書籍等出版物 Thin Carbon Fiber Web that Functions as a Scaffold for Tissue Regeneration., In Advances in Medicine&Biology 11 , 301-310 Nova Science Publishers Inc 2011 Author:Saito N, Aoki K, Usui Y, Shimizu M, Hara K, Narita N, Ogihara N, Nakamura K, Ishigaki N,Kato H, Haniu H, Kim C, Taruta S, Kim YA, Endo M.
Application of carbon nanotubes on scaffolds for bone tissue regeneration., Bone Regeneration: Growth Factors, Augmentation Procedures and Tissue Engineering Applications , 275-284 Nova Science Publishers 2010 Author:Saito N, Usui Y, Aoki K, Narita N, Shimizu M, Hara K, Ogihara N, Nakamura K, Ishigaki N, Kato H, Haniu H, Taruta S, Endo M.
論文 Evaluation of MC3T3-E1 Cell Osteogenesis in Different Cell Culture Media International Journal of Molecular Sciences,22(14):7752 2021(Jul.) Author:Izumiya M, Haniu M, Ueda K, Ishida H, Ma C, Ideta H, Sobajima A, Ueshiba K, Uemura T, Saito N, Haniu H.
The Combined Effects of Lysophospholipids against Lipopolysaccharide-induced Inflammation and Oxidative Stress in Microglial Cells. J Oleo Sci.,70:947-954 2021(Jul.) Author:Tsukahara T, Hara H, Haniu H, Matsuda Y.
Abundant oleoyl-lysophosphatidylethanolamine in brain stimulates neurite outgrowth and protects against glutamate toxicity in cultured cortical neurons. J Biochem. 2021(Apr.) Author:69. Hisano K, Yoshida H, Kawase S, Mimura T, Haniu H, Tsukahara T, Kurihara T, Matsuda Y, Saito N, Uemura T.
Isolated lymphatic vessel lumen perfusion system for assessing nanomaterial movements and nanomaterial-induced responses in lymphatic vessels. Nano Today.,36(101018) 2021(Feb.) Author:Kuroda C, Ajima K, Ueda K, Sobajima A, Yoshida K, Kamanaka T, Sasaki J, Ishida H, Haniu H, Okamoto M, Aoki K. Kato H, Saito N.
Structurally different lysophosphatidylethanolamine species stimulate neurite outgrowth in cultured cortical neurons via distinct G-protein-coupled receptors and signaling cascades. Biochem Biophys Res Commun.,534:179-185 2021(Jan.) Author:Hisano K, Kawase S, Mimura T, Yoshida H, Yamada H, Haniu H, Tsukahara T, Kurihara T, Matsuda Y, Saito N, Uemura T.
Multiwall Carbon Nanotube Composites as Artificial Joint Materials. ACS Biomater. Sci. Eng.,6:7032-7040 2020(Dec.) Author:Sobajima A, Okihara T, Moriyama S, Nishimura N, Osawa T, Miyamae K, Haniu H, Aoki K, Tanaka M, Usui Y, Sako K, Kato H, Saito N.
Oral administration of porcine liver decomposition product for 4 weeks enhances visual memory and delayed recall in healthy adults over 40 years of age: A randomized, double-blind, placebo-controlled study. Exp Gerontol.,141:111064 2020(Nov.) Author:Matsuda Y, Haniu H, Tsukahara T, Uemura T, Inoue T, Sako KI, Kojima J, Mori T, Sato K.
Carbon nanotube-based biomaterials for orthopaedic applications. J Mater Chem B.,8:9227-9238 2020(Oct.) Author:Aoki K, Ogihara N, Tanaka M, Haniu H, Saito N.
Therapeutic Potential of Porcine Liver Decomposition Product: New Insights and Perspectives for Microglia-Mediated Neuroinflammation in Neurodegenerative Diseases. Biomedicines.,8:446 2020(Oct.) Author:Tsukahara T, Haniu H, Uemura T, Matsuda Y.
