Kurata, Takashi; Hirabayashi, Koichi; Saito, Shoji; Tanaka, Miyuki; Yanagisawa, Ryu; Nakazawa, Yozo;


Significance of Molecular Monitoring of T Cells for the Decision of Treatment Strategy for Epstein-Barr Virus-associated Hemophagocytic Lymphohistiocytosis
J Pediatr Hematol Oncol,41(5):407-409 2019(Jul.)
Author:Saito T, Tanaka M, Matsuda K, Honma H, Komori K, Morita D, Nakazawa H, Yanagisawa R, Nakazawa Y.


DOCK8 mutation diagnosed using whole-exome sequencing of the dried blood spot-derived DNA: a case report of an Iraqi girl diagnosed in Japan
BMC Med Genet,20(1):114 2019(Jun. 26)
Author:Al-Kzayer LFY, Al-Aradi HMH, Shigemura T, Sano K, Tanaka M, Hamada M, Ali KH, Aldaghir OM, Nakazawa Y, Okuno Y.


Ovarian function after allogeneic hematopoietic stem cell transplantation in children and young adults given 8-Gy total body irradiation-based reduced-toxicity myeloablative conditioning
PEDIATRIC TRANSPLANTATION,23(3):e13372 2019(May)
Author:Komori, Kazutoshi; Hirabayashi, Koichi; Morita, Daisuke; Hara, Yosuke; Kurata, Takashi; Saito, Shoji; Tanaka, Miyuki; Yanagisawa, Ryu; Sakashita, Kazuo; Koike, Kenichi; Nakazawa, Yozo;
Keywords:8-Gy TBI; children; hematological malignancies; HSCT; POI;


Factors predicting the recurrence of Epstein-Barr virus-associated hemophagocytic lymphohistiocytosis in children after treatment using the HLH-2004 protocol
INTERNATIONAL JOURNAL OF HEMATOLOGY,109(5):612-617 2019(May)
Author:Yanagaisawa, Ryu; Matsuda, Kazuyuki; Ohga, Shouichi; Kanegane, Hirokazu; Morimoto, Akira; Okamoto, Yasuhiro; Ohara, Akira; Fukushima, Keitaro; Sotomatsu, Manabu; Nomura, Keiko; Saito, Akiko M.; Horibe, Keizo; Ishii, Eiichi; Nakazawa, Yozo;
Keywords:Hemophagocytic lymphohistiocytosis; EBV DNA; HLH-2004 protocol;


Factors predicting the recurrence of Epstein-Barr virus-associated hemophagocytic lymphohistiocytosis in children after treatment using the HLH-2004 protocol (vol 109, pg 612, 2019)
INTERNATIONAL JOURNAL OF HEMATOLOGY,109(5):629-629 2019(May)
Author:Yanagisawa, Ryu; Matsuda, Kazuyuki; Ohga, Shouichi; Kanegane, Hirokazu; Morimoto, Akira; Okamoto, Yasuhiro; Ohara, Akira; Fukushima, Keitaro; Sotomatsu, Manabu; Nomura, Keiko; Saito, Akiko M.; Horibe, Keizo; Ishii, Eiichi; Nakazawa, Yozo;


Correction to: Factors predicting the recurrence of Epstein-Barr virus-associated hemophagocytic lymphohistiocytosis in children after treatment using the HLH-2004 protocol
Int J Hematol,109(5):629 2019(May)
Author:Yanagisawa R, Matsuda K, Ohga S, Kanegane H, Morimoto A, Okamoto Y, Ohara A, Fukushima K, Sotomatsu M, Nomura K, Saito AM, Horibe K, Ishii E, Nakazawa Y.


Factors predicting the recurrence of Epstein-Barr virus-associated hemophagocytic lymphohistiocytosis in children after treatment using the HLH-2004 protocol
Int J Hematol,109(5):612-617 2019(May)
Author:Yanagaisawa R, Matsuda K, Ohga S, Kanegane H, Morimoto A, Okamoto Y, Ohara A, Fukushima K, Sotomatsu M, Nomura K, Saito AM, Horibe K, Ishii E, Nakazawa Y.


Ovarian function after allogeneic hematopoietic stem cell transplantation in children and young adults given 8-Gy total body irradiation-based reduced-toxicity myeloablative conditioning
Pediatr Transplant,23(3):e13372 2019(May)
Author:Komori K, Hirabayashi K, Morita D, Hara Y, Kurata T, Saito S, Tanaka M, Yanagisawa R, Sakashita K, Koike K, Nakazawa Y.


Neurocutaneous Melanosis in Association With Large Congenital Melanocytic Nevi in Children: A Report of 2 Cases With Clinical, Radiological, and Pathogenetic Evaluation
Front Neurol,10:79 2019(Feb. 07)
Author:Chen L, Zhai L, Al-Kzayer LFY, Sarsam SN, Liu T, Alzakar RH, Nakazawa Y.


Outcomes in children with hemophagocytic lymphohistiocytosis treated using HLH-2004 protocol in Japan
INTERNATIONAL JOURNAL OF HEMATOLOGY,109(2):206-213 2019(Feb.)
Author:Yanagisawa, Ryu; Nakazawa, Yozo; Matsuda, Kazuyuki; Yasumi, Takahiro; Kanegane, Hirokazu; Ohga, Shouichi; Morimoto, Akira; Hashii, Yoshiko; Imaizumi, Masue; Okamoto, Yasuhiro; Saito, Akiko M.; Horibe, Keizo; Ishii, Eiichi; HLH LCH Comm; Japan Children's Canc Grp;
Keywords:HSCT; HLH-2004; Epstein-Barr virus; FHL; EBV-HLH;


Outcomes in children with hemophagocytic lymphohistiocytosis treated using HLH-2004 protocol in Japan
Int J Hematol,109(2):206-213 2019(Feb.)
Author:Yanagisawa R, Nakazawa Y, Matsuda K, Yasumi T, Kanegane H, Ohga S, Morimoto A, Hashii Y, Imaizumi M, Okamoto Y, Saito AM, Horibe K, Ishii E; HLH/LCH committee members of the Japan Children’s Cancer Group.


A Syrian Refugee in Iraq Diagnosed as a Case of IL12RB1 Deficiency in Japan Using Dried Blood Spots
Front Immunol,10:58 2019(Jan. 25)
Author:Al-Kzayer LFY, Yassin AK, Salih KH, Shigemura T, Sano K, Al-Simaani RBY, Tanaka M, Nakazawa Y, Okuno Y.


Comparison of conditioning regimens for autologous stem cell transplantation in children with acute myeloid leukemia: A nationwide retrospective study in Japan
PEDIATRIC BLOOD & CANCER,66(1):e27459 2019(Jan.)
Author:Sakaguchi, Hirotoshi; Muramatsu, Hideki; Hasegawa, Daiichiro; Kudo, Kazuko; Ishida, Hiroyuki; Yoshida, Nao; Koh, Katsuyoshi; Noguchi, Maiko; Shiba, Norio; Tokimasa, Sadao; Fukuda, Takhiro; Goto, Hiroaki; Miyamura, Takako; Nakazawa, Yozo; Hashii, Yoshiko; Inoue, Masami; Atsuta, Yoshiko; Japan Soc Hematopoietic Cell Trans;
Keywords:acute myeloid leukemia; autologous bone marrow transplantation; autologous peripheral blood stem cell transplantation; myeloablative conditioning regimen;


Epstein-Barr Virus (EBV)-induced B-cell Lymphoproliferative Disorder Mimicking the Recurrence of EBV-associated Hemophagocytic Lymphohistiocytosis
JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY,41(1):E44-E46 2019(Jan.)
Author:Yatsushiro, Yuki; Nishikawa, Takuro; Saito, Aki; Nakazawa, Yozo; Imadome, Ken-Ichi; Nakagawa, Shunsuke; Kodama, Yuichi; Okamoto, Yasuhiro; Kanegane, Hirokazu; Kawano, Yoshifumi;
Keywords:Epstein-Barr virus; EBV-associated hemophagocytic lymphohistiocytosis; EBV-associated lymphoproliferative disorder; etoposide; rituximab;


Mosaicism of an ELANE Mutation in an Asymptomatic Mother
JOURNAL OF CLINICAL IMMUNOLOGY,39(1):106-111 2019(Jan.)
Author:Shigemura, Tomonari; Kobayashi, Norimoto; Agematsu, Kazunaga; Ohara, Osamu; Nakazawa, Yozo;
Keywords:Severe congenital neutropenia; ELANE gene; mosaicism; induced pluripotent stem cells; granulopoiesis;


Mosaicism of an ELANE Mutation in an Asymptomatic Mother
J Clin Immunol,39(1):106-111 2019(Jan.)
Author:Shigemura T, Kobayashi N, Agematsu K, Ohara O, Nakazawa Y.


Comparison of conditioning regimens for autologous stem cell transplantation in children with acute myeloid leukemia: A nationwide retrospective study in Japan
Pediatr Blood Cancer,66(1):e27459 2019(Jan.)
Author:Sakaguchi H, Muramatsu H, Hasegawa D, Kudo K, Ishida H, Yoshida N, Koh K, Noguchi M, Shiba N, Tokimasa S, Fukuda T, Goto H, Miyamura T, Nakazawa Y, Hashii Y, Inoue M, Atsuta Y; Pediatric AML Working Group of the Japan Society for Hematopoietic Cell Transplantation.


Epstein-Barr Virus (EBV)-induced B-cell Lymphoproliferative Disorder Mimicking the Recurrence of EBV-associated Hemophagocytic Lymphohistiocytosis
J Pediatr Hematol Oncol,41(1):e44-e46 2019(Jan.)
Author:Yatsushiro Y, Nishikawa T, Saito A, Nakazawa Y, Imadome KI, Nakagawa S, Kodama Y, Okamoto Y, Kanegane H, Kawano Y.


