留学歴 2016-2018 , GI Clinical Fellow, Laboratory Medicine, Mount Sinai Hospital, University of Toronto
研究活動業績
研究業績（著書・ 発表論文等）
論文 Low-grade mixed neuroendocrine-non-neuroendocrine neoplasm of the extrahepatic bile duct: A rare tumour with 11 years' follow-up before surgery PATHOLOGY INTERNATIONAL,73(4):173-176 2023(Apr.) Author:Kubota, Koji; Sato, Yoshinori; Iwaya, Mai; Notake, Tsuyoshi; Shimizu, Akira; Iguchi, Takuya; Uehara, Takeshi; Ota, Hiroyoshi; Soejima, Yuji; Keywords:bile duct; low grade; mixed neuroendocrine-non-neuroendocrine neoplasm;
Number and distribution of eosinophils and lymphocytes in the Japanese pediatric gastrointestinal tract: in search of a definition for "abnormally increased eosinophils" WORLD JOURNAL OF PEDIATRICS,19(3):251-260 2023(Mar.) Author:Iwaya, Mai; Kobayashi, Shota; Nakayama, Yoshiko; Kato, Sawako; Kurasawa, Shingo; Sado, Tomomitsu; Iwaya, Yugo; Uehara, Takeshi; Ota, Hiroyoshi; Keywords:Eosinophil; Gastrointestinal tract; Japanese; Lymphocyte; Normal; Pediatrics;
CD8(+) Lymphocyte Infiltration Is a Specific Feature of Colitis Induced by Immune Checkpoint Inhibitors DIGESTIVE DISEASES AND SCIENCES,68(2):451-459 2023(Feb.) Author:Takahashi, Yoshiyuki; Nagaya, Tadanobu; Iwaya, Yugo; Okamura, Takuma; Hirayama, Atsuhiro; Iwaya, Mai; Uehara, Takeshi; Umemura, Takeji; Keywords:Immune checkpoint inhibitor; Immune-related adverse event; Colitis; CD8(+) lymphocytes; CD4(+) lymphocytes;
High expression of LGR6 is a poor prognostic factor in esophageal carcinoma PATHOLOGY RESEARCH AND PRACTICE,242:154312 2023(Feb.) Author:Ehara, Takehito; Uehara, Takeshi; Yoshizawa, Takahiro; Kinugawa, Yasuhiro; Nakajima, Tomoyuki; Kobayashi, Shota; Asaka, Shiho; Iwaya, Mai; Nagaya, Tadanobu; Kitazawa, Masato; Ota, Hiroyoshi; Soejima, Yuji; Keywords:Leucine-rich repeat-containing G-protein-coupled receptor 6; Esophageal squamous cell carcinoma; RNA in situ hybridization;
Surgical revascularization for quasi-moyamoya disease associated with polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, and skin changes (POEMS) syndrome: a case report and literature review NAGOYA JOURNAL OF MEDICAL SCIENCE,85(1):141-149 2023(Feb.) Author:Kubota, Yuki; Hanaoka, Yoshiki; Koyama, Jun-ichi; Takahashi, Yusuke; Katoh, Nagaaki; Iwaya, Mai; Fujii, Yu; Ogiwara, Toshihiro; Horiuchi, Tetsuyoshi; Keywords:Polyneuropathy; organomegaly; endocrinopathy; monoclonal gammopathy; and skin changes; cerebral infarction; cerebral revascularization; Crow-Fukase syndrome; STA-MCA anastomosis; vascular endothelial growth factor;
Serum positivity of serum anti-tissue transglutaminase immunoglobulin A antibodies in Japanese children with inflammatory bowel disease PEDIATRICS INTERNATIONAL,65(1):e15485 2023(Jan.) Author:Kurasawa, Shingo; Sado, Tomomitsu; Kato, Sawako; Iwaya, Mai; Nakayama, Yoshiko; Keywords:anti-tissue transglutaminase IgA antibody; celiac disease; child; inflammatory bowel disease; subclinical celiac disease;
Hereditary diffuse gastric cancer in a Japanese family with CDH1 mutation three case reports DISCOVER ONCOLOGY,14(1):14 2023 Author:Muranaka, Futoshi; Kise, Emiko; Tokumaru, Shigeo; Kitazawa, Masato; Miyagawa, Yusuke; Suga, Tomoaki; Uehara, Takeshi; Iwaya, Mai; Kobayashi, Shota; Sato, Midori; Gomi, Daisuke; Yamada, Hidetaka; Sugimura, Haruhiko; Kosho, Tomoki; Soejima, Yuji; Koizumi, Tomonobu; Keywords:Hereditary Diffuse Gastric Cancer; E-cadherin; CDH1 mutations; Signet ring cell carcinoma; Esophagogastroduodenoscopy; Random and target biopsies; Total prophylactic gastrectomy;
