SHIMIZU, Akira | Shinshu University Researcher Directory

Academic Organization	Academic Assembly　School of Medicine and Health Sciences　Institute of Medicine	TEL
Education and Research Organization	School of Medicine　Department of Surgery　Division of Gastroenterological, Hepato-Biliary-Pancreatic, Transplantation and Pediatric Surgery	FAX
Position	Associate Professor	Mail Address
Address	3-1-1 Asahi, Matsumoto, Nagano 390-8621	Web site

Profile

Academic Background: Degree
医学博士 , 信州大学

Research Career: Research Career
2015- , Lecturer
2007- , Assistant professor

Research

Books, Articles, etc.: Articles
A Case of Right Adrenal Carcinoma with Inferior Vena Cava Tumor Thrombus
The Shinshu Medical Journal,70(2):107-117 2022(Apr.)
Author:AOKI Ryosuke, Shimizu Akira, KUBOTA Koji, NOTAKE Tsuyoshi, HOSODA Kiyotaka, YASUKAWA Koya, HAYASHI Hikaru, SOEJIMA Yuji

Correlation of LGR5 expression and clinicopathological features in intrahepatic cholangiocarcinoma
PATHOLOGY RESEARCH AND PRACTICE,232:153832 2022(Apr.)
Author:Yoshizawa, Takahiro; Uehara, Takeshi; Iwaya, Mai; Asaka, Shiho; Kobayashi, Shota; Nakajima, Tomoyuki; Kinugawa, Yasuhiro; Nagaya, Tadanobu; Kamakura, Masato; Shimizu, Akira; Kubota, Koji; Notake, Tsuyoshi; Masuo, Hitoshi; Hosoda, Kiyotaka; Sakai, Hiroki; Hayashi, Hikaru; Umemura, Kentaro; Kamachi, Atsushi; Goto, Takamune; Tomida, Hidenori; Yamazaki, Shiori; Ota, Hiroyoshi; Soejima, Yuji;
Keywords:Leucine-rich repeat-containing G-protein-coupled receptor 5; Intrahepatic cholangiocarcinoma; RNA in situ hybridization;

ASO Author Reflections: Lymphocyte-to-monocyte ratio as prognostic biomarker in pancreatic ductal adenocarcinoma
ANNALS OF SURGICAL ONCOLOGY,29(2):1449-1450 2022(Feb.)
Author:Kubota, Koji; Shimizu, Akira; Soejima, Yuji;

Preoperative Peripheral Blood Lymphocyte-to-Monocyte Ratio Predicts Long-Term Outcome for Patients with Pancreatic Ductal Adenocarcinoma
ANNALS OF SURGICAL ONCOLOGY,29(2):1437-1448 2022(Feb.)
Author:Kubota, Koji; Shimizu, Akira; Notake, Tsuyoshi; Masuo, Hitoshi; Hosoda, Kiyotaka; Yasukawa, Koya; Hayashi, Hikaru; Umemura, Kentaro; Kamachi, Atsushi; Goto, Takamune; Tomida, Hidenori; Yamazaki, Shiori; Soejima, Yuji;

ASO Visual Abstract: Preoperative Peripheral Blood Lymphocyte-to-Monocyte Ratio Predicts Long-Term Outcome in Patients with Pancreatic Ductal Adenocarcinoma
ANNALS OF SURGICAL ONCOLOGY,29(2):1451-1452 2022(Feb.)
Author:Kubota, Koji; Shimizu, Akira; Notake, Tsuyoshi; Masuo, Hitoshi; Hosoda, Kiyotaka; Yasukawa, Koya; Hayashi, Hikaru; Umemura, Kentaro; Kamachi, Atsushi; Goto, Takamune; Tomida, Hidenori; Yamazaki, Shiori; Soejima, Yuji;

Asymptomatic Venous Thromboembolism After Hepatobiliary-Pancreatic Surgery: Early Detection Using D-dimer and Soluble Fibrin Monomer Complex Levels
ANNALS OF GASTROENTEROLOGICAL SURGERY,6(1):109-118 2022(Jan.)
Author:Hayashi, Hikaru; Shimizu, Akira; Kubota, Koji; Notake, Tsuyoshi; Sugenoya, Shinsuke; Masuo, Hitoshi; Hosoda, Kiyotaka; Yasukawa, Koya; Kobayashi, Ryoichiro; Soejima, Yuji;
Keywords:D-dimer; hepatobiliary-pancreatic surgery; prophylactic anticoagulation; soluble fibrin monomer complex; venous thromboembolism;

