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岩谷 舞  イワヤ マイ

教員組織学術研究院(医学系(附属病院)) 電話番号
教育組織医学部附属病院 臨床検査部FAX番号
職名講師メールアドレス
住所〒390-8621 長野県松本市旭3-1-1ホームページURL

プロフィール

研究分野
消化管病理
キーワード:消化管病理 , 炎症性腸疾患
所属学会
所属学会
United States and Canadian Academy of Pathology
日本臨床検査医学会
日本臨床細胞学会
日本病理学会
学歴
出身学校・専攻等(大学院を除く)
2005 , 信州大学

取得学位
医学博士 , 信州大学
研究職歴等
留学歴
2016- , トロント大学
2016-2018 , トロント大学

研究活動業績

研究業績(著書・
発表論文等)
論文
Colitis-associated colorectal adenocarcinomas frequently express claudin 18 isoform 2: implications for claudin 18.2 monoclonal antibody therapy
HISTOPATHOLOGY,79(2):227-237 2021(Aug.)
Author:Iwaya, Mai; Hayashi, Hiroyuki; Nakajima, Tomoyuki; Matsuda, Kazuyuki; Kinugawa, Yasuhiro; Tobe, Yosuke; Tateishi, Yoko; Iwaya, Yugo; Uehara, Takeshi; Ota, Hiroyoshi;
Keywords:claudin‐ 18; colorectal adenocarcinoma; HER2; inflammatory bowel disease; zolbetuximab;


Inverse correlation between PD-L1 expression and LGR5 expression in tumor budding of stage II/III colorectal cancer
ANNALS OF DIAGNOSTIC PATHOLOGY,52 2021(Jun.)
Author:Sato, Koichi; Uehara, Takeshi; Nakajima, Tomoyuki; Iwaya, Mai; Miyagawa, Yusuke; Watanabe, Takayuki; Ota, Hiroyoshi;
Keywords:Tumor budding; Leucine-rich repeat-containing G-protein-coupled receptor 5; PD-L1; RNA in situ hybridization; Colorectal adenocarcinoma;


Direct Intraesophageal Growth from Metastatic Mediastinal Lymphadenopathy in Thymic Carcinoma
INTERNAL MEDICINE,60(6):923-926 2021
Author:Kanazawa, Hiroki; Sasaki, Nobukazu; Kobayashi, Takashi; Fukushima, Toshirou; Kanda, Shintaro; Koizumi, Tomonobu; Iwaya, Mai;
Keywords:mediastinal tumor; subcarinal lymph node; ADOC chemotherapy; esophagus;


Most colitis associated carcinomas lack expression of LGR5: a preliminary study with implications for unique pathways of carcinogenesis compared to sporadic colorectal carcinoma
BMC CANCER,21(1) 2021
Author:Iwaya, Mai; Ota, Hiroyoshi; Nakajima, Tomoyuki; Uehara, Takeshi; Riddell, Robert; Conner, James;
Keywords:Inflammatory bowel disease; Ulcerative colitis; Crohn's disease; Colitis associated colorectal carcinoma; LGR5;


LGR5 expression is associated with prognosis in poorly differentiated gastric adenocarcinoma
BMC CANCER,21(1) 2021
Author:Ehara, Takehito; Uehara, Takeshi; Nakajima, Tomoyuki; Kinugawa, Yasuhiro; Kobayashi, Shota; Iwaya, Mai; Ota, Hiroyoshi; Soejima, Yuji;
Keywords:Leucine-rich repeat-containing G-protein-coupled receptor 5; Poorly differentiated gastric adenocarcinoma; RNA in situ hybridization;


LGR5-Expressing Cells in the Healing Process of Post-ESD Ulcers in Gastric Corpus
DIGESTIVE DISEASES AND SCIENCES 2021
Author:Tobe, Yosuke; Uehara, Takeshi; Nakajima, Tomoyuki; Iwaya, Mai; Kobayashi, Yukihiro; Kinugawa, Yasuhiro; Kuraishi, Yasuhiro; Ota, Hiroyoshi;
Keywords:LGR5; RNA in situ hybridization; Pseudopyloric metaplasia; Chief cell;


