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川茂幸  カワ シゲユキ

教員組織電話番号
教育組織総合健康安全センターFAX番号
職名特任教授メールアドレス
住所390-8621 松本市旭3-1-1ホームページURL

更新日:2018/07/12

プロフィール

研究分野
膵臓病学
消化器腫瘍学
現在の研究課題
自己免疫性膵炎の臨床的・基礎的検討

ビタミンDアナログ・ビタミンAアナログ・PPARγリガンドによる膵癌の分化誘導療法

膵癌の腫瘍マーカー

所属学会
所属学会
日本内科学会
日本消化器病学会
日本膵臓学会
日本内視鏡学会
日本癌学会
日本糖尿病学会
学歴
出身学校・専攻等(大学院を除く)
1977 , 信州大学 , 医学部

取得学位
医学博士
研究職歴等
研究職歴
2017- , 信州大学総合健康安全センター 特任教授
2005- , 信州大学健康安全センター 教授
1998- , 信州大学(医学部) 助教授
1993- , 信州大学(医学部) 講師
1985- , 信州大学(医学部) 助手
1977- , 信州大学医学部第二内科 医員

研究活動業績

研究業績(著書・
発表論文等)
著書
What is the evidence measuring immune markers.
Willey Blackwell , The Pancreas , :544-549 2018
Author:Shigeyuki Kawa


Other Urological Lesions (Testis, Paratestis Lesions, Bladder, Prostate etc.)
IgG4-Related Kidney Disease , :173-185 2016
Author:Takeshi Uehara, Yasunari Fujinaga, Teruyuki Ogawa, Shigeyuki Kawa


IgG4-Related Disease: History and overvies
IgG4-Related Kidney Disease , :3-24 2016
Author:Shigeyuki Kawa


Serology.
Springer Korea , Autoimmune pancreatitis , :61-68 2016
Author:Shigeyuki Kawa, Takayuki Watanabe, Takashi Muraki


自己免疫性膵炎の長期予後
中外医学社 , Annual Review 2015消化器 , :169-175 2015
Author:川 茂幸, 丸山 真弘, 渡邉 貴之, 伊藤 哲也, 新倉 則和


発見の経緯
診断と治療社 , 最新IgG4関連疾患 , :13-18 2015
Author:川 茂幸


自己免疫性膵炎-予後—特に慢性膵炎への移行について
診断と治療社 , 最新IgG4関連疾患 , :92-95 2015
Author:新倉則和、川 茂幸


自己免疫性膵炎-病因②-免疫遺伝学的背景
診断と治療社 , 最新IgG4関連疾患 , :96-101 2015
Author:太田正穂、川 茂幸


Developmen to chronic pancreatitis.
Springer Korea , Autoimmune pancreatitis , :165-174 2015
Author:Masahiro Maruyama, Norikazu Arakura, Shigeyuki Kawa.


Prognosis and Long Term Outcomes of Autoimmune Pancreatitis
Exocrine Pancreas Knowledge Base , The Pancreapedia , :on line 2013
Author:Kawa, Shigeyuki. Maruyama, Masahiro. Watanabe, Takayuki


Pharmacotherapy of IgG4-related disease.
Springer Japan , IgG4-related Disease , :45-50 2013
Author:Kawano M. Yamada K, Kawa S


History: pancreas.
Springer Japan , IgG4-related Disease , :13-17 2013
Author:Kawa S, Watanabe T, Ito T, Maruyama M, Ozaki Y, Muraki T, Hamano H, Arakura N.


An overview
Springer Japan , IgG4-related Disease , :3-7 2013
Author:Kawa S, Kawano M


Autoimmune pancreatitis and IgG4-related disease
Academic Press , The Autoimmune Diseases , 5th ed:935-949 2013
Author:Kawa S, Hamano H, Kiyosawa K.



前田書店 , IgG4関連疾患アトラス 2012
Author:川茂幸、川野充弘 編集


IgG4関連疾患アトラス、歴史:膵臓
前田書店 2012
Author:川 茂幸、渡邊貴之、丸山真弘、伊藤哲也、丸山雅史、尾崎弥生、村木 崇、浜野英明、新倉則和



前田書店 , IgG4関連疾患への誘い 2010
Author:川茂幸、川野充弘 編集



診断と治療社 , 自己免疫性膵炎—病態から診断・治療まで 2009
Author:岡崎和一、川茂幸、神澤輝実 編集


Pancreatitis
Academic Press , The autoimmune diseases , :779-86 2006
Author:Kawa S, Hamano H, Kiyosawa K


論文
Factors in glucocorticoid regimens associated with treatment response and relapses of IgG4-related disease: a multicentre study.
Sci Rep. 2018
Author:Shirakashi M, Yoshifuji H, Kodama Y, Chiba T, Yamamoto M, Takahashi H, Uchida K, Okazaki K, Ito T, Kawa S, Yamada K, Kawano M, Hirata S, Tanaka Y, Moriyama M, Nakamura S, Kamisawa T, Matsui S, Tsuboi H, Sumida T, Shibata M, Goto H, Sato Y, Yoshino T, Mimori T.


Promoter hypomethylation of SKI in autoimmune pancreatitis
Pathol Res Pract.,214(4):492-497 2018
Author:Kinugawa Y, Uehara T, Matsuda K, Kobayashi Y, Nakajima T, Hamano H, Kawa S, Higuchi K, Hosaka N, Shiozawa S, Ishigame H, Nakamura T, Maruyama Y, Nakazawa K, Nakaguro M, Sano K, Ota H.


High vaccination coverage is associated with low epidemic level of seasonal influenza in elementary schools: an observational study in Matsumoto City, Japan.
BMC Infect Dis. 2018
Author:Uchida M, Kaneko M, Hidaka Y, Yamamoto H, Honda T, Takeuchi S, Saito M, Kawa S.


An International, Multi-Specialty Validation Study of the IgG4-Related Disease Responder Index.
Arthritis Care Re 2018
Author:Wallace ZS, Khosroshahi A, Carruthers MD, Perugino CA, Choi H, Campochiaro C, Culver EL, Cortazar F, Della-Torre E, Ebbo M, Fernandes A, Frulloni L, Hart P, Karadag O, Kawa S, Kawano M, Kim MH, Lanzillotta M, Matsui S, Okazaki K, Ryu JH, Saeki T, Schleinitz N, Tanasa P, Umehara H, Webster G, Zhang W, Stone JH.


Clinical course of type 1 autoimmune pancreatitis patients without steroid treatment: a Japanese multicenter study of 97 patients.
J Hepatobiliary Pancreat Sci.,25(4):223-230 2018
Author:Kubota K, Kamisawa T, Hirano K, Hirooka Y, Uchida K, Ikeura T, Shiomi H, Ohara H, Shimizu K, Arakura N, Kanno A, Sakagami J, Itoi T, Ito T, Ueki T, Nishino T, Inui K, Mizuno N, Yoshida H, Sugiyama M, Iwasaki E, Irisawa A, Okazaki K, Kawa S, Shimosegawa T, Takeyama Y, Chiba T.


IgG4-related Disease - A Systemic Disease that Deserves Attention Regardless of One's Subspecialty.
Intern Med 2017
Author:Hamano H, Tanaka E, Ishizaka N, Kawa S.


New clues to the nature of immunoglobulin G4-related disease: a retrospective Japanese multicenter study of baseline clinical features of 334 cases.
Arthritis Res Ther,20:262 2017
Author:Yamada K, Yamamoto M, Saeki T, Mizushima I, Matsui S, Fujisawa Y, Hara S, Takahashi H, Nomura H, Kawa S, Kawano M.


Clinical features of IgG4-related periaortitis/periarteritis based on the analysis of 179 patients with IgG4-related disease: a case-control study.
Arthritis Res Ther,19:223 2017
Author:Ozawa M, Fujinaga Y, Asano J, Nakamura A, Watanabe T, Ito T, Muraki T, Hamano H, Kawa S.


.Serum IgG4 Concentration in IgG4-Related Disease.
Clin Lab,63(9):1323-1337 2017
Author:Kawa S, Skold M, Ramsden DB, Parker A, Harding SJ


Association of autoimmune hepatitis with Src homology 2 adaptor protein 3 gene polymorphisms in Japanese patients.
J Hum Genet,Jul 13. doi: 10.1038/jhg.2017.74. 2017
Author:Umemura T, Joshita S, Hamano H, Yoshizawa K, Kawa S, Tanaka E, Ota M


Usefulness of three-dimensional magnetic resonance cholangiopancreatography with partial maximum intensity projection for diagnosing autoimmune pancreatitis.
Pancreatology,17(4):567-571 2017
Author:Yanagisawa S, Fujinaga Y, Watanabe T, Maruyama M, Muraki T, Takahashi M, Fujita A, Fujita S, Kurozumi M, Ueda K, Hamano H, Kawa S, Kadoya M.


Methylation of Tumor Suppressor Genes in Autoimmune Pancreatitis.
Pancreas,46(5):614-618 2017
Author:Kinugawa Y, Uehara T, Sano K, Matsuda K, Maruyama Y, Kobayashi Y, Nakajima T, Hamano H, Kawa S, Higuchi K, Hosaka N, Shiozawa S, Ishigame H, Ota H.


Low-dose maintenance steroid treatment could reduce the relapse rate in patients with type 1 autoimmune pancreatitis: a long-term Japanese multicenter analysis of 510 patients
J Gastroenterol,52(8):955-964 2017
Author:Kubota K, Kamisawa T, Okazaki K, Kawa S, Hirano K, Hirooka Y, Uchida K, Shiomi H, Ohara H, Shimizu K, Arakura N, Kanno A, Sakagami J, Itoi T, Ito T, Ueki T, Nishino T, Inui K, Mizuno N, Yoshida H, Sugiyama M, Iwasaki E, Irisawa A, Shimosegawa T, Takeyama Y, Chiba T.


International consensus for the treatment of autoimmune pancreatitis
Pancreatology.,17(1):1-6 2017
Author:Okazaki K, Chari ST, Frulloni L, Lerch MM, Kamisawa T, Kawa S, Kim MH, Lévy P, Masamune A, Webster G, Shimosegawa T.


