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Izawa Atsushi

Academic OrganizationAcademic Assembly School of Medicine and Health Sciences Institute of Health ScienceTEL
Education and Research OrganizationSchool of Medicine Department of Adult and Geriatric NursingFAX
PositionProfessorMail Address
AddressWeb site


Research Field
Academic Background
Graduate School

2006 , International Young Investigator's Award
2005 , International Young Investigator's Award
2004 , Domestic Young Investigator's Award


Books, Articles, etc.
中外医学社 , 心不全診療Q&A エキスパ–ト106人からの回答 2012
Author:山崎佐枝子、伊澤 淳、池田宇一

中外医学社 , 心不全診療Q&A エキスパ–ト106人からの回答 , :211-212 2012
Author:小塚綾子、伊澤 淳、池田宇一

Heart View , 16:110-115 2012
Author:伊澤 淳

Electrical Stormによる心原性ショックに対し低用量ランジオロール塩酸塩が奏効した心筋梗塞の若年例
日本心臓病学会誌 , 7(3):226-232 2012
Author:南澤匡俊、相澤万象、伊澤 淳、矢口智規、佐藤俊夫、三枝達也、越川めぐみ、笠井宏樹、富田 威、宮下裕介、熊崎節央、小山 潤、池田宇一

心臓 , 44(9):1188-1194 2012
Author:小口泰尚、伊澤 淳、小田切久八、元木博彦、富田 威、宮下裕介、熊崎節央、小山 潤、今村 浩、岡元和文、矢崎善一、池田宇一

心臓リハビリテーション(JJCR) , 17(2):233-237 2012
Author:山崎佐枝子、高橋友明、内田 緑、伊澤 淳、池田宇一

Assessment of Depressive Tendency, Coping Strategies, and Type D Personality in Japanese Patients with Coronary Artery Disease
信州医学雑誌,68(2):97-105 2020(Apr.)
Author:Yamaguchi D, Izawa A, Matsunaga Y

脳心血管病の現状と課題超高齢社会における健康長寿のための保健医療: 先制予防医療の可能性
信州医学雑誌,66(5):307-318 2018(Oct.)

Initial Experience of Percutaneous Extraction of Infected Cardiac Implantable Electric Devices Using Excimer Laser
信州医学雑誌,63(2):103-108 2015(Apr. 10)
Author:OKADA, Ayako; IZAWA, Atsushi; MOTOKI, Hirohiko; TOMITA, Takeshi; MIYASHITA, Yusuke; KOYAMA, Jun; AIZAWA, Kazunori; SHODA, Morio; IKEDA, Uichi

Left ventricular deformation and torsion assessed by speckle-tracking echocardiography in patients with mutated transthyretin-associated cardiac amyloidosis and the effect of diflunisal on myocardial function.
IJC Heart&Vasculature,9:1-10 2015
Author:Koyama J,Minamisawa M,Sakijima Y,Ikeda S,Kozuka Aebisawa S,Miura T,Motoki H,Okada A,Izawa A,Ikeda U.

Impact of combonation therapy with statin and ezetimibe on secondart prevention for post-acute myocardial infaction patients in the stain era.
IJC Heart&Vasculature,8:154-160 2015
Author:Ebisawa S,Izawa A,Ueki Y,Hioki H,Minamizawa M,Hashizume N,Abe N,Kashima Y,Miura T,Takeuchi T,Motoki H,Okada A,Miyashita Y,Koyama J,Ikeda U,

Clinical Impact of rapid Reduction of Low-Density Lipoprotein Cholesterol Level on Long-Term Outcome of Acute Myocardial Infarction in the Stain Era:Subanalysis of the ALPS-AMIstudy.
PLoS One,10(6):e0127835 2015
Author:Miura T,Izawa A,Motoki H,Miyashita Y,Kashima Y,Ebisawa S,Tomita T,Koyam J,Ikeda U.

Prognostic significance of neuroadrenergic dysfunction for cardiovascular events in patients with acute myocardial infaction.
Circ J,79(10):2238-2245 2015
Author:Minamisawa M,Izawa A,Motoki H,Kashima Y,Hioki H,Abe N,Miura T,Ebisawa S,Miyashita Y,Koyama J,Ikeda U.