Carbon fibers for treatment of cancer metastasis in bone. RSC Adv.,10:33071-33079 2020(Sep.) Author:Kamanaka T, Haniu H, Tanaka M, Takizawa T, Aoki K, Okamoto M, Sobajima A, Yoshida K, Ideta H, Mimura T, Ishida H, Ueda K, Uemura T, Kim JH, Kim YA, Kato H, Saito N.
Cellular Responses of Human Lymphatic Endothelial Cells to Carbon Nanomaterials. Nanomaterials (Basel).,10:1374 2020 Author:Sano M, Izumiya M, Haniu H*, Ueda K, Konishi K, Ishida H, Kuroda C, Uemura T, Aoki K, Matsuda Y, Saito N.
Applications of Carbon Nanotubes in Bone Regenerative Medicine. Nanomaterials (Basel).,10:659 2020 Author:Tanaka M, Aoki K, Haniu H, Kamanaka T, Takizawa T, Sobajima A, Yoshida K, Okamoto M, Kato H, Saito N.
The Use of Electrospun Organic and Carbon Nanofibers in Bone Regeneration. Nanomaterials (Basel).,10:562 2020 Author:Aoki K, Haniu H, Kim YA, Saito N.
Anti-PD-1 antibody decreases tumor-infiltrating regulatory T cells. BMC Cancer,20:25 2020 Author:Yoshida K, Okamoto M, Sasaki J, Kuroda C, Ishida H, Ueda K, Ideta H, Kamanaka T, Sobajima A, Takizawa T, Tanaka M, Aoki K, Uemura T, Kato H, Haniu H, Saito N.
Organ accumulation and carcinogenicity of highly dispersed multi-walled carbon nanotubes administered intravenously in transgenic rasH2 mice. Int J Nanomedicine.,14:6465-80 2019 Author:Sobajima A, Haniu H, Nomura H, Tanaka M, Takizawa T, Kamanaka T, Aoki K, Okamoto M, Yoshida K, Sasaki J, Ajima K, Kuroda C, Ishida H, Okano S, Ueda K, Kato H, Saito N.
In Vitro and In Vivo Evaluation of Starfish Bone-Derived β-Tricalcium Phosphate as a Bone Substitute Material. Materials (Basel).,12:E1881 2019 Author:Ishida H, Haniu H, Takeuchi A, Ueda K, Sano M, Tanaka M, Takizawa T, Sobajima A, Kamanaka T, Saito N.
Clinical outcome of osteosarcoma and its correlation with programmed death-ligand 1 and T cell activation markers. Oncotargets Ther.,12:2513-2518 2019 Author:Yoshida K, Okamoto M, Sasaki J, Kuroda C, Ishida H, Ueda K, Okano S, Ideta H, Kamanaka T, Sobajima A, Takizawa T, Kito M, Aoki K, Uemura T, Haniu H, Kato H, Saito N.
Different aggregation and shape characteristics of carbon materials affect biological responses in RAW264 cells INTERNATIONAL JOURNAL OF NANOMEDICINE,13:6079-6088 2018(Oct. 05) Author:Kuroda Chika, Ueda Katsuya, Haniu Hisao, Ishida Haruka, Okano Satomi, Takizawa Takashi, Sobajima Atsushi, Kamanaka Takayuki, Yoshida Kazushige, Okamoto Masanori, Tsukahara Tamotsu, Matsuda Yoshikazu, Aoki Kaoru, Kato Hiroyuki, Saito Naoto
The AGP-PPARγ axis promotes oxidative stress and diabetic endothelial cell dysfunction. Mol Cell Endocrinol.,473:100-113 2018 Author:Tsukahara R, Haniu H, Matsuda Y, Tsukahara T.
Alkyl-glycerophosphate-mediated C-C motif chemokine 2 secretion induces oxidative stress via increased PPARγ activation in human umbilical vein endothelial cells. Biomed Pharmacother.,106:686-691 2018 Author:Tsukahara T, Yamagishi S, Matsuda Y, Haniu H.
