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村田 敏規  ムラタ トシノリ

教員組織学術研究院(医学系)電話番号
教育組織医学部 医学科 眼科学FAX番号
職名教授メールアドレス
住所〒390-8621 長野県松本市旭3-1-1 信州大学眼科ホームページURL

更新日:2022/09/05

プロフィール

研究分野
糖尿病網膜症
キーワード:網膜 , 糖尿病網膜症
現在の研究課題
糖尿病網膜症の抗VEGF薬による治療

学歴
取得学位
医学博士 , 九州大学

免許・資格等
1986 , 医師免許
研究職歴等
研究職歴
1998-1999 , Harvard Medical School
1996-1998 , Doheny Eye Institute

研究活動業績

研究業績(著書・
発表論文等)
書籍等出版物
眼科局所治療薬データブック
メジカルビュー社 2015
Author:吉冨健志, 島崎潤, 村田敏規編集


眼科診療と関連法規
中山書店 2015
Author:鳥山佑一, 村田敏規編集


Myopic Macular Degeneration, Retina Fifth Edition , 1256-1266
Elsevier 2013
Author:Ohono-Matsui K, Ikuno Y, Yasuda M, Murata T, Sakamoto T, Ishibashi T


母斑症:von Hippel-Lindau病、網膜脳血管腫症, 眼科疾患 最新の治療2013-2015 , 224
2013
Author:村田 敏規


網膜症 黄斑症の治療/光凝固, 専門医のための眼科診療クオリファイ16 糖尿病眼合併症の新展開 , 111-118
2013
Author:村田 敏規


メディカルオフサルモロジー眼薬物治療のすべて
中山書店 2012
Author:村田敏規編


全身疾患と眼
中山書店 2011
Author:村田敏規編集


6.糖尿病 網膜症, 専門医のための眼科診療クオリファイ5 全身疾患と眼 , 89-97
2011
Author:村田 敏規


I 構造とその病態, 眼科学 , 407-410
2011
Author:村田敏規、今井弘毅、黒川徹


眼科疾患アプローチのための解剖生理, 薬局62(4) 増刊号 病気と薬 パーフェクトBOOK 62 , 1270-1273
2011
Author:村田 敏規


網膜色素上皮の構造, 大鹿哲郎編:眼科プラクティス 6眼科臨床に必要な解剖生理 , pp 226-231
文光堂,東京 2005
Author:向野利一郎,村田敏規


巻頭言, 編:日本眼科学会雑誌109号 , pp 557-558
2005
Author:村田敏規


論文
Treatment of diabetic macular edema in real-world clinical practice: The effect of aging
Journal of Diabetes Investigation,13(8):1339-1346 2022(Aug.)
Author:Kusuhara, Sentaro;Shimura, Masahiko;Kitano, Shigehiko;Sugimoto, Masahiko;Muramatsu, Daisuke;Fukushima, Harumi;Takamura, Yoshihiro;Matsumoto, Makiko;Kokado, Masahide;Kogo, Jiro;Sasaki, Mariko;Morizane, Yuki;Utsumi, Takuya;Kotake, Osamu;Koto, Takashi;Terasaki, Hiroto;Hirano, Takao;Ishikawa, Hiroto;Mitamura, Yoshinori;Okamoto, Fumiki;Kinoshita, Takamasa;Kimura, Kazuhiro;Yamashiro, Kenji;Suzuki, Yukihiko;Hikichi, Taiichi;Washio, Noriaki;Sato, Tomohito;Ohkoshi, Kishiko;Tsujinaka, Hiroki;Kondo, Mineo;Takagi, Hitoshi;Murata, Toshinori;Sakamoto, Taiji;Japan Clinical Retina Study (J-CREST) group
Abstract:Aims/Introduction In older patients, the management of diabetic macular edema (DME) can be complicated by comorbidities, geriatric syndrome, and socioeconomic status. This study aims to evaluate the effects of aging on the management of DME. Materials and Methods This is a real-world clinical study including 1,552 patients with treatment-naïve center-involved DME. The patients were categorized into 4 categories by age at baseline (C1, <55; C2, 55–64; C3, 65–74; and C4, ≥75 years). The outcomes were the change in logarithm of the minimum angle of resolution best-corrected visual acuity (logMAR BCVA) and central retinal thickness (CRT), and the number of treatments from baseline to 2 years. Results From baseline to 2 years, the mean changes in logMAR BCVA from baseline to 2 years were −0.01 in C1, −0.06 in C2, −0.07 in C3, and 0.01 in C4 (P = 0.016), and the mean changes in CRT were −136.2 μm in C1, −108.8 μm in C2, −100.6 μm in C3, and −89.5 μm in C4 (P = 0.008). Treatments applied in the 2 year period exhibited decreasing trends with increasing age category on the number of intravitreal injections of anti-VEGF agents (P = 0.06), selecting local corticosteroid injection (P = 0.031), vitrectomy (P < 0.001), and laser photocoagulation outside the great vascular arcade (P < 0.001). Conclusions Compared with younger patients with DME, patients with DME aged ≥75 years showed less frequent treatment, a lower BCVA gain, and a smaller CRT decrease. The management and visual outcome in older patients with DME would be unsatisfactory in real-world clinical practice.


Treatment of diabetic macular edema in real-world clinical practice: The effect of aging
JOURNAL OF DIABETES INVESTIGATION,13(8):1339-1346 2022(Aug.)
Author:Kusuhara, Sentaro; Shimura, Masahiko; Kitano, Shigehiko; Sugimoto, Masahiko; Muramatsu, Daisuke; Fukushima, Harumi; Takamura, Yoshihiro; Matsumoto, Makiko; Kokado, Masahide; Kogo, Jiro; Sasaki, Mariko; Morizane, Yuki; Utsumi, Takuya; Kotake, Osamu; Koto, Takashi; Terasaki, Hiroto; Hirano, Takao; Ishikawa, Hiroto; Mitamura, Yoshinori; Okamoto, Fumiki; Kinoshita, Takamasa; Kimura, Kazuhiro; Yamashiro, Kenji; Suzuki, Yukihiko; Hikichi, Taiichi; Washio, Noriaki; Sato, Tomohito; Ohkoshi, Kishiko; Tsujinaka, Hiroki; Kondo, Mineo; Takagi, Hitoshi; Murata, Toshinori; Sakamoto, Taiji; Japan Clinical Retina Study J-CRES;
Keywords:Aging; Diabetes; Diabetic macular edema;


Trends in the Prevalence and Progression of Diabetic Retinopathy Associated with Hyperglycemic Disorders during Pregnancy in Japan (vol 11, 165, 2022)
JOURNAL OF CLINICAL MEDICINE,11(10):2789 2022(May)
Author:Sugimoto, Masahiko; Sampa, Kohei; Tsukitome, Hideyuki; Kato, Kumiko; Matsubara, Hisashi; Asami, Shin; Sekimoto, Kaori; Kitano, Shigehiko; Yoshida, Shigeo; Takamura, Yoshihiro; Hirano, Takao; Murata, Toshinori; Shimizu, Miho; Kinoshita, Takamasa; Kusuhara, Sentaro; Sawada, Osamu; Ohji, Masahito; Yoshikawa, Rina; Kimura, Kazuhiro; Ishikawa, Hiroto; Gomi, Fumi; Terasaki, Hiroto; Kondo, Mineo; Ikeda, Tomoaki;


