信州大学HOMEENGLISH交通・キャンパス案内

研究者総覧研究者総覧

研究者、研究内容などで検索
項目別検索はこちら

野﨑功一  ノザキ コウイチ

教員組織学術研究院(工学系)電話番号026-269-5396
教育組織工学部 物質化学科FAX番号026-269-5396
職名准教授メールアドレスknoza@shinshu-u.ac.jp
住所〒380-8553 長野市若里4-17-1ホームページURLhttp://www.shinshu-u.ac.jp/faculty/engineering/chair/chem010/index.html

更新日:2020/07/09

プロフィール

兼担研究科・学部
大学院工学系研究科
大学院総合工学系研究科
研究分野
酵素化学,応用微生物学,遺伝子工学
現在の研究課題
糸状菌におけるバイオマス分解機構の解明とその応用
キーワード:セルロース分解系酵素
糸状菌におけるセルラーゼ誘導機構の解明
キーワード:酵素 , 遺伝子発現
バイオマスの有効利用に関する研究
キーワード:バイオマス分解
担子菌の生産するリグニン分解系酵素に関する研究
キーワード:白色腐朽菌 , リグニン分解系酵素
所属学会
所属学会
日本応用糖質科学会
日本農芸化学会
セルロース学会
日本生物工学会
糸状菌分子生物学研究会
学歴
出身大学院
1998 , 北海道大学大学院 , 農学研究科 , 博士後期課程
1995 , 弘前大学大学院 , 農学研究科 , 修士課程

出身学校・専攻等(大学院を除く)
1993 , 弘前大学 , 農学部

取得学位
博士(農学),北海道大学
受賞学術賞
2012 , 日本応用糖質科学会 奨励賞
2002 , セルラーゼ研究会 ポスター賞
研究職歴等
研究職歴
2005- , 信州大学 准教授
1999-2004 , 信州大学 助手

研究職歴以外の職歴
2007-2007 , 弘前大学 農学部 非常勤講師

留学歴
2007-2008 , ウィーン工科大学 化学工学研究所

研究活動業績

研究業績(著書・
発表論文等)
著書
バイオマス分解酵素研究の最前線ーセルラーゼ・ヘミセルラーゼを中心としてー 第1章 5. 担子菌 (Irpex lacteus) のセルラーゼ
シーエムシー出版 2012
Author:天野良彦,野﨑功一


論文
Orientation control of Trametes laccases on a carbon electrode surface to understand the orientation effect on the electrocatalytic activity
Bioconjug Chem 2018
Author:Hoshikawa Y, Castro-Muñiz A, Tawata H, Nozaki K, Yamane S, Itoh T, Kyotani T


Comparison of catalytic properties of multiple β-glucosidases of Trichoderma reesei
Appl Microbiol Biotechnol 2016(Feb. 08)
Author:B. Guo, N. Sato, P. Biely, Y. Amano. K. Nozaki


Improvements in glucose sensitivity and stability of Trichoderma reesei β-glucosidase using site-directed mutagenesis
PLOS ONE 2016(Jan. 18)
Author:B. Guo, Y. Amano, K. Nozaki


Trichoderma reesei におけるセルラーゼ誘導・生産メカニズムの解明 ーβ-グルコシダーゼの役割についてー(総説)
応用糖質科学,6(2):96-102 2016
Author:野﨑功一,郭 博洋,畠中理志,天野良彦


Extra tyrosine in the carbohydrate-binding module of Irpex lacteus Xyn10B enhances its cellulose-binding ability
Biosci Biotechnol Biochem,79(5):738-746 2015(May 04)
Author:Nishijima, H; Nozaki, K; Mizuno, M; Arai, T; Amano, Y


Irpex lacteus由来GH10キシラナーゼの新規セルロース高吸着CBM1(総説)
応用糖質科学,4(2):154-159 2014(Apr. 01)
Author:西島拓人,野﨑功一,水野正浩,荒井勉,天野良彦


担子菌バイオマス分解系酵素群の機能解析(総説)
応用糖質科学,3(1):61-67 2013(Apr. 01)
Author:野﨑功一


Production of feruloylated arabino-oligosaccharides (FA-AOs) from beet fiber by hydrothermal treatment
J Supercritical Fluids,79:84-91 2013
Author:N. Sato, Y. Takano, M. Mizuno, K. Nozaki, S. Umemura, T. Matsuzawa, Y. Amano, S. Makishima