A Syrian Refugee in Iraq Diagnosed as a Case of IL12RB1 Deficiency in Japan Using Dried Blood Spots
FRONTIERS IN IMMUNOLOGY,10:58 2019
Author:Al-Kzayer, Lika'a Fasih Y.; Yassin, Ahmed K.; Salih, Khalid Hama; Shigemura, Tomonari; Sano, Kenji; Al-Simaani, Ruwaid Behnam Y.; Tanaka, Miyuki; Nakazawa, Yozo; Okuno, Yusuke;
Keywords:IL12RB1 deficiency; mendelian susceptibility to mycobacterial diseases (MSMD); Bacillus Calmette-Guerin (BCG); Flinders Technology Associates (FTA); tuberculosis (TB); non-tuberculous mycobacteria (NTM); whole exome sequencing (WES); Iraq;


Neurocutaneous Melanosis in Association With Large Congenital Melanocytic Nevi in Children: A Report of 2 Cases With Clinical, Radiological, and Pathogenetic Evaluation
FRONTIERS IN NEUROLOGY,10:79 2019
Author:Chen, Lei; Zhai, Liqin; Al-Kzayer, Lika'a Fasih Y.; Sarsam, Shamil Naji; Liu, Tingting; Alzakar, Riyadh H.; Nakazawa, Yozo;
Keywords:congenital melanocytic nevi (CMN); neurocutaneous melanosis (NCM); CNS melanoma; leptomeningeal melanoma; NRAS mutation; large-CMN; giant-CMN; BRAF V600E mutation;


Optimization of PiggyBac Transposon-Based Gene Delivery by the MaxCyte Scalable Transfection System for Manufacturing Chimeric Antigen Receptor-T Cells
MOLECULAR THERAPY,27(4):164-164 2019
Author:Tomida, Akimasa; Yagyu, Shigeki; Yamashima, Kumiko; Kubo, Hiroshi; Iehara, Tomoko; Nakazawa, Yozo; Hosoi, Hajime;


Evaluation of the Safety and Efficacy of piggyBac Transposon-Mediated Chimeric Antigen Receptor T Cells Using a Non-Human Primate Model
MOLECULAR THERAPY,27(4):408-408 2019
Author:Morokawa, Hirokazu; Tanaka, Miyuki; Saito, Shoji; Shimoi, Akihito; Yagyu, Shigeki; Nakazawa, Yozo;


DOCK8 mutation diagnosed using whole-exome sequencing of the dried blood spot-derived DNA: a case report of an Iraqi girl diagnosed in Japan
BMC MEDICAL GENETICS,20:114 2019
Author:Al-Kzayer, Lika'a Fasih Y.; Al-Aradi, Hanadi Munaf H.; Shigemura, Tomonari; Sano, Kenji; Tanaka, Miyuki; Hamada, Motoharu; Ali, Kenan Hussien; Aldaghir, Osamah Mohammed; Nakazawa, Yozo; Okuno, Yusuke;
Keywords:DOCK8 deficiency; Primary immune deficiency (PID); Dried blood spots; Flinders technology associates (FTA) cards; Whole exome sequencing (WES); Hyper immunoglobulin E syndrome (HIES); Lymphoproliferative disease (LPD); Consanguineous marriages; Iraq;


A low-frequency IL4R locus variant in Japanese patients with intravenous immunoglobulin therapy-unresponsive Kawasaki disease
PEDIATRIC RHEUMATOLOGY,17:34 2019
Author:Amano, Yuji; Akazawa, Yohei; Yasuda, Jun; Yoshino, Kazuhisa; Kojima, Katsuhiko; Kobayashi, Norimoto; Matsuzaki, Satoshi; Nagasaki, Masao; Kawai, Yosuke; Minegishi, Naoko; Ishida, Noriko; Motoki, Noriko; Hachiya, Akira; Nakazawa, Yozo; Yamamoto, Masayuki; Koike, Kenichi; Takeshita, Toshikazu;
Keywords:Kawasaki disease; Interleukin-4 receptor; IVIG-resistance; Single nucleotide variant;


Alcohol Consumption During Pregnancy and Risk of Placental Abnormality: The Japan Environment and Children's Study
SCIENTIFIC REPORTS,9:10259 2019
Author:Ohira, Satoshi; Motoki, Noriko; Shibazaki, Takumi; Misawa, Yuka; Inaba, Yuji; Kanai, Makoto; Kurita, Hiroshi; Shiozawa, Tanri; Nakazawa, Yozo; Tsukahara, Teruomi; Nomiyama, Tetsuo; Kawamoto, Toshihiro; Saito, Hirohisa; Kishi, Reiko; Yaegashi, Nobuo; Hashimoto, Koichi; Mori, Chisato; Ito, Shuichi; Yamagata, Zentaro; Inadera, Hidekuni; Kamijima, Michihiro; Nakayama, Takeo; Iso, Hiroyasu; Shima, Masayuki; Hirooka, Yasuaki; Suganuma, Narufumi; Kusuhara, Koichi; Katoh, Takahiko; Japan Environm Childrens Study JEC;


Maternal Exposure to Housing Renovation During Pregnancy and Risk of Offspring with Congenital Malformation: The Japan Environment and Children's Study
SCIENTIFIC REPORTS,9:11564 2019
Author:Motoki, Noriko; Inaba, Yuji; Shibazaki, Takumi; Misawa, Yuka; Ohira, Satoshi; Kanai, Makoto; Kurita, Hiroshi; Nakazawa, Yozo; Tsukahara, Teruomi; Nomiyama, Tetsuo; Kawamoto, Toshihiro; Saito, Hirohisa; Kishi, Reiko; Yaegashi, Nobuo; Hashimoto, Koichi; Mori, Chisato; Ito, Shuichi; Yamagata, Zentaro; Inadera, Hidekuni; Kamijima, Michihiro; Nakayama, Takeo; Iso, Hiroyasu; Shima, Masayuki; Hirooka, Yasuaki; Suganuma, Narufumi; Kusuhara, Koichi; Katoh, Takahiko; Japan Environm Childrens Study JEC;


Proton Beam Therapy for Adolescent Primary Central Nervous System Lymphoma With Residual Tumor After Intensive Chemotherapy: A Case Report
PRACTICAL RADIATION ONCOLOGY,9(5):333-337 2019
Author:Komori, Kazutoshi; Saito, Shoji; Araya, Masayuki; Morita, Daisuke; Kurata, Takashi; Hirabayashi, Koichi; Tanaka, Miyuki; Koiwai, Keiichiro; Tauchi, Katsunori; Masaki, Hidekazu; Nakazawa, Yozo;


NUDT15 Variants Confer High Incidence of Secondary Malignancies of ALL in Children
BLOOD,134 2019
Author:Yoshida, Masanori; Nakabayashi, Kazuhiko; Sato-Otsubo, Aiko; Tsujimoto, Shinichi; Yoshida, Kaoru; Shirai, Ryota; Osumi, Tomoo; Yuza, Yuki; Takagi, Masatoshi; Takahashi, Hiroyuki; Koh, Katsuyoshi; Kinoshita, Akitoshi; Hino, Moeko; Imamura, Toshihiko; Nakazawa, Yozo; Mayuko, Okuya; Kakuda, Harumi; Sanada, Masashi; Matsumoto, Kimikazu; Tomizawa, Daisuke; Kiyokawa, Nobutaka; Ohara, Akira; Manabe, Atsushi; Hata, Kenichiro; Yang, Jun J.; Kato, Motohiro;


CAR-T 療法の現状と今後の展望
信州医学雑誌,66(6):425-433 2018(Dec.)
Author:齋藤 章治, 中沢 洋三


Comparison of administration of platelet concentrates suspended in M-sol or BRS-A for pediatric patients
TRANSFUSION,58(12):2952-2958 2018(Dec.)
Author:Kojima, Shunsuke; Yanagisawa, Ryu; Tanaka, Miyuki; Nakazawa, Yozo; Shimodaira, Shigetaka;


Pediatric B Cell Lymphoma with an Indolent Clinical Course and Positive Streptococcal Test Results
PEDIATRIC BLOOD & CANCER,65:S91-S91 2018(Nov.)
Author:Kumagai, Satomi; Saito, Shoji; Tanaka, Miyuki; Okura, Eri; Natsume, Takenori; Morota, Haruka; Morita, Daisuke; Shigemura, Tomonari; Nakazawa, Yozo;


Cisplatin-induced nephrotoxicity in patients with advanced neuroblastoma
PEDIATRIC BLOOD & CANCER,65(9):e27253 2018(Sep.)
Author:Yanagisawa, Ryu; Kubota, Noriko; Hidaka, Eiko; Sakashita, Kazuo; Tanaka, Miyuki; Nakazawa, Yozo; Nakamura, Tomohiko;


Successful induction of therapeutic urinary concentration by intravenous ganciclovir and oral valganciclovir with remission of adenoviral hemorrhagic cystitis after cord blood transplantation
PEDIATRIC TRANSPLANTATION,22(6):e13241 2018(Sep.)
Author:Yanagisawa, Toshimitsu; Saito, Shoji; Katsuyama, Yoshihiko; Hirabayashi, Koichi; Shigemura, Tomonari; Tanaka, Miyuki; Sakashita, Kazuo; Nakazawa, Yozo;
Keywords:adenovirus type 11; ganciclovir; hematopoietic stem cell transplantation; hemorrhagic cystitis; pediatric; valganciclovir;


Severe acyclovir-resistant herpes simplex virus 1 infection following cord blood transplantation
INTERNATIONAL JOURNAL OF HEMATOLOGY,108(3):237-238 2018(Sep.)
Author:Shigemura, Tomonari; Nakazawa, Yozo; Yoshikawa, Tomoki; Fujii, Hikaru; Yamada, Souichi; Saijo, Masayuki; Okuyama, Ryuhei;
Keywords:Acyclovir-resistant herpes simplex virus 1; Skin lesion; Cord blood transplantation; Foscarnet;


Prevention of transfusion-transmitted CMV viremia using leukocyte-reduced blood products in seronegative UCBT patients
BONE MARROW TRANSPLANTATION,53:514-514 2018(Sep.)
Author:Shigemura, Tomonari; Kurata, Takashi; Komori, Kazutoshi; Morita, Daisuke; Tanaka, Miyuki; Sakashita, Kazuo; Nakazawa, Yozo;


Cisplatin-induced nephrotoxicity in patients with advanced neuroblastoma.
Pediatr Blood Cancer,65(9):e27253 2018(Sep.)
Author:Yanagisawa R, Kubota N, Hidaka E, Sakashita K, Tanaka M, Nakazawa Y, Nakamura T.


Postencephalitic epilepsy secondary to cytomegalovirus encephalitis
PEDIATRICS INTERNATIONAL,60(8):758-760 2018(Aug.)
Author:Nasuno, Masaru; Shigemura, Tomonari; Nakazawa, Yozo; Inaba, Yuji; Motobayashi, Mitsuo;
Keywords:cord blood transplantation; cytomegalovirus ventriculoencephalitis; postencephalitic epilepsy; severe combined immunodeficiency;


Integration Mapping of piggyBac-Mediated CD19 Chimeric Antigen Receptor T Cells Analyzed by Novel Tagmentation-Assisted PCR
EBIOMEDICINE,34:18-26 2018(Aug.)
Author:Hamada, Motoharu; Nishio, Nobuhiro; Okuno, Yusuke; Suzuki, Satoshi; Kawashima, Nozomu; Muramatsu, Hideki; Tsubota, Shoma; Wilson, Matthew H.; Morita, Daisuke; Kataoka, Shinsuke; Ichikawa, Daisuke; Murakami, Norihiro; Taniguchi, Rieko; Suzuki, Kyogo; Kojima, Daiei; Sekiya, Yuko; Nishikawa, Eri; Narita, Atsushi; Hama, Asahito; Kojima, Seiji; Nakazawa, Yozo; Takahashi, Yoshiyuki;
Keywords:CD19 CAR-T cell; piggyBac transposon; Integration site mapping; Tag-PCR;


Postencephalitic epilepsy secondary to cytomegalovirus encephalitis.
Pediatr Int,60(8):758-760 2018(Aug.)
Author:Nasuno M, Shigemura T, Nakazawa Y, Inaba Y, Motobayashi M.


Integration Mapping of piggyBac-Mediated CD19 Chimeric Antigen Receptor T Cells Analyzed by Novel Tagmentation-Assisted PCR.
EBioMedicine,34:18-26 2018(Aug.)
Author:Hamada M, Nishio N, Okuno Y, Suzuki S, Kawashima N, Muramatsu H, Tsubota S, Wilson MH, Morita D, Kataoka S, Ichikawa D, Murakami N, Taniguchi R, Suzuki K, Kojima D, Sekiya Y, Nishikawa E, Narita A, Hama A, Kojima S, Nakazawa Y, Takahashi Y.


