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中村宗一郎  ナカムラ ソウイチロウ

教員組織電話番号
教育組織学長・理事FAX番号
職名理事、副学長 教授メールアドレス
住所〒399-4501 長野県上伊那郡南箕輪村8304ホームページURLhttp://karamatsu.shinshu-u.ac.jp/lab/fs/

更新日:2019/08/09

プロフィール

兼担研究科・学部
農学部
研究分野
食品化学
現在の研究課題
アレルギー改善機能をもつ食素材の開発

認知症を含むアミロイドーシス予防抑制機能をもつ食素材の開発

ノロウィルス感染を含むウィルス性食中毒予防抑制機能をもつ食素材の開発

肥満や高血圧症予防抑制機能をもつ食素材の開発

その他,分子表面機能特性に優れた食素材の開発

所属学会
所属学会
日本農学アカデミー

所属学会役職担当
2016- , 日本食品化学会 , 理事
2005- , 日本農芸化学会 , 中部支部会評議員(参与)
1995- , Institute of Food Technologists (USA), Professional Member
2014-2015 , 日本食品化学会 , 評議員
2012-2016 , 日本農芸化学会 , 公益財団法人代議員
2011-2012 , 日本農芸化学会 , 評議員
学歴
出身大学院
1994 , 鳥取大学

出身学校・専攻等(大学院を除く)
1976 , 島根大学

取得学位
博士(農学) , 鳥取大学
受賞学術賞
2014 , 日本農芸化学会2014年度大会トピックス賞
2011 , Certificate of Appreciation for Valuable Contribution and Dedicated Service in the Peer Review of Manuscripts Submitted to ACS Journals (American Chemical Society)
2006 , JFN Award for Academic Excellence from the Korean Society of Food Science and Nutrition (FSN)
2003 , The Most Outstanding Presentation at the 2nd Food Protein Symposium in Vancouver (FSNPB)
1995 , Certificate of Achievement for Satisfactory Completion of Biosym/MSI's Introduction to Molecular Modeling Workshop
研究職歴等
研究職歴
2016- , ソウル国立大学、アジャンクト・プロフェッサー
2005- , 信州大学教授
1999- , 島根大学教授
1976- , 宇部短期大学助手、その後講師、助教授、教授
2000-2005 , ブリティッシュ・コロンビア大学、アジャンクトプロフェッサー
1994-1997 , ブリティッシュ・コロンビア大学、リサーチフェロー

研究職歴以外の職歴
2013-2016 , 客座教授、大連大学

研究活動業績

研究業績(著書・
発表論文等)
著書
Modulation of neuroprotective genes by bioactive food components in senescence-accelerated mice. In “Phytopharmaceuticals for Brain Health”, (Edited by Shahnaz Subhan and Manashi Bagchi)
CRC Press, USA , :323-331 2017
Author:Shigeru Katayama and Soichiro Nakamura


Amyloidogenic proteinsand peptides. In “Biologically Active Food Proteins and Peptides in Health -Fundamental and Clinical Aspects”, (Editedby Y. Mine,E.C.Y. Li-Chan, B. Jiang)
Blackwell Publishing, USA , :87-99 2010
Author:Soichiro Nakamura, Takanobu Owaki, Yuki Maeda, Shigeru Katayama, KosukeNakamura


Site-specific glycosylation using Pichia expression system improves structural stability and antimicrobial activity of human cystatin C. In “Advances in Medicine and Biology”, (Edited by LeonV. Berhardt)
Nova Science Publishers, Inc., New York , :243-254 2010
Author:Soichiro Nakamura, Junya Hata, Kosuke Nakamura, Hao Jing, David D. Kitts, and Shuryo Nakai


Maillard-type neoglycoproteins with multi-functionalities and food safety.In “New Issues in Food Policy, Control and Research”, (Edited byArthur P. Riley)
Nova Science Publishers, Inc., New York , :109-125 2007
Author:Soichiro Nakamura


Drastically reduced antigen-antibody interaction of Fag e 1 by the controlled Maillard-type glycosylation with polysaccharides, in “Advance in Buckwheat Research” (edited by Chai Yan and Zhang Zongwen)
Northwest A&F UniversityPress, , :496-502 2007
Author:Soichiro Nakamura, Yasuhiro Suzuki, Eri Ishikawa, Hao Jing


Cystatin, as a novel bioactive proteinase inhibitor. In “Nutraceutical Proteins and Peptides in Health and Disease ”, (Edited by Y. Mine and F. Shahidi)
Marcel Dekkar Inc., New-York , :pp.243-266 2005
Author:Soichiro Nakamura


Application of a graphic global optimization for protein modification. In"Food for Health in the PacificRim"(edited by Whitaker, J. R., Shahidi, F., Munguia, A. L., Yada, R. and Fuller, G.)
Food&Nutrition Press (Trumbull CT) , :pp. 1-11 1998
Author:Nakai, S., Dou, J., Nakamura, S.


Drastically reduced antigen-antibody interaction of Fag e 1 by the controlled Maillard-type glycosylation with polysaccharides. in “Advances in Buckwheat Research” (edited by Chai Yan and Zhang Zongwen)
Northwest A&F University Press (Yangling, China) , :pp. 496-502 1997
Author:Soichiro Nakamura, Yasuhiro Suzuki, Eri Ishikawa, Hao Jing


Computer-aided optimization of site-directed mutagenesis of Bacillus stearothermophilus neutral protease. In "Functional Propertiesof Proteins and Lipids" (edited by Whitaker, J. R., Shahidi, F., Munguia, A. L.,Yada, R. and Fuller, G.),
American Chemical Society (Washington, DC) , :pp. 19-35 1996
Author:Nakai, S., Nakamura, S., andOgawa, M.