LGR5 expression and clinicopathological features of the invasive front in the fat infiltration area of pancreatic cancer
DIAGNOSTIC PATHOLOGY,17(1):21 2022
Author:Kamakura, Masato; Uehara, Takeshi; Iwaya, Mai; Asaka, Shiho; Kobayashi, Shota; Nakajima, Tomoyuki; Kinugawa, Yasuhiro; Nagaya, Tadanobu; Yoshizawa, Takahiro; Shimizu, Akira; Ota, Hiroyoshi; Umemura, Takeji;
Keywords:Leucine-rich repeat-containing G-protein-coupled receptor 5 (LGR5); RNA in situ hybridization; Pancreatic ductal adenocarcinoma; cancer stem cell; Fat invasion;

Gallbladder Burkitt's lymphoma mimicking gallbladder cancer: A case report
WORLD JOURNAL OF GASTROENTEROLOGY,28(6):675-682 2022
Author:Hosoda, Kiyotaka; Shimizu, Akira; Kubota, Koji; Notake, Tsuyoshi; Hayashi, Hikaru; Yasukawa, Koya; Umemura, Kentaro; Kamachi, Atsushi; Goto, Takamune; Tomida, Hidenori; Yamazaki, Shiori; Narusawa, Yuri; Asano, Naoko; Uehara, Takeshi; Soejima, Yuji;
Keywords:Gallbladder; Malignant lymphoma; Burkitt's lymphoma; Gallbladder cancer; Lymphadenopathy; Case report;

Survival Outcomes of Gemcitabine Plus S-1 Adjuvant Chemotherapy after Surgical Resection for Advanced Biliary Tract Cancer
ONCOLOGY,99(11):703-712 2021(Nov.)
Author:Hosoda, Kiyotaka; Fukushima, Kentaro; Shimizu, Akira; Motoyama, Hiroaki; Kubota, Koji; Notake, Tsuyoshi; Sugenoya, Shinsuke; Hayashi, Hikaru; Yasukawa, Koya; Kobayashi, Ryoichiro; Soejima, Yuji;
Keywords:Adjuvant chemotherapy; Biliary tract cancer; Gemcitabine; S-1; Surgical resection;

A Case of Liver Metastasis in Primary Renal Cell Carcinoma Diagnosed by Hepatectomy after 9 Years of Follow-up of Cystic Liver Lesion
The Shinshu Medical Journal,69(4):209-215 2021(Aug.)
Author:SHIMIZU Yuki, SUGIURA Ayumi, JOSHITA Satoru, KOBAYASHI Hiroyuki, WAKABAYASHI Shun-ichi, YAMASHITA Yuki, YAMAZAKI Tomoo, UEHARA Takeshi, SHIMIZU Akira, SOEJIMA Yuji,UMEMURA Takeji

The survival benefit of surgery for perihilar cholangiocarcinoma in octogenarians: Shinshu University experience
JOURNAL OF SURGICAL ONCOLOGY,124(1):67-78 2021(Jul.)
Author:Yasukawa, Koya; Shimizu, Akira; Kubota, Koji; Notake, Tsuyoshi; Sugenoya, Shinsuke; Hosoda, Kiyotaka; Ikehara, Tomohiko; Hayashi, Hikaru; Kobayashi, Ryoichiro; Soejima, Yuji;
Keywords:aging society; biomarker; octogenarian; older patients; perihilar cholangiocarcinoma;

Safety and Oncological Benefit of Hepatopancreatoduodenectomy for Advanced Extrahepatic Cholangiocarcinoma with Horizontal Tumor Spread: Shinshu University Experience
ANNALS OF SURGICAL ONCOLOGY,28(4):2012-2025 2021(Apr.)
Author:Shimizu, Akira; Motoyama, Hiroaki; Kubota, Koji; Notake, Tsuyoshi; Fukushima, Kentaro; Ikehara, Tomohiko; Hayashi, Hikaru; Yasukawa, Koya; Kobayashi, Akira; Soejima, Yuji;