Effectiveness of vaccination and wearing masks on seasonal influenza in Matsumoto City, Japan, in the 2014/2015 season: An observational study among all elementary schoolchildren.
Prev Med Rep.,5:86-91 2017
Author:Uchida M, Kaneko M, Hidaka Y, Yamamoto H, Honda T, Takeuchi S, Saito M, Kawa S


Immunogenetics of IgG4-Related AIP
Curr Top Microbiol Immunol,401:35-44 2017
Author:Ota M, Umemura T, Kawa S


The Immunobiology of Immunoglobulin G4 and Complement Activation Pathways in IgG4-Related Disease
Curr Top Microbiol Immunol.,401:61-73 2017
Author:Kawa S


Randomised controlled trial of long-term maintenance corticosteroid therapy in patients with autoimmune pancreatitis
Gut,66(3):487-494 2017
Author:Masamune A, Nishimori I, Kikuta K, Tsuji I, Mizuno N, Iiyama T, Kanno A, Tachibana Y, Ito T, Kamisawa T, Uchida K, Hamano H, Yasuda H, Sakagami J, Mitoro A, Taguchi M, Kihara Y, Sugimoto H, Hirooka Y, Yamamoto S, Inui K, Inatomi O, Andoh A, Nakahara K, Miyakawa H, Hamada S, Kawa S, Okazaki K, Shimosegawa T


Prospective Epidemiological Evaluation of Seasonal Influenza in All Elementary Schoolchildren in Matsumoto City, Japan, in 2014/2015
Jpn J Infect Dis,70(3):333-339 2016
Author:Uchida M, Kaneko M, Hidaka Y, Yamamoto H, Honda T, Takeuchi S, Saito M, Kawa S


Current Concepts and Diagnosis of IgG4-Related Pancreatitis (Type 1 AIP).
Semin Liver Dis,36(3):257-73 2016
Author:Kawa S


Autoimmune Pancreatitis Can Transform Into Chronic Features Similar to Advanced Chronic Pancreatitis With Functional Insufficiency Following Severe Calcification.
Pancreas,45(8):1189-95 2016
Author:Kanai K, Maruyama M, Kameko F, Kawasaki K, Asano J, Oguchi T, Watanabe T, Ito T, Muraki T, Hamano H, Matsumoto A, Arakura N, Kawa S.


Evidence-based clinical practice guidelines for chronic pancreatitis 2015
J Gastroenterol,51(2):85-92 2015
Author:Ito T, Ishiguro H, Ohara H, Kamisawa T, Sakagami J, Sata N, Takeyama Y, Hirota M, Miyakawa H, Igarashi H, Lee L, Fujiyama T, Hijioka M, Ueda K, Tachibana Y, Sogame Y, Yasuda H, Kato R, Kataoka K, Shiratori K, Sugiyama M, Okazaki K, Kawa S, Tando Y, Kinoshita Y, Watanabe M, Shimosegawa T.


Association Between Immunoglobulin G4-related Disease and Malignancy within 12 Years after Diagnosis: An Analysis after Longterm Followup.
J Rheumatol.,42(11):2135-42 2015
Author:Asano J, Watanabe T, Oguchi T, Kanai K, Maruyama M, Ito T, Muraki T, Hamano H, Arakura N, Matsumoto A, Kawa S.


Clinicopathological Features of Type 2 Autoimmune Pancreatitis in Japan: Results of a Multicenter Survey.
Pancreas,44(7):1072-7 2015
Author:Notohara K, Nishimori I, Mizuno N, Okazaki K, Ito T, Kawa S, Egawa S, Kihara Y, Kanno A, Masamune A, Shimosegawa T.


Investigation of susceptibility genes triggering lachrymal/salivary gland lesion complications in Japanese patients with type 1 autoimmune pancreatitis.
PLoS One,:May 18;10(5):e0127078. 2015
Author:Oguchi T, Ota M, Ito T, Hamano H, Arakura N, Katsuyama Y, Meguro A, Kawa S.


Extracorporeal shock wave lithotripsy treatment of pancreatic stones complicated with advanced stage autoimmune pancreatitis.
BMC Gastroenterol,:Mar 10;15(1):28 2015
Author:Maruyama M, Watanabe T, Kanai K, Oguchi T, Asano J, Ito T, Muraki T, Hamano H, Arakura N, Uehara T, Kawa S.


Nationwide epidemiological survey of autoimmune pancreatitis in Japan in 2011.
Pancreas,44(4):535-9 2015
Author:Kanno A, Masamune A, Okazaki K, Kamisawa T, Kawa S, Nishimori I, Tsuji I, Shimosegawa T.


International consensus guidance statement on the management and treatment of IgG4-related disease.
Arthritis Rheumatol,:Mar 25 2015
Author:Khosroshahi A, Wallace ZS, Crowe JL, Akamizu T, Azumi A, Carruthers M, Chari S, Della-Torre E, Frulloni L, Goto H, Hart P, Kamisawa T, Kawa S, Kawano M, Kim MH, Kodama Y, Kubota K, Lerch MM, Löhr M, Masaki Y, Matsui S, Mimori T, Nakamura S, Nakazawa T, Ohara H, Okazaki K, Ryu JH, Saeki T, Schleinitz N, Shimatsu A, Shimosegawa T, Takahira M, Takahashi H, Tanaka A, Topazian M, Umehara H, Webster G, Witzig T, Yamamoto M, Zhang W, Chiba T, Stone JH.


Autoimmune pancreatitis complicated with inflammatory bowel disease and comparative study of type 1 and type 2 autoimmune pancreatitis.
,50(7):805-15 2015
Author:Kawa S, Okazaki K, Notohara K, Watanabe M, Shimosegawa T; Study Group for Pancreatitis Complicated with Inflammatory Bowel Disease organized by The Research Committee for Intractable Pancreatic Disease (Chairman: Tooru Shimosegawa) and The Research Committee for Intractable Inflammatory Bowel Disease (Chairman: Mamoru Watanabe), both of which are supported by the Ministry of Health, Labour, and Welfare of Japan.


Reply to Intrapancreatic Biliary Stricture in Autoimmune Pancreatitis Should Not Be Included in IgG4-Related Sclerosing Cholangitis.
Pancreas,43(7):1123 2014
Author:Watanabe T, Muraki T, Arakura N, Kawa S.


Autoimmune pancreatitis can develop into chronic pancreatitis.
Orphanet J Rare Dis.,2014 May 21;9(1):77 2014
Author:Maruyama M, Watanabe T, Kanai K, Oguchi T, Asano J, Ito T, Ozaki Y, Muraki T, Hamano H, Arakura N, Kawa S.


Hepatic Infarction Complicated with Acute Pancreatitis Precisely Diagnosed with Gadoxetate Disodium-enhanced Magnetic Resonance Imaging.
Intern Med.,53(19):2215-21 2014
Author:Maruyama M, Yamada A, Kuraishi Y, Shibata S, Fukuzawa S, Yamada S, Arakura N, Tanaka E, Kadoya M, Kawa S.


Evaluation of the spread of pandemic influenza A/H1N1 2009 among Japanese university students
Environmental Health and Preventive Medicine,Oct;43(7):1123. 2014
Author:Uchida, M; Kaneko, M; Tsukahara, T; Washizuka, S; Kawa, S


Mechanisms of Lower Bile Duct Stricture in Autoimmune Pancreatitis
Pancreas,43(2):255-260 2014
Author:Watanabe, T; Maruyama, M; Ito, T; Maruyama, M; Muraki, T; Hamano, H; Arakura, N; Hasebe, O; Kawa, S


Inflammation of colon adenoma in the setting of type 1 autoimmune pancreatitis.
Pathol Int,64(2):67-74 2014
Author:Uehara T, Hamano H, Suga T, Kawa S, Yoshizawa A, Kobayashi Y, Murata K, Oki K, Sano K, Onodera R, Ota H.


Comparison of histopathological features of pancreatic carcinoma and type 1 autoimmune pancreatitis.
Pathol Int.,64(2):51-7 2014
Author:Uehara T, Hamano H, Kawa S, Kobayashi Y, Yoshizawa A, Oki K, Nakata R, Kobayashi A, Sano K, Ota H.


Amendment of the Japanese Consensus Guidelines for Autoimmune Pancreatitis, 2013 III. Treatment and prognosis of autoimmune pancreatitis.
J Gastroenterol.,49(6) 2014
Author:Kamisawa T, Okazaki K, Kawa S, Ito T, Inui K, Irie H, Nishino T, Notohara K, Nishimori I, Tanaka S, Nishiyama T, Suda K, Shiratori K, Tanaka M, Shimosegawa T; The Working Committee of the Japan Pancreas Society and the Research Committee for Intractable Pancreatic Disease supported by the Ministry of Health, Labour and Welfare of Japan.


Amendment of the Japanese Consensus Guidelines for Autoimmune Pancreatitis, 2013 II. Extrapancreatic lesions, differential diagnosis.
J Gastroenterol.,49(5):765-84 2014
Author:Kawa S, Okazaki K, Kamisawa T, Kubo K, Ohara H, Hasebe O, Fujinaga Y, Irisawa A, Notohara K, Ito T, Inui K, Irie H, Nishino T, Nishimori I, Tanaka S, Nishiyama T, Suda K, Shiratori K, Tanaka M, Shimosegawa T; The Working Committee of the Japan Pancreas Society and the Research Committee for Intractable Pancreatic Disease supported by the Ministry of Health, Labour and Welfare of Japan.


Amendmentof the Japanese Consensus Guidelines for Autoimmune Pancreatitis, 2013 I. Concept and diagnosis of autoimmune pancreatitis.
J Gastroenterol,49(4):567-88 2014
Author:Okazaki K, Kawa S, Kamisawa T, Ito T, Inui K, Irie H, Nishino T, Notohara K, Nishimori I, Tanaka S, Nishiyama T, Suda K, Shiratori K, Tanaka M, Shimosegawa T; The Working Committee of the Japan Pancreas Society and the Research Committee for Intractable Pancreatic Disease supported by the Ministry of Health, Labour and Welfare of Japan.


