MIYAHARA Hiroki
Interdisciplinary Cluster for Cutting Edge Research Institute for Biomedical Sciences
Assistant Professor
Researcher Information
Research activity information
Paper
- Macrophages in the reticuloendothelial system inhibit early induction stages of mouse apolipoprotein A-II amyloidosis
Miyahara H, Dai J, Li Y, Cui X, Takeuchi H, Hachiya N, Kametani F, Yazaki M, Mori M, Higuchi K
Amyloid, 30(2), 225-238, 2022
Lead, Corresponding - Exercise suppresses mouse systemic AApoAII amyloidosis through enhancement of the p38 MAPK signaling pathway
Cui X, Sawashita J, Dai J, Liu C, Igarashi Y, Mori M, Miyahara H, Higuchi K
Dis Model Mech, 15(3), dmm049327, 2022
Corresponding - Cyba and Nox2 mutant rats show different incidences of eosinophilia in the genetic background- and sex-dependent manner
Mori M, Dai J, Miyahara H, Li Y, Kang X, Yoshimi K, Mashimo T, Higuchi K, Mathumoto K
Exp Anim, 72(2), 233-241, 2022 - Polygenic control of the wavy coat of the NCT mouse: involvement of an intracisternal A particle insertional mutation of the protease, serine 53 (Prss53) gene, and a modifier gene
Mori M, Liu C, Yoshizawa T, Miyahara H, Dai J, Igarashi Y, Cui X, Li Y, Kang X, Higuchi K
Mamm Genome, 33(3), 451-464, 2022 - Glavonoid-rich oil supplementation reduces stearoyl-coenzyme A desaturase 1 expression and improves systemic metabolism in diabetic, obese KK-A mice
Yuichi Igarashi, Shiho Iida, Jian Dai, Jia Huo, Xiaoran Cui, Jinko Sawashita, Masayuki Mori, Hiroki Miyahara, Keiichi Higuchi
Biomedicine & Pharmacotherapy, 2021 - Curcumin promotes AApoAII amyloidosis and peroxisome proliferation in mice by activating the PPARα signaling pathway
Jian Dai, Ying Li, Fuyuki Kametani, Xiaoran Cui, Yuichi Igarashi, Jia Huo, Hiroki Miyahara, Masayuki Mori，Keiichi Higuchi
Elife, 2020 - Suppression of Mouse AApoAII Amyloidosis Progression by Daily Supplementation with Oxidative Stress Inhibitors
Dai J, Ding X, Miyahara H, Xu Z, Cui X, Igarashi Y, Sawashita J, Mori M, Higuchi K
Oxid Med Cell Longev, Volume 2019, 1263274, 2019 - Comprehensive proteomic profiles of mouse AApoAII amyloid fibrils provide insights into the involvement of lipoproteins in the pathology of amyloidosis
Miyahara H, Sawashita J, Ishikawa E, Yang M, Ding X, Liu Y, Hachiya N, Kametani F, Yazaki M, Mori M, Higuchi K
J Proteomics, (172), 111-121, 2018 - Apolipoprotein A-II induces acute-phase response associated AA amyloidosis in mice through conformational changes of plasma lipoprotein structure
Yang M, Liu Y, Dai J, Li L, Ding X, Xu Z, Mori M, Miyahara H, Sawashita J, Higuchi K
Sci Rep, (8), 5620, 2018 - Amyloidosis-inducing activity of blood cells in mouse AApoAII amyloidosis
Ding X, Liu Y, Yang M, Li L, Miyahara H, Dai J, Xu Z, Matsumoto, Mori M, Higuchi k, Sawashita J
Exp Anim, 67((2)), 105-115, 2018 - Coenzyme Q10 Prevents Senescence and Dysfunction Caused by Oxidative Stress in Vascular Endothelial Cells
Huo J, Xu Z, Hosoe K, Kubo H, Miyahara H, Dai J, Mori M, Sawashita J, Higuchi K
Oxid Med Cell Longev, 3181759, 2018 - Caloric restriction reduces the systemic progression of mouse AApoAII amyloidosis
Li L, Sawashita J, Ding X, Yang M, Xu Z, Miyahara H, Mori M, Higuchi K
PLOS ONE, 12((2)), e0172402, 2017 - Apolipoprotein A-II accelerates reactive AA amyloidosis
Yang M, Liu Y, Li L, Miyahara H, Ding X, Dai J, Sawashita J, Mori M, Higuchi K
Amyloid, 24((sup1)), 147-148, 2017 - Distribution of transmissible amyloid proteins in the liver with apolipoprotein A-II amyloidosis
Liu Y, Sawashita J, Wang Y, Li L, Miyahara H, Ding X, Yang M, Higuchi K
shinshu med J, 64((4)), 183-194, 2016 - Extracellular deposition of mouse senile AApoAII amyloid fibrils induced different unfolded protein responses in the liver, kidney, and heart
Luo H, Sawashita J, Tian G, Liu Y, Li L, Ding X, Xu Z, Yang M, Miyahara H, Mori M, Qian J, Wang Y, Higuchi K
Lab Invest, 95((3)), 320-33, 2015 - Factors to preserve CpG-rich sequences in methylated CpG islands
Miyahara H, Hirose O, Satou K, Yamada Y
BMC GENOMICS, (16), 144, 2015
Lectures, oral presentations, etc.
- A cellular model of amyloid degradation using macrophages cultured with mouse AApoAII amyloid fibrils
Hiroki Miyahara, Xiaoran Cui, Yuichi Igarashi, Ying Li, Jian Dai, Masayuki Mori, Keiichi Higuchi
The XVII International Symposium of Amyloidosis, 2020CURCUMIN PROMOTES PROGRESSION OF AApoAII AMYLOIDOSIS IN MICE BY ACTIVATING THE PPARα SIGNALING PATHWAY
Dai Jian, Cui Xiaoran, Igarashi Yuichi, Li Ying, Miyahara Hiroki, Mori Masayuki, Higuchi Keiichi
The XVII International Symposium of Amyloidosis, 2020Proteomic Profiles of Mouse AApoAII Amyloid Fibrils Provide Insights into the Involvement of Lipoproteins in the Pathology of Amyloidosis
Miyahara H, Mori M, Higuchi K
第18回日本蛋白科学会年会, 2018