Novel functional properties of glycosylated lysozymes constructed by chemical and genetic modifications. In "Macromolecular Interactions in FoodTechnology" (edited by Parris, N., Kato, A., Creamer, L.K. and Pearce, J.)
American Chemical Society (Washington, DC) , :pp.243-256 1996
Author:Kato, A., Nakamura, S., Takasaki, H., and Maki, S.


New methods for improving functionalityof egg white proteins. In "Egg Uses and Processing Technologies" (edited. by J. S. Sim and S. Nakai)
CAB International (Washington, DC) , :pp. 261-279 1993
Author:Kato, A., Ibrahim, H. R., Nakamura, S., and Kobayashi, K.


Novel macromolecular emulsifier having improved antimicrobial action elaborated by covalent attachment of polysaccharides to lysozyme. In "Food Proteins -Relationship of Functionality andStructure-" (edited by Schwenke, K.D. and Mothes, R.)
VCH (New York) , :pp. 29-39 1993
Author:Nakamura, S., Kato, A., andKobayashi, K.


論文
Enhanced anti-allergic activity of milk casein phosphopeptide by additional phosphorylation in ovalbumin-sensitized mice
Molecules,24:738 2019
Author:Ntshepisa Lebetwa , Yuta Suzuki , Sachi Tanaka , Soichiro Nakamura , Shigeru Katayama


Emerging roles of bioactive peptides on brain health promotion
International Journal of Food Science & Technology (Wiley),54:1949–1955 2019
Author:Shigeru Katayama and Soichiro Nakamura


Fermented rice peptides attenuate scopolamine-induced memory impairment in mice by regulating neurotrophic signaling pathways in the hippocampus
Brain Research (Elsevier),1720:146322 2019
Author:Henry M. Corpuz, Hiroshi Fujii, Soichiro Nakamura, and Shigeru Katayama


Preparation of an allergen-specific immunomodulator by phosphorylation of a major buckwheat globulin allergen, Fag e 1, with diminished IgE response via Tfh cell activation
Jpn. J. Food Chem. Safety,26 2019
Author:Soichiro Nakamura, Shigeru Katayama


Long-term intake of glucoraphanin-enriched kale suppresses skin aging via activating Nrf2 and the TβRII/Smad pathway in SAMP1 mice
J. Agric. Food Chem. (ACS) 2019
Author:Chawalitpong, Supatta ; Ichikawa, Saki; Uchibori, Yuki; Nakamura, Soichiro; Katayama, Shigeru


Biological and Neuroprotective Activity of Thai Edible Plant Extracts
Industrial Crops and Products (Elsevier),124:548-554 2018
Author:Pimmada Junsathian, Kanokwan Yordtong, Shigeru Katayama, Henry M Corpuz, Soichiro Nakamura, Saroat Rawdkuen


Oral immunotherapy with a phosphorylated hypoallergenic allergen ameliorates allergic responses more effectively than intact allergen in a murine model of buckwheat allergy
Molecular Nutrition & Food Research 2018
Author:Shigeru Katayama, Daiki Yamaguchi, Yuta Suzuki, Ahmad M. Al Athamneh, Takakazu Mitani, Rie Satoh, Reiko Teshima, Yoshinori Mine, Soichiro Nakamura


Soybean-Derived Glycine-Arginine Dipeptide Administration Promotes Neurotrophic Factor Expression in the Mouse Brain
J. Agric. Food Chem (ACS),66:7935-7941 2018
Author:Ayano Shimizu, Takakazu Mitani, Sachi Tanaka, Hiroshi Fujii, Motohiro Maebuchi, Yusuke Amiya, Mitsuru Tanaka, Toshiro Matsui, Soichiro Nakamura, Shigeru Katayama


Long-term diet supplementation with Lactobacillus paracasei K71 prevents age-related cognitive decline in senescence-accelerated mouse prone 8
Nutrients,10:762 2018
Author:Henry Marzo Corpuz, Saki Ichikawa, Misa Arimura, Toshihiro Mihara, Takehisa Kumagai, Takakazu Mitani, Soichiro Nakamura, Shigeru Katayama


Theophylline suppresses interleukin-6 expression by inhibiting glucocorticoid receptor signaling in pre-adipocytes
Archives of Biochemistry and Biophysics,646:98–106 2018
Author:Takakazu Mitani, Tomohide Takaya, Naoki Harada, Soichiro Nakamura, Hitoshi Ashida, Ryoichi Yamaji, Shigeru Katayama


Kale supplementation up-regulates HSP70 and suppresses cognitive decline in a mouse model of accelerated senescence
Journal of Functional Foods,44:292-298 2018
Author:Shoko Kushimoto, Yuki Uchibori, Shuichi Yanai, Yuto Suto, Hirofumi Kobayashi, Hidefumi Makabe, Soichiro Nakamura, Shigeru Katayama


Cyperenoic acid suppresses osteoclast differentiation and delays bone loss in a senile osteoporosis mouse model by inhibiting non-canonical NF-kB pathway
Scientific Reports,8(5625 (Article number)) 2018
Author:Supatta Chawalitpong, Ratchanaporn Chokchaisiri, Apichart Suksamrarn, Shigeru Katayama, Takakazu Mitani, Soichiro Nakamura, Ahmad AI Athamneh, Patcharee Ritprajak, Asada Leelahavanichkul, Ratchaneevan Aeimlapah, Narattaphol Charoenphandhu, Tanapat Palaga


Rutinosylated ferulic acid attenuates food allergic response and colitis by up-regulating regulatory T cells in mouse models
Journal of Agricultural and Food Chemistry,65:10730-10737 2017
Author:Shigeru Katayama, Fumiaki Ohno, Takakazu Mitani, Hiroshi Akiyama, Soichiro Nakamura


