博士（医学）, 信州大学

エネルギー代謝におけるＧタンパク質共役型受容体（GPCR）シグナルの重要性
木村 岳史
信州医学雑誌, 70(4), 213-223, 2022年08月

Expression and Role of beta 3-Adrenergic Receptor during the Differentiation of 3T3-L1 Preadipocytes into Adipocytes
Roshanzadeh, Amir; Yadav, Anil Kumar; Pydi, Sai-Prasad; Kimura, Takefumi; Jang, Byeong-Churl;
BIOLOGY-BASEL, 11(5), 772, 2022年05月

2-Step PLT16-AST44 method: Simplified liver fibrosis detection system in patients with non-alcoholic fatty liver disease
Fujimori, Naoyuki; Kimura, Takefumi; Tanaka, Naoki; Yamazaki, Tomoo; Okumura, Taiki; Kobayashi, Hiroyuki; Wakabayashi, Shun-Ichi; Yamashita, Yuki; Sugiura, Ayumi; Pham, Jonathan; Pydi, Sai P.; Sano, Kenji; Joshita, Satoru; Umemura, Takeji;
HEPATOLOGY RESEARCH, 52(4), 352-363, 2022年04月

Adipocyte G(q) signaling is a regulator of glucose and lipid homeostasis in mice
Kimura, Takefumi; Pydi, Sai P.; Wang, Lei; Haspula, Dhanush; Cui, Yinghong; Lu, Huiyan; Koenig, Gabriele M.; Kostenis, Evi; Steinberg, Gregory R.; Gavrilova, Oksana; Wess, Juergen;
NATURE COMMUNICATIONS, 13(1), 1652, 2022年

Acidic Activated Charcoal Prevents Obesity and Insulin Resistance in High-Fat Diet-Fed Mice
Zhang, Xuguang; Diao, Pan; Yokoyama, Hiroaki; Inoue, Yoshiki; Tanabe, Kazuhiro; Wang, Xiaojing; Hayashi, Chihiro; Yokoyama, Tomoki; Zhang, Zhe; Hu, Xiao; Nakajima, Takero; Kimura, Takefumi; Nakayama, Jun; Nakamuta, Makoto; Tanaka, Naoki;
Frontiers in Nutrition, 9, 852767, 2022年

Mechanisms of Steatosis-Derived Hepatocarcinogenesis: Lessons from HCV Core Gene Transgenic Mice
Diao, Pan; Jia, Fangping; Wang, Xiaojing; Hu, Xiao; Kimura, Takefumi; Nakajima, Takero; Aoyama, Toshifumi; Moriya, Kyoji; Koike, Kazuhiko; Tanaka, Naoki;
ENGINEERING, 7(12), 1797-1805, 2021年12月

Impact of Dietary Fat on the Progression of Liver Fibrosis: Lessons from Animal and Cell Studies
Jia, Fangping; Hu, Xiao; Kimura, Takefumi; Tanaka, Naoki;
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 22(19), 10303, 2021年10月

Receptor-Mediated Gq Signaling in Adipocytes as a Critical Modulator of Systemic Glucose and Lipid Homeostasis
Kimura, Takefumi; Pydi, Sai Prasad; Wang, Lei; Cui, Yinghong; Gavrilova, Oksana; Wess, Jurgen;
DIABETES, 70, 2021年06月

G(q) signaling in adipocytes is a key regulator of systemic glucose and lipid homeostasis
Kimura, Takefumi; Pydi, Sai; Wang, Lei; Cui, Yinghong; Gavrilova, Oksana; Wess, Jurgen;
FASEB JOURNAL, 35, 2021年05月

Metabolic roles of G protein-coupled receptor signaling in obesity and type 2 diabetes
Barella, Luiz F.; Jain, Shanu; Kimura, Takefumi; Pydi, Sai P.;
FEBS JOURNAL, 288(8), 2622-2644, 2021年04月

Serum thrombospondin 2 is a novel predictor for the severity in the patients with NAFLD
Kimura, Takefumi; Tanaka, Naoki; Fujimori, Naoyuki; Yamazaki, Tomoo; Katsuyama, Takahito; Iwashita, Yuichi; Pham, Jonathan; Joshita, Satoru; Pydi, Sai P.; Umemura, Takeji;
LIVER INTERNATIONAL, 41(3), 505-514, 2021年03月