Associationbetweenestimatedglomerularfiltrationrateandperipheralarterial disease.
J Cardiology,66(5):430-434 2015
Author:Yamasaki S, Izawa A,Koshikawa M,Saigusa T,Ebisawa S,Miura T, Shiba Y, Tomita T, Miyashita Y, Koyama J, Ikeda U.

Transplantation of adipose tissue-derived stem cells improvescardiac contractile function and electrical stability in a rat myocardial infarction model.
J Mol Cell Cardiol,81:139-149 2015
Author:Gautam M,Fujita D,Kimura K,Ichikawa H,Izawa A,Hirose M,Kashihara T,Yamada M,Takahashi M,Ikeda U.

Intital exprerience of percutaneous extracyion of infected cardiac implantable electricdevices using excimer laser.
shinshu med J,63(2):103-108 2015
Author:Okada A,Izawa A,Motoki H,Tomita T,Miyashita Y,Koyama J,Aizawa K,Shoda M,Ikeda U.

A young patient with atypical type-B Wolff-Parkinson-White syndrome accompanied by ieft ventricular dysfunction.
J Arrhythm,31(1):50-54 2015
Author:Takeuchi T,Tomita T,Kasai H,Kashiwagi D,Yoshie K,Yaguchi T,Oguchi Y,Kozuka A,Gautam M,Motoki H,Okada A,Shiba Y,Aizawa K,Izawa A,Miyashita Y,Koyama J,Hongo M,Ikeda U.

Prognostic improvement by multidisciplinary therapy in patients wiyh criticak limb ischemia.
Angiology,66(2):187-194 2015
Author:Hioki H,Miyashita Y,Miura T,Ebisawa S,Motoki H,Izawa A,Tomita T,Koyama J,Ikeda U,

Electrocardiographic j waves are associated with right ventricular morphology and function:evalution by cardiac magnetic resonance imaging.
Heart Vessels,30(1):98-107 2015
Author:Takeuchi T,Tomita T,Yoshie K,Hioki H,Oguchi Y,Miura T,Ebisawa S,Motoki H,Okada A,Aizawa K,Izawa A,Miyashita Y,Koyama J,Ikeda U.

A2-year follow-up of oxidative stress levels in patients wiyh ST-segment elevation myocaldial infarction:Asubanaysis of the ALPS-AMI study.
Angiology,66(3):271-277 2015
Author:Abe N,Kashima Y.Izawa A,,Motoki H,Ebisawa S,Miyashita Y,Imamura H,Ikeda U.

Assessmentof Lipophilic vs.Hydrophilic Statin Therapy in Acute Myocardial Infarction.
Circ J,79(1):161-168 2015
Author:Izawa A,Kashima Y,Miura T,Ebisawa S,Yamamoto H,Sakurai S,Kagoshima M,Tomita T,Miyashita Y,Koyama J,Ikeda U.

Importance of fatty acid compositions in patients with peripheral arterial disease.
PLoS One,9(9):e107003 2014
Author:Gautam M, Izawa A, Shiba Y, Motoki H, Takeuchi T, Okada A, Tomita T, Miyashita Y, Koyama J, Ikeda U.

Significant pericardial involvement of immunoglobulin g4-related disease.
Ann Thorac Surg.,98(2):e47-e49 2014
Author:Morita T, Izawa A, Hamano H, Asano N, Kozuka A, Motoki H, Fuke M, Koyama J, Amano J, Ikeda U.

Diagonostic value of peripheral fractional flow reserve in isolated lliac artery stenosis : A comparison with the post-exercise ankle-brachial index.
J Endovasc Ther,21(5):625-632 2014
Author:Hioki H, Miyashita Y, Miura T, Ebisawa S, Motoki H, Izawa A, Tomita T, Koyama J, Ikeda U.

Impact of azelnidipine and amlodipine on left ventricular mass and longitudinal function in hypertensive patients with left ventricular hypertrophy.
Echocardiography,31(10):1230-1238 2014
Author:Motoki H, Koyama J, Izawa A, Tomita T, Miyashita Y, Takahashi M, Ikeda U.

