信州大学HOMEENGLISH交通・キャンパス案内

研究者総覧研究者総覧

研究者、研究内容などで検索
項目別検索はこちら

城下智  ジョウシタ サトル

教員組織学術研究院(医学系)電話番号
教育組織医学部 医学科 内科学第二FAX番号
職名助教メールアドレス
住所〒390-8621 長野県松本市旭3-1-1ホームページURLhttp://www.shinshu-u.ac.jp/faculty/medicine/chair/i-2nai/

プロフィール

兼担研究科・学部
信州大学次世代医療研究センター
研究分野
内科学
消化器内科学
学歴
出身学校・専攻等(大学院を除く)
2002 , 新潟大学医学部

免許・資格等
2015年11月 , Fellow of American Collage of Physician
2011年4月 , 日本人間ドック学会認定医
2010年4月 , 日本肝臓学会肝臓専門医
2010年12月 , 日本消化器内視鏡学会専門
2010年10月 , 日本超音波医学会超音波専門医
2009年1月 , 日本消化器病学会消化器病専門医
2008年4月 , 日本がん治療認定医機構がん治療認定医
2008年12月 , 日本内科学会総合内科専門医
2005年7月 , 厚生労働省臨床研修指導医
2003年1月 , 日本医師会認定産業医
2002年9月 , 日本医師会認定健康スポーツ医

研究活動業績

研究業績(著書・
発表論文等)
論文
Association between lower air pressure and the onset of ischemic colitis: a case-control study
EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY,29(9):1071-1078 2017(Sep.)
Author:Kimura, Takefumi; Shinji, Akihiro; Tanaka, Naoki; Koinuma, Masayoshi; Yamaura, Maki; Nagaya, Tadanobu; Joshita, Satoru; Komatsu, Michiharu; Umemura, Takeji; Horiuchi, Akira; Wada, Shuichi; Tanaka, Eiji;


Association between serum soluble CD14 and IL-8 levels and clinical outcome in primary biliary cholangitis
LIVER INTERNATIONAL,37(6):897-905 2017(Jun.)
Author:Umemura, Takeji; Sekiguchi, Tomohiro; Joshita, Satoru; Yamazaki, Tomoo; Shibata, Soichiro; Ichikawa, Yuki; Komatsu, Michiharu; Matsumoto, Akihiro; Shums, Zakera; Norman, Gary L.; Tanaka, Eiji; Ota, Masao;


IL33/ST2 PATHWAY INVOLVEMENT IN THE PATHOGENESIS AND DISEASE PROGRESSION OF PRIMARY BILIARY CHOLANGITIS
GASTROENTEROLOGY,152(5):S1185-S1185 2017(Apr.)
Author:Joshita, Satoru; Umemura, Takeji; Matsumoto, Akihiro; Yoshizawa, Kaname; Ota, Masao; Tanaka, Eiji;


Clinicopathological characteristics of non-B non-C hepatocellular carcinoma without past hepatitis B virus infection
HEPATOLOGY RESEARCH,47(5):405-418 2017(Apr.)
Author:Kimura, Takefumi; Kobayashi, Akira; Tanaka, Naoki; Sano, Kenji; Komatsu, Michiharu; Fujimori, Naoyuki; Yamazaki, Tomoo; Shibata, Soichiro; Ichikawa, Yuki; Joshita, Satoru; Umemura, Takeji; Matsumoto, Akihiro; Horiuchi, Akira; Mori, Hiromitsu; Wada, Shuichi; Kiyosawa, Kendo; Miyagawa, Shin-ichi; Tanaka, Eiji;


Serum Wisteria floribunda agglutinin-positive human Mac-2 binding protein may predict liver fibrosis and progression to hepatocellular carcinoma in patients with chronic hepatitis B virus infection
HEPATOLOGY RESEARCH,47(2):226-233 2017(Feb.)
Author:Ichikawa, Yuki; Joshita, Satoru; Umemura, Takeji; Shobugawa, Yugo; Usami, Yoko; Shibata, Soichiro; Yamazaki, Tomoo; Fujimori, Naoyuki; Komatsu, Michiharu; Matsumoto, Akihiro; Tanaka, Eiji;


Genome-wide association studies identify PRKCB as a novel genetic susceptibility locus for primary biliary cholangitis in the Japanese population.
Hum Mol Genet,in press 2017(Jan.)
Author:Kawashima M, Hitomi Y, Aiba Y, Nishida N, Kojima K, Kawai Y, Nakamura H, Tanaka A, Zeniya M, Hashimoto E, Ohira H, Yamamoto K, Abe M, Nakao K, Yamagiwa S, Kaneko S, Honda M, Umemura T, Ichida T, Seike M, Sakisaka S, Harada M, et al.