IL-6 expression helps distinguish Castleman's disease from IgG4-related disease in the lung
BMC PULMONARY MEDICINE,21(1) 2021
Author:Kinugawa, Yasuhiro; Uehara, Takeshi; Iwaya, Mai; Asaka, Shiho; Kobayashi, Shota; Nakajima, Tomoyuki; Komatsu, Masamichi; Yasuo, Masanori; Yamamoto, Hiroshi; Ota, Hiroyoshi;
Keywords:Multicentric Castleman's disease; IgG4-related disease; IgG4-related lung disease; Interleukin-6; RNAscope; RNA in situ hybridization;


Impact of DNA double-strand breaks on pancreaticobiliary maljunction carcinogenesis
DIAGNOSTIC PATHOLOGY,16(1) 2021
Author:Kuraishi, Yasuhiro; Uehara, Takeshi; Muraki, Takashi; Iwaya, Mai; Kinugawa, Yasuhiro; Nakajima, Tomoyuki; Watanabe, Takayuki; Miyagawa, Yusuke; Umemura, Takeji;
Keywords:Carcinogenesis; DNA double-strand break; Gallbladder; Pancreaticobiliary maljunction; gamma-H2AX;


Clinicopathological features of nodular gastritis in three classes of age
HELICOBACTER 2021
Author:Kako, Satoko; Iwaya, Yugo; Nagaya, Tadanobu; Hara, Daichi; Okamura, Takuma; Iwaya, Mai; Kurasawa, Shingo; Kato, Sawako; Nakayama, Yoshiko; Akamatsu, Taiji; Umemura, Takeji;
Keywords:classes of age; inflammation; nodular gastritis; pangastritis; updated Sydney System score;


Correlation of clinicopathological features and LGR5 expression in colon adenocarcinoma
ANNALS OF DIAGNOSTIC PATHOLOGY,48 2020(Oct.)
Author:Sato, Koichi; Uehara, Takeshi; Iwaya, Mai; Nakajima, Tomoyuki; Miyagawa, Yusuke; Ota, Hiroyoshi; Tanaka, Eiji;
Keywords:Leucine-rich repeat-containing G-protein-coupled receptor 5; Tumor budding; RNA in situ hybridization; Colon adenocarcinoma;


Correlation of Clinicopathological Features and LGR5 Expression in Triple-Negative Breast Cancer
ANNALS OF DIAGNOSTIC PATHOLOGY,46 2020(Jun.)
Author:Ogasawara, Souya; Uehara, Takeshi; Nakajima, Tomoyuki; Iwaya, Mai; Maeno, Kazuma; Tsuchiya, Shinichi; Ota, Hiroyoshi; Ito, Ken-ichi;


Characterization of LGR5 Expression in Tumor Budding of Colorectal Carcinoma with PD-L1 Expression
MODERN PATHOLOGY,33(SUPPL 2):763-763 2020(Mar.)
Author:Sato, Koichi; Uehara, Takeshi; Nakajima, Tomoyuki; Iwaya, Mai; Ota, Hiroyoshi;


Characterization of LGR5 Expression in Tumor Budding of Colorectal Carcinoma with PD-L1 Expression
LABORATORY INVESTIGATION,100(SUPPL 1):763-763 2020(Mar.)
Author:Sato, Koichi; Uehara, Takeshi; Nakajima, Tomoyuki; Iwaya, Mai; Ota, Hiroyoshi;


Characterization of LGR5 expression in poorly differentiated colorectal carcinoma with mismatch repair protein deficiency
BMC CANCER,20(1) 2020
Author:Nakajima, Tomoyuki; Uehara, Takeshi; Iwaya, Mai; Kobayashi, Yukihiro; Maruyama, Yasuhiro; Ota, Hiroyoshi;


