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中沢 洋三  ナカザワ ヨウゾウ

教員組織学術研究院(医学系)電話番号
教育組織医学部 医学科 小児医学FAX番号
職名教授メールアドレスyxnakaza@shinshu-u.ac.jp
住所ホームページURL

更新日:2021/07/19

プロフィール

研究分野
小児科学
学歴
出身大学院
2015 , 信州大学大学院医学系研究科

取得学位
医学博士 , 信州大学大学院医学系研究科

研究活動業績

研究業績(著書・
発表論文等)
論文
Hematopoietic stem cell transplantation for pediatric acute promyelocytic leukemia in Japan
Pediatr Blood Cancer,67(5):e28181 2020(May)
Author:Yamamoto S, Tomizawa D, Kudo K, Hasegawa D, Taga T, Yanada M, Kondo T, Nakazawa Y, Eto T, Inoue M, Kato K, Atsuta Y, Ishida H.


Comparative analysis of graft-versus-host disease prophylaxis with tacrolimus in combination with methylprednisolone or methotrexate after umbilical cord blood transplantation
Int J Hematol,111(5):702-710 2020(May)
Author:Shigemura T, Sakashita K, Okura E, Morita D, Komori K, Kurata T, Hirabayashi K, Saito S, Tanaka M, Yanagisawa R, Nakazawa Y.


Usefulness of Continuous Glucose Monitoring for Prevention and Early Detection of Hypoglycemia Caused by a Ketogenic Diet and Late Dumping Syndrome
Pediatr Neurol,105:65-66 2020(Apr.)
Author:Morikawa M, Hara Y, Nakazawa Y, Inaba Y, Motobayashi M.


Delayed methotrexate clearance and acute kidney injury after high-dose methotrexate chemotherapy concurrent with dasatinib in a patient with relapsed Philadelphia chromosome-positive acute lymphoblastic leukemia: A case report
Pediatr Blood Cancer,67(4):e28173 2020(Apr.)
Author:Morota H, Saito S, Uchida E, Okura E, Matsuoka D, Hidaka Y, Natsume T, Watanabe T, Shigemura T, Morita D, Tanaka M, Kurata T, Sakashita K, Nakazawa Y.


Complete measurable residual disease response after combination chemotherapy with AML-type and ALL-type regimens in pediatric B/myeloid acute bilineal leukemia
Leuk Lymphoma,61(4):967-970 2020(Apr.)
Author:Saito S, Taira C, Matsuda K, Yanagisawa R, Morita D, Shigemura T, Yoshikawa K, Tanaka M, Sakashita K, Mukai S, Shimodaira S, Koike K, Nakazawa Y.


PCDH17 functions as a common tumor suppressor gene in acute leukemia and its transcriptional downregulation is mediated primarily by aberrant histone acetylation, not DNA methylation
Int J Hematol,111(3):451-462 2020(Mar.)
Author:Thanh Nha Uyen L, Amano Y, Al-Kzayer LFY, Kubota N, Kobayashi J, Nakazawa Y, Koike K, Sakashita K.


Impact of infliximab administration before plasma exchange therapy on patients with Kawasaki disease
Ther Apher Dial 2020(Feb. 19)
Author:Shimada S, Matsuoka D, Murase T, Hachiya A, Motoki N, Nakazawa Y.


Dexamethasone palmitate is a feasible option for the treatment of chronic graft-vs-host disease, particularly with macrophage hyperactivation
Pediatr Transplant,24(1):e13627 2020(Feb.)
Author:Kurosawa Y, Morita D, Shibazaki T, Komori K, Motobayashi M, Shigemura T, Tanaka M, Nakazawa Y.


Multiple heterogeneous bone invasions of B lymphoblastic lymphoma with the TCF3/PBX1 fusion gene: a case report
Int J Hematol,111(2):163-165 2020(Feb.)
Author:Okura E, Saito S, Natsume T, Morita D, Tanaka M, Kiyokawa N, Nakazawa Y.


A Rapid Cytologic Double Staining of Epstein-Barr Virus-encoded Small RNA and Cell Surface Markers for Diagnosis of Epstein-Barr Virus-associated Hemophagocytic Lymphohistiocytosis
J Pediatr Hematol Oncol 2019(Nov. 14)
Author:Takahashi N, Kudo K, Tanaka M, Kumagai N, Sato T, Kamio T, Sasaki S, Terui K, Kurose A, Yanagisawa R, Nakazawa Y, Ito E.


Prevention of transfusion-transmitted cytomegalovirus infection using leukoreduced blood components in patients receiving seronegative umbilical cord blood transplantation
Transfusion,59(10):3065-3070 2019(Oct.)
Author:Shigemura T, Yanagisawa R, Komori K, Morita D, Kurata T, Tanaka M, Sakashita K, Nakazawa Y.


Retrospective analysis of children with high-risk acute myeloid leukemia who underwent allogeneic hematopoietic stem cell transplantation following complete remission with initial induction chemotherapy in the AML-05 clinical trial
Pediatr Blood Cancer,66(10):e27875 2019(Oct.)
Author:Hyakuna N, Hashii Y, Ishida H, Umeda K, Takahashi Y, Nagasawa M, Yabe H, Nakazawa Y, Koh K, Goto H, Fujisaki H, Matsumoto K, Kakuda H, Yano M, Tawa A, Tomizawa D, Taga T, Adachi S, Kato K.


Essential role of PTPN11 mutation in enhanced haematopoietic differentiation potential of induced pluripotent stem cells of juvenile myelomonocytic leukaemia
Br J Haematol,187(2):163-173 2019(Oct.)
Author:Shigemura T, Matsuda K, Kurata T, Sakashita K, Okuno Y, Muramatsu H, Yue F, Ebihara Y, Tsuji K, Sasaki K, Nakahata T, Nakazawa Y, Koike K.


Proton Beam Therapy for Adolescent Primary Central Nervous System Lymphoma With Residual Tumor After Intensive Chemotherapy: A Case Report
Pract Radiat Oncol,9(5):333-337 2019(Sep.)
Author:Komori K, Saito S, Araya M, Morita D, Kurata T, Hirabayashi K, Tanaka M, Koiwai K, Tauchi K, Masaki H, Nakazawa Y.


Hematopoietic stem-cell transplantation in children with refractory acute myeloid leukemia
Bone Marrow Transplant,54(9):1489-1498 2019(Sep.)
Author:Okamoto Y, Kudo K, Tabuchi K, Tomizawa D, Taga T, Goto H, Yabe H, Nakazawa Y, Koh K, Ikegame K, Yoshida N, Uchida N, Watanabe K, Koga Y, Inoue M, Kato K, Atsuta Y, Ishida H.


Maternal Exposure to Housing Renovation During Pregnancy and Risk of Offspring with Congenital Malformation: The Japan Environment and Children's Study
Sci Rep,9(1):11564 2019(Aug. 09)
Author:Motoki N, Inaba Y, Shibazaki T, Misawa Y, Ohira S, Kanai M, Kurita H, Nakazawa Y, Tsukahara T, Nomiyama T; Japan Environment & Children’s Study (JECS) Group.


Alcohol Consumption During Pregnancy and Risk of Placental Abnormality: The Japan Environment and Children's Study
Sci Rep,9(1):10259 2019(Jul. 16)
Author:Ohira S, Motoki N, Shibazaki T, Misawa Y, Inaba Y, Kanai M, Kurita H, Shiozawa T, Nakazawa Y, Tsukahara T, Nomiyama T; Japan Environment & Children’s Study (JECS) Group.


