A Novel Splice Site Mutation of Myosin VI in Mice Leads to Stereociliary Fusion Caused by Disruption of Actin Networks in the Apical Region of Inner Ear Hair Cells PLoS One,12(8):e0183477 2017(Aug. 23) Author:Yuta Seki1, Yuki Miyasaka, Sari Suzuki, Kenta Wada, Shumpei P. Yasuda, Kunie Matsuoka, Yasuhiro Ohshiba, Kentaro Endo, Rie Ishii, Hiroshi Shitara, Shin-ichiro Kitajiri, Naomi Nakagata, Hirohide Takebayashi, Yoshiaki Kikkawa
Microarray analyses of otospheres derived from the cochlea in the inner ear identify putative transcription factors that regulate the characteristics of otospheres. PLoS One,12(6):e0179901 2017(Jun.) Author:Iki T, Tanaka M, Kitajiri SI, Kita T, Kawasaki Y, Mizukoshi A, Fujibuchi W, Nakagawa T, Nakahata T, Ito J, Omori K, Saito MK.
Constitutive activation of DIA1 (DIAPH1) via C-terminal truncation causes human sensorineural hearing loss. EMBO Mol Med,8(11):1310-1324 2016(Nov.) Author:Ueyama T, Ninoyu Y, Nishio SY, Miyoshi T, Torii H, Nishimura K, Sugahara K, Sakata H, Thumkeo D, Sakaguchi H, Watanabe N, Usami SI, Saito N, Kitajiri SI.
Tricellular Tight Junctions in the Inner Ear BioMed research international,2016:6137541 2016 Author:Kitajiri S, Katsuno T
Carrier frequency of the GJB2 mutations that cause hereditary hearing loss in the Japanese population Journal of human genetics,60(10):613-617 2015(Oct.) Author:Taniguchi M, Matsuo H, Shimizu S, Nakayama A, Suzuki K, Hamajima N, Shinomiya N, Nishio S, Kosugi S, Usami S, Ito J, Kitajiri S
Limited hair cell induction from human induced pluripotent stem cells using a simple stepwise method Neuroscience letters,599:49-54 2015(Jul.) Author:Ohnishi H, Skerleva D, Kitajiri S, Sakamoto T, Yamamoto N, Ito J, Nakagawa T
Detailed hearing and vestibular profiles in the patients with COCH mutations The Annals of otology, rhinology, and laryngology,124 Suppl 1:100S-10S 2015(May) Author:Tsukada K, Ichinose A, Miyagawa M, Mori K, Hattori M, Nishio SY, Naito Y, Kitajiri S, Usami S
Mutational spectrum and clinical features of patients with ACTG1 mutations identified by massively parallel DNA sequencing The Annals of otology, rhinology, and laryngology,124 Suppl 1:84S-93S 2015(May) Author:Miyagawa M, Nishio SY, Ichinose A, Iwasaki S, Murata T, Kitajiri S, Usami S
The actin-bundling protein TRIOBP-4 and -5 promotes the motility of pancreatic cancer cells Cancer letters,356(2 Pt B):367-373 2015(Jan.) Author:Bao J, Wang S, Gunther LK, Kitajiri S, Li C, Sakamoto T
Downsloping high-frequency hearing loss due to inner ear tricellular tight junction disruption by a novel ILDR1 mutation in the Ig-like domain PloS one,10(2):e0116931 2015 Author:Kim NK, Higashi T, Lee KY, Kim AR, Kitajiri S, Kim MY, Chang MY, Kim V, Oh SH, Kim D, Furuse M, Park WY, Choi BY
Deficiency of angulin-2/ILDR1, a tricellular tight junction-associated membrane protein, causes deafness with cochlear hair cell degeneration in mice PloS one,10(3):e0120674 2015 Author:Higashi T, Katsuno T, Kitajiri S, Furuse M
Deafness in occludin-deficient mice with dislocation of tricellulin and progressive apoptosis of the hair cells Biology open,3(8):759-766 2014(Jul.) Author:Kitajiri S, Katsuno T, Sasaki H, Ito J, Furuse M, Tsukita S
Caprice/MISP is a novel F-actin bundling protein critical for actin-based cytoskeletal reorganizations Genes to cells : devoted to molecular & cellular mechanisms,19(4):338-349 2014(Apr.) Author:Kumeta M, Gilmore JL, Umeshima H, Ishikawa M, Kitajiri S, Horigome T, Kengaku M, Takeyasu K
In vivo imaging of mouse cochlea by optical coherence tomography Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology,35(2):e84-9 2014(Feb.) Author:Tona Y, Sakamoto T, Nakagawa T, Adachi T, Taniguchi M, Torii H, Hamaguchi K, Kitajiri S, Ito J