Theobromine suppresses adipogenesis through enhancement of CCAAT-enhancer-binding protein degradation by adenosine receptor A1
BBA - Molecular Cell Research,1864:2438-2448 2017
Author:Takakazu Mitani, Shun Watanabe, Yasukiyo Yoshioka, Shigeru Katayama, Soichiro Nakamura, Hitoshi Ashida


Solventless extraction methods for immature fruits: Evaluation of their antioxidant and cytoprotective activities
Food Chemistry,221:1388-1393 2017
Author:Ming Yuan Heng, Shigeru Katayama, Takakazu Mitani, Eng Shi Ong, Soichiro Nakamura


Role of phosphate groups on antiviral activity of casein phosphopeptide against feline calicivirus as a surrogate for norovirus
Journal of the Science of Food and Agriculture,97:1939-1944 2017
Author:Lebetwa, N., Mitani, T., Nakamura, S., Katayama, S.


Effects of sesaminol feeding on brain Aβ accumulation in a senescence-accelerated mouse-prone 8
Journal of Agricultural and Food Chemistry,64:4908-4913 2016
Author:Katayama, S., Sugiyama, H., Kushimoto, S., Uchiyama, Y., Hirano, M., Nakamura, S.


Intestinal immunomodulatory effects of a hypoallergenic buckwheat Fag e 1 prepared by Maillard-type glycation with a mannan type-polysaccharide
Japanese Journal of Food Chemistry and Safety,23:72-79 2016
Author:Katayama, S., Tazawa, S., Kassai, M., Mitani, T., Nakamura, S.


Biophysical characterization of the domain association between cytosolic A and B domains of the mannitol transporter enzymes IIMtl in the presence and absence of a connecting linker
Protein Science,25:1803-1811 2016
Author:Ko On Lee, Eun-Hee Kim, Gowoon Kim, Jea Yeon Jung, Shigeru Katayama, Soichiro Nakamura, Jeong-Yong Suh


Antioxidant and cytoprotective activities of extracts prepared from fruit and vegetable wastes and by-products
Food Chemistry,167:358-362 2015
Author:Faisal Kabir, Wei Wei Tow, Yasunori Hamauzu, Shigeru Katayama, Sachi Tanaka, Soichiro Nakamura


Attenuation of Allergic Immune Response Phenotype by Mannosylated Egg White in Orally Induced Allergy in Balb/c Mice
J. Agric. Food Chem.,62:9479-9487 2014
Author:Prithy Rupa, Soichiro Nakamura, Shigeru Katayama, Yoshinori Mine


Improvement of surface functionalities, including allergenicity attenuation, of whole buckwheat protein fraction by Maillard-type glycation with dextran
Prev. Nutr. Food Sci.,19:327-332 2014
Author:Shigeru Tazawa, Shigeru Katayama, Masahiro Hirabayashi, Daiki Yamaguchi, Soichiro Nakamura


Antimicrobial effects of chlorogenic acid and related compounds
Appl. Biol. Chem.,57:359−365 2014
Author:Faisal Kabir, Shigeru Katayama, Noriko Tanji,Soichiro Nakamura


Oral administration of soy peptides suppresses cognitive decline by induction of neurotrophic factors in SAMP8 mice
J. Agric. Food Chem.,62:3563-3569 2014
Author:Shigeru Katayama, Rie Imai,Haruka Sugiyama, Soichiro Nakamura


Changes in mouse gastrointestinal microbial ecology with the ingestion of kale
Beneficial Microbes,5:345-350 2014
Author:Yutaka Uyeno, Shigeru Katayama, Soichiro Nakamura


Enhanced anti-amyloidal activity of hydroxy cinnamic acids by enzymatic esterification with alkyl alcohols
Biotechnology and Applied Biochemistry,61:401-407 2014
Author:Kondo, H., Katayama, S., Sugiyama, H., Nakamura, S.


Effects of ovalbumin glycoconjugates on alleviation of arally induced egg allergy in mice via dendritic-cell maturation and T-cell activation
Molecular Nutrition&Food Research,58:405-417 2014
Author:Prithy Rupa, Soichiro Nakamura, Shigeru Katayama, Yoshinori Mine


Prevention of allergic disease development and symptoms by food factors.
Current Pharmaceutical Design (CPD),20:892-905 2014
Author:Hiroshi Akiyama, Shigeru Katayama, Tomomasa Kanda, Mari Maeda-Yamamoto, Mamoru Totsuka, Shingo Takahashi, Toshihiko Shoji, Takahiro Inakuma, Soichiro Nakamura


Enzymatic synthesis of novel phenol acid rutinosides using rutinase and their antiviral activity in vitro
J. Agric. Food Chem.,61:9617-9622 2013
Author:Shigeru Katayama, Fumiaki Ohno, Yuki Yamauchi, Miyuki Kato, Hidefumi Makabe, Soichiro Nakamura


Functional expression of amyloidogenic human stefins A and B in Pichia pastoris
Biotechnology and Applied Biochemistry,60:283-288 2013
Author:Kosuke Nakamura, Yuki Maeda, Kensuke Morimoto, Shigeru Katayama, Kondo Kazunari, Soichiro Nakamura


Apple polyphenols suppress antigen presentation of ovalbumin by THP-1-derived dendritic cells.
Food Chemistry,138:757-761 2013
Author:Shigeru Katayama; Takuya Kukita; Eri Ishikawa; Syohei Nakashima; Susumu Masuda; Tomomasa Kanda; Hiroshi Akiyama; Reiko Teshima; Soichiro Nakamura