Titanium fiber plates for bone tissue repair. Adv Mater.,30:1703608 2018 Author:Takizawa T, Nakayama N, Haniu H, Aoki K, Okamoto M, Nomura H, Tanaka M, Sobajima A, Yoshida K, Kamanaka T, Ajima K, Oishi A, Kuroda C, Ishida H, Okano S, Kobayashi S, Kato H, Saito N.
Lysophospholipid-related diseases and PPARγ signaling pathway. Int J Mol Sci.,18:2730 2017 Author:Tsukahara T, Matsuda Y, Haniu H.
Lysophosphatidic acid signaling regulates the KLF9-PPARγ axis in human induced pluripotent stem cell-derived neurons. Biochem Biophys Res Commun.,491:223-227 2017 Author:Tsukahara T, Yamagishi S, Matsuda Y, Haniu H.
In Vitro and In Vivo Evaluation of a Three-Dimensional Porous Multi-Walled Carbon Nanotube Scaffold for Bone Regeneration. Nanomaterials,7:46 2017 Author:Tanaka M, Sato Y, Zhang M, Haniu H, Okamoto M, Aoki K, Takizawa T, Yoshida K, Sobajima A, Kamanaka T, Kato H, Saito N.
A three-dimensional block structure consisting exclusively of carbon nanotubes serving as bone regeneration scaffold and as bone defect filler. PLoS One,12:e0172601 2017 Author:Tanaka M, Sato Y, Haniu H, Nomura H, Kobayashi S, Takanashi S, Okamoto M, Takizawa T, Aoki K, Usui Y, Oishi A, Kato H, Saito N.
Physico-Chemical, in vitro, and in vivo evaluation of a 3D unidirectional porous hydroxyapatite scaffold for bone regeneration. Materials (Basel).,10:33 2017 Author:Tanaka M, Haniu H,Kamanaka T,Takizawa T, Sobajima A, Yoshida K, Aoki K, Okamoto M, Kato H, Saito N.
The dispersion state of tangled multi-walled carbon nanotubes affects their cytotoxicity. Nanomaterials,6 2016 Author:Kuroda C, Haniu H, Ajima K, Tanaka M, Sobajima A, Ishida H, Tsukahara T, Matsuda Y, Aoki K, Kato H, Saito N.
Short-term treatment with a 2-carba analog of cyclic phosphatidic acid induces lowering of plasma cholesterol levels in ApoE-deficient mice. Biochem Biophys Res Commun.,473:107-113 2016 Author:Tsukahara T, Haniu H, Matsuda Y, Murakami-Murofushi K.
An advanced in situ imaging method using heavy metal-doped hollow tubes to evaluate the biokinetics of carbon nanotubes in vivo NPG ASIA MATERIALS,7 2015(Jul.) Author:Kobayashi, Shinsuke; Tsuruoka, Shuji; Usui, Yuki; Haniu, Hisao; Aoki, Kaoru; Takanashi, Seiji; Okamoto, Masanori; Nomura, Hiroki; Tanaka, Manabu; Aiso, Shigetoshi; Saito, Misae; Kato, Hiroyuki; Saito, Naoto;
CYCLIC PHOSPHATIDIC ACID INDUCES G(0/)G(1) ARREST, INHIBITS AKT PHOSPHORYLATION, AND DOWNREGULATES CYCLIN D1 EXPRESSION IN COLORECTAL CANCER CELLS CELLULAR & MOLECULAR BIOLOGY LETTERS,20(1):38-47 2015(Mar.) Author:Tsukahara, T; Haniu, H; Matsuda, Y
The Role of Autophagy as a Mechanism of Toxicity Induced by Multi-Walled Carbon Nanotubes in Human Lung Cells INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES,16(1):40-48 2015(Jan.) Author:Tsukahara, Tamotsu; Matsuda, Yoshikazu; Haniu, Hisao
Cyclic phosphatidic acid inhibits the secretion of vascular endothelial growth factor from diabetic human coronary artery endothelial cells through peroxisome proliferator-activated receptor gamma. Mol Cell Endocrinol.,412:320-329 2015 Author:Tsukahara T, Tsukahara R, Haniu H, Matsuda Y, Murakami-Murofushi K.