Role of G Protein-Coupled Receptors in Hepatic Stellate Cells and Approaches to Anti-Fibrotic Treatment of Non-Alcoholic Fatty Liver Disease
Kimura, Takefumi; Singh, Simran; Tanaka, Naoki; Umemura, Takeji;
FRONTIERS IN ENDOCRINOLOGY, 12, 773432, 2021年

Susceptibility of the obese population to COVID-19
Kimura, Takefumi; Namkoong, Ho;
INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES, 101, 380-381, 2020年12月

A saturated fatty acid-rich diet enhances hepatic lipogenesis and tumorigenesis in HCV core gene transgenic mice
Diao, Pan; Wang, Xiaojing; Jia, Fangping; Kimura, Takefumi; Hu, Xiao; Shirotori, Saki; Nakamura, Ibuki; Sato, Yoshiko; Nakayama, Jun; Moriya, Kyoji; Koike, Kazuhiko; Gonzalez, Frank J.; Aoyama, Toshifumi; Tanaka, Naoki;
JOURNAL OF NUTRITIONAL BIOCHEMISTRY, 85, 108460, 2020年11月

Metabolic Functions of G Protein-Coupled Receptors in Hepatocytes-Potential Applications for Diabetes and NAFLD
Kimura, Takefumi; Pydi, Sai P.; Pham, Jonathan; Tanaka, Naoki;
BIOMOLECULES, 10(10), 1445, 2020年10月

Acute liver failure with severe steatosis induced by mushroom
Wakabayashi, Shun-ichi; Kimura, Takefumi; Tanaka, Naoki;
LIVER INTERNATIONAL, 40(9), 2291-2292, 2020年09月

Dietary Restriction Suppresses Steatosis-Associated Hepatic Tumorigenesis in Hepatitis C Virus Core Gene Transgenic Mice
Jia, Fangping; Diao, Pan; Wang, Xiaojing; Hu, Xiao; Kimura, Takefumi; Nakamuta, Makoto; Nakamura, Ibuki; Shirotori, Saki; Sato, Yoshiko; Moriya, Kyoji; Koike, Kazuhiko; Gonzalez, Frank J.; Nakayama, Jun; Aoyama, Toshifumi; Tanaka, Naoki;
Liver Cancer, 9(5), 529-548, 2020年09月

Activation of Adipocyte Gq Signaling Causes Improved Whole-Body Glucose Homeostasis
Kimura, Takefumi; Pydi, Sai Prasad; Wang, Lei; Cui, Yinghong; Gavrilova, Oksana; Wess, Jurgen;
DIABETES, 69, 2020年06月

Effectiveness of Glecaprevir/Pibrentasvir for Hepatitis C: Real-World Experience and Clinical Features of Retreatment Cases
Sugiura, Ayumi; Joshita, Satoru; Yamashita, Yuki; Yamazaki, Tomoo; Fujimori, Naoyuki; Kimura, Takefumi; Matsumoto, Akihiro; Wada, Shuichi; Mori, Hiromitsu; Shibata, Soichiro; Yoshizawa, Kaname; Morita, Susumu; Furuta, Kiyoshi; Kamijo, Atsushi; Iijima, Akihiro; Kako, Satoko; Maruyama, Atsushi; Kobayashi, Masakazu; Komatsu, Michiharu; Matsumura, Makiko; Miyabayashi, Chiharu; Ichijo, Tetsuya; Takeuchi, Aki; Koike, Yuriko; Gibo, Yukio; Tsukadaira, Toshihisa; Inada, Hiroyuki; Nakano, Yoshiyuki; Usuda, Seiichi; Kiyosawa, Kendo; Tanaka, Eiji; Umemura, Takeji;
BIOMEDICINES, 8(4), 74, 2020年04月

A trans-fatty acid-rich diet promotes liver tumorigenesis in HCV core gene transgenic mice
Hu, Xiao; Wang, Xiaojing; Jia, Fangping; Tanaka, Naoki; Kimura, Takefumi; Nakajima, Takero; Sato, Yoshiko; Moriya, Kyoji; Koike, Kazuhiko; Gonzalez, Frank J.; Nakayama, Jun; Aoyama, Toshifumi;
CARCINOGENESIS, 41(2), 159-170, 2020年02月

