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木庭 幸子  キニワ ユキコ

教員組織学術研究院(医学系)電話番号
教育組織医学部 医学科 皮膚科学FAX番号
職名准教授メールアドレス
住所ホームページURLhttp://www.shinshu-u.ac.jp/faculty/medicine/chair/i-hifu/index.html

プロフィール

研究分野
皮膚腫瘍学
腫瘍免疫学
免疫アレルギー
現在の研究課題
メラノーマにおける循環腫瘍細胞の同定と解析
キーワード:循環腫瘍細胞 , メラノーマ
がんのエネルギー代謝と転移メカニズムの解析
キーワード:がんの転移
メラノーマに対するプレシジョン医療の開発
キーワード:プレシジョン医療 , 免疫療法 , 分子標的治療 , メラノーマ
全エクソーム解析による乳房外Paget病の遺伝子異常の解明
キーワード:乳房外Paget病 , 全エクソーム解析
所属学会
所属学会
Society for Melanoma Research
日本皮膚免疫アレルギー学会
日本アレルギー学会
日本皮膚悪性腫瘍学会
日本研究皮膚科学会
日本免疫学会
日本がん免疫学会
日本皮膚科学会

所属学会役職担当
2021- , 日本皮膚悪性腫瘍学会 , 事務局長
2020- , 日本皮膚免疫アレルギー学会 , 代議員
2018- , 日本皮膚科学会 , 代議員
2013- , 日本研究皮膚科学会 , 評議員
2017-2020 , 日本皮膚悪性腫瘍学会 , 雑誌委員会・編集幹事
学歴
出身学校・専攻等(大学院を除く)
1993 , 信州大学 , 医学部 , 医学科

取得学位
医学博士 , 信州大学

免許・資格等
2016 , 日本アレルギー学会 アレルギー専門医
2010 , 日本がん治療認定医
2001 , 日本皮膚科学会認定皮膚科専門医・指導医
1993 , 医師免許
研究職歴等
研究職歴
2018- , 准教授
2011-2018 , 信州大学医学部附属病院・講師
2006-2011 , 信州大学医学部皮膚科、助教
2003-2006 , ベイラー医科大学,博士研究員
2000-2003 , 信州大学医学部皮膚科、医員
1998-2000 , 慶応義塾大学先端医科学研究所、共同研究員

研究職歴以外の職歴
2000-2003 , 信州大学医学部皮膚科 医員
1995-1996 , 長野赤十字病院皮膚科
1993-1998 , 信州大学医学部皮膚科、研修医、医員

留学歴
2003-2006 , ベイラー医科大学

研究活動業績

研究業績(著書・
発表論文等)
書籍等出版物
悪性黒色腫 免疫療法:特にIFN-β, IFN-α, IL-2について, 皮膚の悪性腫瘍 (皮膚科臨床アセット 17) , 72-77
中山書店 (総編集:古江増隆,専門編集:山﨑直也) 2014(Jun. 21)
Author:木庭 幸子


悪性黒色腫の免疫療法, 1冊でわかる皮膚がん
文光堂(斎田俊明、宮地良樹、清水宏、編) 2011(Feb. 07)
Author:木庭幸子


メラノーマに免疫療法は有効か?, EBMがん化学療法・分子標的治療法2011-2012 , 602-608
中外医学社(西條長宏 監修) 2010(Nov.)
Author:木庭幸子


