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Morita Hiroshi

Academic OrganizationAcademic Assembly School of Medicine and Health Sciences Institute of MedicineTEL
Education and Research OrganizationCenter for Health, Safety and Environmental ManagementFAX
PositionProfessorMail Address
AddressWeb sitehttp://jimuwww.shinshu-u.ac.jp/swd/health/

Modified:07/12/2023

Profile

Assigned Class
University Hospital, Department of Medicine (Neurology & Rheumatology)
Research Field
Clinical Neurophysiology
Medical Education
Current Subject
Motor control
Keywords:H reflex , Transcranial magnetic stimulation , Parkinson's disease , Spasticity
Professionalism education
Keywords:Professionalism
Academic Societies
Academic Societies
International Parkinson and Movement Disorder Society
Society for Neuroscience
Academic Background
Graduate School
Shinshu University , (Graduate School, Division of Medicine) , 1993

College
Shinshu University , (Faculty of Medicine) , 1986

Degree
PhD , Shinshu University
Research Career
Research Career
2017- , Professor, Center for Health, Safety and Enviromental Management
2013-2017 , Director,Clinical Professor, Clinical Residency Training Center
2008-2013 , Shinshu University Hospital, Associate Professor
2002-2008 , Shinshu University Hospital Dept of Medicine Lecturer
1994-2002 , Shinshu University Hospital Dept of Medicine Assistant

Other Career
1993-1994 , Nagano National Hospital Physician

Overseas Education
1996-1998 , Physiologisches Institute, Christian-Albrecht University (Kiel)
1995-1998 , Division of Neurophysiology, Department of Medical Physiology, The Panum Institute, Copenhagen University (Guest Scientist)

Research

Books, Articles, etc.
Books
The role of ceruloplasmin for iron and copper metabolism in central nervous system disorders, 405-411
1997
Author:Morita H/ Yanagisawa N/ Yasui M/ Strong MJ/ Ota K


Articles
Analysis of Suicide Cases among University Students: Comparison between Shinshu University and other universities
CAMPUS HEALTH,59(2):50-56 2022
Author:Isamu YAMAZAKI, Mayuko TOKUNAGA, Mihoko KANAI, Toshihide YAMAOKA, Akiko MORIMITSU, Akira YAMAZAKI, Tohru TAKAHASHI, Tomone TAKAHASHI, Hiroshi MORITA


Effect of biological factors on latency of pattern-reversal visual evoked potentials associated with cathode ray tubes and liquid crystal display monitors in normal young subjects.
Documenta Ophthalmologica,143(2):185-192 2021
Author:Ura M, Matsuo M, Yamazaki H, Morita H


Electrophysiological demyelinating features in hereditary ATTR amyloidosis.
Amyloid The Journal of Protein Folding Disorders,26(1):15-23 2019
Author:Ohashi N, Kodaira M, Morita H, Sekijima Y


Length-dependent truncal A-fiber dysfunction in hereditary transthyretin amyloidosis: An intra-epidermal electrical stimulation study.
Clinical Neurophysiology,130(6):903-910 2019
Author:Kodaira M, Ohashi N, Morita H, Sekijima Y.


Recruitment gain of spinal motor neuron pools in cat and human
Experimental Brain Research,237(11):2897-2909 2019
Author:Nielsen JB, Morita H, Wenzelburger R, Deuschl G, Gossartd J-P, Hultborn H.


Association between long work hours and depressive state: a pilot study of propensity score matched Japanese white-collar workers.
Industrial Health,56(3):207-211 2018(Jun. 01)
Author:Uchida M, Morita H


Natural history of spinocerebellar ataxia type 31: a 4-year prospective study.
Cerebellum,16:518-524 2017
Author:Nakamura K, Yoshida K, Matsushima A, Shimizu Y, Sato S, Yahikozawa H, Ohara S, Yazawa M, Ushiyama M, Sato M, Morita H, Inoue A, Ikeda S


Effects of tafamidis treatment on transthyretin (TTR) stabilization, efficacy, and safety in Japanese patients with familial amyloid polyneuropathy (TTR-FAP) with Val30Met and non-Varl30Met: A phase III, open-label study.
Journal of the Neurological Sciences,362:266-271 2016
Author:Ando Y, Sekijima Y, Obayashi K, Yamashita T, Ueda M, Misumi Y, Morita H, Machii K, Ohta M, Takata A, Ikeda S.


