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城下 智  ジョウシタ サトル

教員組織学術研究院(医学系)電話番号
教育組織医学部 内科学 第二教室FAX番号
職名准教授メールアドレス
住所〒390-8621 長野県松本市旭3-1-1ホームページURLhttp://www.shinshu-u.ac.jp/faculty/medicine/chair/i-2nai/

プロフィール

研究分野
内科学
消化器内科学
キーワード:慢性肝疾患 , 非侵襲的病態診断法 , ウイルス肝炎 , 自己免疫性肝疾患 , 免疫遺伝学
所属学会
所属学会
日本内科学会
日本肝臓学会
日本消化器病学会
日本消化器内視鏡学会
日本静脈経腸栄養学会
日本超音波医学会
日本人間ドック学会
日本肝癌研究会
American College of Physicians
American Association for the Study of Liver Diseases
European Association for the Study of the Liver
学歴
出身大学院
2010 , 信州大学大学院医学系研究科

出身学校・専攻等(大学院を除く)
2002 , 新潟大学医学部

取得学位
博士(医学) , 信州大学(日本)

免許・資格等
2015年11月 , Fellow of American Collage of Physician
2011年4月 , 日本人間ドック学会認定医
2010年4月 , 日本肝臓学会肝臓専門医
2010年12月 , 日本消化器内視鏡学会専門
2010年10月 , 日本超音波医学会超音波専門医
2009年1月 , 日本消化器病学会消化器病専門医
2008年4月 , 日本がん治療認定医機構がん治療認定医
2008年12月 , 日本内科学会総合内科専門医
2005年7月 , 厚生労働省臨床研修指導医
2003年1月 , 日本医師会認定産業医
2002年9月 , 日本医師会認定健康スポーツ医
受賞学術賞
2020 , 大樹生命厚生財団 特別研究助成
2020 , 日本人間ドック学会英文優秀論文賞
2019 , 新潟大学有壬記念学術奨励賞
2018 , ウイルス肝炎研究財団研究助成事業(研究奨励金)
2018 , 三井生命厚生財団 医学研究助成
2017 , Asian Pacific Digestive Week Federation / Journal   of Gastroenterology and Hepatology Foundation Travel Award
2016 , 日本消化器病学会Young Investigator Travel Award
2016 , 信州大学医学部松医会奨励賞
2010 , Young Investigator the Bursaries of European Association for the Study of the Liver
2009 , 信州医学会賞
2009 , 日本肝臓学会若手奨励賞
2009 , 日本肝臓学会Young Investigator Travel Award
研究職歴等
留学歴
2012-2015 , ワシントン大学医学部(セントルイス)

研究活動業績

研究業績(著書・
発表論文等)
論文
Protocol: Prospective observational study investigating the prevalence and clinical outcome of portopulmonary hypertension in Japanese patients with chronic liver disease
PLoS One,16(4):e0249435 2021(Apr. 01)
Author:Wakabayashi SI, Joshita S (CA), Kimura K, et al.


Primary hepatic extranodal marginal zone lymphoma of muco-sa-associated lymphoid tissue in a patient with chronic hepati-tis B virus infection: Case report and summary of the literature
Medicina,57:280 2021(Mar. 18)
Author:Yamashita Y, Joshita S (CA), Kobayashi H, et al.


Intestinal Obstruction Due to Mesenteric Inflammatory Veno-occlusive Disease: A Case Report and Summary of the Literature
Shinshu Med J,In press 2021(Feb. 03)
Author:Kobayashi H, Joshita S (CA), Nozawa Y, et al.


An Autopsy Case of Primary Biliary Cholangitis with Histological Submassive Hepatic Necrosis Caused by Acute Hepatitis E Virus Infection
Intern Med,In press 2021(Feb. 01)
Author:Koyama M, Yamazaki T, Joshita S (3rd), et al.