Clinical features of pagetoid spread: Analysis of perianal lesions associated with anal canal adenocarcinoma and perianal primary extramammary Paget disease JOURNAL OF DERMATOLOGY 2023 Author:Kosano, Megumi; Kiniwa, Yukiko; Mikoshiba, Asuka; Iwaya, Mai; Okuyama, Ryuhei; Keywords:anal canal adenocarcinoma; extramammary Paget disease; pagetoid spread; raised appearance; symmetrical spread; well-defined margin;
Increased GS-II lectin binding and SATB2 downregulation are biological features for sessile serrated lesions and microvesicular hyperplastic polyps PATHOLOGY INTERNATIONAL 2023 Author:Matoba, Hisanori; Iwaya, Mai; Sato, Yoshiko; Kobayashi, Noriyasu; Takemura, Haruka; Kouno, Yusuke; Karasawa, Ayumi; Nakayama, Jun; Keywords:GS-II; microvesicular hyperplastic polyps; SATB2; sessile serrated lesions; beta GlcNAc;
Osteopontin expression in the invasive front stroma of colorectal adenocarcinoma is associated with tumor budding and prognosis PATHOLOGY RESEARCH AND PRACTICE,240:154190 2022(Dec.) Author:Nakajima, Tomoyuki; Uehara, Takeshi; Iwaya, Mai; Matsuda, Kazuyuki; Wada, Megumi; Nagaya, Tadanobu; Ehara, Takehito; Ota, Hiroyoshi; Keywords:Tumor budding; Colorectal carcinoma; Osteopontin; CD44v6;
Impact of DNA double-strand breaks on pancreaticobiliary maljunction carcinogenesis DIAGNOSTIC PATHOLOGY,16(1) 2021 Author:Kuraishi, Yasuhiro; Uehara, Takeshi; Muraki, Takashi; Iwaya, Mai; Kinugawa, Yasuhiro; Nakajima, Tomoyuki; Watanabe, Takayuki; Miyagawa, Yusuke; Umemura, Takeji; Keywords:Carcinogenesis; DNA double-strand break; Gallbladder; Pancreaticobiliary maljunction; gamma-H2AX;
Clinicopathological features of nodular gastritis in three classes of age HELICOBACTER 2021 Author:Kako, Satoko; Iwaya, Yugo; Nagaya, Tadanobu; Hara, Daichi; Okamura, Takuma; Iwaya, Mai; Kurasawa, Shingo; Kato, Sawako; Nakayama, Yoshiko; Akamatsu, Taiji; Umemura, Takeji; Keywords:classes of age; inflammation; nodular gastritis; pangastritis; updated Sydney System score;
Impact of DNA double-strand breaks on pancreaticobiliary maljunction carcinogenesis DIAGNOSTIC PATHOLOGY,16(1) 2021 Author:Kuraishi, Yasuhiro; Uehara, Takeshi; Muraki, Takashi; Iwaya, Mai; Kinugawa, Yasuhiro; Nakajima, Tomoyuki; Watanabe, Takayuki; Miyagawa, Yusuke; Umemura, Takeji; Keywords:Carcinogenesis; DNA double-strand break; Gallbladder; Pancreaticobiliary maljunction; gamma-H2AX;
Clinicopathological features of nodular gastritis in three classes of age HELICOBACTER 2021 Author:Kako, Satoko; Iwaya, Yugo; Nagaya, Tadanobu; Hara, Daichi; Okamura, Takuma; Iwaya, Mai; Kurasawa, Shingo; Kato, Sawako; Nakayama, Yoshiko; Akamatsu, Taiji; Umemura, Takeji; Keywords:classes of age; inflammation; nodular gastritis; pangastritis; updated Sydney System score;
Most colitis associated carcinomas lack expression of LGR5: a preliminary study with implications for unique pathways of carcinogenesis compared to sporadic colorectal carcinoma BMC CANCER,21(1) 2021 Author:Iwaya, Mai; Ota, Hiroyoshi; Nakajima, Tomoyuki; Uehara, Takeshi; Riddell, Robert; Conner, James; Keywords:Inflammatory bowel disease; Ulcerative colitis; Crohn's disease; Colitis associated colorectal carcinoma; LGR5;
