伊藤 研一 (イトウ ケンイチ)
学術研究院（医学系）
医学部 医学科 外科学（乳腺内分泌外科学分野）
教授
研究者情報
経歴
研究活動情報
論文
- 著しい副甲状腺機能亢進を呈しながら術前画像診断が困難であった嚢胞性副甲状腺腺腫の１例
久保田 諭史, 島田 恭輔, 髙山 昇平, 大場 崇旦, 伊藤 研一, 駒津 光久
信州医学雑誌, 70(3), 189-194, 2022年06月
- Surgical resection of the primary tumor prevents an undesirable locoregional condition and improves the quality of life in patients with anaplastic thyroid cancer.
Kanai T, Ito T, Morikawa H, Amitani M, Shimizu T, Ohno K, Ono M, Oba T, Maeno K, Ito KI
Surg Today, 2022年 - Epidermal growth factor receptor activation confers resistance to lenvatinib in thyroid cancer cells.
Ohno K, Shibata T, Ito KI.
Cancer Science., 2022年 - Neutrophil-to-Lymphocyte Ratio Is Associated With the Proportion of Poorly Differentiated Components in Papillary Thyroid Carcinoma.
Oba T, Kazuma M, Kiyosawa N, Morikawa H, Amitani M, Chino T, Shimizu T, Ono M, Ito T, Kanai T, Ito KI.
J Surg Res., 2022年 - Hypercalcemic crisis caused by primary hyperparathyroidism in a 11-year-old boy: a rare case report and review of the literature
Hayashi S, Oba T, Ichikawa K, Nakamura C, Hara Y, Kanai T, Sato Y, Uehara T, Ito KI.
Gland Surgery, 2022年 - Skeletal muscle loss during neoadjuvant chemotherapy predicts poor prognosis in patients with breast cancer.
Amitani M, Oba T, Kiyosawa N, Morikawa H, Chino T, Soma A, Shimizu T, Ohno K, Ono M, Ito T, Kanai T, Maeno K, Ito KI.
BMC CANCER, 2022年 - The mechanisms involved in the resistance of estrogen receptor-positive breast cancer cells to palbociclib are multiple and change over time
Ono, Mayu; Oba, Takaaki; Shibata, Tomohiro; Ito, Ken-Ichi;
JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY, 147(11), 3211-3224, 2021年11月
- HDAC6 inhibition enhances the anti-tumor effect of eribulin through tubulin acetylation in triple-negative breast cancer cells
Oba, Takaaki; Ono, Mayu; Matoba, Hisanori; Uehara, Takeshi; Hasegawa, Yoshie; Ito, Ken-ichi;
BREAST CANCER RESEARCH AND TREATMENT, 186(1), 37-51, 2021年02月 - Concomitant use of F-18-FDG PET-CT SUVmax is useful in the assessment of Ki67 labeling index in core-needle biopsy specimens of breast cancer
Nakajima, Hiroki; Maeno, Kazuma; Ito, Tokiko; Kanai, Toshiharu; Oba, Takaaki; Ono, Mayu; Takayama, Fumiyoshi; Uehara, Tsuyoshi; Ito, Ken-ichi;
Gland Surgery, 10(1), 1-9, 2021年01月 - Prognostic Nutritional Index Is Superior to Neutrophil-to-lymphocyte Ratio as a Prognostic Marker in Metastatic Breast Cancer Patients Treated With Eribulin
Oba, Takaaki; Maeno, Kazuma; Ono, Mayu; Ito, Tokiko; Kanai, Toshiharu; Ito, Ken-ichi;
ANTICANCER RESEARCH, 41(1), 445-452, 2021年01月 - Tamoxifen resistance alters sensitivity to 5-fluorouracil in a subset of estrogen receptor-positive breast cancer
