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MATOBA Hisanori|Shinshu University Researcher List

MATOBA Hisanori

School of Medicine Department of Infection and Host Defense 

Assistant Professor 

Educational Background

  • 2015 - 2019, Shinshu university school of medicine, doctoral course in department of molecular pathology
  • 2003 - 2009, Shinshu University, School of Medicine
Research activity information

Paper

  • Sirt3 regulates proliferation and progesterone production in Leydig cells via suppression of reactive oxygen species.
    Hisanori Matoba; Chifumi Fujii; Kazuaki Maruyama; Masatomo Kawakubo; Masanobu Momose; Kenji Sano; Hitomi Imamura; Hiroki Kurihara; Jun Nakayama
    Endocrinology, 13 Feb. 2024, Refereed
    Lead, Corresponding電子ジャーナル
  • Identification of Terminal βGlcNAc on Brachyspira Species in Human Intestinal Spirochetosis
    Hisanori Matoba; Mai Iwaya; Chifumi Fujii; Jun Nakayama
    Journal of Histochemistry & Cytochemistry, 08 Jan. 2024, Refereed
    Lead, Corresponding電子ジャーナル
  • A spatio-temporal image analysis for growth of indeterminate pulmonary nodules detected by CT scan
    Takaomi Hanaoka; Hisanori Matoba; Jun Nakayama; Shotaro Ono; Kayoko Ikegawa; Mitsuyo Okada
    Radiological Physics and Technology, 27 Oct. 2023, Refereed電子ジャーナル
  • Citrullinated fibrinogen-SAAs complex causes vascular metastagenesis
    Yibing Han; Takeshi Tomita; Masayoshi Kato; Norihiro Ashihara; Yumiko Higuchi; Hisanori Matoba; Weiyi Wang; Hikaru Hayashi; Yuji Itoh; Satoshi Takahashi; Hiroshi Kurita; Jun Nakayama; Nobuo Okumura; Sachie Hiratsuka
    NATURE COMMUNICATIONS, 14(1), 24 Aug. 2023, Refereed電子ジャーナル
  • Increased GS‐II lectin binding and SATB2 downregulation are biological features for sessile serrated lesions and microvesicular hyperplastic polyps
    Hisanori Matoba; Mai Iwaya; Yoshiko Sato; Noriyasu Kobayashi; Haruka Takemura; Yusuke Kouno; Ayumi Karasawa; Jun Nakayama
    PATHOLOGY INTERNATIONAL, 73(6), 246-254, 10 Apr. 2023, Refereed
    Lead, Corresponding電子ジャーナル
  • PDGFRB and NOTCH3 Mutations are Detectable in a Wider Range of Pericytic Tumors, Including Myopericytomas, Angioleiomyomas, Glomus Tumors, and Their Combined Tumors
    Ryuji Iwamura; Kazuki Komatsu; Midori Kusano; Chisachi Kubo; Yuna Inaba; Eisuke Shiba; Aya Nawata; Ryosuke Tajiri; Atsuji Matsuyama; Hisanori Matoba; Kaori Koga; Maiko Takeda; Hiroe Itami; Masanori Hisaoka
    MODERN PATHOLOGY, 36(3), 100070-100070, Mar. 2023, Refereed電子ジャーナル
  • α1,4‐Linked N‐acetylglucosamine suppresses gastric cancer development by inhibiting Mucin‐1‐mediated signaling
    Chifumi Fujii; Satoru Harumiya; Yoshiko Sato; Masatomo Kawakubo; Hisanori Matoba; Jun Nakayama