Impact of endovascular therapy on oxidative stress in patients with peripheral artery disease.
Circ J,78(6):1445-1450 2014
Author:Ebisawa S, Kashima Y, Miyashita Y, Yamazaki S, Abe N, Saigusa T, Miura T, Motoki H, Izawa A, Ikeda U.

Infective endocarditis associated with mitral valve prolapse in a patient with klinefelter syndrome.
Intern Med,53(9):969-972 2014
Author:Ueki Y, Izawa A, Ebisawa S, Motoki H, Miyashita Y, Tomita T, Koyama J, Takano T, Amano J, Ikeda U.

In-hospital clinical outcomes of elderly patients (≥80 Years) undergoing percutaneous coronary intervention.
Circ J,78(5):1097-1103 2014
Author:Miura T, Miyashita Y, Motoki H, Shimada K, Kobayashi M, Nakajima H, Kimura H, Akanuma H, Mawatari E, Sato T, Hotta S, Kamiyoshi Y, Maruyama T, Watanabe N, Eisawa T, Aso S, Uchikawa S, Hashizume N, Sekimura N, Morita T, Ebisawa S, Izawa A, Tomita T, Koyama J, Ikeda U.

The traditional japanese medicine (Kampo) boiogito has a dual benefit in cardiorenal syndrome: A pilot observational study.
Shinshu Med J,62(2):89-97 2014
Author:Gautam M, Izawa A, Saigusa T, Yamasaki S, Motoki H, Tomita T, Miyashita Y, Koyama J, Hongo M, Ikeda U.

Low levels of high-density lipoprotein cholesterol predict the presence of coronary artery disease in patients with aortic aneurysms.
Angiology,65(8):710-715 2014
Author:Saigusa T, Izawa A, Miura T, Ebisawa S, Shiba Y, Miyashita Y, Tomita T, Koyama J, Fukui D, Takano T, Amano J, Ikeda U.

Infective Endocarditis Associated with Mitral Valve Prolapse in a Patient with Klinefelter Syndrome
INTERNAL MEDICINE,53(9):969-972 2014
Author:Ueki, Y; Izawa, A; Ebisawa, S; Motoki, H; Miyashita, Y; Tomita, T; Koyama, J; Takano, T; Amano, J; Ikeda, U

Serum high-density lipoprotein cholesterol level and lifestyle habits among japanese junior high school students.
Shinshu Med J,61(4):205-215 2013
Author:Hongo M, Hidaka H, Sakaguchi S, Nakanishi K, Terasawa F, Ichikawa M, Hirota N, Tsuruta G, Tanaka N, Izawa A, Yazaki Y, Ikeda U, Koike K, on behalf of the Investigators of the Study Project on Prevention of Metabolic Syndrome among Children, Adolescents, and Young Adults in Shinshu.

Peak systolic velocity of pulmonary venous flow and mitral annulus are independent predictors of left ventricular global longitudinal strain in patients with cardiomyopathy.
Int J Cardiol,168(6):5462-5464 2013
Author:Koyama J, Kozuka A, Minamisawa M, Motoki H, Izawa A, Tomita T, Miyashita Y, Takahashi M, Ikeda U.

Crucial role of hyaluronan in neointimal formation after vascular injury.
PLoS One,8(3):e58760 2013
Author:Kashima Y, Takahashi M, Shiba Y, Itano N, Izawa A, Koyama J, Nakayama J, Taniguchi S, Kimata K, Ikeda U.

Critical in-stent restenosis following fracture of biolimus-eluting stent: a report of 2 cases.
J Invasive Cardiol,25(1):E11-E13 2013
Author:Hioki H, Kumazaki S, Izawa A.

Presence of diastolic dysfunction in patients with peripheral artery disease.
Angiology,64(7):540-543 2013
Author:Yamasaki S, Izawa A, Shiba Y, Tomita T, Miyashita Y, Koyama J, Ikeda U.