Watanabe, Takayuki; Oba, Takaaki; Tanimoto, Keiji; Shibata, Tomohiro; Kamijo, Shinobu; Ito, Ken-ichi;
PLOS ONE, 16(6), e0252822, 2021年 - 縦隔リンパ節転移の外科的治療
金井 敏晴;網谷 正統;清水 忠史;大野 晃一;小野 真由;大場 崇旦;伊藤 勅子;前野 一真;伊藤 研一
日本内分泌・甲状腺外科学会雑誌, 38(2), 63-67, 2021年 - Bone morphogenetic protein-7 expression reflects the high proliferative ability and aggressiveness of thymic epithelial tumors
Miura, Kentaro; Hamanaka, Kazutoshi; Uehara, Tsuyoshi; Momose, Masanobu; Kanai, Yukiko; Matsuoka, Shunichiro; Takeda, Tetsu; Agatsuma, Hiroyuki; Hyogotani, Akira; Ito, Ken-ichi;
JOURNAL OF THORACIC DISEASE, 12(3), 448-456, 2020年03月 - Neoadjuvant chemotherapy-induced decrease of prognostic nutrition index predicts poor prognosis in patients with breast cancer
Oba, Takaaki; Maeno, Kazuma; Takekoshi, Daiya; Ono, Mayu; Ito, Tokiko; Kanai, Toshiharu; Ito, Ken-ichi;
BMC CANCER, 20(1), 2020年 - Comparative efficacy and safety of tyrosine kinase inhibitors for thyroid cancer: a systematic review and meta-analysis
Oba, Takaaki; Chino, Tatsunori; Soma, Ai; Shimizu, Tadafumi; Ono, Mayu; Ito, Tokiko; Kanai, Toshiharu; Maeno, Kazuma; Ito, Ken-ichi;
Endocrine journal, 67(12), 1215-1226, 2020年 - 癌微小環境研究up-date(第5回)癌微小環境に基づいた乳癌治療
伊藤 研一
Cancer board of the breast = キャンサーボードオブザブレスト, 5(2), 102-104, 2019年09月 - 腹腔鏡下リスク低減卵管卵巣摘出術により両側卵管采に漿液性卵管上皮内病変が発見された遺伝性乳癌卵巣癌症候群の１例
鹿島 大靖, 岡 賢二, 品川 真奈花, 山中 桜, 小野 元紀, 竹内 穂高, 井田 耕一, 樋口 正太郎, 山田 靖, 小原 久典, 菊地 範彦, 宮本 強, 橘 涼太, 福嶋 義光, 古庄 知己, 家里 明日美, 伊藤 研一, 浅香 志穂, 上原 剛, 塩沢 丹里
信州医学雑誌, 67(3), 209-215, 2019年06月
- FGF2-FGFR1 pathway activation together with thymidylate synthase upregulation is induced in pemetrexed-resistant lung cancer cells
Miura K, Oba T, Hamanaka K, Ito K
Oncotarget, 10, 1171-1192, 2019年 - 甲状腺乳頭癌の再発リスク分類
金井敏晴、伊藤研一、千野辰徳、小野真由、大野晃一、伊藤勅子、前野一真
日本内分泌外科学会雑誌, 36(4), 209-212, 2019年 - 当科における甲状腺低分化癌の臨床的特徴と遠隔成績の検討
前野 一真;伊藤 研一;清水 忠史;相馬 藍;竹腰 大也;小野 真由;大場 崇旦;伊藤 勅子;金井 敏晴;上原 剛
日本内分泌・甲状腺外科学会雑誌, 36(4), 235-239, 2019年 - Lenvatinib(VEGFR阻害)の臨床試験と適正使用 (特集 頭頸部がん・甲状腺がん・希少がん) -- (甲状腺がん)
伊藤 研一;清水 忠史;相馬 藍;竹腰 大也;小野 真由;大場 崇旦;伊藤 勅子;金井 敏晴;前野 一真
腫瘍内科 = Clinical oncology, 22(4), 404-409, 2018年10月 - 肺癌術後肺炎に対する周術期口腔機能管理の有効性に関する後ろ向き観察研究
梶原 稜, 山田 慎一, 西牧 史洋, 近藤 英司, 鎌田 孝広, 小山 力, 松岡 峻一郎, 竹田 哲, 三浦 健太郎, 山田 響子, 濱中 一敏, 伊藤 研一, 栗田 浩
信州医学雑誌, 66(4), 249-256, 2018年08月 - レンバチニブ (特集 期待される新薬 : 分子標的治療薬の効果と副作用) -- (小分子薬)
伊藤 勅子;伊藤 研一
腫瘍内科 = Clinical oncology, 21(6), 675-682, 2018年06月 - Combination of two anti-tubulin agents, eribulin and paclitaxel, enhances anti-tumor effects on triple-negative breast cancer through mesenchymal-epithelial transition.
Oba T, Ito KI.
