博士(工学), 北九州市立大学

ナノテク・材料, ナノバイオサイエンス

ナノテク・材料, 高分子材料

ナノテク・材料, ナノマイクロシステム

Ion valency–driven control of network architecture and tissue-level drug transport in protein-derived hydrogels
Han Jae Choi; Kayeong Go; Tomoki Nishimura; Azeem Ullah; Gopiraman Mayakrishnan; Ick Soo Kim; Ji Ha Lee
International Journal of Biological Macromolecules, 153100-153100, 2026年06月

Multi-functional photonic crystals of modular nanosheets
Seiya Yui; Takumi Mihara; Tomoki Nishimura; Yasuo Ebina; Takayoshi Sasaki; Koki Sano
Nature Communications, 2026年05月

Highly Viscoelastic Supramolecular Polymers of Pt(II) Complexes with Exceptional Mechanical Reinforcement
Sehee Kim; Minju Nam; Minjoo Kim; Tomoki Nishimura; Ji Ha Lee; Sung Ho Jung; Jong Hwa Jung
Chemistry of Materials, 2026年05月

High Drug Encapsulation Capacity in Cyclodextrin-Based Nanoparticles: Characterization and In Vivo Antitumor Efficacy in Tumor-Bearing Mice
Tomoki Kosugi; Mina Sakuragi; Madoka Toya; Tomoki Nishimura; Taiki Saito; Reina Kobayashi; Liliana de Campo; Kazuo Sakurai; Riku Kawasaki; Noriko Miyamoto
ACS Bio & Med Chem Au, 6(2), 168-177, 2026年04月

Engineering Cylindrical Macromolecular Assemblies With Zwitterionic Amino Acids for Concurrent Prolonged Circulation and Tumor Targeting
Jokichi Fukushima; Noriko Miyamoto; Shota Fujii; Tomoki Nishimura
Small, 2026年03月

Substrate-selective nanofactories constructed from enzyme-loaded thermoresponsive peptoid-b-oligosaccharide vesicles
Yota Okuno; Tomoki Nishimura; Yasuhiko Iwasaki; Yoshihiro Sasaki; Kazunari Akiyoshi
POLYMER JOURNAL, 2025年11月

Poly(2‐Propyl‐2‐Oxazoline)‐Induced Lipid Nanotube Formation in Phospholipid Multilayers
Ryosuke Mizuta; Tatsuhiko Murata; Mitsuru Ando; Tomoki Nishimura; Shin‐ichi Sawada; Kazunari Akiyoshi; Yoshihiro Sasaki
Macromolecular Rapid Communications, 2025年11月

Tunable pH-Responsive Release Kinetics of Doxorubicin from Iron Oxide-Loaded Cellulose Acetate Nanofibers for Localized Drug Delivery
Dayae Kang; Ji Ha Lee; Azeem Ullah; Gopiraman Mayakrishnan; Chieri Inada; Tomoki Nishimura; Jungsoon Lee; Ick Soo Kim
ACS APPLIED POLYMER MATERIALS, 7(18), 12732-12742, 2025年09月

Kinetically controlled crystallization-driven self-assembly of peptoid block copolymers
Renya Fukuda; Yota Okuno; Tomoki Nishimura; Yasuhiko Iwasaki
MRS COMMUNICATIONS, 2025年09月, 査読有り, 招待有り

Multistage Activation Barriers in the Chiral Metallosupramolecular Polymerization of Alkynylplatinum(II) Complexes
Kayeong Go; Tomoki Nishimura; Sung Ho Jung; Jong Hwa Jung
Small, 2025年05月

Dopasomes: dopamine-mediated cross-linked lipid vesicles
Keita Yamana; Kouki Fujihara; Miu Maeda; Tomoki Nishimura; Riku Kawasaki; Atsushi Ikeda
Journal of Materials Chemistry B, 13(40), 12890-12894, 2025年

Self-assembly of thioether-based diblock copolymers: a comparative study of linear and bottlebrush architectures
Shin Takano; Tomoki Nishimura; Yen Theng Cheng; Markus Müllner
Polymer Chemistry, 16(19), 2244-2253, 2025年