High concentrations of omega-3 fatty acids are associated with the development of atrial fibrillation in the Japanese population
HEART AND VESSELS,28(4):497-504 2013
Author:Tomita, T; Hata, T; Takeuchi, T; Oguchi, Y; Okada, A; Aizawa, K; Koshikawa, M; Otagiri, K; Motoki, H; Kasai, H; Izawa, A; Koyama, J; Hongo, M; Ikeda, U

Immunoadsorption therapy reduces oxidative stress in patients with dilated cardiomyopathy
World Journal of Cardiovascular Diseases,2:305-312 2012
Author:Kasai H, Kashima Y, Izawa A, Tomita T, Miyashita Y, Koyama J, Takahashi M, Yoshio T, Yazaki Y, Higuchi M, Ikeda U

Torsion analysis in the early detection of anthracycline-mediated cardiomyopathy
Eur Heart J Cardiovasc Imaging,13(1):95-103 2012
Author:Motoki H, Koyama J, Nakazawa H, Aizawa K, Kasai H, Izawa A, Tomita T, Miyashita Y, Kumazaki S, Takahashi M, Ikeda U

Hemodialysis-induced P-wave signal-averaged electrocardiogram alterations are indicative of vulnerability to atrial arrhythmias
Circ J,76(3):612-617 2012
Author:Shimada K, Tomita T, Kamijo Y, Higuchi M, Ito K, Koizumi Y, Yamamoto K, Aizawa K, Koshikawa M, Kasai H, Izawa A, Miyashita Y, Kumazaki S, Koyama J, Ikeda U

Catheter ablation of non-inducible atrial tachycardia after surgical repair of heart disease
Heart Vessels,27(1):114-118 2012
Author:Tomita T, Aizawa K, Takeuchi T, Shimada K, Okada A, Koshikawa M, Kasai H, Izawa A, Miyashita Y, Kumazaki S, Koyama J, Ikeda U.

大動脈疾患における降圧薬(わかりやすい血管疾患と薬物療法 第5回)
Vascular Lab,8(5):539-541 2011

Heart View,15:816-820 2011

Therapeutic Research,32(10):1241-1244 2011
Author:相澤万象、宮下裕介、富田 威、越川めぐみ、笠井宏樹、伊澤 淳、熊崎節央、小山 潤、池田宇一

日本臨床,69(増刊7):510-514 2011

血栓と循環,19(1):67-70 2011

Low-dose rosuvastatin improves arterial stiffness in high-risk Japanese patients with dyslipdemia in a primary prevention group.
Circ J,75(11):2660-2667 2011
Author:Hongo M, Kumazaki S, Izawa A, Hidaka H, Tomita T, Yazaki Y, Kinoshita O, Ikeda U

Successful Treatment of Cardiac Diffuse Large B-cellLymphoma: A Report of two Cases.
Shinshu Med J,59(3):177-183 2011
Author:Kumazaki S, Izawa A, Minamisawa M, Ishida F, Sano K, Uehara T, Kasai H, Tomita T, Miyashita Y, Koyama J, Ikeda U.

Influence of circumferential pulmonary vein isolation for atrial fibrillation on ST elevation in patient with Brugada syndrome.
Int J Cardiol,149:e82-e84 2011
Author:Tomita T, Aizawa K, Shimada K, Motoki H, Otagiri K, Koshikawa M, Kasai H, Izawa A, Kumazaki S, Tsutsui H, Koyama J, Ikeda U.

Critical role of Th17 cells in inflammation and neovascularization after ischaemia.
Cardiovasc Res,90(2):364-372 2011
Author:Hata T, Takahashi M, Hida S, Kawaguchi M, Kashima Y, Usui F, Morimoto H, Nishiyama A, Izawa A, Koyama J, Iwakura Y, Taki S, Ikeda U.

Inflammasome activation of cardiac fibroblasts is essential for myocardial ischemia/reperfusion injury.
Circulation,123(6):594-604 2011
Author:Kawaguchi M, Takahashi M, Hata T, Kashima Y, Usui F, Morimoto H, Izawa A, Takahashi Y, Masumoto J, Koyama J, Hongo M, Noda T, Nakayama J, Sagara J, Taniguchi S, Ikeda U.