Oncotarget, 9(33), 22986-23002, 2018年05月 - Increased Expression of Y-Box-Binding Protein-1 in Hind-Limb Muscles During Regeneration from Ischemic Injury in Mice
Fuke, Megumi; Narita, Makoto; Wada, Yuko; Seto, Tatsuichiro; Okada, Kenji; Nakayama, Jun; Izumi, Hiroto; Ito, Ken-ichi;
TOHOKU JOURNAL OF EXPERIMENTAL MEDICINE, 244(1), 53-62, 2018年01月 - Analysis of surgical treatment of Masaoka stage III-IV thymic epithelial tumors.
Hamanaka K, Koyama T, Matsuoka S, Takeda T, Miura K, Yamada K, Hyogotani A, Seto T, Okada K, Ito KI.
Gen Thorac Cardiovasc Surg, in press, 2018年 - 術前化学療法中に扁平上皮癌成分の増大を生じた混合型乳腺扁平上皮癌の１例
金井 敏晴;大場 崇旦;伊藤 勅子;前野 一真;伊藤 研一;玉田 恒
日本内分泌・甲状腺外科学会雑誌, 35(4), 282-287, 2018年 - 初潮とともに急速増大した14歳乳腺線維腺腫の1例
池原 智彦;大場 崇旦;前野 一真;伊藤 研一;小林 翔;上原 剛
日本臨床外科学会雑誌, 79(6), 1187-1192, 2018年 - Chylous leakage after axillary lymph node dissection in a patient with breast cancer
Oba, Takaaki; Ono, Mayu; Iesato, Asumi; Hanamura, Toru; Watanabe, Takayuki; Ito, Tokiko; Kanai, Toshiharu; Maeno, Kazuma; Ito, Ken-ichi;
BREAST JOURNAL, 24(3), 438-440, 2018年 - A Case of Adenomyoepithelioma of the Breast Showing Strong Uptake of (18) F-Fluorodeoxyglucose on a Positron Emission Tomography.
Oba T, Maeno K, Ono M, Iesato A, Ito T, Kanai T, Mochizuki Y, Ito KI, Yoshizawa A, Takayama F.
Breast J, 23(2), 220-224, 2017年03月 - Case of painless thyroiditis that developed during adjuvant chemotherapy for breast cancer.
Iesato A, Oba T, Ono K, Watanabe T, Ito T, Kanai T, Maeno K, Ito K.
Int Cancer Conf J, 6(4), 184-187, 2017年 - PATZ1 knockdown enhances malignant phenotype in thyroid epithelial follicular cells and thyroid cancer cells
Iesato, Asumi; Nakamura, Teruo; Izumi, Hiroto; Uehara, Takeshi; Ito, Ken-Ichi;
Oncotarget, 8(47), 82754-82772, 2017年 - Human 3 beta-hydroxysteroid dehydrogenase type 1 in human breast cancer: clinical significance and prognostic associations
Hanamura, Toru; Ito, Tokiko; Kanai, Toshiharu; Maeno, Kazuma; Shimojo, Yasuyo; Uehara, Takeshi; Suzuki, Takashi; Hayashi, Shin-ichi; Ito, Ken-ichi;
CANCER MEDICINE, 5(7), 1405-1415, 2016年07月 - 女性のがん患者の生活・生命の質（QOL）の実態調査 : 術後1年間のQOL調査結果から
増樺京子, 竹内沙弥香, 所真由美, 執印抄枝子, 青柳美恵子, 伊藤勅子, 伊藤研一, 樋口正太郎, 塩沢丹里
信州大学医学部附属病院看護研究集録, 45(1), 1-6, 2016年03月 - Significance of sentinel lymph nodes with low gamma counts in breast cancer patients via radioisotopic sentinel lymph node biopsy
Maeno K, Ito T, Koyama H, Kanai T, Mochizuki Y, Ito K
Arch Surg Oncol, 2, 1, 2016年 - ABCB1 and ABCC11 confer resistance to eribulin in breast cancer cell lines
Oba, Takaaki; Izumi, Hiroto; Ito, Ken-ichi;
Oncotarget, 7(43), 70011-70027, 2016年 - Lipid-rich carcinoma of the breast that is strongly positive for estrogen receptor: a case report and literature review
Oba, Takaaki; Ono, Mayu; Iesato, Asumi; Hanamura, Toru; Watanabe, Takayuki; Ito, Tokiko; Kanai, Toshiharu; Maeno, Kazuma; Ito, Ken-ichi; Tateishi, Ayako; Yoshizawa, Akihiko; Takayama, Fumiyoshi;
OncoTargets and Therapy, 9, 1641-1646, 2016年 - Breast metastases of gastric signet-ring cell carcinoma: a report of two cases and review of the literature