Safety and efficacy of long-term diflunisal administration in hereditary transthyretin (ATTR) amyloidosis
Amyloid,22(2):79-83 2015
Author:Sekijima Y, Tojo K, Morita H, Koyama J, Ikeda S


Inadequate modulation of excitability with voluntary dorsiflexion in Parkinson’s disease
Journal of Clinical Neurophysiology,31:175-179 2014
Author:Morita H, Kodaira M, Ikeda S


Giant cauda equina schwannoma
Journal of Neurology and Clinical Neuroscience,1(1):42-43 2013
Author:Morita H, Ito K, Miyazaki D, Fukushima K, Iwaya M, Hongo K, Ikeda S.


Intravenous immunoglobulin (IVIg) with methylprednisolone pulse therapy for motor impairment of neuralgic amyotrophy: clinical observations in 10 cases.
Internal Medicine,51(12):1493-1450 2012
Author:Naito KS, Fukushima K, Suzuki S, Kuwahara M, Morita H, Kusunoki S, Ikeda S.


Extensive brain pathology in a patient with aceruloplasminemia with a prolonged duration of illness.
Hum Pathol,43:451-456 2012
Author:Kaneko K, Hineno A, Yoshida K, Ohara S, Morita H, Ikeda SI.


Peripheral nerve involvement in primary systemic AL amyloidosis: a clinical and electrophysiological study
Eur J Neurol,18(4):604-610 2011(Apr.)
Author:Matsuda M, Gono T, Morita H, Katoh N, Kodaira M, Ikeda S


Exome sequencing reveals a homozygous SYT14 mutation in adult-onset, autosomal-recessive spinocerebellar ataxia with psychomotor retardation.
Am J Hum Genet,89(2):320-327 2011
Author:Doi H, Yoshida K, Yasuda T, Fukuda M, Fukuda Y, Morita H, Ikeda S, Kato R, Tsurusaki Y, Miyake N, Saitsu H, Sakai H, Miyatake S, Shiina M, Nukina N, Koyano S, Tsuji S, Kuroiwa Y, Matsumoto N.


Electrophysiological features of familial amyloid polyneuropathy in endemic area.
Amyloid,18:10-18 2011
Author:Kodaira M, Morita H, Shimojima Y, Ikeda S.


A young man with anti-NMDA encephalitis following Guillain-Barré syndrome.
Case Reports in Neurology,3:7-13 2011
Author:Tojo K, Nitta K,Ishii W, Sekijima Y, Morita H, Takahashi Y, Tanaka K, Ikeda S


Adult or late-onset triple A syndrome: case report and literature review.
Journal of the Neurological Sciences,297(1-2):85-88 2010
Author:Nakamura K, Yoshida K, Yoshinaga T, Kodaira M, Shimojima Y, Takei Y, Morita H, Kayanuma K, Ikeda S


Analysis of an insertion mutation in a cohort of 94 patients with spinocerebeller ataxia type 31 from Nagano, Japan
Neurogenetics,11(4):409-415 2010
Author:Sakai H, Yoshida K, Shimizu Y, Morita H, Ikeda S, Matsumoto N


Upper limb neuropathy such as carpal tunnel syndrome as an initial manifestation of ATTR Val30Met familial amyloid polyneuropathy
Amyloid,17(1):32-35 2010
Author:Tojo K, Tsuchiya-Suzuki A, Sekijima Y, Morita H, Sumita N, Ikeda S


Successful treatment with rituximab ina patient with stiff-person syndrome complicated by dysthyroid ophthalmopathy.
Internal Medicine,49(3):237-241 2010
Author:Katoh N, Matsuda M, Ishii W, Morita H, Ikeda S


Primary AL amyloid polyneuropathy successfully treated with high-dose melphalan followed by autologous stem cell transplantation
Muscle and Nerve,41:138-143 2010
Author:Katoh N, Matsuda M, Yoshida T, Yazaki M, Morita H, Sakashita K, Ikeda S.


The safety of transcranial magnetic stimulation with deep brain stimulation instruments
Parkinsonism and Related Disorders,16(2):127-131 2010
Author:Shimojima Y, Morita H, Nishikawa N, Kodaira M, Hashimoto T, IkedaSI.


Severity and progression rate of cerebellar ataxia in 16q-linked autosomal dominant cerebellar ataxia (16q-ADCA) in the endemic Nagano area of Japan
,8:46-51 2009
Author:Yoshida K, Shimizu Y, Morita H, Okano T, Sakai H, Ohata T, Matsumoto N, Nakamura K, Tazawa K, OharaS, Tabata K,Inoue A, Sato S, Shimojima Y, Hattori T, Ushiyama M, Ikeda S.