A low-frequency IL4R locus variant in Japanese patients with intravenous immunoglobulin therapy-unresponsive Kawasaki disease
Pediatr Rheumatol Online J,17(1):34 2019(Jul. 03)
Author:Amano Y, Akazawa Y, Yasuda J, Yoshino K, Kojima K, Kobayashi N, Matsuzaki S, Nagasaki M, Kawai Y, Minegishi N, Ishida N, Motoki N, Hachiya A, Nakazawa Y, Yamamoto M, Koike K, Takeshita T.


Significance of Molecular Monitoring of T Cells for the Decision of Treatment Strategy for Epstein-Barr Virus-associated Hemophagocytic Lymphohistiocytosis
J Pediatr Hematol Oncol,41(5):407-409 2019(Jul.)
Author:Saito T, Tanaka M, Matsuda K, Honma H, Komori K, Morita D, Nakazawa H, Yanagisawa R, Nakazawa Y.


DOCK8 mutation diagnosed using whole-exome sequencing of the dried blood spot-derived DNA: a case report of an Iraqi girl diagnosed in Japan
BMC Med Genet,20(1):114 2019(Jun. 26)
Author:Al-Kzayer LFY, Al-Aradi HMH, Shigemura T, Sano K, Tanaka M, Hamada M, Ali KH, Aldaghir OM, Nakazawa Y, Okuno Y.


Correction to: Factors predicting the recurrence of Epstein-Barr virus-associated hemophagocytic lymphohistiocytosis in children after treatment using the HLH-2004 protocol
Int J Hematol,109(5):629 2019(May)
Author:Yanagisawa R, Matsuda K, Ohga S, Kanegane H, Morimoto A, Okamoto Y, Ohara A, Fukushima K, Sotomatsu M, Nomura K, Saito AM, Horibe K, Ishii E, Nakazawa Y.


Factors predicting the recurrence of Epstein-Barr virus-associated hemophagocytic lymphohistiocytosis in children after treatment using the HLH-2004 protocol
Int J Hematol,109(5):612-617 2019(May)
Author:Yanagaisawa R, Matsuda K, Ohga S, Kanegane H, Morimoto A, Okamoto Y, Ohara A, Fukushima K, Sotomatsu M, Nomura K, Saito AM, Horibe K, Ishii E, Nakazawa Y.


Ovarian function after allogeneic hematopoietic stem cell transplantation in children and young adults given 8-Gy total body irradiation-based reduced-toxicity myeloablative conditioning
Pediatr Transplant,23(3):e13372 2019(May)
Author:Komori K, Hirabayashi K, Morita D, Hara Y, Kurata T, Saito S, Tanaka M, Yanagisawa R, Sakashita K, Koike K, Nakazawa Y.


Neurocutaneous Melanosis in Association With Large Congenital Melanocytic Nevi in Children: A Report of 2 Cases With Clinical, Radiological, and Pathogenetic Evaluation
Front Neurol,10:79 2019(Feb. 07)
Author:Chen L, Zhai L, Al-Kzayer LFY, Sarsam SN, Liu T, Alzakar RH, Nakazawa Y.


Outcomes in children with hemophagocytic lymphohistiocytosis treated using HLH-2004 protocol in Japan
Int J Hematol,109(2):206-213 2019(Feb.)
Author:Yanagisawa R, Nakazawa Y, Matsuda K, Yasumi T, Kanegane H, Ohga S, Morimoto A, Hashii Y, Imaizumi M, Okamoto Y, Saito AM, Horibe K, Ishii E; HLH/LCH committee members of the Japan Children’s Cancer Group.


A Syrian Refugee in Iraq Diagnosed as a Case of IL12RB1 Deficiency in Japan Using Dried Blood Spots
Front Immunol,10:58 2019(Jan. 25)
Author:Al-Kzayer LFY, Yassin AK, Salih KH, Shigemura T, Sano K, Al-Simaani RBY, Tanaka M, Nakazawa Y, Okuno Y.


Mosaicism of an ELANE Mutation in an Asymptomatic Mother
J Clin Immunol,39(1):106-111 2019(Jan.)
Author:Shigemura T, Kobayashi N, Agematsu K, Ohara O, Nakazawa Y.


Comparison of conditioning regimens for autologous stem cell transplantation in children with acute myeloid leukemia: A nationwide retrospective study in Japan
Pediatr Blood Cancer,66(1):e27459 2019(Jan.)
Author:Sakaguchi H, Muramatsu H, Hasegawa D, Kudo K, Ishida H, Yoshida N, Koh K, Noguchi M, Shiba N, Tokimasa S, Fukuda T, Goto H, Miyamura T, Nakazawa Y, Hashii Y, Inoue M, Atsuta Y; Pediatric AML Working Group of the Japan Society for Hematopoietic Cell Transplantation.


Epstein-Barr Virus (EBV)-induced B-cell Lymphoproliferative Disorder Mimicking the Recurrence of EBV-associated Hemophagocytic Lymphohistiocytosis
J Pediatr Hematol Oncol,41(1):e44-e46 2019(Jan.)
Author:Yatsushiro Y, Nishikawa T, Saito A, Nakazawa Y, Imadome KI, Nakagawa S, Kodama Y, Okamoto Y, Kanegane H, Kawano Y.


Cisplatin-induced nephrotoxicity in patients with advanced neuroblastoma.
Pediatr Blood Cancer,65(9):e27253 2018(Sep.)
Author:Yanagisawa R, Kubota N, Hidaka E, Sakashita K, Tanaka M, Nakazawa Y, Nakamura T.


Postencephalitic epilepsy secondary to cytomegalovirus encephalitis.
Pediatr Int,60(8):758-760 2018(Aug.)
Author:Nasuno M, Shigemura T, Nakazawa Y, Inaba Y, Motobayashi M.


Integration Mapping of piggyBac-Mediated CD19 Chimeric Antigen Receptor T Cells Analyzed by Novel Tagmentation-Assisted PCR.
EBioMedicine,34:18-26 2018(Aug.)
Author:Hamada M, Nishio N, Okuno Y, Suzuki S, Kawashima N, Muramatsu H, Tsubota S, Wilson MH, Morita D, Kataoka S, Ichikawa D, Murakami N, Taniguchi R, Suzuki K, Kojima D, Sekiya Y, Nishikawa E, Narita A, Hama A, Kojima S, Nakazawa Y, Takahashi Y.


Childhood asymptomatic renal arteriovenous fistula 5 years after renal biopsy.
Pediatr Int,60(6):601-602 2018(Jun.)
Author:Matsuoka D, Hidaka Y, Kurozumi M, Tsukahara Y, Nakazawa Y.


An infant case of diffuse cerebrospinal lesions and cardiomyopathy caused by a BOLA3 mutation.
Brain Dev,40(6):484-488 2018(Jun.)
Author:Nishioka M, Inaba Y, Motobayashi M, Hara Y, Numata R, Amano Y, Shingu K, Yamamoto Y, Murayama K, Ohtake A, Nakazawa Y.


Co-occurrence of hypertrophic cardiomyopathy and juvenile myelomonocytic leukemia in a neonate with Noonan syndrome, leading to premature death.
Clin Case Rep,6(7):1202-1207 2018(May)
Author:Tamura A, Uemura S, Matsubara K, Kozuki E, Tanaka T, Nino N, Yokoi T, Saito A, Ishida T, Hasegawa D, Umeki I, Niihori T, Nakazawa Y, Koike K, Aoki Y, Kosaka Y.


