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ICHIKAWA Iekuni

Academic OrganizationTEL
Education and Research OrganizationSchool of MedicineFAX
PositionProfessorMail Address
Address3-1-1, Asahi, Matsumoto City 390-8621Web site

Modified:07/19/2021

Profile

Current Subject
glomerulosclerosis
Keywords:podocyte , CAKUT , Renal Diseases
Academic Background
College
1972
Awards
2007
2000

Research

Books, Articles, etc.
Articles
Doping Doctors: The Influence of the Marketing Departments of Pharmaceutical Companies on Physician and Researcher Behavior in Japan.
Account Res,23(4):245-53 2016
Author:Ichikawa I, Clayton EW.


Genome-wide association study of IgA nephropathy using 23 465 microsatellite markers in a Japanese population.
J Hum Genet,60(10):573-80 2015(Oct.)
Author:Saka S, Hirawa N, Oka A, Yatsu K, Hirukawa T, Yamamoto R, Matsusaka T, Imai E, Narita I, Endoh M, Ichikawa I, Umemura S, Inoko H.


Unilateral ureteral obstruction attenuates intrarenal angiotensin II generation induced by podocyte injury.
Am J Physiol Renal Physiol,308(8):F932-7 2015(Apr.)
Author:Okabe M, Miyazaki Y, Niimura F, Pastan I, Nishiyama A, Yokoo T, Ichikawa I, Matsusaka T.


Authorship guidelines and actual practice: are they harmonized in different research systems?
J Microbiol Biol Educ,15(2):155-158 2014(Dec.)
Author:Vasconcelos S, Vasgird D, Ichikawa I, Plemmons D


Podocyte injury enhances filtration of liver-derived angiotensinogen and renal angiotensin II generation
Kidney Int,85(5):1068-1077 2014(May)
Author:Matsusaka T, Niimura F, Pastan I, Shintani A, Nishiyama A, Ichikawa I


Mice are unable to endogenously regenerate podocytes during the repair of immunotoxin-induced glomerular injury
Nephrol Dial Transplant,29(5):1005-1012 2014(May)
Author:Miyazaki Y, Shimizu A, Ichikawa I, Hosoya T, Pastan I, Matsusaka T


Kidney Diseases Enhance Expression of Tetraspanin-8: A Possible Protective Effect against Tubular Injury
Nephron Extra,4(1):70-81 2014(Apr.)
Author:Hirukawa T, Wu Q, Sawada K, Matsusaka T, Saka S, Oka A, Hirawa N, Umemura S, Kakuta T, Endoh M, Inoko H, Ichikawa I, Fukagawa M


Foxc1 gene null mutation causes ectopic budding and kidney hypoplasia but not dysplasia
Cells Tissues Organs,198(1):22-27 2013
Author:Komaki F, Miyazaki Y, Niimura F, Matsusaka T, Ichikawa I, Motojima M


Liver Angiotensinogen Is the Primary Source of Renal Angiotensin II
Journal of the American Society of Nephrology,23(7):1181-9 2012(Apr. 19)
Author:Matsusaka T, Niimura F, Shimizu A, Pastan I, Saito A, Kobori H, Nishiyama A, Ichikawa I.
Keywords:angiotensin II/proteinuria/angiotensinogen


Podocyte injury damages other podocytes. Study of genetically engineered chimeric glomeruli.
J Am Soc Nephrol.,22:1275-1285 2011
Author:Matsusaka T, Sandgren E, Shintani A, Kon V, Pastan I, Fogo AB, Ichikawa I.


Glomerular sclerosis is prevented during urinary tract obstruction due to podocyte protection.
Am J Physiol Renal Physiol,300:F792-800 2011
Author:Matsusaka T, Kobayashi K, Kon V, Pastan I, Fogo AB, Ichikawa I.


Induction of podocyte-derived VEGF ameliorates podocyte injury and subsequent abnormal glomerular development caused by puromycin aminonucleoside.
Ped Res,70:83-89 2011
Author:Ma J, Matsusaka T, Yang H-C, Zhong J, Takagi N, Fogo AB, Kon V, Ichikawa I.


Plasma Macromolecules Activate Toll-like receptor 2 and 4 that May Promote Podocyte Injury.
Nephron Exp Nephrol,114:e39-e 2010
Author:Motojima M, Matsusaka T, Ichikawa I.