Serum thrombospondin 2 is a novel predictor for the severity in the patients with NAFLD
Liver Int.,41(3):505-514 2021(Jan. 20)
Author:Kimura T, Tanaka N, Joshita S (8th), et al.


The ursodeoxycholic acid response score predicts pathological features in primary biliary cholangitis
Hepatol Res.,51(1):80-89 2021(Jan. 01)
Author:Kawata K, Joshita S (2nd), Shimoda S, et al.


Relationship of early acute complications and insertion site in push method percutaneous endoscopic gastrostomy
Sci Rep,10(1):20551 2020(Nov. 25)
Author:Suzuki H (FA), Joshita S (FA), Nagaya T (CA), et al.


Clinical utility of steatohepatitis-related FibroScan-aspartate aminotransferase score for predicting hepatocellular carcinoma in chronic hepatitis C virus patients achieving a sustained virological response by direct-acting antivirals
Alimentary Pharmacology & Therapeutics.,52(7):1222-1223 2020(Oct. 01)
Author:Joshita S (FA), Umemura T (CA).


A case report of pancreatic panniculitis due to acute pancreatitis with intraductal papillary mucinous neoplasm
BMC Gastroenterol.,20(1):286 2020(Aug. 24)
Author:Yamashita Y (FA), Joshita S (CA), Ito T, Maruyama M, Wada S, Umemura T.


A validation study of the Ursodeoxycholic Acid Response Score in Japanese patients with primary biliary cholangitis
Liver Int.,40(8):1926-1933 2020(Aug. 01)
Author:Yagi M, Matsumoto K, Joshita S (15th), et al.


Clinical impact of normal alanine aminotransferase on direct‐acting antiviral outcome in patients with chronic hepatitis C virus infection
JGH Open.,4:574-581 2020(Aug. 01)
Author:Joshita S (FA), Sugiura A (FA), Umemura T (CA), et al.


Polymorphism at rs9264942 is associated with HLA-C expression and inflammatory bowel disease in the Japanese
Sci Rep.,10(1):12424 2020(Jul. 24)
Author:Suzuki H (FA), Joshita S (CA), Hirayama H, et al.


Clinical utility of FibroScan as a non-invasive diagnostic test for primary biliary cholangitis.
J Gastroenterol Hepatol. ,35(7):1208-1214 2020(Jul. 01)
Author:Joshita S (FA/CA), Yamashita Y, Sugiura A, et al.


Effectiveness of Glecaprevir/Pibrentasvir for Hepatitis C: Real-World Experience and Clinical Features of Retreatment Cases.
Biomedicines.,8(4):E74 2020(Apr. 03)
Author:Sugiura A (FA), Joshita S (CA), Yamashita Y, et al.


Clinical In¬fluence of Hepatitis C Virus Eradication by Direct-acting Antivirals on Lipid Levels and “Ningen Dock” Health Check-up Categories in Patients with Chronic Hepatitis C Virus Infection
Ningen Dock International.,7:19-25 2020(Mar. 01)
Author:Joshita S (FA/CA), Sugiura A, Yamazaki T, et al.


Virological Factors Associated With the Occurrence of Hepatitis B Virus (HBV) Reactivation in Patients With Resolved HBV Infection Analyzed Through Ultradeep Sequencing
J Infect Dis.,221(3):400-407 2020(Jan. 14)
Author:Sakamoto K, Umemura T, Joshita S (5th), et al.


KIR/HLA genotypes confer susceptibility and progression in patients with autoimmune hepatitis.
JHEP Rep.,1(5):353-360 2019(Oct. 25)
Author:Umemura T, Joshita S (2nd), Saito H, Yoshizawa K, Norman GL, Tanaka E, Ota M.


Efficacy and Safety of Eradication Therapy for Elderly Patients With Helicobacter Pylori Infection
Medicine (Baltimore).,98(30):e16619 2019(Jul. 20)
Author:Kobayashi S (FA), Joshita S (CA), Yamamoto C, et al.