Myelodysplastic syndrome in an infant with constitutional pure duplication 1q41-qter.
Hum Genome Var,5:6 2018(May)
Author:Morokawa H, Kamiya M, Wakui K, Kobayashi M, Kurata T, Matsuda K, Kawamura R, Kanno H, Fukushima Y, Nakazawa Y, Kosho T.


A Pediatric Case of Relapsing-Remitting Multiple Sclerosis Onset following Varicella Zoster Ophthalmicus with Optic Neuritis.
Case Rep Pediatr,2018:6931206 2018(Mar.)
Author:Shiba N, Inaba Y, Motobayashi M, Nishioka M, Kawasaki Y, Noda S, Matsuura H, Kobayashi N, Matsuoka T, Nakamura A, Nakazawa Y.


A pediatric case with peripheral facial nerve palsy caused by a granulomatous lesion associated with cat scratch disease.
Brain Dev,40(2):159-162 2018(Feb.)
Author:Nakamura C, Inaba Y, Tsukahara K, Mochizuki M, Sawanobori E, Nakazawa Y, Aoyama K.


Bacteremia due to Moraxella osloensis: a case report and literature review.
Braz J Infect Dis,22(1):60-62 2018(Jan.)
Author:Maruyama Y, Shigemura T, Aoyama K, Nagano N, Nakazawa Y.


Regional evaluation of childhood acute lymphoblastic leukemia genetic susceptibility loci among Japanese.
Sci Rep,8(1):789 2018(Jan.)
Author:Urayama KY, Takagi M, Kawaguchi T, Matsuo K, Tanaka Y, Ayukawa Y, Arakawa Y, Hasegawa D, Yuza Y, Kaneko T, Noguchi Y, Taneyama Y, Ota S, Inukai T, Yanagimachi M, Keino D, Koike K, Toyama D, Nakazawa Y, Kurosawa H, Nakamura K, Moriwaki K, et al.


Successful induction of therapeutic urinary concentration by intravenous ganciclovir and oral valganciclovir with remission of adenoviral hemorrhagic cystitis after cord blood transplantation.
Pediatr Transplant,:e13241 2018
Author:Yanagisawa T, Saito S, Katsuyama Y, Hirabayashi K, Shigemura T, Tanaka M, Sakashita K, Nakazawa Y.


Severe acyclovir-resistant herpes simplex virus 1 infection following cord blood transplantation.
Int J Hematol,:in press 2018
Author:Shigemura T, Nakazawa Y, Yoshikawa T, Fujii H, Yamada S, Saijo M, Okuyama R.


Asymmetrically enlarged parietal foramina in a rare case of Goldenhar syndrome with a possible etiopathogenesis.
Oncotarget,9(2):2962-2968 2017(Dec.)
Author:Al-Kzayer LFY, Sarsam SN, Alhur NY, Liu T, Nakazawa Y.


Enhanced Expression of Anti-CD19 Chimeric Antigen Receptor in piggyBac Transposon-Engineered T Cells.
Mol Ther Methods Clin Dev,8:131-140 2017(Dec.)
Author:Morita D, Nishio N, Saito S, Tanaka M, Kawashima N, Okuno Y, Suzuki S, Matsuda K, Maeda Y, Wilson MH, Dotti G, Rooney CM, Takahashi Y, Nakazawa Y.


Acute Myeloid Leukemia in a Patient With X-linked Severe Combined Immunodeficiency.
J Pediatr Hematol Oncol,39(8):e470-e472 2017(Nov.)
Author:Shigemura T, Motobayashi M, Matsuda K, Shimodaira T, Kurata T, Kobayashi N, Agematsu K, Nakazawa Y.


Clinical features of a female with WDR45 mutation complicated by infantile spasms: a case report and literature review.
Brain Dev,39(9):804-807 2017(Oct.)
Author:Morikawa M, Takano K, Motobayashi M, Shiba N, Kosho T, Nakazawa Y, Inaba Y.


Subclinical Neuroaxonal Damage in Patients With Clinically Mild Encephalitis/Encephalopathy With a Reversible Splenial Lesion.
Pediatr Neurol,74:e3-e4 2017(Sep.)
Author:Motobayashi M, Fukuyama T, Okuno-Yuguchi J, Tsukahara K, Nagaharu S, Hagimoto R, Kinoshita T, Nakazawa Y, Inaba Y.


Efficacy and safety of anagrelide in childhood essential thrombocythemia.
Pediatr Int,59(9):1017-1018 2017(Sep.)
Author:Kanai A, Morokawa H, Matsuda K, Shimazaki E, Nakazawa Y.


A case of GATA2-related myelodysplastic syndrome with unbalanced translocation der(1;7)(q10;p10).
Pediatr Blood Cancer,64(8) 2017(Aug.)
Author:Kurata T, Shigemura T, Muramatsu H, Okuno Y, Nakazawa Y.


Recurrent MYB rearrangement in blastic plasmacytoid dendritic cell neoplasm.
Leukemia,31(7):1629-1633 2017(Jul.)
Author:Suzuki K, Suzuki Y, Hama A, Muramatsu H, Nakatochi M, Gunji M, Ichikawa D, Hamada M, Taniguchi R, Kataoka S, Murakami N, Kojima D, Sekiya Y, Nishikawa E, Kawashima N, Narita A, Nishio N, Nakazawa Y, Iwafuchi H, Watanabe KI, Takahashi Y, Ito M, et al.


Abnormal hematopoiesis and autoimmunity in human subjects with germline IKZF1 mutations.
J Allergy Clin Immunol,140(1):223-231 2017(Jul.)
Author:Hoshino A, Okada S, Yoshida K, Nishida N, Okuno Y, Ueno H, Yamashita M, Okano T, Tsumura M, Nishimura S, Sakata S, Kobayashi M, Nakamura H, Kamizono J, Mitsui-Sekinaka K, Ichimura T, Ohga S, Nakazawa Y, Takagi M, Imai K, Shiraishi Y, Chiba K, et al.


Analysis of Serum Cytokine Profiles in Childhood-Onset Ocular Myasthenia Gravis.
Pediatr Neurol,69:e3-e4 2017(Apr.)
Author:Motobayashi M, Nishimura T, Nakazawa Y, Inaba Y.


Increasing Risk of Disturbed Root Development in Permanent Teeth in Childhood Cancer Survivors Undergoing Cancer Treatment at Older Age.
J Pediatr Hematol Oncol,39(3):e150-e154 2017(Apr.)
Author:Tanaka M, Kamata T, Yanagisawa R, Morita D, Saito S, Sakashita K, Shiohara M, Kurita H, Koike K, Nakazawa Y.


Mediastinal lesions across the age spectrum: a clinicopathological comparison between pediatric and adult patients.
Oncotarget,8(35):59845-59853 2017(Apr.)
Author:Liu T, Al-Kzayer LFY, Xie X, Fan H, Sarsam SN, Nakazawa Y, Chen L.


Dramatic Reduction in Tumor Size During 5 Months of Pazopanib Therapy in Combination With Ifosfamide, Carboplatin, and Etoposide in an Early Infant With Progressive Soft Tissue Sarcoma.
J Pediatr Hematol Oncol,39(2):154-156 2017(Mar.)
Author:Watanabe T, Kurata T, Sano K, Suzuki S, Kaneko T, Motobayashi M, Shigemura T, Sumi T, Koike K, Nakazawa Y.