Immunostaining With Immunoglobulin G Subclass Antibody Cocktail for Diagnosis of Type 1 Autoimmune Pancreatitis
INTERNATIONAL JOURNAL OF SURGICAL PATHOLOGY 2020
Author:Nakata, Rie; Uehara, Takeshi; Iwaya, Mai; Asaka, Shiho; Kobayashi, Shota; Sugano, Mitsutoshi; Higuchi, Kayoko; Kusama, Yukiko; Nakazawa, Koh; Nakaguro, Masato; Kobayashi, Mikiko; Tateishi, Ayako; Makino, Mutsuki; Kawaguchi, Kenji; Maejima, Toshitaka; Ishii, Keiko; Sano, Kenji; Shimojo, Hisashi; Hori, Atsushi; Otsuki, Toshiaki; Hamano, Hideaki; Kawa, Shigeyuki; Ota, Hiroyoshi;


Pedunculated signet ring cell carcinoma of the stomach mimicking a hyperplastic polyp
GASTROINTESTINAL ENDOSCOPY,90(5):848-849 2019(Nov.)
Author:Mochizuki, Yuichiro; Iwaya, Yugo; Iwaya, Mai; Hirota, Yuko; Inoue, Haruhiro;


Correlation of clinicopathological features and LGR5 expression in colon adenocarcinoma
ANNALS OF DIAGNOSTIC PATHOLOGY,40:161-165 2019(Jun.)
Author:Sato, Koichi; Uehara, Takeshi; Iwaya, Mai; Nakajima, Tomoyuki; Miyagawa, Yusuke; Suga, Tomoaki; Ota, Hiroyoshi; Tanaka, Eiji;


Colitis-associated colorectal adenocarcinomas are frequently associated with non-intestinal mucin profiles and loss of SATB2 expression
MODERN PATHOLOGY,32(6):884-892 2019(Jun.)
Author:Iwaya, Mai; Ota, Hiroyoshi; Tateishi, Yoko; Nakajima, Tomoyuki; Riddell, Robert; Conner, James R.;


A Comparative Immunohistochemical Study of Anal Canal Epithelium in Humans and Swine, Focusing on the Anal Transitional Zone Epithelium and the Anal Glands.
Anat Rec (Hoboken).,301(5):796-805 2018(May)
Author:Muranaka F, Nakajima T, Iwaya M, Ishii K, Higuchi K, Ogiwara N, Miyagawa S, Ota H.


Distribution of Lgr5-positive cancer cells in intramucosal gastric signet-ring cell carcinoma.
Pathol Int,66(9):518-23 2016(Sep.)
Author:Nakajima T, Uehara T, Maruyama Y, Iwaya M, Kobayashi Y, Ota H.


A case of simultaneous esophageal squamous cell carcinoma and Barrett's adenocarcinoma.
Clin J Gastroenterol,9(4):222-7 2016(Aug.)
Author:Yamazaki T, Iwaya Y, Iwaya M, Watanabe T, Seki A, Ochi Y, Hara E, Sekiguchi T, Hosaka N, Arakura N, Tanaka E, Hasebe O.


Insulin-Like Growth Factor II mRNA-Binding Protein 3 (IMP3) as a Useful Immunohistochemical Marker for the Diagnosis of Adenocarcinoma of Small Intestine.
Acta Histochem Cytochem,48(6):193-204 2015(Dec.)
Author:Daikuhara S, Uehara T, Higuchi K, Hosaka N, Iwaya M, Maruyama Y, Matsuda K, Arakura N, Tanaka E, Ota H.


Principal cells in gastric neoplasia of fundic gland (chief cell predominant) type show characteristics of immature chief cells
PATHOLOGY INTERNATIONAL,65(4):202-204 2015(Apr.)
Author:Ota, Hiroyoshi; Yamaguchi, Dai; Iwaya, Mai; Kobayashi, Mikiko; Tateiwa, Nobuyuki; Iwaya, Yugo; Momose, Masanobu; Uehara, Takeshi;


Principal cells in gastric neoplasia of fundic gland (chief cell predominant) type show characteristics of immature chief cells.
Pathol Int,65(4):202-4 2015(Apr.)
Author:Ota H, Yamaguchi D, Iwaya M, Kobayashi M, Tateiwa N, Iwaya Y, Momose M, Uehara T.