What will happen in patients with advanced nonalcoholic fatty liver disease?
Kimura, Takefumi; Tanaka, Naoki; Tanaka, Eiji;
HEPATOBILIARY SURGERY AND NUTRITION, 8(3), 283-285, 2019年06月

A high-cholesterol diet promotes steatohepatitis and liver tumorigenesis in HCV core gene transgenic mice (vol, pg, )
Wang, Xiaojing; Tanaka, Naoki; Hu, Xiao; Kimura, Takefumi; Lu, Yu; Jia, Fangping; Sato, Yoshiko; Nakayama, Jun; Moriya, Kyoji; Koike, Kazuhiko; Aoyama, Toshifumi;
ARCHIVES OF TOXICOLOGY, 93(6), 1727-1728, 2019年06月

A high-cholesterol diet promotes steatohepatitis and liver tumorigenesis in HCV core gene transgenic mice
Wang, Xiaojing; Tanaka, Naoki; Hu, Xiao; Kimura, Takefumi; Lu, Yu; Jia, Fangping; Sato, Yoshiko; Nakayama, Jun; Moriya, Kyoji; Koike, Kazuhiko; Aoyama, Toshifumi;
ARCHIVES OF TOXICOLOGY, 93(6), 1713-1725, 2019年06月

Red plasma and ascites under ultraviolet A
Wakabayashi, Shun-ichi; Kimura, Takefumi; Tanaka, Naoki; Komatsu, Michiharu; Tanaka, Eiji;
LANCET GASTROENTEROLOGY & HEPATOLOGY, 4(4), 324-324, 2019年04月

Current status, problems, and perspectives of non-alcoholic fatty liver disease research
Tanaka, Naoki; Kimura, Takefumi; Fujimori, Naoyuki; Nagaya, Tadanobu; Komatsu, Michiharu; Tanaka, Eiji;
WORLD JOURNAL OF GASTROENTEROLOGY, 25(2), 163-177, 2019年

Past history of hepatocellular carcinoma is an independent risk factor of treatment failure in patients with chronic hepatitis C virus infection receiving direct-acting antivirals
Sugiura, Ayumi; Joshita, Satoru; Umemura, Takeji; Yamazaki, Tomoo; Fujimori, Naoyuki; Kimura, Takefumi; Matsumoto, Akihiro; Igarashi, Koji; Usami, Yoko; Wada, Shuichi; Mori, Hiromitsu; Shibata, Soichiro; Yoshizawa, Kaname; Morita, Susumu; Furuta, Kiyoshi; Kamijo, Atsushi; Iijima, Akihiro; Kako, Satoko; Maruyama, Atsushi; Kobayashi, Masakazu; Komatsu, Michiharu; Matsumura, Makiko; Miyabayashi, Chiharu; Ichijo, Tetsuya; Takeuchi, Aki; Koike, Yuriko; Gibo, Yukio; Tsukadaira, Toshihisa; Inada, Hiroyuki; Kiyosawa, Kendo; Tanaka, Eiji;
JOURNAL OF VIRAL HEPATITIS, 25(12), 1462-1471, 2018年12月

Miglitol attenuates non-alcoholic steatohepatitis in diabetic patients
Komatsu, Michiharu; Tanaka, Naoki; Kimura, Takefumi; Fujimori, Naoyuki; Sano, Kenji; Horiuchi, Akira; Sugiura, Ayumi; Yamazaki, Tomoo; Shibata, Soichiro; Joshita, Satoru; Umemura, Takeji; Matsumoto, Akihiro; Tanaka, Eiji;
HEPATOLOGY RESEARCH, 48(13), 1092-1098, 2018年12月

THE RELATIONSHIP BETWEEN SERUM AUTOTAXIN LEVELS AND LIVER HISTOLOGICAL FINDINGS IN PATIENT WITH NON-ALCOHOLIC FATTY LIVER DISEASE
Fujimori, Naoyuki; Kimura, Takefumi; Tanaka, Naoki;
GASTROENTEROLOGY, 154(6), S1171-S1171, 2018年05月

長期経過加療中の非肝硬変期に肝細胞癌を合併した原発性胆汁性胆管炎の２例
杉浦 亜弓, 城下 智, 山下 裕騎, 木村 岳史, 山崎 智生, 藤森 尚之, 小松 通治, 松本 晶博, 小林 翔太, 梅村 武司, 田中 榮司
信州医学雑誌, 66(1), 39-49, 2018年02月