Relationship between central retinal sensitivity, thickness, perfusion density and visual acuity in patients with branch retinal vein occlusion
ACTA OPHTHALMOLOGICA,100(2):E610-E611 2022(Mar.)
Author:Hirabayashi, Kazutaka; Hoshiyama, Ken; Imai, Akira; Iesato, Yasuhiro; Hirano, Takao; Murata, Toshinori;


Comments on pupillometry: An objective test to assess endocular hereditary transthyretin amyloidosis
EUROPEAN JOURNAL OF OPHTHALMOLOGY,32(1):NP332-NP333 2022(Jan.)
Author:Kakihara, Shinji; Hirano, Takao; Imai, Akira; Miyahara, Teruyoshi; Murata, Toshinori;


OCULAR ANGIOGRAPHIC FEATURES IN JAPANESE PATIENTS WITH VAL30MET HEREDITARY TRANSTHYRETIN AMYLOIDOSIS
RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES,42(1):210-215 2022(Jan.)
Author:Kakihara, Shinji; Hirano, Takao; Kitahara, Junya; Matsuda, Yorishige; Imai, Akira; Miyahara, Teruyoshi; Murata, Toshinori;
Keywords:fluorescein angiography; hereditary transthyretin amyloidosis; indocyanine green angiography; ocular amyloid angiopathy; systemic severity;


Trends in the Prevalence and Progression of Diabetic Retinopathy Associated with Hyperglycemic Disorders during Pregnancy in Japan
JOURNAL OF CLINICAL MEDICINE,11(1):165 2022(Jan.)
Author:Sugimoto, Masahiko; Sampa, Kohei; Tsukitome, Hideyuki; Kato, Kumiko; Matsubara, Hisashi; Asami, Shin; Sekimoto, Kaori; Kitano, Shigehiko; Yoshida, Shigeo; Takamura, Yoshihiro; Hirano, Takao; Murata, Toshinori; Shimizu, Miho; Kinoshita, Takamasa; Kusuhara, Sentaro; Sawada, Osamu; Ohji, Masahito; Yoshikawa, Rina; Kimura, Kazuhiro; Ishikawa, Hiroto; Gomi, Fumi; Terasaki, Hiroto; Kondo, Mineo; Ikeda, Tomoaki; Writing Comm Japan Clinical Retina;
Keywords:gestational diabetes mellitus; hyperglycemic disorders during pregnancy; overt diabetes mellitus; pre-existing diabetes mellitus;


Estimating ranibizumab injection numbers and visual acuity at 12 months based on 2-month data on branch retinal vein occlusion treatment
SCIENTIFIC REPORTS,12(1):7661 2022
Author:Murata, Toshinori; Kondo, Mineo; Inoue, Makoto; Nakao, Shintaro; Osaka, Rie; Shiragami, Chieko; Sogawa, Kenji; Mochizuki, Akikazu; Shiraga, Rumiko; Kaneko, Takeumi; Chandrasekhar, Chikatapu; Tsujikawa, Akitaka; Kamei, Motohiro;


Widefield Optical Coherence Tomography Angiography for Pregnancy-Associated Central Serous Chorioretinopathy
ASIA-PACIFIC JOURNAL OF OPHTHALMOLOGY,11(3):294-294 2022
Author:Kakihara, Shinji; Hirano, Takao; Wakabayashi, Masumi; Murata, Toshinori;


Estimating ranibizumab injection numbers and visual acuity at 12 months based on 2-month data on branch retinal vein occlusion treatment
SCIENTIFIC REPORTS,12(1):7661 2022
Author:Murata, Toshinori; Kondo, Mineo; Inoue, Makoto; Nakao, Shintaro; Osaka, Rie; Shiragami, Chieko; Sogawa, Kenji; Mochizuki, Akikazu; Shiraga, Rumiko; Kaneko, Takeumi; Chandrasekhar, Chikatapu; Tsujikawa, Akitaka; Kamei, Motohiro;


Background Factors Affecting Visual Acuity at Initial Visit in Eyes with Central Retinal Vein Occlusion: Multicenter Study in Japan
JOURNAL OF CLINICAL MEDICINE,10(23):5619 2021(Dec.)
Author:Kondo, Mineo; Noma, Hidetaka; Shimura, Masahiko; Sugimoto, Masahiko; Matsui, Yoshitsugu; Kato, Kumiko; Saishin, Yoshitsugu; Ohji, Masahito; Ishikawa, Hiroto; Gomi, Fumi; Iwata, Kensaku; Yoshida, Shigeo; Kusuhara, Sentaro; Hirai, Hiromasa; Ogata, Nahoko; Hirano, Takao; Murata, Toshinori; Tsuboi, Kotaro; Kamei, Motohiro; Kinoshita, Takamasa; Kuwayama, Soichiro; Hirano, Yoshio; Ohta, Manami; Kimura, Kazuhiro; Takayama, Kei; Takeuchi, Masaru; Takamura, Yoshihiro; Okamoto, Fumiki; Mitamura, Yoshinori; Terasaki, Hiroto; Sakamoto, Taiji; Japan Clinical Retina Study J-CR;
Keywords:central retinal vein occlusion; visual acuity; multicenter study;


Background Factors Affecting Visual Acuity at Initial Visit in Eyes with Central Retinal Vein Occlusion : Multicenter Study in Japan
Journal of Clinical Medicine,10(23):5619 2021(Nov. 29)
Author:Kondo, Mineo;Noma, Hidetaka;Shimura, Masahiko;Sugimoto, Masahiko;Matsui, Yoshitsugu;Kato, Kumiko;Saishin, Yoshitsugu;Ohji, Masahito;Ishikawa, Hiroto;Gomi, Fumi;Iwata, Kensaku;Yoshida, Shigeo;Kusuhara, Sentaro;Hirai, Hiromasa;Ogata, Nahoko;Hirano, Takao;Murata, Toshinori;Tsuboi, Kotaro;Kamei, Motohiro;Kinoshita, Takamasa;Kuwayama, Soichiro;Hirano, Yoshio;Ohta, Manami;Kimura, Kazuhiro;Takayama, Kei;Takeuchi, Masaru;Takamura, Yoshihiro;Okamoto, Fumiki;Mitamura, Yoshinori;Terasaki, Hiroto;Sakamoto, Taiji
Abstract:Purpose: To determine the baseline characteristics of patients with central retinal vein occlusion (CRVO) that were significantly associated with the best-corrected visual acuity (BCVA) at the initial examination. Methods: This was a retrospective multicenter study using the medical records registered in 17 ophthalmological institutions in Japan. Patients with untreated CRVO (≥20-years-of-age) who were initially examined between January 2013 and December 2017 were studied. The patients’ baseline factors that were significantly associated with the BCVA at the initial examination were determined by univariate and multivariate linear regression analyses. Results: Data from 517 eyes of 517 patients were analyzed. Univariate analyses showed that an older age (r = 0.194, p < 0.001) and the right eye (r = −0.103, p < 0.019) were significantly associated with poorer BCVA at the initial visit. Multivariate analyses also showed that an older age (β = 0.191, p < 0.001) and the right eye (β = −0.089, p = 0.041) were significantly associated with poorer BCVA at the initial visit. Conclusions: The results indicate that an older age, a known strong factor, and the right eye were significantly associated with poorer BCVA at the initial visit to the hospital. These results suggest that functional and/or anatomical differences between the right and left eyes may be involved in these results.