Genetic Contribution to the Pathogenesis of Primary Biliary Cholangitis
JOURNAL OF IMMUNOLOGY RESEARCH,:- 2017
Author:Joshita, Satoru; Umemura, Takeji; Tanaka, Eiji; Ota, Masao;


Association between endotoxemia and histological features of nonalcoholic fatty liver disease
WORLD JOURNAL OF GASTROENTEROLOGY,23(4):712-722 2017
Author:Kitabatake, Hiroyuki; Tanaka, Naoki; Fujimori, Naoyuki; Komatsu, Michiharu; Okubo, Ayaka; Kakegawa, Kyogo; Kimura, Takefumi; Sugiura, Ayumi; Yamazaki, Tomoo; Shibata, Soichiro; Ichikawa, Yuki; Joshita, Satoru; Umemura, Takeji; Matsumoto, Akihiro; Koinuma, Masayoshi; Sano, Kenji; Aoyama, Toshifumi; Tanaka, Eiji;


Association between serum soluble CD14 and IL-8 levels and clinical outcome in primary biliary cholangitis.
Liver Int,in press 2016(Nov.)
Author:Umemura T, Sekiguchi T, Joshita S, Yamazaki T, Fujimori N, Shibata S, Ichikawa Y, Komatsu M, Matsumoto A, Shums Z, Norman GL, Tanaka E, Ota M.


Liver stiffness-spleen size-to-platelet ratio risk score identifies esophageal varices in Japanese patients with chronic hepatitis C.
Hepatol Res,46(9):884-9 2016(Aug.)
Author:Shibata S, Umemura T, Yamazaki T, Fujimori N, Ichikawa Y, Kimura T, Joshita S, Komatsu M, Matsumoto A, Tanaka E.


Incidence and prevalence of autoimmune hepatitis in the Ueda area, Japan.
Hepatol Res,46(9):878-83 2016(Aug.)
Author:Yoshizawa K, Joshita S, Matsumoto A, Umemura T, Tanaka E, Morita S, Maejima T, Ota M.


Genetic Association of PTPN22 Polymorphisms with Autoimmune Hepatitis and Primary Biliary Cholangitis in Japan.
Sci Rep,6:29770 2016(Jul.)
Author:Umemura T, Joshita S, Yamazaki T, Komatsu M, Katsuyama Y, Yoshizawa K, Tanaka E, Ota M.


Liver stiffness-spleen size-to-platelet ratio risk score detects esophageal varices in chronic liver disease.
Springerplus,5(1):998 2016(Jul.)
Author:Shibata S, Joshita S, Umemura T, Yamazaki T, Fujimori N, Ichikawa Y, Komatsu M, Matsumoto A, Tanaka E.


Clinicopathological characteristics of non-B non-C hepatocellular carcinoma without past hepatitis B virus infection.
Hepatol Res,in press 2016(Jun.)
Author:Kimura T, Kobayashi A, Tanaka N, Sano K, Komatsu M, Fujimori N, Yamazaki T, Shibata S, Ichikawa Y, Joshita S, Umemura T, Matsumoto A, Horiuchi A, Mori H, Wada S, Kiyosawa K, Miyagawa SI, Tanaka E.


Serum Wisteria floribunda agglutinin-positive human Mac-2 binding protein may predict liver fibrosis and progression to hepatocellular carcinoma in patients with chronic hepatitis B virus infection.
Hepatol Res,in press 2016(Mar.)
Author:Ichikawa Y, Joshita S, Umemura T, Shobugawa Y, Usami Y, Shibata S, Yamazaki T, Fujimori N, Komatsu M, Matsumoto A, Tanaka E.