Serum Autotaxin Is a Useful Disease Progression Marker in Patients with Primary Biliary Cholangitis
Joshita, Satoru; Umemura, Takeji; Usami, Yoko; Yamashita, Yuki; Norman, Gary L.; Sugiura, Ayumi; Yamazaki, Tomoo; Fujimori, Naoyuki; Kimura, Takefumi; Matsumoto, Akihiro; Igarashi, Koji; Yoshizawa, Kaname; Ota, Masao; Tanaka, Eiji;
SCIENTIFIC REPORTS, 8, 8159, 2018年

Changes in serum levels of autotaxin with direct-acting antiviral therapy in patients with chronic hepatitis C
Yamazaki, Tomoo; Joshita, Satoru; Umemura, Takeji; Usami, Yoko; Sugiura, Ayumi; Fujimori, Naoyuki; Kimura, Takefumi; Matsumoto, Akihiro; Igarashi, Koji; Ota, Masao; Tanaka, Eiji;
PLOS ONE, 13(4), e0195632, 2018年

Hepatic Angiosarcoma with Kasabach-Merritt Phenomenon: A Case Report and Review of the Literature
Fujii, Fumika; Kimura, Takefumi; Tanaka, Naoki; Kubota, Daisuke; Sugiura, Ayumi; Umemura, Takeji; Wada, Shuichi; Tanaka, Eiji;
ANNALS OF HEPATOLOGY, 17(4), 655-660, 2018年

Mild drinking habit is a risk factor for hepatocarcinogenesis in non-alcoholic fatty liver disease with advanced fibrosis
Kimura, Takefumi; Tanaka, Naoki; Fujimori, Naoyuki; Sugiura, Ayumi; Yamazaki, Tomoo; Joshita, Satoru; Komatsu, Michiharu; Umemura, Takeji; Matsumoto, Akihiro; Tanaka, Eiji;
WORLD JOURNAL OF GASTROENTEROLOGY, 24(13), 1440-1450, 2018年

Serum autotaxin levels are correlated with hepatic fibrosis and ballooning in patients with non-alcoholic fatty liver disease
Fujimori, Naoyuki; Umemura, Takeji; Kimura, Takefumi; Tanaka, Naoki; Sugiura, Ayumi; Yamazaki, Tomoo; Joshita, Satoru; Komatsu, Michiharu; Usami, Yoko; Sano, Kenji; Igarashi, Koji; Matsumoto, Akihiro; Tanaka, Eiji;
WORLD JOURNAL OF GASTROENTEROLOGY, 24(11), 1239-1249, 2018年

Two cases of non-cirrhotic primary biliary cirrhosis with complicating hepatocellular carcinoma
Sugiura, Ayumi; Joshita, Satoru; Yamashita, Yuki; Hihara, Yu; Fujimori, Naoyuki; Yamazaki, Tomoo; Maruyama, Yasuhiro; Shibata, Souichiro; Ichikawa, Yuki; Kimura, Takefumi; Ito, Tetsuya; Komatsu, Michiharu; Umemura, Takeji; Matsumoto, Akihiro; Tanaka, Eiji;
JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 32, 186-186, 2017年09月

Association between lower air pressure and the onset of ischemic colitis: a case-control study
Kimura, Takefumi; Shinji, Akihiro; Tanaka, Naoki; Koinuma, Masayoshi; Yamaura, Maki; Nagaya, Tadanobu; Joshita, Satoru; Komatsu, Michiharu; Umemura, Takeji; Horiuchi, Akira; Wada, Shuichi; Tanaka, Eiji;
EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY, 29(9), 1071-1078, 2017年09月

ASSOCIATION BETWEEN LOWER AIR PRESSURE AND THE ONSET OF ISCHEMIC COLITIS: A NOVEL METEOROLOGICAL ASPECT
Kimura, Takefumi; Tanaka, Naoki;
GASTROENTEROLOGY, 152(5), S945-S945, 2017年04月