Specific biological responses of the synovial membrane to carbon nanotubes SCIENTIFIC REPORTS,5 2015 Author:Nomura, Hiroki; Takanashi, Seiji; Tanaka, Manabu; Haniu, Hisao; Aoki, Kaoru; Okamoto, Masanori; Kobayashi, Shinsuke; Takizawa, Takashi; Usui, Yuki; Oishi, Ayumu; Kato, Hiroyuki; Saito, Naoto;
Two-Dimensional Gel-Based Protein Standardization Verified by Western Blot Analysis Methods in Molecular Biology ,1312:473-479 2015 Author:Haniu, Hisao; Watanabe, Daisuke; Kawashima, Yusuke; Matsumoto, Hiroyuki
Endocytosis of Multiwalled Carbon Nanotubes in Bronchial Epithelial and Mesothelial Cells BIOMED RESEARCH INTERNATIONAL,2015:793186 2015 Author:Maruyama, K; Haniu, H; Saito, N; Matsuda, Y; Tsukahara, T; Kobayashi, S; Tanaka, M; Aoki, K; Takanashi, S; Okamoto, M; Kato, H
Cyclic Phosphatidic Acid Inhibits Alkyl-Glycerophosphate-Induced Downregulation of Histone Deacetylase 2 Expression and Suppresses the Inflammatory Response in Human Coronary Artery Endothelial Cells INTERNATIONAL JOURNAL OF MEDICAL SCIENCES,11(9):955-961 2014 Author:Tsukahara, Tamotsu; Haniu, Hisao; Matsuda, Yoshikazu
Heart-type fatty-acid-binding protein (FABP3) is a lysophosphatidic acid-binding protein in human coronary artery endothelial cells FEBS OPEN BIO,4:947-951 2014 Author:Tsukahara, Ryoko; Haniu, Hisao; Matsuda, Yoshikazu; Tsukahara, Tamotsu
Biological responses according to the shape and size of carbon nanotubes in BEAS-2B and MESO-1 cells INTERNATIONAL JOURNAL OF NANOMEDICINE,9:1979-1990 2014 Author:Haniu, H; Saito, N; Matsuda, Y; Tsukahara, T; Usui, Y; Maruyama, K; Takanashi, S; Aoki, K; Kobayashi, S; Nomura, H; Tanaka, M; Okamoto, M; Kato, H
Cyclic Phosphatidic Acid Stimulates cAMP Production and Inhibits Growth in Human Colon Cancer Cells PLOS ONE,8(11):e81139 2013(Nov.) Author:Tsukahara, T; Matsuda, Y; Haniu, H
Highly purified, multi-wall carbon nanotubes induce light-chain 3B expression in human lung cells BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS,440(2):348-353 2013(Oct. 18) Author:Tsukahara Tamotsu, Matsuda Yoshikazu, Usui Yuki, Haniu Hisao
Culture medium type affects endocytosis of multi-walled carbon nanotubes in BEAS-2B cells and subsequent biological response Toxicology in Vitro,27(6):1679-1685 2013(Sep.) Author:Haniu, Hisao; Saito, Naoto; Matsuda, Yoshikazu; Tsukahara, Tamotsu; Maruyama, Kayo; Usui, Yuki; Aoki, Kaoru; Takanashi, Seiji; Kobayashi, Shinsuke; Nomura, Hiroki; Okamoto, Masanori; Shimizu, Masayuki; Kato, Hiroyuki
PSF Knockdown Enhances Apoptosis via Downregulation of LC3B in Human Colon Cancer Cells BIOMED RESEARCH INTERNATIONAL,2013:204973 2013 Author:Tsukahara, T; Matsuda, Y; Haniu, H
Effect of alkyl glycerophosphate on the activation of peroxisome proliferator-activated receptor gamma and glucose uptake in C2C12 cells. Biochem Biophys Res Commun.,433:281-285 2013 Author:Tsukahara T, Haniu H, Matsuda Y.