Evaluation of the vitreoretinal interface in eyes with diabetic retinopathy using a 23 mm wide-field OCT
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE,62(8) 2021(Jun.)
Author:Hirano, Takao; Chiku, Yoshiaki; Hoshiyama, Ken; Murata, Toshinori;


Pathophysiological roles of adrenomedullin-2 in mouse model of ocular neovascularization
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE,62(8) 2021(Jun.)
Author:Kakihara, Shinji; Tanaka, Masaaki; Hirabayashi, Kazutaka; Imai, Akira; Toriyama, Yuichi; Iesato, Yasuhiro; Sakurai, Takayuki; Kamiyoshi, Akiko; Kawate, Hisaka; Ichikawa-Shindo, Yuka; Tanaka, Megumu; Murata, Toshinori; Shindo, Takayuki;


Changes in retinal sensitivity, thickness, and perfusion density following treatment for branch retinal vein occlusion (BRVO)
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE,62(8) 2021(Jun.)
Author:Hirabayashi, Kazutaka; Sadda, Srinivas R.; Imai, Akira; Iesato, Yasuhiro; Murata, Toshinori;


Treat-and-extend therapy with aflibercept for diabetic macular edema: a prospective clinical trial
JAPANESE JOURNAL OF OPHTHALMOLOGY,65(3):354-362 2021(May)
Author:Hirano, Takao; Toriyama, Yuichi; Takamura, Yoshihiro; Sugimoto, Masahiko; Nagaoka, Taiji; Sugiura, Yoshimi; Okamoto, Fumiki; Saito, Michiyuki; Noda, Kousuke; Yoshida, Shigeo; Ishibazawa, Akihiro; Sawada, Osamu; Murata, Toshinori;
Keywords:Aflibercept; Diabetic macular edema; Focal; grid photocoagulation; Treat-and-extend;


Ten-year changes in visual acuity at baseline and at 2 years after treatment in a Japanese population with age-related macular degeneration
GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY,259(5):1191-1198 2021(May)
Author:Sawada, Tomoko; Yasukawa, Tsutomu; Imaizumi, Hiroko; Matsubara, Hisashi; Kimura, Kazuhiro; Terasaki, Hiroto; Ishikawa, Hiroto; Murakami, Tomoya; Takeuchi, Masaru; Mitamura, Yoshinori; Yamashita, Mariko; Takamura, Yoshihiro; Murata, Toshinori; Kogo, Jiro; Ohji, Masahito; J-CREST Japan Clin Retinal Study;
Keywords:Age-related macular degeneration; Baseline visual acuity; Anti-vascular endothelial growth factor; Photodynamic therapy; J-CREST Study group;


Adrenomedullin–Receptor Activity-Modifying Protein 2 System Ameliorates Subretinal Fibrosis by Suppressing Epithelial-Mesenchymal Transition in Age-Related Macular Degeneration
The American Journal of Pathology,191(4):652-668 2021(Apr.)
Author:Masaaki Tanaka;Shinji Kakihara;Kazutaka Hirabayashi;Akira Imai;Yuichi Toriyama;Yasuhiro Iesato;Takayuki Sakurai;Akiko Kamiyoshi;Yuka Ichikawa-Shindo;Hisaka Kawate;Megumu Tanaka;Nanqi Cui;Yangxuan Wei;Yunlu Zhao;Kohsuke Aruga;Akihiro Yamauchi;Toshinori Murata;Takayuki Shindo


Adrenomedullin-Receptor Activity-Modifying Protein 2 System Ameliorates Subretinal Fibrosis by Suppressing Epithelial-Mesenchymal Transition in Age-Related Macular Degeneration
AMERICAN JOURNAL OF PATHOLOGY,191(4):652-668 2021(Apr.)
Author:Tanaka, Masaaki; Kakihara, Shinji; Hirabayashi, Kazutaka; Imai, Akira; Toriyama, Yuichi; Iesato, Yasuhiro; Sakurai, Takayuki; Kamiyoshi, Akiko; Ichikawa-Shindo, Yuka; Kawate, Hisaka; Tanaka, Megumu; Cui, Nanqi; Wei, Yangxuan; Zhao, Yunlu; Aruga, Kohsuke; Yamauchi, Akihiro; Murata, Toshinori; Shindo, Takayuki;


Relationship between central retinal sensitivity, thickness, perfusion density and visual acuity in patients with branch retinal vein occlusion
Acta Ophthalmol 2021(Mar.)
Author:Hirabayashi K, Hoshiyama K, Imai A, Iesato Y, Hirano T, Murata T.


Micropulse laser trabeculoplasty under maximal tolerable glaucoma eyedrops: treatment effectiveness and impact of surgical expertise
Int J Ophthalmol,14(3):388-392 2021(Mar.)
Author:Kakihara S, Hirano T, Imai A, Kurenuma T, Chiku Y, Murata T.


Outcomes of a 2-year treat-and-extend regimen with aflibercept for diabetic macular edema
Sci Rep,11(1):4488 2021(Feb.)
Author:Hirano T, Toriyama Y, Takamura Y, Sugimoto M, Nagaoka T, Sugiura Y, Okamoto F, Saito M, Noda K, Yoshida S, Ishibazawa A, Sawada O, Murata T.


The randomized ZIPANGU trial of ranibizumab and adjunct laser for macular edema following branch retinal vein occlusion in treatment-naïve patients
Scientific Reports,11(1) 2021(Jan. 12)
Author:Toshinori Murata;Mineo Kondo;Makoto Inoue;Shintaro Nakao;Rie Osaka;Chieko Shiragami;Kenji Sogawa;Akikazu Mochizuki;Rumiko Shiraga;Yohei Ohashi;Takeumi Kaneko;Chikatapu Chandrasekhar;Akitaka Tsujikawa;Motohiro Kamei
Abstract:AbstractThe ZIPANGU study assessed the efficacy and safety of ranibizumab as a one loading dose + pro re nata (one + PRN) regimen with/without focal/grid laser among treatment-naïve patients suffering from macular edema (ME) following branch retinal vein occlusion (BRVO). ZIPANGU was a phase IV, prospective, randomized, open-label, active-controlled, 12-month, two-arm, multicenter study. Treatment-naïve patients with visual impairment (19–73 letters) caused by ME, defined as central subfield thickness (CSFT) > 300 µm, due to BRVO were randomly assigned to ranibizumab monotherapy (n = 29) or combination therapy (ranibizumab + focal/grid short-pulse laser, n = 30). The primary endpoint was the number of ranibizumab injections. Secondary endpoints were mean changes in best-corrected visual acuity (BCVA) and CSFT, and safety. There were no statistically significant differences in the mean number of ranibizumab injections between monotherapy (4.3 injections) vs. combination (4.1 injections) therapy, or in CSFT. BCVA improvement in the monotherapy arm (22.0 letters) was better than the combination therapy arm (15.0 letters) (p = 0.035). Overall, both regimens appeared to be safe and well tolerated. One + PRN ranibizumab is safe and efficacious in treatment-naïve patients with ME secondary to BRVO. A conjunctive laser treatment did not lead to better functional outcomes or fewer ranibizumab injections.