Long-term Luseogliflozin Therapy Improves Histological Activity of Non-Alcoholic Steatohepatitis Accompanied by Type 2 Diabetes Mellitus
Clin J Gastroenterol.,13(1):83-89 2019(Jul. 10)
Author:Fujimori N, Tanaka N, Joshita S (11th), et al.


Biochemical and Plasma Lipid Responses to Pemafibrate in Patients With Primary Biliary Cholangitis
Hepatol Res.,49(10):1236-1243 2019(Jun. 14)
Author:Joshita S (FA/CA), Umemura T, Yamashita Y, et al.


Bezafibrate Improves GLOBE and UK-PBC Scores and Long-Term Outcomes in Patients With Primary Biliary Cholangitis
Hepatology.,70(6):2035-2046 2019(Apr. 12)
Author:Honda A, Tanaka A, Joshita S (15th), et al.


A Case of Adult T-Cell Leukemia/Lymphoma Complicated With Bilateral Chylothorax
Case Rep Oncol Med.,2019:8357893 2019(Feb. 17)
Author:Kako S (FA), Joshita S (CA), Matsuo A, et al.


POGLUT1, the Putative Effector Gene Driven by rs2293370 in Primary Biliary Cholangitis Susceptibility Locus Chromosome 3q13.33
Sci Rep.,9(1):102 2019(Jan. 14)
Author:Hitomi Y, Ueno K, Joshita S (57th), et al.


Improvement of porphyria cutanea tarda following treatment of hepatitis C virus by direct-acting antivirals: A case report.
J Dermatol. ,46(5):e149-e151 2018(Nov. 03)
Author:Nihei T, Kiniwa Y, Joshita S (4th), et al.


Quantitative analysis of serum chemokines associated with treatment failure of direct-acting antivirals in chronic hepatitis C.
Cytokine.,111(1):357-363 2018(Oct. 05)
Author:Umemura T, Yamazaki T, Joshita S (3rd), et al.


Past history of hepatocellular carcinoma is an independent risk factor of treatment failure in patients with chronic hepatitis C virus infection receiving direct-acting antivirals.
J Viral Hepat.,25(12):1462-1471 2018(Aug. 30)
Author:Sugiura A (FA), Joshita S (FA), Umemura T (CA), et al.


A cis-eQTL of HLA-DPB1 Affects Susceptibility to Type 1 Autoimmune Hepatitis.
Sci Rep.,8(1):11924 2018(Aug. 09)
Author:Yamazaki T, Umemura T, Joshita S (3rd), et al.


Miglitol attenuates non-alcoholic steatohepatitis in diabetic patients.
Hepatol Res.,48(13):1092-1098 2018(Jul. 27)
Author:Komatsu M, Tanaka N, Joshita S (10th), et al .


Serum Autotaxin Is a Useful Disease Progression Marker in Patients with Primary Biliary Cholangitis.
Sci Rep.,8(1):8159 2018(May 25)
Author:Joshita S (FA), Umemura T (CA), Usami Y, et al.


Serum autotaxin levels are correlated with hepatic fibrosis and ballooning in patients with non-alcoholic fatty liver disease.
World J Gastroenterol.,24(11):1239-1249 2018(May 21)
Author:Fujimori N, Umemura T, Joshita S (7th), et al.


Salmonella Enteritidis cholecystitis with chronic granulomatous disease.
IDCases.,12(1):49-52 2018(May 14)
Author:Yamashita Y, Kimura T, Joshita S (6th). et al.


KIR2DL2 combined with HLA-C1 confers risk of hepatitis C virus-related hepatocellular carcinoma in younger patients.
Oncotarget.,9(28):19650-19661 2018(Apr. 13)
Author:Saito H, Umemura T, Joshita S (3rd), et al.