Transient pseudorestrictive pattern of transmitral flow velocity curve in patients with paroxysmal atrial ibrillation.
Echocardiography,28(3):289-297 2011
Author:Motoki H, Koyama J, Tomita T, Aizawa K, Kasai H, Koshikawa M, Izawa A, Kumazaki S, Takahashi M, Ikeda U.

Early Intervention with Rosuvastation Decreases the Lipid Components of the Plaque in Acute Coronary Syndrome.
Circ J,75(3):633-641 2011
Author:Otagiri K, Tsutsui H, Kumazaki S, Miyashita Y, Aizawa K, Koshikawa M, Kasai H, Izawa A, Tomita T, Koyama J, Ikeda U.

A novel in vivo regulatoryrole of P-glycoprotein in alloimmunity.
Biochem Biophys Res Commun.,394(3):646-652 2010
Author:Izawa A, Schatton T, Frank NY, Ueno T, Yamaura K, Pendse SS, Margaryan A, Grimm M, Gasser M, Waaga-Gasser AM, Sayegh MH, Frank MH.

Effect of graft adaptation of the internal mammary artery on longitudinal phasic blood flow velocity characteristics after surgery.
Heart Vessels,25:515-521 2010
Author:Kumazaki S, Koyama J, Aizawa K, Kasai H, Koshikawa M, Izawa A, Tomita T, Takahashi M, Ikeda U.

A case of left atrial involvement of cardiac sarcoidosis manifesting as atrial flutter treated with corticosteroids.
Journal of Cardiology Cases,1(2):e71-e74 2010
Author:Aso S, Izawa A, Abe N, Motoki H, Kasai H, Tomita T, Kumazaki S, Koyama J, Yazaki Y, Ikeda U.

Dynamic left ventricular outflow tract obstruction due to anemia in a 71-year-old patient with sigmoid septum.
Journal of Cardiology Cases,1(3):e144-e146 2010
Author:Hioki H, Izawa A, Miura T, Motoki H, Aizawa K, Koshikawa M, Kasai H, Tomita T, Miyashita Y, Kumazaki S, Koyama J, Ikeda U.

Coagulation Activity is Increased in the Left Atria of Patients With Paroxysmal Atrial Fibrillation During the Non-Paroxysmal Period - Comparison With Chronic Atrial Fibrillation -
CIRCULATION JOURNAL,73(8):1403-1407 2009(Aug.)
Author:Motoki, Hirohiko; Tomita, Takeshi; Aizawa, Kazunori; Kasai, Hiroki; Izawa, Atsushi; Kumazaki, Setsuo; Tsutsui, Hiroshi; Koyama, Jun; Ikeda, Uichi

Therapeutic neovascularization by the implantation of autologous mononuclear cells in patients with connective tissue diseases.
Curr Pharm Design,15:2778-2783 2009
Author:Takahashi M, Izawa A, Ishigatsubo Y, Fujimoto K, Miyamoto M, Horie T, Aizawa Y, Amano J, Minota S, Murohara T, Matsubara H, Ikeda U.

Rationale and design of assessment of Lipophilic vs. hydrophilic statin therapy in acute myocardial infarction (the ALPS-AMI) study.
J Cardiology,54:76-79 2009
Author:Kashima Y, Izawa A, Aizawa K, Koshikawa M, Kasai H, Tomita T, Kumazaki S, Tsutsui H, Koyama J, Ikeda U.

Noninvasive Evaluation of Coronary Endothelial Function following Sirolimus-Eluting Stent Implantation by Using Positron Emission Tomography.
Cardiology,114:157-163 2009
Author:Horigome M, Kumazaki S, Hattori N, Kasai H, Horigome M, Aizawa K, Izawa A,Tomita T, Tsutsui H, Koyama J, Sakurai S, Ikeda U.

Coagulation Activity is Increased in the Left Atria of Patients with Paroxysmal Atrial Fibrillation During the Non-Paroxysmal Period ― Comparison with Chronic Atrial Fibrillation―.
Circ J,73:1403-1407 2009
Author:Motoki H, Tomita T, Aizawa K, Kasai H, Izawa A, Kumazaki S, Tsutsui H, Koyama J, Ikeda U.