Deposits on Retinal Surface Seen on OCT in Ocular Amyloidosis
Ophthalmol Retina,:S2468-6530(20)30514-5 2021(Jan.)
Author:Kakihara S, Hirano T, Matsuda Y, Takano D, Imai A, Miyahara T, Murata T.


The randomized ZIPANGU trial of ranibizumab and adjunct laser for macular edema following branch retinal vein occlusion in treatment-naïve patients
Sci Rep,11(1):551 2021(Jan.)
Author:Murata T, Kondo M, Inoue M, Nakao S, Osaka R, Shiragami C, Sogawa K, Mochizuki A, Shiraga R, Ohashi Y, Kaneko T, Chandrasekhar C, Tsujikawa A, Kamei M.


Treat-and-extend therapy with aflibercept for diabetic macular edema : a prospective clinical trial
Japanese journal of ophthalmology : the official international journal of the Japanese Ophthalmological Society / Japanese Ophthalmological Society,65(3):354-362 2021
Author:Takao Hirano;Yuichi Toriyama;Yoshihiro Takamura;Masahiko Sugimoto;Taiji Nagaoka;Yoshimi Sugiura;Fumiki Okamoto;Michiyuki Saito;Kousuke Noda;Shigeo Yoshida;Akihiro Ishibazawa;Osamu Sawada;Toshinori Murata


The randomized ZIPANGU trial of ranibizumab and adjunct laser for macular edema following branch retinal vein occlusion in treatment-naive patients
SCIENTIFIC REPORTS,11(1):551 2021
Author:Murata, Toshinori; Kondo, Mineo; Inoue, Makoto; Nakao, Shintaro; Osaka, Rie; Shiragami, Chieko; Sogawa, Kenji; Mochizuki, Akikazu; Shiraga, Rumiko; Ohashi, Yohei; Kaneko, Takeumi; Chandrasekhar, Chikatapu; Tsujikawa, Akitaka; Kamei, Motohiro;


Outcomes of a 2-year treat-and-extend regimen with aflibercept for diabetic macular edema
SCIENTIFIC REPORTS,11(1):4488 2021
Author:Hirano, Takao; Toriyama, Yuichi; Takamura, Yoshihiro; Sugimoto, Masahiko; Nagaoka, Taiji; Sugiura, Yoshimi; Okamoto, Fumiki; Saito, Michiyuki; Noda, Kousuke; Yoshida, Shigeo; Ishibazawa, Akihiro; Sawada, Osamu; Murata, Toshinori;


Micropulse laser trabeculoplasty under maximal tolerable glaucoma eyedrops: treatment effectiveness and impact of surgical expertise
INTERNATIONAL JOURNAL OF OPHTHALMOLOGY,14(3):388-392 2021
Author:Kakihara, Shinji; Hirano, Takao; Imai, Akira; Kurenuma, Taihei; Chiku, Yoshiaki; Murata, Toshinori;
Keywords:micropulse laser trabeculoplasty; open angle glaucoma; inter-operator variability;


The randomized ZIPANGU trial of ranibizumab and adjunct laser for macular edema following branch retinal vein occlusion in treatment-naive patients (vol 11, 551, 2021)
SCIENTIFIC REPORTS,11(1):14400 2021
Author:Murata, Toshinori; Kondo, Mineo; Inoue, Makoto; Nakao, Shintaro; Osaka, Rie; Shiragami, Chieko; Sogawa, Kenji; Mochizuki, Akikazu; Shiraga, Rumiko; Ohashi, Yohei; Kaneko, Takeumi; Chandrasekhar, Chikatapu; Tsujikawa, Akitaka; Kamei, Motohiro;


Evaluating posterior vitreous detachment by widefield 23-mm swept-source optical coherence tomography imaging in healthy subjects
SCIENTIFIC REPORTS,11(1):19754 2021
Author:Chiku, Yoshiaki; Hirano, Takao; Takahashi, Yoshiaki; Tuchiya, Ayako; Nakamura, Marie; Murata, Toshinori;


Real-world management of treatment-naïve diabetic macular oedema: 2-year visual outcome focusing on the starting year of intervention from STREAT-DMO study
Br J Ophthalmol,104(12):1755-1761 2020(Dec.)
Author:Shimura M, Kitano S, Muramatsu D, Fukushima H, Takamura Y, Matsumoto M, Kokado M, Kogo J, Sasaki M, Morizane Y, Utsumi T, Koto T, Sonoda S, Hirano T, Ishikawa H, Mitamura Y, Okamoto F, Kinoshita T, Kimura K, Sugimoto M, Yamashiro K, Suzuki Y, Hikichi T, Washio N, Sato T, Ohkoshi K, Tsujinaka H, Kusuhara S, Kondo M, Takagi H, Murata T, Sakamoto T; Japan Clinical Retina Study (J-CREST) group.


Real-world management of treatment-naive diabetic macular oedema: 2-year visual outcome focusing on the starting year of intervention from STREAT-DMO study
BRITISH JOURNAL OF OPHTHALMOLOGY,104(12):1755-1761 2020(Dec.)
Author:Shimura, Masahiko; Kitano, Shigehiko; Muramatsu, Daisuke; Fukushima, Harumi; Takamura, Yoshihiro; Matsumoto, Makiko; Kokado, Masahide; Kogo, Jiro; Sasaki, Mariko; Morizane, Yuki; Utsumi, Takuya; Koto, Takashi; Sonoda, Shozo; Hirano, Takao; Ishikawa, Hiroto; Mitamura, Yoshinori; Okamoto, Fumiki; Kinoshita, Takamasa; Kimura, Kazuhiro; Sugimoto, Masahiko; Yamashiro, Kenji; Suzuki, Yukihiko; Hikichi, Taiichi; Washio, Noriaki; Sato, Tomohito; Ohkoshi, Kishiko; Tsujinaka, Hiroki; Kusuhara, Sentaro; Kondo, Mineo; Takagi, Hitoshi; Murata, Toshinori; Sakamoto, Taiji; Japan Clinical Retina Study J-CRES;
Keywords:epidemiology; macula; retina;


Real-world management of treatment-naive diabetic macular oedema: 2-year visual outcome focusing on the starting year of intervention from STREAT-DMO study
BRITISH JOURNAL OF OPHTHALMOLOGY,104(12):1755-1761 2020(Dec.)
Author:Shimura, Masahiko; Kitano, Shigehiko; Muramatsu, Daisuke; Fukushima, Harumi; Takamura, Yoshihiro; Matsumoto, Makiko; Kokado, Masahide; Kogo, Jiro; Sasaki, Mariko; Morizane, Yuki; Utsumi, Takuya; Koto, Takashi; Sonoda, Shozo; Hirano, Takao; Ishikawa, Hiroto; Mitamura, Yoshinori; Okamoto, Fumiki; Kinoshita, Takamasa; Kimura, Kazuhiro; Sugimoto, Masahiko; Yamashiro, Kenji; Suzuki, Yukihiko; Hikichi, Taiichi; Washio, Noriaki; Sato, Tomohito; Ohkoshi, Kishiko; Tsujinaka, Hiroki; Kusuhara, Sentaro; Kondo, Mineo; Takagi, Hitoshi; Murata, Toshinori; Sakamoto, Taiji; Japan Clinical Retina Study J-CRES;
Keywords:epidemiology; macula; retina;


Real-world management of treatment-naïve diabetic macular oedema in Japan: two-year visual outcomes with and without anti-VEGF therapy in the STREAT-DME study
Br J Ophthalmol,104(9):1209-1215 2020(Sep.)
Author:Shimura M, Kitano S, Muramatsu D, Fukushima H, Takamura Y, Matsumoto M, Kokado M, Kogo J, Sasaki M, Morizane Y, Kotake O, Koto T, Sonoda S, Hirano T, Ishikawa H, Mitamura Y, Okamoto F, Kinoshita T, Kimura K, Sugimoto M, Yamashiro K, Suzuki Y, Hikichi T, Washio N, Sato T, Ohkoshi K, Tsujinaka H, Kusuhara S, Kondo M, Takagi H, Murata T, Sakamoto T; Japan Clinical Retina Study (J-CREST) group.