Lymphocyte Antigen 75 Polymorphisms Are Associated with Disease Susceptibility and Phenotype in Japanese Patients with Inflammatory Bowel Disease.
Dis Markers,2016:6485343 2016
Author:Hirayama A, Joshita S, Kitahara K, Mukawa K, Suga T, Umemura T, Tanaka E, Ota M.


Serum Wisteria floribunda Agglutinin-Positive Mac-2-Binding Protein Level Predicts Liver Fibrosis and Prognosis in Primary Biliary Cirrhosis.
Am J Gastroenterol,110(6):857-64 2015(Jun.)
Author:Umemura T, Joshita S, Sekiguchi T, Usami Y, Shibata S, Kimura T, Komatsu M, Matsumoto A, Ota M, Tanaka E.


Serum cell death biomarkers for prediction of liver fibrosis and poor prognosis in primary biliary cirrhosis.
PLoS One,10(6):e0131658 2015(Jun.)
Author:Sekiguchi T, Umemura T, Fujimori N, Shibata S, Ichikawa Y, Kimura T, Joshita S, Komatsu M, Matsumoto A, Tanaka E, Ota M.


Steatogenesis in adult-onset type II citrullinemia is associated with down-regulation of PPARα.
Biochim Biophys Acta,1852(3):473-81 2015(Mar.)
Author:Komatsu M, Kimura T, Yazaki M, Tanaka N, Yang Y, Nakajima T, Horiuchi A, Fang ZZ, Joshita S, Matsumoto A, Umemura T, Tanaka E, Gonzalez FJ, Ikeda S, Aoyama T.


【C型肝炎治療update】 治療 IFNβ+リバビリン併用療法
日本臨床,73(2):273-279 2015(Feb.)
Author:城下智, 田中榮司


STAT4 Gene Polymorphisms Are Associated with Susceptibility and ANA Status in Primary Biliary Cirrhosis
DISEASE MARKERS,2014:727393 2014
Author:Joshita, S; Umemura, T; Nakamura, M; Katsuyama, Y; Shibata, S; Kimura, T; Morita, S; Komatsu, M; Matsumoto, A; Yoshizawa, K; Ishibashi, H; Tanaka, E; Ota, M


Liver Dysfunction and Thrombocytopenia Diagnosed as Intravascular Large B-cell Lymphoma Using a Timely and Accurate Transjugular Liver Biopsy
INTERNAL MEDICINE,52(17):1903-1908 2013
Author:Sekiguchi, N; Joshita, S; Yoshida, T; Kurozumi, M; Sano, K; Nakagawa, M; Ito, T; Matsushita, T; Komatsu, D; Komatsu, M; Ito, T; Umemura, T; Ikeda, S; Kadoya, M; Ishida, F; Tanaka, E


Cutaneous sarcoidosis in a chronic hepatitis C patient receiving pegylated interferon and ribavirin therapy
HEPATOLOGY RESEARCH,43(7):801-807 2013
Author:Joshita, S; Shirahata, K; Yazaki, Y; Okaniwa, S; Nakamura, Y; Kimura, T; Noami, S; Horigome, R; Yagi, H; Ito, N; Yamazaki, A; Akahane, Y; Umemura, T; Yoshizawa, K; Tanaka, E; Ota, M


Super high resolution for single molecule-sequence-based typing of classical HLA loci at the 8-digit level using next generation sequencers
Tissue Antigens,80(4):305-316 2012(Oct.)
Author:Shiina T, Suzuki S, Ozaki Y, Taira H, Kikkawa E, Shigenari A, Oka A, Umemura T, Joshita S, Takahashi O, Hayashi Y, Paumen M, Katsuyama Y, Mitsunaga S, Ota M, Kulski JK, Inoko H


