論文 Theobromine enhances the conversion of white adipocytes into beige adipocytes in a PPARγ activation-dependent manner J. Nutritional Biochem,100:108898 2022 Author:E. Tanaka, T. Mitani, M. Nakashima, E. Yonemoto, H. Fujii, and H. Ashida Keywords:Autophagy; Browning; Beige adipocyte; Theobromine; Peroxisome proliferator-activated receptor gamma;
Copper-Free Huisgen Cycloaddition for the 14-3-3-Templated Synthesis of Fusicoccin-Peptide Conjugates Chemistry : an Asian journal,15(6):742-747 2020(Feb.) Author:R. Masuda, Y. Kawasaki K. Igawa, Y. Manabe, H. Fujii, N. Kato K. Tomooka and *J. Ohkanda
Intracellular cAMP contents regulate NAMPT expression via induction of C/EBPβ in adipocytes Biochemical and Biophysical Research Communications,522(3):770-775 2020(Feb.) Author:*T. Mitani, S. Watanabe, K. Wada, H. Fujii, S. Nakamura, and S. Katayama
Identification and characterization of oligomeric proanthocyanidins with significant anti-cancer activity in adzuki beans (Vigna angularis) Heliyon,5:e02610 2019(Oct.) Author:S. Kawahara, C. Ishihara, K. Matsumoto, S. Senga, K, Kawaguchi, A.Yamamoto, J. Suwannachot, Y. Hamauzu, H. Makabe, and *H. Fujii
Fermented rice peptides attenuate scopolamine-induced memory impairment in mice by regulating neurotrophic signaling pathways in the hippocampus. Brain Research,1720:146322 2019(Oct.) Author:H. M. Corpuz, H. Fujii, S. Nakamura, and S. Katayama
A Guanidyl-Based Bivalent Peptidomimetic Inhibits K-Ras Prenylation and Association with c-Raf Chemistry A European J.,25(59):13531-13536 2019(Oct.) Author:M. Tsubamoto, T. K. Le, T. Watabnabe, C. Matsumi, P. Parvatkar, H. Fujii, J.Sun N. Kato, and *J. Ohkanda
Isolation and characterization of a novel oligomeric proanthocyanidin with significant anti-cancer activities from grape stems (Vitis vinifera). Sci. Rep.,9:12046 2019(Aug.) Author:S. Kawahara, K. Toda, K. Matsumoto, C. Ishihara, S. Nonobe, C. Matsunaga, Y. K. Gomi, S. Senga, K, Kawaguchi, A.Yamamoto, J. Suwannachot, R., Noda, S. Kobayashi, Y. Hamauzu, H. Makabe, and *H. Fujii
Adzuki bean (Vigna angularis) extract reduces amyloid beta aggregation and corrects cognitive impairment in Drosophila models of Alzheimer's disease. Nutrition Research and Practice,13(1):64-69 2019(Feb.) Author:H. Miyazaki, Y. Okamoto, T. Watanabe, S. Katayama, S. Kawahara, H. Makabe, H. Fujii, S. Yonekura
Evidence for the involvement of FXR signaling in ovarian granulosa cell function. J. Reprod. Dev.,65(1):47-55 2019(Feb.) Author:K. Takae, M. Nakata, T. Watanabe, H. Sasada, H. Fujii, and I. Tomioka
A novel Fatty acid-binding protein 5-Estrogen-related receptor α signaling pathway promotes cell growth and energy metabolism in prostate cancer cells. Estrogen-related receptor α signaling pathway promotes cell growth and energy metabolism in prostate cancer cells. Oncotarget,9(60):31753-31770 2018(Aug. 03) Author:S. Senga, K. Kawaguchi, N. Kobayashi, A. Ando and H. Fujii Keywords:FABP5, ERRa, PGC-1b, energy metabolism, prostate cancer