Platinum catalyst-functionalized cylindrical graft copolymer micelles for dual catalytic and cytotoxic activity
Kyosuke Seryu; Chieri Inada; Tomoki Nishimura
Materials Advances, 6(17), 6001-6007, 2025年

Self-assembled block copolymer domains as macromolecular ion transport systems in biological membranes
Shunji Kosaka; Jokichi Fukushima; Nanami Takeuchi; Noriko Miyamoto; Liliana de Campo; Ryuji Kawano; Tomoki Nishimura
Chemical Science, 2025年

Manipulation of Macrophage Uptake by Controlling the Aspect Ratio of Graft Copolymer Micelles.
Yusuke Sakamoto; Shota Fujii; Shin Takano; Jokichi Fukushima; Mitsuru Ando; Noriyuki Kodera; Tomoki Nishimura
Nano letters, 2024年04月

A magnetically responsive photonic crystal of graphene oxide nanosheets
Daisuke Ogawa; Tomoki Nishimura; Yuta Nishina; Koki Sano
Nanoscale, 2024年

Macromolecular architectural effects on solution self-assembly of amphiphilic AB-type block copolymers
Naoki Ozawa; Tomoki Nishimura
Polymer Chemistry, 15(5), 349-370, 2024年, 査読有り

HER-2-targeted Boron Neutron Capture Therapy with Carborane-integrated Immunoliposomes Prepared via an Exchanging Reaction.
Riku Kawasaki; Ayano Oshige; Keita Yamana; Hidetoshi Hirano; Kotaro Nishimura; Yamato Miura; Ryuji Yorioka; Yu Sanada; Kaori Bando; Anri Tabata; Kazuma Yasuhara; Yusuke Miyazaki; Wataru Shinoda; Tomoki Nishimura; Hideki Azuma; Takushi Takata; Yoshinori Sakurai; Hiroki Tanaka; Minoru Suzuki; Takeshi Nagasaki; Atsushi Ikeda
Chemistry (Weinheim an der Bergstrasse, Germany), e202302486, 2023年10月, 査読有り

Exploring the effects of glyco-copolymer architectures on the solution self-assembly of amphiphilic thermoresponsive linear, star, and cyclic polymers
Naoki Ozawa; Ji Ha Lee; Isamu Akiba; Tomoki Nishimura
Polymer Chemistry, 14(33), 3834-3842, 2023年08月

Countercation Engineering of Graphene-Oxide Nanosheets for Imparting a Thermoresponsive Ability
Shoma Kondo; Tomoki Nishimura; Yuta Nishina; Koki Sano
ACS Applied Materials & Interfaces, 15, 37837-37844, 2023年07月, 査読有り

Development of a Water‐Dispersible Supramolecular Complex of Polyphenol with Polypeptides for Attenuation of the Allergic Response using a Mechanochemical Strategy
Riku Kawasaki; Shogo Kawamura; Tomoki Kodama; Keita Yamana; Akira Maeda; Dilimulati Yimiti; Shigeru Miyaki; Shodai Hino; Naoki Ozawa; Tomoki Nishimura; Seiji Kawamoto; Atsushi Ikeda
Macromolecular Bioscience, 2200462-2200462, 2023年01月

Bilayer-domain formation of thermoresponsive amphiphilic block copolymers in hybrid liposomes for synthetic molecular channels
Naoki Ozawa; Shunji Kosaka; Shota Fujii; Tomoki Nishimura
Polymer Chemistry, 14(18), 2198-2204, 2023年, 査読有り
最終著者, 責任著者

Fluorescence sensor using porous host molecules deposited on filter paper with vapochromic and mechanochromic properties
Sota Umezane; Satoshi Fukutomi; Toshikazu Ono; Yoshio Hisaeda; Tomoki Nishimura; Riku Kawasaki; Atsushi Ikeda
New Journal of Chemistry, 2023年