    CANCER SCIENCE, 113(11), 3852-3863, 31 Aug. 2022, Refereed電子ジャーナル
  • Mucin distribution in bronchiolar adenoma/ciliated muconodular papillary tumor reveals organoid differentiation simulating the normal lung
    Hisanori Matoba; Meguru Ikeyama; Noriyasu Kobayashi; Haruka Takemura; Takaomi Hanaoka; Yoshiko Sato; Jun Nakayama
    PATHOLOGY INTERNATIONAL, 72(5), 300-306, 09 Mar. 2022, Refereed
    Lead, Corresponding電子ジャーナル
  • Glycosylation of MUC6 by α1,4‐linked N‐acetylglucosamine enhances suppression of pancreatic cancer malignancy
    Atsuko Yuki; Chifumi Fujii; Kazuhiro Yamanoi; Hisanori Matoba; Satoru Harumiya; Masatomo Kawakubo; Jun Nakayama
    CANCER SCIENCE, 113(2), 576-586, 28 Nov. 2021, Refereed電子ジャーナル
  • Decreased Gastric Gland Mucin-specific O-glycans Are Involved in the Progression of Ovarian Primary Mucinous Tumours
    Ayumi Ohya; Hisanori Matoba; Yasunari Fujinaga; Jun Nakayama
    ACTA HISTOCHEMICA ET CYTOCHEMICA, 54(4), 115-122, 25 Aug. 2021, Refereed電子ジャーナル
  • Cholestenone functions as an antibiotic against Helicobacter pylori by inhibiting biosynthesis of the cell wall component CGL
    Junichi Kobayashi; Masatomo Kawakubo; Chifumi Fujii; Nobuhiko Arisaka; Masaki Miyashita; Yoshiko Sato; Hitomi Komura; Hisanori Matoba; Jun Nakayama
    Proceedings of the National Academy of Sciences, 118(16), 14 Apr. 2021, Refereed電子ジャーナル
  • HDAC6 inhibition enhances the anti-tumor effect of eribulin through tubulin acetylation in triple-negative breast cancer cells
    Takaaki Oba; Mayu Ono; Hisanori Matoba; Takeshi Uehara; Yoshie Hasegawa; Ken-ichi Ito
    Breast Cancer Research and Treatment, 186(1), 37-51, 16 Jan. 2021, Refereed電子ジャーナル
  • Useful preoperative examination findings to classify the grade of ovarian primary mucinous tumor
    Ayumi Ohya; Fumihito Ichinohe; Hisanori Matoba; Hisanori Kobara; Yasunari Fujinaga
    Abdominal Radiology, 46(6), 2393-2402, 02 Jan. 2021, Refereed電子ジャーナル
  • Cecal Tumorigenesis in Aryl Hydrocarbon Receptor–Deficient Mice Depends on Cecum-Specific Mitogen-Activated Protein Kinase Pathway Activation and Inflammation
    Hisanori Matoba; Masaya Takamoto; Chifumi Fujii; Masatomo Kawakubo; Eriko Kasuga; Tomio Matsumura; Tatsuya Natori; Ken Misawa; Shun'ichiro Taniguchi; Jun Nakayama
    The American Journal of Pathology, 190(2), 453-468, Feb. 2020, Refereed
    Lead電子ジャーナル
  • 内反性膀胱癌の1例
    平林直樹; 西澤理; 小林則康; 池山環; 的場久典; 中山淳
    泌尿器科紀要, 65, 463-467, Nov. 2019, Refereed
  • Clinical features and new diagnostic criteria for the syndrome of periodic fever, aphthous stomatitis, pharyngitis, and cervical adenitis