Spinocerebellar ataxia type 6 (SCA6):Clinical pilot trial with gabapentin.
Journal of the Neurological Sciences,278:107-111 2009
Author:Nakamura K, Yoshida K, Miyazaki D, Morita H, Ikeda S.


Spinal nerve root hypertrophy on MRI: clinical significance in the diagnosis of chronic inflammatory demyelinating polyradiculoneuropathy.
,47(23):2019-2024 2008
Author:Tazawa K, Matsuda M, Yoshida T, Shimojima Y, Gono T, Morita H, Kaneko T, Ueda H, Ikeda S.


Reversible extensive leukoencephalopathy in Sweet disease: A case report.
Journal of the Neurological Sciences,275:178-180 2008
Author:Fukushima K, Hineno A, Kodaira M, Machida K, Ishii W, Kaneko T, Shimojo H, Uhara H, Yamamoto K, Morita H, Yoshida K, Ikeda S.


Ten-year follow-up of peripheral nerve function in patients with familial amyloid polyneuropathy after liver transplantation.
J Neurology,255:12220-1225 2008
Author:Shimojima Y, Morita H, Kobayashi S, Takei Y, Ikeda S.


Size variance of motor evoked potential at initiation of voluntary contraction in palsy of conversion disorder
PSYCHIATRY AND CLINICAL NEUROSCIENCES,62(3):286-292 2008
Author:Morita, H; Shimojima, Y; Nishikawa, N; Hagiwara, N; Amano, N; Ikeda, SI


Severe cranial nerve involvement in a patient with monoclonal anti-MAG/SGPG IgM antibody and localized hard palate amyloidosis
JOURNAL OF THE NEUROLOGICAL SCIENCES,244(1-2):167-171 2006
Author:Yoshida, T; Yazaki, M; Gono, T; Tazawa, K; Morita, H; Matsuda, M; Funakoshi, K; Yuki, N; Ikeda, S


Sarin experiences in Japan: Acute toxicity and long-term effects
JOURNAL OF THE NEUROLOGICAL SCIENCES,249(1):76-85 2006
Author:Yanagisawa, N; Morita,H; Nakajima, T


Rituximab therapy in chronic inflammatory demyelinating polyradiculoneuropathy with anti-SGPG IgM antibody
JOURNAL OF CLINICAL NEUROSCIENCE,13(6):683-687 2006
Author:Gono, T; Matsuda, M; Shimojima, Y; Ishii, W; Yamamoto, K; Morita, H; Hashimoto, T; Susuki, K; Yuki, N; Ikeda, S


Lack of modulation of Ib inhibition during antagonist contraction in spasticity
NEUROLOGY,67(1):52-56 2006
Author:Morita, H; Shindo, M; Momoi,H; Yanagawa, S; Ikeda, S; Yanagisawa, N


A Japanese case of SCA14 withthe Gly128Asp mutation
JOURNAL OF HUMAN GENETICS,51(12):1118-1121 2006
Author:Morita, H; Yoshida, K; Suzuki, K; Ikeda, S


Paradoxical modulation of tendon tap reflex during voluntary contraction in Parkinson’s disease
Clin Neurophysiol,116(4):769-774 2005
Author:Morita H, ShindoM, Ikeda S


On the errors in assessment of severity of involuntary movements using surface EMG
J Electromyogr Kinesiol,15:316-322 2005
Author:Hashimoto T, Shindo M, Morita H, Yanagisawa N, Ikeda S


Increase in incidence of elderly-onset patients with myasthenia gravis in Nagano prefecture, Japan
Intern Med,44:572-577 2005
Author:Matsuda M, Dohi-Iijima N, Nakamura A, Sekijima Y, Morita H, Matsuzawa S, Sato S, Yahikozawa H, Tabata K, Yanagawa S, Ikeda S


Chemical terrorism: Long term neurobehavioral effects
JOURNAL OF THE NEUROLOGICAL SCIENCES,238:S9-S9 2005
Author:Yanagisawa, N; Morita, H; Nakajima, T


Characteristic spinal MRI findings of HIV-associated myelopathy in an AIDSpatient
Intern Med,44:763-764 2005
Author:Shimojima Y, Yazaki M, Kaneko K, Fukushima K, Morita H, Hashimoto T, Ikeda S


Retrospective analyses of clinical features and therapeutic outcomes in thymectomized patients with myasthenia gravis at Shinshu University
Intern Med,43:189-193 2004
Author:Dohi-Iijima N, Sekijima Y, Nakamura A, Morita H, Matsuda M, Haniuda M, Hashimoto T, Ikeda S