Occurrence of IgG4-related hypophysitis lacking IgG4 bearing plasma cell infiltration during steroid therapy.
Intern Med,53(7):753-7 2014
Author:Ohkubo Y, Sekido T, Takeshige T, Ishi H, Takei M, Nishio S, Yamazaki M, Komatsu M., Kawa S, Suzuki S.


Effects of personality on overtime work: a cross-sectional pilot study among Japanese white-collar workers
BMC RESEARCH NOTES,7(1):180 2014
Author:Uchida, M; Kaneko, M; Kawa, S


Comparison of carbon dioxide and air insufflation use by non-expert endoscopists during endoscopic retrograde cholangiopancreatography.
Dig Endosc,25(2):189-96 2013
Author:Muraki T, Arakura N, Kodama R, Yoneda S, Maruyama M, Itou T, Watanabe T, Maruyama M, Matsumoto A, Kawa S


International Consensus Diagnostic Criteria for Autoimmune Pancreatitis and its Japanese Amendment Have Improved Diagnostic Ability over Existing Criteria
Gastroenterol Res Pract,:456965 2013
Author:Masahiro Maruyama, Takayuki Watanabe, Keita Kanai, Takaya Oguchi, Takashi Muraki, Hideaki Hamano, Norikazu Arakura, and Shigeyuki Kawa


Effects of School Closure during Influenza A/H1N1 Pandemic in 2009 in Japan
Nihon Eiseigaku Zasshi,68(2):103-17 2013
Author:Uchida M, Kaneko M, Yamamoto H, Honda T, Kawa S.


IgG4-related disease-like fibrosis as an indicator of IgG4-related lymphadenopathy.
Ann Diagn Pathol,on line:on line 2013
Author:Uehara T, Masumoto J, Yoshizawa A, Kobayashi Y, Hamano H, Kawa S, Oki K, Oikawa N, Honda T, Ota H.


Type 1 Autoimmune Pancreatitis Can Transform into Chronic Pancreatitis: A Long-Term Follow-Up Study of 73 Japanese Patients.
Int J Rheumatol.,on line:on line 2013
Author:Masahiro Maruyama, Norikazu Arakura, Yayoi Ozaki, Takayuki Watanabe, Tetsuya Ito, Suguru Yoneda, Masafumi Maruyama, Takashi Muraki, Hideaki Hamano, Akihiro Matsumoto, and Shigeyuki Kawa.


Establishment of a Serum IgG4 Cut-off Value for the Differential Diagnosis of IgG4-related Sclerosing Cholangitis- A Japanese Cohort.
J Gastroenterol Hepatol,28(7):1247-51 2013
Author:Ohara H, Nakazawa T, Kawa S, Kamisawa T, Shimosegawa T, Uchida K, Hirano K, Nishino T, Hamano H, Kanno A, Notohara K, Hasebe O, Muraki T, Ishida E, Naitoh I, Okazaki K.


Two siblings with type 1 autoimmune pancreatitis.
Int Med,52(8):895-899 2013
Author:Watanabe T, Maruyama M, Ito T, Kanai K, Oguchi T, Muraki T, Hamano H, Arakura N, Ota M, Kawa s.


Clinical Features of a New Disease Concept, IgG4-related Thyroiditis. Scand J Rheumatol.
Scand J Rheumatol.,42(4):325-30 2013
Author:Watanabe T, Maruyama M, Ito T, Fujinaga Y, Ozaki Y, Maruyama M, Kodama R, Muraki T, Hamano H, Arakura N, Kadoya M, Suzuki S, Komatsu M, Shimojo H, Notohara K, Uchida M, Kawa S.


Evaluation of factors affecting variations in influenza A/H1N1 history in university students, Japan
JOURNAL OF INFECTION AND CHEMOTHERAPY,19(4):665-672 2013
Author:Uchida, Mitsuo; Tsukahara, Teruomi; Kaneko, Minoru; Washizuka, Shinsuke; Kawa, Shigeyuki


Does change of residence affect pollinosis? A study of Japanese university students
INTERNATIONAL JOURNAL OF ENVIRONMENTAL HEALTH RESEARCH 2013
Author:Uchida, Mitsuo ; Kaneko, Minoru; Kawa, Shigeyuki


Long-term outcomes of autoimmune pancreatitis: a multicentre, international analysis.
Gut,Epub ahead of print 2012
Author:Hart PA, Kamisawa T, Brugge WR, Chung JB, Culver EL, Czakó L, Frulloni L, Go VL, Gress TM, Kim MH, Kawa S, Lee KT, Lerch MM, Liao WC, Löhr M, Okazaki K, Ryu JK, Schleinitz N, Shimizu K, Shimosegawa T, Soetikno R, Webster G, Yadav D, Zen Y, Chari ST.


A Case of Mikulicz's Disease Complicated by Malignant Lymphoma: A Postmortem Histopathological Finding.
Intern Med,51(4):419-23 2012
Author:Uehara T, Ikeda S, Hamano H, Kawa S, Moteki H, Matsuda K, Kaneko Y, Hara E.


Effect of short-term school closures on the H1N1 pandemic in Japan: a comparative case study.
Infection,40(5):549-556 2012
Author:Uchida M, Tsukahara T, Kaneko M, Washizuka S, Kawa S.


Consensus statement on the pathology of IgG4-related disease
Mod Pathol,25(9):1181-92 2012
Author:Deshpande V, Zen Y, Chan JK, Yi EE, Sato Y, Yoshino T, Klöppel G, Heathcote JG, Khosroshahi A, Ferry JA, Aalberse RC, Bloch DB, Brugge WR, Bateman AC, Carruthers MN, Chari ST, Cheuk W, Cornell LD, Fernandez-Del Castillo C, Forcione DG, Hamilos DL, Kamisawa T, Kasashima S, Kawa S, Kawano M, Lauwers GY, Masaki Y, Nakanuma Y, Notohara K, Okazaki K, Ryu JK, Saeki T, Sahani DV, Smyrk TC, Stone JR, Takahira M, Webster GJ, Yamamoto M, Zamboni G, Umehara H, Stone JH.


IgG4-Related disease: recommendations for the nomenclature of this condition and its individual organ system manifestations.
Arthritis Rheum,:on line 2012
Author:Stone JH, Khosroshahi A, Deshpande V, Chan JK, Heathcote JG, Aalberse R, Azumi A, Bloch DB, Brugge WR, Carruthers MN, Cheuk W, Cornell L, Castillo CF, Ferry JA, Forcione D, Klöppel G, Hamilos DL, Kamisawa T, Kasashima S, Kawa S, Kawano M, Masaki Y, Notohara K, Okazaki K, Ryu JK, Saeki T, Sahani D, Sato Y, Smyrk T, Stone JR, Takahira M, Umehara H, Webster G, Yamamoto M, Yi E, Yoshino T, Zamboni G, Zen Y, Chari S.


Clinical diagnostic criteria of IgG4-related sclerosing cholangitis 2012.
J Hepatobiliary Pancreat Sci,19(5):536-42 2012
Author:Ohara H, Okazaki K, Tsubouchi H, Inui K, Kawa S, Kamisawa T, Tazuma S, Uchida K, Hirano K, Yoshida H, Nishino T, Ko SB, Mizuno N, Hamano H, Kanno A, Notohara K, Hasebe O, Nakazawa T, Nakanuma Y, Takikawa H.


The Utility of Serum IgG4 Concentrations as a Biomarker
International Journal of Rheumatology,on line:on line 2012
Author:Kawa S, Ito T, Watanabe T, Maruyama M, Hamano H, Maruyama M, Muraki T, Arakura N


Comprehensive diagnostic criteria for IgG4-related disease (IgG4-RD)
Mod Rheumatol,22:21-30 2012
Author:Umehara H, Okazaki K, Masaki Y, Kawano M, Yamamoto M, Saeki T, Matsui S, Yoshino T, Nakamura S, Kawa S, Hamano H, Kamisawa T, Shimosegawa T, Shimatsu A, Nakamura S, Ito T, Notohara K, Sumida T, Tanaka Y, Mimori T, Chiba T, Mishima M, Hibi T, Tsubouchi H, Inui K, Ohara H


Characteristic magnetic resonance features of focal autoimmune pancreatitis useful for differentiation from pancreatic cancer
Jpn J Radiol,on line:on line 2012
Author:Sugiyama Y, Fujinaga Y, Kadoya M, Ueda K, Kurozumi M, Hamano H, Kawa S


Type 1 autoimmune pancreatitis
Orphanet Journal of Rare Diseases,on line:on line 2012
Author:Zen Y, Bogdanos DP, Kawa S


Risk factors for pancreatic stone formation in autoimmune pancreatitis over a long-term course.
J Gastroenterol,47(5):553-560 2012
Author:Maruyama M, Arakura N, Ozaki Y, Watanabe T, Ito T, Yoneda S, Maruyama M, Muraki T, Hamano H, Matsumoto A, Kawa S


IgG4-related airway involvement which developed in a patient receiving corticosteroid therapy for autoimmune pancreatitis
Intern Med,50(24):2023-2026 2011
Author:Yamamoto H, Yasuo M, Nomura Y, Agatsuma T, Ushiki A, Yokoyama T, Urushihata K, Hanaoka M, Koizumi T, Iwaya M, Yoshizawa A, Kawakami S, Hamano H, Kawa S, Kubo K


Polymorphism in the KCNA3 gene is associated with susceptibility to autoimmune pancreatitis in the Japanese population
Dis Markers,31(4):223-229 2011
Author:Ota M, Ito T, Umemura T, Katsuyama Y, Yoshizawa K, Hamano H, Kawa S


A novel clinical entity, IgG4-related disease (IgG4RD): general concept and details.
Mod Rheumatol,on line:on line 2011
Author:Umehara H, Okazaki K, Masaki Y, Kawano M, Yamamoto M, Saeki T, Matsui S, Sumida T, Mimori T, Tanaka Y, Tsubota K, Yoshino T, Kawa S, Suzuki R, Takegami T, Tomosugi N, Kurose N, Ishigaki Y, Azumi A, Kojima M, Nakamura S, Inoue D; The Research Program for Intractable Disease by Ministry of Health, Labor and Welfare (MHLW) Japan G4 team.