An infant case of diffuse cerebrospinal lesions and cardiomyopathy caused by a BOLA3 mutation
BRAIN & DEVELOPMENT,40(6):484-488 2018(Jun.)
Author:Nishioka, Makoto; Inaba, Yuji; Motobayashi, Mitsuo; Hara, Yosuke; Numata, Ryusuke; Amano, Yoshiro; Shingu, Kunihiko; Yamamoto, Yoichiro; Murayama, Kei; Ohtake, Akira; Nakazawa, Yozo;
Keywords:BOLA3 gene; Cardiomyopathy; Encephalopathy; Magnetic resonance imaging; Mitochondrial respiratory chain complexes;


Childhood asymptomatic renal arteriovenous fistula 5 years after renal biopsy
PEDIATRICS INTERNATIONAL,60(6):601-602 2018(Jun.)
Author:Matsuoka, Daisuke; Hidaka, Yoshihiko; Kurozumi, Masahiro; Tsukahara, Yoshinori; Nakazawa, Yozo;
Keywords:arteriovenous fistula; doppler ultrasonography; embolization; renal biopsy;


Childhood asymptomatic renal arteriovenous fistula 5 years after renal biopsy.
Pediatr Int,60(6):601-602 2018(Jun.)
Author:Matsuoka D, Hidaka Y, Kurozumi M, Tsukahara Y, Nakazawa Y.


An infant case of diffuse cerebrospinal lesions and cardiomyopathy caused by a BOLA3 mutation.
Brain Dev,40(6):484-488 2018(Jun.)
Author:Nishioka M, Inaba Y, Motobayashi M, Hara Y, Numata R, Amano Y, Shingu K, Yamamoto Y, Murayama K, Ohtake A, Nakazawa Y.


Chimeric Antigen Receptor T Cells Redirecting EPHB4 for the Treatment of Human Rhabdomyosarcoma
MOLECULAR THERAPY,26(5):340-340 2018(May)
Author:Yagyu, Shigeki; Nakamura, Kayoko; Morita, Daisuke; Tanaka, Miyuki; Kikuchi, Ken; Iehara, Tomoko; Hosoi, Hajime; Nakazawa, Yozo;


PiggyBac Transposon-Mediated CAR-T Cells Targeting GM-CSF Receptors Prolong the Survival of Mice Bearing Human Acute Myeloid Leukemia
MOLECULAR THERAPY,26(5):194-195 2018(May)
Author:Hasegawa, Aiko; Narimatsu, Shogo; Tanaka, Miyuki; Nagai, Mika; Morita, Daisuke; Saito, Shoji; Nakano, Shigeru; Onozato, Tomoya; Hayashi, Morimichi; Matsuda, Kazuyuki; Yanagisawa, Ryu; Ohnota, Hideki; Nakazawa, Yozo;


Co-occurrence of hypertrophic cardiomyopathy and juvenile myelomonocytic leukemia in a neonate with Noonan syndrome, leading to premature death.
Clin Case Rep,6(7):1202-1207 2018(May)
Author:Tamura A, Uemura S, Matsubara K, Kozuki E, Tanaka T, Nino N, Yokoi T, Saito A, Ishida T, Hasegawa D, Umeki I, Niihori T, Nakazawa Y, Koike K, Aoki Y, Kosaka Y.


Myelodysplastic syndrome in an infant with constitutional pure duplication 1q41-qter.
Hum Genome Var,5:6 2018(May)
Author:Morokawa H, Kamiya M, Wakui K, Kobayashi M, Kurata T, Matsuda K, Kawamura R, Kanno H, Fukushima Y, Nakazawa Y, Kosho T.


Feasibility and Immune Response of WT1 Peptide Vaccination in Combination with OK-432 for Paediatric Solid Tumors
ANTICANCER RESEARCH,38(4):2227-2234 2018(Apr.)
Author:Hirabayashi, Koichi; Yanagisawa, Ryu; Saito, Shoji; Higuchi, Yumiko; Koya, Terutsugu; Sano, Kenji; Koido, Shigeo; Okamoto, Masato; Sugiyama, Haruo; Nakazawa, Yozo; Shimodaira, Shigetaka;
Keywords:Adjuvant; immunotherapy; pediatric cancer; T cell; Wilms' tumor 1;


Enhanced Expression of Anti-CD19 Chimeric Antigen Receptor in piggyBac Transposon-Engineered T Cells
MOLECULAR THERAPY-METHODS & CLINICAL DEVELOPMENT,8:131-140 2018(Mar.)
Author:Morita, Daisuke; Nishio, Nobuhiro; Saito, Shoji; Tanaka, Miyuki; Kawashima, Nozomu; Okuno, Yusuke; Suzuki, Satoshi; Matsuda, Kazuyuki; Maeda, Yasuhiro; Wilson, Matthew H.; Dotti, Gianpietro; Rooney, Cliona M.; Takahashi, Yoshiyuki; Nakazawa, Yozo;


A Pediatric Case of Relapsing-Remitting Multiple Sclerosis Onset following Varicella Zoster Ophthalmicus with Optic Neuritis.
Case Rep Pediatr,2018:6931206 2018(Mar.)
Author:Shiba N, Inaba Y, Motobayashi M, Nishioka M, Kawasaki Y, Noda S, Matsuura H, Kobayashi N, Matsuoka T, Nakamura A, Nakazawa Y.


A pediatric case with peripheral facial nerve palsy caused by a granulomatous lesion associated with cat scratch disease
BRAIN & DEVELOPMENT,40(2):159-162 2018(Feb.)
Author:Nakamura, Chizuko; Inaba, Yuji; Tsukahara, Keiko; Mochizuki, Mie; Sawanobori, Emi; Nakazawa, Yozo; Aoyama, Kouki;
Keywords:Bartonella henselae; Cat scratch disease; Facial nerve palsy; Magnetic resonance imaging; Minocycline;


A pediatric case with peripheral facial nerve palsy caused by a granulomatous lesion associated with cat scratch disease.
Brain Dev,40(2):159-162 2018(Feb.)
Author:Nakamura C, Inaba Y, Tsukahara K, Mochizuki M, Sawanobori E, Nakazawa Y, Aoyama K.


Bacteremia due to Moraxella osloensis: a case report and literature review.
Braz J Infect Dis,22(1):60-62 2018(Jan.)
Author:Maruyama Y, Shigemura T, Aoyama K, Nagano N, Nakazawa Y.


Regional evaluation of childhood acute lymphoblastic leukemia genetic susceptibility loci among Japanese.
Sci Rep,8(1):789 2018(Jan.)
Author:Urayama KY, Takagi M, Kawaguchi T, Matsuo K, Tanaka Y, Ayukawa Y, Arakawa Y, Hasegawa D, Yuza Y, Kaneko T, Noguchi Y, Taneyama Y, Ota S, Inukai T, Yanagimachi M, Keino D, Koike K, Toyama D, Nakazawa Y, Kurosawa H, Nakamura K, Moriwaki K, et al.


Bacteremia due to Moraxella osloensis: a case report and literature review
BRAZILIAN JOURNAL OF INFECTIOUS DISEASES,22(1):60-62 2018
Author:Maruyama, Yuta; Shigemura, Tomonari; Aoyama, Koki; Nagano, Noriyuki; Nakazawa, Yozo;
Keywords:Moraxella osloensis; Bacteremia; MALDI-TOF MS; 16S rRNA gene sequencing;


Asymmetrically enlarged parietal foramina in a rare case of Goldenhar syndrome with a possible etiopathogenesis
ONCOTARGET,9(2):2962-2968 2018
Author:Al-Kzayer, Lika'a Fasih Y.; Sarsam, Shamil Naji; Alhur, Nagham Younus; Liu, Tingting; Nakazawa, Yozo;
Keywords:Goldenhar syndrome; oculoauriculovertebral spectrum; enlarged parietal foramina; assisted reproductive technology embryo; depleted uranium (DU);


Regional evaluation of childhood acute lymphoblastic leukemia genetic susceptibility loci among Japanese
SCIENTIFIC REPORTS,8:789 2018
Author:Urayama, Kevin Y.; Takagi, Masatoshi; Kawaguchi, Takahisa; Matsuo, Keitaro; Tanaka, Yoichi; Ayukawa, Yoko; Arakawa, Yuki; Hasegawa, Daisuke; Yuza, Yuki; Kaneko, Takashi; Noguchi, Yasushi; Taneyama, Yuichi; Ota, Setsuo; Inukai, Takeshi; Yanagimachi, Masakatsu; Keino, Dai; Koike, Kazutoshi; Toyama, Daisuke; Nakazawa, Yozo; Kurosawa, Hidemitsu; Nakamura, Kozue; Moriwaki, Koichi; Goto, Hiroaki; Sekinaka, Yujin; Morita, Daisuke; Kato, Motohiro; Takita, Junko; Tanaka, Toshihiro; Inazawa, Johji; Koh, Katsuyoshi; Ishida, Yasushi; Ohara, Akira; Mizutani, Shuki; Matsuda, Fumihiko; Manabe, Atsushi;


Hematopoietic Stem-Cell Transplantation in Children with Refractory Acute Myeloid Leukemia
BLOOD,132 2018
Author:Okamoto, Yasuhiro; Kudo, Kazuko; Tabuchi, Ken; Tomizawa, Daisuke; Taga, Takashi; Goto, Hiroaki; Yabe, Hiromasa; Nakazawa, Yozo; Koh, Katsuyoshi; Ikegame, Kazuhiro; Yoshida, Nao; Uchida, Naoyuki; Watanabe, Kenichiro; Koga, Yuuki; Inoue, Masami; Kato, Koji; Atsuta, Yoshiko; Ishida, Hiroyuki;


Piggybac CD19 CAR T Cells Eradicate CNS Leukemia By Direct Delivery into Cerebral Ventricle of Xenograft Mice Model
BLOOD,132 2018
Author:Tanaka, Kuniaki; Kato, Itaru; Tanaka, Miyuki; Morita, Daisuke; Takahashi, Yoshiyuki; Nakahata, Tatsutoshi; Umeda, Katsutsugu; Hiramatsu, Hidefumi; Adachi, Souichi; Takita, Junko; Nakazawa, Yozo;


Clinical Feature and Genetic Alterations in Myeloid/Natural Killer (NK) Cell Precursor Acute Leukemia and Myeloid/NK Cell Acute Leukemia
BLOOD,132 2018
Author:Nishimura, Akira; Yokoyama, Kazuaki; Yamagishi, Chika; Naruto, Takuya; Morio, Tomohiro; Kanai, Akinori; Matsui, Hirotaka; Higuchi, Naoko; Takada, Akiko; Okuno, Haruna; Saito, Shoji; Karakawa, Shuhei; Kobayashi, Shogo; Sano, Hideki; Koike, Takashi; Hasegawa, Daisuke; Fujisaki, Hiroyuki; Hasegawa, Daiichiro; Koike, Kazutoshi; Ogawa, Atsushi; Kinoshita, Akitoshi; Shiba, Norio; Miki, Mizuka; Nakayama, Hideki; Nakazawa, Yozo; Imamura, Toshihiko; Taga, Takashi; Adachi, Souichi; Koh, Katsuyoshi; Manabe, Atsushi; Taki, Tomohiko; Ishida, Yasushi; Tojo, Arinobu; Takagi, Masatoshi;


Hematopoietic Stem Cell Transplantation in Children with Refractory Acute Lymphoblastic Leukemia
BLOOD,132 2018
Author:Okamoto, Yasuhiro; Nakazawa, Yozo; Inoue, Masami; Watanabe, Kenichiro; Goto, Hiroaki; Yoshida, Nao; Noguchi, Maiko; Kikuta, Atsushi; Kato, Koji; Hashii, Yoshiko; Atsuta, Yoshiko; Kato, Motohiro;


Successful induction of therapeutic urinary concentration by intravenous ganciclovir and oral valganciclovir with remission of adenoviral hemorrhagic cystitis after cord blood transplantation.
Pediatr Transplant,:e13241 2018
Author:Yanagisawa T, Saito S, Katsuyama Y, Hirabayashi K, Shigemura T, Tanaka M, Sakashita K, Nakazawa Y.