Pediatric intestinal Behçet disease complicated by myeloid malignancies.
Int J Hematol,105(3):377-382 2017(Mar.)
Author:Kanamitsu K, Shimada A, Nishiuchi R, Shigemura T, Nakazawa Y, Koike K, Kodama Y, Shinkoda Y, Kawano Y, Yasui K, Sasaki K, Kajiwara R, Tsukahara H, Manabe A.


Aberrant methylation of protocadherin 17 and its prognostic value in pediatric acute lymphoblastic leukemia
Pediatr Blood Cancer,64(3):e26259 2017(Mar.)
Author:Uyen TN, Sakashita K, Al-Kzayer LF, et al.


Nonocclusive Mesenteric Ischemia after Chemotherapy in an Adolescent Patient with a History of Three Allogeneic Hematopoietic Stem Cell Transplantations for Acute Lymphoblastic Leukemia.
Pediatr Neonatol,58(1):81-84 2017(Feb.)
Author:Hirabayashi K, Takatsuki M, Motobayashi M, Kurata T, Saito S, Shigemura T, Nakazawa Y, Sakashita K, Ishizone S, Ota H, Koike K.


IFR4/MUM1-positive lymphoma in Waldeyer ring with co-expression of CD5 and CD10.
Pediatr Blood Cancer,64(2):311-314 2017(Feb.)
Author:Chen L, Al-Kzayer LF, Liu T, Kobayashi N, Nakazawa Y, Koike K.


Hematopoietic Stem Cell Transplantation for XIAP Deficiency in Japan.
J Clin Immunol,37(1):85-91 2017(Jan.)
Author:Ono S, Okano T, Hoshino A, Yanagimachi M, Hamamoto K, Nakazawa Y, Imamura T, Onuma M, Niizuma H, Sasahara Y, Tsujimoto H, Wada T, Kunisaki R, Takagi M, Imai K, Morio T, Kanegane H.


Aberrant methylation of protocadherin 17 and its prognostic value in pediatric acute lymphoblastic leukemia.
Pediatr Blood Cancer,64(3) 2017
Author:Uyen TN, Sakashita K, Al-Kzayer LF, Nakazawa Y, Kurata T, Koike K.


Early-onset colorectal cancer in young adult survivors of childhood cancer
PEDIATRICS INTERNATIONAL,58(7):637-639 2016(Jul.)
Author:Morita, Daisuke; Nakazawa, Yozo; Tanaka, Miyuki; Nakayama, Yoshiko; Koizumi, Tomonobu; Koike, Kenichi;


Enhancement of CAR Expression of piggyBac Transposon-Engineered T Cells by Stimulation with Viral Antigens
MOLECULAR THERAPY,24:S278-S279 2016(May)
Author:Morita, Daisuke; Tanaka, Miyuki; Nishio, Nobuhiro; Kawashima, Nozomu; Okuno, Yusuke; Wilson, Matthew H.; Rooney, Cliona M.; Takahashi, Yoshiyuki; Nakazawa, Yozo;


Clinical and Laboratory Outcomes After Umbilical Cord Blood Transplantation in a Patient with Mucolipidosis II Alpha/Beta
AMERICAN JOURNAL OF MEDICAL GENETICS PART A,170(5):1278-1282 2016(May)
Author:Shibazaki, Takumi; Hirabayashi, Koichi; Saito, Shoji; Shigemura, Tomonari; Nakazawa, Yozo; Sakashita, Kazuo; Takagi, Mineo; Shiohara, Masaaki; Adachi, Kaori; Nanba, Eiji; Sakai, Norio; Koike, Kenichi;


Immune Complex-Mediated Glomerulonephritis in a Patient with Wiskott-Aldrich Syndrome
JOURNAL OF CLINICAL IMMUNOLOGY,36(4):357-359 2016(May)
Author:Shigemura, Tomonari; Nakazawa, Yozo; Shimojo, Hisashi; Kobayashi, Norimoto; Agematsu, Kazunaga;


Loss of Mismatched HLA on the Leukemic Blasts of Patients With Relapsed Lymphoid Malignancies Following Bone Marrow Transplantation From Related Donors With HLA Class II Mismatches in the Graft Versus Host Direction
PEDIATRIC BLOOD & CANCER,63(4):709-711 2016(Apr.)
Author:Hirabayashi, Koichi; Kurata, Takashi; Horiuchi, Kazuki; Saito, Shoji; Shigemura, Tomonari; Tanaka, Miyuki; Yanagisawa, Ryu; Matsuda, Kazuyuki; Sakashita, Kazuo; Koike, Kenichi; Nakazawa, Yozo;


Anaplastic Large-Cell Lymphoma of the Left Ventricle Presenting With Arrhythmia and Cerebral Infarction due to Cardiogenic Embolism
PEDIATRIC BLOOD & CANCER,63(4):755-756 2016(Apr.)
Author:Hirabayashi, Koichi; Yamauchi, Shoko; Matsuzaki, Satoshi; Komatsu, Kazunori; Sano, Kenji; Koike, Kenichi; Nakazawa, Yozo;


Early detection of Rhizopus DNA in the serum of a patient with rhino-orbital-cerebral mucormycosis following allogeneic hematopoietic stem cell transplantation
INTERNATIONAL JOURNAL OF HEMATOLOGY,103(3):354-355 2016(Mar.)
Author:Shigemura, Tomonari; Nishina, Sayaka; Nakazawa, Hideyuki; Matsuda, Kazuyuki; Yaguchi, Takashi; Nakazawa, Yozo;


Intrathecal donor lymphocyte infusion for isolated leukemia relapse in the central nervous system following allogeneic stem cell transplantation: a case report and literature review
INTERNATIONAL JOURNAL OF HEMATOLOGY,103(1):107-111 2016(Jan.)
Author:Yanagisawa, Ryu; Nakazawa, Yozo; Sakashita, Kazuo; Saito, Shoji; Tanaka, Miyuki; Shiohara, Masaaki; Shimodaira, Shigetaka; Koike, Kenichi;


Anti-proliferative effects of T cells expressing a ligand-based chimeric antigen receptor against CD116 on CD34(+) cells of juvenile myelomonocytic leukemia
JOURNAL OF HEMATOLOGY & ONCOLOGY,9 2016
Author:Nakazawa, Yozo; Matsuda, Kazuyuki; Kurata, Takashi; Sueki, Akane; Tanaka, Miyuki; Sakashita, Kazuo; Imai, Chihaya; Wilson, Matthew H.; Koike, Kenichi;


Cytomegalovirus Encephalitis in a Patient with Severe Combined Immunodeficiency
JOURNAL OF CLINICAL IMMUNOLOGY,35(8):689-691 2015(Nov.)
Author:Motobayashi, Mitsuo; Shigemura, Tomonari; Tanaka, Miyuki; Kurata, Takashi; Kobayashi, Norimoto; Agematsu, Kazunaga; Amano, Yoshiro; Inaba, Yuji; Koike, Kenichi; Nakazawa, Yozo;


GATA2 and secondary mutations in familial myelodysplastic syndromes and pediatric myeloid malignancies
HAEMATOLOGICA,100(10):E398-E401 2015(Oct.)
Author:Wang, Xinan; Muramatsu, Hideki; Okuno, Yusuke; Sakaguchi, Hirotoshi; Yoshida, Kenichi; Kawashima, Nozomu; Xu, Yinyan; Shiraishi, Yuichi; Chiba, Kenichi; Tanaka, Hiroko; Saito, Shoji; Nakazawa, Yozo; Masunari, Taro; Hirose, Tadashi; Elmahdi, Shaimaa; Narita, Atsushi; Doisaki, Sayoko; Ismael, Olfat; Makishima, Hideki; Hama, Asahito; Miyano, Satoru; Takahashi, Yoshiyuki; Ogawa, Seishi; Kojima, Seiji;