Soybean-Derived Glycine-Arginine Dipeptide Administration Promotes Neurotrophic Factor Expression in the Mouse Brain Journal of Agricultural and Food Chemistry,66(30):7935-7941 2018(Aug.) Author:A. Shimizu, T. Mitani, S. Tanaka, H. Fujii, M. Maebuchi, Y. Amiya, M. Tanaka, T. Matsui, S. Nakamura, *S. Katayama
Fatty acid-binding protein 5 (FABP5) promotes lipolysis of lipid droplets, de novo fatty acid (FA) and activation of nuclear factor-kappa B (NF-kB) signaling in cancer cells. BBA-Molecular and Cellular Biology of Lipids,1863(9):1057-1067 2018(Jun. 12) Author:S. Senga, N. Kobayashi, K. Kawaguchi, A. Ando and H. Fujii Keywords:FABP5, lipolysis, lipid droplet, fatty acid metabolism, cancer, inflammation
Synthesis of epigallocatechin trimer, (epigallocatechin)2-epicatechin, and (epigallocatechin)2-catechin via a Lewis acid mediated one-pot condensation and their antitumor activities in prostate cancer cells. Tetrahedron,74:3534-3542 2018(May 17) Author:M. Ichikawa, S. Yamamoto, C. Ishihara, S. Nonobe, Y. Hattori, K. Umezawa, H. Fujii, and H. Makabe Keywords:plyphenol, condensation, Lewis acid, proanthocyanidin, antitumor
Adzuki Bean (Vigna angularis) Extract Inhibits 3T3-L1 Preadipocyte Differentiation Journal of Food and Nutrition Research,5(12):908-913 2017(Nov.) Author:*S. Yonekura, Y. Obayashi, Y. Tokutake, S. Kawahara, H. Makbe and H. Fujii
Epicatechin oligomers longer than trimers have anti-cancer activities, but not the catechin counterparts. Sci. Rep.,7:7791 2017(Aug. 10) Author:K. Takanashi, M. Suda, K. Mastumoto, C. Ishihara, K. Toda, K. Kawaguchi, S. Senga, N. kobayashi, M. Katoh, Y. Hattori, S. Kawahara, *H. Fujii, and *H. Makabe
Synthesis of Prodelphinidin Trimer isolated from Cistus albidus and its antitumor activity against human prostate cancer cell lines Heterocycle,92(10):1822-1831 2016(Oct.) Author:M. Mori, K. Matsumoto, C. Ishihara, K. Kawaguchi S. Kawahara, Y. Hattori,e H. Fujii, and H. Makabe
Identification of multiple forms of RNA transcripts associated with human-specific retrotransposed gene copies. Genome Biology and Evolution 2016(Jul.) Author:. Mori, M. Hayashi, S. Inagaki, T. Ohhima, K. Tateishi, H. Fujii and S. Suzuki
Concise Synthesis of Cinnamtannin A2 from Dimeric Epicatechin Electrophile and Nucleophile Prepared by Zn(OTf)2 Mediated Self-Condensation Synthesis,48:1525-1532 2016(Feb. 25) Author:M. Ichikawa, K. Takanashi, M. Suda, Y. Hattori, S. Kawahara, H. Fujii, H. Makabe
High expression of Fatty Acid-Binding Protein 5 promotes cell growth and metastatic potential of colorectal cancer cells FEBS OpenBio,6:190-199 2016(Feb.) Author:Koichiro Kawaguchi, Shogo Senga, Chiaki Kubota, Yuki Kawamura, Youqiang Ke and Hiroshi Fujii Keywords:FABP5, growth Promotion, metastasis, colorectal cancer
The Cancer-Promoting Gene Fatty Acid-Binding Protein 5 (FABP5) is Epigenetically Regulated During Human Prostate Carcinogenesis Biochemical Journal,473:449-461 2016(Feb.) Author:Koichiro Kawaguchi, Ayumi Kinameri, Shunsuke Suzuki, Shogo Senga, Youqiang Ke, Hiroshi Fujii
Synthesis of Arecatannin A1 from dimeric epichatechin electrophile Natural Product Communications,10(6):959-962 2015 Author:M. Suda, K. Takanashi, M. Katoh, et al.