How the H1N1 influenza epidemic spread among university students in Japan: Experience from Shinshu University
Am J Infect Control,40(3):on line 2011
Author:Uchida M, Tsukahara T, Kaneko M, Washizuka S, Kawa S


Elevated IgG4 levels in patients demonstrating sarcoidosis-like radiologic findings.
Medicine (Baltimore),90:194-200 2011
Author:107. Tsushima K, Yokoyama T, Kawa S, Hamano H, Tanabe T, Koizumi T, Honda T, Kawakami S, Kubo K.


IgG4-Related Pleural Disease Diagnosed by a Re-Evaluation of Chronic Bilateral Pleuritis in a PatientWho Experienced Occasional Acute Left Bacterial Pleuritis.
Intern Med,50(8):893-897 2011
Author:Yamamoto H, Suzuki T, Yasuo M, Kobayashi O, Tsushima K, Ito M, Urushihata K, Yamazaki Y, Hanaoka M, Koizumi T, Uehara T, Kawakami S, Hamano H, Kawa S, Kubo K.


Infraorbital nerve swelling associated with autoimmune pancreatitis.
Jpn J Radiol,29(3):194-201 2011
Author:Watanabe T, Fujinaga Y, Kawakami S, Hatta T, Hamano H, Kawa S, Kadoya M.


Radiologic Findings of IgG4-Related Disease
Current Immunology Reviews,7(2):186-203 2011
Author:Fujinaga Y, Kadoya M, Hamano H, Kawa S, Momose M, Kawakami S, Watanabe T, Sugiyama Y , Uehara T.


Autoimmune Pancreatitis and Diagnostic Criteria
Current Immunology Reviews,7(2):144-161 2011
Author:Kawa S, Fujinaga Y, Ota M, Hamano H, Bahram S


History of Autoimmune Pancreatitis and Mikulicz’s Disease
Current Immunology Reviews,7(2):137-143 2011
Author:Kawa S, Sugai S


International Consensus Diagnostic Criteria for Autoimmune Pancreatitis: Guidelines of the International Association of Pancreatology.
Pancreas,40(3):352-358 2011
Author:Shimosegawa T, Chari ST, Frulloni L, Kamisawa T, Kawa S, Mino-Kenudson M, Kim MH, Klöppel G, Lerch MM, Löhr M, Notohara K, Okazaki K, Schneider A, Zhang L.


Swine-Origin Influenza A Outbreak 2009 at Shinshu University, Japan.
BMC Public Health,4(11):79 2011
Author:Uchida M, Tsukahara T, Kanako M, Washizuka S, Kawa S


Clinical significance of immunoglobulin G4-associated autoimmune hepatitis.
J Gastroenterol,46:48-55 2011
Author:Umemura T, Zen Y, Hamano H, Joshita S, Ichijo T, Yoshizawa K, Kiyosawa K, Ota M, Kawa S, Nakanuma Y, Tanaka E


Semiquantitative measurement of pulmonary hilar gallium-67 uptake using single photon emission computed tomography/computed tomography for the diagnosis of autoimmune pancreatitis.
Jpn J Radiol.,28(10):733-9 2010
Author:Momose M, Kadoya M, Yano K, Miyasaka T, Fujinaga Y, Matsushita T, Yanagisawa S, Hamano H,Kawa S.


Chronic gastritis in the setting of autoimmune pancreatitis.
Am J Surg Pathol.,34(9):1241-9 2010
Author:Uehara T, Hamano H, Kawa S, Sano K, Oki K, Kobayashi Y, Nagaya T, Akamatsu T, Kurozumi M, Fujinaga Y, Tanaka E, Honda T, Ota H


Japanese consensus guidelines for management of autoimmune pancreatitis: III. Treatment and prognosis of AIP.
J Gastroenterol,45(5):471-477 2010
Author:Kamisawa T, Okazaki K, Kawa S, Shimosegawa T, Tanaka M; Research Committee for IntractablePancreatic Disease and Japan Pancreas Society.


Japanese consensus guidelines for management of autoimmune pancreatitis: II. Extrapancreatic lesions, differential diagnosis.
J Gastroenterol,45(4):355-369 2010
Author:Kawa S, Okazaki K, Kamisawa T, Shimosegawa T, Tanaka M; Working members of Research Committee for Intractable Pancreatic Disease and Japan Pancreas Society.


Japanese consensus guidelines for management of autoimmune pancreatitis: I. Concept and diagnosis of autoimmune pancreatitis.
J Gastroenterol,45(3):249-265 2010
Author:Okazaki K, Kawa S, Kamisawa T, Shimosegawa T, Tanaka M; Research Committee for Intractable Pancreatic Disease and JapanPancreas Society.


A Novel heterophilic antibody interaction involves IgG4
Scand J Immunol,71(2):109-114 2010
Author:Ito T, Kitahara K, Umemura T, Ota M, Shimozuru Y, Kawa S, Bahram S.


Characteristic findings in images of extra-pancreatic lesions associated with autoimmune pancreatitis.
Eur J Radiol,76(2):228-238 2010
Author:Fujinaga Y, Kadoya M, Kawa S, Hamano H, Ueda K, Momose M, Kawakami S, Yamazaki S, Hatta T, Sugiyama Y.


Combination chemotherapy with low-dose 5-FU, cisplatin, and gemcitabine for gemcitabine-refractory pancreatic cancer.
Shinshu Med J,57:247-253 2009
Author:Arakura N, Hasebe O, Ochi Y, Hamano H, Yanaka E, Kawa S


Granulocyte-colony stimulating factor-producing pancreatic adenosquamous carcinoma showing aggressive clinical course.
Intern Med,48(9):681-691 2009
Author:Joshita S, Nakazawa K, Sugiyama Y, Kamijo A, Matsubayashi K, Miyabayashi H, Furuta K, Kitano K, Kawa S


Long-Term Follow-Up of Autoimmune Pancreatitis: Characteristics of Chronic Disease and Recurrence.
Clinical Gastroenterology and Hepatology,7(11):S18-S22 2009
Author:Kawa S, Hamano H, Ozaki Y,Ito T, Kodama R, Chou Y, Takayama M, Arakura N.


Combination Chemotherapy with Low-dose 5-FU, Cisplatin, and Gemcitabine for Gemcitabine-Refractory Pancreatic Cancer
信州医学雑誌,57(6):247-253 2009
Author:Norikazu ARAKURA, Osamu HASEBE, Yasuhide OCHI, Hideaki HAMANO, Eiji TANAKA, Shigeyuki KAWA
Keywords:second-lin chemotherapy, pancreatic cancer, 5-FU, Cisplatin, Gemcitabine


Abscess of the round ligament of the liver associated with acute obstructive cholangitis and septic thrombosis.
Intern Med,48(21):1885-8 2009
Author:Arakura N, Ozaki Y, Yamazaki S, Ueda K, Maruyama M, Chou Y, Kodama R, Takayama M, Hamano H, Tanaka E, Kawa S.


Pancreaticobiliary fistula evident after ESWL treatment of pancreatolithiasis.
Intern Med,48(7):545-9 2009
Author:Arakura N, Ozaki Y, Maruyama M, Chou Y, Kodama R, Takayama M, Hamano H, Tanaka E,Kawa S.


Japanese clinical guidelines for autoimmune pancreatitis.
Pancreas,38:849-66 2009
Author:Okazaki K, Kawa S, Kamisawa T, Ito T, Inui K, Irie H, Irisawa A, Kubo K, Notohara K, Hasebe O, Fujinaga Y, Ohara H, Tanaka S, Nishino T, Nishimori I, Nishiyama T, Suda K, Shiratori K, Shimosegawa T, Tanaka M.


Association analysis of Toll-like receptor 4 polymorphisms with autoimmune pancreatitis
Hum Immunol 2009
Author:Umemura T, Katsuyama Y,Hamano H, Kitahara K, Takayama M, Arakura N, Kawa S, Tanaka E, Ota M


Pulmonary involvement of autoimmune pancreatitis.
Eur J Clin Invest,39:714-22 2009
Author:Tsushima K, Tanabe T, Yamamoto H, Koizumi T, Kawa S, Hamano H, Honda T, Uehara T, Kawakami S, Kubo K.


Efficacy of preoperative endoscopic nasobiliary drainage for hilar cholangiocarcinoma.
J Hepatobiliary Pancreat Surg,16:473-7 2009
Author:Arakura N, Takayama M, Ozaki Y, Maruyama M, Chou Y, Kodama R, Ochi Y, Hamano H, Nakata T, Kajikawa S, Tanaka E, Kawa S.


Central airway stenosis in a patient with autoimmune pancreatitis.
Eur Respir J,33:680-3 2009
Author:Ito M, Yasuo M, Yamamoto H, Tsushima K, Tanabe T, Yokoyama T, Hamano H, Kawa S, Uehara T, Honda T, Kawakami S, Kubo K.