PTB-associated splicing factor (PSF) is a PPARγ-binding protein and growth regulator of colon cancer cells. PLoS One,8:e58749 2013 Author:Tsukahara T, Haniu H, Matsuda Y.
Carbon Nanotubes Innovate on Medical Technology. Med Chem.,2:105 2012 Author:Usui Y, Haniu H, Tsuruoka S, Saito N.
Lysophosphatidic Acid Stimulates MCP-1 Secretion From C2C12 Myocytes. ISRN Inflamm.,2012:983420 2012 Author:Tsukahara T, Haniu H.
Peroxisome proliferator-activated receptor gamma overexpression suppresses proliferation of human colon cancer cells. Biochem Biophys Res Commun.,424:524-529 2012 Author:Tsukahara T, Haniu H.
Two-dimensional gel electrophoresis: glass tube-based IEF followed by SDS-PAGE. Methods Mol Biol.,869:267-273 2012 Author:Matsumoto H, Haniu H, Kurien BT, Komori N.
Carcinogenicity evaluation for the application of carbon nanotubes as biomaterials in rasH2 mice. Sci Rep.,2:498 2012 Author:Takanashi S, Hara K, Aoki K, Usui Y, Shimizu M, Haniu H, Ogihara N, Ishigaki N, Nakamura K, Okamoto M, Kobayashi S, Kato H, Sano K, Nishimura N, Tsutsumi H, Machida K, Saito N.
Carbon nanotubes induce bone calcification by bidirectional interaction with osteoblasts. Adv Mater.,24:2176-2185 2012 Author:Shimizu M, Kobayashi Y, Mizoguchi T, Nakamura H, Kawahara I, Narita N, Usui Y, Aoki K, Hara K, Haniu H, Ogihara N, Ishigaki N, Nakamura K, Kato H, Kawakubo M, Dohi Y, Taruta S, Kim YA, Endo M, Ozawa H, Udagawa N, Takahashi N, Saito N.
Biocompatibility and bone tissue compatibility of alumina ceramics reinforced with carbon nanotubes. Nanomedicine (Lond).,7:981-993 2012 Author:Ogihara N, Usui Y, Aoki K, Shimizu M, Narita N, Hara K, Nakamura K, Ishigaki N, Takanashi S, Okamoto M, Kato H, Haniu H, Ogiwara N, Nakayama N, Taruta S, Saito N.
Cellular cytotoxic response induced by highly purified multi-wall carbon nanotube in human lung cells Molecular and Cellular Biochemistry,352(1-2):57-63 2011(Jun.) Author:Tsukahara, Tamotsu; Haniu, Hisao
Nanoparticle-mediated intracellular lipid accumulation during C2C12 cell differentiation BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS,406(4):558-563 2011(Mar.) Author:Tsukahara, Tamotsu; Haniu, Hisao
Evaluation of CNT toxicity in comparison to tattoo ink nanoparticles for use as a biomaterial. Mater Today.,14:434-440 2011 Author:Hara K, Kaoru Aoki K, Usui Y, Shimizu M, Narita N, Ogihara N, Nakamura K, Ishigaki N, Sano K, Haniu H, Kato H, Nishimura N, Kim YA, Taruta S, Saito N.