Severe acyclovir-resistant herpes simplex virus 1 infection following cord blood transplantation.
Int J Hematol,:in press 2018
Author:Shigemura T, Nakazawa Y, Yoshikawa T, Fujii H, Yamada S, Saijo M, Okuyama R.


Asymmetrically enlarged parietal foramina in a rare case of Goldenhar syndrome with a possible etiopathogenesis.
Oncotarget,9(2):2962-2968 2017(Dec.)
Author:Al-Kzayer LFY, Sarsam SN, Alhur NY, Liu T, Nakazawa Y.


Enhanced Expression of Anti-CD19 Chimeric Antigen Receptor in piggyBac Transposon-Engineered T Cells.
Mol Ther Methods Clin Dev,8:131-140 2017(Dec.)
Author:Morita D, Nishio N, Saito S, Tanaka M, Kawashima N, Okuno Y, Suzuki S, Matsuda K, Maeda Y, Wilson MH, Dotti G, Rooney CM, Takahashi Y, Nakazawa Y.


Outcome of Children with Hemophagocytic Lymphohistiocytosis with HLH-2004 Protocol in Japan
PEDIATRIC BLOOD & CANCER,64:S42-S43 2017(Nov.)
Author:Yanagisawa, Ryu; Nakazawa, Yozo; Matsuda, Kazuyuki; Yasumi, Takahiro; Kanegane, Hirokazu; Ohga, Shouichi; Morimoto, Akira; Saito, Akiko M.; Horibe, Keizo; Ishii, Eiichi; HLH LCH Comm Members Japan;


Acute Myeloid Leukemia in a Patient With X-linked Severe Combined Immunodeficiency
JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY,39(8):E470-E472 2017(Nov.)
Author:Shigemura, Tomonari; Motobayashi, Mitsuo; Matsuda, Kazuyuki; Shimodaira, Takahiro; Kurata, Takashi; Kobayashi, Norimoto; Agematsu, Kazunaga; Nakazawa, Yozo;
Keywords:severe combined immunodeficiency; acute myeloid leukemia; cord blood transplantation; loss of heterozygosity; NRAS mutation; 6q deletion;


GM-CSF Receptor-targeted CAR T Cells for Myeloid Neoplasms
PEDIATRIC BLOOD & CANCER,64:S3-S3 2017(Nov.)
Author:Nakazawa, Yozo;


Chimeric Antigen Receptor T Cells Redirecting EPHB4 for the Treatment of Human Rhabdomyosarcoma
PEDIATRIC BLOOD & CANCER,64:S21-S22 2017(Nov.)
Author:Yagyu, Shigeki; Nakamura, Kayoko; Morita, Daisuke; Tanaka, Miyuki; Kikuchi, Ken; Iehara, Tomoko; Nakazawa, Yozo; Hosoi, Hajime;


Treatment Outcomes and Prognostic Factors after Allogeneic-HSCT for Patients with Low and Intermediate Risk in JPLSG AML-05 study
PEDIATRIC BLOOD & CANCER,64:S19-S19 2017(Nov.)
Author:Hashii, Yoshiko; Hyakuna, Nobuyuki; Ishida, Hiroyuki; Umeda, Katsutsugu; Takahashi, Yoshiyuki; Nagasawa, Masayuki; Yabe, Hiromasa; Nakazawa, Yozo; Fujisaki, Hiroyuki; Yano, Michihiro; Matsumoto, Kimikazu; Goto, Hiroaki; Kakuda, Harumi; Koh, Katsuyoshi; Tomizawa, Daisuke; Tawa, Akio; Taga, Takashi; Adachi, Souichi; Kato, Koji;


Retrospective Analysis of High Risk Childhood AML Undergoing Allo-SCT in First CR: Results of AML-05 by JPLSG
PEDIATRIC BLOOD & CANCER,64:S68-S68 2017(Nov.)
Author:Hyakuna, Nobuyuki; Hashii, Yoshiko; Ishida, Hiroyuki; Umeda, Katsutsugu; Takahashi, Yoshiyuki; Nagasawa, Masayuki; Yabe, Hiromasa; Nakazawa, Yozo; Koh, Katsuyoshi; Goto, Hiroaki; Fujisaki, Hiroyuki; Matsumoto, Kimikazu; Kakuda, Harumi; Yano, Michihiro; Tawa, Akio; Tomizawa, Daisuke; Taga, Takashi; Adachi, Souichi; Kato, Koji;


Monitoring Epstein-Barr Virus DNA in T Cell Lineage and TCR Gene Clonality: A Case of Recurrent EBV-HLH
PEDIATRIC BLOOD & CANCER,64:S111-S112 2017(Nov.)
Author:Saito, Takamasa; Tanaka, Miyuki; Komori, Kazutoshi; Morita, Daisuke; Hirabayashi, Kouichi; Nakazawa, Yozo;


Infantile Myelodysplastic Syndrome Associated with Pure Partial Trisomy 1q Syndrome
PEDIATRIC BLOOD & CANCER,64:S110-S111 2017(Nov.)
Author:Morokawa, Hirokazu; Kamiya, Motoko; Komori, Kazutoshi; Morita, Daisuke; Kurata, Takashi; Tanaka, Miyuki; Kosho, Tomoki; Nakazawa, Yozo;


Acute Myeloid Leukemia in a Patient With X-linked Severe Combined Immunodeficiency.
J Pediatr Hematol Oncol,39(8):e470-e472 2017(Nov.)
Author:Shigemura T, Motobayashi M, Matsuda K, Shimodaira T, Kurata T, Kobayashi N, Agematsu K, Nakazawa Y.


Clinical features of a female with WDR45 mutation complicated by infantile spasms: a case report and literature review
BRAIN & DEVELOPMENT,39(9):804-807 2017(Oct.)
Author:Morikawa, Manami; Takano, Kyoko; Motobayashi, Mitsuo; Shiba, Naoko; Kosho, Tomoki; Nakazawa, Yozo; Inaba, Yuji;
Keywords:Beta-propeller protein-associated neurodegeneration; WDR45; Infantile spasms; West syndrome; Adrenocorticotropic hormone therapy;


Clinical features of a female with WDR45 mutation complicated by infantile spasms: a case report and literature review.
Brain Dev,39(9):804-807 2017(Oct.)
Author:Morikawa M, Takano K, Motobayashi M, Shiba N, Kosho T, Nakazawa Y, Inaba Y.


Efficacy and safety of anagrelide in childhood essential thrombocythemia
PEDIATRICS INTERNATIONAL,59(9):1017-1018 2017(Sep.)
Author:Kanai, Ayako; Morokawa, Hirokazu; Matsuda, Kazuyuki; Shimazaki, Ei; Nakazawa, Yozo;
Keywords:anagrelide; child; essential thrombocythemia;


Subclinical Neuroaxonal Damage in Patients With Clinically Mild Encephalitis/Encephalopathy With a Reversible Splenial Lesion.
Pediatr Neurol,74:e3-e4 2017(Sep.)
Author:Motobayashi M, Fukuyama T, Okuno-Yuguchi J, Tsukahara K, Nagaharu S, Hagimoto R, Kinoshita T, Nakazawa Y, Inaba Y.


Efficacy and safety of anagrelide in childhood essential thrombocythemia.
Pediatr Int,59(9):1017-1018 2017(Sep.)
Author:Kanai A, Morokawa H, Matsuda K, Shimazaki E, Nakazawa Y.


A case of GATA2-related myelodysplastic syndrome with unbalanced translocation der(1;7)(q10;p10)
PEDIATRIC BLOOD & CANCER,64(8):e26419 2017(Aug.)
Author:Kurata, Takashi; Shigemura, Tomonari; Muramatsu, Hideki; Okuno, Yusuke; Nakazawa, Yozo;
Keywords:der(1; 7); GATA2; myelodisplastic syndrome;


A case of GATA2-related myelodysplastic syndrome with unbalanced translocation der(1;7)(q10;p10).
Pediatr Blood Cancer,64(8) 2017(Aug.)
Author:Kurata T, Shigemura T, Muramatsu H, Okuno Y, Nakazawa Y.


Abnormal hematopoiesis and autoimmunity in human subjects with germline IKZF1 mutations
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY,140(1):223-231 2017(Jul.)
Author:Hoshino, Akihiro; Okada, Satoshi; Yoshida, Kenichi; Nishida, Naonori; Okuno, Yusuke; Ueno, Hiroo; Yamashita, Motoi; Okano, Tsubasa; Tsumura, Miyuki; Nishimura, Shiho; Sakata, Sonoko; Kobayashi, Masao; Nakamura, Haruna; Kamizono, Junji; Mitsui-Sekinaka, Kanako; Ichimura, Takuya; Ohga, Shouichi; Nakazawa, Yozo; Takagi, Masatoshi; Imai, Kohsuke; Shiraishi, Yuichi; Chiba, Kenichi; Tanaka, Hiroko; Miyano, Satoru; Ogawa, Seishi; Kojima, Seiji; Nonoyama, Shigeaki; Morio, Tomohiro; Kanegane, Hirokazu;
Keywords:Acute lymphoblastic leukemia; autoimmune disease; B-cell deficiency; common lymphoid progenitor; DNA binding; dysgammaglobulinemia; germline mutation; Ikaros; IKZF1; nuclear localization;


Recurrent MYB rearrangement in blastic plasmacytoid dendritic cell neoplasm.
Leukemia,31(7):1629-1633 2017(Jul.)
Author:Suzuki K, Suzuki Y, Hama A, Muramatsu H, Nakatochi M, Gunji M, Ichikawa D, Hamada M, Taniguchi R, Kataoka S, Murakami N, Kojima D, Sekiya Y, Nishikawa E, Kawashima N, Narita A, Nishio N, Nakazawa Y, Iwafuchi H, Watanabe KI, Takahashi Y, Ito M, et al.


Abnormal hematopoiesis and autoimmunity in human subjects with germline IKZF1 mutations.
J Allergy Clin Immunol,140(1):223-231 2017(Jul.)
Author:Hoshino A, Okada S, Yoshida K, Nishida N, Okuno Y, Ueno H, Yamashita M, Okano T, Tsumura M, Nishimura S, Sakata S, Kobayashi M, Nakamura H, Kamizono J, Mitsui-Sekinaka K, Ichimura T, Ohga S, Nakazawa Y, Takagi M, Imai K, Shiraishi Y, Chiba K, et al.


PiggyBac Mediated T Cells Expressing Anti CD19 Chimeric Antigen Receptor for a Clinical Trial
MOLECULAR THERAPY,25(5):291-291 2017(May)
Author:Nishio, Nobuhiro; Nakazawa, Yozo; Hamada, Motoharu; Suzuki, Satoshi; Tanaka, Miyuki; Morita, Daisuke; Kawashima, Nozomu; Okuno, Yusuke; Narita, Atsushi; Hama, Asahito; Muramatsu, Hideki; Muramatsu, Hideki; Kojima, Seiji; Takahashi, Yoshiyuki;


Increasing Risk of Disturbed Root Development in Permanent Teeth in Childhood Cancer Survivors Undergoing Cancer Treatment at Older Age
JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY,39(3):E150-E154 2017(Apr.)
Author:Tanaka, Miyuki; Kamata, Takahiro; Yanagisawa, Ryu; Morita, Daisuke; Saito, Shoji; Sakashita, Kazuo; Shiohara, Masaaki; Kurita, Hiroshi; Koike, Kenichi; Nakazawa, Yozo;
Keywords:odontogenesis; dental abnormalities; root formation; cancer treatment; childhood cancer survivors;


Analysis of Serum Cytokine Profiles in Childhood-Onset Ocular Myasthenia Gravis.
Pediatr Neurol,69:e3-e4 2017(Apr.)
Author:Motobayashi M, Nishimura T, Nakazawa Y, Inaba Y.