Cyclosporin A in treatment of refractory patients with chronic inflammatory demyelinating polyradiculoneuropathy
J Neurol Sci,224:29-35 2004
Author:Matsuda M, HoshiK, Gono T, Morita H, Ikeda S


Peripheral nerve function in patients with familial amyloid polyneuropathy after liver transplantation
AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS,10(1):17-24 2003
Author:Kobayashi, S; Morita, H; Asawa, T; Takei, Y; Hashimoto, T; Ikegami, T; Hashikura, Y; Kawasaki, S; Ikeda, S


Long-term follow-up of systemic reactive AA amyloidosis secondary to rheumatoid arthritis : successful treatment with intermediate-dose corticosteroid
Internal Med,41(5):403-407 2002
Author:Matsuda M, Morita H, Ikeda S


Interaction between peripheral afferent activity and presynaptic inhibition of Ia afferents in the cat
J Neurophysiol,88:1664-1674 2002
Author:Enriquez-Denton M, Morita H, Christensen L.O.D, Petersen N, Sinkjaer T, Nielsen J. B


Abnormal conditioning effect of transcranial magnetic stimulation on soleus H-reflex during voluntary movement in Parkinson's disease
Clinical Neurophysiology,113(8):1316-1324 2002
Author:Morita H, Shindo M, Morita S, Hashimoto T, Tada T, Ikeda S.


Plasma levels of amyloid beta proteins did not differ between subjects taking statins and those not taking statins
ANNALS OF NEUROLOGY,49(4):546-547 2001
Author:Tokuda, T; Tamaoka, A; Matsuno, S; Sakurai, S; Shimada, H; Morita, H; Ikeda, S


Neurophysiological evaluation of peripheral nerve function in patients with FAP after liver transplantation
AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS,8:111-112 2001
Author:Morita, H; Kobayashi, S; Takei, Y; Hattori, T; Hashimoto, T; Ikeda, S


Neuronal activity in the globus pallidus in chorea caused by striatal lacunar infarction
ANNALS OF NEUROLOGY,50(4):528-531 2001
Author:Hashimoto, T; Morita, H; Tada, T; Maruyama, T; Yamada, Y; Ikeda, S


Modulation of presynaptic and disynaptic Ia inhibition during voluntary movements in spasticity
Brain,124:826-837 2001
Author:Morita H, Crone C et at.


Life-threatening orthostatic hypotension in a case withbulbo-myelo-radiculo-neuropathy
AUTONOMIC NEUROSCIENCE-BASIC&CLINICAL,94(1-2):125-131 2001
Author:Ishikawa, S; Hattori, T; Takei, Y; Morita, H; Yazaki, M; Nakamura, A; Ikeda, S


Successful treatment with alpha-interferon of a patient with chronic measles infection of the brain and parkinsonism
European Neurology,44(3):184-186 2000
Author:Yazaki M, Yamazaki M, Urasawa N, Morita H, Ikeda S


Simultaneous exacerbation and remission of central and peripheral demyelination
Muscle and Nerve,23(3):440-441 2000
Author:Sato S, Nakamura A, Iwahashi T, Morita H, Hashimoto T, Ikeda S


Presynaptic control of transmission along the pathway mediating disynaptic reciprocal inhibition in the cat.
Journal of Physiology,526:623-637 2000
Author:Enriquez-Denton M, Nielsen J, Perreault MC, Morita H, Petersen N, Hultborn H


Differential changes in corticospinal and Ia input to tibialis anteriorand soleus motor neurones during voluntary contraction in man
Acta Physiol Scand,170(1):65-76 2000
Author:Morita H et al.


Decrease in presynaptic inhibition on heteronymous monosynaptic Ia terminals in patients with Parkinson's disease
Movement Disorders,15(5):830-834 2000
Author:Morita H, Shindo M et al.


A case of pectoral fasciitis with spontaneous remission
European Neurology,44(2):124-125 2000
Author:Fushimi T, Nakamura A, Yazaki M, Shimizu Y, Morita H, Ikeda S


Recruitment of extensor carpi radialis motor units by transcranial magnetic stimulation and radial nerve stimulation in human subjects
Exp Brain Res,128:557-562 1999
Author:Morita H Shindo M et al.