論文
Real-world efficacy of anti-PD-1 antibody or combined anti-PD-1 plus anti-CTLA-4 antibodies, with or without radiotherapy, in advanced mucosal melanoma patients: A retrospective, multicenter study
EUROPEAN JOURNAL OF CANCER,157:361-372 2021(Nov.)
Author:Umeda, Yoshiyasu; Yoshikawa, Shusuke; Kiniwa, Yukiko; Maekawa, Takeo; Yamasaki, Osamu; Isei, Taiki; Matsushita, Shigeto; Nomura, Motoo; Nakai, Yasuo; Fukushima, Satoshi; Saito, Shintaro; Takenouchi, Tatsuya; Tanaka, Ryo; Kato, Hiroshi; Otsuka, Atsushi; Matsuya, Taisuke; Baba, Natsuki; Nagase, Kotaro; Inozume, Takashi; Onuma, Takehiro; Kuwatsuka, Yutaka; Fujimoto, Noriki; Kaneko, Takahide; Onishi, Masazumi; Namikawa, Kenjiro; Yamazaki, Naoya; Nakamura, Yasuhiro;
Keywords:Mucosal melanoma; Radiotherapy; Abscopal effect; Anti-PD-1 antibody; Anti-CTLA-4 antibody; Nivolumab; Pembrolizumab; Ipilimumab;


Increased expression of secreted protein acidic and rich in cysteine and tissue inhibitor of metalloproteinase-3 in epidermotropic melanoma metastasis
J Dermatol 2021(Aug. 29)
Author:Maureen Tania Meling, Yukiko Kiniwa, Eisaku Ogawa, Yuki Sato, Ryuhei Okuyama


Case of annular pustular psoriasis/circinate erythematous psoriasis induced by hydroxychloroquine in a patient with systemic lupus erythematosus: Possible association with CARD-14 mutation
J Dermatol 2021(Jun. 02)
Author:Hirotaka Midorikawa, Yukiko Kiniwa, Akane Minagawa, Kana Osawa, Takushi Shirai, Tasuku Sano, Kenta Nakamura, Atsuko Ashida, Ken-Ichi Ueno, Takuya Takeichi, Masashi Akiyama, Ryuhei Okuyama


CCL5 production by fibroblasts through a local renin–angiotensin system in malignant melanoma affects tumor immune responses.
J Cancer Res Clin Oncol 2021(Mar. 26)
Author:Nakamura K, Kiniwa Y, Okuyama R.


Usefulness of monitoring circulating tumor cells as a therapeutic biomarker in melanoma with BRAF mutation
BMC Cancer,21(1):287 2021(Mar. 17)
Author:Kiniwa Y, Nakamura K, Mikoshiba A, Ashida A, Akiyama Y, Morimoto A, Okuyama R


Recent advances in molecular targeted therapy for unresectable and metastatic BRAF-mutated melanoma.
Jpn J Clin Oncol,51(3):315-20 2021(Mar.)
Author:Kiniwa Y, Okuyama R


Ligand bound fatty acid binding protein 7 (FABP7) drives melanoma cell proliferation via modulation of Wnt/β-catenin signaling.
Pharm Res,38(3):479-490 2021(Mar.)
Author:Umaru BA, Kagawa Y, Shil SK, Arakawa N, Pan Y, Miyazaki H, Kobayashi S, Yang S, Cheng A, Wang Y, Shinoda Y, Kiniwa Y, Okuyama R, Fukunaga K, Owada Y


Case of bullous pemphigoid following coronavirus disease 2019 vaccination
JOURNAL OF DERMATOLOGY 2021
Author:Nakamura, Kenta; Kosano, Megumi; Sakai, Yuzuki; Saito, Nana; Takazawa, Yuko; Omodaka, Toshikazu; Kiniwa, Yukiko; Okuyama, Ryuhei;


Successful treatment of cutaneous infection due toPurpureocillium lilacinumusing voriconazole
JOURNAL OF DERMATOLOGY,47(9):E342-E343 2020(Sep.)
Author:Suzuki, Rika; Kiniwa, Yukiko; Shirai, Takushi; Takazawa, Yuko; Natori, Tatsuya; Mochizuki, Takashi; Okuyama, Ryuhei;


Paraneoplastic pemphigus associated with Waldenstrom's macroglobulinemia
JOURNAL OF DERMATOLOGY,47(5):E200-E201 2020(May)
Author:Shirai, Takushi; Kiniwa, Yukiko; Ishii, Norito; Hashimoto, Takashi; Senoo, Yasushi; Urushihata, Kazuhisa; Ashida, Atsuko; Okuyama, Ryuhei;