Association between KIR-HLA combination and ulcerative colitis and Crohn's disease in a Japanese population.
PLoS One.,13(4):e0195778 2018(Apr. 12)
Author:Saito H, Hirayama A, Joshita S (4th), et al.


Mild drinking habit is a risk factor for hepatocarcinogenesis in non-alcoholic fatty liver disease with advanced fibrosis.
World J Gastroenterol. ,24(13):1440-1450 2018(Apr. 07)
Author:Kimura T, Tanaka N, Joshita S (6th), et al.


Changes in serum levels of autotaxin with direct-acting antiviral therapy in patients with chronic hepatitis C.
PLoS One.,13(4):e0195632 2018(Apr. 04)
Author:Yamazaki T (FA), Joshita S (FA), Umemura T (CA), et al.


Clinical features of autoimmune hepatitis with acute presentation: a Japanese nationwide survey.
J Gastroenterol.,53(9):1079-1088 2018(Feb. 23)
Author:Joshita S (FA), Yoshizawa K (CA), Umemura T, et al.


Emergence of anti-mitochondrial M2 antibody in patient with angioimmunoblastic T-cell lymphoma.
Clin J Gastroenterol.,11(4):302-308 2018(Feb. 10)
Author:Wakabayashi SI, Kimura T, Joshita S (4th), et al.


長期経過加療中の非肝硬変期に肝細胞癌を合併した原発性胆汁性胆管炎の2例
信州医学雑誌,66(1):39-49 2018(Feb. 10)
Author:杉浦亜弓, 城下智, 山下裕騎, 木村岳史, 山崎智生, 藤森尚之, 小松通治, 松本晶博, 小林翔太, 梅村武司, 田中榮司


Astrocyte-derived interleukin-33 promotes microglial synapse engulfment and neural circuit development.
Science.,359(6381):1269-1273 2018(Feb. 01)
Author:Vainchtein ID, Chin G, Joshita S (12th), et al.


Renal Impairment Is Associated With Increased Risk of Mortality in Patients With Cirrhosis: A Retrospective Cohort Study
Medicine (Baltimore).,98(6):e14475 2018(Feb. 01)
Author:Umemura T, Joshita S (2nd), Shibata S, et al.


Humanized TREM2 mice reveal microglia-intrinsic and -extrinsic effects of R47H polymorphism.
J Exp Med.,215(3):745-760 2018(Jan. 10)
Author:Song WM (FA), Joshita S (FA), Zhou Y, et al.


A case of liver abscess co-infected with Desulfovibrio desulfuricans and Escherichia coli and review of the literature.
J Infect Chemother.,24(5):393-397 2017(Dec. 18)
Author:Yamazaki T (FA), Joshita S (CA), Kasuga E, et al.


Serum autotaxin is a useful liver fibrosis marker in patients with chronic hepatitis B virus infection.
Hepatol Res.,48(4):275-285 2017(Dec. 04)
Author:Joshita S (FA), Ichikawa Y (FA), Umemura T (CA), et al.


Genetics and epigenetics in the pathogenesis of primary biliary cholangitis.
Clin J Gastroenterol.,11(1):11-18 2017(Nov. 20)
Author:Joshita S (FA/CA), Umemura T, Tanaka E, Ota M.


Association of autoimmune hepatitis with Src homology 2 adaptor protein 3 gene polymorphisms in Japanese patients
J Hum Genet.,62(11):963-967 2017(Nov. 01)
Author:Umemura T, Joshita S (2nd), Hamano H, et al.


Cimetidine/lactulose therapy ameliorates erythropoietic protoporphyria-related liver injury
Clin J Gastroenterol.,10(5):452-458 2017(Oct. 01)
Author:Fujimori N, Komatsu M, Joshita S (13th), et al.


Association between lower air pressure and the onset of ischemic colitis: a case-control study
Eur J Gastroenterol Hepatol.,29(9):1071-1078 2017(Sep. 01)
Author:Kimura T, Akihiro S, Joshita S (7th), et al.