Regulation of adsorption behavior of carbohydrate-binding domain family 1 and endo-β-1,4-glucanase onto crystalline cellulose.
J Appl Glycosci,58(4):133-138 2011
Author:Nozaki, K; Nishijima, H; Arai, T; Mizuno, M; Sato, N; Amano, Y


Comparative study on the ability to produce gentiobiose in cellulose-producing bacteria Asaia bogorensis and Gluconacetobacter xylinus
J Appl Glycosci,58(4):147-150 2011
Author:Kumagai, A; Mizuno, M; Nozaki, K; Saxena, I M; Amano, Y


Ultrafine cellulose fibers produced by Asaia bogorensis, an acetic acid bacterium
Biomacromol,12(7):2815-2821 2011
Author:Kumagai, A; Mizuno, M; Kato, N; Nozaki, K; Togawa, E; Yamanaka, S; Okuda, K; Inder M. Saxena, Amano, Y


Enzymatic production of glucosylxylose using a cellobiose phosphorylase-yeast combined system
J Appl Glycosci,58:31-34 2011
Author:Kumagai, A; Tada, S; Nozaki, K; Mizuno, M; Kanda, T; Suzuki, S; Kusumoto, K; Sasaki, T; Kashiwagi, Y; Amano, Y


Improvement in the productivity of xylooligosaccharides from waste medium after mushroom cultivation by hydrothermal treatment with suitable pretreatment
Bioresour Technol,101(15):6006-6011 2010(Aug.)
Author:Sato, N; Shinji, K; Mizuno, M; Nozaki, K; Suzuki, M; Makishima, S; Shiroishi, M; Onoda, T; Takahashi, F; Kanda, T; Amano, Y


Screening and investigation of dye decolorization activity produced by basidiomycetes
J Biosci Bioeng 2008
Author:Nozaki, K; Beh, CH; Mizuno, M; Isobe, T; Shiroishi, M; Kanda, T; Amano, Y


Viability and cellulose synthesizing ability of Gluconacetobacter xylinus cells under high-hydrostatic pressure.
Extremophiles,11:693-698 2007
Author:Kato, N; Sato, T; Kato, C; Yajima, M; Sugiyama, J; Kanda, T; Mizuno, M; Nozaki, K; Yamanaka, S; Amano, Y


Structural analysis of the water-soluble carbohydrate from Asaia bogorensis by NMR spectroscopy
J Appl Glycosci,54:231-233 2007
Author:Kato, N; Mizuno, M; Nakai, Y; Nozaki, K; Suga, H; Kanda, T; Yamanaka, S; Amano, Y


Structure and characteristics of an endo-beta-1,4-glucanase, isolated from Trametes hirsuta, with high degradation to crystalline cellulose
Biosci Biotechnol Biochem,71(10):2375-2382 2007
Author:Nozaki, K; Seki, T; Matsui, K; Mizuno, M; Kanda, T; Amano, Y


Recovery of soluble sugars from waste medium for Enokitake (Flammulina velutipes) mushroom cultivation with hydrothermal reaction and enzyme digestion
J App Glycosci,53:261-266 2006
Author:Makishima, S; Nozaki, K; Mizuno, M; Netsu, E; Shinji, K; Shibayama, T; Kanda, T; Amano, Y


Accumulation of cello-oligosaccharides during bacterial cellulose production by Acetobacter xylinum
J Appl Glycosci,52:27-30 2005
Author:Ito, F; Amano, Y; Shiroishi, M; Nozaki, K; Saxena, IM; R Malcolm Brown Jr.; Kanda, T


Effects of culture medium components on cultivation of Flammulina velutipes and characteristics of fruit body
J Appl Glycosci,52:133-136 2005
Author:Shiroishi, M; Nishizawa, K; Nozaki, K; Amano, Y; Kanda, T


Mode of action of cellulases on dyed cotton with a reactive dye
Biosci Biotechnol Biochem,69(1):45-50 2005
Author:Yamada, M; Amano, Y; Horikawa, E; Nozaki, K; Kanda, T