Elevated osteopontin levels in patients with peripheral arterial disease.
Angiology,60:42-45 2009
Author:Koshikawa M, Aizawa K, Kasai H, Izawa A, Tomita T, Kumazaki S, Tsutsui H, Koyama J, Shimodaira S, Takahashi M, Ikeda U.

Immunoadsorption therapy for patients with dilated cardiomyopathy and heart failure.
Current Cardiology Reviews,4:219-222 2008
Author:Ikeda U, Kasai H, Izawa A, Koyama J, Yazaki Y, Higuchi M, Chang-Sung Koh, Yamamoto K.

Risk stratification assessed by combined lung and heart iodine-123 metaiodobenzylguanidine uptake in patients with idiopathic dilated cardiomyopathy.
Am J Cardiol.,101:1482-1486 2008
Author:Kamiyoshi Y, Yazaki Y, Urushibata K, Koizumu T, Kasai H, Izawa A, Kinoshita O, Hongo M, Ikeda U.

M-CSF accelerates neointimal formation in the early phase after vascular injury in mice: the critical role of the SDF-1-CXCR4 system.
Arterioscler Thromb Vasc Biol,27:283-289 2007
Author:Shiba Y, Takahashi M, Yoshioka T, Yajima N, Morimoto H, Izawa A, Ise H, Hatake K, Motoyoshi K, Ikeda U.

Erythropoietin attenuates the development of experimental autoimmune myocarditis.
Cardiovasc Drug Ther,21:17-27 2007
Author:Hirose S, Takahashi M, Ogawa R, Morimoto H, Izawa A, Sato H, Ise H, Hongo M, Ikeda U.

Bone marrow-derived CXCR4+ cells mobilized by M-CSF participate in the prevention of cardiac dysfunction and remodeling after myocardial infarction in mice.
Am J Pathol,171:755-766 2007
Author:Morimoto H, Takahashi M, Shiba Y, Izawa A, Ise H, Hongo M, Hatake K, Motoyoshi K, Ikeda U.

Effective uptake of N-acetylglucosamine-conjugated liposome by cardiomyocytes in vitro.
J Control Release,122:189-198 2007
Author:Aso S, Ise H, Takahashi M, Kobayashi S, Morimoto H, Izawa A, Goto M, Ikeda U.

Importance of Donor- and Recipient-Derived Selectins in Cardiac Allograft Rejection.
J Am Soc Nephrol,18:2929-2936 2007
Author:Izawa A, Ueno T, Jurewicz M, Ito T, Tanaka K, Takahashi M, Ikeda U, Sobolev O, Fiorina P, Smith RN, Hynes RO, Abdi R.

Cre/loxP-mediated CTLA4IgG gene transfer induces clinically relevant immunosuppression via on-off gene recombination in vivo
Author:Izawa, A; Sano, K; Takehara, M; Inobe, M; Suzuki, J; Imamura, H; Takahashi, M; Ikeda, U; Isobe, M; Uede, T

Changes in cardiac lipid metabolism during sepsis: The essential role of very low-density lipoprotein receptors
Author:Jia, LJ; Takahashi, M; Morimoto, H; Takahashi, S; Izawa, A; Ise, H; Iwasaki, T; Hattori, H; Wu, KJ; Ikeda, U

Collagen synthesis is required for ascorbic acid-enhanced differentiation of mouse embryonic stem cells into cardiomyocytes
Author:Sato,H; Takahashi, M; Ise, H; Yamada, A; Hirose, S; Tagawa, Y; Morimoto, H; Izawa, A; Ikeda, U

Efficacy of mycophenolic acid combined with KRP-203, a novel immunomodulator, in a rat heart transplantation model
Author:Suzuki, C; Takahashi, M; Morimoto, H; Izawa, A; Ise, H; Fujishiro, J; Murakami, T; Ishiyama, J; Nakada, A; Nakayama, J; Shimada, K; Ikeda, U; Kobayashi, E

Granulocyte colony-stimulating factor (G-CSF) accelerates reendothelialization and reduces neointimal formation after vascular injury in mice
Author:Yoshioka, T; Takahashi, M; Shiba, Y; Suzuki, C; Morimoto, H; Izawa, A; Ise, H; Ikeda, U