Association between serum soluble CD14 and IL-8 levels and clinical outcome in primary biliary cholangitis
Liver Int.,37(6):897-905 2017(Jun. 01)
Author:Umemura T, Sekiguchi T, Joshita S (3rd), et al.


Clinicopathological characteristics of non-B non-C hepatocellular carcinoma without past hepatitis B virus infection.
Hepatol Res. ,47(5):405-418 2017(Apr. 01)
Author:Kimura T, Kobayashi A, Joshita S (10th), et al.


Association of Serum Autotaxin Levels with Liver Fibrosis in Patients with Chronic Hepatitis C
Sci Rep.,20(7):46705 2017(Apr. 01)
Author:Yamazaki T (FA), Joshita S (FA), Umemura T (CA), et al.


A Patency Capsule Remained Intact in the Colon over 210 Hours.
,2017(2017):1201404 2017(Feb. 22)
Author:Hihara Y, Joshita S (CA), Takahashi T, et al.


Genome-wide association studies identify PRKCB as a novel genetic susceptibility locus for primary biliary cholangitis in the Japanese population.
Hum Mol Genet.,26(3):650-659 2017(Feb. 01)
Author:Kawashima M, Hitomi Y, Joshita S (33th), et al.


Genetic Contribution to the Pathogenesis of Primary Biliary Cholangitis
J Immunol Res.,2017:3073504 2017(Feb. 01)
Author:Joshita S (FA/CA), Umemura T, Tanaka E, Ota M.


Association between endotoxemia and histological features of nonalcoholic fatty liver disease
World J Gastroenterol.,23(4):712-722 2017(Jan. 28)
Author:Kitabatake H, Tanaka N, Joshita S (12th), et al.


Lymphocyte Antigen 75 Polymorphisms Are Associated with Disease Susceptibility and Phenotype in Japanese Patients with Inflammatory Bowel Disease.
Dis Markers.,2016(2016):6485343 2016(Nov. 14)
Author:Hirayama A, Joshita S (CA), Kitahara K, et al.


Liver stiffness-spleen size-to-platelet ratio risk score identifies esophageal varices in Japanese patients with chronic hepatitis C.
Hepatol Res,46(9):884-9 2016(Aug. 01)
Author:Shibata S, Umemura T, Joshita S (7th), et al.


Incidence and prevalence of autoimmune hepatitis in the Ueda area, Japan.
Hepatol Res,46(9):878-83 2016(Aug. 01)
Author:Yoshizawa K, Joshita S (2nd), Matsumoto A, et al.


Liver stiffness-spleen size-to-platelet ratio risk score detects esophageal varices in chronic liver disease.
Springerplus,5(1):998 2016(Jul. 07)
Author:Shibata S (FA), Joshita S (FA), Umemura T (CA), et al.


Genetic Association of PTPN22 Polymorphisms with Autoimmune Hepatitis and Primary Biliary Cholangitis in Japan.
Sci Rep,6:29770 2016(Jun. 11)
Author:Umemura T, Joshita S (2nd), Yamazaki T, et al.


Serum Wisteria floribunda agglutinin-positive human Mac-2 binding protein may predict liver fibrosis and progression to hepatocellular carcinoma in patients with chronic hepatitis B virus infection.
Hepatol Res.,47(2):226-233 2016(Apr. 22)
Author:Ichikawa Y (FA), Joshita S (FA), Umemura T (CA), et al.


Serum cell death biomarkers for prediction of liver fibrosis and poor prognosis in primary biliary cirrhosis.
PLoS One,10(6):e0131658 2015(Jun. 25)
Author:Sekiguchi T, Umemura T, Joshita S (7th), et al.


Serum Wisteria floribunda Agglutinin-Positive Mac-2-Binding Protein Level Predicts Liver Fibrosis and Prognosis in Primary Biliary Cirrhosis.
Am J Gastroenterol,110(6):857-64 2015(Jun. 01)
Author:Umemura T (FA/CA), Joshita S (FA), Sekiguchi T, et al.