Small cell carcinoma of the extrahepatic bile duct diagnosed with EUS-FNA and effectively treated with chemoradiation
Intern Med,47:621-5 2008
Author:Arakura N, Muraki T, Komatsu K, Ozaki Y, Hamano H, Tanaka E, Kawa S


Microsatellite scan identifies new candidate genes for susceptibility to alcoholic chronic pancreatitis in japanese patients
Dis Markers,25:175-80 2008
Author:Kitahara K, Kawa S, Katsuyama Y,Umemura T, Ozaki Y, Takayama M, Arakura N, Ota M


Conference report: Korea-Japan symposium on autoimmne pancreatitis
Gut and Liver,2:81-87 2008
Author:Park SW, Chung JB, Otsuki M, Kim MH, Lim JH, Kawa S, Ito T, Ryu JK, Okazaki K, Lee K, Kamisawa T


Autoimmune pancreatitis-associated prostatitis: distinct clinicopathological entity
Pathol Int,58:118-25 2008
Author:Uehara T, Hamano H, Kawakami M, Koyama M, Kawa S, Sano K, Honda T, Oki K, Ota H


A novel immunoglobulin-immunoglobulin interaction in autoimmunity
PLoS ONE,3(2):e1637 2008
Author:Kawa S, Kitahara K, Hamano H, Ozaki Y, Arakura N, Yoshizawa K, Umemura T, Ota M, Mizoguchi S, Shimozuru Y, Bahram S


Research Committee of Intractable Pancreatic Diseases provided by the Ministry of Health, Labour and Welfare of Japan and the Korean Society of Pancreatobiliary Diseases
J Gastroenterol Asian diagnostic criteria for autoimmune pancreatitis: consensus of the Japan-Korea Symposium on Autoimmune Pancreatitis,(4):403-8 2008
Author:Otsuki M, Chung JB, Okazaki K, Kim MH, Kamisawa T, Kawa S, Park SW, Shimosegawa T, Lee K, Ito T, Nishimori I, Notohara K, Naruse S, Ko SB, Kihara Y


Diagnosticcriteria for autoimmune pancreatitis in Japan
World J Gastroenterol,28(14):4992-4 2008
Author:Kamisawa T, Okazaki K, Kawa S


Association of autoimmune pancreatitis with cytotosic T-lymphocyte antigen 4 gene polymorphism in Japanese patients
Am J Gastroenterol,103(3):588-94 2008
Author:Umemura T, Ota M, Hamano H, Katsuyama Y, Muraki T, Arakura N, Kawa S, Kiyosawa K


Pancreatic exocrine insufficiency: A rare cause of nonalcoholic steatohepatitis
AMERICAN JOURNAL OF GASTROENTEROLOGY,103(1):245-246 2008
Author:Tanaka, N; Horiuchi, A; Yokoyama, T; Kawa, S; Kiyosawa, K


Differentiation of autoimmune pancreatitis from suspected pancreatic cancer by fluorine-18 fluorodeoxyglucose positron emission tomography
JOURNAL OF GASTROENTEROLOGY,43(2):144-151 2008
Author:Ozaki, Y; Oguchi, K; Hamano, H; Arakura, N; Muraki, T; Kiyosawa, K; Momose, M; Kadoya, M; Miyata, K; Aizawa, T; Kawa, S


IgG4-related autoimmune prostatitis: two cases with or without autoimmune pancreatitis
Intern Med,46:1983-9 2007
Author:Nishimori I, Kohsaki T, Onishi S, Shuin T, Kohsaki S, Ogawa Y, Matsumoto M, Hiroi M, Hamano H, Kawa S


Japan-Korea symposium on autoimmune pancreatitis
Pancreas KOKURA 2007,35:281-4 2007
Author:Kamisawa T, Chung JB, Irie H, Nishino T, Ueki T, Takase M, Kawa S, Nishimori I, Okazaki K, Kim MH, Otsuki M.


Inflammatory lesions of the lung, submandibular gland, bile duct and prostate in a patient with IgG4-associated multifocal systemic fibrosclerosis
Respirology,12:455-457 2007
Author:Hamed G, Tsushima K, Yasuo M, Kubo K, Yamazaki S, Kawa S, Hamano H, Yamamoto H


Sclerosing Cholangitis Associated with Autoimmune Pancreatitis
Hepatology Res,37(Suppl3):487-495 2007
Author:Kawa S, Hamano H, Umemura T, Kiyosawa K, Uehara T


IgG4-Hepatopathy: Association of IgG4-Bearing Plasma Cells in Liver with Autoimmune Pancreatitis. Hepatology
,46:463-471 2007
Author:Umemura T, Zen Y, Hamano H, Kawa S, Nakanuma Y, Kiyosawa K


Clinical features of autoimmune pancreatitis
J Gastroenterol,42(Suppl18):9-14 2007
Author:Kawa S, Hamano H


A genomewide DNA microsatellite association study of Japanese patients with autoimmune hepatitis type 1
Hepatology,45:384-390 2007
Author:Yokosawa S, Yoshizawa K, Ota M, Katsuyama Y, Kawa S, Ichijo T, Umemura T,Tanaka E, Kiyosawa K


IgG4-associated multifocal systemic fibrosis presenting with fever of unknown origin
Oxford Journal Med,100:141-145 2007
Author:Tsushima K, Hamano H, Kawa S, Kubo K


Two critical genes (HLA-DRB1 and ABCF1)in the HLA region are associated with the susceptibility to autoimmune pancreatitis
Immunogenetics,59:45-52 2007
Author:Ota M, Katsuyama Y, Hamano H, Umemura T, Kimura A, Yoshizawa K, Kiyosawa K, Fukushima H, Bahram S, Inoko H, Kawa S


IgG4 associated autoimmune hepatitis: a differential diagnosis for classical autoimmune hepatitis
GUT,56(10):1471-1472 2007
Author:Umemura,T; Zen, Y; Hamano, H; Ichijo, T; Kawa, S; Nakanuma, Y; Kiyosawa, K


Seronegative Sjogren syndrome with asymptomatic autoimmune sclerosing pancreatitis
CLINICAL RHEUMATOLOGY,26(1):117-119 2007
Author:Matsuda, M; Hamano, H; Yoshida, T; Gono, T; Uehara, T; Kawa, S; Ikeda, S


Lack of association between FCRL3 and Fc gamma RII polymorphisms in Japanese type 1 autoimmune hepatitis
Clinical Immunology,122(3):338-342 2007
Author:Umemura, T; Ota, M; Yoshizawa, K; Katsuyama, Y; Ichijo, T; Tanaka, E; Kawa, S; Kiyosawa, K


IgG4-related sclerosing cholangitis should be included as an exclusion criterion for the diagnosis of primary sclerosing cholangitis
Am J Gastroenterol,102(3):691-692 2007
Author:Hamano, H; Umemura, T; Uehara, T; Kawa, S; Kiyosawa, K


Pancreatitis. In: Rose NR, MacKay IR (ed), The autoimmune diseases
,:779-86 2006
Author:Kawa S, Hamano H, Kiyosawa K


IgG4-associated multifocal systemic fibrosis complicating sclerosing sialadenitis, hypophysitis, and retroperitoneal fibrosis, but lacking pancreatic involvement
Intern Med,45:1243-1247 2006
Author:Tanabe T, Tsushima K, Yasuo M, Urushihata K, Hanaoka M, Koizumi T, Fujimoto K, Kubo K, Uehara T, Shigematsu S, Hamano H, Kawa S


Are there any other organs in which autoimmune pancreatitis -associated lesions remain to be identified?
Intern Med,45:883-884 2006
Author:Hamano H, Kawa S


Autoimmune pancreatitis and complement activation system
PANCREAS,32(1):16-21 2006
Author:Muraki, T; Hamano, H; Ochi, Y; Komatsu, K; Komiyama, Y; Arakura, N; Yoshizawa, K; Ota, M; Kawa, S; Kiyosawa, K


Clinical utility of quantitative RT-PCR targeted to alpha 1,4-N-acetylglucosaminyltransferase mRNA for detection of pancreatic cancer
CANCER SCIENCE,97(2):119-126 2006
Author:Ishizone, S; Yamauchi, K; Kawa, S; Suzuki, T; Shimizu, F; Harada, O; Sugiyama, A; Miyagawa, S; Fukuda, M; Nakayama, J


Lysocellin, a metabolite of the novel drug 'alopestatin', induces G1 arrest and prevents cytotoxicity induced by etoposide
INTERNATIONAL JOURNAL OF ONCOLOGY,28(4):823-829 2006
Author:Takahara, Y; Yogosawa, S; Maruyama, S; Watanabe, N; Yokoyama, H; Fukasawa, K; Sukenaga, Y; Kamiyama, J; Izumi, M; Wakada, M; Zhang, HL; Yoshizawa, K; Kawa, S; Nikaido, T; Sakai, T


Consensus of primary care in acute pancreatitis in Japan
WORLD JOURNAL OF GASTROENTEROLOGY,12(21):3314-3323 2006
Author:Otsuki, M; Hirota, M; Arata, S; Koizumi, M; Kawa, S; Kamisawa, T; Takeda, K; Mayumi, T; Kitagawa, M; Ito, T; Inui, K; Shimosegawa, T; Tanaka, S; Kataoka, K; Saisho, H; Okazaki, K; Kuroda, Y; Sawabu, N; Takeyama, Y


Clinical diagnostic criteria of autoimmune pancreatitis: revised proposal
JOURNAL OF GASTROENTEROLOGY,41(7):626-631 2006
Author:Okazaki, K; Kawa, S; Kamisawa, T; Naruse, S; Tanaka, S; Nishimori, I; Ohara, H; Ito, T; Kiriyama, S; Inui, K; Shimosegawa, T; Koizumi, M; Suda, K; Shiratori, K; Yamaguchi, K; Yamaguchi, T; Sugiyama, M; Otsuki, M


Spontaneous excretion of a pancreatic stone found in a patient with pancreas divisum
PANCREAS,33(2):203-205 2006
Author:Okubo, K; Maruyama,M; Nagaya, T; Tomita, T; Kamijo, H; Kobayashi, N; Mochizuki, T; Okubo, H; Kawa, S


Influence of steroid therapy on the course of diabetes mellitus in patients with autoimmune pancreatitis - Findings from a nationwide survey in Japan
PANCREAS,32(3):244-248 2006
Author:Nishimori, I; Tamakoshi, A; Kawa, S; Tanaka, S; Takeuchi, K; Kamisawa, T; Saisho, H; Hirano, K; Okamura, K; Yanagawa, N; Otsuki, M


Genetic association of Fc receptor-like 3 polymorphisms with autoimmune pancreatitis in Japanese patients
GUT,55(9):1367-1368 2006
Author:Umemura, T; Ota, M; Hamano, H; Katsuyama, Y; Kiyosawa, K; Kawa, S


Prevalence and distribution of extrapancreatic lesions complicating autoimmune pancreatitis
J Gastroenterol,41(12):1197-1205 2006
Author:Hamano, H; Arakura, N; Muraki, T; Ozaki, Y; Kiyosawa, K; Kawa, S