Increasing Risk of Disturbed Root Development in Permanent Teeth in Childhood Cancer Survivors Undergoing Cancer Treatment at Older Age.
J Pediatr Hematol Oncol,39(3):e150-e154 2017(Apr.)
Author:Tanaka M, Kamata T, Yanagisawa R, Morita D, Saito S, Sakashita K, Shiohara M, Kurita H, Koike K, Nakazawa Y.


Mediastinal lesions across the age spectrum: a clinicopathological comparison between pediatric and adult patients.
Oncotarget,8(35):59845-59853 2017(Apr.)
Author:Liu T, Al-Kzayer LFY, Xie X, Fan H, Sarsam SN, Nakazawa Y, Chen L.


Dramatic Reduction in Tumor Size During 5 Months of Pazopanib Therapy in Combination With Ifosfamide, Carboplatin, and Etoposide in an Early Infant With Progressive Soft Tissue Sarcoma
JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY,39(2):154-156 2017(Mar.)
Author:Watanabe, Tatsuo; Kurata, Takashi; Sano, Kenji; Suzuki, Shigeru; Kaneko, Tomoki; Motobayashi, Mitsuo; Shigemura, Tomonari; Sumi, Takuro; Koike, Kenichi; Nakazawa, Yozo;


Pediatric intestinal Beh double dagger et disease complicated by myeloid malignancies
INTERNATIONAL JOURNAL OF HEMATOLOGY,105(3):377-382 2017(Mar.)
Author:Kanamitsu, Kiichiro; Shimada, Akira; Nishiuchi, Ritsuo; Shigemura, Tomonari; Nakazawa, Yozo; Koike, Kenichi; Kodama, Yuichi; Shinkoda, Yuichi; Kawano, Yoshifumi; Yasui, Kozo; Sasaki, Koji; Kajiwara, Ryosuke; Tsukahara, Hirokazu; Manabe, Atsushi;
Keywords:Pediatric-onset Behcet disease; Myeloid malignancies; Gastrointestinal involvements;


Aberrant methylation of protocadherin 17 and its prognostic value in pediatric acute lymphoblastic leukemia
PEDIATRIC BLOOD & CANCER,64(3):e26259 2017(Mar.)
Author:Le Thanh Nha Uyen; Sakashita, Kazuo; Al-Kzayer, Lika'a Fasih Y.; Nakazawa, Yozo; Kurata, Takashi; Koike, Kenichi;
Keywords:BCP ALL; DNA methylation; PCDH17; prognostic factors; relapse;


Dramatic Reduction in Tumor Size During 5 Months of Pazopanib Therapy in Combination With Ifosfamide, Carboplatin, and Etoposide in an Early Infant With Progressive Soft Tissue Sarcoma.
J Pediatr Hematol Oncol,39(2):154-156 2017(Mar.)
Author:Watanabe T, Kurata T, Sano K, Suzuki S, Kaneko T, Motobayashi M, Shigemura T, Sumi T, Koike K, Nakazawa Y.


Pediatric intestinal Behçet disease complicated by myeloid malignancies.
Int J Hematol,105(3):377-382 2017(Mar.)
Author:Kanamitsu K, Shimada A, Nishiuchi R, Shigemura T, Nakazawa Y, Koike K, Kodama Y, Shinkoda Y, Kawano Y, Yasui K, Sasaki K, Kajiwara R, Tsukahara H, Manabe A.


Aberrant methylation of protocadherin 17 and its prognostic value in pediatric acute lymphoblastic leukemia
Pediatr Blood Cancer,64(3):e26259 2017(Mar.)
Author:Uyen TN, Sakashita K, Al-Kzayer LF, et al.


IFR4/MUM1-positive lymphoma in Waldeyer ring with co-expression of CD5 and CD10
PEDIATRIC BLOOD & CANCER,64(2):311-314 2017(Feb.)
Author:Chen, Lei; Al-Kzayer, Lika'a Fasih Y.; Liu, Tingting; Kobayashi, Norimoto; Nakazawa, Yozo; Koike, Kenichi;
Keywords:CD5; IRF4/MUM1-positive lymphoma; pediatric follicular lymphoma; Waldeyer ring;


Nonocclusive Mesenteric Ischemia after Chemotherapy in an Adolescent Patient with a History of Three Allogeneic Hematopoietic Stem Cell Transplantations for Acute Lymphoblastic Leukemia
PEDIATRICS AND NEONATOLOGY,58(1):81-84 2017(Feb.)
Author:Hirabayashi, Koichi; Takatsuki, Mitsuho; Motobayashi, Mitsuo; Kurata, Takashi; Saito, Shoji; Shigemura, Tomonari; Nakazawa, Yozo; Sakashita, Kazuo; Ishizone, Satoshi; Ota, Hiroyoshi; Koike, Kenichi;
Keywords:acute lymphoblastic leukemia; adolescent; allogeneic hematopoietic stem cell transplantation; chemotherapy; nonocclusive mesenteric ischemia;


Nonocclusive Mesenteric Ischemia after Chemotherapy in an Adolescent Patient with a History of Three Allogeneic Hematopoietic Stem Cell Transplantations for Acute Lymphoblastic Leukemia.
Pediatr Neonatol,58(1):81-84 2017(Feb.)
Author:Hirabayashi K, Takatsuki M, Motobayashi M, Kurata T, Saito S, Shigemura T, Nakazawa Y, Sakashita K, Ishizone S, Ota H, Koike K.


IFR4/MUM1-positive lymphoma in Waldeyer ring with co-expression of CD5 and CD10.
Pediatr Blood Cancer,64(2):311-314 2017(Feb.)
Author:Chen L, Al-Kzayer LF, Liu T, Kobayashi N, Nakazawa Y, Koike K.


Hematopoietic Stem Cell Transplantation for XIAP Deficiency in Japan
JOURNAL OF CLINICAL IMMUNOLOGY,37(1):85-91 2017(Jan.)
Author:Ono, Shintaro; Okano, Tsubasa; Hoshino, Akihiro; Yanagimachi, Masakatsu; Hamamoto, Kazuko; Nakazawa, Yozo; Imamura, Toshihiko; Onuma, Masaei; Niizuma, Hidetaka; Sasahara, Yoji; Tsujimoto, Hiroshi; Wada, Taizo; Kunisaki, Reiko; Takagi, Masatoshi; Imai, Kohsuke; Morio, Tomohiro; Kanegane, Hirokazu;
Keywords:Hematopoietic stem cell transplantation; hemophagocytic lymphohistiocytosis; inflammatory bowel disease; reduced intensity conditioning; XIAP deficiency; X-linked lymphoproliferative syndrome;


Hematopoietic Stem Cell Transplantation for XIAP Deficiency in Japan.
J Clin Immunol,37(1):85-91 2017(Jan.)
Author:Ono S, Okano T, Hoshino A, Yanagimachi M, Hamamoto K, Nakazawa Y, Imamura T, Onuma M, Niizuma H, Sasahara Y, Tsujimoto H, Wada T, Kunisaki R, Takagi M, Imai K, Morio T, Kanegane H.


Development of Frankfurter Sausage Manufacturing Using Emu Meat
JOURNAL OF THE JAPANESE SOCIETY FOR FOOD SCIENCE AND TECHNOLOGY-NIPPON SHOKUHIN KAGAKU KOGAKU KAISHI,64(9):476-482 2017
Author:Nakazawa, Yozo; Saka, Naonori; Yamazaki, Masao; Sato, Hiroaki;
Keywords:emu; frankfurter; sausage; physical property; coloration;


Mediastinal lesions across the age spectrum: a clinicopathological comparison between pediatric and adult patients
ONCOTARGET,8(35):59845-59853 2017
Author:Liu, Tingting; Al-Kzayer, Lika'a Fasih Y.; Xie, Xiao; Fan, Hua; Sarsam, Shamil Naji; Nakazawa, Yozo; Chen, Lei;
Keywords:mediastinal lesions; age distribution; histopathological distribution; the mediastinum;


Aberrant methylation of protocadherin 17 and its prognostic value in pediatric acute lymphoblastic leukemia.
Pediatr Blood Cancer,64(3) 2017
Author:Uyen TN, Sakashita K, Al-Kzayer LF, Nakazawa Y, Kurata T, Koike K.


Gangrenous appendicitis in a patient with severe congenital neutropenia
PEDIATRICS INTERNATIONAL,58(10):1093-1094 2016(Oct.)
Author:Shigemura, Tomonari; Ohno, Yasunari; Sano, Kenji; Uehara, Takeshi; Terada, Masaru; Koike, Kenichi; Nakazawa, Yozo;


Hemophagocytic lymphohistiocytosis: Pathogenesis, diagnosis, and management
PEDIATRICS INTERNATIONAL,58(9):817-825 2016(Sep.)
Author:Morimoto, Akira; Nakazawa, Yozo; Ishii, Eiichi;
Keywords:beta 2-microglobulin; cytotoxic T lymphocyte; Epstein-Barr virus; Ferritin; perforin;


Early-onset colorectal cancer in young adult survivors of childhood cancer
PEDIATRICS INTERNATIONAL,58(7):637-639 2016(Jul.)
Author:Morita, Daisuke; Nakazawa, Yozo; Tanaka, Miyuki; Nakayama, Yoshiko; Koizumi, Tomonobu; Koike, Kenichi;
Keywords:abdominal irradiation; childhood cancer survivor; colorectal cancer; long-term follow-up guideline; secondary cancer;


Early-onset colorectal cancer in young adult survivors of childhood cancer
PEDIATRICS INTERNATIONAL,58(7):637-639 2016(Jul.)
Author:Morita, Daisuke; Nakazawa, Yozo; Tanaka, Miyuki; Nakayama, Yoshiko; Koizumi, Tomonobu; Koike, Kenichi;


Enhancement of CAR Expression of piggyBac Transposon-Engineered T Cells by Stimulation with Viral Antigens
MOLECULAR THERAPY,24:S278-S279 2016(May)
Author:Morita, Daisuke; Tanaka, Miyuki; Nishio, Nobuhiro; Kawashima, Nozomu; Okuno, Yusuke; Wilson, Matthew H.; Rooney, Cliona M.; Takahashi, Yoshiyuki; Nakazawa, Yozo;


Clinical and Laboratory Outcomes After Umbilical Cord Blood Transplantation in a Patient with Mucolipidosis II Alpha/Beta
AMERICAN JOURNAL OF MEDICAL GENETICS PART A,170(5):1278-1282 2016(May)
Author:Shibazaki, Takumi; Hirabayashi, Koichi; Saito, Shoji; Shigemura, Tomonari; Nakazawa, Yozo; Sakashita, Kazuo; Takagi, Mineo; Shiohara, Masaaki; Adachi, Kaori; Nanba, Eiji; Sakai, Norio; Koike, Kenichi;