Baerveldt glaucoma drainage implant surgery for secondary glaucoma in patients with transthyretin-related familial amyloid polyneuropathy
Jpn J Ophthalmol,64(5):533-538 2020(Sep.)
Author:Kakihara S, Hirano T, Imai A, Miyahara T, Murata T.


Baerveldt glaucoma drainage implant surgery for secondary glaucoma in patients with transthyretin-related familial amyloid polyneuropathy
JAPANESE JOURNAL OF OPHTHALMOLOGY,64(5):533-538 2020(Sep.)
Author:Kakihara, Shinji; Hirano, Takao; Imai, Akira; Miyahara, Teruyoshi; Murata, Toshinori;
Keywords:Baerveldt glaucoma drainage implant; Familial amyloid polyneuropathy; Secondary glaucoma; Transthyretin; Tube implant;


Real-world management of treatment-naive diabetic macular oedema in Japan: two-year visual outcomes with and without anti-VEGF therapy in the STREAT-DME study
BRITISH JOURNAL OF OPHTHALMOLOGY,104(9):1209-1215 2020(Sep.)
Author:Shimura, Masahiko; Kitano, Shigehiko; Muramatsu, Daisuke; Fukushima, Harumi; Takamura, Yoshihiro; Matsumoto, Makiko; Kokado, Masahide; Kogo, Jiro; Sasaki, Mariko; Morizane, Yuki; Kotake, Osamu; Koto, Takashi; Sonoda, Shozo; Hirano, Takao; Ishikawa, Hiroto; Mitamura, Yoshinori; Okamoto, Fumiki; Kinoshita, Takamasa; Kimura, Kazuhiro; Sugimoto, Masahiko; Yamashiro, Kenji; Suzuki, Yukihiko; Hikichi, Taiichi; Washio, Noriaki; Sato, Tomohito; Ohkoshi, Kishiko; Tsujinaka, Hiroki; Kusuhara, Sentaro; Kondo, Mineo; Takagi, Hitoshi; Murata, Toshinori; Sakamoto, Taiji; Japan Clinical Retina Study J-CRES;


Vitreoretinal Interface Slab in OCT Angiography for Detecting Diabetic Retinal Neovascularization
Ophthalmol Retina,4(6):588-594 2020(Jun.)
Author:Hirano T, Hoshiyama K, Hirabayashi K, Wakabayashi M, Toriyama Y, Tokimitsu M, Murata T.


Prediction of post-treatment retinal sensitivity by baseline retinal perfusion density measurements in eyes with branch retinal vein occlusion
Sci Rep,10(1):9614 2020(Jun.)
Author:Rachima S, Hirabayashi K, Imai A, Iesato Y, Murata T.


The therapeutic potency of exogenous administration of adrenomedullin-2 in ocular neovascular diseases
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE,61(7) 2020(Jun.)
Author:Kakihara, Shinji; Tanaka, Masaaki; Hirabayashi, Kazutaka; Imai, Akira; Toriyama, Yuichi; Iesato, Yasuhiro; Sakurai, Takayuki; Kamiyoshi, Akiko; Kawate, Hisaka; Ichikawa-Shindo, Yuka; Tanaka, Megumu; Dai, Kun; Cui, Nanqi; Wei, Yangxuan; Murata, Toshinori; Shindo, Takayuki;


Evaluation of wide-field OCT angiography using Xephilio OCT-S1 for detecting retinal neovascularization in eyes with proliferative diabetic retinopathy
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE,61(7) 2020(Jun.)
Author:Hirano, Takao; Hoshiyama, Ken; Toriyama, Yuichi; Murata, Toshinori;


Comparison of ranibizumab with or without focal/grid laser for macular edema secondary to branch retinal vein occlusion: 12-month results from the ZIPANGU study
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE,61(7) 2020(Jun.)
Author:Murata, Toshinori; Kondo, Mineo; Inoue, Makoto; Nakao, Shintaro; Osaka, Rie; Shiragami, Chieko; Sogawa, Kenji; Mochizuki, Akikazu; Shiraga, Rumiko; Ohashi, Yohei; Kaneko, Takeumi; Tsujikawa, Akitaka; Kamei, Motohiro;


Investigation of the therapeutic mechanism of subthreshold micropulse laser irradiation in retina
Graefes Arch Clin Exp Ophthalmol,258(5):1039-1047 2020(May)
Author:Hirabayashi K, Kakihara S, Tanaka M, Shindo T, Murata T.


Investigation of the therapeutic mechanism of subthreshold micropulse laser irradiation in retina
GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY,258(5):1039-1047 2020(May)
Author:Hirabayashi, Kazutaka; Kakihara, Shinji; Tanaka, Masaaki; Shindo, Takayuki; Murata, Toshinori;
Keywords:Subthreshold micropulse laser; Retinal edema; Aquaporin-3; Gene expression;


Small gauge vitrectomy for vitreous amyloidosis and subsequent management of secondary glaucoma in patients with hereditary transthyretin amyloidosis
SCIENTIFIC REPORTS,10(1):5574 2020
Author:Kakihara, Shinji; Hirano, Takao; Imai, Akira; Miyahara, Teruyoshi; Murata, Toshinori;


Prediction of post-treatment retinal sensitivity by baseline retinal perfusion density measurements in eyes with branch retinal vein occlusion
SCIENTIFIC REPORTS,10(1):9614 2020
Author:Rachima, Soraya; Hirabayashi, Kazutaka; Imai, Akira; Iesato, Yasuhiro; Murata, Toshinori;


Pathophysiological significance of adrenomedullin-RAMP2 system in age-related macular degeneration
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE,60(9) 2019(Jul.)
Author:Tanaka, Masaaki; Hirabayashi, Kazutaka; Imai, Akira; Toriyama, Yuichi; Iesato, Yasuhiro; Yamauchi, Akihiro; Tanaka, Megumu; Sakurai, Takayuki; Kamiyoshi, Akiko; Ichikawa-Shindo, Yuka; Kawate, Hisaka; Murata, Toshinori; Shindo, Takayuki;


One year follow-up data on changes in aqueous VEGF levels in eyes with diabetic macula edema treated with ranibizumab using the pro re nata regimen
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE,60(9) 2019(Jul.)
Author:Hirano, Takao; Toriyama, Yuichi; Hirabayashi, Kazutaka; Murata, Toshinori;


Correlation between initial visit binocular intraocular pressure difference and mean pulse pressure, and the number of ranibizumab administrations in branch retinal vein occlusion
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE,60(9) 2019(Jul.)
Author:Hirabayashi, Kazutaka; Imai, Akira; Iesato, Yasuhiro; Murata, Toshinori;