Steatogenesis in adult-onset type II citrullinemia is associated with down-regulation of PPARα.
Biochim Biophys Acta,1852(3):473-81 2015(Mar. 01)
Author:Komatsu M, Kimura T, Joshita S (9th), et al.


【C型肝炎治療update】 治療 IFNβ+リバビリン併用療法
日本臨床,73(2):273-279 2015(Feb. 01)
Author:城下智, 田中榮司


AST/platelet ratio index associates with progression to hepatic failure and correlates with histological fibrosis stage in Japanese patients with primary biliary cirrhosis.
J Hepatol.,61(6):1443-5 2014(Dec. 01)
Author:Joshita S (FA/CA), Umemuta T, Ota M, Tanaka E.


Characteristics and prediction of hepatitis B e-antigen negative hepatitis following seroconversion in patients with chronic hepatitis B.
Hepatol Res. ,44(10):E45-53 2014(Oct. 01)
Author:Morita S, Matsumoto A, Joshita S (8th), et al.


Serum levels of interleukin-22 and hepatitis B core-related antigen are associated with treatment response to entecavir therapy in chronic hepatitis B.
Hepatol Res.,44(10):E172-80 2014(Oct. 01)
Author:Okuhara S, Umemura T, Joshita S (3rd), et al.


KIR3DL1-HLA-Bw4 combination and IL28B polymorphism predict response to Peg-IFN and ribavirin with and without telaprevir in chronic hepatitis C.
Hum Immunol. ,75(8):822-6 2014(Aug. 01)
Author:Umemura T, Ota M, Joshita S (11th), et al,.


Laparoscopic findings of congenital hepatic fibrosis: A case report and review of the published work.
Hepatol Res. ,44(7):818-24 2014(Jul. 01)
Author:Komatsu M, Tanaka N, Joshita S (7th), et al.


Human Leukocyte Antigen Class II Haplotypes Affect Clinical Characteristics and Progression of Type 1 Autoimmune Hepatitis in Japan
PLoS One.,9(6):e100565 2014(Jun. 01)
Author:Umemura T, Katsuyama Y, Joshita S (5th), et al.


STAT4 Gene Polymorphisms Are Associated with Susceptibility and ANA Status in Primary Biliary Cirrhosis
Dis Markers.,2014:727393 2014(Feb. 04)
Author:Joshita S (FA), Umemura T (CA), Makamura M, et al.


Genetic polymorphism in IFNL4 and response to pegylated interferon-α and ribavirin in Japanese chronic hepatitis C patients.
Tissue Antigens.,83(1):45-8 2014(Jan. 01)
Author:Nozawa Y, Umemura Y, Joshita S (7th), et al.


KIR, HLA, and IL28B variant predict response to antiviral therapy in genotype 1 chronic hepatitis C patients in Japan.
PLoS One,8(12):e83381 2013(Dec. 12)
Author:Nozawa Y, Umemura T, Joshita S (3rd), et al.


Cutaneous sarcoidosis in a chronic hepatitis C patient receiving pegylated interferon and ribavirin therapy
Hepatol Res. ,43(7):801-807 2013(May 15)
Author:Joshita S (FA/CA), Shirahata K, Yazaki Y, et al.


Association analysis of toll-like receptor 4 polymorphisms in Japanese primary biliary cirrhosis
Hum Immunol. ,74(2):219-222 2013(Jan. 01)
Author:Morita S (FA), Joshita S (FA), Umemura T (CA)m et al.


Liver Dysfunction and Thrombocytopenia Diagnosed as Intravascular Large B-cell Lymphoma Using a Timely and Accurate Transjugular Liver Biopsy
Intern Med.,52(17):1903-1908 2013(Jan. 01)
Author:Sekiguchi N, Joshita S (CA), Yoshida T, et al.