Applicability of sentinel lymph node oriented treatment strategy for gallbladder cancer
PLOS ONE,16(2):e0247079 2021
Author:Yasukawa, Koya; Shimizu, Akira; Motoyama, Hiroaki; Kubota, Koji; Notake, Tsuyoshi; Sugenoya, Shinsuke; Hosoda, Kiyotaka; Hayashi, Hikaru; Kobayashi, Ryoichiro; Soejima, Yuji;

Usefulness and limitation of indocyanine green fluorescence for detection of peritoneal recurrence after hepatectomy for hepatocellular carcinoma: a case report
BMC SURGERY,21(1):107 2021
Author:Hayashi, Hikaru; Shimizu, Akira; Motoyama, Hiroaki; Kubota, Koji; Notake, Tsuyoshi; Sugenoya, Shinsuke; Hosoda, Kiyotaka; Yasukawa, Koya; Kobayashi, Ryoichiro; Soejima, Yuji;
Keywords:Hepatocellular carcinoma; Peritoneal dissemination; Indocyanine green fluorescence;

Treatment Strategy for Pancreatic Neuroendocrine Neoplasms (pNEN)
信州医学雑誌,68(5):235-242 2020(Oct. 10)
Author:Kubota, Koji; Shimizu, Akira; Notake, Tsuyoshi; Sugenoya, Shinsuke; Hosoda, Kiyotaka; Yasukawa, Koya; Hayashi, Hikaru; Kobayashi, Ryoichiro; Soejima, Yuji

Correlation of clinicopathological features and leucine-rich repeat-containing G-protein-coupled receptor 5 expression in pancreatic ductal adenocarcinoma.
Pathol Res Pract.,215(11):152623 2019(Nov.)
Author:Kuraishi Y, Uehara T, Kobayashi Y, Nakajima T, Watanabe T, Shimizu A, Ota H, Tanaka E.

Impact of age on groin hernia profiles observed during laparoscopic transabdominal preperitoneal hernia repair.
Surg Endosc.,33(8):2602-2611 2019(Aug.)
Author:Fukushima K, Yokoyama T, Miwa S, Motoyama H, Arai T, Kitagawa N, Shimizu A, Notake T, Kikuchi T, Kobayashi A, Miyagawa SI.

Treatment with specific soluble factors promotes the functional maturation of transcription factor-mediated, pancreatic transdifferentiated cells.
PLoS One.,13(5):e0197175 2018(May)
Author:Motoyama H, Kobayashi A, Yokoyama T, Shimizu A, Sakai H, Notake T, Fukushima K, Miyagawa SI.

Nomogram predicting long-term survival after the diagnosis of intrahepatic recurrence of hepatocellular carcinoma following an initial liver resection.
Int J Clin Oncol,22(4):715-725 2017(Aug.)
Author:Notake T, Kobayashi A, Shinkawa H, Kawahara T, Shimizu A, Yokoyama T, Hasegawa K, Kokudo N, Matsuyama Y, Makuuchi M, Miyagawa SI.

Survival Benefits of Surgical Resection in Patients with Recurrent Biliary Tract Carcinoma.
World J Surg,:in press 2017(Jul.)
Author:Motoyama H, Kobayashi A, Yokoyama T, Shimizu A, Kitagawa N, Notake T, Fukushima K, Masuo H, Yoshizawa T, Miyagawa SI.

Adjuvant Chemotherapy with Gemcitabine for Resected Biliary Tract Cancer: A Single-Arm Phase 2 Study
信州医学雑誌,65(2):99-111 2017(Apr. 10)
Author:Kitagawa, Noriyuki; Motoyama, Hiroaki; Kobayashi, Akira; Yokoyama, Takahide; Shimizu, Akira; Notake, Tsuyoshi; Fukushima, Kentaro; Masuo, Hitoshi; Yoshizawa, Takahiro; Tsukahara, Teruomi; Miyagawa, Shin-ichi

Correlation between the serum levels of type IV collagen 7s domain and the risk of intractable ascites following liver resection for hepatocellular carcinoma: A propensity score-matched analysis.
Surgery,160(5):1244-1255 2016(Nov.)
Author:Shimizu A, Kobayashi A, Yokoyama T, Motoyama H, Sakai H, Kitagawa N, Notake T, Shirota T, Fukushima K, Miyagawa SI.

Neuroendocrine tumor of the common bile duct.
Surgery,160(2):525-6 2016(Aug.)
Author:Hosoda K, Kobayashi A, Shimizu A, Kitagawa N, Ito T, Yamada A, Miyagawa S.