Iesato, Asumi; Oba, Takaaki; Ono, Mayu; Hanamura, Toru; Watanabe, Takayuki; Ito, Tokiko; Kanai, Toshiharu; Maeno, Kazuma; Ishizaka, Katsuhiko; Kitabatake, Hiroyuki; Takeuchi, Daisuke; Suzuki, Akira; Nakayama, Jun; Ito, Ken-ichi;
OncoTargets and Therapy, 8, 91-97, 2015年 - Coexpression of EpCAM, CD44 Variant Isoforms and Claudin-7 in Anaplastic Thyroid Carcinoma
Okada, Toshihiro; Nakamura, Teruo; Watanabe, Takayuki; Onoda, Naoyoshi; Ashida, Atsuko; Okuyama, Ryuhei; Ito, Ken-ichi;
PLOS ONE, 9(4), e94487, 2014年 - Expression of Polypeptide N-Acetylgalactosaminyl Transferase-3 and Its Association with Clinicopathological Factors in Thyroid Carcinomas
Mochizuki, Yasuhiro; Ito, Ken-ichi; Izumi, Hiroto; Kohno, Kimitoshi; Amano, Jun;
THYROID, 23(12), 1553-1560, 2013年 - Rapid tumor necrosis and massive hemorrhage induced by bevacizumab and paclitaxel combination therapy in a case of advanced breast cancer
Ono, Mayu; Ito, Tokiko; Kanai, Toshiharu; Murayama, Koichi; Koyama, Hiroshi; Maeno, Kazuma; Mochizuki, Yasuhiro; Iesato, Asumi; Hanamura, Toru; Okada, Toshihiro; Watanabe, Takayuki; Ito, Ken-ichi;
OncoTargets and Therapy, 6, 1393-1398, 2013年 - Association of Nuclear YB-1 Localization With Lung Resistance-related Protein and Epidermal Growth Factor Receptor Expression in Lung Cancer
Hyogotani, Akira; Ito, Ken-ichi; Yoshida, Kazuo; Izumi, Hiroto; Kohno, Kimitoshi; Amano, Jun;
CLINICAL LUNG CANCER, 13(5), 375-384, 2012年09月 - Alteration of Y-box binding protein-1 expression modifies the response to endocrine therapy in estrogen receptor-positive breast cancer
Ito, Tokiko; Kamijo, Shinobu; Izumi, Hiroto; Kohno, Kimitoshi; Amano, Jun; Ito, Ken-ichi;
BREAST CANCER RESEARCH AND TREATMENT, 133(1), 145-159, 2012年05月 - Multimodality therapeutic outcomes In anaplastic thyroid carcinoma: Improved survival in subgroups of patients with localized primary tumors
Ito, Ken-ichi; Hanamura, Toru; Murayama, Koichi; Okada, Toshihiro; Watanabe, Takayuki; Harada, Michihiko; Ito, Tokiko; Koyama, Hiroshi; Kanai, Toshiharu; Maeno, Kazuma; Mochizuki, Yasuhiro; Amano, Jun;
HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK, 34(2), 230-237, 2012年02月 - Full-thickness chest-wall resection followed by thorax reconstruction for recurrent malignant phyllodes tumor
Ito, Tokiko; Ito, Ken-ichi; Okada, Toshihiro; Murayama, Koichi; Hanamura, Toru; Kanai, Toshiharu; Maeno, Kazuma; Mochizuki, Yasuhiro; Kondo, Ryoichi; Amano, Jun; Osada, Yoshiro; Asano, Koji;
International Journal of Clinical Oncology, 16(2), 156-160, 2011年04月 - Upregulation of the apoptosis-related inflammasome in cardiac allograft rejection
Seto, Tatsuichiro; Kamijo, Shinobu; Wada, Yuko; Yamaura, Kazuhiro; Takahashi, Kohei; Komatsu, Kazunori; Otsu, Yoshinori; Terasaki, Takamitsu; Fukui, Daisuke; Amano, Jun; Taniguchi, Shun'ichiro; Sagara, Junji; Ito, Ken-ichi;
JOURNAL OF HEART AND LUNG TRANSPLANTATION, 29(3), 352-359, 2010年03月 - ENDOSCOPIC-ASSISTED SKIN-SPARING MASTECTOMY COMBINED WITH SENTINEL NODE BIOPSY
Ito, Ken-Ichi; Kanai, Toshiharu; Gomi, Kuniyuki; Watanabe, Takayuki; Ito, Tokiko; Komatsu, Akira; Fujita, Tomoyuki; Amano, Jun;
ANZ JOURNAL OF SURGERY, 78(10), 894-898, 2008年10月 - Hepatocyte growth factor prevents pulmonary ischernia-reperfusion injury in mice