Genome-wide association study identifies TNFSF15 and POU2AF1 as susceptibility loci for primary biliary cirrhosis in the Japanese population
Am J Hum Genet.,91(4):721-728 2012(Sep. 20)
Author:Nakamura M, Nishida N, Joshita S (42th), et al.


Super high resolution for single molecule-sequence-based typing of classical HLA loci at the 8-digit level using next generation sequencers
Tissue Antigens.,80(4):305-316 2012(Aug. 04)
Author:Shiina T, Suzuki S, Joshita S (9th), et al.


Long-term outcome of Japanese patients with type 1 autoimmune hepatitis
Hepatology.,56(2):668-676 2012(Jul. 06)
Author:Yoshizawa K, Matsumoto A, Joshita S (5th), et al.


Changes in the serum level of hepatitis B virus (HBV) surface antigen over the natural course of HBV infection
J Gastroenterol.,47(9):1006-1013 2012(Feb. 29)
Author:Matsumoto A, Tanaka E, Joshita S (LA), et al.


Association of IL28B gene polymorphism with development of hepatocellular carcinoma in Japanese patients with chronic hepatitis C virus infection
Hum Immunol. ,73(3):298-300 2012(Jan. 01)
Author:Joshita S (FA), Umemura T, Katsuyama Y, et al.


Human leukocyte antigen class II molecules confer both susceptibility and progression in Japanese patients with primary biliary cirrhosis
Hepatology.,55(2):506-511 2011(Nov. 19)
Author:Umemura T, Joshita S (2nd), Ichijo T, et al.


Serum interleukin (IL)-10 and IL-12 levels and IL28B gene polymorphisms: pretreatment prediction of treatment failure in chronic hepatitis C
Antivir Ther.,16(7):1073-1080 2011(Oct. 01)
Author:Umemura T, Joshita S (2nd), Yoneda S, et al.


A Case of Pyogenic Liver Abscess Infected with Fusobacterium necrophorum Depicted by Microscopy and Confirmed by Tissue Culture
Intern Med.,50(17):1815-1819 2011(Sep. 01)
Author:Nozawa Y, Joshita S (CA), Fukushima M, et al.


Early detection of interstitial pneumonia by monitoring KL-6 in a chronic hepatitis C patient undergoing pegylated interferon and ribavirin therapy
Hepatol Res.,41(9):904-909 2011(Sep. 01)
Author:Ichikawa-Yamada Y, Joshita S (CA), Tsukahara Y, et al.


Genetic polymorphisms in CTLA4 and SLC4A2 are differentially associated with the pathogenesis of primary biliary cirrhosis in Japanese patients
J Gastroenterol.,46(10):1203-1212 2011(May 19)
Author:Aiba Y, Nakamura M, Joshita S (3rd), et al.


Serum chemokine levels are associated with the outcome of pegylated interferon and ribavirin therapy in patients with chronic hepatitis C
Hepatol Res.,41(6):587-593 2011(Apr. 19)
Author:Yoneda S, Umemura T, Joshita S (3rd), et al.


Association of serum cytokine levels with treatment response to pegylated interferon and ribavirin therapy in genotype 1 chronic hepatitis C patients
J Infect Dis.,203(8):1087-1095 2011(Mar. 11)
Author:Yoneda S, Umemura T, Joshita S (5th), et al.


Cytokine profiles affecting the pathogenesis of autoimmune hepatitis in Japanese patients
Hepatol Res.,41(4):350-357 2011(Feb. 24)
Author:Kamijo A, Yoshizawa K, Joshita S (3rd), et al.


Clinical significance of immunoglobulin G4-associated autoimmune hepatitis
J Gastroenterol.,46 Suppl 1:48-55 2011(Jan. 01)
Author:Umemura T, Zen Y, Joshita S (4th), et al.