Immune Complex-Mediated Glomerulonephritis in a Patient with Wiskott-Aldrich Syndrome
JOURNAL OF CLINICAL IMMUNOLOGY,36(4):357-359 2016(May)
Author:Shigemura, Tomonari; Nakazawa, Yozo; Shimojo, Hisashi; Kobayashi, Norimoto; Agematsu, Kazunaga;


Loss of Mismatched HLA on the Leukemic Blasts of Patients With Relapsed Lymphoid Malignancies Following Bone Marrow Transplantation From Related Donors With HLA Class II Mismatches in the Graft Versus Host Direction
PEDIATRIC BLOOD & CANCER,63(4):709-711 2016(Apr.)
Author:Hirabayashi, Koichi; Kurata, Takashi; Horiuchi, Kazuki; Saito, Shoji; Shigemura, Tomonari; Tanaka, Miyuki; Yanagisawa, Ryu; Matsuda, Kazuyuki; Sakashita, Kazuo; Koike, Kenichi; Nakazawa, Yozo;


Anaplastic Large-Cell Lymphoma of the Left Ventricle Presenting With Arrhythmia and Cerebral Infarction due to Cardiogenic Embolism
PEDIATRIC BLOOD & CANCER,63(4):755-756 2016(Apr.)
Author:Hirabayashi, Koichi; Yamauchi, Shoko; Matsuzaki, Satoshi; Komatsu, Kazunori; Sano, Kenji; Koike, Kenichi; Nakazawa, Yozo;


Early detection of Rhizopus DNA in the serum of a patient with rhino-orbital-cerebral mucormycosis following allogeneic hematopoietic stem cell transplantation
INTERNATIONAL JOURNAL OF HEMATOLOGY,103(3):354-355 2016(Mar.)
Author:Shigemura, Tomonari; Nishina, Sayaka; Nakazawa, Hideyuki; Matsuda, Kazuyuki; Yaguchi, Takashi; Nakazawa, Yozo;


Intrathecal donor lymphocyte infusion for isolated leukemia relapse in the central nervous system following allogeneic stem cell transplantation: a case report and literature review
INTERNATIONAL JOURNAL OF HEMATOLOGY,103(1):107-111 2016(Jan.)
Author:Yanagisawa, Ryu; Nakazawa, Yozo; Sakashita, Kazuo; Saito, Shoji; Tanaka, Miyuki; Shiohara, Masaaki; Shimodaira, Shigetaka; Koike, Kenichi;


Improved Outcome of Unrelated Cord Blood Transplantation in Children with Severe Aplastic Anemia
BLOOD,128(22) 2016
Author:Kudo, Kazuko; Muramatsu, Hideki; Yoshida, Nao; Kobayashi, Ryoji; Yabe, Hiromasa; Endo, Mikiya; Inoue, Masami; Nakazawa, Yozo; Hara, Jun-ichi; Kaminami, Shinji; Inagaki, Jiro; Hashii, Yoshiko; Kato, Koji; Tabuchi, Ken; Kojima, Seiji;


Human CalDAG-GEFI deficiency increases bleeding and delays alpha IIb beta 3 activation
BLOOD,128(23):2729-2733 2016
Author:Kato, Hisashi; Nakazawa, Yozo; Kurokawa, Yumi; Kashiwagi, Hirokazu; Morikawa, Yoichiro; Morita, Daisuke; Banno, Fumiaki; Honda, Shigenori; Kanakura, Yuzuru; Tomiyama, Yoshiaki;


Anti-proliferative effects of T cells expressing a ligand-based chimeric antigen receptor against CD116 on CD34(+) cells of juvenile myelomonocytic leukemia
JOURNAL OF HEMATOLOGY & ONCOLOGY,9 2016
Author:Nakazawa, Yozo; Matsuda, Kazuyuki; Kurata, Takashi; Sueki, Akane; Tanaka, Miyuki; Sakashita, Kazuo; Imai, Chihaya; Wilson, Matthew H.; Koike, Kenichi;


Cytomegalovirus Encephalitis in a Patient with Severe Combined Immunodeficiency
JOURNAL OF CLINICAL IMMUNOLOGY,35(8):689-691 2015(Nov.)
Author:Motobayashi, Mitsuo; Shigemura, Tomonari; Tanaka, Miyuki; Kurata, Takashi; Kobayashi, Norimoto; Agematsu, Kazunaga; Amano, Yoshiro; Inaba, Yuji; Koike, Kenichi; Nakazawa, Yozo;


GATA2 and secondary mutations in familial myelodysplastic syndromes and pediatric myeloid malignancies
HAEMATOLOGICA,100(10):E398-E401 2015(Oct.)
Author:Wang, Xinan; Muramatsu, Hideki; Okuno, Yusuke; Sakaguchi, Hirotoshi; Yoshida, Kenichi; Kawashima, Nozomu; Xu, Yinyan; Shiraishi, Yuichi; Chiba, Kenichi; Tanaka, Hiroko; Saito, Shoji; Nakazawa, Yozo; Masunari, Taro; Hirose, Tadashi; Elmahdi, Shaimaa; Narita, Atsushi; Doisaki, Sayoko; Ismael, Olfat; Makishima, Hideki; Hama, Asahito; Miyano, Satoru; Takahashi, Yoshiyuki; Ogawa, Seishi; Kojima, Seiji;


Reduction in peripheral regulatory T cell population in childhood ocular type myasthenia gravis
BRAIN & DEVELOPMENT,37(8):808-816 2015(Sep.)
Author:Nishimura, Takafumi; Inaba, Yuji; Nakazawa, Yozo; Omata, Taku; Akasaka, Manami; Shirai, Ikuko; Ichikawa, Motoki;


SIGNIFICANCE OF MOLECULAR MONITORING IN CHILDREN WITH EPSTEIN-BARR VIRUS-ASSOCIATED HEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS
PEDIATRIC BLOOD & CANCER,62:S17-S17 2015(May)
Author:Yanagisawa, Ryu; Nakazawa, Yozo; Matsuda, Kazuyuki; Morimoto, Akira; Ishii, Eiichi; Japan Pediat Leukemia Lymphoma;


An Increase in Circulating B Cell-Activating Factor in Childhood-Onset Ocular Myasthenia Gravis
PEDIATRIC NEUROLOGY,52(4):404-409 2015(Apr.)
Author:Motobayashi, Mitsuo; Inaba, Yuji; Nishimura, Takafumi; Kobayashi, Norimoto; Nakazawa, Yozo; Koike, Kenichi;


Safety and tolerability of allogeneic dendritic cell vaccination with induction of Wilms tumor 1-specific T cells in a pediatric donor and pediatric patient with relapsed leukemia: a case report and review of the literature
CYTOTHERAPY,17(3):330-335 2015(Mar.)
Author:Saito, Shoji; Yanagisawa, Ryu; Yoshikawa, Kentaro; Higuchi, Yumiko; Koya, Terutsugu; Yoshizawa, Kiyoshi; Tanaka, Miyuki; Sakashita, Kazuo; Kobayashi, Takashi; Kurata, Takashi; Hirabayashi, Koichi; Nakazawa, Yozo; Shiohara, Masaaki; Yonemitsu, Yoshikazu; Okamoto, Masato; Sugiyama, Haruo; Koike, Kenichi; Shimodaira, Shigetaka;


Successful treatment for West syndrome with severe combined immunodeficiency
BRAIN & DEVELOPMENT,37(1):140-144 2015(Jan.)
Author:Motobayashi, Mitsuo; Inaba, Yuji; Fukuyama, Tetsuhiro; Kurata, Takashi; Niimi, Taemi; Saito, Shoji; Shiba, Naoko; Nishimura, Takafumi; Shigemura, Tomonari; Nakazawa, Yozo; Kobayashi, Norimoto; Sakashita, Kazuo; Agematsu, Kazunaga; Ichikawa, Motoki; Koike, Kenichi;


Dramatic Improvement in the Multifocal Positron Emission Tomography Findings of a Young Adult with Chronic Granulomatous Disease Following Allogeneic Hematopoietic Stem Cell Transplantation
JOURNAL OF CLINICAL IMMUNOLOGY,35(1):84-86 2015(Jan.)
Author:Shigemura, Tomonari; Nakazawa, Yozo; Hirabayashi, Koichi; Kobayashi, Norimoto; Sakashita, Kazuo; Agematsu, Kazunaga; Koike, Kenichi;


Evaluation of Mucorales DNA load in cerebrospinal fluid in a patient with possible cerebral mucormycosis treated with intravenous liposomal amphotericin B
INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES,29:200-202 2014(Dec.)
Author:Shigemura, Tomonari; Nakazawa, Yozo; Matsuda, Kazuyuki; Motobayashi, Mitsuo; Saito, Shoji; Koike, Kenichi;


Anti-leukemic potency of piggyBac-mediated CD 19-specific T cells against refractory Philadelphia chromosome-positive acute lymphoblastic leukemia
CYTOTHERAPY,16(9):1257-1269 2014(Sep.)
Author:Saito, Shoji; Nakazawa, Yozo; Sueki, Akane; Matsuda, Kazuyuki; Tanaka, Miyuki; Yanagisawa, Ryu; Maeda, Yasuhiro; Sato, Yuko; Okabe, Seiichi; Inukai, Takeshi; Sugita, Kanji; Wilson, Matthew H.; Rooney, Cliona M.; Koike, Kenichi;


Serial monitoring of Mucorales DNA load in serum samples of a patient with disseminated mucormycosis after allogeneic bone marrow transplantation
INTERNATIONAL JOURNAL OF HEMATOLOGY,100(2):206-209 2014(Aug.)
Author:Shigemura, Tomonari; Nakazawa, Yozo; Matsuda, Kazuyuki; Sano, Kenji; Yaguchi, Takashi; Motobayashi, Mitsuo; Saito, Shoji; Noda, Shunsuke; Kobayashi, Norimoto; Agematsu, Kazunaga; Honda, Takayuki; Koike, Kenichi;


Risk factors for diabetes mellitus and impaired glucose tolerance following allogeneic hematopoietic stem cell transplantation in pediatric patients with hematological malignancies
INTERNATIONAL JOURNAL OF HEMATOLOGY,99(4):477-486 2014(Apr.)
Author:Hirabayashi, Kanae; Nakazawa, Yozo; Matsuura, Hiroki; Hara, Yosuke; Kurata, Takashi; Hirabayashi, Koichi; Saito, Shoji; Yoshikawa, Kentaro; Tanaka, Miyuki; Yanagisawa, Ryu; Sakashita, Kazuo; Koike, Kenichi;


Successful cord blood transplantation after repeated transfusions of unmobilized neutrophils in addition to antifungal treatment in an infant with chronic granulomatous disease complicated by invasive pulmonary aspergillosis
TRANSFUSION,54(3):516-521 2014(Mar.)
Author:Shigemura, Tomonari; Nakazawa, Yozo; Yoshikawa, Kentaro; Hirabayashi, Koichi; Saito, Shoji; Kobayashi, Norimoto; Sakashita, Kazuo; Shiohara, Masaaki; Wada, Taizo; Shimodaira, Shigetaka; Agematsu, Kazunaga; Koike, Kenichi;


Sustained elevation of serum interleukin-18 and its association with hemophagocytic lymphohistiocytosis in XIAP deficiency
CYTOKINE,65(1):74-78 2014(Jan.)
Author:Wada, Taizo; Kanegane, Hirokazu; Ohta, Kazuhide; Katoh, Fumiyo; Imamura, Toshihiko; Nakazawa, Yozo; Miyashita, Ritsuko; Hara, Junichi; Hamamoto, Kazuko; Yang, Xi; Filipovich, Alexandra H.; Marsh, Rebecca A.; Yachie, Akihiro;