The Application of Proteomics to PK-PD Modeling and Simulation. J Bioequiv Availab,2011:S2-002 2011 Author:Sako K, Haniu H, Hasegawa M, et al
Application of carbon fibers to biomaterials: A new era of nano-level control of carbon fibers after 30-years of development CHEMICAL SOCIETY REVIEWS,40(7):3824-3834 2011 Author:Saito, Naoto; Aoki, Kaoru; Usui, Yuki; Shimizu, Masayuki; Hara, Kazuo; Narita, Nobuyo; Ogihara, Nobuhide; Nakamura, Koichi; Ishigaki, Norio; Kato, Hiroyuki; Haniu, Hisao; Taruta, Seiichi; Kim, Yoong Ahm; Endo, Morinobu
Proteomics-based safety evaluation of multi-walled carbon nanotubes Toxicology and Applied Pharmacology,242(3):256-262 2010(Feb.) Author:Haniu, H; Matsuda, Y; Takeuchi, K; Kim, YA; Hayashi, T; Endo, M
Effect of Lecithin: Cholesterol Acyltransferase on the Formation of Cross-linked Apolipoprotein AI. J Ana Bio-Sci,33:151-160 2010 Author:Kurosaki Y, Ikeya H, Haniu H, et al
Potential of a Novel Safety Evaluation of Nanomaterials Using a Proteomic Approach Journal of health science,55(3):428-434 2009(Jun.) Author:Haniu,Hisao; Matsuda,Yoshikazu; Takeuchi,Kenji
Identification of 4-hydroxynonenal-modified retinal proteins induced by photooxidative stress prior to retinal degeneration. Free Radic Biol Med,41:1847-1859 2006 Author:Tanito, M; Haniu, H; Elliott,MH; Singh, AK; Matsumoto, H; Anderson, RE
Role of systemic T-cells and histopathological aspects after subcutaneous implantation of various carbon nanotubes in mice CARBON,44(6):1079-1092 2006 Author:Koyama, S; Endo, M; Kim, YA; Hayashi, T; Yanagisawa, T; Osaka, K; Koyama, H; Haniu, H; Kuroiwa, N
Proteomic trajectory mapping of biological transformation: Application to developmental mouse retina PROTEOMICS,6(11):3251-3261 2006 Author:Haniu, H; Komori, N; Takemori, N; Singh, A; Ash, JD; Matsumoto, H
Medical application of carbon-nanotube-fitted nanocomposites: The microcatheter SMALL,2(12):1406-1411 2006 Author:Koyama, S; Haniu, H; Osaka, K; Koyama, H; Kuroiwa, N; Endo, M; Kim, YA; Hayashi, T
Different tissue reactions to activated carbon fivers - Pathological and immunological findings after subcutaneous implantation Mol Cryst Liq Cryst,388:109-115 2002 Author:Koyama S, Tanaka S, Yamaguchi Y, Haniu H, Konishi G, Koyama H
Inhibition of cell cycle and induction of apoptosis due to modified C60 on HL-60 promyelocytic leukemic cells and it's macrophage-like cells Mol Cryst Liq Cryst,386:21-24 2002 Author:Koyama S, Haniu H, Tanaka S, Yamaguchi Y, Konishi G, Koyama H
Cell growing with activated carbon fivers - Significances of porous size Mol Cryst Liq Cryst,388:173-176 2002 Author:Koyama S, Haniu H, Takeichi T, Tanaka S, Yamaguchi Y, Konishi G, Koyama H
Effect of ONO-5046, a specific neutrophil elastase inhibitor, on the phorbol myristate acetate-induced injury in isolated dog lung EXPERIMENTAL LUNG RESEARCH,25(1):55-67 1999 Author:Wang, HG; Shibamoto, T; Miyahara, T; Haniu, H; Tanaka, S; Fujimoto, K; Honda, T; Kubo, K; Koyama, S
In vitro and in vivo antiturnor activity of Yoshixol(TR) against murine L1210 leukemic cells GENERAL PHARMACOLOGY,33(2):179-186 1999 Author:Tanaka, S; Koyama, S; Haniu, H; Yamaguchi, Y; Motoyoshiya, J
Yoshixol(TR) inhibits B16 melanoma cell growth in vivo and induces apoptosis-like (quantum thermodynamic) cell death GENERAL PHARMACOLOGY,33(2):161-172 1999 Author:Koyama, S; Tanaka, S; Haniu, H; Yamaguchi, Y; Motoyoshiya, J
Presinusoidal vessels predominantly contract in response to norepinephrine, histamine, and KC1 in rabbit Liver JOURNAL OF APPLIED PHYSIOLOGY,87(4):1404-1412 1999 Author:Shibamoto, T; Wang, HG; Miyahara, T; Tanaka, S; Haniu, H; Koyama, S
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