Clinicopathological characteristics of non-B non-C hepatocellular carcinoma without past hepatitis B virus infection
Kimura, Takefumi; Kobayashi, Akira; Tanaka, Naoki; Sano, Kenji; Komatsu, Michiharu; Fujimori, Naoyuki; Yamazaki, Tomoo; Shibata, Soichiro; Ichikawa, Yuki; Joshita, Satoru; Umemura, Takeji; Matsumoto, Akihiro; Horiuchi, Akira; Mori, Hiromitsu; Wada, Shuichi; Kiyosawa, Kendo; Miyagawa, Shin-ichi; Tanaka, Eiji;
HEPATOLOGY RESEARCH, 47(5), 405-418, 2017年04月

Vonoprazan-Based Regimen Is More Useful than PPI-Based One as a First-Line Helicobacter pylori Eradication: A Randomized Controlled Trial
Maruyama, Masafumi; Tanaka, Naoki; Kubota, Daisuke; Miyajima, Masayuki; Kimura, Takefumi; Tokutake, Koujiro; Imai, Ryujiro; Fujisawa, Toru; Mori, Hiromitsu; Matsuda, Yoshiaki; Wada, Shuichi; Horiuchi, Akira; Kiyosawa, Kendo;
CANADIAN JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 2017, 4385161, 2017年

Association between endotoxemia and histological features of nonalcoholic fatty liver disease
Kitabatake, Hiroyuki; Tanaka, Naoki; Fujimori, Naoyuki; Komatsu, Michiharu; Okubo, Ayaka; Kakegawa, Kyogo; Kimura, Takefumi; Sugiura, Ayumi; Yamazaki, Tomoo; Shibata, Soichiro; Ichikawa, Yuki; Joshita, Satoru; Umemura, Takeji; Matsumoto, Akihiro; Koinuma, Masayoshi; Sano, Kenji; Aoyama, Toshifumi; Tanaka, Eiji;
WORLD JOURNAL OF GASTROENTEROLOGY, 23(4), 712-722, 2017年

Controlled attenuation parameter is correlated with actual hepatic fat content in patients with non-alcoholic fatty liver disease with none-to-mild obesity and liver fibrosis
Fujimori, Naoyuki; Tanaka, Naoki; Shibata, Soichiro; Sano, Kenji; Yamazaki, Tomoo; Sekiguchi, Tomohiro; Kitabatake, Hiroyuki; Ichikawa, Yuki; Kimura, Takefumi; Komatsu, Michiharu; Umemura, Takeji; Matsumoto, Akihiro; Tanaka, Eiji;
HEPATOLOGY RESEARCH, 46(10), 1019-1027, 2016年09月

Liver stiffness-spleen size-to-platelet ratio risk score identifies esophageal varices in Japanese patients with chronic hepatitis C
Shibata, Soichiro; Umemura, Takeji; Yamazaki, Tomoo; Fujimori, Naoyuki; Ichikawa, Yuki; Kimura, Takefumi; Joshita, Satoru; Komatsu, Michiharu; Matsumoto, Akihiro; Tanaka, Eiji;
HEPATOLOGY RESEARCH, 46(9), 884-889, 2016年08月

A Randomized Controlled Trial Comparing the First-Line Eradication Rate Using Vonoprazan or PPI for Helicobacter pylori Infectious Gastritis
Maruyama, Masafumi; Kubota, Daisuke; Miyajima, Masayuki; Kimura, Takefumi; Tokutake, Koujiro; Imai, Ryujiro; Fujisawa, Toru; Mori, Hiromitsu; Matsuda, Yoshiaki; Wada, Shuichi; Kiyosawa, Kendo;
GASTROENTEROLOGY, 150(4), S1269-S1269, 2016年04月

Primary hepatocellular carcinoma in a patient with neurofibromatosis type I
Kimura, Takefumi; Tanaka, Naoki; Umemura, Takeji; Tanaka, Eiji;
LIVER INTERNATIONAL, 35(8), 2057-2058, 2015年08月

Serum sodium concentration is associated with increased risk of mortality in patients with compensated liver cirrhosis
Umemura, Takeji; Shibata, Soichiro; Sekiguchi, Tomohiro; Kitabatake, Hiroyuki; Nozawa, Yuichi; Okuhara, Sadahisa; Kimura, Takefumi; Morita, Susumu; Komatsu, Michiharu; Matsumoto, Akihiro; Tanaka, Eiji;
HEPATOLOGY RESEARCH, 45(7), 739-744, 2015年07月