Analysis of Mechanisms of Induction of an Insulin-Inducible TranscriptionFactor, SHARP-2, by (-)-Epigallocatechin-3-gallate.
Journal of Agricultural and Food Chemistry,60:9850−9855 2012
Author:Ayumi Haneishi, Katsuhiro Takagi, Kosuke Asano, Soichiro Nakamura, and Kazuya Yamada


(-)-Epigallocatechin-3-gallate stimulates both AMP-activated protein kinase and nuclear factor-kappa B signaling pathways
Food Chemistry,134:783-788 2012
Author:Kosuke Asano, Katsuhiro Takagi, Ayumi Haneishi, Soichiro Nakamura, Kazuya Yamada


Improving surface functional properties of Tofu whey-derived peptidesby chemical modification with fatty acids
J. Food Sci.,77(4):C333-C339 2012
Author:Matemu, A.O., Nakamura, K., Kayahara, H., Murasawa, H., Katayama, S. and Nakamura, S.


Apricot carotenoids possess potent anti-amyloidogenic activity in vitro
J. Agric. Food Chem.,59:12691-12696 2011
Author:Katayama, Shigeru; Ogawa, Hirofumi; Nakamura, Soichiro


(-)-Epigallocatechin-3-Gallate Enhances the Expression of an Insulin-Inducible Transcription Factor Gene via a Phosphoinositide 3-Kinase/ Atypical Protein Kinase C Lambda Pathway
J. Agric. Food Chem.,59:13360-13364 2011
Author:Asano, Kosuke; Takagi, Katsuhiro; Haneishi, Ayumi; Yamamoto, Taichi; Tanaka, Takashi; Noguchi, Tamio; Nakamura, Soichiro; Yamada, Kazuya


Improved emulsifying properties of soy proteinsby lipophilization with saturated fatty acids
Food Chemistry,124:596-602 2011
Author:Matemu, A.O., Katayama, S., and Nakamura, S.


Enhanced antiviral activity of soybean β-conglycinin-derived peptides by acylation with saturated fattyacids
J. Food Sci.,76:299-304 2011
Author:Athanasia O. Matemu, Kosuke Nakamura, Hisataka Kayahara, Hisashi Murasawa, Shigeru Katayama, Soichiro Nakamura


Genistein stimulates the insulin-dependent signaling pathway
Frontiers in Bioscience-Landmark,3:1534-1540 2011
Author:Ayumi Haneishi, Katsuhiro Takagi, Kosuke Asano, Soichiro Nakamura, Norio Kagawa, Kazuya Yamada


Suppressed fat accumulation in rats fed with histidine-enriched diet
Journal of Food Science and Nutrition,15:1-6 2010
Author:Endo, M., Kasaoka, S., Takizawa, M., Goto, K., Nakajima, S., Moon, S-K. Kim, I-S. Jeong, B-Y, and Nakamura, S.


Comparisons of Korean and Japanese College Students' Eating Habits and Food Preferences
J Korean Soc Food Sci Nutr,39:1619-1626 2010
Author:Kyoung Ae Lee, Bo-Young Jeong, Soo-Kyung Moon, In-SooKim, Shigeru Nakajima, Soichiro Nakamura


Importance of size and charge of carbohydrate chains inthe preperation of functional glycoproteins with excellent emulsifying properties from tofu whey
Food Chemistry,114:1328-1334 2009
Author:Matemu, A.O., Nakamura, K., Kayahara, H., Murasawa, H. and Nakamura, S.


Modulation of Immunoresponse in BALB/c Mice by Oral Administration of Fag e 1-Glucomannan Conjugate
J. Agric. Food Chem.,57:9787-9792 2009
Author:Suzuki, Y., Kassai, M., Hirose, T., Katayama, S., Nakamura, K., Akiyama, H., Teshima, R., Nakamura, S.


Obliteration of egg allergic immune response by genetically modified ovomucoid third domain in Balb/c mice
J. Clin. Biochem. Nutr.,43:74-77 2008
Author:Rupa, P., Nakamura, S., and Mine, Y.


Modulation of IgE production and Th1/2 cytokine response in balb/c mice by glycosylated ovomucoid third domain.
J. Clin. Biochem. Nutr.,43:307-310 2008
Author:Rupa, P., Nakamura, S., and Mine, Y.


Genetically glycosylated ovomucoid third domain can modulate Immunoglobulin E antibody production and cytokine response in BALB/c mice
Clin. Experim. Allergy,37:918-928 2007
Author:Rupa, P., Nakamura, S., and Mine, Y.


Reduction of in vitro allergenicity of buckwheat Fag e 1 through the Maillard-type glycosylation with polysaccharides
Food Chemistry,109:538-545 2007
Author:Nakamura, S., Suzuki, Y., Ishikawa, E., Yakushi, T., Jing, H., Miyamoto, T. and Hashizume, K.


Comparisons of Korean adults’ eating habits, foodpreferences, and nutrition intake by generation
Korean Journal of Nutrition,39:494-504 2006
Author:Kyoung-Ae Lee, Bo-Young Jeong, Soo-Kyung Moon, In-Soo Kim, Soichiro Nakamura


Functionaland biological activities ofmedium and long chain fatty acid lipophilized casein glycomacropeptides
Food Chemistry,97:310-317 2006
Author:Wong, P., Nakamura, S., Kitts, D.


Preparation ofbioactive and surface functional oligomannosyl neoglycoprotein using extracellular pH-sensitive glycosylation of mutant lysozyme having N-linked signal sequence in yeast
Bioconjugate Chem.,17:1170-1177 2006
Author:Nakamura, S., Ban, M., and Kato, A.