Change of baseline visual acuity in eyes with age-related macular degeneration from 2006-2015
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE,60(9) 2019(Jul.)
Author:Sawada, Tomoko; Yasukawa, Tsutomu; Imaizumi, Hiroko; Mastubara, Hisashi; Kimura, Kazuhiro; Terasaki, Hiroto; Ishikawa, Hiroto; Murakami, Tomoya; Takeuchi, Masaru; Mitamura, Yoshinori; Yamashita, Mariko; Takamura, Yoshihiro; Murata, Toshinori; Kogo, Jiro; Sakamoto, Taiji; Ohji, Masahito;


Change in 1-year visual acuity gain with age-related macular degeneration from 2006 and 2015
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE,60(9) 2019(Jul.)
Author:Nishino, Sachi; Yasukawa, Tsutomu; Imaizumi, Hiroko; Mastubara, Hisashi; Ishikawa, Hiroto; Kimura, Kazuhiro; Terasaki, Hiroto; Mitamura, Yoshinori; Murata, Toshinori; Yamashita, Mariko; Kogo, Jiro; Takeuchi, Masaru; Takamura, Yoshihiro; Murakami, Tomoya; Sakamoto, Taiji; Ohji, Masahito;


Quantifying vascular density and morphology using different swept-source optical coherence tomography angiographic scan patterns in diabetic retinopathy
BRITISH JOURNAL OF OPHTHALMOLOGY,103(2):216-221 2019(Feb.)
Author:Hirano, Takao; Kitahara, Jyunya; Toriyama, Yuichi; Kasamatsu, Hirotsugu; Murata, Toshinori; Sadda, Srinivas;
Keywords:Imaging; Retina;


Development of a Novel Model of Central Retinal Vascular Occlusion and the Therapeutic Potential of the Adrenomedullin-Receptor Activity-Modifying Protein 2 System
AMERICAN JOURNAL OF PATHOLOGY,189(2):449-466 2019(Feb.)
Author:Hirabayashi, Kazutaka; Tanaka, Masaaki; Imai, Akira; Toriyama, Yuichi; Iesato, Yasuhiro; Sakurai, Takayuki; Kamiyoshi, Akiko; Ichikawa-Shindo, Yuka; Kawate, Hisaka; Tanaka, Megumu; Dai, Kun; Cui, Nanqi; Wei, Yangxuan; Nakamura, Keisei; Iida, Shiho; Matsui, Shuhei; Yamauchi, Akihiro; Murata, Toshinori; Shindo, Takayuki;


Effect of Leaking Foveal Microaneurysms on the Treatment of Center-Involving Diabetic Macular Edema: A Pilot Study
OPHTHALMIC RESEARCH,61(1):10-18 2019
Author:Hirano, Takao; Toriyama, Yuichi; Iesato, Yasuhiro; Ishibazawa, Akihiro; Sugimoto, Masahiko; Takamura, Yoshihiro; Nagaoka, Taiji; Murata, Toshinori;
Keywords:Diabetic macular edema; Vascular endothelial growth factor; Focal; grid laser; Capillary nonperfusion; Short-pulse laser;


Wide-field en face swept-source optical coherence tomography angiography using extended field imaging in diabetic retinopathy
BRITISH JOURNAL OF OPHTHALMOLOGY,102(9):1199-1203 2018(Sep.)
Author:Hirano, Takao; Kakihara, Shinji; Toriyama, Yuichi; Nittala, Muneeswar Gupta; Murata, Toshinori; Sadda, Srinivas;


CHANGES IN PLASMA VASCULAR ENDOTHELIAL GROWTH FACTOR LEVEL AFTER INTRAVITREAL INJECTION OF BEVACIZUMAB, AFLIBERCEPT, OR RANIBIZUMAB FOR DIABETIC MACULAR EDEMA
RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES,38(9):1801-1808 2018(Sep.)
Author:Hirano, Takao; Toriyama, Yuichi; Iesato, Yasuhiro; Imai, Akira; Murata, Toshinori;
Keywords:aflibercept; anti-vascular endothelial growth factor agents; arterial thromboembolic events; bevacizumab; intravitreal injection; diabetic macular edema; diabetic retinopathy; plasma vascular endo-thelial growth factor level; ranibizumab; vascular endothelial growth factor;


Identifying suspicious regions in optical coherence tomography angiography using convolutional neural networks
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE,59(9) 2018(Jul.)
Author:Leahy, Conor; Perez, Thomas; Durbin, Mary K.; Kashani, Amir H.; Murata, Toshinori; Shemonski, Nathan;


Extended field imaging using swept-source optical coherence tomography angiography in retinal vein occlusion
JAPANESE JOURNAL OF OPHTHALMOLOGY,62(3):274-279 2018(May)
Author:Kakihara, Shinji; Hirano, Takao; Iesato, Yasuhiro; Imai, Akira; Toriyama, Yuichi; Murata, Toshinori;
Keywords:Retinal vein occlusion; Optical coherence tomography; Optical coherence tomography angiography; Capillary nonperfusion; Fluorescein angiography;


INTERNAL LIMITING MEMBRANE PEELING-DEPENDENT RETINAL STRUCTURAL CHANGES AFTER VITRECTOMY IN RHEGMATOGENOUS RETINAL DETACHMENT
RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES,38(3):471-479 2018(Mar.)
Author:Hisatomi, Toshio; Tachibana, Takashi; Notomi, Shoji; Koyanagi, Yoshito; Murakami, Yusuke; Takeda, Atsunobu; Ikeda, Yasuhiro; Yoshida, Shigeo; Enaida, Hiroshi; Murata, Toshinori; Sakamoto, Taiji; Sonoda, Koh-Hei; Ishibashi, Tatsuro;
Keywords:dissociated optic nerve fiber layer; epiretinal membrane; internal limiting membrane; Muller cell; posterior vitreous detachment; rhegmatogenous retinal detachment; 3-dimensional optical coherence tomography; vitrectomy; vitreous cortex; macular pucker;


Management of diabetic macular edema in Japan: a review and expert opinion
JAPANESE JOURNAL OF OPHTHALMOLOGY,62(1):1-23 2018(Jan.)
Author:Terasaki, Hiroko; Ogura, Yuichiro; Kitano, Shigehiko; Sakamoto, Taiji; Murata, Toshinori; Hirakata, Akito; Ishibashi, Tatsuro;
Keywords:Diabetic retinopathy; Diabetic macular edema; Vascular endothelial growth factor; Multidisciplinary treatment; Expert opinion;


New Strategies for Treatment of Diabetic Macular Edema
JOURNAL OF OPHTHALMOLOGY,2018:4292154 2018
Author:Takamura, Yoshihiro; Ohkoshi, Kishiko; Murata, Toshinori;


Complete regression of branching vascular network in polypoidal choroidal vasculopathy by ranibizumab and photodynamic therapy, two case reports
BMC OPHTHALMOLOGY,18:284 2018
Author:Iesato, Yasuhiro; Tanaka, Masaaki; Murata, Masako; Kitahara, Junya; Hirano, Takao; Kurenuma, Taihei; Yoshida, Noriko; Murata, Toshinori;
Keywords:Polypoidal choroidal vasculopathy; Branching vascular network; Polypoidal lesions; Ranibizumab; Photodynamic therapy; Optical coherence tomography angiography;


Assessment of diabetic retinopathy using two ultra-wide-field fundus imaging systems, the Clarus (R) and Optos systems
BMC OPHTHALMOLOGY,18:332 2018
Author:Hirano, Takao; Imai, Akira; Kasamatsu, Hirotsugu; Kakihara, Shinji; Toriyama, Yuichi; Murata, Toshinori;
Keywords:Diabetic mellitus; Diabetic retinopathy; Ultra-wide-field retinal imaging systems; Early treatment of diabetic retinopathy study diabetic retinopathy severity; International clinical diabetic retinopathy severity;


One-Year Outcomes following Intravitreal Aflibercept for Polypoidal Choroidal Vasculopathy in Japanese Patients: The APOLLO Study.
Ophthalmologica,238(3):163-171 2017
Author:Oshima Y, Kimoto K, Yoshida N, Fujisawa K, Sonoda S, Kubota T, Murata T, Sakamoto T, Yoshida S, Sonoda KH, Ishibashi T.