Syntheses of prodelphinidin B1, B2, and B4 and their antitumor activities against human PC-3 prostate cancer cell lines TETRAHEDRON LETTERS,54(52):7188-7192 2013(Dec.) Author:Fujii, W; Toda, K; Matsumoto, K; Kawaguchi, K; Kawahara, S; Hattori, Y; Fujii, H; Makabe, H
Syntheses of procyanidin B2 and B3 gallate derivatives using equimolar condensation mediated by Yb(OTf)(3) and their antitumor activities BIOORGANIC&MEDICINAL CHEMISTRY LETTERS,23(17):4935-4939 2013(Sep.) Author:Suda, M; Katoh, M; Toda, K; Matsumoto, K; Kawaguchi, K; Kawahara, S; Hattori, Y; Fujii, H; Makabe, H
Syntheses of prodelphinidin B3 and C2, and their antitumor activities through cell cycle arrest and caspase-3 activation TETRAHEDRON,69(17):3543-3550 2013(Apr.) Author:Fujii, W; Toda, K; Kawaguchi, K; Kawahara, S; Katoh, M; Hattori, Y; Fujii, H; Makabe, H
Synthesis of procyanidin C2&C1 using Lewis acid mediated equimolar condensation. Heterocycles,85(9):2241-2250 2012 Author:Y. Oizumi, M. Katoh, Y. Hattori, K. Toda, K. Kawaguchi, H. Fujii, and H. Makabe
Diagnosis of ischemic small bowel disease by measurement of serum intestinal fatty acid-binding protein in patients with acute abdomen: a multicenter, observer-blinded validation study. J. Gastroenterology,46:492-500 2011 Author:T Kanda, T. Tsukada, K. Ueki, Y. Sakai, T. Tani, J. Nishimura, T. Yamazaki, Y. Tamiya, T. Tada, M. Hirota, J. Hasegawa, H. Funaoka, H. Fujii and K. Hatakeyama
Effects of light wavelength and intensity on the expression of photoresponse genes in oyster mushroom mycelia. J. Light&Visual Environment,35 2011 Author:Y. Nakano, H. Fujii, M. Kojima
Development of a high-specificity sandwich ELISA system for the quantificaion of human intestinal fatty acid-binding protein (I-FABP) concentrations. Immunological Investigation.,40(1):1-20 2010 Author:H. Funaoka, T. Kanda, S. Kajiura, Y. Ohkaru et al.
Identification of blue-light photoresponse genes in oyster mushroom mycelia. Biosci. Biotechnol. Biochem.,74:2160-2165 2010 Author:Y. Nakano, H.Fujii, M. Kojima
Light stimulation triggered expressionof gene coding for vacuolar proton-pump enzymes v-ATPase and v-PPase in buckwheat. Biosci. Biotechnol. Biochem.,74(7):1507-1511 2010 Author:M. Kojima, Y. Nakano, H. Fujii
Loss of enterocyte mass is accompanied by diminished turn over of enterocytes after myeloablative therapy in haematopoietic stem cell transplant recipients. Ann. Oncol.,20(2):337-342 2009 Author:J. Derikx, N. Blijlevens, H. Fujii, T. Kanda
A natural PPAR-g agonist, 15-deoxy-delta 12, 14-prostaglandin J2, may act as an enhancer of PAI-1 in human proximal renal tubular cells under hypoxic and inflammatory conditions. Nephrol. Dial. Transplant,23(8):2496-3503 2008 Author:H. Kimura, L. Xuan, K. Torii, T. Okada
A novel method for RNA interference in neurons using enhanced green fluorescent protein (EGFP)-transgenic rat. Neurosci. Res.,61(2):219-224 2008 Author:L. Jia, M. Nozumi, H. Fujii and M. Igarashi
Expression of Cutaneous fatty acid-binding protein (C-FABP) in prostate cancer: Potential prognostic marker and target for tumougigenicity-suppression Int. J. Oncol.,32:767-775 2008 Author:E. A. Morgan, S. S. Forootan, J. Adamson, C. S. Foster
Establishment and characterization of monoclonal and polyclonal antibodies against human intestinal fatty acid-binding protein (I-FABP). J. Immunoassay&Immunochem.,29:19-41 2008 Author:S. Kajiura, T. Yashiki, H. Funaoka, Y. Ohkaru,
Hypoxia reduces expression of peroxisome proliferators-activated receptor-g and its anti-inflammatory effects in human proximal renal tubular cells. Nephrol. Dial. Transplant,22:1041-1051 2007 Author:X. Li, H. Kimura, K. Hirota, H. Sugimoto, H. Fujii
LXR alpha transactivates mouse organic solute transporter alpha and beta via IR-1 elements shared with FXR. Pharmaceutical Res.,24(2):390-398 2007 Author:M. Okuwaki, T. Takada, Y. Iwayanagi, S. Koh
Fatty acid-binding protein 6, FABP 6, is overexpressed in colorectal cancer. Clin. Cancer Res.,12(17):5090-5095 2006 Author:T. Ohmachi, H. Inoue, K. Mimori, F. Tanaka et al