Angiotensin receptor blocker protection against podocyte-induced sclerosis is podocyte angiotensin II type 1 receptor-Independent.
Hypertension,55:967-973 2010
Author:Matsusaka T, Asano T, Niimura F, Kinomura M, Shimizu A, Shintani A, Pastan I, Fogo AB, Ichikawa I.


Genetic Podocyte Lineage Reveals Progressive Podocytopenia withParietal Cell Hyperplasia in a Murine Model of Cellular/Collapsing Focal Segmental Glomerulosclerosis
Am. J. Pathol.,174(5):1675 - 1682 2009(May 01)
Author:Suzuki T, Matsusaka T, Nakayama M, Asano T, Watanabe T, Ichikawa I, and Nagata M.


The impact of recent revisions in the Japanese ethical guidelines for clinical research.
Asian Bioethics Review 1,1:329-341 2009
Author:Motojima M, Ichikawa I.


Bmp4 podocytes is essential for normal glomerular capillary formation.
J Am Soc Nephrol,19:685-694 2008
Author:Ueda H, Miyazaki Y, Matsusaka T, Utsunomiya Y, Kawamura T, Hosoya T, Ichikawa I.


Megalin participates in the early injury of proximal tubule cells via reabsorption of filtered macromolecules in glomerular disease with non-selective proteinuria.
Kidney Int,74:1262-1269 2008
Author:Motoyoshi Y, Matsusaka T, Saito A, Pastan I, Willnow TE, Mizutani S, Ichikawa I.


Effects of Podocyte Injury on Glomerular Development.
Ped Res,62(4):417-421 2007
Author:Ma J, Rossini M, Yang HC, Zuo Y, Fogo AB, Ichikawa I.


Angiotensin inhibition decreases progression of advanced atherosclerosis and stabilizes established atherosclerotic plaques.
J Am Soc Nephrol.,18:2311-2319 2007
Author:Suganuma E, Babaev VR, Motojima M, Zuo Y, Ayabe N, Fogo AB, Ichikawa I, Linton MF, Fazio S, Kon V.


Inhibition of endogenous BMP in the glomerulus leads to mesangial matrix expansion.
Biochem Biophys Res Commun.,340(2):681-688 2006(Feb. 10)
Author:Miyazaki Y, Ueda H, Yokoo T, Utsunomiya Y, Kawamura T, Matsusaka T, Ichikawa I, Hosoya T


Antiatherogenic effects of angiotensin receptor antagonism in mild renal dysfunction.
J Am Soc Nephrol.,17(2):433-441 2006(Feb.)
Author:Suganuma E, Zuo Y, Ayabe N, Ma J, Babaev VR, Linton MF, Fazio S, Ichikawa I, Fogo AB, Kon V


Transiently heightened angiotensin II has distinct effects on atherosclerosis and aneurysm formation in hyperlipidemic mice.
Atherosclerosis.,184(2):312-321 2006(Feb.)
Author:Ayabe N, Babaev VR, Tang Y, Tanizawa T, Fogo AB, Linton MF, Ichikawa I, Fazio S, Kon V


HIV-1 Genes, vpr and nef, synergistically damage podocytes leading to glomerulosclerosis.
J Am Soc Nephrol.,17:2832-2843 2006
Author:Zuo Y, Matsusaka T, Zhong J, Ma J, Ma L, Hanna Z, Jolicoeur P, Fogo AB, Ichikawa I.


Expression of HIV-1 genes in podocytes alone can lead to the full spectrum of HIV-1-associated nephropathy.
Kidney Int.,68(3):1048-106 2005(Sep.)
Author:Zhong J, Zuo Y, Ma J, Fogo AB, Jolicoeur P, Ichikawa I, Matsusaka T


Permanent genetic tagging of podocytes: fate of injured podocytes in a mouse model of glomerular sclerosis.
J Am Soc Nephrol.,16(8):2257-2262 2005(Aug.)
Author:Asano T, Niimura F, Pastan I, Fogo AB, Ichikawa I, Matsusaka T


Genetic engineering of glomerular sclerosis in the mouse via control of onset and severity of podocyte-specific injury.
J Am Soc Nephrol,16:1013-1023 2005
Author:Matsusaka T, Xin J, Niwa S, Kobayashi K, Akatsuka A, Hashizume H, Wang Q, Pastan I, Fogo AB, Ichikawa I.


Rapid downregulation of beta-actin-based CAG promoter and filamentous actin in injured podocytes.
J Med Dent Sci,52(2):129-134 2005
Author:Asano T, Matsusaka T, Mizutani S, Ichikawa I.

Education

Lectures
2012
2012