Makiuchi, Akiko; Yamaura, Kazuhiro; Mizuno, Shinya; Matsumoto, Kunio; Nakamura, Toshikazu; Amano, Jun; Ito, Ken-ichi;
JOURNAL OF HEART AND LUNG TRANSPLANTATION, 26(9), 935-943, 2007年09月 - Stimulation of P19CL6 with multiple reagents induces pulsating particles in vivo
Ohtsu Y, Johkura K, Ito K, Akashima T, Asanuma K, Ogiwara N, Oka T, Komuro I, Sasaki K, Amano J
CURRENT MEDICAL RESEARCH AND OPINION, 21(5), 795-803, 2005年 - Increased nuclear localization of transcription factor Y-box binding protein 1 accompanied by up-regulation of P-glycoprotein in breast cancer pretreated with paclitaxel
Fujita T, Ito K, Izumi H, Kimura M, Sano M, Nakagomi H, Maeno K, Hama Y, Shingu K, Tsuchiya S, Kohno K, Fujimori M
CLINICAL CANCER RESEARCH, 11(24), 8837-8844, 2005年 - Suppression of acute and chronic rejection by hepatocyte growth factor in a murine model of cardiac transplantation - Induction of tolerance and prevention of cardiac allograft vasculopathy
Yamaura, K; Ito, K; Tsukioka, K; Wada, Y; Makiuchi, A; Sakaguchi, M; Akashima, T; Fujimori, M; Sawa, Y; Morishita, R; Matsumoto, K; Nakamura, T; Suzuki, J; Amano, J; Isobe, M
Circulation, 110(12), 1650-1657, 2004年 - Mutation of proline residues in the NH2-terminal region of the multidrug resistance protein, MRP1(ABCC1): effects on protein expression, membrane localization, and transport function.
Ito K, Weigl LE, Deeley RG, Cole SPC.
Biochim Biophys Acta-Biomember1615, 103-114, 2003年 - Mutation of the class I beta-tubulin gene does not predict response to paclitaxel for breast cancer
Maeno K, Ito K, Hama Y, Shingu K, Kimura M, Sano M, Nakagomi H, Tsuchiya S, Fujimori M
CANCER LETTERS, 198(1), 89-97, 2003年 - Mutation of a Single Conserved Tryptophan in Multidrug Resistance Protein 1 (MRP1/ABCC1) Results in Loss of Drug Resistance and Selective Loss of Organic Anion Transport
K. Ito/ S. Cole
J. Biol. Chem, 276, 15616-15624, 2001年 - Mutation of Trp1254 in the multispecific organic anion transporter, MRP2 (ABCC2), alters substrate specificity and results in loss of methotrexate transport activity
Ito K, Oleschuk CJ, Westlake C, Vasa MZ, Deeley RG, Cole SPC
J. Biol. Chem, 276, 38108-38114, 2001年 - 上皮小体の位置診断における⁹⁹mTc MIBIシンチグラムの有用性 : 局在画像診断法の検討
中村 俊幸;小林 信や;藤森 実;新宮 聖士;伊藤 研一;浜 善久;天野 純;橋爪 潔志;伊藤 敦子;小松 誠;山岸 喜代文
信州医学雑誌, 46(5), 331-335, 1998年10月10日 - Clinical significance of the increased multidrug resistance-associated protein (MRP) gene expression in patients with primary breast cancer
K. Ito/ M. Fujimori/ J. Amano
Oncol Res, 10, 99-109, 1998年 - Expression of tissue-type plasminogen activator and its inhibitor couples with development of capillary network by human microvascular endothelial cells on Matrigel
Ito K, Ryuto M, Ushiro S, Ono M, Sugenoya A, Kuraoka A, Shibata Y, Kuwano M
J. Cell. Physiol, 162, 213-024, 1995年 - anti-angiogenic activity of arachidonic acid metabolism inhibitors in angiogenesis model systems involving human microvasucular endothelial cells and neovascularization in mice.
Ito k, Abe T, Tomita M, Morimoto A, Kohno K, Mori T, Ono M, Sugenoya A, Nishihira T, Kuwano M.
Int J Cancer, 55(4), 660-666, 1993年
共同研究・競争的資金等の研究課題