Genome-wide association study identifies TNFSF15 and POU2AF1 as susceptibility loci for primary biliary cirrhosis in the Japanese population
Am J Hum Genet,91(4):721-728 2012(Oct.)
Author:Nakamura M, Nishida N, Kawashima M, Aiba Y, Tanaka A, Yasunami M, Nakamura H, Komori A, Nakamuta M, Zeniya M, Hashimoto E, Ohira H, Yamamoto K, Onji M, Kaneko S, Honda M, Yamagiwa S, Nakao K, Ichida T, Takikawa H, Seike M, Umemura T, Ueno Y, Sakisaka S, Kikuchi K, Ebinuma H, Yamashiki N, Tamura S, Sugawara Y, Mori A, Yagi S, Shirabe K, Taketomi A, Arai K, Monoe K, Ichikawa T, Taniai M, Miyake Y, Kumagi T, Abe M, Yoshizawa K, Joshita S, Shimoda S, Honda K, Takahashi H, Hirano K, Takeyama Y, Harada K, Migita K, Ito M, Yatsuhashi H, Fukushima N, Ota H, Komatsu T, Saoshiro T, Ishida J, Kouno H, Kouno H, Yagura M, Kobayashi M, Muro T, Masaki N, Hirata K, Watanabe Y, Nakamura Y, Shimada M, Hirashima N, Komeda T, Sugi K, Koga M, Ario K, Takesaki E, Maehara Y, Uemoto S, Kokudo N, Tsubouchi H, Mizokami M, Nakanuma Y, Tokunaga K, Ishibashi H


Changes in the serum level of hepatitis B virus (HBV) surface antigen over the natural course of HBV infection
J Gastroenterol,47(9):1006-1013 2012(Sep.)
Author:Matsumoto A, Tanaka E, Morita S, Yoshizawa K, Umemura T, Joshita S


Long-term outcome of Japanese patients with type 1 autoimmune hepatitis
Hepatology,56(2):668-676 2012(Aug.)
Author:Yoshizawa K, Matsumoto A, Ichijo T, Umemura T, Joshita S, Komatsu M, Tanaka N, Tanaka E, Ota M, Katsuyama Y, Kiyosawa K, Abe M, Onji M


Association of IL28B gene polymorphism with development of hepatocellular carcinoma in Japanese patients with chronic hepatitis C virus infection
HUMAN IMMUNOLOGY,73(3):298-300 2012(Mar.)
Author:Joshita, Satoru; Umemura, Takeji; Katsuyama, Yoshihiko; Ichikawa, Yuki; Kimura, Takefumi; Morita, Susumu; Kamijo, Atsushi; Komatsu, Michiharu; Ichijo, Tetsuya; Matsumoto, Akihiro; Yoshizawa, Kaname; Kamijo, Nozomi; Ota, Masao; Tanaka, Eiji


Human leukocyte antigen class II molecules confer both susceptibility and progression in Japanese patients with primary biliary cirrhosis
Hepatology,55(2):506-511 2012(Feb.)
Author:Umemura T, Joshita S, Ichijo T, Yoshizawa K, Katsuyama Y, Tanaka E, Ota M, Shinshu PBC Study Group


Genetic polymorphisms in CTLA4 and SLC4A2 are differentially associated with the pathogenesis of primary biliary cirrhosis in Japanese patients
J Gastroenterol,46(10):1203-1212 2011(Oct.)
Author:Aiba Y, Nakamura M, Joshita S, Inamine T, Komori A, Yoshizawa K, Umemura T, Horie H, Migita K, Yatsuhashi H, Nakamuta M, Fukushima N, Saoshiro T, Hayashi S, Kouno H, Ota H, Muro T, Watanabe Y, Nakamura Y, Komeda T, Shimada M, Masaki N, Komatsu T, Yagura M, Sugi K, Koga M, Tsukamoto K, Tanaka E, Ishibashi H, NHOSLJ PBCSGi


Serum interleukin (IL)-10 and IL-12 levels and IL28B gene polymorphisms: pretreatment prediction of treatment failure in chronic hepatitis C
Antivir Ther,16(7):1073-1080 2011(Oct.)
Author:Umemura T, Joshita S, Yoneda S, Katsuyama Y, Ichijo T, Matsumoto A, Yoshizawa K, Ota M, Tanaka E