Accurate and simple method for quantification of hepatic fat content using magnetic resonance imaging: a prospective study in biopsy-proven nonalcoholic fatty liver disease
J Gastroenterol.,45(12):1263-1271 2010(Jul. 13)
Author:Hatta T, Fujinaga Y, Joshita S (10th), et al.


Down-regulation of SREBP-1c is associated with the development of burned-out NASH.
J Hepatol.,53(4):724-31 2010(Jul. 01)
Author:Nagaya T, Tanaka N, Joshita S (9th), et al.


Serum Fragmented Cytokeratin 18 Levels Reflect the Histologic Activity Score of Nonalcoholic Fatty Liver Disease More Accurately Than Serum Alanine Aminotransferase Levels
J Clin Gastroenterol. ,44(6):440-447 2010(Jun. 01)
Author:Tsutsui M, Tanaka N, Joshita S (8th), et al.


A Patient with Advanced Hepatocellular Carcinoma Treated with Sorafenib Tosylate Showed Massive Tumor Lysis with Avoidance of Tumor Lysis syndrome
Intern Med,49(11):991-994 2010(Jun. 01)
Author:Joshita S (FA/CA), Yoshizawa K, Sano K, et al.


Association analysis of cytotoxic T-lymphocyte antigen 4 gene polymorphisms with primary biliary cirrhosis in Japanese patients
J Hepatol.,53(3):537-541 2010(May 25)
Author:Joshita S (FA), Umemura Takeji, Yoshizawa K, et al.


A2BP1 as a novel susceptible gene for primary biliary cirrhosis in Japanese patients
Hum Immunol,71(5):520-524 2010(May 06)
Author:Joshita S (FA), Umemura T, Yoshizawa K, et al.


A Case of Granulocyte-Colony Stimulating Factor-Producing Hepatocellular Carcinoma Confirmed by Immunohistochemistry
J Korean Med Sci. ,25(3):476-480 2010(Feb. 17)
Author:Joshita S (CA/FA), Nakazawa K, Koike S, et al.


Primitive Neuroectodermal Tumor as a Differential Diagnosis of CD56-Positive Tumors in Adults
Intern Med,48(15):1267-1272 2009(Aug. 03)
Author:Nagaya T, Tanaka N, Joshita S (4th), et al.


Granulocyte-Colony Stimulating Factor-Producing Pancreatic Adenosquamous Carcinoma Showing Aggressive Clinical Course
Intern Med,48(9):687-691 2009(May 01)
Author:Joshita S (FA/CA), Nakazawa Koh, Sugiyama Y, et al.


A case of well-differentiated cholangiolocellular carcinoma visualized with contrast-enhanced ultrasonography using Sonazoid
Hepatol Res,39(2):207-212 2009(Feb. 01)
Author:Joshita S (FA/CA), Ichijo T, Suzuki F, et al.


Pretreatment prediction of virological response to peginterferon plus ribavirin therapy in chronic hepatitis C patients using viral and host factors.
Hepatolgy.,48(6):1753-60 2008(Dec. 01)
Author:Shirakawa H, Matsumoto A, Joshita S (3rd), et al.


Development from simple steatosis to liver cirrhosis and hepatocellular carcinoma: a 27-year follow-up case.
Clin J Gastroenterol.,1(3):116-121 2008(Oct. 01)
Author:Nagaya T, Tanaka N, Joshita S (7th), et al.


Zygomycosis presenting as acute myocardial infarction during hematological malignancies
Intern Med.,47(9):839-842 2008(May 01)
Author:Joshita S (FA/CA), Kitano K, Nagaya T, et al.


Thrombotic thrombocytopenic purpura associated with pegylated-interferon alpha-2a by an ADAMTS13 inhibitor in a patient with chronic hepatitis C.
Haematologica.,91(8):ECR34 2006(Aug. 01)
Author:Kitano K, Gibo Y, Joshita S (6th), et al.

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