Modulation of reciprocal inhibition between ankle extensors and flexors during walking in man
Journal of Physiology,520:605-619 1999
Author:Petersen N, Morita H, Nielsen J


Sleep apnoea of central origin in a case of myotonic dystrophy
JOURNAL OF CLINICAL NEUROSCIENCE,5(1):112-115 1998
Author:Sekijima, Y; Morita, H; Hashimoto, T; Yamazaki, M; Yanagisawa, N


Urinary metabolites of sarin in a patient of the Matsumoto sarin incident
ARCHIVES OF TOXICOLOGY,72(9):601-603 1998
Author:Nakajima, T; Sasaki, K; Ozawa, H; Sekijima, Y; Morita, H; Fukushima, Y; Yanagisawa, N


Sensitivity of H-reflexes and stretch reflexes to presynaptic inhibition in humans
J Neurophysiol,80:610-620 1998
Author:Morita H et al.


Unexpected nerve gas exposure in the city of Matsumoto: Report of rescue activity in the first sarin gas terrorism
AMERICAN JOURNAL OF EMERGENCY MEDICINE,15(5):527-528 1997
Author:Okudera, H; Morita, H; Iwashita, T; Shibata, T; Otagiri, T; Kobayashi, S; Yanagisawa, N


Sarin poisoning of a rescue team in the Matsumoto sarin incident in Japan
OCCUPATIONAL AND ENVIRONMENTAL MEDICINE,54(10):697-701 1997
Author:Nakajima, T; Sato, S; Morita, H; Yanagisawa, N


Follow-up of sarin poisoning in Matsumoto
ANNALS OF INTERNAL MEDICINE,127(11):1042-1042 1997
Author:Sekijima, Y; Morita, H; Yanagisawa, N


Inhibitory projection from brachioradialis to biceps brachii motoneurones in human
EXPERIMENTAL BRAIN RESEARCH,111(3):483-486 1996
Author:Naito, A; Shindo, M; Miyasaka, T; Sun, YJ; Morita, H


A MUTATION IN THE CERULOPLASMIN GENE IS ASSOCIATED WITH SYSTEMIC HEMOSIDEROSIS IN HUMANS
NATURE GENETICS,9(3):267-272 1995
Author:YOSHIDA, K; FURIHATA, K; TAKEDA, S; NAKAMURA, A; YAMAMOTO, K; MORITA, H; HIYAMUTA, S; IKEDA, S; SHIMIZU, N; YANAGISAWA, N


INCREASE IN RECIPROCAL IA INHIBITION DURING ANTAGONIST CONTRACTION IN THE HUMAN LEG - A STUDY OF MOTOR UNITS AND THE H-REFLEX
JOURNAL OF PHYSIOLOGY-LONDON,489(1):275-285 1995
Author:SHINDO, M; YANAGAWA, S; MORITA, H; YANAGISAWA, N


Sarin poisoning in Matsumoto, Japan
Lancet,346(8970):290-293 1995
Author:Morita H et al.


Progressive decrease in heteronymous monosynaptic la facilitation with human ageing
Exp Brain Res,104(1):167-170 1995
Author:Morita H et al.


Hereditary ceruloplasmin deficiency with hemosiderosis: A clinicopathological study of a Japanese family
Ann Neurol,37(5):646-656 1995
Author:Morita H et al.


CONDITIONING EFFECT IN SINGLE HUMAN MOTONEURONS - A NEW METHOD USING THE UNITARY H-REFLEX
JOURNAL OF PHYSIOLOGY-LONDON,481(2):469-477 1994
Author:SHINDO, M; YANAGAWA, S; MORITA, H; HASHIMOTO, T


NEUROMUSCULAR RESPONSE IN MAN TO REPETITIVE NERVE-STIMULATION
MUSCLE&NERVE,16(6):648-654 1993
Author:MORITA, H; SHINDO, M; YANAGAWA, S; YANAGISAWA, N


SPINAL-CORD SARCOIDOSIS - MRI FINDINGS IN RESPONSE TO TREATMENT
EUROPEAN NEUROLOGY,32(3):126-129 1992
Author:MORITA, H; HAYASHI, R; TAKO, K; TSUKADA, N; YANAGISAWA, N


PROGRESSIVE SUPRANUCLEAR PALSY-LIKE SYNDROME IN 2 SIBLINGS OF A CONSANGUINEOUS MARRIAGE
NEUROLOGY,42(5):1009-1014 1992
Author:OHARA, S; KONDO, K; MORITA, H; MARUYAMA, K; IKEDA, S; YANAGISAWA, N


RIGID SPINE SYNDROME WITH RESPIRATORY-FAILURE
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY,53(9):782-784 1990
Author:MORITA, H; KONDO, K; HOSHINO, K; MARUYAMA, K; YANAGISAWA, N