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ARAI Yusuke

Academic OrganizationAcademic Assembly School of Medicine and Health Sciences Institute of MedicineTEL
Education and Research OrganizationShinshu University Hospital NeuropsychiatryFAX
PositionAssistant ProfessorMail Address
Address3-1-1, Asahi, Matsumoto City 390-8621Web site

Profile

Research Field
Neuroscience - general
Cognitive neuroscience
Clinical pharmacy
Psychiatry
Keywords:Screen time , 過眠症 , 注意欠如多動症 , 精神医学 , 睡眠医学
Academic Societies
Academic Societies
信州精神神経学会
日本児童青年精神医学会
日本認知症予防学会
日本睡眠学会
日本精神神経学会
Academic Background
Graduate School
Shinshu University , (医学系 , Graduate School of Medicine, Science and Technology) , 2023

College
University of Miyazaki , (Faculty of Medicine) , 2014

Degree
Doctor of Philosophy , Shinshu University
Research Career
Research Career
2023- , Shinshu University Hospital Neuropsychiatry, Shinshu University
2019-2023 , Kurita Hospital
2018-2019 , Nihon University
2016-2019 , Kurita Hospital

Research

Books, Articles, etc.
Articles
Association between Children’s Difficulties, Parent-Child Sleep, Parental Control, and Children’s Screen Time: A Cross-Sectional Study in Japan
Pediatric Reports,15(4):668-678 2023(Nov. 08)
Author:Yusuke Arai; Daimei Sasayama; Kazuhiro Suzuki; Toshinori Nakamura; Yuta Kuraishi; Shinsuke Washizuka
Abstract:Children’s screen time may affect their growth and development. However, differences in the impact of various psychiatric and psychological factors on children’s screen time is a research gap. This study aimed to explore the differences in the influence of related factors affecting children’s screen time based on their sleep, difficulties, and parental control among Japanese elementary and junior high school students. A cross-sectional survey was conducted among parents in Japan. Data on screen time duration, parent–child background, strengths and difficulties, sleep variables, and parental control types were collected from 225 households. A regression analysis revealed that high Strengths and Difficulties Questionnaire (SDQ) scores (β = 0.166, p = 0.008), sleep duration (β = −0.281, p < 0.001), and parental control (β = −0.204, p = 0.001) were significantly related to children’s screen time. Additionally, it was found that parents’ late bedtimes affect children’s screen time by mediating children’s sleep duration. This study, together with previous research, provides comprehensive insights into design interventions to decrease the screen time of children in the Japanese context.


Sodium Valproate Use in Japanese Patients with Schizophrenia and Coronavirus Disease Is Associated with an Increased Risk of Pneumonia
Journal of Clinical Medicine,12(18):5953-5953 2023(Sep. 13)
Author:Yusuke Arai; Daimei Sasayama; Akira Kuraishi; Reiko Sahara; Shiho Murata; Akira Tanaka; Kotaro Amemiya; Nobuteru Usuda; Kazuaki Kuraishi; Shinsuke Washizuka
Abstract:Schizophrenia is a known risk factor for coronavirus disease (COVID-19) infection and severity, and certain psychotropic drugs have been linked to increased mortality in infected patients with schizophrenia. However, little evidence exists regarding this risk. We retrospectively examined the association between mood stabilizers and the risk of pneumonia in patients with schizophrenia. This study included 99 patients with schizophrenia or schizoaffective disorder who were infected with COVID-19 in 2022 and met the inclusion criteria. After conducting propensity score matching to align patient backgrounds and concomitant medications, we assessed the impact of mood stabilizers, specifically sodium valproate, on the risk of pneumonia development. Univariate analysis revealed that patients with schizophrenia and COVID-19 who developed pneumonia were more likely to be older (64.5 [14.2] vs. 57.4 [11.5] years, p = 0.008) and using sodium valproate (44.4% vs. 16.7%, p = 0.004). Even after propensity score matching, patients who developed pneumonia were still more likely to be receiving sodium valproate than not (58.8% vs. 20.0%, p = 0.003). Sodium valproate use may be a risk factor for the development of pneumonia in patients with chronic schizophrenia who are infected with COVID-19 during long-term hospitalization.