Calcium enriched casein phosphopeptide stimulates release ofIL-6 cytokine in human epithelial intestinal cell line
J. Dairy Research,73:44–48 2006
Author:Kitts, D.D. and Nakamura, S.


Comparisons of Korean adults’ eating habits, food preferences, and nutrition intake by generation
Korean Journal of Nutrition,39:494-504 2006
Author:Kyoung-Ae Lee, Bo-Young Jeong, Soo-Kyung Moon, In-Soo Kim, Soichiro Nakamura


Production and use of Maillard-type glycoproteins
J. Medicinal Food,8:291-298 2005
Author:Jing H. and Nakamura, S.


Enhanced anti-rotavious action of human cystatin C by site-specific glycosylation in yeast
Bioconjugate Chem.,15:1289-1296 2004
Author:Nakamura, S., Hata, J., Kawamukai, M., Matsuda, H., Ogawa, M., Nakamura, K., Jing, H., Kitts, D.D., and Nakai, S.


A computer-aided strategyfor structure-function relation studyof food proteins using unsupervised data mining
Int. J. Food Properties,6:25-47 2003
Author:Nakai, S., Ogawa, M., Nakamura, S., Dou, J., and Funame, K.


Food safety of functional neoglycoproteins prepared by covalent attachment of galacotomannan to food proteins
Nutraceuticals and Food (J.Med. Food) (IF=1.839),7:139-145 2002
Author:Nakamura, S., Dokai, K., Matsuura, M., and Saeki, H.


Enhancement of proteinase inhibitoryactivity of recombinant human cystatin C using random-centroid optimization.
Biochim. Biophys. Acta,1599:115-124 2002
Author:Ogawa, M., Nakamura, S., Scaman, C., Jing, H., Kitts, D.D., and Nakai, S.


Green-leaf-derived C6-aroma compounds with potent antibacterial action that act both on Gram-negative and Gram-positive bacteria
J. Agric. Food Chem.,50:7639-7644 2002
Author:Nakamura, S. and Hatanaka, A.


Bactericidal activity ofegg yolk phosvitin against Escherichia coli under the influence of thermal stress
J. Agric. Food Chem.,48:1503-1506 2000
Author:Khan, M.A.S., Nakamura, S., Ogawa, M., Akita, E., Azakami, H., and Kato, A.


Multiffunctional biopolymer prepared by covalent attachment of galactomannan to egg-white proteins through naturally occurring Maillard reaction
Nahrung/Food (Molecular Nutrition&Food Research),44:201-206 2000
Author:Nakamura, S. and Kato, A.


Rapid formation of biologically active neoglycoprotein from lysozyme and xyloglucan hydrolysates through naturally occurring Maillard reaction
J. Food Science and Nutrition,5:65-69 2000
Author:Nakamura, S., Ogawa, M., Saeki, H., Saito, M., Gotoh, M., and Hwang, J-K.


Enthalpic destabilization of glycosylated lysozymes constructed by genetic modification
Biochim. Biophys. Acta,1481:88-96 2000
Author:Kato A., Nakamura, S., Ban M., Azakami H., and Yutani K.


Improving the surface functionality of curdlan by conjugationwith unfolding protein through naturally occurring Maillard reaction
J. Food Science and Nutrition,5:200-204 2000
Author:Nakamura, S., Ogawa, M., Saeki, H., Saito, M., Miyasaka, S., Hata, J.


Application of a metal-chelating protein, phosvitin to the establishment ofsafe food system
Metal Ions,6:544-546 2000
Author:Gotoh,M., Nakamura, S., Gohya, Y., and Hobara, T.


Gas chromatography/principal component similarity system fordetection of E. coli and S. aureus contaminating salmon and hamburger
J.Agric. Food Chem.,47:576-583 1999
Author:Nakai, S., Wang, Z.H., Dou, J., Nakamura, S., Ogawa, M., and Nakai, E., and Vanderstoep, J.


Macromolecular antimicrobial glycoprotein, achacin, expressed in a methylotrophic yeast Pichia pastoris
FEBS Letters,448:41-44 1999
Author:Ogawa, M., Nakamura, S., Atsuchi, T., Tamiya, T., Tsuchiya, T., and Nakai, S.


Raman spectroscopic study of changes in fish actomyosin during setting
J. Agric. Food Chem.,47:3309-3318 1999
Author:Ogawa, M., Nakamura, S., Horimoto, Y., An, H., Tsuchiya, T., and Nakai, S.


An automated analytical system for quality assurance of foods by applying a new classification method to chromatographicdata
Leatherhead Food Research,2:310-323 1999
Author:Nakai, S., Wang, Z.H., Nakamura, S., Ogawa, M., Dou, J., Ogihara, H., Horimoto, Y.,Nakai, E., and Skura, B.


Antioxidant activity of a Maillard-type phosvitin-galactomannan conjugate with emulsifying properties and heat stability.
J. Agric. Food Chem.,46:3958-3963 1998
Author:Nakamura,S., Ogawa, M., Nakai, S., Kato, A., and Kitts, D.D.


Effects of polymannosylation of recombinant cystatin C in yeast on its stability and activity.
J. Agric. Food Chem.,46:2882-2887, 1998
Author:Nakamura, S., Ogawa, M., and Nakai, S.


Double-glycosylated lysozyme at positions 19 and 49 constructed by genetic modification andits surface functional properties
J. Agric. Food Chem.,46:2433-2438 1998
Author:Shu,Y., Maki,S., Nakamura, S., and Kato, A.


Effects of proline substitution of the active site helix on dipeptidesynthesis mediatedby Bacillus stearothermophilus neutral protease
Nahrung/Food (Molecular Nutrition&Food Research),42:131-134 1998
Author:Nakamura, S. and Nakai, S.