Mycophenolate mofetil attenuates pulmonary arterial hypertension in rats
Author:Suzuki, C; Takahashi, M; Morimoto, H; Izawa, A; Ise, H; Hongo, M; Hoshikawa, Y; Ito, T; Miyashita, H; Kobayashi, E; Shimada, K; Ikeda, U

Cardiac overexpression of monocyte chemoattractant protein-1 in transgenic mice prevents cardiac dysfunction and remodeling after myocardial infarction
CIRCULATION RESEARCH,99(8):891-899 2006
Author:Morimoto, H; Takahashi, M; Izawa, A; Ise, H; Hongo, M; Kolattukudy, PE; Ikeda, U

Drug delivery system targeting the injured myocardium
CIRCULATION,114(18):211-211 2006
Author:Aso, S; Ise, H; Takahashi, M; Kobayashi, S; Morimoto, H; Izawa, A; Ikeda, U

Role of cardiac MCP-1 in murine myocardial infarction model
Author:Morimoto, H; Takahashi, M; Ise, H; Izawa, A; Hongo, M; Kolattukudy, PE; Ikeda, U

A critical increase in right-to-left shunt after acute myocardial infarction in a 68-year-old male with tetralogy of Fallot
Author:Izawa, A; Sekimura, N; Uchikawa, S; Yazaki, Y; Kinoshita, O; Owa, M; Kubo, K; Ikeda, U; Sekiguchi, M; Kitahara, H; Amano, J; Imamura, H

Dietary consumption of green tea catechins attenuate hyperlipidaemia-induced atherosclerosis and systemic organ damage in mice
ACTA CARDIOLOGICA,60(3):271-276 2005
Author:Suzuki, J; Ogawa, M; Izawa, A; Sagesaka, YM; Isobe, M

Continuous positive airway pressure therapy prevents arrhythmias in patients with sleep apnea syndrome
CIRCULATION,112(17):U765-U765 2005
Author:Abe, H; Takahashi, M; Ise, H; Izawa, A; Morimoto, H; Yamazaki, K; Kamikozawa, M; Yaegashi, H; Eda, S; Kinoshita, O; Ikeda, U

Downregulation of very low-density lipoprotein receptor by interleukin-1 beta in vascular smooth muscle cells: Possible link between inflammatory cytokines and lipid metabolism
CIRCULATION,112(17):U342-U342 2005
Author:Takahashi, M; Takahashi, S; Suzuki, C; Jia, LJ; Morimoto, H; Izawa, A; Ise, H; Hattori, H; Ikeda, U

Development of a novel drug delivery system for the infarcted myocardium using putative glycoside-binding protein
CIRCULATION,112(17):U250-U250 2005
Author:Ise, H; Takahashi, M; Morimoto, H; Izawa, A; Maruyama, A; Ikeda, U

Effect of macrophage colony-stimulating factor (M-CSF) on recruitment of bone marrow-derived cells and neointimal formation after vascular injury in mice
CIRCULATION,112(17):U219-U219 2005
Author:Shiba, Y; Takahashi, M; Yoshioka, T; Yajima, N; Izawa, A; Morimoto, H; Ise, H; Kinoshita, O; Ikeda, U; Hatake, K; Motoyoshi, K

Granulocyte colony-stimulating factor treatment accelerates reendothelialization and decreases neointimal formation after vascular injury in mice
Author:Yoshioka, T; Takahashi, M; Shiba, Y; Suzuki, C; Morimoto, H; Izawa, A; Ise, H; Ikeda, U

Trends over the last 20 years in the clinical background of young Japanese patients with coronary artery disease
CIRCULATION JOURNAL,68(3):186-191 2004
Author:Imamura, H; Izawa, A; Kai, R; Yokoseki, O; Uchikawa, SI; Yazaki, Y; Kinoshita,O; Hongo, M; Kubo, K

Anti-vascular cell adhesion molecule-1 and anti-very late antigen-4 monoclonal antibodies inhibit neointimal hyperplasia in the murine model of arterial injury
ACTA CARDIOLOGICA,59(2):147-152 2004
Author:Suzuki, J; Izawa, A; Isobe, M