Immunostaining With Immunoglobulin G Subclass Antibody Cocktail for Diagnosis of Type 1 Autoimmune Pancreatitis INTERNATIONAL JOURNAL OF SURGICAL PATHOLOGY,28(8):844-849 2020(Dec.) Author:Nakata, Rie; Uehara, Takeshi; Iwaya, Mai; Asaka, Shiho; Kobayashi, Shota; Sugano, Mitsutoshi; Higuchi, Kayoko; Kusama, Yukiko; Nakazawa, Koh; Nakaguro, Masato; Kobayashi, Mikiko; Tateishi, Ayako; Makino, Mutsuki; Kawaguchi, Kenji; Maejima, Toshitaka; Ishii, Keiko; Sano, Kenji; Shimojo, Hisashi; Hori, Atsushi; Otsuki, Toshiaki; Hamano, Hideaki; Kawa, Shigeyuki; Ota, Hiroyoshi; Keywords:IgG4-related disease; type 1 autoimmune pancreatitis; IgG; antibody cocktail containing mixed IgG1; IgG2; IgG3; and IgG4;
Correlation of clinicopathological features and LGR5 expression in colon adenocarcinoma ANNALS OF DIAGNOSTIC PATHOLOGY,48 2020(Oct.) Author:Sato, Koichi; Uehara, Takeshi; Iwaya, Mai; Nakajima, Tomoyuki; Miyagawa, Yusuke; Ota, Hiroyoshi; Tanaka, Eiji; Keywords:Leucine-rich repeat-containing G-protein-coupled receptor 5; Tumor budding; RNA in situ hybridization; Colon adenocarcinoma;
Correlation of Clinicopathological Features and LGR5 Expression in Triple-Negative Breast Cancer ANNALS OF DIAGNOSTIC PATHOLOGY,46 2020(Jun.) Author:Ogasawara, Souya; Uehara, Takeshi; Nakajima, Tomoyuki; Iwaya, Mai; Maeno, Kazuma; Tsuchiya, Shinichi; Ota, Hiroyoshi; Ito, Ken-ichi;
Characterization of LGR5 Expression in Tumor Budding of Colorectal Carcinoma with PD-L1 Expression MODERN PATHOLOGY,33(SUPPL 2):763-763 2020(Mar.) Author:Sato, Koichi; Uehara, Takeshi; Nakajima, Tomoyuki; Iwaya, Mai; Ota, Hiroyoshi;
Characterization of LGR5 Expression in Tumor Budding of Colorectal Carcinoma with PD-L1 Expression LABORATORY INVESTIGATION,100(SUPPL 1):763-763 2020(Mar.) Author:Sato, Koichi; Uehara, Takeshi; Nakajima, Tomoyuki; Iwaya, Mai; Ota, Hiroyoshi;
Characterization of LGR5 expression in poorly differentiated colorectal carcinoma with mismatch repair protein deficiency BMC CANCER,20(1) 2020 Author:Nakajima, Tomoyuki; Uehara, Takeshi; Iwaya, Mai; Kobayashi, Yukihiro; Maruyama, Yasuhiro; Ota, Hiroyoshi;
Immunostaining With Immunoglobulin G Subclass Antibody Cocktail for Diagnosis of Type 1 Autoimmune Pancreatitis INTERNATIONAL JOURNAL OF SURGICAL PATHOLOGY 2020 Author:Nakata, Rie; Uehara, Takeshi; Iwaya, Mai; Asaka, Shiho; Kobayashi, Shota; Sugano, Mitsutoshi; Higuchi, Kayoko; Kusama, Yukiko; Nakazawa, Koh; Nakaguro, Masato; Kobayashi, Mikiko; Tateishi, Ayako; Makino, Mutsuki; Kawaguchi, Kenji; Maejima, Toshitaka; Ishii, Keiko; Sano, Kenji; Shimojo, Hisashi; Hori, Atsushi; Otsuki, Toshiaki; Hamano, Hideaki; Kawa, Shigeyuki; Ota, Hiroyoshi;
Pedunculated signet ring cell carcinoma of the stomach mimicking a hyperplastic polyp GASTROINTESTINAL ENDOSCOPY,90(5):848-849 2019(Nov.) Author:Mochizuki, Yuichiro; Iwaya, Yugo; Iwaya, Mai; Hirota, Yuko; Inoue, Haruhiro;
Correlation of clinicopathological features and LGR5 expression in colon adenocarcinoma ANNALS OF DIAGNOSTIC PATHOLOGY,40:161-165 2019(Jun.) Author:Sato, Koichi; Uehara, Takeshi; Iwaya, Mai; Nakajima, Tomoyuki; Miyagawa, Yusuke; Suga, Tomoaki; Ota, Hiroyoshi; Tanaka, Eiji;
Colitis-associated colorectal adenocarcinomas are frequently associated with non-intestinal mucin profiles and loss of SATB2 expression MODERN PATHOLOGY,32(6):884-892 2019(Jun.) Author:Iwaya, Mai; Ota, Hiroyoshi; Tateishi, Yoko; Nakajima, Tomoyuki; Riddell, Robert; Conner, James R.;
A Comparative Immunohistochemical Study of Anal Canal Epithelium in Humans and Swine, Focusing on the Anal Transitional Zone Epithelium and the Anal Glands. Anat Rec (Hoboken).,301(5):796-805 2018(May) Author:Muranaka F, Nakajima T, Iwaya M, Ishii K, Higuchi K, Ogiwara N, Miyagawa S, Ota H.