Seronegative Sjogren syndrome with asymptomatic autoimmune sclerosing pancreatitis
Clin Rheumatol,15:1-3 2005
Author:Matsuda M, Hamano H, Yoshida T, Gono T, Uehara T, Kawa S, Ikeda S


Distinct clinicopathological entity 'autoimmune pancreatitis-associated sclerosing cholangitis'
PATHOLOGY INTERNATIONAL,55(7):405-411 2005
Author:Uehara, T; Hamano, H; Kawa, S; Sano, K; Honda, T; Ota, H


Immunoglobulin G4-related lymphoplasmacytic sclerosing cholangitis that mimics infiltrating hilar cholangiocarcinoma: part of a spectrum of autoimmune pancreatitis?
GASTROINTESTINAL ENDOSCOPY,62(1):152-157 2005
Author:Hamano, H; Kawa, S; Uehara, T; Ochi, Y; Takayama, M; Komatsu, K; Muraki, T; Umino, J; Kiyosawa, K; Miyagawa, S


Corticosteroid-responsive pancreatic cyst found in autoimmune pancreatitis
JOURNAL OF GASTROENTEROLOGY,40(7):761-766 2005
Author:Muraki, T; Hamano, H; Ochi, Y; Arakura, N; Takayama, M; Komatsu, K; Komiyama, Y; Kawa, S; Uehara, T; Kiyosawa, K


Inhibitory effect of 22-oxa-1,25-dihydroxyvitamin D-3, maxacalcitol, on the proliferation of pancreatic cancer cell lines
Journal of Steroid Biochemistry and Molecular Biology,97(1-2):173-177 2005
Author:Kawa, S; Yoshizawa, K; Nikaido, T; Kiyosawa, K


High prevalence of hypothyroidism in patients with autoimmune pancreatitis
Dig Dis Sci,50(6):1052-1057 2005
Author:Komatsu, K; Hamano, H; Ochi, Y; Takayama, M; Muraki, T; Yoshizawa, K; Sakurai, A; Ota, M; Kawa, S


Chronic pancreatitis associated with adult-onset type II citrullinemia: clinical and pathologic findings
Ann Intern Med,141:W109-10 2004
Author:Ikeda S, Kawa S, Takei Y, Yamamoto K, Shimojo H, Tabata K, Kobayashi K, Saheki T


Recurrent Attacks of Autoimmune Pancreatitis Result in Pancreatic Stone Formation
American Journal of Gastroenterology,99(5):932-937 2004
Author:Mari Takayama, Hideaki Hamano, Yasuhide Ochi, Hisanobu Saegusa, Kenichi Komatsu, Takashi Muraki, Norikazu Arakura, Yasuharu Imai Osamu Hasebe and Shigeyuki Kawa M.D. 1)


Autoimmune Pancreatitis is Closely Associated with Gastric Ulcer Presenting with Abundant IgG4-bearing Plasma Cell Infiltration
Gastrointestinal Endoscopy,59(4):506-511 2004
Author:Akihiro Shinji, MD., Kenji Sano, MD.,Hideaki Hamano, MD., Hiroshi Unno, MD., Mana Fukushima, MD., Naoshi Nakamura, MD., Taiji Akamatsu, MD., Shigeyuki Kawa, MD., Kendo Kiyosawa, MD


Autoimmune pancreatitis and bile duct lesions
JOURNAL OF GASTROENTEROLOGY,38(12):1201-1203 2003
Author:Kawa, S; Hamano, H


Human amnion-isolated cells normalize blood glucose in streptozotocin-induced diabetic mice
Cell Transplant,12(5):545-552 2003
Author:Wei JP, Zhang TS,Kawa S, Aizawa T, Ota M, Akaike T, Kato K, Konishi I, Nikaido T


Hilar and pancreatic gallium-67 accumulation is characteristic feature of autoimmune pancreatitis
Pancreas,27(1):20-25 2003
Author:Saegusa H, Momose M, Kawa S, Hamano H, Ochi Y, Takayama M, Kiyosawa K, Kadoya M


Hydronephrosis associated with retroperitoneal fibrosis and sclerosing pancreatitis
LANCET,359(9315):1403-1404 2002
Author:Hamano, H; Kawa, S; Ochi, Y; Unno, H; Shiba, N; Wajiki, M; Nakazawa, K; Shimojo, H; Kiyosawa, K


Growth inhibition and differentiation of pancreatic cancer cell lines by PPAR gamma ligand troglitazone.
Pancreas,24(1):1-7 2002
Author:Kawa S, Nikaido T, Unno H, Usuda N, Nakayama K, Kiyosawa K


Extracorporeal shock wave lithotripsy of pancreatic duct stones and patient factors related to stone disintegration
J Gastroenterol,37(5):369-375 2002
Author:Karasawa Y, Kawa S, Aoki Y, Ochi Y, Unno H, Kiyosawa K, Watanabe T


Development of highly sensitive RIA for somatostatin: direct measurement of plasma somatostatin in humans, monkeys and rats
Clin Pediatr Endocrinol,11:99-105 2002
Author:Katakami H, Hidaka H, Yonekawa T, Kawa S, Shimizu K, Matsukura S


Peroxisome proliferator-activated receptor gamma ligand troglitazone induces cell cycle arrest and apoptosis of hepatocellular carcinoma cell lines
Cancer,95(10):2243-2251 2002
Author:Yoshizawa K, Cioca DP, Kawa S, Tanaka E, Kiyosawa K


A primary Sjogren's syndrome patient with marked swelling of multiple exocrine glands and sclerosing pancreatitis
Internal Medicine,41(9):749-753 2002
Author:Akahane, C. Takei, Y. Horiuchi, A. Kawa, S. Nishimura,K.&Ikeda,S


ERCP features in 27 patients with autoimmune pancreatitis
Gastrointest Endosc,55(4):494-499 2002
Author:Horiuchi A, Kawa S, Hamano, H. Hayama, M. Ota, H.&Kiyosawa, K


Does a lack of reactivity to alpha-fodrin indicate the existence of primary autoimmune pancreatitis?
Am J Gastroenterol,97(5):1275-1277 2002
Author:Horiuchi, A. Kawa, S. Hamano, H. Hayashi, Y.&Kiyosawa, K.


HLA DRB1*0405-DQB1*0401 haplotype is associated with autoimmune pancreatitis in the Japanese population.
Gastroenterology,122(5):1264-1269 2002
Author:kawa S. Ota, M. Yoshizawa, K. Horiuchi, A. Hamano, H. Ochi, Y. Nakayama, K. Tokutake, Y. Katsuyama, Y. Saito, S. Hasebe, O.&Kiyosawa, K


Sclerosing pancreatitis complicated with hydronephrosis caused by retroperitoneal fibrosis. (in press).
Lancet,359:1403-1404 2002
Author:Hamano H, Kawa S, Ochi Y, Kiyosawa K, et al.,


Growth inhibition of panc- reatic cancer cell lines by ligand activation of nuclear hormone receptors through up-reguration of WAF1/CIP1/p21、Asakura H, Aoyagi Y, Nakazawa S(ed)
Trends in Gastroenterology and hepatology,:147-152 2001
Author:Kawa S, Kiyosawa K


Insulin and somatostatin releasing islet cell tumor caused hypoglycemia
INTERNAL MEDICINE,40(4):324-330 2001
Author:Karasawa, Y; Mochizuki, T; Kawa, S; Aoki, Y; Ueno, T;Watanabe, T; Kawasaki, S; Miyagawa, S; Itoh, N; Tamai, C; Sakurai, A; Kiyosawa, K


High serum IgG4 concentrations in patients with sclerosing pancreatitis. Reply
NEW ENGLAND JOURNAL OF MEDICINE,345(2):148-148 2001
Author:Kawa, S; Hamano, H; Kiyosawa, K


Duodenal somatostatinoma and erythrocytosis in a patient with von Hippel-Lindau disease type 2A
Intern Med,40(1):38-43 2001
Author:Karasawa Y, Sakaguchi M, Minami S, Kitano K, Kawa S, Aoki Y, Itoh N, Sakurai A


Hepatocarcinogenesis inhibition by caffeine in ACI rats treated with 2-acetylaminofluorene
Food Chem Toxicol,39(6):557-561 2001
Author:Hosaka S, Kawa S, Aoki Y, Tanaka E, Yoshizawa K, Karasawa Y, Hosaka N,Kiyosawa K


Potential tumor-targeting peptide vector of histidylated oligolysine conjugated to a tumor-homing RGD motif
Cancer Gene Ther,8(10):783-787 2001
Author:Aoki Y, Hosaka S, Kawa S, Kiyosawa K


Sclerosing pancreato-cholangitis responsive to corticosteroid therapy: report of 2 case reports and review
Gastrointestinal Endoscopy,53(4):518-522 2001
Author:Horiuchi A, Kawa S, Hamano H, Ochi Y, Kiyosawa K


High serum IgG4 concentrations in patients with sclerosing pancreatitis.
New Engl J Med,344(10):732-738 2001
Author:Hamano H, Kawa S, Horiuchi A, et al.,


Clinicopathological features of 22 Japanese patients with autoimmune pancreatitis.
GASTROENTEROLOGY,118(4):A422-A422 2000
Author:Horiuchi, A; Kawa, S; Hamano, H; Akamatsu, T; Fujii, H; Kiyosawa, K


Reassessment of K-ras mutations at codon 12 by direct PCR and sequencing from tissue microdissection in human pancreatic adenocarcinomas
Pancreas,21(2):152-157 2000
Author:Aoki Y, Hosaka S, Tachibana N, Karasawa Y, Kawa S, Kiyosawa K


Retinoic acid is a negative regulator for the differentiation of cord blood-derived human mast cell progenitors
Blood,95(9):2821-2828 2000
Author:Kinoshita T, Koike K, Mwamtemi HH, Ito S, Ishida S, Nakazawa Y, Kurokawa Y, Sakashita K, Higuchi T, Takeuchi K, Sawai N, Shiohara M, Kamijjo T, Kawa S, Yamashita T, Komiyama A