Ethnic differences in ATP-binding cassette transporter, sub-family G, member 2 (ABCG2/BCRP): genotype combinations and estimated functions Drug metabolism and pharmacokinetics,29(6):490-492 2014 Author:Sakiyama M, Matsuo H, Takada Y, Nakamura T, Nakayama A, Takada T, Kitajiri S, Wakai K, Suzuki H, Shinomiya N
R1 motif is the major actin-binding domain of TRIOBP-4 Biochemistry,52(31):5256-5264 2013(Aug.) Author:Bao J, Bielski E, Bachhawat A, Taha D, Gunther LK, Thirumurugan K, Kitajiri S, Sakamoto T
Analysis of the 'angulin' proteins LSR, ILDR1 and ILDR2--tricellulin recruitment, epithelial barrier function and implication in deafness pathogenesis Journal of cell science,126(Pt 4):966-977 2013(Feb.) Author:Higashi T, Tokuda S, Kitajiri S, Masuda S, Nakamura H, Oda Y, Furuse M
Adipose tissue-derived stromal cells protect hair cells from aminoglycoside The Laryngoscope,121(6):1281-1286 2011(Jun.) Author:Yoshida A, Kitajiri S, Nakagawa T, Hashido K, Inaoka T, Ito J
Insulin-like growth factor 1 protects vestibular hair cells from aminoglycosides Neuroreport,22(1):38-43 2011(Jan.) Author:Angunsri N, Taura A, Nakagawa T, Hayashi Y, Kitajiri S, Omi E, Ishikawa K, Ito J
Actin-bundling protein TRIOBP forms resilient rootlets of hair cell stereocilia essential for hearing Cell,141(5):786-798 2010(May) Author:Kitajiri S, Sakamoto T, Belyantseva IA, Goodyear RJ, Stepanyan R, Fujiwara I, Bird JE, Riazuddin S, Riazuddin S, Ahmed ZM, Hinshaw JE, Sellers J, Bartles JR, Hammer JA 3rd, Richardson GP, Griffith AJ, Frolenkov GI, Friedman TB
Identities, frequencies, and origins of TMC1 mutations causing DFNB7/B11 deafness in Pakistan Clin Genet,72(6):546-550 2007 Author:Kitajiri SI, McNamara R, Makishima T, Husnain T, Zafar AU, Kittles RA, Ahmed ZM, Friedman TB, Riazuddin S, Griffith AJ
A novel mutation at the DFNA36 hearing loss locus reveals a critical function and potential genotype-phenotype correlation for amino acid-572 of TMC1 Clin Genet,71(2):148-152 2007 Author:Kitajiri S, Makishima T, Friedman TB, Griffith AJ
Mutations of the RDX gene cause nonsyndromic hearing loss at the DFNB24 locus Hum Mutat,28(5):417-423 2007 Author:Khan SY, Ahmed ZM, Shabbir MI, Kitajiri S, Kalsoom S, Tasneem S, Shayiq S, Ramesh A, Srisailpathy S, Khan SN, Smith RJ, Riazuddin S, Friedman TB, Riazuddin S
Tricellulin is a tight-junction protein necessary for hearing Am J Hum Genet,79(6):1040-1051 2006 Author:Riazuddin S, Ahmed ZM, Fanning AS, Lagziel A, Kitajiri S, Ramzan K, Khan SN, Chattaraj P, Friedman PL, Anderson JM, Belyantseva IA, Forge A, Riazuddin S, Friedman TB
Disruption and restoration of cell?cell junctions in mouse vestibular epithelia following aminoglycoside treatment Hear Res,205( 1-2):201-209 2005 Author:Kim TS, Nakagawa T, Kitajiri S, Endo T, Takebayashi S, Iguchi F, Kita T, Tamura T, Ito J
Genes related to hearing disorders Acta Otolaryngologica,Suppl. 551:10-13 2004 Author:Kitajiri S, Sakamoto T, Ito J
Expression patterns of claudins, tight junction adhesion molecules, in the inner ear Hear Res,187( 1-2):25-34 2004 Author:Kitajiri SI, Furuse M, Morita K, Saishin-Kiuchi Y, Kido H, Ito J, Tsukita S
Radixin deficiency causes deafness associated with progressive degeneration of cochlear stereocilia Journal of Cell Biology,166(4):559-570 2004 Author:Kitajiri S, Fukumoto K, Hata M, Sasaki H, Katsuno T, Nakagawa T, Ito J, Tsukita S, Tsukita S