Distribution of Lgr5-positive cancer cells in intramucosal gastric signet-ring cell carcinoma. Pathol Int,66(9):518-23 2016(Sep.) Author:Nakajima T, Uehara T, Maruyama Y, Iwaya M, Kobayashi Y, Ota H.
A case of simultaneous esophageal squamous cell carcinoma and Barrett's adenocarcinoma. Clin J Gastroenterol,9(4):222-7 2016(Aug.) Author:Yamazaki T, Iwaya Y, Iwaya M, Watanabe T, Seki A, Ochi Y, Hara E, Sekiguchi T, Hosaka N, Arakura N, Tanaka E, Hasebe O.
Insulin-Like Growth Factor II mRNA-Binding Protein 3 (IMP3) as a Useful Immunohistochemical Marker for the Diagnosis of Adenocarcinoma of Small Intestine. Acta Histochem Cytochem,48(6):193-204 2015(Dec.) Author:Daikuhara S, Uehara T, Higuchi K, Hosaka N, Iwaya M, Maruyama Y, Matsuda K, Arakura N, Tanaka E, Ota H.
Principal cells in gastric neoplasia of fundic gland (chief cell predominant) type show characteristics of immature chief cells PATHOLOGY INTERNATIONAL,65(4):202-204 2015(Apr.) Author:Ota, Hiroyoshi; Yamaguchi, Dai; Iwaya, Mai; Kobayashi, Mikiko; Tateiwa, Nobuyuki; Iwaya, Yugo; Momose, Masanobu; Uehara, Takeshi;
Principal cells in gastric neoplasia of fundic gland (chief cell predominant) type show characteristics of immature chief cells. Pathol Int,65(4):202-4 2015(Apr.) Author:Ota H, Yamaguchi D, Iwaya M, Kobayashi M, Tateiwa N, Iwaya Y, Momose M, Uehara T.
Successful living donor liver transplantation for acute liver failure after acetylsalicylic acid overdose. Clin J Gastroenterol,8(2):97-102 2015(Apr.) Author:Shirota T, Ikegami T, Sugiyama S, Kubota K, Shimizu A, Ohno Y, Mita A, Urata K, Nakazawa Y, Kobayashi A, Iwaya M, Miyagawa S.
Insulin-Like Growth Factor II mRNA-Binding Protein 3 (IMP3) as a Useful Immunohistochemical Marker for the Diagnosis of Adenocarcinoma of Small Intestine ACTA HISTOCHEMICA ET CYTOCHEMICA,48(6):193-204 2015 Author:Daikuhara, Seiichi; Uehara, Takeshi; Higuchi, Kayoko; Hosaka, Noriko; Iwaya, Mai; Maruyama, Yasuhiro; Matsuda, Kazuyuki; Arakura, Norikazu; Tanaka, Eiji; Ota, Hiroyoshi;
Eosinophilic gastroenteritis complicated with Helicobacter pylori infection unresponsive to eradication therapy Intern Med,53:2061-2065 2014 Author:Nakamura A, Iwaya Y, Iwaya M, Okamura T, Kobayashi S, Daikuhara S, Nozawa Y, Fukuzawa S, Nakamura S, Okuhara S, Yamada S, Yokosawa S, Suga T, Arakura N, Tanaka E
A Case of Primary Signet-Ring Cell/Histiocytoid Carcinoma of the Eyelid: Immunohistochemical Comparison With the Normal Sweat Gland and Review of the Literature AMERICAN JOURNAL OF DERMATOPATHOLOGY,34(8):E139-E145 2012(Dec.) Author:Iwaya, Mai; Uehara, Takeshi; Yoshizawa, Akihiko; Kobayashi, Yukihiro; Momose, Masanobu; Honda, Takayuki; Ota, Hiroyoshi;
IgG4-Related Airway Involvement Which Developed in a Patient Receiving Corticosteroid Therapy for Autoimmune Pancreatitis INTERNAL MEDICINE,50(24):3023-3026 2011 Author:Yamamoto, Hiroshi; Yasuo, Masanori; Nomura, Yayoi; Agatsuma, Toshihiko; Ushiki, Atsuhito; Yokoyama, Toshiki; Urushihata, Kazuhisa; Hanaoka, Masayuki; Koizumi, Tomonobu; Iwaya, Mai; Yoshizawa, Akihiko; Kawakami, Satoshi; Hamano, Hideaki; Kawa, Shigeyuki; Kubo, Keishi;
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