Action of cellulase on partially modified cotton by carboxymethylation
Sen-i Gakkaishi,61(1):13-18 2005
Author:Yamada, M; Amano, Y; Horikawa, E; Izawa, Y; Nozaki, K; Kanda, T


Morphological observation of partially carboxymethylated cotton treated by cellulase
Sen-i Gakkaishi,61(2):48-54 2005
Author:Yamada, M; Amano, Y; Nozaki, K; Kanda, T


Hydrolysis of water-soluble and water-insoluble cellulosic substrates by endo-beta-1,4-glucanase from Acetobacter xylinum
J Appl Glycosci,51:297-301 2004
Author:Ito, F; Amano, Y; Nozaki, K; Saxena, IM; R. M. Brown Jr.; Kanda,T


Transglycosylation reaction and acceptor specificity of exo- and endo-type cellulases
J Appl Glycosci,51:87-92 2004
Author:Nozaki, K; Kano, A; Amano, Y; Murata, T; Usui, T; Ito, K; Kanda, T


The relationship between cellulase activity, oligosaccharides and cellulose production by Acetobacter xylinum ATCC23769
J Biol Macromol,4:83-90 2004
Author:Ito, F; Amano, Y; Nozaki, K; Saxena, IM;RM Brown Jr.; Kanda, T


Starch properties of the sago palm (Metroxylon sagu Rottb.) in different soils
Plant Foods Hum Nutr,59(3):85-92 2004
Author:Nozaki, K; Nuyim, T; Shinano, T; Hamada, S; Ito, H; Matsui, H; Osaki, M


Some characteristics of three groups in Flammulina velutipes classified by analysis of esterase isozymes
Mycosci,44:19-23 2003
Author:Nisizawa, K; Amano, Y; Nozaki, K; Hosokawa, N; Shiroishi, M; Kanda, T


Structure and physicochemical properties ofstarches from kidney bean seeds at immature, premature and mature stages of development
Carbohydr Res,338:463-469 2003
Author:Yoshida, H; Nozaki, K; Hanashiro, I; Yagi, F; Ito, H; Honma, M; Matsui, H; Takeda, Y


Molecular cloning of a cDNA encoding granule-bound starch synthase I from kidney bean seeds and expression in Esherichia coli
J Appl Glycosci,50:355-360 2003
Author:Isono, N; Ito, H; Senoura, T; Yoshikawa, H; Nozaki, K; Matsui, H


Aglycone specificity in transglycosylation of a xylanase produced from Basidiomycete, Hypsizigus marmoreus during the mushroom cultivation
J Appl Glycosci,49:137-143 2002
Author:Nishizawa,K; Amano, Y; Isobe, T; Nozaki, K; Shiroishi, M; Kanda, T


Differential characteristics and subcellular localization of two starch-branching enzyme isoforms encoded by a single gene in Phaseolus vulgaris L..
J Biol Chem,277:16538-16546 2002
Author:Hamada, S; Ito, H; Hiraga, S; Inagaki, K; Nozaki, K; Isono, N; Yoshimoto, Y; Takeda, Y; Matsui, H


Progress on studying the biological role of cellobiose dehydrogenase from Irpex lacteus
J Biol Macromol,2:11-18 2002
Author:Hai, PQ; Nozaki, K; Amano, Y; Kanda, T


Synergistic effects of cellobiose dehydrogenase, cellulases, and beta-glucosidase from Irpex lacteus in the degradation of various type of cellulose
J Appl Glycosci,49:9-17 2002
Author:Hai, PQ; Nozaki, K; Amano, Y; Kanda, T


Peroxidase assay in mycelia of Flammulina velutipes for screening undesirable changes inpinning
Mokuzai Gakkaishi,48(1):38-43 2002
Author:Nishizawa, K; Amano, Y; Shiroishi, M; Suzuki, I; Nozaki, K; Miyashita, K; Kanda, T


エノキタケ(Flammilina velutipes) 系統間遺伝的差異の解析
J Appl Glycosci,48:215-221 2001
Author:Nishizawa, K; Amano, Y; Nozaki, K; Shiroishi, M; Hosokawa, N; Miyashita, K; Kanda, T


