TAIRA Chiaki
Academic Assembly School of Medicine and Health Sciences Institute of Health Science
School of Medicine Department of Health Sciences Biomedical Laboratory Sciences
Assistant Professor
Researcher Information
Research activity information
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Paper
- Redox index of Cys-thiol residues of serum apolipoprotein E and its diagnostic potential.
Yamauchi K, Taira C, Kawakami Y.
Biosci Rep., 41(8), BSR20211060., 2021 - Novel variant fibrinogen γp.C352R produced hypodysfibrinogenemia leading to a bleeding episode and failure of infertility treatment.
Yoda M, Kaido T, Kamijo T, Taira C, Higuchi Y, Arai S, Okumura N.
Int J Hematol., 114(3), 325-333, 2021 - 心房細動の再発予測：高感度トロポニンTとNT-proBNPの有用性
平 千明、伊澤 淳、岡田綾子、桑原宏一郎、奥村伸生
臨床化学, 50, 135-143, 2021
Lead - フィブリノゲン低下の著しい重症線溶亢進型DICに認められた2つのフィブリノゲン遺伝子変異
依田将宏, 海藤貴大, 上條途夢, 新井慎平, 平 千明, 樋口由美子, 長田 眞, 塚田唯子, 奥村伸生
臨床病理, 68(5), 390-397, May 2020 - Heterozygous variant fibrinogen gamma A289V (Kanazawa III) was confirmed as hypodysfibrinogenemia by plasma and recombinant fibrinogens
Kaido, Takahiro; Yoda, Masahiro; Kamijo, Tomu; Taira, Chiaki; Higuchi, Yumiko; Okumura, Nobuo;
INTERNATIONAL JOURNAL OF LABORATORY HEMATOLOGY, 42(2), 190-197, Apr. 2020
- Comparison of molecular structure and fibrin polymerization between two B beta-chain N-terminal region fibrinogen variants, B beta p.G45C and B beta p.R74C
Kaido, Takahiro; Yoda, Masahiro; Kamijo, Tomu; Taira, Chiaki; Higuchi, Yumiko; Okumura, Nobuo;
INTERNATIONAL JOURNAL OF HEMATOLOGY, 2020 - Complete measurable residual disease response after combination chemotherapy with AML-type and ALL-type regimens in pediatric B/myeloid acute bilineal leukemia
Saito, Shoji; Taira, Chiaki; Matsuda, Kazuyuki; Yanagisawa, Ryu; Morita, Daisuke; Shigemura, Tomonari; Yoshikawa, Kentaro; Tanaka, Miyuki; Sakashita, Kazuo; Mukai, Saki; Shimodaira, Shigetaka; Koike, Kenichi; Nakazawa, Yozo;
LEUKEMIA & LYMPHOMA, 61(4), 967-970, 2020 - gamma D318Y fibrinogen shows no fibrin polymerization due to defective "A-a" and "B-b" interactions, whereas that of gamma K321E fibrinogen is nearly normal
Kamijo, Tomu; Mukai, Saki; Taira, Chiaki; Higuchi, Yumiko; Okumura, Nobuo;
THROMBOSIS RESEARCH, 182, 150-158, Oct. 2019 - 生理系専門科目におけるアクティブ・ラーニングの実践
平 千明、樋口由美子、伊澤 淳、奥村伸生、太田浩良
臨床検査学教育, 11(2), 195-199, 01 Sep. 2019 - FGA 1238bp欠失を有する無フィブリノゲン血症3例のハプロタイプ解析.
平 千明, 竹澤 由夏, 新井 慎平, 松田 和之, 上條 途夢, 樋口 由美子, 奥村 伸生.
医学検査, 2019 - Fibrin monomers derived from thrombogenic dysfibrinogenemia, Naples-type variant (B beta Ala68Thr), showed almost entirely normal polymerization
Kamijo, Tomu; Nagata, Kazuhiro; Taira, Chiaki; Higuchi, Yumiko; Arai, Shinpei; Okumura, Nobuo;
THROMBOSIS RESEARCH, 172, 1-3, Dec. 2018 - Rapid ABO genotyping by high-speed droplet allele-specific PCR using crude samples
Taira, Chiaki; Matsuda, Kazuyuki; Takeichi, Naoya; Furukawa, Satomi; Sugano, Mitsutoshi; Uehara, Takeshi; Okumura, Nobuo; Honda, Takayuki;
JOURNAL OF CLINICAL LABORATORY ANALYSIS, 32(1), Jan. 2018 - フィブリノゲン蓄積病を呈する異常フィブリノゲン産生細胞の繊維状封入体形成と小胞体ストレス応答.