Cytokine production profiles in chronic relapsing-remitting experimental autoimmune encephalomyelitis: IFN-gamma and TNF-alpha are important participants in the first attack but not in the relapse
JOURNAL OF THE NEUROLOGICAL SCIENCES,340(1-2):117-122 2014
Author:Hidaka, Yoshihiko; Inaba, Yuji; Matsuda, Kazuyuki; Itoh, Makoto; Kaneyama, Tomoki; Nakazawa, Yozo; Koh, Chang-Sung; Ichikawa, Motoki;


Reduced-toxicity myeloablative conditioning consisting of 8-Gy total body irradiation, cyclophosphamide and fludarabine for pediatric hematological malignancies
SCIENTIFIC REPORTS,4 2014
Author:Hirabayashi, Koichi; Nakazawa, Yozo; Sakashita, Kazuo; Kurata, Takashi; Saito, Shoji; Yoshikawa, Kentaro; Tanaka, Miyuki; Yanagisawa, Ryu; Koike, Kenichi;


Identification of a novel HLA-A*24:02-restricted adenovirus serotype 11-specific CD8(+) T-cell epitope for adoptive immunotherapy
MOLECULAR IMMUNOLOGY,56(4):399-405 2013(Dec.)
Author:Imahashi, Nobuhiko; Nishida, Tetsuya; Ito, Yoshinori; Kawada, Jun-ichi; Nakazawa, Yozo; Toji, Shingo; Suzuki, Susumu; Terakura, Seitaro; Kato, Tomonori; Murata, Makoto; Naoe, Tomoki;


Usefulness of Allogeneic Hematopoietic Stem Cell Transplantation in First Complete Remission for Pediatric Blastic Plasmacytoid Dendritic Cell Neoplasm With Skin Involvement: A Case Report and Review of Literature
PEDIATRIC BLOOD & CANCER,60(11):E140-E142 2013(Nov.)
Author:Sakashita, Kazuo; Saito, Shoji; Yanagisawa, Ryu; Tanaka, Miyuki; Yoshikawa, Kentaro; Hirabayashi, Koichi; Tsukahara, Keiko; Motobayashi, Mitsuo; Nakazawa, Yozo; Koike, Kenichi;


Replaced platelet concentrates containing a new additive solution, M-sol: safety and efficacy for pediatric patients
TRANSFUSION,53(9):2053-2060 2013(Sep.)
Author:Yanagisawa, Ryu; Shimodaira, Shigetaka; Kojima, Shunsuke; Nakasone, Nobuhiko; Ishikawa, Shinsuke; Momose, Kayo; Honda, Takayuki; Yoshikawa, Kentaro; Saito, Shoji; Tanaka, Miyuki; Nakazawa, Yozo; Sakashita, Kazuo; Shiohara, Masaaki; Akino, Mitsuaki; Hirayama, Junichi; Azuma, Hiroshi; Koike, Kenichi;


Evaluation of Long-term Transgene Expression in piggyBac-Modified Human T Lymphocytes
JOURNAL OF IMMUNOTHERAPY,36(1):3-10 2013(Jan.)
Author:Nakazawa, Yozo; Saha, Sunandan; Galvan, Daniel L.; Huye, Leslie; Rollins, Lisa; Rooney, Cliona M.; Wilson, Matthew H.;


piggyBac Transposon System Modification of Primary Human T Cells
JOVE-JOURNAL OF VISUALIZED EXPERIMENTS,(69) 2012(Nov.)
Author:Saha, Sunandan; Nakazawa, Yozo; Huye, Leslie E.; Doherty, Joseph E.; Galvan, Daniel L.; Rooney, Cliona M.; Wilson, Matthew H.;


Food allergy after cord blood transplantation in children
BRITISH JOURNAL OF HAEMATOLOGY,158(5):672-676 2012(Sep.)
Author:Sakashita, Kazuo; Nakazawa, Yozo; Yanagisawa, Ryu; Tanaka, Miyuki; Saito, Shoji; Yoshikawa, Kentaro; Hirabayashi, Koichi; Kusakari, Mai; Kato, Sawako; Hidaka, Nao; Nakayama, Yoshiko; Shigemura, Tomonari; Kobayashi, Norimoto; Kobayashi, Mikiko; Shiohara, Masaaki; Koike, Kenichi;


Clinical features and outcome of X-linked lymphoproliferative syndrome type 1 (SAP deficiency) in Japan identified by the combination of flow cytometric assay and genetic analysis
PEDIATRIC ALLERGY AND IMMUNOLOGY,23(5):488-493 2012(Aug.)
Author:Kanegane, Hirokazu; Yang, Xi; Zhao, Meina; Yamato, Kazumi; Inoue, Masami; Hamamoto, Kazuko; Kobayashi, Chie; Hosono, Ako; Ito, Yoshikiyo; Nakazawa, Yozo; Terui, Kiminori; Kogawa, Kazuhiro; Ishii, Eiichi; Sumazaki, Ryo; Miyawaki, Toshio;


Long-term haematological improvement after non-intensive or no chemotherapy in juvenile myelomonocytic leukaemia and poor correlation with adult myelodysplasia spliceosome-related mutations
BRITISH JOURNAL OF HAEMATOLOGY,157(5):647-650 2012(Jun.)
Author:Matsuda, Kazuyuki; Yoshida, Nao; Miura, Shuhei; Nakazawa, Yozo; Sakashita, Kazuo; Hyakuna, Nobuyuki; Saito, Masahiro; Kato, Fumiyo; Ogawa, Atsushi; Watanabe, Akihiro; Sotomatsu, Manabu; Kobayashi, Chie; Ito, Toshiro; Ishida, Fumihiro; Manabe, Atsushi; Kojima, Seiji; Koike, Kenichi;


Critical Illness Polyneuropathy and Myopathy Caused by Bacillus Cereus Sepsis in Acute Lymphoblastic Leukemia
JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY,34(3):E110-E113 2012(Apr.)
Author:Hirabayashi, Koichi; Shiohara, Masaaki; Suzuki, Takefumi; Saito, Shoji; Tanaka, Miyuki; Yanagisawa, Ryu; Tsuruta, Goro; Fukuyama, Tetsuhiro; Hidaka, Yoshihiko; Nakazawa, Yozo; Shimizu, Takashi; Sakashita, Kazuo; Koike, Kenichi;


Combining mTor Inhibitors With Rapamycin-resistant T Cells: A Two-pronged Approach to Tumor Elimination
MOLECULAR THERAPY,19(12):2239-2248 2011(Dec.)
Author:Huye, Leslie E.; Nakazawa, Yozo; Patel, Mayuri P.; Yvon, Eric; Sun, Jiali; Savoldo, Barbara; Wilson, Matthew H.; Dotti, Gianpietro; Rooney, Cliona M.;


Prophylactic treatment for hypertension and seizure in a case of allogeneic hematopoietic stem cell transplantation after posterior reversible encephalopathy syndrome
PEDIATRIC TRANSPLANTATION,15(8):E169-E173 2011(Dec.)
Author:Fukuyama, Tetsuhiro; Tanaka, Miyuki; Nakazawa, Yozo; Motoki, Noriko; Inaba, Yuji; Higuchi, Tsukasa; Koike, Kenichi;


Genetic analysis of TP53 in childhood myelodysplastic syndrome and juvenile myelomonocytic leukemia
LEUKEMIA RESEARCH,35(12):1578-1584 2011(Dec.)
Author:Saito, Shoji; Matsuda, Kazuyuki; Taira, Chiaki; Sano, Kenji; Tanaka-Yanagisawa, Miyuki; Yanagisawa, Ryu; Nakazawa, Yozo; Sakashita, Kazuo; Shiohara, Masaaki; Koike, Kenichi;


Telecommunication system for children undergoing stem cell transplantation
PEDIATRICS INTERNATIONAL,53(6):1002-1009 2011(Dec.)
Author:Higuchi, Kazumi; Nakazawa, Yozo; Sakata, Nobuhiro; Takizawa, Masaomi; Ohso, Keiko; Tanaka, Miyuki; Yanagisawa, Ryu; Koike, Kenichi;


PiggyBac-mediated Cancer Immunotherapy Using EBV-specific Cytotoxic T-cells Expressing HER2-specific Chimeric Antigen Receptor
MOLECULAR THERAPY,19(12):2133-2143 2011(Dec.)
Author:Nakazawa, Yozo; Huye, Leslie E.; Salsman, Vita S.; Leen, Ann M.; Ahmed, Nabil; Rollins, Lisa; Dotti, Gianpietro; Gottschalk, Stephen M.; Wilson, Matthew H.; Rooney, Cliona M.;


Disappearance of Minimal Residual Disease After the Early Withdrawal of Immunosuppressants in a Patient With Juvenile Myelomonocytic Leukemia
PEDIATRIC BLOOD & CANCER,56(3):501-502 2011(Mar.)
Author:Yanagisawa, Ryu; Matsuda, Kazuyuki; Sakashita, Kazuo; Nakazawa, Yozo; Tanaka, Miyuki; Saito, Shoji; Yoshikawa, Kentaro; Kamijo, Takehiko; Shiohara, Masaaki; Koike, Kenichi;


Early and Rapid Detection of X-Linked Lymphoproliferative Syndrome with SH2D1A Mutations by Flow Cytometry
CYTOMETRY PART B-CLINICAL CYTOMETRY,80B(1):8-13 2011(Jan.)
Author:Zhao, Meina; Kanegane, Hirokazu; Kobayashi, Chie; Nakazawa, Yozo; Ishii, Eizaburo; Kasai, Mikio; Terui, Kiminori; Gocho, Yoshihiro; Imai, Kohsuke; kiyasu, Junichi; Nonoyama, Shigeaki; Miyawaki, Toshio;


Detection of T-cell receptor gene rearrangement in children with Epstein-Barr virus-associated hemophagocytic lymphohistiocytosis using the BIOMED-2 multiplex polymerase chain reaction combined with GeneScan analysis
CLINICA CHIMICA ACTA,412(17-18):1554-1558 2011
Author:Matsuda, Kazuyuki; Nakazawa, Yozo; Yanagisawa, Ryu; Honda, Takayuki; Ishii, Eiichi; Koike, Kenichi;


Increased pretransplant QT dispersion as a risk factor for the development of cardiac complications during and after preparative conditioning for pediatric allogeneic hematopoietic stem cell transplantation
PEDIATRIC TRANSPLANTATION,14(8):986-992 2010(Dec.)
Author:Motoki, Noriko; Shimizu, Takashi; Akazawa, Yohei; Saito, Shoji; Tanaka, Miyuki; Yanagisawa, Ryu; Motoki, Hirohiko; Nakazawa, Yozo; Sakashita, Kazuo; Iwasaki, Yasushi; Shiohara, Masaaki; Koike, Kenichi;


Purification, Biochemical Characterization, and Cloning of Phospholipase D from Streptomyces racemochromogenes Strain 10-3
PROTEIN JOURNAL,29(8):598-608 2010(Nov.)
Author:Nakazawa, Yozo; Sagane, Yoshimasa; Kikuchi, Teppei; Uchino, Masataka; Nagai, Takeshi; Sato, Hiroaki; Toeda, Kazuki; Takano, Katsumi;


piggyBac Transposon/Transposase System to Generate CD19-Specific T Cells for the Treatment of B-Lineage Malignancies
HUMAN GENE THERAPY,21(4):427-437 2010(Apr.)
Author:Manuri, Pallavi V. Raja; Wilson, Matthew H.; Maiti, Sourindra N.; Mi, Tiejuan; Singh, Harjeet; Olivares, Simon; Dawson, Margaret J.; Huls, Helen; Lee, Dean A.; Rao, Pulivarthi H.; Kaminski, Joseph M.; Nakazawa, Yozo; Gottschalk, Stephen; Kebriaei, Partow; Shpall, Elizabeth J.; Champlin, Richard E.; Cooper, Laurence J. N.;