Detecting copy number alterations of oncogenes in cell-free DNA to monitor treatment response in acral and mucosal melanoma
JOURNAL OF DERMATOLOGICAL SCIENCE,97(3):172-178 2020(Mar.)
Author:Mikoshiba, Asuka; Ashida, Atsuko; Sakaizawa, Kaori; Kiniwa, Yukiko; Okuyama, Ryuhei;


p63 overexpression in the epidermis of spiny keratoderma
JOURNAL OF DERMATOLOGY,47(1):E29-E30 2020(Jan.)
Author:Widyasaputra, Maureen Tania; Ogawa, Eisaku; Saiki, Minoru; Kiniwa, Yukiko; Okuyama, Ryuhei;


BRAF Mutation Heterogeneity in Melanoma Lesions
ACTA DERMATO-VENEREOLOGICA,100(1):adv00045 2020(Jan.)
Author:Sakaizawa, Kaori; Ashida, Atsuko; Kiniwa, Yukiko; Okuyama, Ryuhei;


Hemophagocytic syndrome associated with pembrolizumab therapy successfully controlled by cyclosporin
JOURNAL OF DERMATOLOGY 2020
Author:Sakai, Yuzuki; Nakamura, Kenta; Midorikawa, Hirotaka; Osawa, Kana; Shirai, Takushi; Sano, Tasuku; Kiniwa, Yukiko; Nakazawa, Hideyuki; Okuyama, Ryuhei;


Anti-PD1 checkpoint inhibitor therapy in acral melanoma: a multicenter study of 193 Japanese patients.
Ann Oncol,31(9):1198-1206 2020
Author:Nakamura Y, Namikawa K, Yoshino K, Yoshikawa S, Uchi H, Goto K, Nakamura Y, Fukushima S, Kiniwa Y, Takenouchi T, Uhara H, Kawai T, Hatta N, Funakoshi T, Teramoto Y, Otsuka A, Doi H, Ogata D, Matsushita S, Isei T, Hayashi T, Shibayama Y, Yamazaki N.


Circulating Tumour DNA Reflects Tumour Burden Independently of Adverse Events Caused by Systemic Therapies for Melanoma
ACTA DERMATO-VENEREOLOGICA,99(12):1184-1185 2019(Nov.)
Author:Ashida, Atsuko; Sakaizawa, Kaori; Mikoshiba, Asuka; Kiniwa, Yukiko; Okuyama, Ryuhei;


Thymoma-associated graft-versus-host-like disease treated with high-dose i.v. immunoglobulin
JOURNAL OF DERMATOLOGY,46(6):E224-E225 2019(Jun.)
Author:Sato, Yuki; Shirota, Shiho; Kiniwa, Yukiko; Sekiguchi, Nodoka; Okuyama, Ryuhei; Koizumi, Tomonobu;


Improvement of porphyria cutanea tarda following treatment of hepatitis C virus by direct-acting antivirals: A case report
JOURNAL OF DERMATOLOGY,46(5):E149-E151 2019(May)
Author:Nihei, Tatsuya; Kiniwa, Yukiko; Mikoshiba, Yasutomo; Joshita, Satoru; Okuyama, Ryuhei;


Identification of genetic alterations in extramammary Paget disease using whole exome analysis
JOURNAL OF DERMATOLOGICAL SCIENCE,94(1):229-235 2019(Apr.)
Author:Kiniwa, Yukiko; Yasuda, Jun; Saito, Sakae; Saito, Rumiko; Motoike, Ikuko N.; Danjoh, Inaho; Kinoshita, Kengo; Fuse, Nobuo; Yamamoto, Masayuki; Okuyama, Ryuhei;