    Yusuke Takeuchi; Tomonari Shigemura; Norimoto Kobayashi; Haruo Nagumo; Masahiro Furumoto; Kyo Ogasawara; Hitomi Fujii; Masahiro Takizawa; Takashi Soga; Hisanori Matoba; Junya Masumoto; Keitaro Fukushima; Kiyoshi Migita; Toshiyuki Ojima; Yoh Umeda; Kazunaga Agematsu
    INTERNATIONAL JOURNAL OF RHEUMATIC DISEASES, 22(8), 1489-1497, 27 May 2019, Refereed電子ジャーナル
  • Juvenile onset autoinflammatory disease due to a novel mutation in TNFAIP3 (A20)
    Shuzo Sato; Yuya Fujita; Tomonari Shigemura; Hisanori Matoba; Kazunaga Agematsu; Yuya Sumichika; Makiko Yashiro; Atsushi Ono; Yukihiko Kawasaki; Hiroko Kobayashi; Hiroshi Watanabe; Tomohiro Koga; Atsushi Kawakami; Kiyoshi Migita
    Arthritis Research & Therapy, 20(1), 10 Dec. 2018, Refereed電子ジャーナル
  • Unexpected Occurrence of Fetal Hemophagocytic Syndrome in a Patient with Hereditary Diffuse Leukoencephalopathy with Spheroids
    Yasufumi Kondo; Michiaki Kinoshita; Takuhiro Yoshida; Hisanori Matoba; Takeshi Uehara; Meguru Ikeyama; Jun Nakayama; Kunihiro Yoshida; Shu-Ichi Ikeda
    Case Reports in Clinical Medicine, 05(03), 77-84, 2016, Refereed電子ジャーナル
  • A case of MUC5AC-positive intraductal neoplasm of the pancreas classified as an intraductal tubulopapillary neoplasm?
    Takashi Muraki; Takeshi Uehara; Kenji Sano; Hiroyoshi Oota; Akihiko Yoshizawa; Shiho Asaka; Ayako Tateishi; Toshiaki Otsuki; Kunihiko Shingu; Hisanori Matoba; Shota Kobayashi; Shojiro Ichimata; Takayuki Watanabe; Tetsuya Itou; Eiji Tanaka
    Pathology - Research and Practice, 211(12), 1034-1039, Dec. 2015, Refereed電子ジャーナル
  • Cutaneous plasmacytosis associated with autoimmune hemolytic anemia
    Yukiko Kiniwa; Hisanori Matoba; Hideaki Hamano; Yasushi Senoo; Ryuhei Okuyama
    The Journal of Dermatology, 43(3), 343-345, 21 Nov. 2015, Refereed電子ジャーナル
  • 食道胃接合部発生の原発性絨毛癌の1例
    的場久典; 立石文子; 小林実喜子; 岸本恭; 太田浩良; 本田孝行
    診断病理, 32, 218-222, Jun. 2015, Refereed
    Lead, Corresponding
  • Hypertrophic Pulmonary Osteoarthropathy in Anaplastic Lymphoma Kinase (ALK)-positive Lung Cancer
    Masamichi Komatsu; Masanori Yasuo; Nobumitsu Kobayashi; Kazunari Tateishi; Atsuhito Ushiki; Kazuhisa Urushihata; Hiroshi Yamamoto; Masayuki Hanaoka; Hisanori Matoba; Takayuki Honda; Kosuke Ichikawa
    INTERNAL MEDICINE, 54(16), 2045-2049, 2015, Refereed電子ジャーナル
  • A somatotropin-producing pituitary adenoma with an isolated adrenocorticotropin-producing pituitary adenoma in a female patient with acromegaly, subclinical Cushing’s disease and a left adrenal tumor
    Yuki Kobayashi; Masahiro Takei; Yohsuke Ohkubo; Yukinari Kakizawa; Hisanori Matoba; Mieko Kumagai; Teiji Takeda; Satoru Suzuki; Mitsuhisa Komatsu
    Endocrine journal, 61(6), 589-595, 2014, Refereed電子ジャーナル
  • 癌肉腫,扁平上皮癌,腺様成分を伴った食道神経内分泌癌の1例
    大上康広; 小出直彦; 鈴木彰; 竹内大輔; 奥村征大; 的場久典; 岩谷舞; 宮川眞一
    日本消化器外科学会雑誌, 46, 647-653, Apr. 2013, Refereed