Glucagonoma presenting with pancreatitis and a pseudocyst-like lesion communicating with a main pancreaticduct
Gastrointestinal Endoscopy,51(1):80-82 2000
Author:Hamano H, Kawa S, Mukawa K, Usui T, Shinji A, Shimada R, Miyagawa S, Kawasaki S


Endoscopic pancreatic sphincter balloon dilation for effective retrieval of pancreatic duct stone
J of Gastroenterology and Hepatology,15(2):220-224 2000
Author:Suga T, Kawa S,Horiuchi A, Nakamura N. Mukawa K, Akamatsu T, Kiyosawa K


Hypocalcemia<7.5 mg/dl: early predictive marker for multisystem organ failure in severe acute necrotizing pancreatitis, proposed by the study analyzing post-ERCP pancreatitis.
Am J Gastroenterol,95(4):1096-1097 2000
Author:Kawa S, Mukawa K, Kiyosawa K.,


A clinicopathological study of autoimmune pancreatitis
GASTROENTEROLOGY,116(4):A1134-A1134 1999
Author:Horiuchi, A; Kawa, S; Hamano, H


Reduced expression of p53 and cyclin A in intraductal mucin-hypersecreting neoplasm of the pancreas compared with usual pancreatic ductal adenocarcinoma.
Am J Gastroenterol,94(8):2263-2267 1999
Author:Mukawa K, Kawa S, et al.,


A case of glycogen storage disease type Ia with multiple hepatic adenomas and G727T mutation in the glucose-6-phosphatase gene, and a comparison with other mutations previously reported
Am J of Gastroenterol,93(9):1550-1553 1998
Author:42. Karasawa Y, Kobayashi M, Nakano Y, Aoki Y, Kawa S, Kiyosawa K, Kawasaki S,Furihata


Anti-proliferative effects of unmodified antisense oligodeoxynucleotides targeted against c-raf mRNA: Use of poly (lysine/serine) copolymers or cationic lipopolyamines
Clinical and Experimental Pharmacology and Physiology,25(9):702-705 1998
Author:Aoki Y, Kawa S, Karasawa Y, Horiuchi A, Kiyosawa K


Malignant insulinoma presenting a non-functioning metastatic livertumor 14 years after resection of the primary tumor
J of Gastroenterology,33(6):891-894 1998
Author:Kobayashi, M; Kawa, S; Kobayashi, M; Imai, Y; Sodeyama, T; Kiyosawa, K


Establishment of a GM-CSF-dependent megakaryoblastic cell line with the potential to differentiate into an eosinophilic lineage in response to retinoic acids
Br J Haematology,100(2):427-435 1998
Author:Ma F, Koike K, Higuchi T, Kinoshita T, Takeuchi K, Mwamtei HH, Sawai N, Kamijyo T, Shiohara M, Horie S, Kawa S, Sasaki Y, Hidaka E, Yamagami O, Yamashita T, Koike T, Ishii E, Komiyama A


Characteristic pancreatic duct appearance in autoimmune chronic pancreatitis: A case report and review of the Japanese literature
Am J of Gastroenterology,93(2):260-263 1998
Author:Horiuchi A, Kawa S, Akamatsu T, Aoki Y, Mukawa K, Furuya N, Ochi Y, Kiyosawa K


Levels of fructosyllysine in collagen are low compared with the loss of lysine in diabetic rats: Involvement of oxidation in increased cross-linking
Clinical and Experimental Pharmacology and Physiology,24(9-10):657-660 1997
Author:Aoki Y, Karasaw Y, Yazaki K, Shiratori K, Kawa S, Kiyosawa K


Growth hormone-releasing hormone (GRH)-producing pancreatic tumor with no evidence of multiple endocrine neoplasia type 1
Dig Dis Sci,42(7):1480-1485 1997
Author:Kawa S, Ueno T, IIjima A, Midorikawa T, Fujimori Y, Tokoo M, Oguchi H, Kiyosawa K, Imai Y, Kaneko G, Kuroda T, Hashizume K, Osamura, Katakami H


Arotinoid mofarotene (RO40-8757) up-regulates p21 and p27 during growth inhibition of pancreatic cancer cell lines
Int J Cancer,72(5):906-911 1997
Author:Kawa S, et al.,


Long-term follow-up of patients with chronic pancreatitis and K-ras gene mutation detected in pancreatic juice
Gastroenterology,113(2):593-598 1997
Author:Furuya N, Kawa S, Furihata K


Inhibition of chemotactic motility and trans-endotherial migration of human neutrophils by sphingosine 1-phosphate
FEBS Letter,420:196-200 1997
Author:Kawa S et al.,


Vitamin D analogues up-regulate p21 and p27 during growth inhibition of pancreatic cancer cell lines
Br J Cancer,76(7):884-889 1997
Author:Kawa S,et al.,


Autoimmune chronic pancreatitis simulating pancreatic lymphoma
Am J Gastroenterol,91(12):2607-2609 1996
Author:Horiuchi A, Kaneko T, Yamamura N, Nagata A, Nakamura T, Akamatsu T, Kawa S, Kiyosawa K


The relationship between drinking status and serialchanges of pancreatographic findings in patients with suspected early chronic alcoholic pancreatitis
Pancreas,13(2):209-214 1996
Author:Maejima, SY; Kawa, S; Hasebe, O; Homma, T


Continuous hemofiltration as an effective treatment in two cases of severe acute pancreatitis
Jpn J Apheresis,15:134-136 1996
Author:Tokoo M, Kobayashi M, Shirotori K, Hayashi K, Higuchi M, Hora K, Kawa S, Arakura H, Oguchi H, Kiyosawa K


Comparative study of CA242 and CA19-9 in chronic pancreatitis
Br J Cancer,73(3):372-376 1996
Author:Furuya N, Kawa S, Hasebe O, Tokoo M, Mukawa K, Maejima S, Oguchi H


Inhibitory effect of 22-oxa-1,25- dihydroxyvitamin D3 on the proliferation of pancreatic cancer cell lines.
Gastroenterology,110(5):1605-1613 1996
Author:Kawa et al.,


Double anastomoses to jejunum of dissected pancreas portions in pancreas divisum
J Hep Bil Pancr Surg,2:279-283 1995
Author:Furusawa T, Kuroda T, Nakata S, Kaneko G, Kawa S, Hasebe O, Tokoo M


Liposomal N,N,N-trimethylsphingosine (TMS) as an inhibitor of B16 melanoma cell growth and metastasis with reduced toxicity and enhanced drug efficacy compared tofree TMS: cell membrane signaling as a target in cancer therapy III
Cancer Res,54:2213-2217 1994
Author:Park YS, Hakomori S, Kawa S, Ruan F, Igarashi Y


COMPARATIVE-STUDY OF CA242 ANDCA19-9 FORTHE DIAGNOSIS OF PANCREATIC-CANCER
BRITISH JOURNAL OF CANCER,70(3):481-486 1994
Author:KAWA, S; TOKOO, M; HASEBE, O; HAYASHI, K; IMAI, H;OGUCHI, H; KIYOSAWA, K; FURUTA, S; HOMMA, T


EPITOPE ANALYSIS OF SPAN-1 AND DUPAN-2 USING SYNTHESIZED GLYCOCONJUGATES SIALYLLACT-N-FUCOPENTAOSE-II AND SIALYLLACT-N-TETRAOSE
PANCREAS,9(6):692-697 1994
Author:KAWA, S; TOKOO, M; OGUCHI, H; FURUTA, S; HOMMA, T; HASEGAWA, Y; OGATA, H; SAKATA, K


EXPRESSION OF GLYCOCONJUGATES IN PANCREATIC, GASTRIC, AND COLONIC TISSUE BY BAUHINIA-PURPUREA, VICIA-VILLOSA, AND PEANUT LECTINS
SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY,28(7):599-604 1993
Author:SHUE, GL; KAWA, S; KATO, M; OGUCHI, H; KOBAYASHI, T; KOIWAI, T; TOKOO, M; FURUTA, S; KANAI, M; HOMMA, T


EFFECTS OF THE S2-SEROTONERGIC RECEPTOR ANTAGONIST, KETANSERIN, ON CERULEIN-INDUCED PANCREATITIS IN THE RAT
LIFE SCIENCES,50(10):733-737 1992
Author:OGUCHI, H; TERASHIMA, M; KOIWAI, T; KAWA, S; FURUTA, S; KOBAYASHI, M; HOMMA, T


EOSINOPHILIA ASSOCIATED WITH CHRONIC-PANCREATITIS - AN ANALYSIS OF 122 PATIENTS WITH DEFINITE CHRONIC-PANCREATITIS
AMERICAN JOURNAL OF GASTROENTEROLOGY,87(4):455-460 1992
Author:TOKOO, M; OGUCHI, H; KAWA, S; HOMMA, T; NAGATA, A


CLINICAL-EVALUATION OF PANCREATIC CANCER-ASSOCIATED MUCIN EXPRESSING CA19-9, CA50, SPAN-1, SIALYL SSEA-1, AND DUPAN-2
SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY,27(8):635-643 1992
Author:KAWA, S; KATO, M; OGUCHI, H; HSUE, GL; KOBAYASHI, T; KOIWAI, T; TOKOO, M; FURUTA, S; ICHIKAWA, T; KANAI, M


COMPARATIVE-STUDY OF CA-50 (TIME-RESOLVED FLUOROIMMUNOASSAY), SPAN-1, AND CA19-9 IN THE DIAGNOSIS OF PANCREATIC-CANCER
SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY,26(7):787-797 1991
Author:KOBAYASHI, T; KAWA, S; TOKOO, M; OGUCHI, H; KIYOSAWA, K; FURUTA, S; KANAI, M; HOMMA, T


ELEVATION OF SERUM CA-19-9 IN PARALLEL WITH HBA1C IN A DIABETIC FEMALE WITH THE LEWIS(A+B-) BLOOD-GROUP
DIABETES RESEARCH AND CLINICAL PRACTICE,13(1-2):77-81 1991
Author:AOKI, Y; YANAGISAWA, Y; OHFUSA, H; KAWA, S; OGUCHI, H; FURUTA, S