Two starch branching enzyme isoforms occur in different fractions of developing seeds of kidney bean
Biochem J,359:23-34 2001
Author:Hamada, S; Nozaki, K; Ito, H; Yoshimoto, Y; Yoshida, H; Hiraga, S; Onodera, S; Honma, M; Takeda, Y; Matsui, H


Major isoforms of starch branching enzymes in premature seeds of kidney bean (Phaseolus vulgaris L.)
Biosci Biotechnol Biochem,65:1141-1148 2001
Author:Nozaki, K; Hamada, S; Nakamori, T; Ito, H; Sagisaka, S; Yoshida, H;Takeda, Y; Honma, M; Matsui, H


Heterogeneity of the morphology of growing starch granules at the developing seeds of kidney bean (Phaseolus vulgaris L.)
J Grad School Agr Hokkaido Univ,70(2):89-109 2001
Author:Nozaki, K; Isono, N; Hamada, S; Sagisaka, S; Hiraga, S; Ito, H; Matsui, H


Reactivities of cellulases from fungi towards ribbon-type bacterial cellulose and band-shaped bacterial cellulose
Cellulose,8(4):267-274 2001
Author:Amano, Y; Nozaki, K; Araki, T; Shibasaki, H; Kuga, S; Kanda, T


Purification and characterization of cellobiose dehydrodenase from Irpex lacteus and its adsorption on cellulose
J Appl Glycosci,47:311-318 2000
Author:Hai, PQ; Nozaki, K; Amano, Y; Kanda, T


Trafficking of starch synthase from the cytosol to functional sites in younger and older proplastidsin developing stolons of potato
J Plant Physiol,154:310-318 1999
Author:Sagisaka, S; Akita, T; Akase, T; Matsumoto, K; Nozaki, K; Matsui, H; Ito, H; Honma, M


Amylases and branching enzyme of developing kidney bean seeds on native electrophoretic gel
J Appl Glycosci,45:117-122 1998
Author:Nozaki, K; Matsui, H; Tonokawa, T; Mori, H; Ito, H; Honma, M; Chiba, S


Novel exopolygalacturonases produced by Alternaria mali
Biosci Biotechnol Biochem,61:75-80 1997
Author:Nozaki, K; Miyairi, K; Hozumi, S; Fukui, Y; Okuno, T


MISC
革新的環境技術の創製ー糸状菌バイオマス分解酵素の生産能力の増強技術
ケミカルエンジニヤリング(化学工業社) 2018
Author:野﨑功一


セルロース分解を補助する謎のタンパク質
生物工学会誌,93(11):695 2015
Author:野﨑功一


セルラーゼの酵素反応を促進する新規タンパク質(スオレニン)の機能解析
技報こまくさ,11:6-9 2013(Nov. 01)
Author:野﨑功一


リグニンを分解する第3のペルオキシダーゼ
化学と生物,40:180-181 2002
Author:Nozaki, K


Insight in the biological role of cellobiose dehydrogenase
J Biol Macromol,1:37-43 2001
Author:Hai, PQ; Amano, Y; Nozaki, K; Kanda, T


Branching enzyme
Glycoforum解説 2000
Author:Nozaki, K; Hamada, S

共同研究等希望テーマ
バイオマスの酵素分解
セルラーゼ誘導・生産
バイオレメディエーション
糖質の構造解析
研究費
科学研究費補助金(研究代表者)
2017 - 2019 , 基盤研究 (C)
2013 - 2015 , 基盤研究 (C)

その他
2015 - 2017, NEDO再委託事業
2013 - 2018, 物質・デバイス領域共同研究拠点・基盤共同研究
2012, 信州大学工学部若里会研究助成金
2006, クリタ水・環境科学振興財団研究助成金
2001, ホクト生物科学振興財団研究助成金
研究諸活動
在外研究員等
2007-2008 , ウィーン工科大学 化学工学研究所

教育活動実績

授業等
前期 , 遺伝子工学
前期 , 生物化学実験(分担)
前期 , 食品バイテク講義・同実習(修士,分担)
前期 , 酵素機能学特論(博士)
後期 , 生物化学・同演習(分担)
後期 , 応用生物学特論(修士)
後期 , 食品バイオテクノロジー(修士)
通年 , バイオ・プロセス工学特別実験1(修士)