上條 途夢, 大久保 奈緒, 平 千明, 樋口 由美子, 新井 慎平, 奥村 伸生.
臨床病理, 2018 - A Novel Mutation in the Fibrinogen B Chain (c.490G > A; End of Exon 3) Causes a Splicing Abnormality and Ultimately Leads to Congenital Hypofibrinogenemia
Taira, Chiaki; Matsuda, Kazuyuki; Arai, Shinpei; Sugano, Mitsutoshi; Uehara, Takeshi; Okumura, Nobuo;
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 18(11), Nov. 2017 - A novel frameshift mutation in the fibrinogen gamma C terminal region, FGG c. 1169_1170 del AT, leading to hypofibrinogenemia
Nagata, Kazuhiro; Arai, Shinpei; Sugano, Mitsutoshi; Taira, Chiaki; Okumura, Nobuo; Honda, Takayuki;
THROMBOSIS RESEARCH, 159, 82-85, Nov. 2017 - Development of a rapid and sensitive one-step reverse transcription-nested polymerase chain reaction in a single tube using the droplet-polymerase chain reaction machine
Yamaguchi, Akemi; Matsuda, Kazuyuki; Sueki, Akane; Taira, Chiaki; Uehara, Masayuki; Saito, Yasunori; Honda, Takayuki;
CLINICA CHIMICA ACTA, 448, 150-154, 2015 - Rapid single nucleotide polymorphism based method for hematopoietic chimerism analysis and monitoring using high-speed droplet allele-specific PCR and allele-specific quantitative PCR
Taira, Chiaki; Matsuda, Kazuyuki; Yamaguchi, Akemi; Uehara, Masayuki; Sugano, Mitsutoshi; Okumura, Nobuo; Honda, Takayuki;
CLINICA CHIMICA ACTA, 445, 101-106, 2015 - STAT3 gene mutations and their association with pure red cell aplasia in large granular lymphocyte leukemia
Ishida, Fumihiro; Matsuda, Kazuyuki; Sekiguchi, Nodoka; Makishima, Hideki; Taira, Chiaki; Momose, Kayoko; Nishina, Sayaka; Senoo, Noriko; Sakai, Hitoshi; Ito, Toshiro; Kwong, Yok-Lam;
CANCER SCIENCE, 105(3), 342-346, Mar. 2014 - Epithelial-mesenchymal transition of A549 cells is enhanced by co-cultured with THP-1 macrophages under hypoxic conditions
Sueki, Akane; Matsuda, Kazuyuki; Iwashita, Chinami; Taira, Chiaki; Ishimine, Nau; Shigeto, Shohei; Kawasaki, Kenji; Sugano, Mitsutoshi; Yamamoto, Hiroshi; Honda, Takayuki;
Biochemical and biophysical research communications, 453(4), 804-809, 2014 - Novel high-speed droplet-allele specific-polymerase chain reaction: Application in the rapid genotyping of single nucleotide polymorphisms
Taira, Chiaki; Matsuda, Kazuyuki; Yamaguchi, Akemi; Sueki, Akane; Koeda, Hiroshi; Takagi, Fumio; Kobayashi, Yukihiro; Sugano, Mitsutoshi; Honda, Takayuki;
CLINICA CHIMICA ACTA, 424, 39-46, 2013 - Rapid detection of PML-RARA fusion gene by novel high-speed droplet-reverse transcriptase-polymerase chain reaction: Possibility for molecular diagnosis without lagging behind the morphological analyses
Sueki, Akane; Matsuda, Kazuyuki; Taira, Chiaki; Yamaguchi, Akemi; Koeda, Hiroshi; Takagi, Fumio; Kobayashi, Yukihiro; Sugano, Mitsutoshi; Honda, Takayuki;