Presence of antibodies to striated muscle and acetylcholine receptor in association with occurrence of myasthenia gravis with myositis and myocarditis in a patient with melanoma treated with an anti-programmed death 1 antibody
EUROPEAN JOURNAL OF CANCER,106:193-195 2019(Jan.)
Author:Shirai, T.; Kiniwa, Y.; Sato, R.; Sano, T.; Nakamura, K.; Mikoshiba, Y.; Ohashi, N.; Sekijima, Y.; Okuyama, R.;


3.悪性黒色腫の発癌に関わる分子異常と治療への応用
日本皮膚科学会雑誌,129(11):2307-2312 2019
Author:木庭 幸子


遺伝性血管性浮腫の診断と治療
日本耳鼻咽喉科学会会報,122(11):1457-1459 2019
Author:木庭 幸子


Sarcoidosis mimicking malar rash: a case of lupus pernio
EUROPEAN JOURNAL OF DERMATOLOGY,29(3):331-332 2019
Author:Sato, Rika; Kiniwa, Yukiko; Shirai, Takushi; Okuyama, Ryuhei;


Real-world efficacy of anti-PD-1 antibodies in advanced acral melanoma patients: A retrospective, multicenter study (JAMP study).
JOURNAL OF CLINICAL ONCOLOGY,37(15) 2019
Author:Nakamura, Yasuhiro; Namikawa, Kenjiro; Yoshino, Koji; Yoshikawa, Shusuke; Uchi, Hiroshi; Goto, Katsunobu; Nakamura, Yoshiyuki; Fukushima, Satoshi; Kiniwa, Yukiko; Takenouchi, Tatsuya; Uhara, Hisashi; Kawai, Toru; Hatta, Naohito; Funakoshi, Takeru; Teramoto, Yukiko; Otsuka, Atsushi; Doi, Haruki; Ogata, Dai; Matsushita, Shigeto; Yamazaki, Naoya;


Type 1 diabetes in a melanoma patient treated with ipilimumab after nivolumab
JOURNAL OF DERMATOLOGY,45(10):E289-E290 2018(Oct.)
Author:Omodaka, Toshikazu; Kiniwa, Yukiko; Sato, Yuki; Suwa, Manabu; Sato, Misato; Yamaguchi, Tomohiko; Sato, Ai; Miyake, Tomomi; Okuyama, Ryuhei;


Diversity of circulating tumor cells in peripheral blood: Detection of heterogeneous BRAF mutations in a patient with advanced melanoma by single-cell analysis
JOURNAL OF DERMATOLOGICAL SCIENCE,90(2):211-213 2018(May)
Author:Kiniwa, Yukiko; Nakamura, Kenta; Mikoshiba, Asuka; Akiyama, Yasuyuki; Morimoto, Atsushi; Okuyama, Ryuhei;


Involvement of local renin-angiotensin system in immunosuppression of tumor microenvironment
CANCER SCIENCE,109(1):54-64 2018(Jan.)
Author:Nakamura, Kenta; Yaguchi, Tomonori; Ohmura, Gaku; Kobayashi, Asuka; Kawamura, Naoshi; Iwata, Takashi; Kiniwa, Yukiko; Okuyama, Ryuhei; Kawakami, Yutaka;


Expression of Mucin 1 in Mycosis Fungoides Tumour Cells: A Case Report
ACTA DERMATO-VENEREOLOGICA,97(6):747-748 2017(Jun.)
Author:Shirai, Takushi; Kiniwa, Yukiko; Asaka, Shiho; Shimojo, Yasuyo; Kamijo, Fuminao; Okuyama, Ryuhei;


Hypohidrotic ectodermal dysplasia: A report of two cases
JOURNAL OF DERMATOLOGY,44(4):479-481 2017(Apr.)
Author:Miyake, Tomomi; Kiniwa, Yukiko; Kosho, Tomoki; Nakano, Hajime; Okuyama, Ryuhei;


Polyarteritis nodosa in a patient with haemophilia A
EUROPEAN JOURNAL OF DERMATOLOGY,27(2):203-204 2017(Mar.)
Author:Tsuji, Asuka; Kiniwa, Yukiko; Kamijo, Fuminao; Miyake, Tomomi; Ohashi, Atsuko; Senoo, Noriko; Urushihata, Kazuhisa; Okuyama, Ryuhei;