Percutaneous cardiopulmonary support aids resuscitation from sustained ventricular tachycardia
CIRCULATION JOURNAL,67(12):1061-1063 2003
Author:Izawa, A; Kinoshita, O; Shiba, Y; Takahashi, W; Uchikawa, S; Imamura, H; Owa, M; Kubo, K

Tranilast inhibits cardiac allograft vasculopathy in association with p21(Waf1/Cip1) expression on neointimal cells in murine cardiac transplantation model
Author:Izawa, A; Suzuki, J; Takahashi, W; Amano, J; Isobe, M

Successful prevention of recurrent ventricular fibrillation by intravenous isoproterenol in a patient with Brugada syndrome
Author:Tanaka, H; Kinoshita, O; Uchikawa, S; Kasai, H; Nakamura, M; Izawa, A; Yokoseki, O; Kitabayashi, H; Takahashi, W; Yazaki, Y; Watanabe, N; Imamura, H; Kubo, K

Two cases of bronchial asthma after treatment with amiodarone
Author:Imamura, H; Kinoshita, O; Maruyama, K; Izawa, A; Uchikawa, SI; Kumazaki, S; Takahashi, W; Yokoseki, O; Yazaki, Y; Koizumi, T; Kubo, K

Transient left ventricular aneurysm and hypertrophy accompanied by polymorphic ventricular tachycardia in a patient suspected of acute myocarditis
JAPANESE HEART JOURNAL,41(1):97-102 2000
Author:Izawa, A; Yazaki, Y; Hayashi, S; Imamura, H; Kusama, Y;Isobe, M

Inducible nitric oxide-mediated myocardial apoptosiscontributes to graft failure during acute cardiac allograft rejection in mice
JAPANESE HEART JOURNAL,41(4):493-506 2000
Author:Takahashi, W; Suzuki, J; Izawa, A; Takayama, K; Yamazaki, S; Isobe, M

Gene therapy for attenuating cardiac allograft arteriopathy using ex vivo E2F decoy transfection by HVJ-AVE-liposome method in mice and nonhuman primates
CIRCULATION RESEARCH,87(11):1063-1068 2000
Author:Kawauchi, M; Suzuki, J; Morishita, R; Wada, Y; Izawa, A; Tomita, N; Amano, J; Kaneda, Y; Ogihara, T; Takamoto, S; Isobe, M

Role of natural killer cells in the rejection of transplanted hearts in the mouse model
Author:Hase, T; Yoshimura, R; Wada, S; Wantanabe, Y; Izawa, A; Isobe, M; Kishimoto, T; Chargui, J

Antisense Cdc2 kinase oligonucleotide inhibits adhesion molecule expression in cardiac allograft arteriopathy
Author:Suzuki, J; Izawa, A; Morishita, R; Kaneda, Y; Sawa, Y; Okubo, Y; Ogihara, T; Sekiguchi, M; Isobe, M

Prevention of cardiac allograft arteriopathy by antisense cdc2 kinase oligonucleotide
Author:Suzuki, J; Izawa, A; Morishita, R; Kaneda, Y; Sawa, Y; Okubo, Y; Ogihara, T; Sekiguchi, M; Isobe, M

Differential Th1 and Th2 cell regulation of murine cardiac allograft acceptance by blocking cell adhesion of ICAM-1/LFA-1 and VCAM-1/VLA-4
Author:Suzuki, J; Isobe, M; Izawa, A; Takahashi, W; Yamazaki, S; Okubo, Y; Amano, J; Sekiguchi, M

E2F decoy suppresses E-selectin expression in murine cardiac allograft arteriopathy
Author:Suzuki, J; Isobe, M; Morishita, R; Izawa, A; Yamazaki, S; Okubo,Y; Kaneda, Y; Sekiguchi, M

Research Grants
Grants‐in‐aid for Scientific Research(Research Representative)
2008 - 2010 , 慢性心不全患者における免疫異常と自律神経異常の相互連関に関する研究 , 基盤研究(C)