Circularly Polarized Luminescence Active Supramolecular Nanotubes Based on Pt Complexes That Undergo Dynamic Morphological Transformation and Helicity Inversion
Seok Gyu Kang; Ka Young Kim; Yumi Cho; Dong Yeun Jeong; Ji Ha Lee; Tomoki Nishimura; Shim Sung Lee; Sang Kyu Kwak; Youngmin You; Jong Hwa Jung
Angewandte Chemie International Edition, 61(38), 2022年09月

Supramolecular Shear-Thinning Glycopeptide Hydrogels for Injectable Enzyme Prodrug Therapy Applications
Yusuke Sakamoto; Fumi Suehiro; Isamu Akiba; Tomoki Nishimura
Langmuir, 38(18), 5883-5890, 2022年05月, 査読有り
最終著者, 責任著者

Theranostic Agent Combining Fullerene Nanocrystals and Gold Nanoparticles for Photoacoustic Imaging and Photothermal Therapy
Riku Kawasaki; Kosuke Kondo; Risako Miura; Keita Yamana; Hinata Isozaki; Risako Shimada; Shogo Kawamura; Hidetoshi Hirano; Tomoki Nishimura; Naoki Tarutani; Kiyofumi Katagiri; Alexandra Stubelius; Shin-ichi Sawada; Yoshihiro Sasaki; Kazunari Akiyoshi; Atsushi Ikeda
International Journal of Molecular Sciences, 23(9), 4686-4686, 2022年04月, 査読有り

A solid-in-oil-in-water emulsion: An adjuvant-based immune-carrier enhances vaccine effect
Yoshiro Tahara; Riko Mizuno; Tomoki Nishimura; Sada-atsu Mukai; Rie Wakabayashi; Noriho Kamiya; Kazunari Akiyoshi; Masahiro Goto
Biomaterials, 282, 121385-121385, 2022年03月, 査読有り

Recent advances in the self-assembly of sparsely grafted amphiphilic copolymers in aqueous solution
Yusuke Sakamoto; Tomoki Nishimura
Polymer Chemistry, 13(46), 6343-6360, 2022年, 査読有り

Glycopeptoid Nanospheres: Glycosylation-Induced Coacervation of Poly(sarcosine)
Yota Okuno; Tomoki Nishimura; Yoshihiro Sasaki; Kazunari Akiyoshi
Nanoscale Advances, 2022年

Bioorthogonal micellar nanoreactors for prodrug cancer therapy using an inverse-electron-demand Diels–Alder reaction
Fumi Suehiro; Shota Fujii; Tomoki Nishimura
Chemical Communications, 58(50), 7026-7029, 2022年, 査読有り
最終著者, 責任著者

Single-component nanodiscs via the thermal folding of amphiphilic graft copolymers with the adjusted flexibility of the main chain
Tomoki Nishimura; Yusuke Hatatani; Mitsuru Ando; Yoshihiro Sasaki; Kazunari Akiyoshi
Chemical Science, 13(18), 5243-5251, 2022年, 査読有り
筆頭著者, 責任著者

Preparation of Aqueous Solutions with Information on Solids (ASIS) of a Mechanochromic Luminescent Tetraphenylethylene Derivative by Complexation with Polysaccharides
Riku Omokawa; Riku Kawasaki; Kouta Sugikawa; Tomoki Nishimura; Toshimi Nakaya; Atsushi Ikeda
ACS APPLIED POLYMER MATERIALS, 3(8), 3708-3713, 2021年08月

Manipulating the Morphology of Amphiphilic Graft-Copolymer Assemblies by Adjusting the Flexibility of the Main Chain
Tomoki Nishimura; Shota Fujii; Kazuo Sakurai; Yoshihiro Sasaki; Kazunari Akiyoshi
Macromolecules, 54(14), 7003-7009, 2021年07月

Thermoresponsive Carbohydrate-b-Polypeptoid Polymer Vesicles with Selective Solute Permeability and Permeable Factors for Solutes
Yota Okuno; Tomoki Nishimura; Yoshihiro Sasaki; Kazunari Akiyoshi
BIOMACROMOLECULES, 22(7), 3099-3106, 2021年07月