Compartmentalization established by claudin-11-based tight junctions in stria vascularis is required for hearing through generation of endocochlear potential Journal of Cell Science,117(Pt 21):5087-5096 2004 Author:Kitajiri S, Miyamoto T, Mineharu A, Sonoda N, Furuse K, Hata M, Sasaki H, Mori Y, Kubota T, Ito J, Furuse M, Tsukita S
The presence of large lymph node metastasis as a prognostic factor of papillary thyroid carcinoma Auris Nasus Larynx,30(2):169-174 2003 Author:Kitajiri S, Hiraumi H, Hirose T, Hosaka N
Increased expression of integrin beta-4 in papillary thyroid carcinoma with gross lymph node metastasis Pathology international,52(7):438-441 2002(Jul.) Author:Kitajiri S, Hosaka N, Hiraumi H, Hirose T, Ikehara S
Is Corticosteroid Therapy Effective for Sudden-Onset Sensorineural Hearing Loss at Lower Frequencies? Arch Otolaryngol Head Neck Surg,128(4):365-367 2002 Author:Kitajiri S, Tabuchi K, Hiraumi H, Hirose T
Ectopic pituitary adenoma with malignant transformation American Journal of Surgical Pathology,26(8):1078-1082 2002 Author:Hosaka N, Kitajiri S, Hiraumi H, Nogaki H, Toki J, Yang G, Hisha H, Ikehara S
Radiosensitive hemangiopericytoma in the soft palate Auris Nasus Larynx,9(1):95-97 2002 Author:Hiraumi H, Kitajiri S, Hirose T, Hosaka N, Toki J, Ikehara S
Dermal thymus: case report and review of the literature American journal of otolaryngology,22(4):294-296 2001(Jul.) Author:Hiraumi H, Tabuchi K, Kitajiri S
Relief of Post-tonsillectomy Pain by Release of Lidocaine from Fibrin Glue Laryngoscope,111(5):642-644 2001 Author:Kitajiri S, Tabuchi K, Hiraumi H, Kaetsu H
Transnasal Bamboo Foreign Body Lodged in the Sphenoid Sinus Auris Nasus Larynx,28(4):365-367 2001 Author:Kitajiri S, Tabuchi K, Hiraumi H
A Case Report of FSH-Producing Nasal Ectopic Pituitary Adenoma Extending to the Frontal Cranial Fossa Arch Otolaryngol Head Neck Surg,126(6):782-784 2000 Author:Kitajiri S, Hosaka N, Tabuchi K, Hiraumi H, Nogaki H, Tatsumi S, Toki J, Ikehara S
Regulation of the localization of molecules in hair cell stereocilia by TRIOBP ARO The 41st Annual MidWinter Meeting 2018(Feb. 09) Presenter:Tomoko Kita, Raj K Ladher, Shin-ichi Usami, Shin-ichiro Kitajiri
Making tool for analysis of TRIOBP function using induced pluripotent stem cell ARO The 41st Annual MidWinter Meeting 2018(Feb. 09) Presenter:Hiroe Ohnishi、Shin-ichiro Kitajiri、Xiangxin Lou、Akiko Taura、Mirei Taniguchi、Fumi Ebisu、Tatsunori Sakamoto、Norio Yamamoto、Juichi Ito1、Koichi Omori、Takayuki Nakagawa
An Attempt to Establish In Vitro Model Using TRIOBP KO Induced Pluripotent Stem Cells International Symposium on Inner Ear Therapies 2017(Nov. 01) Presenter:Hiroe Ohnishi、Shin-ichiro Kitajiri、Xiangxin Lou、Akiko Taura、Mirei Taniguchi、Fumi Ebisu、Tatsunori Sakamoto、Norio Yamamoto、Juichi Ito1、Koichi Omori、Takayuki Nakagawa
The development and maintenance of hair cell stereocilia rootlets by isoform specific functions of TRIOBP 54th workshop on Inner Ear Biology and Symposium 2017(Sep. 13) Presenter:Tatsuya Katsuno, Inna A. Belyantseva, Ronald S. Petralia, Ya-Xian Wang, Keisuke Ohta, Kazuya Ono, Makoto Ikeya, Gavin P. Riordan, Joseph Duda, Elizabeth Wilson, Tracy Fitzgerald, Atteeq U. Rehman, Ayesha Imtiaz, Juichi Ito, Thomas B. Friedman, Shin-ichiro Kitajiri
Abnormal actin elongation activity of a novel hearing-loss Dia1 mutant revealed by single-molecule speckle microscopy 54th workshop on Inner Ear Biology and Symposium 2017(Sep. 13) Presenter:Takushi Miyoshi, Yuzuru Ninoyu, Naoki Watanabe, Shin-ichiro Kitajiri, and Takehiko Ueyama
The functional analysis of DIAPH1, the responsible gene for DFNA1 International Congress of ORL-HNS 2017(Apr. 21) Presenter:Shin-ichiro KITAJIRI
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