Cutaneous plasmacytosis associated with autoimmune hemolytic anemia
JOURNAL OF DERMATOLOGY,43(3):343-345 2016(Mar.)
Author:Kiniwa, Yukiko; Matoba, Hisanori; Hamano, Hideaki; Senoo, Yasushi; Okuyama, Ryuhei;


Intratumoral expression levels of PD-L1, GZMA, and HLA-A along with oligoclonal T cell expansion associate with response to nivolumab in metastatic melanoma
ONCOIMMUNOLOGY,5(9) 2016
Author:Inoue, Hiroyuki; Park, Jae-Hyun; Kiyotani, Kazuma; Zewde, Makda; Miyashita, Azusa; Jinnin, Masatoshi; Kiniwa, Yukiko; Okuyama, Ryuhei; Tanaka, Ryota; Fujisawa, Yasuhiro; Kato, Hiroshi; Morita, Akimichi; Asai, Jun; Katoh, Norito; Yokota, Kenji; Akiyama, Masashi; Ihn, Hironobu; Fukushima, Satoshi; Nakamura, Yusuke;


A case of Kindler syndrome with severe esophageal stenosis
INTERNATIONAL JOURNAL OF DERMATOLOGY,54(4):E106-E108 2015(Apr.)
Author:Ohashi, Atsuko; Kiniwa, Yukiko; Okuyama, Ryuhei; Kosho, Tomoki; Suga, Tomoaki; Has, Cristina; Kubo, Hitomi;


A nonsense nucleotide substitution in the oculocutaneous albinism II gene underlies the original pink-eyed dilution allele (Oca2p) in mice. Exp Anim.
Exp Anim.,Epub ahead of print:Epub ahead of print 2015(Jan. 22)
Author:Shoji H, Kiniwa Y, Okuyama R, Yang M, Higuchi K, Mori M.


Identification of DRG-1 As a Melanoma-Associated Antigen Recognized by CD4(+) Th1 Cells
PLOS ONE,10(5) 2015
Author:Kiniwa, Yukiko; Li, Jiang; Wang, Mingjun; Sun, Chuang; Lee, Jeffrey E.; Wang, Rong-Fu; Wang, Helen Y.;


5-Hydroxymethylcytosine as a useful marker to differentiate between malignant melanomas and benign melanocytic nevi.
J Dermatol Sci.,73(2):161-3 2014(Feb. 01)
Author:Uchiyama R,Uhara H, Uchiyama A, Ogawa E, Takazawa Y, Ashida A, Koga H, Hayashi K, Kiniwa Y, Okuyama R


IgA/IgG Pemphigus with Infiltration of Neutrophils and Eosinophils in an Ulcerative Colitis Patient.
Acta Derm Venereol,94:in press 2014
Author:Uchiyama R, Ishii N, Arakura F, Kiniwa Y, Nakazawa K, Uhara H, Hashimoto T, Okuyama R.


Generalized pustulosis associated with disseminated Mycobacterium avium infection in a non-AIDS patient.
Eur J Dermatol.,24(3):402-3 2014
Author:Asai Y, Kiniwa Y, Okada N, Futatsugi T, Ushiki A, Uhara H, Okuyama R.


抗CTLA-4抗体(ipilimumab)を用いたメラノーマ治療
がん分子標的治療,12(1):23-26 2014
Author:木庭幸子,奥山隆平,


日本人のメラノーマにおける遺伝子変異の特徴と治療への応用.
日本皮膚科学会雑誌,124(13):2477-80 2014
Author:木庭幸子,宇原 久


Toll-like receptor 4 signaling promotes the migration of human melanoma cells.
Tohoku J Exp Med,234:57-65 2014
Author:Takazawa Y, Kiniwa Y, Ogawa E, Uchiyama A, Ashida A, Uhara H, Goto Y, Okuyama R.