Reduction in peripheral regulatory T cell population in childhood ocular type myasthenia gravis
BRAIN & DEVELOPMENT,37(8):808-816 2015(Sep.)
Author:Nishimura, Takafumi; Inaba, Yuji; Nakazawa, Yozo; Omata, Taku; Akasaka, Manami; Shirai, Ikuko; Ichikawa, Motoki;


SIGNIFICANCE OF MOLECULAR MONITORING IN CHILDREN WITH EPSTEIN-BARR VIRUS-ASSOCIATED HEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS
PEDIATRIC BLOOD & CANCER,62:S17-S17 2015(May)
Author:Yanagisawa, Ryu; Nakazawa, Yozo; Matsuda, Kazuyuki; Morimoto, Akira; Ishii, Eiichi; Japan Pediat Leukemia Lymphoma;


An Increase in Circulating B Cell-Activating Factor in Childhood-Onset Ocular Myasthenia Gravis
PEDIATRIC NEUROLOGY,52(4):404-409 2015(Apr.)
Author:Motobayashi, Mitsuo; Inaba, Yuji; Nishimura, Takafumi; Kobayashi, Norimoto; Nakazawa, Yozo; Koike, Kenichi;


Safety and tolerability of allogeneic dendritic cell vaccination with induction of Wilms tumor 1-specific T cells in a pediatric donor and pediatric patient with relapsed leukemia: a case report and review of the literature
CYTOTHERAPY,17(3):330-335 2015(Mar.)
Author:Saito, Shoji; Yanagisawa, Ryu; Yoshikawa, Kentaro; Higuchi, Yumiko; Koya, Terutsugu; Yoshizawa, Kiyoshi; Tanaka, Miyuki; Sakashita, Kazuo; Kobayashi, Takashi; Kurata, Takashi; Hirabayashi, Koichi; Nakazawa, Yozo; Shiohara, Masaaki; Yonemitsu, Yoshikazu; Okamoto, Masato; Sugiyama, Haruo; Koike, Kenichi; Shimodaira, Shigetaka;


Successful treatment for West syndrome with severe combined immunodeficiency
BRAIN & DEVELOPMENT,37(1):140-144 2015(Jan.)
Author:Motobayashi, Mitsuo; Inaba, Yuji; Fukuyama, Tetsuhiro; Kurata, Takashi; Niimi, Taemi; Saito, Shoji; Shiba, Naoko; Nishimura, Takafumi; Shigemura, Tomonari; Nakazawa, Yozo; Kobayashi, Norimoto; Sakashita, Kazuo; Agematsu, Kazunaga; Ichikawa, Motoki; Koike, Kenichi;


Dramatic Improvement in the Multifocal Positron Emission Tomography Findings of a Young Adult with Chronic Granulomatous Disease Following Allogeneic Hematopoietic Stem Cell Transplantation
JOURNAL OF CLINICAL IMMUNOLOGY,35(1):84-86 2015(Jan.)
Author:Shigemura, Tomonari; Nakazawa, Yozo; Hirabayashi, Koichi; Kobayashi, Norimoto; Sakashita, Kazuo; Agematsu, Kazunaga; Koike, Kenichi;


Evaluation of Mucorales DNA load in cerebrospinal fluid in a patient with possible cerebral mucormycosis treated with intravenous liposomal amphotericin B
INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES,29:200-202 2014(Dec.)
Author:Shigemura, Tomonari; Nakazawa, Yozo; Matsuda, Kazuyuki; Motobayashi, Mitsuo; Saito, Shoji; Koike, Kenichi;


Anti-leukemic potency of piggyBac-mediated CD 19-specific T cells against refractory Philadelphia chromosome-positive acute lymphoblastic leukemia
CYTOTHERAPY,16(9):1257-1269 2014(Sep.)
Author:Saito, Shoji; Nakazawa, Yozo; Sueki, Akane; Matsuda, Kazuyuki; Tanaka, Miyuki; Yanagisawa, Ryu; Maeda, Yasuhiro; Sato, Yuko; Okabe, Seiichi; Inukai, Takeshi; Sugita, Kanji; Wilson, Matthew H.; Rooney, Cliona M.; Koike, Kenichi;


Serial monitoring of Mucorales DNA load in serum samples of a patient with disseminated mucormycosis after allogeneic bone marrow transplantation
INTERNATIONAL JOURNAL OF HEMATOLOGY,100(2):206-209 2014(Aug.)
Author:Shigemura, Tomonari; Nakazawa, Yozo; Matsuda, Kazuyuki; Sano, Kenji; Yaguchi, Takashi; Motobayashi, Mitsuo; Saito, Shoji; Noda, Shunsuke; Kobayashi, Norimoto; Agematsu, Kazunaga; Honda, Takayuki; Koike, Kenichi;


Risk factors for diabetes mellitus and impaired glucose tolerance following allogeneic hematopoietic stem cell transplantation in pediatric patients with hematological malignancies
INTERNATIONAL JOURNAL OF HEMATOLOGY,99(4):477-486 2014(Apr.)
Author:Hirabayashi, Kanae; Nakazawa, Yozo; Matsuura, Hiroki; Hara, Yosuke; Kurata, Takashi; Hirabayashi, Koichi; Saito, Shoji; Yoshikawa, Kentaro; Tanaka, Miyuki; Yanagisawa, Ryu; Sakashita, Kazuo; Koike, Kenichi;


Successful cord blood transplantation after repeated transfusions of unmobilized neutrophils in addition to antifungal treatment in an infant with chronic granulomatous disease complicated by invasive pulmonary aspergillosis
TRANSFUSION,54(3):516-521 2014(Mar.)
Author:Shigemura, Tomonari; Nakazawa, Yozo; Yoshikawa, Kentaro; Hirabayashi, Koichi; Saito, Shoji; Kobayashi, Norimoto; Sakashita, Kazuo; Shiohara, Masaaki; Wada, Taizo; Shimodaira, Shigetaka; Agematsu, Kazunaga; Koike, Kenichi;


Sustained elevation of serum interleukin-18 and its association with hemophagocytic lymphohistiocytosis in XIAP deficiency
CYTOKINE,65(1):74-78 2014(Jan.)
Author:Wada, Taizo; Kanegane, Hirokazu; Ohta, Kazuhide; Katoh, Fumiyo; Imamura, Toshihiko; Nakazawa, Yozo; Miyashita, Ritsuko; Hara, Junichi; Hamamoto, Kazuko; Yang, Xi; Filipovich, Alexandra H.; Marsh, Rebecca A.; Yachie, Akihiro;


Cytokine production profiles in chronic relapsing-remitting experimental autoimmune encephalomyelitis: IFN-gamma and TNF-alpha are important participants in the first attack but not in the relapse
JOURNAL OF THE NEUROLOGICAL SCIENCES,340(1-2):117-122 2014
Author:Hidaka, Yoshihiko; Inaba, Yuji; Matsuda, Kazuyuki; Itoh, Makoto; Kaneyama, Tomoki; Nakazawa, Yozo; Koh, Chang-Sung; Ichikawa, Motoki;