Contrast-enhancement ratio on multiphase enhanced computed tomography predicts recurrence of pancreatic neuroendocrine tumor after curative resection.
Pancreatology,16(3):397-402 2016(May)
Author:Arai T, Kobayashi A, Fujinaga Y, Yokoyama T, Shimizu A, Motoyama H, Kitagawa N, Notake T, Shirota T, Fukushima K, Masuo H, Kadoya M, Miyagawa S.

Features of acute liver congestion on gadoxetate disodium-enhanced MRI in a rat model: Role of organic anion-transporting polypeptide 1A1
JOURNAL OF MAGNETIC RESONANCE IMAGING,42(3):828-836 2015(Sep.)
Author:Shimizu, Akira; Kobayashi, Akira; Motoyama, Hiroaki; Sakai, Hiroshi; Yamada, Akira; Yoshizawa, Akihiko; Momose, Masanobu; Kadoya, Masumi; Miyagawa, Shin-ichi;

Biliary tract variations of the left liver with special reference to the left medial sectional bile duct in 500 patients
AMERICAN JOURNAL OF SURGERY,210(2):351-356 2015(Aug.)
Author:Furusawa, Norihiko; Kobayashi, Akira; Yokoyama, Takahide; Shimizu, Akira; Motoyama, Hiroaki; Kanai, Keita; Arakura, Norikazu; Yamada, Akira; Kitou, Yoshihiro; Miyagawa, Shin-ichi;

Effect of Application of Subcutaneous Suction Drainage with Subcuticular Sutures for Wound Closure on the Incidence of Incisional Surgical Site Infection following Elective General Abdominal Surgery : A Randomized Controlled Trial
信州医学雑誌,63(2):91-101 2015(Apr. 10)
Author:SHIMIZU, Akira; KOBAYASHI, Akira; KOIDE, Naohiko; SUZUKI, Akira; TAKEUCHI, Daisuke; YOKOYAMA, Takahide; MOTOYAMA, Hiroaki; FURUSAWA, Norihiko; TSUKAHARA, Teruomi; MIYAGAWA, Shin-ichi

Impact of advanced age on the short- and long-term outcomes in patients undergoing hepatectomy for hepatocellular carcinoma: a single-center analysis over a 20-year period
AMERICAN JOURNAL OF SURGERY,209(4):733-741 2015(Apr.)
Author:Motoyama, Hiroaki; Kobayashi, Akira; Yokoyama, Takahide; Shimizu, Akira; Sakai, Hiroshi; Furusawa, Norihiko; Notake, Tsuyoshi; Kitagawa, Noriyuki; Arai, Takuma; Yokoi, Kenta; Okubo, Yohei; Miyagawa, Shin-ichi;

An Initial Case Report of a Laparoscopic Spleen-Preserving Distal Pancreatectomy for a Patent with a Pancreatic Metastasis of Malignant Melanoma
The Shinshu Medical Journal,63(1):19-24 2015(Feb.)
Author:MOTOYAMA Hiroaki, KOBAYASHI Akira, YOKOYAMA Takahide, SHIMIZU Akira, FURUSAWA Norihiko, SAKAI Hiroshi, KITAGAWA Noriyuki, ASHIDA Atsuko, OKUYAMA Ryuhei, MIYAGAWA Shin-ichi

Laparoscopic Splenectomy Using a Low-pressure Pneumoperitoneum for the Treatment of Immune Thrombocytopenic Purpura During Pregnancy : A Case Report
The Shinshu Medical Journal,62(6):441-446 2014(Dec.)
Author:KUBOTA Koji, KOBAYASHI Akira, YOKOYAMA Takahide, KIKUCHI Norihiko, KITAGAWA Noriyuki, FURUSAWA Norihiko, MOTOYAMA Hiroaki, SHIMIZU Akira, SHIOZAWA Tanri, MIYAGAWA Shin-ichi

Liver failure after hepatocellular carcinoma surgery
LANGENBECKS ARCHIVES OF SURGERY,399(8):1047-1055 2014(Dec.)
Author:Motoyama, Hiroaki; Kobayashi, Akira; Yokoyama, Takahide; Shimizu, Akira; Furusawa, Norihiko; Sakai, Hiroshi; Kitagawa, Noriyuki; Ohkubo, Yohei; Tsukahara, Teruomi; Miyagawa, Shin-ichi;