Thermoresponsive glycopolymer vesicles: in situ observation of morphological changes and triggered cargo release
Tomoki Nishimura; Yoshihiro Sasaki; Kazunari Akiyoshi
Polymer Journal, 53(11), 1251-1258, 2021年04月, 査読有り

Magnetically Navigated Protein Transduction In Vivo using Iron Oxide-Nanogel Chaperone Hybrid
Riku Kawasaki; Yoshihiro Sasaki; Tomoki Nishimura; Kiyofumi Katagiri; Kei ichi Morita; Yurina Sekine; Shin ichi Sawada; Sada atsu Mukai; Kazunari Akiyoshi
Advanced Healthcare Materials, 10(9), 2021年

Biocatalytic Hybrid Films Self-Assembled from Carbohydrate Block Copolymers and Polysaccharides for Enzyme Prodrug Therapy
Tomoki Nishimura; Yusuke Nakamura; Naoya Kinoshita; Katsuhiro Yamamoto; Yoshihiro Sasaki; Kazunari Akiyoshi
ACS Applied Bio Materials, 3(12), 8865-8871, 2020年12月, 査読有り
筆頭著者, 責任著者

Determining the Hydration in the Hydrophobic Layer of Permeable Polymer Vesicles by Neutron Scattering
Tomoki Nishimura; Liliana de Campo; Hiroki Iwase; Kazunari Akiyoshi
Macromolecules, 2020年08月, 査読有り
筆頭著者, 責任著者

Thermoresponsive Polysaccharide Graft Polymer Vesicles with Tunable Size and Structural Memory
Tomoki Nishimura; Shen Shishi; Yoshihiro Sasaki; Kazunari Akiyoshi
Journal of the American Chemical Society, 142(27), 11784-11790, 2020年07月, 査読有り
筆頭著者, 責任著者

Artificial Molecular Chaperone Systems for Proteins, Nucleic Acids, and Synthetic Molecules
Tomoki Nishimura; Kazunari Akiyoshi
Bioconjugate Chemistry, 31(5), 1259-1267, 2020年05月, 査読有り
筆頭著者

Substrate-Sorting Nanoreactors Based on Permeable Peptide Polymer Vesicles and Hybrid Liposomes with Synthetic Macromolecular Channels
Tomoki Nishimura; Shin Hirose; Yoshihiro Sasaki; Kazunari Akiyoshi
Journal of the American Chemical Society, 142(1), 154-161, 2020年01月, 査読有り
筆頭著者, 責任著者

Design of glyco polymer vesicles and their function as DDS nanofactories
Tomoki Nishimura; Kazunari Akiyoshi
Drug Delivery System, 34(3), 154-162, 2019年

Synthesis and function of amphiphilic glucan dendrimers as nanocarriers for protein delivery
Shigeo Takeda; Tomoki Nishimura; Kaori Umezaki; Akiko Kubo; Michiyo Yanase; Shin-ichi Sawada; Yoshihiro Sasaki; Kazunari Akiyoshi
Biomaterials Science, 7(4), 1617-1622, 2019年, 査読有り

Intrinsically permeable polymer vesicles based on carbohydrate-conjugated poly(2-oxazoline)s synthesized using a carbohydrate-based initiator system
Tomoki Nishimura; Naoki Sumi; Yuta Koda; Yoshihiro Sasaki; Kazunari Akiyoshi
Polymer Chemistry, 10(6), 691-697, 2019年, 査読有り

Supramacromolecular injectable hydrogels by crystallization-driven self-assembly of carbohydrate-conjugated poly(2-isopropyloxazoline)s for biomedical applications
Tomoki Nishimura; Naoki Sumi; Sada-atsu Mukai; Yoshihiro Sasaki; Kazunari Akiyoshi
Journal of Materials Chemistry B, 7(41), 6362-6369, 2019年, 査読有り

Biotransporting Biocatalytic Reactors Toward Therapeutic Nanofactories
Tomoki Nishimura; Kazunari Akiyoshi
Advanced Science, 5(11), 1800801, 2018年, 査読有り