Reduced-toxicity myeloablative conditioning consisting of 8-Gy total body irradiation, cyclophosphamide and fludarabine for pediatric hematological malignancies
SCIENTIFIC REPORTS,4 2014
Author:Hirabayashi, Koichi; Nakazawa, Yozo; Sakashita, Kazuo; Kurata, Takashi; Saito, Shoji; Yoshikawa, Kentaro; Tanaka, Miyuki; Yanagisawa, Ryu; Koike, Kenichi;


Identification of a novel HLA-A*24:02-restricted adenovirus serotype 11-specific CD8(+) T-cell epitope for adoptive immunotherapy
MOLECULAR IMMUNOLOGY,56(4):399-405 2013(Dec.)
Author:Imahashi, Nobuhiko; Nishida, Tetsuya; Ito, Yoshinori; Kawada, Jun-ichi; Nakazawa, Yozo; Toji, Shingo; Suzuki, Susumu; Terakura, Seitaro; Kato, Tomonori; Murata, Makoto; Naoe, Tomoki;


Usefulness of Allogeneic Hematopoietic Stem Cell Transplantation in First Complete Remission for Pediatric Blastic Plasmacytoid Dendritic Cell Neoplasm With Skin Involvement: A Case Report and Review of Literature
PEDIATRIC BLOOD & CANCER,60(11):E140-E142 2013(Nov.)
Author:Sakashita, Kazuo; Saito, Shoji; Yanagisawa, Ryu; Tanaka, Miyuki; Yoshikawa, Kentaro; Hirabayashi, Koichi; Tsukahara, Keiko; Motobayashi, Mitsuo; Nakazawa, Yozo; Koike, Kenichi;


Replaced platelet concentrates containing a new additive solution, M-sol: safety and efficacy for pediatric patients
TRANSFUSION,53(9):2053-2060 2013(Sep.)
Author:Yanagisawa, Ryu; Shimodaira, Shigetaka; Kojima, Shunsuke; Nakasone, Nobuhiko; Ishikawa, Shinsuke; Momose, Kayo; Honda, Takayuki; Yoshikawa, Kentaro; Saito, Shoji; Tanaka, Miyuki; Nakazawa, Yozo; Sakashita, Kazuo; Shiohara, Masaaki; Akino, Mitsuaki; Hirayama, Junichi; Azuma, Hiroshi; Koike, Kenichi;


Evaluation of Long-term Transgene Expression in piggyBac-Modified Human T Lymphocytes
JOURNAL OF IMMUNOTHERAPY,36(1):3-10 2013(Jan.)
Author:Nakazawa, Yozo; Saha, Sunandan; Galvan, Daniel L.; Huye, Leslie; Rollins, Lisa; Rooney, Cliona M.; Wilson, Matthew H.;


piggyBac Transposon System Modification of Primary Human T Cells
JOVE-JOURNAL OF VISUALIZED EXPERIMENTS,(69) 2012(Nov.)
Author:Saha, Sunandan; Nakazawa, Yozo; Huye, Leslie E.; Doherty, Joseph E.; Galvan, Daniel L.; Rooney, Cliona M.; Wilson, Matthew H.;


Food allergy after cord blood transplantation in children
BRITISH JOURNAL OF HAEMATOLOGY,158(5):672-676 2012(Sep.)
Author:Sakashita, Kazuo; Nakazawa, Yozo; Yanagisawa, Ryu; Tanaka, Miyuki; Saito, Shoji; Yoshikawa, Kentaro; Hirabayashi, Koichi; Kusakari, Mai; Kato, Sawako; Hidaka, Nao; Nakayama, Yoshiko; Shigemura, Tomonari; Kobayashi, Norimoto; Kobayashi, Mikiko; Shiohara, Masaaki; Koike, Kenichi;


Clinical features and outcome of X-linked lymphoproliferative syndrome type 1 (SAP deficiency) in Japan identified by the combination of flow cytometric assay and genetic analysis
PEDIATRIC ALLERGY AND IMMUNOLOGY,23(5):488-493 2012(Aug.)
Author:Kanegane, Hirokazu; Yang, Xi; Zhao, Meina; Yamato, Kazumi; Inoue, Masami; Hamamoto, Kazuko; Kobayashi, Chie; Hosono, Ako; Ito, Yoshikiyo; Nakazawa, Yozo; Terui, Kiminori; Kogawa, Kazuhiro; Ishii, Eiichi; Sumazaki, Ryo; Miyawaki, Toshio;


Long-term haematological improvement after non-intensive or no chemotherapy in juvenile myelomonocytic leukaemia and poor correlation with adult myelodysplasia spliceosome-related mutations
BRITISH JOURNAL OF HAEMATOLOGY,157(5):647-650 2012(Jun.)
Author:Matsuda, Kazuyuki; Yoshida, Nao; Miura, Shuhei; Nakazawa, Yozo; Sakashita, Kazuo; Hyakuna, Nobuyuki; Saito, Masahiro; Kato, Fumiyo; Ogawa, Atsushi; Watanabe, Akihiro; Sotomatsu, Manabu; Kobayashi, Chie; Ito, Toshiro; Ishida, Fumihiro; Manabe, Atsushi; Kojima, Seiji; Koike, Kenichi;


Critical Illness Polyneuropathy and Myopathy Caused by Bacillus Cereus Sepsis in Acute Lymphoblastic Leukemia
JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY,34(3):E110-E113 2012(Apr.)
Author:Hirabayashi, Koichi; Shiohara, Masaaki; Suzuki, Takefumi; Saito, Shoji; Tanaka, Miyuki; Yanagisawa, Ryu; Tsuruta, Goro; Fukuyama, Tetsuhiro; Hidaka, Yoshihiko; Nakazawa, Yozo; Shimizu, Takashi; Sakashita, Kazuo; Koike, Kenichi;


Combining mTor Inhibitors With Rapamycin-resistant T Cells: A Two-pronged Approach to Tumor Elimination
MOLECULAR THERAPY,19(12):2239-2248 2011(Dec.)
Author:Huye, Leslie E.; Nakazawa, Yozo; Patel, Mayuri P.; Yvon, Eric; Sun, Jiali; Savoldo, Barbara; Wilson, Matthew H.; Dotti, Gianpietro; Rooney, Cliona M.;


Prophylactic treatment for hypertension and seizure in a case of allogeneic hematopoietic stem cell transplantation after posterior reversible encephalopathy syndrome
PEDIATRIC TRANSPLANTATION,15(8):E169-E173 2011(Dec.)
Author:Fukuyama, Tetsuhiro; Tanaka, Miyuki; Nakazawa, Yozo; Motoki, Noriko; Inaba, Yuji; Higuchi, Tsukasa; Koike, Kenichi;


Genetic analysis of TP53 in childhood myelodysplastic syndrome and juvenile myelomonocytic leukemia
LEUKEMIA RESEARCH,35(12):1578-1584 2011(Dec.)
Author:Saito, Shoji; Matsuda, Kazuyuki; Taira, Chiaki; Sano, Kenji; Tanaka-Yanagisawa, Miyuki; Yanagisawa, Ryu; Nakazawa, Yozo; Sakashita, Kazuo; Shiohara, Masaaki; Koike, Kenichi;


Telecommunication system for children undergoing stem cell transplantation
PEDIATRICS INTERNATIONAL,53(6):1002-1009 2011(Dec.)
Author:Higuchi, Kazumi; Nakazawa, Yozo; Sakata, Nobuhiro; Takizawa, Masaomi; Ohso, Keiko; Tanaka, Miyuki; Yanagisawa, Ryu; Koike, Kenichi;