Production of genetically modified lysozymes having extreme heat stability and antimicrobial activity against Gram-negative bacteria in yeast and in plant
Nahrung/Food (Molecular Nutrition&Food Research),42:128-130 1998
Author:Kato, A., Nakamura, S., Ibrahim, H., and Kato, M.


Application of polymannosylated cystatin to surimi from roe-herring to prevent gel weakening
FEBS Letters,427:252-254 1998
Author:Nakamura, S., Ogawa, M., Saito, M., and Nakai, S.


The role of polysaccharide-chain attachment to lysozyme in the excellent emulsifying properties of polymannosyl lysozyme
Nahrung/Food (Molecular Nutrition&Food Research),42:68-70 1998
Author:Shu, Y., Nakamura, S., and Kato, A.


Optimization of site-directed mutagenesis. 2. Application of random-centroid optimization to one-site mutation of Bacillus stearothermophilus neutral protease to improve thermostability
J. Agric.Food Chem.,46,:1655-1661 1998
Author:Nakai, S., Nakamura, S., and Scaman, C. H.


Improving the thermostability of Bacillus stearothermophilus neutral protease by introducingproline into the active sitehelix
Protein Engineering,10:1263-1269 1997
Author:Nakamura,S., Tanaka, T., Yada, Y. R., and Nakai, S.


Protective effect of lysozyme-galactomannan or lysozymepalmitic acid conjugates against Edwardsiella tarda infection in carp, Cyprinus carpio L
FEBS Letters,383:251-254 1996
Author:Nakamura, S., Gohya, Y., Losso, J. N., Nakai, S., and Kato, A.


Effects of the length of polysaccharide chains on the functional properties of the Maillard-type lysozyme polysaccharide conjugate.
J. Agric.Food Chem.,44:2544-2548 1996
Author:Shu, Y., Sahara, S., Nakamura, S., and Kato, A.


Role of positive charge oflysozyme in the excellent emulsifying properties of Maillard-type lysozyme-polysaccharideconjugate
J. Agric.Food Chem.,42:2688-2691. 1994
Author:Nakamura, S., Kobayashi, K., andKato, A.


Simplified and rapid enumeration of proteolytic bacteria in water using the plate-MPN technique
Suisanzosyoku,42:567-570. 1994
Author:Gohya, Y and Nakamura, S.


Novel surface functional properties of polymannosyl lysozyme constructed bygenetic modification
FEBS Letters,328:259-262 1993
Author:Nakamura, S., Kobayashi, K., and Kato, A.


Hyperglycosylation of hen egg white lysozyme in yeast
J. Biol. Chem.,268:12706-12712. 1993
Author:Nakamura, S., Takasaki, H., Kobayashi, K., and Kato, A.


Bifunctional lysozyme-galactomannan conjugate having excellent emulsifying properties and bactericidal effect
J. Agric. Food Chem.,40:735-739 1992
Author:Nakamura,S., Kato, A., and Kobayashi, K.


Enhanced antioxidative effect of ovalbumin due to covalent binding of polysaccharides
J. Agric. Food Chem.,40:2033-2037 1992
Author:Nakamura, S., Kato, A., and Kobayashi,K.


New antimicrobial characteristics of lysozyme-dextran conjugate
J. Agric. Food Chem.,39:647-650 1991
Author:Nakamura,S., Kato, A., and Kobayashi, K.


Novel bifunctional lysozyme-dextran conjugate that acts on both Gram-negative and Gram-positive bacteria
Agric. Biol. Chem. (Bioscience Biotechnology and Biochemistry),54:3057-3059 1990
Author:Nakamura, S., Kato, A., and Kobayashi, K.


学会発表
Neuromodulatory effects of soybean-derived peptides on BDNF expression and neurogenesis
ISNFF2018, Vancouver, BC, Canada 2018
Author:Shigeru Katayama, Takakazu Mitani, Soichiro Nakamura


Effects of phosphorylation on the structure and enzymatic digestibility of buckwheat allergen, Fag e 2
INSFF2018, Vancouver, BC, Canada 2018
Author:Ahmad Athamneh, Takakazu Mitani, Soichiro Nakamura, Shigeru Katayama


Functional properties of novel ferulicacis-rutinoside enzymatically synthesized using rutinose
ISNFF2018, Vancouver, BC, Canada 2018
Author:Kanako Matsumoto, Takakazu Mitani, HyunYoung Park, Dhiraj A. Vattem, Soichiro Nakamura, Shigeru Katayama


Bioactive peptides for brain health and its mechanistic exploration
AOCS , 2018 AOCS Annual Meeting & Expo 2018
Author:Shigeru Katayama, Takakazu Mitani, Soichiro Nakamura


Pressurized hot-water extraction for the of whole Coptis. sp: An evaluation of the chemical content and bioactivity
The 21st International Solvent Extraction Conference, Miyazaki, Japan 2017(Nov. 05)
Author:Ming Yuan Heng, Shigeru Katayama, Takakazu Mitani, Eng Shi Ong, Soichiro Nakamura


Protective effects of amazake peptides against H2O2-induced oxidative stress in SK-N-SH cells
Food Chemistry and Technology (FCT) , III International Conference on Food Chemistry and Technology (FCT) 2017 2017(Nov. 02)
Author:Henry M. Corpus, Shigeru Katayama, Takakazu Mitani, Soichiro Nakamura


Enzymatic synthesis of novel rutinoside using rutinase and its functional properties (Best Poster Award)
Food Chemistry and Technology (FCT) , III International Conference on Food Chemistry and Technology (FCT) 2017 2017(Nov. 02)
Author:Kanako Matsumoto, Shigeru Katayama, Fumiaki Ohno, Takakazu Mitani, Soichiro Nakamura