Early detection of interstitial pneumonia by monitoring KL-6 in a chronic hepatitis C patient undergoing pegylated interferon and ribavirin therapy
Hepatol Res,41(9):904-909 2011(Sep.)
Author:Ichikawa-Yamada Y, Joshita S, Tsukahara Y, Kimura T, Morita S, Kamijo A, Umemura T, Ichijo T, Matsumoto A, Yoshizawa K, Tanaka E


A Case of Pyogenic Liver Abscess Infected with Fusobacterium necrophorum Depicted by Microscopy and Confirmed by Tissue Culture
Intern Med,50(17):1815-1819 2011(Sep.)
Author:Nozawa Y, Joshita S, Fukushima M, Sugiyama Y, Ichikawa Y, Kimura T, Morita S, Kamijo A, Umemura T, Ichijo T, Matsumoto A, Yoshizawa K, Tanaka E


Serum chemokine levels are associated with the outcome of pegylated interferon and ribavirin therapy in patients with chronic hepatitis C
Hepatol Res,41(6):587-593 2011(Jun.)
Author:Yoneda S, Umemura T, Joshita S, Ichijo T, Matsumoto A, Yoshizawa K, Katsuyama Y, Ota M, Tanaka E


Cytokine profiles affecting the pathogenesis of autoimmune hepatitis in Japanese patients
Hepatol Res,41(4):350-357 2011(Apr.)
Author:Kamijo A, Yoshizawa K, Joshita S, Yoneda S, Umemura T, Ichijo T, Matsumoto A, Ota M, Tanaka E


Association of serum cytokine levels with treatment response to pegylated interferon and ribavirin therapy in genotype 1 chronic hepatitis C patients
J Infect Dis,203(8):1087-1095 2011(Mar.)
Author:Yoneda S, Umemura T, Katsuyama Y, Kamijo A, Joshita S, Komatsu M, Ichijo T, Matsumoto A, Yoshizawa K, Ota M, Tanaka E


Clinical significance of immunoglobulin G4-associated autoimmune hepatitis
J Gastroenterol,46 Suppl 1:48-55 2011(Jan.)
Author:Umemura T, Zen Y, Hamano H, Joshita S, Ichijo T, Yoshizawa K, Kiyosawa K, Ota M, Kawa S, Nakanuma Y, Tanaka E


Accurate and simple method for quantification of hepatic fat content using magnetic resonance imaging: a prospective study in biopsy-proven nonalcoholic fatty liver disease
JOURNAL OF GASTROENTEROLOGY,45(12):1263-1271 2010(Dec.)
Author:Hatta, Tomoko; Fujinaga, Yasunari; Kadoya, Masumi; Ueda, Hitoshi; Murayama, Hiroaki; Kurozumi, Masahiro; Ueda, Kazuhiko; Komatsu, Michiharu; Nagaya, Tadanobu; Joshita, Satoru; Kodama, Ryo; Tanaka, Eiji; Uehara, Tsuyoshi; Sano, Kenji; Tanaka, Naoki


Association analysis of cytotoxic T-lymphocyte antigen 4 gene polymorphisms with primary biliary cirrhosis in Japanese patients
JOURNAL OF HEPATOLOGY,53(3):537-541 2010(Sep.)
Author:Joshita, Satoru; Umemura, Takeji; Yoshizawa, Kaname; Katsuyama, Yoshihiko; Tanaka, Eiji; Nakamura, Minoru; Ishibashi, Hiromi; Ota, Masao


Serum Fragmented Cytokeratin 18 Levels Reflect the Histologic Activity Score of Nonalcoholic Fatty Liver Disease More Accurately Than Serum Alanine Aminotransferase Levels
JOURNAL OF CLINICAL GASTROENTEROLOGY,44(6):440-447 2010(Jun.)
Author:Tsutsui, Masaru; Tanaka, Naoki; Kawakubo, Masatomo; Sheena, Yo; Horiuchi, Akira; Komatsu, Michiharu; Nagaya, Tadanobu; Joshita, Satoru; Umemura, Takeji; Ichijo, Tetsuya; Matsumoto, Akihiro; Yoshizawa, Kaname; Aoyama, Toshifumi; Tanaka, Eiji; Sano, Kenji