PiggyBac-mediated Cancer Immunotherapy Using EBV-specific Cytotoxic T-cells Expressing HER2-specific Chimeric Antigen Receptor
MOLECULAR THERAPY,19(12):2133-2143 2011(Dec.)
Author:Nakazawa, Yozo; Huye, Leslie E.; Salsman, Vita S.; Leen, Ann M.; Ahmed, Nabil; Rollins, Lisa; Dotti, Gianpietro; Gottschalk, Stephen M.; Wilson, Matthew H.; Rooney, Cliona M.;


Disappearance of Minimal Residual Disease After the Early Withdrawal of Immunosuppressants in a Patient With Juvenile Myelomonocytic Leukemia
PEDIATRIC BLOOD & CANCER,56(3):501-502 2011(Mar.)
Author:Yanagisawa, Ryu; Matsuda, Kazuyuki; Sakashita, Kazuo; Nakazawa, Yozo; Tanaka, Miyuki; Saito, Shoji; Yoshikawa, Kentaro; Kamijo, Takehiko; Shiohara, Masaaki; Koike, Kenichi;


Early and Rapid Detection of X-Linked Lymphoproliferative Syndrome with SH2D1A Mutations by Flow Cytometry
CYTOMETRY PART B-CLINICAL CYTOMETRY,80B(1):8-13 2011(Jan.)
Author:Zhao, Meina; Kanegane, Hirokazu; Kobayashi, Chie; Nakazawa, Yozo; Ishii, Eizaburo; Kasai, Mikio; Terui, Kiminori; Gocho, Yoshihiro; Imai, Kohsuke; kiyasu, Junichi; Nonoyama, Shigeaki; Miyawaki, Toshio;


Detection of T-cell receptor gene rearrangement in children with Epstein-Barr virus-associated hemophagocytic lymphohistiocytosis using the BIOMED-2 multiplex polymerase chain reaction combined with GeneScan analysis
CLINICA CHIMICA ACTA,412(17-18):1554-1558 2011
Author:Matsuda, Kazuyuki; Nakazawa, Yozo; Yanagisawa, Ryu; Honda, Takayuki; Ishii, Eiichi; Koike, Kenichi;


Increased pretransplant QT dispersion as a risk factor for the development of cardiac complications during and after preparative conditioning for pediatric allogeneic hematopoietic stem cell transplantation
PEDIATRIC TRANSPLANTATION,14(8):986-992 2010(Dec.)
Author:Motoki, Noriko; Shimizu, Takashi; Akazawa, Yohei; Saito, Shoji; Tanaka, Miyuki; Yanagisawa, Ryu; Motoki, Hirohiko; Nakazawa, Yozo; Sakashita, Kazuo; Iwasaki, Yasushi; Shiohara, Masaaki; Koike, Kenichi;


Purification, Biochemical Characterization, and Cloning of Phospholipase D from Streptomyces racemochromogenes Strain 10-3
PROTEIN JOURNAL,29(8):598-608 2010(Nov.)
Author:Nakazawa, Yozo; Sagane, Yoshimasa; Kikuchi, Teppei; Uchino, Masataka; Nagai, Takeshi; Sato, Hiroaki; Toeda, Kazuki; Takano, Katsumi;


piggyBac Transposon/Transposase System to Generate CD19-Specific T Cells for the Treatment of B-Lineage Malignancies
HUMAN GENE THERAPY,21(4):427-437 2010(Apr.)
Author:Manuri, Pallavi V. Raja; Wilson, Matthew H.; Maiti, Sourindra N.; Mi, Tiejuan; Singh, Harjeet; Olivares, Simon; Dawson, Margaret J.; Huls, Helen; Lee, Dean A.; Rao, Pulivarthi H.; Kaminski, Joseph M.; Nakazawa, Yozo; Gottschalk, Stephen; Kebriaei, Partow; Shpall, Elizabeth J.; Champlin, Richard E.; Cooper, Laurence J. N.;


Long-term survival after nonintensive chemotherapy in some juvenile myelomonocytic leukemia patients with CBL mutations, and the possible presence of healthy persons with the mutations
BLOOD,115(26):5429-5431 2010
Author:Matsuda, Kazuyuki; Taira, Chiaki; Sakashita, Kazuo; Saito, Shoji; Tanaka-Yanagisawa, Miyuki; Yanagisawa, Ryu; Nakazawa, Yozo; Shiohara, Masaaki; Fukushima, Keitaro; Oda, Megumi; Honda, Takayuki; Nakahata, Tatsutoshi; Koike, Kenichi;


Polymyxin-Direct Hemoperfusion for Sepsis-Induced Multiple Organ Failure
PEDIATRIC BLOOD & CANCER,55(1):202-205 2010
Author:Hirabayashi, Koichi; Shiohara, Masaaki; Saito, Shoji; Tanaka, Miyuki; Yanagisawa, Ryu; Tsuruta, Goro; Fukuyama, Tetsuhiro; Hidaka, Yoshihiko; Nakazawa, Yozo; Shimizu, Takashi; Sakashita, Kazuo; Koike, Kenichi;


Optimization of the PiggyBac Transposon System for the Sustained Genetic Modification of Human T Lymphocytes
JOURNAL OF IMMUNOTHERAPY,32(8):826-836 2009(Oct.)
Author:Nakazawa, Yozo; Huye, Leslie E.; Dotti, Gianpietro; Foster, Aaron E.; Vera, Juan F.; Manuri, Pallavi R.; June, Carl H.; Rooney, Cliona M.; Wilson, Matthew H.;


Genome-wide Mapping of PiggyBac Transposon Integrations in Primary Human T Cells
JOURNAL OF IMMUNOTHERAPY,32(8):837-844 2009(Oct.)
Author:Galvan, Daniel L.; Nakazawa, Yozo; Kaja, Aparna; Kettlun, Claudia; Cooper, Laurence J. N.; Rooney, Cliona M.; Wilson, Matthew H.;


Low toxicity of a conditioning with 8-Gy total body irradiation, fludarabine and cyclophosphamide as preparative regimen for allogeneic hematopoietic stem cell transplantation in pediatric hematological malignancies
PEDIATRIC TRANSPLANTATION,13(6):737-745 2009(Sep.)
Author:Yanagisawa, Ryu; Nakazawa, Yozo; Sakashita, Kazuo; Tanaka, Miyuki; Shikama, Naoto; Kamijo, Takehiko; Shiohara, Masaaki; Koike, Kenichi;


Urinary excretion of ganciclovir contributes to improvement of adenovirus-associated hemorrhagic cystitis after allogeneic bone marrow transplantation
PEDIATRIC TRANSPLANTATION,13(5):632-635 2009(Aug.)
Author:Nakazawa, Yozo; Suzuki, Takefumi; Fukuyama, Tetsuhiro; Katsuyama, Yoshihiko; Tanaka, Miyuki; Yanagisawa, Ryu; Sakashita, Kazuo; Shiohara, Masaaki; Koike, Kenichi;


High incidence of meropenem resistance among alpha-hemolytic streptococci in children with cancer
PEDIATRICS INTERNATIONAL,51(1):103-106 2009(Feb.)
Author:Abe, Masako; Kamijo, Takehiko; Matsuzawa, Shigeyuki; Miki, Jun; Nakazawa, Yozo; Sakashita, Kazuo; Okabe, Tadashi; Honda, Takayuki; Mitsuyama, Jun-ichi; Koike, Kenichi;