Long-term dietary intake of kale cultivar with high content of glucoraphanin suppresses skin aging in senescence-accelerated mouse prone 1 (Best Poster Award)
Food Chemistry and Technology (FCT) , III International Conference on Food Chemistry and Technology (FCT) 2017 2017(Nov. 02)
Author:Saki Ichikawa, Shigeru Katayama, Yuki Uchibori, Takakazu Mitani, Tomohiro Ohno, Soichiro Nakamura


Hypoallergenic phosphorylated buck wheat proteins inducing oral tolerance
International Society for Nutraceuticals and Functional Foods (ISNFF) , ISNFF 2017 2017(Oct. 24)
Author:Shigeru Katayama, Takakazu Mitani, Soichiro Nakamura


Molecular design of novel phenylpropanoid-derived anti-amyloidal compounds using amyloidogenic peptide-linked quantum dot probe (Poster Award)
International Society for Nutraceuticals and Functional Foods (ISNFF) 2017 , ISNFF 2017 2017(Oct. 24)
Author:Soichiro Nakamura,Masaki Nakabayashi,Noriko Tanji,Takakazu Mitani,Kiyotaka Tokuraku,Shigeru Katayama


Japanese fermented soybean paste promotes BDNF expression in primary cultured astrocytes
International Joint Seminar 2016 between Sejong University and Shinshu University, Seoul, Korea 2016(Dec. 08)
Author:Misa Arimura, Katayama, Takakazu, Mitani, Soichiro, Nakamura


The effects of agaro-oligosaccarides on tight junction in Caco-2 intestinal epithelial cells
International Joint Seminar 2016 between Sejong University and Shinshu University, Seoul, Korea 2016(Dec. 08)
Author:Jun Bai, Shigeru Katayama, Takakazu Mitani, Soichiro Nakamura


Phosphate groups enhance antiviral activity of CPP III against Noro virus
2016 Korean-Japan Joint Symposium on Bioscience, Seoul, Korea 2016(Nov. 07)
Author:Ntshepisa Lebetwa, Shigeru Katayama, Takakazu Mitani, Soichiro Nakamura


Green techniques for the extraction of botanicals
2016 Korean-Japan Joint Symposium on Bioscience, Seoul, Korea 2016(Nov. 07)
Author:Ming Yuan Heng, Shigeru Katayama, Takakazu Mitani, Eng Shi Ong, Soichiro Nakamura


Amazake-derived peptides reduce H2O2-induced oxidative stress through the upregulation of the neuroprotective genes in SK-N-SH cells
ISNFF2016, Orlando, USA 2016(Oct. 09)
Author:Corpuz, H.M., Mitani, T., Katayama, S., Nakamura, S.


Soybean-derived basic peptides enhance production of neurotrophic factor in primary cultured astrocytes
ISNFF2016, Orlando, USA 2016(Oct. 09)
Author:Shimizu, A., Mitani, T., Nakamura, S., Katayama, S.


Effects of soy peptides on cognitive performance in senescence-accelerated mice and elderly people
ISNFF2016, Orlando, USA 2016(Oct. 09)
Author:Katayama, S., Shimizu, A., Mitani, T., Maebuchi, M., Nakamura, S.


Immunological tolerance effects of attenuated buckwheat allergens prepared by dry-heating with pyrophosphate
Pacifichem 2015, Hawai, USA 2015(Dec. 17)
Author:Daiki Yamaguchi, Shigeru Katayama, Soichiro Nakamura


Screening for a candidate inducing immune tolerance using TGF-secretuion system from dendritic cell
Pacifichem 2015, Hawai, USA 2015(Dec. 17)
Author:Fumiaki Ohno, Shigeru Katayama, Soichiro Nakamura


Modulation of neuroprotective genes by natural dietary bioactive compounds in senescence-accelerated mice
Pacifichem 2015, Hawai, USA 2015(Dec. 17)
Author:Shigeru Katayama and Soichiro Nakamura


Emerging green technologies for the chemical standardization of botanicals and herbal preparations,
Pacifichem 2015, Hawai, USA 2015(Dec. 17)
Author:Heng Ming Yuan, Ong Eng Shi, Shigeru Katayama, Soichiro Nakamura


Role of phosphate groups on anti-FCV activity of casein phosphopeptide (CPP III)
Pacifichem 2015, Hawai, USA 2015(Dec. 17)
Author:Ntshepisa Lebetwa, Shigeru Katayama, Soichiro Nakamura


Esterification can lead toan improvement of anti-amyloidal effects and neuroprotective effects of cinnamic acid derivatives
The 2nd International Conference on Agriculture and Agro-industry, Chiang-Rai, Thailand 2014(Nov. 20)
Author:Noriko Tanji, Shigeru Katayama, Hazuki Kondo, Soichiro Nakamura


In vivo and in vitro anti-allergic effects of phenolic compounds from Jerusalem artichoke (Helianthus tuberosus L.) tubers
The 2nd International Conference on Agriculture and Agro-industry, Chiang-Rai, Thailand 2014(Nov. 20)
Author:Noguchi Masanari, Shigeru Katayama, Hidefumi Makabe, Soichiro Nakamura


Anti-viral activity of novel glycosylated phenolic compounds in vitro
The 17th World Congress of Food Science&Technology (IUFoST 2014), Montreal, QC Canada 2014(Aug. 20)
Author:Fumiaki Ohno, Shigeru Katayama, Soichiro Nakamura


Anti-amyloidogenicities of catechol lignans converted fromsesamin and sesaminol under subcritical water condition
The 105th Annual Meeting&Expo, San Antonio, USA 2014(May 06)
Author:Soichiro Nakamura and Shigeru Katayama