Parental Control and Children's Short Sleep Duration and Difficulties as Predictors of Screen Time: The Japanese Context
2023(Sep. 07)
Author:Yusuke Arai; Daimei Sasayama; Kazuhiro Suzuki; Toshinori Nakamura; Yuta Kuraishi; Shinsuke Washizuka
Abstract:Children&#039;s screen time may affect their growth and development. However, different aspects of children and their parents that affect children&#039;s screen time has not been investigated in the Japanese context. This study aimed to explore the relationship between relevant factors affecting children&#039;s screen time based on their sleep, difficulties, and parental control, among Japanese elementary and junior high school students. A cross-sectional survey was conducted among parents in Japan. Data on screen time duration, parent-child background, strengths and difficulties, sleep variables, and parental control types were collected from 225 households. Path analysis revealed that high Strengths and Difficulties Questionnaire (SDQ) scores (β = 0.167, p = 0.007), sleep duration (β = -0.282, p &amp;lt; 0.001), and parental control (β = -0.205, p &amp;lt; 0.001) were significantly related to children&#039;s screen time. Additionally, late parental bedtime negatively correlated with children&#039;s sleep duration (β = -0.326, p &amp;lt; 0.001). The findings suggest that children&#039;s difficulties, sleep duration, and parental control are associated with children&#039;s screen time. This study, together with previous research, provides comprehensive insights to design interventions to decrease screen time in children in the Japanese context.


Analysis of the effect of brexpiprazole on sleep architecture in patients with schizophrenia: A preliminary study.
Neuropsychopharmacology reports,43(1):112-119 2023(Mar.)
Author:Yusuke Arai; Daimei Sasayama; Kazuaki Kuraishi; Shiho Murata; Nobuteru Usuda; Mika Tsuchida; Yuka Nakajima; Shinsuke Washizuka
Abstract:BACKGROUND: Brexpiprazole is an atypical antipsychotic drug widely used in Japan for the treatment of schizophrenia. Previous studies have investigated the therapeutic effects of some antipsychotics on sleep variables; however, to our knowledge, the effects of brexpiprazole on sleep architecture have not been examined in patients with schizophrenia. Therefore, we aimed to exploratorily investigate the effect of brexpiprazole on sleep variables measured by polysomnography in patients with schizophrenia. METHODS: This study included 10 patients with schizophrenia who were originally treated with haloperidol alone. Sleep variables of the participants were measured using polysomnography. After excluding those who did not meet the study criteria, seven patients (five men and two women; mean age [SD], 59.0 [10.0] years) were eligible for further analysis. Polysomnography was repeated at 4 weeks after the participants were prescribed brexpiprazole in addition to haloperidol. We compared the sleep architecture of the participants, measured using polysomnography, before and after taking brexpiprazole. RESULTS: Add-on brexpiprazole significantly prolonged rapid eye movement latency, increased the duration and percentage of stage N2 and stage N3 sleep (min, %), and decreased the duration and percentage of stage rapid eye movement sleep (min, %) at a significance level of nominal p < 0.05. CONCLUSION: Although not significant after correcting for multiple comparisons, the present results showed that add-on brexpiprazole could alter the sleep architecture of patients with schizophrenia. Future studies are warranted to replicate these findings and to further investigate the beneficial influence of brexpiprazole on sleep.


A Case of Adult Tourette Syndrome: Iron Administration Reduces Tic Severity.
Psychiatria Danubina,34(4):719-721 2022
Author:Yusuke Arai; Daimei Sasayama; Yoshitaka Takeuchi; Shihoko Inada; Nobuteru Usuda; Akira Tanaka; Shiho Murata; Kazuaki Kuraishi; Shinsuke Washizuka


症例 アレルギー性気管支肺アスペルギルス症のスクリーニング
長野医療生活協同組合長野中央病院医報,8:14-16 2015
Author:荒井 勇輔; 近藤 知雄; 原 悠太


MISC
The 10th Congress of Asian Sleep Research Society and Asian Forum of Chronobiology, 2023
Sleep and Biological Rhythms,21(4):477-502 2023(Jul. 25)
Author:Yusuke Arai; Takashi Kanbayashi; Daimei Sasayama; Kazuaki Kuraishi; Shiho Murata; Nobuteru Usuda; Akira Tanaka; Shinsuke Washizuka


治療経過中に食事の拒否が続いた統合失調症患者の1例
精神神経学雑誌,125(6):541-541 2023(Jun.)
Author:齊藤 健太郎; 荒井 勇輔; 村田 志保; 倉石 和明


神社のほこらの倒壊と賽銭の窃盗を繰り返し、受診につながった知的障害の1例
精神神経学雑誌,124(9):666-666 2022(Sep.)
Author:酒井祐介 中村寛文 荒井勇輔 村田志保 倉石和明


睡眠時無呼吸症候群を併存したうつ病の1例
精神神経学雑誌,124(9):664-664 2022(Sep.)
Author:荒井勇輔; 村田志保; 倉石和明


鉄剤投与で症状の緩和を認めた成人期Tourette症の1例
精神神経学雑誌,121(7):577-577 2019(Jul.)
Author:荒井勇輔; 田中章; 竹内義孝; 稲田志穂子; 倉石和明


入院中の高齢者に対する睡眠薬投与の転倒リスク
第17回長野県民医連学術運動交流集会 2016(Mar.)
Author:荒井勇輔