CLINICA CHIMICA ACTA, 415, 276-278, 2013 - Spliceosome-related gene mutations in myelodysplastic syndrome can be used as stable markers for monitoring minimal residual disease during follow-up
Matsuda, Kazuyuki; Ishida, Fumihiro; Ito, Toshiro; Nakazawa, Hideyuki; Miura, Shuhei; Taira, Chiaki; Sueki, Akane; Kobayashi, Yukihiro; Honda, Takayuki;
LEUKEMIA RESEARCH, 36(11), 1393-1397, Nov. 2012 - 子宮内胎児死亡の原因検索に頬粘膜細胞による間期核FISH法が有用であった1症例
竹澤 由夏; 古庄 知己; 松田 和之; 平 千明; 伊藤 友里花; 日高 惠以子; 菅野 光俊; 鳴海 洋子; 水内 麻子; 小原 久典; 涌井 敬子; 奥村 伸生; 福嶋 義光; 本田 孝行;
臨床病理, 60(1), 32-36, 25 Jan. 2012
- A novel high-speed droplet-polymerase chain reaction can detect human influenza virus in less than 30 min
Matsuda, Kazuyuki; Yamaguchi, Akemi; Taira, Chiaki; Sueki, Akane; Koeda, Hiroshi; Takagi, Fumio; Sugano, Mitsutoshi; Honda, Takayuki;
CLINICA CHIMICA ACTA, 413(21-22), 1742-1745, 2012 - Application of allele-specific quantitative PCR using genomic DNA to monitor minimal residual disease based on mutant gene levels following allogeneic hematopoietic stem cell transplantation in patients with hematological malignancies: Comparison of mutant levels with autologous DNA percentage by short tandem repeat-PCR
Taira, Chiaki; Matsuda, Kazuyuki; Saito, Shoji; Sakashita, Kazuo; Sugano, Mitsutoshi; Okumura, Nobuo; Honda, Takayuki;
CLINICA CHIMICA ACTA, 413(3-4), 516-519, 2012 - Genetic analysis of TP53 in childhood myelodysplastic syndrome and juvenile myelomonocytic leukemia
Saito, Shoji; Matsuda, Kazuyuki; Taira, Chiaki; Sano, Kenji; Tanaka-Yanagisawa, Miyuki; Yanagisawa, Ryu; Nakazawa, Yozo; Sakashita, Kazuo; Shiohara, Masaaki; Koike, Kenichi;
LEUKEMIA RESEARCH, 35(12), 1578-1584, Dec. 2011 - キメリズム解析における multiplex short tandem repeat(STR)-PCR 法の検討と検査材料の評価
平 千明; 松田 和之; 竹澤 由夏; 伊藤 俊朗; 石田 文宏; 日高 惠以子; 熊谷 俊子; 本田 孝行;
臨床病理, 59(1), 24-30, 25 Jan. 2011 - Quantitative monitoring of single nucleotide mutations by allele-specific quantitative PCR can be used for the assessment of minimal residual disease in patients with hematological malignancies throughout their clinical course
Taira, Chiaki; Matsuda, Kazuyuki; Kamijyo, Yuka; Sakashita, Kazuo; Ishida, Fumihiro; Kumagai, Toshiko; Yamauchi, Kazuyoshi; Okumura, Nobuo; Honda, Takayuki;
CLINICA CHIMICA ACTA, 412(1-2), 53-58, 2011 - Quantitative assessment of PTPN11 or RAS mutations at the neonatal period and during the clinical course in patients with juvenile myelomonocytic leukaemia
Matsuda, Kazuyuki; Sakashita, Kazuo; Taira, Chiaki; Tanaka-Yanagisawa, Miyuki; Yanagisawa, Ryu; Shiohara, Masaaki; Kanegane, Hirokazu; Hasegawa, Daiichiro; Kawasaki, Keiichiro; Endo, Mikiya; Yajima, Shuhei; Sasaki, Shinya; Kato, Keisuke; Koike, Kazutoshi; Kikuchi, Akira; Ogawa, Atsushi; Watanabe, Akihiro; Sotomatsu, Manabu; Nonoyama, Shigeaki; Koike, Kenichi;