COMPLETE REPAIR OF RETINAL STRUCTURE AFTER VITRECTOMY WITH INTERNAL LIMITING MEMBRANE PEELING.
Retina,37(8):1523-1528 2017
Author:Hisatomi T, Tachibana T, Notomi S, Nakatake S, Fujiwara K, Murakami Y, Ikeda Y, Yoshida S, Enaida H, Murata T, Sakamoto T, Sonoda KH, Ishibashi T.


Effect of leaking perifoveal microaneurysms on resolution of diabetic macular edema treated by combination therapy using anti-vascular endothelial growth factor and short pulse focal/grid laser photocoagulation
Jpn J Ophthalmol,61(1):51-60 2017
Author:Hirano T, Toriyama Y, Iesato Y, Imai A, Hirabayashi K, Nagaoka T, Takamura Y, Sugimoto M, Murata T.


糖尿病網膜症 外科治療Update
プラクティス,33(5):559-566 2016
Author:平野 隆雄、村田 敏規


糖尿病黄斑浮腫におけるベバシズマブ反応不良例のラニビズマブへのスイッチ療法の検討
あたらしい眼科,33(2):295-299 2016
Author:平野 隆雄、鳥山 佑一、松田 順繁、時光 元温、京本 敏行、千葉 大、村田 敏規


Delineation of capillary dropout in the deep retinal capillary plexus using optical coherence tomography angiography in a patient with Purtscher's retinopathy exhibiting normal fluorescein angiography findings
,16(1):113 2016
Author:Motoharu Tokimitsu, Masako Murata, Yuuichi Toriyama, Takao Hirano, Yasuhiro Iesato, Toshinori Murata


Adrenomedullin: A potential therapeutic target for retinochoroidal disease
Progress in Retinal and Eye Research,52:112-129 2016
Author:Yasuhiro Iesato, Kentaro Yuda, Kelvin Teo Yi Chong, Xue Tan, Toshinori Murata, Takayuki Shindo, Yasuo Yanagi


Effect of leaking capillaries and microaneurysms in the perifoveal capillary network on resolution of macular edema by anti-vascular endothelial growth factor treatment
Japanese Journal of Ophthalmology,60:86-94 2016
Author:Yasuhiro Iesato, Akira Imai, Takao Hirano, Yuichi Toriyama, Toshinori Murata


Correspondence to RANIBIZUMAB PLUS PROMPT OR DEFERRED LASER FOR DIABETIC MACULAR EDEMA IN EYES WITH VITRECTOMY BEFORE ANTI-VASCULAR ENDOTHELIAL GROWTH FACTOR THERAPY.
Retina,36(3):22-23 2016
Author:Michael W.Stewart, Maurice B. Landers, David J. Browning, Toshinori Murata, Masahito Ohji, Jerzy Nawrocki, Jay K. Chhablani


レーザーで治す糖尿病黄斑浮腫(DME) これが本当のグリッドだ!
知っているようで知らない新しい糖尿病網膜症診療,:230-239 2016
Author:平野 隆雄, 村田敏規


Physiological significance of recombination-activating gene 1 in neuronal death, especially optic neuropathy.
FEBS J.,282(1):129-141 2015
Author:Hirano T, Murata T, Hayashi T.


En face swept-source optical coherence tomography detecting thinning of inner retinal layers as an indicator of capillary nonperfusion
Eur J Ophthalmol,255(2):153-158 2015
Author:Imai A, Toriyama Y, Iesato Y, Hirano T, Murata T


パターンスキャンレーザーを用いた光凝固の際の網膜前出血合併について
日本糖尿病眼学会誌,19:76-78 2014
Author:平野隆雄,山本裕香,時光元温,千葉大,京本敏行,村田敏規


B-mode超音波検査が鑑別に有用であったcapsular block syndromeの1例
臨床眼科,68:1455-1458 2014
Author:山本裕香,宮原照良,増尾史織,村田暢子,村田敏規


糖尿病網膜症
臨牀と研究,91:1146-1150 2014
Author:京本敏行,平野隆雄,村田敏規


眼疾患
臨牀と研究,91:515-520 2014
Author:朱さゆり,村田敏規


糖尿病網膜症の光凝固の進歩
あたらしい眼科,31:1083-1088 2014
Author:平野隆雄,村田敏規


薬物治療と網膜光凝固の併用による糖尿病黄斑浮腫治療
眼薬理,28:62-66 2014
Author:平野隆雄,村田敏規


倒乱視白内障に対し過矯正Toric IOLを用いた乱視矯正の検討
臨床眼科,68:813-817 2014
Author:平林一貴,保谷卓男,赤羽圭太,金児由美,菊島渉,鳥山祐一,京本敏行,村田敏規


特集 糖尿病黄斑浮腫 4. 黄斑浮腫治療におけるレーザー光凝固治療
眼科,56:475-482 2014
Author:平野隆雄,村田敏規


緑内障眼における黄斑部ganglion cell complex厚と視力との相関
眼科,56:425-432 2014
Author:前沢千種,宮原照良,山本裕香,黒川徹,村田敏規


網膜硝子体 糖尿病網膜症の治療
眼科,56:142-148 2014
Author:平野隆雄,村田敏規


マルチカラースキャンレーザー光凝固装置 MC-500Vixi®(NIDEK)
あたらしい眼科,31:11-17 2014
Author:平野隆雄,村田敏規


網膜レーザー光凝固治療の進化
あたらしい眼科,31:1-1 2014
Author:村田敏規,小椋祐一郎


光凝固
臨床眼科,68:20-26 2014
Author:平野隆雄,村田敏規


Quick Referral and Urgent Surgery to Preempt Foveal Detachment in Retinal Detachment Repair
Asia Pac J Ophthalmol,3:141-145 2014
Author:Kikushima W, Imai A, Hirano T, Iesato Y, Toriyama Y, Murata M, Murata T


Urgent Vitrectomy/Phacovitrectomy for Bullous Macula-Off Retinal Detachemnt: Implications for Optimal Timing of Surgery
Asia Pac J Ophthalmol,3:36-40 2014
Author:Kikushima W, Imai A, Miyahara T, Kurokawa T, Murata T


Multicolor pattern scan laser for diabetic retinopathy with cataract
Int J Ophthalmol,7:673-676 2014
Author:Hirano T, Iesato Y, Murata T