A2BP1 as a novel susceptible gene for primary biliary cirrhosis in Japanese patients
HUMAN IMMUNOLOGY,71(5):520-524 2010(May)
Author:Joshita, Satoru; Umemura, Takeji; Yoshizawa, Kaname; Katsuyama, Yoshihiko; Tanaka, Eiji; Ota, Masao


A Case of Granulocyte-Colony Stimulating Factor-Producing Hepatocellular Carcinoma Confirmed by Immunohistochemistry
JOURNAL OF KOREAN MEDICAL SCIENCE,25(3):476-480 2010(Mar.)
Author:Joshita, Satoru; Nakazawa, Koh; Koike, Shoichiro; Kamijo, Atsushi; Matsubayashi, Kiyoshi; Miyabayashi, Hideharu; Furuta, Kiyoshi; Kitano, Kiyoshi; Yoshizawa, Kaname; Tanaka, Eiji


A Patient with Advanced Hepatocellular Carcinoma Treated with Sorafenib Tosylate Showed Massive Tumor Lysis with Avoidance of Tumor Lysis syndrome
INTERNAL MEDICINE,49(11):991-994 2010
Author:Joshita, Satoru; Yoshizawa, Kaname; Sano, Kenji; Kobayashi, Satoshi; Sekiguchi, Tomohiro; Morita, Susumu; Kamijo, Atsushi; Komatsu, Michiharu; Umemura, Takeji; Ichijo, Tetsuya; Matsumoto, Akihiro; Tanaka, Eiji


A case of well-differentiated cholangiolocellular carcinoma visualized with contrast-enhanced ultrasonography using Sonazoid
HEPATOLOGY RESEARCH,39(2):207-212 2009(Feb.)
Author:Joshita, Satoru; Ichijo, Tetsuya; Suzuki, Fumitaka; Yokoyama, Takahide; Sugiyama, Yukiko; Fukushima, Mana; Kamijo, Atsushi; Komatsu, Michiharu; Umemura, Takeji; Yoshizawa, Kaname; Miyagawa, Shinichi; Tanaka, Eiji


Primitive Neuroectodermal Tumor as a Differential Diagnosis of CD56-Positive Tumors in Adults
INTERNAL MEDICINE,48(15):1267-1272 2009
Author:Nagaya, Tadanobu; Tanaka, Naoki; Kamijo, Atsushi; Joshita, Satoru; Nakazawa, Koh; Miyabayashi, Hideharu; Yoneda, Suguru; Ito, Tetsuya; Komatsu, Michiharu; Tanaka, Eiji; Kitano, Kiyoshi


Granulocyte-Colony Stimulating Factor-Producing Pancreatic Adenosquamous Carcinoma Showing Aggressive Clinical Course
INTERNAL MEDICINE,48(9):687-691 2009
Author:Joshita, Satoru; Nakazawa, Koh; Sugiyama, Yukiko; Kamijo, Atsushi; Matsubayashi, Kiyoshi; Miyabayashi, Hideharu; Furuta, Kiyoshi; Kitano, Kiyoshi; Kawa, Shigeyuki


Zygomycosis presenting as acute myocardial infarction during hematological malignancies
INTERNAL MEDICINE,47(9):839-842 2008
Author:Joshita, Satoru; Kitano, Kiyoshi; Nagaya, Tadanobu; Kamijo, Atsushi; Nakazawa, Koh; Ishida, Fumihiro


学会発表
DOWN-REGULATION OF SREBP-1C IS ASSOCIATED WITH THE DEVELOPMENT OF BURNED-OUT NASH
the European Association for the Study of the Liver , JOURNAL OF HEPATOLOGY , 52:S373-S374 2010
Author:Nagaya, T.; Tanaka, N.; Komatsu, M.; Joshita, S.; Umemura, T.; Ichijo, T.; Matsumoto, A.; Yoshizawa, K.; Aoyama, T.; Tanaka, E.

社会活動実績

社会活動等
公開講座
20170929 - 20170929 , 肝炎医療従事者等研修会
20110806 - 20110806 , 日本消化器がん検診学会 関東甲信越地方会 超音波部会
20100725 - 20100725 , 肝癌撲滅キャンペーン B型肝炎の治療