A conditioning regimen of busulfan, fludarabine, and melphalan for allogeneic stem cell transplantation in children with juvenile myelomonocytic leukemia
PEDIATRIC TRANSPLANTATION,12(8):862-867 2008(Dec.)
Author:Yabe, Miharu; Sako, Masahiro; Yabe, Hiromasa; Osugi, Yuko; Kurosawa, Hidemitsu; Nara, Taemi; Tokuyama, Mika; Adachi, Souichi; Kobayashi, Chie; Yanagimachi, Masakatsu; Ohtsuka, Yoshitoshi; Nakazawa, Yozo; Ogawa, Chitose; Manabe, Atsushi; Kojima, Seiji; Nakahata, Tatsutoshi; Japanese Childhood MDS Study Grp;


Exploiting cytokine secretion to rapidly produce multivirus-specific T cells for adoptive immunotherapy
JOURNAL OF IMMUNOTHERAPY,31(7):665-674 2008(Sep.)
Author:Fujita, Yuriko; Leen, Ann M.; Sun, Jiali; Nakazawa, Yozo; Yvon, Eric; Heslop, Helen E.; Brenner, Malcohn K.; Rooney, Cliona M.;


Promising approach for aggressive NK cell leukaemia with allogeneic haematopoietic cell transplantation
EUROPEAN JOURNAL OF HAEMATOLOGY,81(2):107-111 2008(Aug.)
Author:Ito, Toshiro; Makishima, Hideki; Nakazawa, Hideyuki; Kobayashi, Hikaru; Shimodaira, Shigetaka; Nakazawa, Yozo; Kitano, Kiyoshi; Matsuda, Kazuyuki; Hidaka, Eiko; Ishida, Fumihiro;


Long-term Follow-up of Plasma Cells in Bone Marrow and Serum Free Light Chains in Primary Systemic AL Amyloidosis
INTERNAL MEDICINE,47(20):1783-1790 2008
Author:Yoshida, Takuhiro; Matsuda, Masayuki; Katoh, Nagaaki; Tazawa, Ko-ichi; Shimojima, Yasuhiro; Gono, Takahisa; Ishii, Wataru; Nakazawa, Yozo; Sakashita, Kazuo; Koike, Kenichi; Yamada, Toshiyuki; Ikeda, Shu-ichi;


Acquisition of loss of the wild-type NRAS locus with aggressive disease progression in a patient with juvenile myelomonocytic leukemia and a heterozygous NRAS mutation
HAEMATOLOGICA-THE HEMATOLOGY JOURNAL,92(11):1576-1578 2007(Nov.)
Author:Matsuda, Kazuyuki; Nakazawa, Yozo; Sakashita, Kazuo; Shiohara, Masaaki; Yamauchi, Kazuyoshi; Koike, Kenichi;


Chemokine system and tissue infiltration in aggressive NK-cell leukemia
LEUKEMIA RESEARCH,31(9):1237-1245 2007(Sep.)
Author:Makishima, Hideki; Ito, Toshiro; Momose, Kayoko; Nakazawa, Hideyuki; Shimodaira, Shigetaka; Kamijo, Yuji; Nakazawa, Yozo; Ichikawa, Naoaki; Ueno, Mayumi; Kobayashi, Hikaru; Kitano, Kiyoshi; Saito, Hiroshi; Kiyosawa, Kendo; Ishida, Fumihiro;


Outcome of non-T-cell-depleted HLA-haploidentical hematopoietic stem cell transplantation from family donors in children and adolescents
INTERNATIONAL JOURNAL OF HEMATOLOGY,85(3):246-255 2007(Apr.)
Author:Yoshihara, Takao; Okada, Keiko; Kobayashi, Michihiro; Kikuta, Atsushi; Kato, Koji; Adachi, Naoto; Kikuchi, Akira; Ishida, Hiroyuki; Hirota, Yasuzou; Kuroda, Hiroshi; Nagatoshi, Yoshihisa; Inukai, Takeshi; Koike, Kazutoshi; Kigasawa, Hisato; Yagasaki, Hiroshi; Tokuda, Kiriko; Kishimoto, Tomoko; Nakano, Takahide; FJjita, Naoto; Goto, Hiroaki; Nakazawa, Yozo; Kanegane, Hirokazu; Matsuzaki, Akinobu; Osugi, Yuko; Hasegawa, Daiichiro; Uoshima, Nobuhiko; Nakamura, Kazuhiro; Tsuchida, Masahiro; Tanaka, Ryuhei; Watanabe, Arata; Yabe, Hiromasa;


A possible role for the production of multiple HLA antibodies in fatal platelet transfusion refractoriness after peripheral blood progenitor cell transplantation from the mother in a patient with relapsed leukemia
TRANSFUSION,47(2):326-334 2007(Feb.)
Author:Nakazawa, Yozo; Saito, Satoshi; Hasegawa, Yasuhisa; Yanagisawa, Ryu; Sakashita, Kazuo; Kamijo, Takehiko; Miyazaki, Toru; Sato, Shinichiro; Ikeda, Hisami; Ikebuchi, Kenji; Koike, Kenichi;


Spontaneous improvement of hematologic abnormalities in patients having juvenile myelomonocytic leukemia with specific RAS mutations
BLOOD,109(12):5477-5480 2007
Author:Matsuda, Kazuyuki; Shimada, Akira; Yoshida, Nao; Ogawa, Atsushi; Watanabe, Akihiro; Yajima, Shuhei; Iizuka, Susumu; Koike, Kazutoshi; Yanai, Fumio; Kawasaki, Keiichiro; Yanagimachi, Masakatsu; Kikuchi, Akira; Ohtsuka, Yoshitoshi; Hidaka, Eiko; Yamauchi, Kazuyoshi; Tanaka, Miyuki; Yanagisawa, Ryu; Nakazawa, Yozo; Shiohara, Masaaki; Manabe, Atsushi; Kojima, Seiji; Koike, Kenichi;


A complex karyotype, including a three-way translocation generating a NUP98-HOXD13 transcript, in an infant with acute myeloid leukemia
CANCER GENETICS AND CYTOGENETICS,176(2):137-143 2007
Author:Hidaka, Eiko; Tanaka, Miyuki; Matsuda, Kazuyuki; Ishikawa-Matsumura, Masayo; Yamauchi, Kazuyoshi; Sano, Kenji; Honda, Takayuki; Wakui, Keiko; Yanagisawa, Ryu; Nakazawa, Yozo; Sakashita, Kazuo; Shiohara, Masaaki; Ishii, Eizaburo; Koike, Kenichi;

研究費
受託研究
2018 - 2023 , 日本発の遺伝子改変T細胞の実用化を促進するための、霊長類モデルを用いた安全性評価系の基盤整備
2017 - 2019 , CD116陽性骨髄系腫瘍を標的とした非ウイルス遺伝子改変キメラ抗原受容体T細胞の非臨床試験

科学研究費補助金(研究代表者)
2017 - 2019 , 再発・治療不応性T細胞性白血病に対するキメラ抗原受容体T細胞療法の開発 , 基盤研究(C)
2014 - 2016 , 難治性急性骨髄性白血病に対するFLT3を標的とした遺伝子改変T細胞療法の開発 , 基盤研究(C)
2011 - 2013 , 進行性神経芽腫に対するGD2特異的キメラ抗原受容体を用いた遺伝子改変T細胞療法 , 基盤研究(C)
2005 - 2006 , 若年性骨髄単球性白血病におけるポリコーム遺伝子による癌抑制経路不活化機構の解析 , 若手研究(B)