Correlation between diabetic retinopathy severity and elevated skin autofluorescene as a marker of advanced glycation end-product accumulation in type 2 diabetic patients
J Diabetes Complications,28:729-734 2014
Author:Hirano T, Iesato Y, Toriyama Y, Imai A, Chiba D, Murata T


Detection of Fovea-Threatening Diabetic Macular Edema by Optical Coherence Tomography to Maintain Good Vision by Prophylactic Treatment
Ophthalmic Res,52:65-73 2014
Author:Hirano T, Iesato Y, Toriyama Y, Imai A, Murata T


Effect of Laser Wavelength on Delivering Appropriate Laser Burns through the Opaque Lens Using a Pattern Scan Laser
Ophthalmic Res,51:204-209 2014
Author:Hirano T, Iesato Y, Imai A, Toriyama Y, Kikushima W, Murata T


Vitrectomy for DME Without Macular Traction
Retinal Physician,10:61-64 2013
Author:Hirano T, Murata T


Characteristics of shaken baby syndrome in a regional Japanese children’s hospital
Jpn J Ophthalmol,57:568-572 2013
Author:Mori K, Kitazawa N, , Murata T et al.


Adrenomedullin-RAMP2 System Is Crucially Involved in Retinal Angiogenesis
Am J Pathol,182:2380-2390 2013
Author:Iesato Y, Murata T, Shindo T et al.


矯正視力1.0を目指せる糖尿病黄斑浮腫の治療
日本の眼科,84:1354-1359 2013
Author:村田 敏規


Treatment for Diabetic Macular Edema in Japan
Retina Today,May/June:45-48 2013
Author:村田 敏規


Age-related decrease of the retinal vasculature area identified with a novel computer-aided analysis system
Tohoku J Exp Med,228(3):229-237 2012
Author:Yamamoto Y, Yamamoto Y, Marugame A, Ogura M, Saito A, Ohta K, Fukumoto M, Murata T


戦略企画会議から 眼科専門医の医師像について
日本眼科学会雑誌,115:1062-1063 2011
Author:村田敏規


多発隅角結節をきたしたサルコイドーシスの1例
眼科臨床紀要,4:1082-1086 2011
Author:菊島渉、黒川徹、時光元温、村田敏規、相澤万象


トーリック眼内レンズの術後短期成績
眼科臨床紀要,4:846-850 2011
Author:鳥山佑一、今井章、金子由美、保谷卓男、平野隆雄、京本敏行、村田敏規


戦略企画会議から 日本眼科学会専門医制度第5回指導医講習会を終えて
日本眼科学会雑誌,115:853-854 2011
Author:村田 敏規


糖尿病網膜症における網膜レーザー凝固
Diabetes Frontier,22:385-389 2011
Author:村田敏規


第64回日本臨床眼科学会印象記  一般口演「眼腫瘍(1)」
眼科,53:525-526 2011
Author:村田敏規


Development of spontanieous neuropathy in NF-kBp50-deficient mice by calcineurin-signal involving impaired NF-kB activation
Mol Vis,17:2157-2170 2011
Author:Tomoko Nakamura-Yanagidaira, Yasuko Takahashi, Kenji Sano, Toshinori Murata, Takuma Hayashi


Tissue-type plasminogen activator-assisted drainage of suprachoroidal hemorrhage showing a kissing configuration
Jpn J Ophthalmol,55:431-432 2011
Author:Toshinori Murata, Wataru Kikushima, Akira Imai, Yuichi Toriyama, Motoharu Tokimitsu, Toru Kurokawa


Central retinal vein occlusion in hypertensive patients with chronic hepatitis C treated with interferon alpha and ribavirin
JAPANESE JOURNAL OF OPHTHALMOLOGY,52(6):511-513 2008
Author:Murata, M; Tamura, Y; Ohsawa, M; Hirano, T; Matsuo, T; Murata, T


Glutaraldehyde is an effective cross-linker for production of antibodies against advanced glycation end-products
JOURNAL OF IMMUNOLOGICAL METHODS,334(1-2):82-90 2008
Author:Mera, K; Nagai, M; Brock, JWC; Fujiwara, Y; Murata, T; Maruyama, T; Baynes, JW; Otagiri, M; Nagai, R


Vasoproliferative tumors of the retina secondary to ocular toxocariasis
CANADIAN JOURNAL OF OPHTHALMOLOGY-JOURNAL CANADIEN D OPHTALMOLOGIE,42(5):758-759 2007
Author:Mori, K; Ohta, K; Murata, T


Expression of c-Jun and Bcl-2 family proteins in apoptotic photoreceptors of RCS rats
JAPANESE JOURNAL OF OPHTHALMOLOGY,50(2):121-127 2006
Author:Katai, N; Yanagidaira, T; Senda, N; Murata, T; Yoshimura, N


A preclinical safety study of simian immunodeficiency virus (SIVagm)-based lentiviral vector for retinal gene transfer in non-human primates
JOURNAL OF GENE MEDICINE,8(3):382-382 2006
Author:Ikeda, Y; Miyazaki, M; Kono, R; Yonemitsu, Y; Murata, T; Goto, Y; Tabata, T; Terao, K; Ueda, Y; Hasegawa, M; Tobimatsu, S; Ishibashi, T; Sueishi, K


Rubeosis iridis after bilateral cataract surgery and its spontaneous regression in a patient with myotonic dystrophy
JOURNAL OF CATARACT AND REFRACTIVE SURGERY,32(5):873-874 2006
Author:Kuroda, T; Katai, N; Yoshida, N; Murata, T


遺伝子診療学―遺伝子診断の進歩と遺伝子治療の展望― A.遺伝子診断 (genetic diagnosis)(遺伝子学的検査genetic testing,遺伝子検査gene-based testing,核酸検査nucleic acid-based testing) 眼科疾患
日本臨床,63:264-268 2005
Author:吉田茂生,山地陽子,桑原留美,村田敏規


白内障手術後のcandida parapsilosisによる真菌性眼内炎の1例
臨床眼科,59:459-462 2005
Author:尾崎 秀,野田和宏,永富智浩,藤田ひかる,木村純子,村田敏規,石橋達朗


九州厚生年金病院におけるアルゴンレーザーを用いた網膜剥離予防手術の検討
あたらしい眼科,22:1141-1144 2005
Author:永富智浩,尾崎 秀,野田和宏,藤田ひかる,木村純子,村田敏規,石橋達朗


糖尿病網膜症の新しい治療とその現状
日本醫事新報,4252:6-10 2005
Author:京本敏行,片井直達,村田敏規


硝子体手術の進歩
糖尿病,48:729-731 2005
Author:太田浩一,村田敏規


最近の硝子体手術と網膜症:トリアムシノロンを用いた硝子体手術
日本の眼科,76:935-938 2005
Author:村田敏規


Ruptured distal middle cerebral artery aneurysm
J Neurosurg,100:384-388 2004
Author:Horiuchi T, Tanaka Y, Takasawa H, Murata T, Yako T, Hongo K


Twodifferent mechanisms are involved in the extremely high-level benzalkonium chloride resistance of a Pseudomonas fluorescens strain
Microbiol Immunol,47:709-715 2003
Author:Nagai K, Murata T, Ohta S, Zenda H, Ohnishi M, Hayashi T