Successful living donor liver transplantation for acute liver failure after acetylsalicylic acid overdose.
Clin J Gastroenterol,8(2):97-102 2015(Apr.)
Author:Shirota T, Ikegami T, Sugiyama S, Kubota K, Shimizu A, Ohno Y, Mita A, Urata K, Nakazawa Y, Kobayashi A, Iwaya M, Miyagawa S.


Helicobacter pylori-negative Differentiated Adenocarcinoma of the Stomach
INTERNAL MEDICINE,54(22):2857-2862 2015
Author:Nagaya, Tadanobu; Tanaka, Naoki; Iwaya, Yugo; Jimbo, Yoko; Tatai, Toshiharu; Ito, Tetsuya; Seki, Ayako; Suzawa, Kenichi; Ochi, Yasuhide; Hara, Etsuo; Takata, Manabu; Otsuki, Toshiaki; Iwaya, Mai; Hosaka, Noriko; Arakura, Norikazu; Tanaka, Eiji; Hasebe, Osamu;


Insulin-Like Growth Factor II mRNA-Binding Protein 3 (IMP3) as a Useful Immunohistochemical Marker for the Diagnosis of Adenocarcinoma of Small Intestine
ACTA HISTOCHEMICA ET CYTOCHEMICA,48(6):193-204 2015
Author:Daikuhara, Seiichi; Uehara, Takeshi; Higuchi, Kayoko; Hosaka, Noriko; Iwaya, Mai; Maruyama, Yasuhiro; Matsuda, Kazuyuki; Arakura, Norikazu; Tanaka, Eiji; Ota, Hiroyoshi;


Eosinophilic Gastroenteritis Complicated with Helicobacter pylori Infection Unresponsive to Eradication Therapy
INTERNAL MEDICINE,53(18):2061-2065 2014
Author:Nakamura, Akira; Iwaya, Yugo; Iwaya, Mai; Okamura, Takuma; Kobayashi, Satoshi; Daikuhara, Seiichi; Nozawa, Yuichi; Fukuzawa, Shinya; Nakamura, Shinichiro; Okuhara, Sadahisa; Yamada, Shigenori; Yokosawa, Shuichi; Suga, Tomoaki; Arakura, Norikazu; Tanaka, Eiji;


Eosinophilic gastroenteritis complicated with Helicobacter pylori infection unresponsive to eradication therapy
Intern Med,53:2061-2065 2014
Author:Nakamura A, Iwaya Y, Iwaya M, Okamura T, Kobayashi S, Daikuhara S, Nozawa Y, Fukuzawa S, Nakamura S, Okuhara S, Yamada S, Yokosawa S, Suga T, Arakura N, Tanaka E


A Case of Primary Signet-Ring Cell/Histiocytoid Carcinoma of the Eyelid: Immunohistochemical Comparison With the Normal Sweat Gland and Review of the Literature
AMERICAN JOURNAL OF DERMATOPATHOLOGY,34(8):E139-E145 2012(Dec.)
Author:Iwaya, Mai; Uehara, Takeshi; Yoshizawa, Akihiko; Kobayashi, Yukihiro; Momose, Masanobu; Honda, Takayuki; Ota, Hiroyoshi;


IgG4-Related Airway Involvement Which Developed in a Patient Receiving Corticosteroid Therapy for Autoimmune Pancreatitis
INTERNAL MEDICINE,50(24):3023-3026 2011
Author:Yamamoto, Hiroshi; Yasuo, Masanori; Nomura, Yayoi; Agatsuma, Toshihiko; Ushiki, Atsuhito; Yokoyama, Toshiki; Urushihata, Kazuhisa; Hanaoka, Masayuki; Koizumi, Tomonobu; Iwaya, Mai; Yoshizawa, Akihiko; Kawakami, Satoshi; Hamano, Hideaki; Kawa, Shigeyuki; Kubo, Keishi;

研究費
受託研究
2018 - 2020 , 病理診断支援のための人工知能(病理診断支援AI)開発と統合的「AI医療画像知」の創出

科学研究費補助金(研究代表者)
2020 - , IBD関連腫瘍におけるSATB2発現に関与する分子生物学的メカニズムの探索 , 若手研究