Surgical Treatment of 144 Cases of Hilar Cholangiocarcinoma Without Liver-Related Mortality
WORLD JOURNAL OF SURGERY,38(5):1164-1176 2014(May)
Author:Furusawa, Norihiko; Kobayashi, Akira; Yokoyama, Takahide; Shimizu, Akira; Motoyama, Hiroaki; Miyagawa, Sin-ichi;

【学んでおくべき下大静脈関連手術】主肝静脈再建を伴う肝切除
手術,67(13):1819-1824 2013
Author:小林聡，清水明，宮川眞一

肝S7,8の病変を有する大腸癌同時性肝転移における用手補助腹腔鏡下肝切除術
日本内視鏡外科学会雑誌,18:737-743 2013
Author:酒井宏司，小林聡，横山隆秀，清水明，本山博章，宮川眞一

Hepatectomy preserving drainage veins of the posterior section for liver malignancy invading the right hepatic vein: an alternative to right hepatectomy
AMERICAN JOURNAL OF SURGERY,204(5):717-723 2012(Nov.)
Author:Shimizu, Akira; Kobayashi, Akira; Yokoyama, Takahide; Nakata, Takenari; Motoyama, Hiroaki; Kubota, Koji; Furusawa, Norihiko; Kitahara, Hiroe; Kitagawa, Noriyuki; Fukushima, Kentaro; Shirota, Tomoki; Miyagawa, Shinichi;

Role of bone marrow cells in the development of pancreatic fibrosis in a rat model of pancreatitis induced by a choline-deficient/ethionine-supplemented diet
Biochem Biophys Res Commun.,420(4):743-9 2012
Author:Akita S, Kubota K, Kobayashi A, Misawa R, Shimizu A, Nakata T, Yokoyama T, Takahashi M, Miyagawa S

Identification of oligopeptide binding to colon cancer cells separated from patients using laser capture microdissection
JOURNAL OF DRUG TARGETING,16(5):396-404 2008
Author:Kubo, Naoki; Akita, Noriyuki; Shimizu, Akira; Kitahara, Hiroe; Parker, Alan L.; Miyagawa, Shinichi;

Identification of an oligopeptide binding to hepatocellular carcinoma
ONCOLOGY,71(1-2):136-145 2006
Author:Shimizu, Akira; Maruta, Fukuto; Akita, Noriyuki; Miwa, Shiro; Seymour, Leonard W.; Kerr, David J.; Parker, Alan L.; Miyagawa, Shinichi;

Presentations
Hepatic venous reconstruction after concomitant resection for colorectal liver metastases and preoperative evaluation of hepatic venous drainage area
21st World Congress of the IASGO 2011(Nov. 10)
Presenter:Akira Shimizu, Akira Kobayashi, Tomoki Shirota, Kentaro Fukushima, Norihiko Furusawa, Hiroe Kitahara, Koji Kubota, Hiroaki Motoyama, Takenari Nakata, Takahide Yokoyama, Shinichi Miyagawa

TAPP法による鼠径部ヘルニア手術の利点と欠点
第9回日本ヘルニア学会学術集会 2011(Aug. 01)
Presenter:清水　明，横山隆秀，代田智樹，福島健太郎，北原弘恵，古澤徳彦，窪田晃治，本山博章，鈴木史恭，中田岳成，小林　聡，宮川眞一

大腸癌肝転移に対する複数肝静脈合併肝切除と肝静脈還流領域の術前評価
第66回日本消化器外科学会総会 2011(Jul. 13)
Presenter:清水　明，小林　聡，代田智樹，福島健太郎，北原弘恵，古澤徳彦，窪田晃治，本山博章，鈴木史恭，中田岳成，横山隆秀，宮川眞一

大腸癌肝転移に対する肝静脈合併肝切除と術前シミュレーション
第23回日本肝胆膵外科学会・学術集会 2011(Jun. 08)
Presenter:清水　明，小林　聡，北原弘恵，古澤徳彦，本山博章，窪田晃治，鈴木史恭，中田岳成，横山隆秀，宮川眞一

Research Grants: Grants‐in‐aid for Scientific Research(Research Representative)
2017 - 2019 , ALPPS手術後肝再生促進因子の同定と機能解析 , 基盤研究(C)

Shinshu University Researcher Directory

SHIMIZU Akira

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SHIMIZU　Akira