Serum Wisteria floribunda Agglutinin-Positive Mac-2-Binding Protein Level Predicts Liver Fibrosis and Prognosis in Primary Biliary Cirrhosis
Umemura, Takeji; Joshita, Satoru; Sekiguchi, Tomohiro; Usami, Yoko; Shibata, Soichiro; Kimura, Takefumi; Komatsu, Michiharu; Matsumoto, Akihiro; Ota, Masao; Tanaka, Eiji;
AMERICAN JOURNAL OF GASTROENTEROLOGY, 110(6), 857-864, 2015年06月

Steatogenesis in adult-onset type II citrullinemia is associated with down-regulation of PPAR alpha
Komatsu, Michiharu; Kimura, Takefumi; Yazaki, Masahide; Tanaka, Naoki; Yang, Yang; Nakajima, Takero; Horiuchi, Akira; Fang, Zhong-Ze; Joshita, Satoru; Matsumoto, Akihiro; Umemura, Takeji; Tanaka, Eiji; Gonzalez, Frank J.; Ikeda, Shu-Ichi; Aoyama, Toshifumi;
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE, 1852(3), 473-481, 2015年03月

Serum Cell Death Biomarkers for Prediction of Liver Fibrosis and Poor Prognosis in Primary Biliary Cirrhosis
Sekiguchi, Tomohiro; Umemura, Takeji; Fujimori, Naoyuki; Shibata, Soichiro; Ichikawa, Yuki; Kimura, Takefumi; Joshita, Satoru; Komatsu, Michiharu; Matsumoto, Akihiro; Tanaka, Eiji; Ota, Masao;
PLOS ONE, 10(6), e0131658, 2015年

Mutations of pre-core and basal core promoter before and after hepatitis B e antigen seroconversion
Kamijo, Nozomi; Matsumoto, Akihiro; Umemura, Takeji; Shibata, Soichiro; Ichikawa, Yuki; Kimura, Takefumi; Komatsu, Michiharu; Tanaka, Eiji;
WORLD JOURNAL OF GASTROENTEROLOGY, 21(2), 541-548, 2015年

Characteristics and prediction of hepatitis B e-antigen negative hepatitis following seroconversion in patients with chronic hepatitis B
Morita, Susumu; Matsumoto, Akihiro; Umemura, Takeji; Shibata, Soichiro; Kamijo, Nozomi; Ichikawa, Yuki; Kimura, Takefumi; Joshita, Satoru; Komatsu, Michiharu; Yoshizawa, Kaname; Tanaka, Eiji;
HEPATOLOGY RESEARCH, 44(10), E45-E53, 2014年10月

Serum levels of interleukin-22 and hepatitis B core-related antigen are associated with treatment response to entecavir therapy in chronic hepatitis B
Okuhara, Sadahisa; Umemura, Takeji; Joshita, Satoru; Shibata, Soichiro; Kimura, Takefumi; Morita, Susumu; Komatsu, Michiharu; Matsumoto, Akihiro; Yoshizawa, Kaname; Katsuyama, Yoshihiko; Ota, Masao; Tanaka, Eiji;
HEPATOLOGY RESEARCH, 44(10), E172-E180, 2014年10月

KIR3DL1-HLA-Bw4 combination and IL28B polymorphism predict response to Peg-IFN and ribavirin with and without telaprevir in chronic hepatitis C
Umemura, Takeji; Ota, Masao; Katsuyama, Yoshihiko; Wada, Shuichi; Mori, Hiromitsu; Maruyama, Atsushi; Shibata, Soichiro; Nozawa, Yuichi; Kimura, Takefumi; Morita, Susumu; Joshita, Satoru; Komatsu, Michiharu; Matsumoto, Akihiro; Kamijo, Atsushi; Kobayashi, Masakazu; Takamatsu, Masato; Yoshizawa, Kaname; Kiyosawa, Kendo; Tanaka, Eiji;
HUMAN IMMUNOLOGY, 75(8), 822-826, 2014年08月

Laparoscopic findings of congenital hepatic fibrosis: A case report and review of the published work
Komatsu, Michiharu; Tanaka, Naoki; Shibata, So-Ichirou; Kimura, Takefumi; Ichikawa, Yuki; Morita, Susumu; Joshita, Satoru; Nagaya, Tadanobu; Umemura, Takeji; Ichijo, Tetsuya; Matsumoto, Akihiro; Yoshizawa, Kaname; Tanaka, Eiji;
HEPATOLOGY RESEARCH, 44(7), 818-824, 2014年07月