Long-term survival after nonintensive chemotherapy in some juvenile myelomonocytic leukemia patients with CBL mutations, and the possible presence of healthy persons with the mutations
BLOOD,115(26):5429-5431 2010
Author:Matsuda, Kazuyuki; Taira, Chiaki; Sakashita, Kazuo; Saito, Shoji; Tanaka-Yanagisawa, Miyuki; Yanagisawa, Ryu; Nakazawa, Yozo; Shiohara, Masaaki; Fukushima, Keitaro; Oda, Megumi; Honda, Takayuki; Nakahata, Tatsutoshi; Koike, Kenichi;


Polymyxin-Direct Hemoperfusion for Sepsis-Induced Multiple Organ Failure
PEDIATRIC BLOOD & CANCER,55(1):202-205 2010
Author:Hirabayashi, Koichi; Shiohara, Masaaki; Saito, Shoji; Tanaka, Miyuki; Yanagisawa, Ryu; Tsuruta, Goro; Fukuyama, Tetsuhiro; Hidaka, Yoshihiko; Nakazawa, Yozo; Shimizu, Takashi; Sakashita, Kazuo; Koike, Kenichi;


Optimization of the PiggyBac Transposon System for the Sustained Genetic Modification of Human T Lymphocytes
JOURNAL OF IMMUNOTHERAPY,32(8):826-836 2009(Oct.)
Author:Nakazawa, Yozo; Huye, Leslie E.; Dotti, Gianpietro; Foster, Aaron E.; Vera, Juan F.; Manuri, Pallavi R.; June, Carl H.; Rooney, Cliona M.; Wilson, Matthew H.;


Genome-wide Mapping of PiggyBac Transposon Integrations in Primary Human T Cells
JOURNAL OF IMMUNOTHERAPY,32(8):837-844 2009(Oct.)
Author:Galvan, Daniel L.; Nakazawa, Yozo; Kaja, Aparna; Kettlun, Claudia; Cooper, Laurence J. N.; Rooney, Cliona M.; Wilson, Matthew H.;


Low toxicity of a conditioning with 8-Gy total body irradiation, fludarabine and cyclophosphamide as preparative regimen for allogeneic hematopoietic stem cell transplantation in pediatric hematological malignancies
PEDIATRIC TRANSPLANTATION,13(6):737-745 2009(Sep.)
Author:Yanagisawa, Ryu; Nakazawa, Yozo; Sakashita, Kazuo; Tanaka, Miyuki; Shikama, Naoto; Kamijo, Takehiko; Shiohara, Masaaki; Koike, Kenichi;


Urinary excretion of ganciclovir contributes to improvement of adenovirus-associated hemorrhagic cystitis after allogeneic bone marrow transplantation
PEDIATRIC TRANSPLANTATION,13(5):632-635 2009(Aug.)
Author:Nakazawa, Yozo; Suzuki, Takefumi; Fukuyama, Tetsuhiro; Katsuyama, Yoshihiko; Tanaka, Miyuki; Yanagisawa, Ryu; Sakashita, Kazuo; Shiohara, Masaaki; Koike, Kenichi;


High incidence of meropenem resistance among alpha-hemolytic streptococci in children with cancer
PEDIATRICS INTERNATIONAL,51(1):103-106 2009(Feb.)
Author:Abe, Masako; Kamijo, Takehiko; Matsuzawa, Shigeyuki; Miki, Jun; Nakazawa, Yozo; Sakashita, Kazuo; Okabe, Tadashi; Honda, Takayuki; Mitsuyama, Jun-ichi; Koike, Kenichi;


A conditioning regimen of busulfan, fludarabine, and melphalan for allogeneic stem cell transplantation in children with juvenile myelomonocytic leukemia
PEDIATRIC TRANSPLANTATION,12(8):862-867 2008(Dec.)
Author:Yabe, Miharu; Sako, Masahiro; Yabe, Hiromasa; Osugi, Yuko; Kurosawa, Hidemitsu; Nara, Taemi; Tokuyama, Mika; Adachi, Souichi; Kobayashi, Chie; Yanagimachi, Masakatsu; Ohtsuka, Yoshitoshi; Nakazawa, Yozo; Ogawa, Chitose; Manabe, Atsushi; Kojima, Seiji; Nakahata, Tatsutoshi; Japanese Childhood MDS Study Grp;


Exploiting cytokine secretion to rapidly produce multivirus-specific T cells for adoptive immunotherapy
JOURNAL OF IMMUNOTHERAPY,31(7):665-674 2008(Sep.)
Author:Fujita, Yuriko; Leen, Ann M.; Sun, Jiali; Nakazawa, Yozo; Yvon, Eric; Heslop, Helen E.; Brenner, Malcohn K.; Rooney, Cliona M.;


Promising approach for aggressive NK cell leukaemia with allogeneic haematopoietic cell transplantation
EUROPEAN JOURNAL OF HAEMATOLOGY,81(2):107-111 2008(Aug.)
Author:Ito, Toshiro; Makishima, Hideki; Nakazawa, Hideyuki; Kobayashi, Hikaru; Shimodaira, Shigetaka; Nakazawa, Yozo; Kitano, Kiyoshi; Matsuda, Kazuyuki; Hidaka, Eiko; Ishida, Fumihiro;


Long-term Follow-up of Plasma Cells in Bone Marrow and Serum Free Light Chains in Primary Systemic AL Amyloidosis
INTERNAL MEDICINE,47(20):1783-1790 2008
Author:Yoshida, Takuhiro; Matsuda, Masayuki; Katoh, Nagaaki; Tazawa, Ko-ichi; Shimojima, Yasuhiro; Gono, Takahisa; Ishii, Wataru; Nakazawa, Yozo; Sakashita, Kazuo; Koike, Kenichi; Yamada, Toshiyuki; Ikeda, Shu-ichi;


Acquisition of loss of the wild-type NRAS locus with aggressive disease progression in a patient with juvenile myelomonocytic leukemia and a heterozygous NRAS mutation
HAEMATOLOGICA-THE HEMATOLOGY JOURNAL,92(11):1576-1578 2007(Nov.)
Author:Matsuda, Kazuyuki; Nakazawa, Yozo; Sakashita, Kazuo; Shiohara, Masaaki; Yamauchi, Kazuyoshi; Koike, Kenichi;


Chemokine system and tissue infiltration in aggressive NK-cell leukemia
LEUKEMIA RESEARCH,31(9):1237-1245 2007(Sep.)
Author:Makishima, Hideki; Ito, Toshiro; Momose, Kayoko; Nakazawa, Hideyuki; Shimodaira, Shigetaka; Kamijo, Yuji; Nakazawa, Yozo; Ichikawa, Naoaki; Ueno, Mayumi; Kobayashi, Hikaru; Kitano, Kiyoshi; Saito, Hiroshi; Kiyosawa, Kendo; Ishida, Fumihiro;


Outcome of non-T-cell-depleted HLA-haploidentical hematopoietic stem cell transplantation from family donors in children and adolescents
INTERNATIONAL JOURNAL OF HEMATOLOGY,85(3):246-255 2007(Apr.)
Author:Yoshihara, Takao; Okada, Keiko; Kobayashi, Michihiro; Kikuta, Atsushi; Kato, Koji; Adachi, Naoto; Kikuchi, Akira; Ishida, Hiroyuki; Hirota, Yasuzou; Kuroda, Hiroshi; Nagatoshi, Yoshihisa; Inukai, Takeshi; Koike, Kazutoshi; Kigasawa, Hisato; Yagasaki, Hiroshi; Tokuda, Kiriko; Kishimoto, Tomoko; Nakano, Takahide; FJjita, Naoto; Goto, Hiroaki; Nakazawa, Yozo; Kanegane, Hirokazu; Matsuzaki, Akinobu; Osugi, Yuko; Hasegawa, Daiichiro; Uoshima, Nobuhiko; Nakamura, Kazuhiro; Tsuchida, Masahiro; Tanaka, Ryuhei; Watanabe, Arata; Yabe, Hiromasa;


A possible role for the production of multiple HLA antibodies in fatal platelet transfusion refractoriness after peripheral blood progenitor cell transplantation from the mother in a patient with relapsed leukemia
TRANSFUSION,47(2):326-334 2007(Feb.)
Author:Nakazawa, Yozo; Saito, Satoshi; Hasegawa, Yasuhisa; Yanagisawa, Ryu; Sakashita, Kazuo; Kamijo, Takehiko; Miyazaki, Toru; Sato, Shinichiro; Ikeda, Hisami; Ikebuchi, Kenji; Koike, Kenichi;


Spontaneous improvement of hematologic abnormalities in patients having juvenile myelomonocytic leukemia with specific RAS mutations
BLOOD,109(12):5477-5480 2007
Author:Matsuda, Kazuyuki; Shimada, Akira; Yoshida, Nao; Ogawa, Atsushi; Watanabe, Akihiro; Yajima, Shuhei; Iizuka, Susumu; Koike, Kazutoshi; Yanai, Fumio; Kawasaki, Keiichiro; Yanagimachi, Masakatsu; Kikuchi, Akira; Ohtsuka, Yoshitoshi; Hidaka, Eiko; Yamauchi, Kazuyoshi; Tanaka, Miyuki; Yanagisawa, Ryu; Nakazawa, Yozo; Shiohara, Masaaki; Manabe, Atsushi; Kojima, Seiji; Koike, Kenichi;


A complex karyotype, including a three-way translocation generating a NUP98-HOXD13 transcript, in an infant with acute myeloid leukemia
CANCER GENETICS AND CYTOGENETICS,176(2):137-143 2007
Author:Hidaka, Eiko; Tanaka, Miyuki; Matsuda, Kazuyuki; Ishikawa-Matsumura, Masayo; Yamauchi, Kazuyoshi; Sano, Kenji; Honda, Takayuki; Wakui, Keiko; Yanagisawa, Ryu; Nakazawa, Yozo; Sakashita, Kazuo; Shiohara, Masaaki; Ishii, Eizaburo; Koike, Kenichi;

研究費
受託研究
2018 - 2023 , 日本発の遺伝子改変T細胞の実用化を促進するための、霊長類モデルを用いた安全性評価系の基盤整備
2017 - 2019 , CD116陽性骨髄系腫瘍を標的とした非ウイルス遺伝子改変キメラ抗原受容体T細胞の非臨床試験

科学研究費補助金(研究代表者)
2017 - 2019 , 再発・治療不応性T細胞性白血病に対するキメラ抗原受容体T細胞療法の開発 , 基盤研究(C)
2014 - 2016 , 難治性急性骨髄性白血病に対するFLT3を標的とした遺伝子改変T細胞療法の開発 , 基盤研究(C)
2011 - 2013 , 進行性神経芽腫に対するGD2特異的キメラ抗原受容体を用いた遺伝子改変T細胞療法 , 基盤研究(C)
2005 - 2006 , 若年性骨髄単球性白血病におけるポリコーム遺伝子による癌抑制経路不活化機構の解析 , 若手研究(B)