PREPARATION OF PANCREATIC CANCER-ASSOCIATED MUCIN EXPRESSING CA19-9, CA50, SPAN-1, SIALYL SSEA-1, AND DUPAN-2
SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY,26(9):981-992 1991
Author:KAWA, S; KATO, M; OGUCHI, H; KOBAYASHI, T; FURUTA, S; KANAI, M


ELEVATED SERUM LEVELS OF DUPAN-2 IN PANCREATIC-CANCER PATIENTS NEGATIVE FOR LEWIS BLOOD-GROUP PHENOTYPE
BRITISH JOURNAL OF CANCER,64(5):899-902 1991
Author:KAWA, S; OGUCHI, H; KOBAYASHI, T; TOKOO, M; FURUTA, S; KANAI, M; HOMMA, T


PREPARATION AND PARTIAL CHARACTERIZATION OF A PANCREATIC CANCER-ASSOCIATED GLYCOPROTEIN EXPRESSING CA50
SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY,26(12):1307-1318 1991
Author:KAWA, S; KATO, M; OGUCHI, H; KOBAYASHI, T; HSUE, GL; KOIWAI, T; AOKI, Y; FURUTA, S; KANAI, M


A comparative study of CA19-9, CA50, sialylSSEA-1 and Dupan-2for the diagnosis of pancreatic cancer used alone or in combination
Jpn J Clin Chem,19:389-398 1990
Author:Kawa S, Oguchi H, Tokoo M, Kobayashi T, Imai H, Kiyosawa K, Furuta S, Kanai M, Homma T


The role of oxygen free radicals in experimental acute pancreatitis in rat
Int J Pancreatol,5:135-143 1989
Author:Koiwai T, Oguchi H, Kawa S, Yanagisawa, Kobayashi T, Homma T


Comparative study of chronic alcoholic pancreatitis in exocrine pancreatic function, pancreatic duct system. In: Kameda T, Kuruyama K, Suwaki H (ed), Biomedical aspects of alcohol and alcoholism
,:363-369 1988
Author:Homma T, Oguchi H, KawaS, Furuta S, Nagata A


Oxigen free radicals in experimental acute pancreatitis in rat. In: Tsuchiya M (ed), Free radicals in Digestive Diseases
,:209-214 1988
Author:Koiwai T, Oguchi H, Kawa S, Yanagisawa Y, Furuta S, Homma T, Nagata A


Long-term follow-up of patients with sich sinus syndrome: a comparison of clinical aspects among unpaced, ventricular inhibited paced, and physiologically paced groups
Pace,11:1575-1583 1988
Author:Sasaki Y , Shimotori M, Akahane K, Yonekura H, Hirano K, Endoh R, Koike S, Kawa S, Furuta S, Homma T


Left atrial myxoma with an unusual tumor vascularity demonstrated by angiography
Jap Circ J,52:89-93 1988
Author:Endoh R , Akahane K, Hirano K, Yonekura H, Koike S, Kawa S, Sasaki Y, Furuta S, Suyama K, Furihata Y, Yoshizawa S


Familial dilated cardiomyopathy and human leucocyte antigen, A report of two family cases
Jpn Heart J,28:941-945 1987
Author:Koike S, Kawa S, Yabu K, Endoh R, Sasaki Y, Furuta S, Ota M


Loss of Lewis antigen expression on erythrocytes in some cancer patients with high serum CA19-9 levles
J Natl Cancer I,79:1261-1268 1987
Author:Hirano K, Kawa S, Oguchi H, Kobayashi T, Yonekura H, Ogata H, Homma T


Study of chronic alcoholic pancreatitis by means of serial pancreozymin-secretin tests
Digestion,33:135-145 1986
Author:Nagata A, Homma T,Oguchi H, Tamura Y, Hirabayashi H, Sasaki Y, Kawa S, Monno S, Shimakura K, Shirai T, Furuta S


Exocrine pancreatic function in asymptomatic chronic alcoholics without structual pancreatic disease
Gastroenterol Jpn,20:125-130 1985
Author:Nagata A, Homma T, Ueno K, Shimakura K, Oguchi H, Tamura Y, Hirabayashi, H, Kawa S, Furuta S


Immunoperoxidase detection of pancreatic oncofetal antigen in human tissues
Gastroenterol Jpn,20:361-367 1985
Author:Kawa S


A pancreatic oncofetal antigen- its characterization and pplication for enzyme immunoasssay
Cancer Detec Preven,7:51-58 1984
Author:Oguchi H, Homma T, Kawa S, Nagata A, Furuta S, Fukui H


Exocrine pancreatic cancer with humoral hyper calcemia
Am J Gastroenterol,(79):128-132 1984
Author:Monno S, Nagata A, Homma T, Oguchi H, Kawa S, Kaji R, Furuta S


Clinical application of the enzyme immunoassay for pancreatic oncofetal antigen
Fufui H: , Ann N Y Acad Sci,(417):400-409 1983
Author:Kawa S, Homma T, Oguchi H, Nagata A, Furuta S, Usuda N, Nagata T


Serum pancreatic oncofetal antigen: its clinical usefulness for screening pancreatic cancer in combination with tests for other tumor markers
Gastroenterol Jpn,5:487-491 1983
Author:Homma T, Oguchi H, Kawa S, Nagata A, Furuta S


A pancreatic oncofetal antigen: its partial purification and clinical application
Gastroenterol Jpn,16:268-274 1981
Author:Homma T, Oguchi H, Kawa S

研究費
受託研究
2003 - 2005 , 急性膵炎における pancreatic associated protein 臨床的意義の検討
2001 - 2003 , 自己免疫性膵炎患者でのIgG4型自己抗体が認識する自己抗原の解析

科学研究費補助金(研究代表者)
2015 - 2017 , 自己免疫性膵炎、IgG4関連疾患と悪性腫瘍に関する臨床的・免疫遺伝学的検討 , 基盤研究(C)
2011 - 2013 , 自己免疫性膵炎関連遺伝子の全ゲノム関連解析 , 基盤研究(C)
2008 - 2010 , 自己免疫性膵炎発症におけるカリウムイオンチャンネル蛋白Kv1.3関与の検討 , 基盤研究(C)
2004 - 2006 , 自己免疫性膵炎の病態の解明と特異的診断法の確立
2004 - 2005 , 自己免疫性膵炎(IgG4関連膵炎)感受性遺伝子のゲノムワイド検索と構造解析 , 基盤研究(B)
2003 - 2004 , 自己免疫性膵炎(IgG4関連膵炎)感受性遺伝子の検索 , 萌芽研究
2001 - 2003 , 自己免疫性膵炎発症に関連する IgG4 型抗体の認識する自己抗原の検索、ならびに特異的診断システムの開発 , ヒューマンサイエンス振興財団
2000 - 2001 , 膵癌細胞におけるビタミンD, TGFβシグナル伝達系クロストークの検討 , 基盤研究 C
1999 - 2001 , 自己免疫性膵炎発症に関わる自己抗原の解明 , 萌芽的的研究
1996 - 1997 , 各種レチノイドの膵癌細胞株に対する増殖抑制効果、分化誘導効果の検討 , 基盤研究C
1995 - 1996 , ビタミン D 誘導体 (OCT) の膵癌細胞株に対する分化誘導効果の検討 , 一般研究 C
1995 - 1996 , 腫瘍抑制遺伝子 p21, p27 誘導を介する新しい膵癌治療法の開発 , 基盤研究 C
1988 - 1989 , カクテルアッセイ法による膵癌血清診断システムの確立 , 奨励研究 A
1987 - 1988 , 膵癌特異的糖鎖抗原の抽出 , 奨励研究 A
1986 - 1987 , 胎児膵抗原に対するモノクローナル抗体作製のためのスクリーニングシステムの開発 , 奨励研究 A

科学研究費補助金(研究分担者)
2015 - 2016 , 平成27年度厚生労働科学研究費補助金,『IgG4関連疾患の診断基準並びに治療指針の確立を目指した研究』班
2014 - 2016 , 究委託費 難治性疾患等実用化研究事業 「IgG4関連疾患の病因病態解明と新規治療法確立に関する研究」
2014 - 2015 , 厚生労働省科学研究費補助金、難治性疾患克服研究事業、IgG4関連疾患に関する調査研究
2012 - 2013 , 厚生労働省科学研究費補助金、難治性疾患克服研究事業、IgG4関連疾患に関する調査研究
2011 - 2013 , 厚生労働省科学研究費補助金、難治性疾患克服研究事業、難治性膵疾患に関する調査研究
2009 - 2011 , 厚生労働省科学研究費補助金、難治性疾患克服研究事業、新規疾患IgG4関連多臓器リンパ増殖性疾患(IgG4+MOLPS)の確立のための研究
2009 - 2011 , 厚生労働省科学研究費補助金、難治性疾患克服研究事業、IgG4関連効果性疾患の診断法の開発に関する研究
2008 - 2010 , 厚生労働省科学研究費補助金、難治性疾患克服研究事業、難治性膵疾患に関する調査研究
2005 - 2007 , 厚生労働省科学研究費補助金、難治性疾患克服研究事業、難治性膵疾患に関する調査研究
2002 - 2004 , 厚生労働省科学研究費補助金、難治性疾患克服研究事業、難治性膵疾患に関する調査研究

受託事業
ビタミンD 誘導体の生理活性評価に関する研究
PPARγ ligand, troglitazone の膵癌細胞に対する増殖抑制効果の検討
2003 - 2004 , NIK-333 の膵癌増殖抑制に対する作用機序の解明
1998 - 2000 , 腫瘍抑制遺伝子 p21, p27 誘導効果の高いビタミンD 誘導体の開発

その他公的資金
腫瘍マーカーによる集団検診と複数の糖鎖抗原を表現するムチン性抗原を用いた新しい膵癌の血清診断法の確立

教育活動実績

授業等
2002 , 消化器病学
2002 , 膵臓病学