Natural History and Prognosis of Asymptomatic and Symptomatic Japanese Patients With Primary Biliary Cirrhosis: Results of a Median 9-Year Follow-Up Study
Joshita, Satoru; Umemura, Takeji; Nozawa, Yuichi; Okuhara, Sadahisa; Shibata, Soichiro; Kimura, Takefumi; Morita, Susumu; Komatsu, Michiharu; Matsumoto, Akihiro; Yoshizawa, Kaname; Ota, Masao; Tanaka, Eiji;
GASTROENTEROLOGY, 146(5), S906-S906, 2014年05月

Human Leukocyte Antigen Class II Haplotypes Affect Clinical Characteristics and Progression of Type 1 Autoimmune Hepatitis in Japan
Umemura, Takeji; Katsuyama, Yoshihiko; Yoshizawa, Kaname; Kimura, Takefumi; Joshita, Satoru; Komatsu, Michiharu; Matsumoto, Akihiro; Tanaka, Eiji; Ota, Masao;
PLOS ONE, 9(6), e100565, 2014年

Steatogenesis in adult-onset type II citrullinemia is associated with down-regulation of PPAR alpha
Kimura, Takefumi;
Hepatology, 60, 819A-819A, 2014年

STAT4 Gene Polymorphisms Are Associated with Susceptibility and ANA Status in Primary Biliary Cirrhosis
Joshita, Satoru; Umemura, Takeji; Nakamura, Minoru; Katsuyama, Yoshihiko; Shibata, Soichiro; Kimura, Takefumi; Morita, Susumu; Komatsu, Michiharu; Matsumoto, Akihiro; Yoshizawa, Kaname; Ishibashi, Hiromi; Tanaka, Eiji; Ota, Masao;
DISEASE MARKERS, 2014, 727393, 2014年

Peroxisome proliferator-activated receptor alpha mediates enhancement of gene expression of cerebroside sulfotransferase in several murine organs
Nakajima, Takero; Kamijo, Yuji; Huang Yuzhe; Kimura, Takefumi; Tanaka, Naoki; Sugiyama, Eiko; Nakamura, Kozo; Kyogashima, Mamoru; Hara, Atsushi; Aoyama, Toshifumi;
GLYCOCONJUGATE JOURNAL, 30(6), 553-560, 2013年08月

Cutaneous sarcoidosis in a chronic hepatitis C patient receiving pegylated interferon and ribavirin therapy
Joshita, Satoru; Shirahata, Kumiko; Yazaki, Yoshikazu; Okaniwa, Shinji; Nakamura, Yoshiyuki; Kimura, Takefumi; Noami, Sugiko; Horigome, Reiko; Yagi, Hikaru; Ito, Nobuo; Yamazaki, Asami; Akahane, Yuki; Umemura, Takeji; Yoshizawa, Kaname; Tanaka, Eiji; Ota, Masao;
HEPATOLOGY RESEARCH, 43(7), 801-807, 2013年07月

Association analysis of toll-like receptor 4 polymorphisms in Japanese primary biliary cirrhosis
Morita, Susumu; Joshita, Satoru; Umemura, Takeji; Katsuyama, Yoshihiko; Kimura, Takefumi; Komatsu, Michiharu; Matsumoto, Akihiro; Yoshizawa, Kaname; Kamijo, Astushi; Yamamura, Nobuyoshi; Tanaka, Eiji; Ota, Masao;
HUMAN IMMUNOLOGY, 74(2), 219-222, 2013年02月

KIR, HLA, and IL28B Variant Predict Response to Antiviral Therapy in Genotype 1 Chronic Hepatitis C Patients in Japan
Nozawa, Yuichi; Umemura, Takeji; Joshita, Satoru; Katsuyama, Yoshihiko; Shibata, Soichiro; Kimura, Takefumi; Morita, Susumu; Komatsu, Michiharu; Matsumoto, Akihiro; Tanaka, Eiji; Ota, Masao;
PLOS ONE, 8(12), e83381, 2013年