悪性黒色腫の治療(10)分子標的薬 3)抗体療法
日本臨床,,71(増4):397-401 2013(Aug.)
Author:木庭幸子


悪性黒色腫の治療(9)免疫療法 2)ワクチン療法
日本臨床,71(増4):378-382 2013(Aug.)
Author:木庭幸子


悪性黒色腫の浸潤・転移(2)浸潤・転移に関連する非免疫機序
日本臨床,71(増4):171-175 2013(Aug.)
Author:木庭幸子


NRAS mutations in primary and metastatic melanomas of Japanese patients.
Int J Clin Oncol,.:. 2013(Jun. 06)
Author:Uhara H, Ashida A, Koga H, Ogawa E, Uchiyama A, Uchiyama R, Hayashi K, Kiniwa Y, Okuyama R.,


Low p53 positivity in verrucous skin lesion in diabetic neuropathy occurring on the dorsum of the foot.
Int J Dermatol,52(3):378-80 2013(Mar.)
Author:Ashida A, Kiniwa Y, Kobayashi A, Okuyama R


悪性黒色腫の抗体治療
日本臨床,70(12):2172-76 2012(Dec. 01)
Author:木庭幸子、奥山隆平


非腫瘍性疾患の分子標的薬 アトピー性皮膚炎
日本臨床,70(増刊号):555-60 2012(Nov. 20)
Author:木庭幸子、奥山隆平


Assessment of BRAF and KIT mutations
J Dermatological Science,66:240-242 2012(Apr. 01)
Author:Atsuko Ashida, Hisashi Uhara, Yukiko Kiniwa, Misae Oguchi, Hiroshi Murata, Yasufumi Goto, Aya Uchiyama, Eisaku Ogawa, Koichi Hayashi, Hiroshi Koga, Ryuhei Okuyama


Mutation analysis of BRAF and KIT in circulating melanoma cells at the single cell level
British J Cancer,106:939-46 2012(Feb. 01)
Author:Sakaizawa K, Goto Y, Kiniwa Y, Uchiyama A, Harada K, Shimada S, Saida T, Ferrone S, Takata M, Uhara H, Okuyama R.


A case of epidermolysis bullosa acquisitaassociated with laryngeal stenosis.
Acta Derm Venereol,92:93-94 2012(Jan. 15)
Author:Kiniwa Y, Ashida A, Ohashi A, Kitoh R, Fukuda S, Hashimoto T, Okuyama R.


A case of angiosarcoma arising on a closed shunt in a patient with chronic renal failure.
J Am Acad Dermatol,65(4):882-883 2011(Apr.)
Author:Kamijo F, Kiniwa Y, Goto Y, Tanaka A, Kobayashi A, Shirota S, Fukuzawa M, Saida S


Thermal Angioedema Induced by Hot Water
Acta Derm Veneneol,91(3):343-344 2011(Mar.)
Author:Kobayashi A, Uhara H, Ashida A, Kiniwa Y, Okuyama R


A case of systemic anaplastic large cell lymphoma with “Hodgkin-like” appearance and skin involvement mimicking lymphomatoid papulosis.
J Cutan Pathol,,8(1):38-42 2011
Author:Kiniwa Y, Ide Y, Fukushima M,Asano N, Saida T


メラノーマの免疫療法 ー最近の動向ー
癌と化学療法,37(4):629-633 2010
Author:木庭幸子


NADPH oxidase 4 contributes to transformation phenotype of melanoma cells by regulating G2-M cell cycle progression
Cancer Res,69(6):2647-54 2009
Author:YamauraM, MitsushitaJ, Furuta, S, Kiniwa Y,Ashida A, Goto Y, Shang W. H, Kubodera M, Kato M, Takata M, Saida T,Kamata T,


Tumor-infiltrating gammadelta T cells suppress T and dendritic cell function via mechanisms controlled by a unique toll-like receptor signaling pathway.
Immunity,27(2):334-348 2007
Author:Peng G, Wang HY, Peng W, Kiniwa Y , Seo KH , Wang RF