BRITISH JOURNAL OF HAEMATOLOGY, 148(4), 593-599, Feb. 2010 - Long-term survival after nonintensive chemotherapy in some juvenile myelomonocytic leukemia patients with CBL mutations, and the possible presence of healthy persons with the mutations
Matsuda, Kazuyuki; Taira, Chiaki; Sakashita, Kazuo; Saito, Shoji; Tanaka-Yanagisawa, Miyuki; Yanagisawa, Ryu; Nakazawa, Yozo; Shiohara, Masaaki; Fukushima, Keitaro; Oda, Megumi; Honda, Takayuki; Nakahata, Tatsutoshi; Koike, Kenichi;
BLOOD, 115(26), 5429-5431, 2010 - Simple polymerase chain reaction for the detection of mutations and deletions in the epidermal growth factor receptor gene: Applications of this method for the diagnosis of non-small-cell lung cancer
Uhara, Miho; Matsuda, Kazuyuki; Taira, Chiaki; Higuchi, Yumiko; Okumura, Nubuo; Yamauchi, Kazuyoshi;
CLINICA CHIMICA ACTA, 401(1-2), 68-72, Mar. 2009
Books and other publications
- 臨床検査法提要 第35版
伊澤 淳, 加藤太門, 平 千明, 木下 修, 笠井宏樹, 元木博彦, 今村 浩, 三枝達也, 海老澤聡一郎, 桑原宏一朗, 山崎佐枝子, 井口純子, 他約110名, 第16章循環機能検査（Ⅲ心電図・心音図）1.「心電図検査概論」, 11.「心音と心周期」
金原出版, May 2020ナーシング・グラフィカEX 疾患と看護② 循環器
伊澤 淳, 仲村直子, 平 千明, 南澤匡俊, 三浦 崇, 千田啓介, 他45名, 3章3節「血圧測定・動脈硬化の検査」, 4節「心電図・心肺運動負荷試験」
株式会社メディカ出版, pp.56-66 Jan. 2020Lectures, oral presentations, etc.
- 心拍変動解析による月経時の自律神経機能評価
第69回日本臨床検査医学会学術集会, 19 Nov. 2022Roles of LA strain and NT-proBNP/hsTnT ratio in the diagnosis of atrial fibrillation
The 17th Congress of Asian Society for Clinical Pathology and Laboratory Medicine, 09 Oct. 2022Research Themes
- 一般財団法人長野県科学振興会、心拍変動測定アプリによる自律神経活動測定法の検証と月経セルフケアへの応用
2023 - 日本臨床検査医学会公募学術推進プロジェクト、MicroRNA測定法の標準化と心房細動での応用
2023 - 公益財団法人信州医学振興会、粥状動脈硬化巣モデルによるオステオポンチンの動態解明
2021 - 2021 - 公益財団法人 福田記念医療技術振興財団、新規心房細動評価指標の確立： microRNAおよび左房ストレインを組み合わせた多角的指標の有用性評価
2021 - 2021 - 分子異常フィブリノゲンの細胞外マトリックス機能に与える影響の評価と重要部位の同定
科学研究費補助金, 基盤研究（C）
2020 - 2022 - ホクト生物科学振興財団助成、循環器疾患患者におけるVEGF遺伝子プロモーター領域（-2549）多型頻度および培養細胞を用いた機能解析
2020 - 2020 - 頭痛関連SNPと心拍変動解析法を組合わせた一次性頭痛鑑別法の新規構築
科学研究費補助金, 若手研究
2018 - 2021 - ノバルティス研究助成、SNPおよびmicroRNAを指標とした頭痛鑑別法の構築
2018 - フィブリノゲン機能異常症の解析からフィブリン重合機序の詳細を解明する研究
科学研究費補助金, 基盤研究（C）
2017 - 2019 - グラクソ・スミスクラインジャパン研究助成、低酸素下での血管内皮細胞EndMT誘導とmiRNA解析による肺線維化促進の解明
2017 - 2019 - 公益信託 臨床検査医学研究振興基金、老化肺胞２型細胞とマクロファージ共培養における肺線維化との関連性の検討
2014 - 2014 - 公益財団法人 信州医学振興会、液滴型高速PCRを用いた、小児急性リンパ芽急性白血病におけるメトトレキサート毒性関連SNPの迅速な検出法の検討
2013 - 2013 - 公益財団法人 黒住医学研究振興財団、特発性肺線維症における肺線維化とNeu1の関連性と新たなバイオマーカーとしての有用性の検討
2012 - 2012 - びまん性肺疾患患者における気管支肺胞洗浄液中シアリダーゼの解析、症例研究
科学研究費補助金, 症例研究
2011 - 2011 - 操作効率の良いキメリズム解析法の検討及び検査材料の評価、症例研究
科学研究費補助金, 症例研究
2010 - 2010 - 公益財団法人信州医学振興会、測定原理の異なる各種感染症検出法の比較検討
2010 - 2010