Clinical characteristics of young-onset ischemic colitis
Kimura, Takefumi; Shinji, Akihiro; Horiuchi, Akira; Tanaka, Naoki; Nagaya, Tadanobu; Shigeno, Takashi; Nakamura, Naoshi; Komatsu, Michiharu; Umemura, Takeji; Arakura, Norikazu; Matsumoto, Akihiro; Tanaka, Eiji;
DIGESTIVE DISEASES AND SCIENCES, 57(6), 1652-1659, 2012年06月

Hepatic Cerebroside Sulfotransferase is Induced by PPAR alpha Activation in Mice
Kimura, Takefumi; Nakajima, Takero; Tanaka, Naoki; Komatsu, Michiharu; Kamijo, Yuji; Tanaka, Eiji; Aoyama, Toshifumi;
GASTROENTEROLOGY, 142(5), S988-S988, 2012年05月

Association of IL28B gene polymorphism with development of hepatocellular carcinoma in Japanese patients with chronic hepatitis C virus infection
Joshita, Satoru; Umemura, Takeji; Katsuyama, Yoshihiko; Ichikawa, Yuki; Kimura, Takefumi; Morita, Susumu; Kamijo, Atsushi; Komatsu, Michiharu; Ichijo, Tetsuya; Matsumoto, Akihiro; Yoshizawa, Kaname; Kamijo, Nozomi; Ota, Masao; Tanaka, Eiji;
HUMAN IMMUNOLOGY, 73(3), 298-300, 2012年03月

Fatty Acid Accumulation and Resulting PPAR alpha Activation in Fibroblasts due to Trifunctional Protein Deficiency
Wakabayashi, Masato; Kamijo, Yuji; Nakajima, Takero; Tanaka, Naoki; Sugiyama, Eiko; Tian Yangyang; Kimura, Takefumi; Aoyama, Toshifumi;
PPAR RESEARCH, 2012, 371691, 2012年

Hepatic Cerebroside Sulfotransferase is Induced by PPAR alpha Activation in Mice
Kimura, Takefumi; Nakajima, Takero; Kamijo, Yuji; Tanaka, Naoki; Wang, Lixuan; Hara, Atsushi; Sugiyama, Eiko; Tanaka, Eiji; Gonzalez, Frank J.; Aoyama, Toshifumi;
PPAR RESEARCH, 2012, 174932, 2012年

ASSOCIATION ANALYSIS OF SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION 4 GENE POLYMORPHISMS WITH PRIMARY BILIARY CIRRHOSIS IN JAPANESE PATIENTS
Joshita, Satoru; Umemura, Takeji; Yoshizawa, Kaname; Katsuyama, Yoshihiko; Okuhara, Sadahisa; Ichikawa, Yuki; Kimura, Takefumi; Morita, Susumu; Komatsu, Michiharu; Ichijo, Tetsuya; Matsumoto, Akihiro; Ota, Masao; Tanaka, Eiji;
Hepatology, 54, 1203A-1203A, 2011年10月

Early detection of interstitial pneumonia by monitoring KL-6 in a chronic hepatitis C patient undergoing pegylated interferon and ribavirin therapy
Ichikawa-Yamada, Yuki; Joshita, Satoru; Tsukahara, Yoshinori; Kimura, Takefumi; Morita, Susumu; Kamijo, Atsushi; Umemura, Takeji; Ichijo, Tetsuya; Matsumoto, Akihiro; Yoshizawa, Kaname; Tanaka, Eiji;
HEPATOLOGY RESEARCH, 41(9), 904-909, 2011年09月

Enhanced Expression of Toll-Like Receptor 4 and MyD88 is Associated With Disease Progression in Human Nonalcoholic Fatty Liver Disease
Nagaya, Tadanobu; Tanaka, Naoki; Kimura, Takefumi; Komatsu, Michiharu; Tanaka, Eiji;
GASTROENTEROLOGY, 140(5), S978-S978, 2011年05月

A Case of Pyogenic Liver Abscess Infected with Fusobacterium necrophorum Depicted by Microscopy and Confirmed by Tissue Culture
Nozawa, Yuichi; Joshita, Satoru; Fukushima, Mana; Sugiyama, Yukiko; Ichikawa, Yuki; Kimura, Takefumi; Morita, Susumu; Kamijo, Atsushi; Umemura, Takeji; Ichijo, Tetsuya; Matsumoto, Akihiro; Yoshizawa, Kaname; Tanaka, Eiji;
INTERNAL MEDICINE, 50(17), 1815-1819, 2011年