CD8+ Foxp3+ regulatory T cells mediate immune suppression in prostate cancer
Clin Cancer Res,13(23):6947-58 2007
Author:Kiniwa Y, Wang HY, Peng W, Peng G, Wheeler T, Thompson T, Wang RF


Toll-like receptor 8-mediated reversal of CD4+ regulatory T cell function.
Science.,309:1380-1384 2005
Author:Peng G, Guo Z, Kiniwa Y, Voo KS, Peng W, Fu T, Wang DY, Li Y, Wang HY, Wang RF


Identification of bladder cancer antigens recognized by IgG antibodies of a patient with metastatic bladder cancer
Int J Cancer,108(5):712-724 2004
Author:Ito K, Fujita T, Akada M, Kiniwa Y, Tsukamoto M, Yamamoto A, Matsuzaki Y, Matsushita M, Asano T, Nakashima J, Tachibana M, Hayakawa M, Ikeda H, Murai M, Kawakami Y


Tumor-specific human CD4+ regulatory T cells and their ligands: implications for immunotherapy
Immunity,20(1):107-118 2004
Author:Wang HY, Lee DA, Peng G, Guo Z, Li Y, Kiniwa Y, Shevach EM, Wang RF


Tumor antigens isolated from a patient with vitiligo and T-cell-infiltrated melanoma
CANCER RESEARCH,61(21):7900-7907 2001
Author:Kiniwa, Y; Fujita, T; Akada, M; Ito, K; Shofuda, T; Suzuki, Y; Yamamoto, A; Saida, T; Kawakami, Y

特許等知的財産
登録済特許
ヒト悪性黒色腫抗原
抗癌剤投与効果予測方法
研究費
科学研究費補助金(研究代表者)
2020 - 2022 , 循環腫瘍細胞を用いたメラノーマに対するプレシジョン医療の開発 , 科研費 基盤研究(C)
2016 - 2018 , 悪性黒色腫の循環腫瘍細胞を用いた個別化医療の開発と耐性機序の解明 , 基盤C一般
2013 - 2015 , Notchシグナルがメラノーマで果たす役割の解明と治療への応用 , 基盤研究(C)
2009 - 2011 , メラノーマにおける制御性T細胞誘導へのケモカインと腫瘍浸潤マクロファージの関与 , 基盤研究(C)
2007 - 2008 , ヒトメラノーマにおける腫瘍拒絶能と制御性T細胞による腫瘍エスケープ機構の解明 , 基盤研究(C)

科学研究費補助金(研究分担者)
2008 - 2011 , 創薬化を目指したglypican-3由来がんペプチドワクチン療法のエビデンス創出のための臨床試験エビデンス創出のための臨床試験創薬化を目指したglypican-3由来がんペプチドワクチン療法のエビデンス創出のための臨床試験創薬化を目指したglypican-3由来がんペプチドワクチン療法のエビデンス創出のための臨床試験 , 厚生労働科学研究費補助金

その他公的資金
2016 - 2019 , AMED次世代がん医療創生研究事業

その他
- 2008 , ヒトメラノーマにおける癌幹細胞の同定
- 2008 , メラノーマにおける抗原特異的な制御性リンパ球の解析
- 2007 , 悪性黒色腫における癌幹細胞の同定

教育活動実績

授業等
2021 , 前期 , 皮膚科学
2020 , 通年 , 臨床腫瘍学

社会活動実績

社会活動等
公開講座
2019.3. - , 信州アレルギー市民フォーラム2019
2018.2. - , 信州アレルギー市民フォーラム2018
2017.2. - , 信州アレルギー市民フォーラム2017
2012.2. - , 信州アレルギー市民フォーラム2012
2011.2. - , 信州アレルギー市民公開講座

メディア・報道
20190727 , 長野放送 , 健康ばんざい「じんましん」
20190423 , 信濃毎日新聞 MGプレス , 紫外線対策