Synthesis and Characterization of Shell‐Cross‐Linked Glycopolymer Bilayer Vesicles
Tomoki Nishimura; Wei‐Lun Toh; Kazunari Akiyoshi
Macromolecular rapid communication, 39(23), 1800384, 2018年, 査読有り

Self-Assembled Polypeptide Nanogels with Enzymatically Transformable Surface as a Small Interfering RNA Delivery Platform
Tomoki Nishimura; Akina Yamada; Kaori Umezaki; Shin-ichi Sawada; Sada-atsu Mukai; Yoshihiro Sasaki; Kazunari Akiyoshi
BIOMACROMOLECULES, 18(12), 3913-3923, 2017年12月, 査読有り

Biotransporting Self-Assembled Nanofactories Using Polymer Vesicles with Molecular Permeability for Enzyme Prodrug Cancer Therapy
Tomoki Nishimura; Yoshihiro Sasaki; Kazunari Akiyoshi
ADVANCED MATERIALS, 29(36), 1702406, 2017年09月, 査読有り

Amylose engineering: phosphorylase-catalyzed polymerization of functional saccharide primers for glycobiomaterials
Tomoki Nishimura; Kazunari Akiyoshi
WILEY INTERDISCIPLINARY REVIEWS-NANOMEDICINE AND NANOBIOTECHNOLOGY, 9(2), e1423, 2017年03月, 査読有り

Self-Assembled Nanogels of Cholesterol-Bearing Hydroxypropyl Cellulose: A Thermoresponsive Building Block for Nanogel Tectonic Materials
Yoshiro Tahara; Mizuki Sakiyama; Shigeo Takeda; Tomoki Nishimura; Sada-atsu Mukai; Shin-ichi Sawada; Yoshihiro Sasaki; Kazunari Akiyoshi
LANGMUIR, 32(47), 12283-12289, 2016年11月, 査読有り

A light sensitive self-assembled nanogel as a tecton for protein patterning materials
Tomoki Nishimura; Masahiro Takara; Sada-atsu Mukai; Shin-ichi Sawada; Yoshihiro Sasaki; Kazunari Akiyoshi
CHEMICAL COMMUNICATIONS, 52(6), 1222-1225, 2016年, 査読有り

Long-Lasting and Efficient Tumor Imaging Using a High Relaxivity Polysaccharide Nanogel Magnetic Resonance Imaging Contrast Agent
Minnie Chan; Jacques Lux; Tomoki Nishimura; Kazunari Akiyoshi; Adah Almutairi
BIOMACROMOLECULES, 16(9), 2964-2971, 2015年09月, 査読有り

Glyco Star Polymers as Helical Multivalent Host and Biofunctional Nano-Platform
Tomoki Nishimura; Sada-atsu Mukai; Shin-ichi Sawada; Kazunari Akiyoshi
ACS Macro Letters, 4(4), 367-371, 2015年04月, 査読有り

Amylose-Based Cationic Star Polymers for siRNA Delivery
Tomoki Nishimura; Kaori Umezaki; Sada-atsu Mukai; Shin-ichi Sawada; Kazunari Akiyoshi
BIOMED RESEARCH INTERNATIONAL, 2015, 962941, 2015年, 査読有り, 招待有り

A bimolecular micelle constructed from amphiphilic pillar[5]arene molecules.
Tomoki Nishimura; Yusuke Sanada; Takuma Matsuo; Tadashi Okobira; Efstratios Mylonas; Naoto Yagi; Kazuo Sakurai
Chemical communications (Cambridge, England), 49(29), 3052-4, 2013年04月, 査読有り

A simple visual sensor with the potential for determining the concentration of fluoride in water at environmentally significant levels
Tomoki Nishimura; Su-Ying Xu; Yun-Bao Jiang; John S. Fossey; Kazuo Sakurai; Steven D. Bull; Tony D. James
CHEMICAL COMMUNICATIONS, 49(5), 478-480, 2013年, 査読有り

Pyrene-anchored boronic acid receptors on carbon nanoparticle supports: fluxionality and pore effects
Katherine Lawrence; Tomoki Nishimura; Peter Haffenden; John M. Mitchels; Kazuo Sakurai; John S. Fossey; Steven D. Bull; Tony D. James; Frank Marken
NEW JOURNAL OF CHEMISTRY, 37(7), 1883-1888, 2013年, 査読有り