Lectures, oral presentations, etc.

  • Increase of terminal βGlcNAc is a biological feature of human intestina l spirochetosis
    Mai Iwaya; Hisanori Matoba; Jun Nakayama
    The 112th annual meeting of the Japanese society of pathology, Apr. 2023
  • MUC6へのαGlcNAc結合は膵癌細胞の悪性形質の抑制を増強させる
    藤井千文; 山ノ井一裕; 的場久典; 中山淳
    第81回日本癌学会学術総会 (神奈川), Sep. 2022
  • Increase of terminal βGlcNAc and downregulation of SATB2 are biomarkers for sessile serrated lesion
    Hisanori Matoba; Mai Iwaya; Jun Nakayama
    The 111th annual meeting of the Japanese society of pathology, Apr. 2022
  • Sirt3-knockdown induces ROS-dependent cell death in MA-10 Leydig tumor cells
    Hisanori Matoba; Chifumi Fujii; Masatomo Kawakubo; Kazuaki Maruyama; Jun Nakayama
    The 110th annual meeting of the Japanese society of pathology, Apr. 2021
  • Cecal tumorigenesis in AhR-deficient mice depends on cecum-specific MAPK activation and inflammation
    Hisanori Matoba; Masaya Takamoto; Chifumi Fujii; Masatomo Kawakubo; Eriko Kasuga; Tomio Matsumura; Tatsuya Natori; Ken Misawa; Shun’ichiro Taniguchi; Jun Nakayama
    The 109th annual meeting of the Japanese society of pathology, 16 Apr. 2020
  • 乳腺化生癌の一例
    三澤健; 平嶋早百合; 河野佑介; 藤原正之; 中村智次; 的場久典; 江原孝史
    第58回日本臨床細胞学会秋期大会(岡山), Nov. 2019
  • 子宮頸部細胞診で胃型粘液性癌が疑われた通常型内頸部腺癌の一例
    服部守恭; 藤井真; 山ノ井一裕; 中山淳; 福島万奈; 的場久典
    第58回日本臨床細胞学会秋期大会(岡山), Nov. 2019
  • 子宮体部小細胞神経内分泌癌の一例
    河野佑介; 平嶋早百合; 三澤健; 藤原正之; 中村智次; 的場久典; 江原孝史
    第58回日本臨床細胞学会秋期大会(岡山), Nov. 2019
  • AhRノックアウトマウスの盲腸への腫瘍発生およびそれに対する腸内細菌叢の影響に関する研究
    的場久典; 藤井千文; 谷口俊一郎; 中山淳
    第77回日本癌学会学術総会 (大阪), Sep. 2018
  • AhRノックアウトマウスの盲腸への腫瘍発生および腸内細菌叢の影響に関する研究
    的場久典; 藤井千文; 川久保雅友; 春日恵理子; 高本雅哉; 谷口俊一郎; 中山淳
    第107回病理学会総会 (札幌), Jun. 2018
  • 腫瘍発生におけるSirtuin3 の役割に関する免疫組織化学的検討
    的場久典; 百瀬正信; 佐野健司
    第106回病理学会総会 (東京), Apr. 2016
  • 食道胃接合部発生の原発性絨毛癌の1例
    的場久典; 立石文子; 小林実喜子; 太田浩良
    第104回病理学会総会 (名古屋), May 2015
  • Carcinosarcoma arising from eccrine spiroadenoma の一例
    的場久典; 岩谷舞; 吉澤明彦; 浅香志穂; 菅野祐幸
    第102回日本病理学会総会 (札幌), Jun. 2013
  • 軟部低悪性度平滑筋肉腫の1例
    的場久典; 吉澤明彦; 佐野健司; 浅香志穂; 本田孝行
    第101回日本病理学会総会 (東京), Apr. 2012
  • αGlcNAcとMUC6による膵癌の悪性化制御機構
    藤井千文; 結城淳子; 山ノ井一裕; 的場久典; 春宮覚; 川久保雅友; 中山淳
    第31回日本がん転移学会学術集会 (京都)

Affiliated academic society

  • 2011
    The Japanese Society of Pathology
  • 2016
    Japan Cancer Assosiation
  • The Japanese society of clinical cytology
  • 2014
    The Japanese society of clinical cytology

Research Themes

  • 炎症性腸疾患の網羅的メチル化解析に基づく発癌マウスモデル構築と診断マーカーの探索
    科学研究費補助金, 若手研究
    2024 - 2026
  • 炎症性腸疾患からの発癌におけるAhRの役割と新規がんマーカーとしての有用性
    科学研究費補助金, 若手研究
    2021 - 2023
  • 腸内細菌叢の変化によるAhR ノックアウトマウスの回盲部での発癌促進機構
    科学研究費補助金, 研究活動スタート支援
    2019 - 2020