Thermodynamics of Lipoplex Formation: Relationship between the Lipid Alkyl Tail Length and Thermodynamic Functions
Shota Fujii; Tomoki Nishimura; Kazuo Sakurai
CHEMISTRY LETTERS, 41(5), 501-503, 2012年05月, 査読有り

A Stimulus-Responsive Shape-Persistent Micelle Bearing a Calix[4]arene Building Block: Reversible pH-Dependent Transition between Spherical and Cylindrical Forms
Shota Fujii; Yusuke Sanada; Tomoki Nishimura; Isamu Akiba; Kazuo Sakurai; Naoto Yagi; Efstratios Mylonas
LANGMUIR, 28(6), 3092-3101, 2012年02月, 査読有り

Quaternary-ammonium-bearing Aromatic Surfactants: Effect of the Alkyl Chain Positions on Their Micelle and DNA-complex Structures
Takuma Matsuo; Shota Fujii; Yumi Kamikawa; Tomoki Nishimura; Yusuke Sanada; Shinichi Mochizuki; Kazuo Sakurai
CHEMISTRY LETTERS, 40(12), 1340-1342, 2011年12月, 査読有り

Metal-ion induced transition from multi- to single-bilayer tubes in histidine bearing lipids and formation of monodisperse Au nanoparticles
Tomoki Nishimura; Takuma Matsuo; Kazuo Sakurai
PHYSICAL CHEMISTRY CHEMICAL PHYSICS, 13(35), 15899-15905, 2011年, 査読有り

Synthesis of a Highly Hydrophobic Cationic Lipid and Structural and Thermodynamic Studies for Interaction with DNA
Tomoki Nishimura; Takeshi Cho; Andrew M. Kelley; Magdalena E. Powell; John S. Fossey; Steven D. Bull; Tony D. James; Hiroyasu Masunaga; Isamu Akiba; Kazuo Sakurai
BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN, 83(9), 1010-1018, 2010年09月, 査読有り

Cation-specific Transition from Vesicle to Lamella for an Aromatic Diamine Lipid in Aqueous Solutions
Tomoki Nishimura; Hiroyasu Masunaga; Hiroki Ogawa; Isamu Akiba; Kazuo Sakurai
CHEMISTRY LETTERS, 39(7), 686-687, 2010年07月, 査読有り

DNA binding of tilorone: H-1 NMR and calorimetric studies of the intercalation
Tomoki Nishimura; Tadashi Okobira; Andrew M. Kelly; Naohiko Shimada; Yoichi Takeda; Kazuo Sakurai
BIOCHEMISTRY, 46(27), 8156-8163, 2007年07月, 査読有り

DNA conformational switching by use of an intercalator and its receptor
Tomoki Nishimura; Yoichi Takeda; Naohiko Shimada; Kazuo Sakurai
CHEMISTRY LETTERS, 36(3), 388-389, 2007年03月, 査読有り

American Chemical Society

日本DDS学会

バイオ・高分子研究会

日本化学会

高分子学会

グラフトポリマーディスク：新規膜タンパク質解析プラットフォーム
科学研究費助成事業, 日本学術振興会, 挑戦的研究(萌芽)
信州大学
2022年06月30日 - 2024年03月31日

ブロックポリマーイオンチャネルの創製
科学研究費助成事業, 日本学術振興会, 基盤研究(B)
信州大学
2022年04月01日 - 2025年03月31日

ブロックポリマーイオンチャネルの創製
科学研究費助成事業, 日本学術振興会, 基盤研究(B)
信州大学
2022年04月01日 - 2025年03月31日

高分子フォルダマーを基盤としたDDSナノファクトリーの創製
科学技術振興機構, 戦略的な研究開発の推進/創発的研究支援事業
2021年 - 2027年

両親媒性ブロック共重合体、分子集合体及びその製造方法並びにタンパク質の内包剤, 特開2015-187148, 特許権
秋吉 一成; 西村; 智貴