Molecular design of anti-amyloidal phenolic compounds through esterification, glycosylation, and partial hydrolysis
Mae Fan Luang University, Thailand , International Symposium on Nutraceuticals and FunctionalFoods 2014(Mar. 25)
Author:Soichiro Nakamura and Shigeru Katayama


Development of DC-like THP-1 cell and its application for screening of anti-allergic compounds
Pharma-Nutrition 2013 2013(Apr. 15)
Author:S. Katayama, T. Kukita, S. Nakamura


Overexpression of bioactive human stefins by codon optimization in Pichia pastoris
Pharma-Nutrition 2013 2013(Apr. 15)
Author:S. Nakamura, K. Morimoto, S. Katayama, K. Nakamura


Development of a novel heterogeneous and homogeneous gene screening method for detecting unauthorized genetically modified rice in processed rice products
Pharma-Nutrition 2013 2013(Apr. 15)
Author:K. Nakamura, T. Kobayashi, S. Nakamura, K. Kondo,R. Teshima


Changes in mouse gastrointestinal microbial ecology by the ingestion of kale
SGM Spring Conference 2013 2013(Mar. 25)
Author:Yutaka Uyeno, Shigeru Katayama, Soichiro Nakamura


Production of Amyloidgenic ApoA-II by cell-free protein synthesis and its possible application
Protein Island Matsuyama International Symposium 2012 2012(Sep. 25)
Author:Takahiro Fukumoto , Shigeru Katayama , Akira Nozawa , Yuzuru Tozawa , Soichiro Nakamura


Screening of naturally-occurring food compounds expecting prevention effects against amyloidosisincluding Alzheimer-type dementia and modification of their functionalities by lipophilization, glycolsylation, and partial hydrolysis.
The 6th symposium for comparative studies on food intake and nutrition between Korea and Japan, Jinju, Korea 2012(Aug. 26)
Author:Soichiro Nakamura and ShigeruKatayama


Antioxidant activity of casein phosphopeptides with and without prior to Maillard glycosylation
ISNFF 2012, USA 2012
Author:David D. Kitts and Soichiro Nakamura


Molecular design of anti-amyloidal phenolic compounds using amyloidogenic proteins and peptides.
ISNFF 2012 2012
Author:Soichiro Nakamura and Shigeru Katayama


Functional properties of melanoidin prepared by enzymatically processed tartary buckwheat.
ISNFF 2012 2012
Author:Rie Imai, Shigeru Katayama, Soichiro Nakamura


Establishment of an in vitro screening assay for allergenicity of proteins using dendritic cells differentiated from THP-1.
ISNFF2012 2012
Author:Takuya Kukita, Shigeru Katayama, Hiroshi Akiyama, Soichiro Nakamura


Effects of feeding the buckwheat major allergens glycosylated with glucomannan on their allergenicities.
ISNFF 2012 2012
Author:Yasuko Kimura, Shigeru Katayama, Shigeru Tazawa, Hiroshi Akiyama, Reiko Teshima, Soichiro Nakamura


Enhanced anti-viral activity of novel glycosylated phenolic compounds.
ISNFF 2012 2012
Author:Yuki Yamauchi, Shigeru Katayama,Chihiro Hata,Yuta Yamaguchi, Soichiro Nakamura


Development of human dendritic cell-based in vitro assays for assessment of the potential allergenicity of foods and its anti-allergic compounds.
ISNFF 2012 2012
Author:Shigeru Katayama, Takuya Kukita, Soichiro Nakamura


Anti-amyloidal activities of apricot-derived carotenoids.
ISNFF2012 2012
Author:Haruka Sugiyama, Shigeru Katayama, Hirofumi Ogawa, Soichiro Nakamura


Amyloidogenicities of artificially synthesized human stefins A and B.
ISNFF2012 2012
Author:Kensuke Morimoto, Shigeru Katayama, Takahiro Fukumoto, Kosuke Nakamura, Soichiro Nakamura


Upregulation of heat shock protein HSP70 in senescence-accelerated mice SAMP8 by long-term intake of kale.
ISNFF2012 2012
Author:Shoko Kushimoto, Shigeru Katayama, Yuto Suto, Soichiro Nakamura


Aanti-viral activity of rhamnoglycosylated phenolic compounds
The 5th Rare Sugar Congress, Kagawa, Japan 2011
Author:Yuki Yamauchi, Shigeru Katayama,Soichiro Nakamura


Immuomodulation effect of ovalbumin-acid polysaccharides conjugate
The 5th Rare Sugar Congress, Kagawa, Japan 2011
Author:Yuta Yamaguchi, Shigeru Katayama, Takuya Kukita, Eri Ishikawa, Hiroshi Akiyama, and Soichiro Nakamura


Analysis of T cell epitopes of a major buckwheat allergen, Fag e 2, by using cell-free protein synthesis system
The 9th Protein Island Matsuyama (PIM) Symposium on Cell-Free Sciences,Ehime, Japan 2011
Author:Yasuko Kimura, Shigeru Katayama, Reiko Teshima, Hiroshi Akiyama, Akira Nozawa, Yuzuru Tozawa, and Soichiro Nakamura


Anti-FCV activity of acylated 7S and 11S-derived peptides.
Annual Meeting of Japan Society for Bioscience, Biotechnology, and Agrochemistry 2010,Tokyo, Japan 2010
Author:Matemu, A.O., Kayahara, H., Murasawa, H., Katayama,S. and Nakamura, S.


Suppressive effect of histidine on energy intake -Results of nutrition survey in 2006-2008-
9th Japan-Korea Joint Seminar on Fisheries Sciences, Gangnung, Korea 2010
Author:Shigeru Nakajima, Soichiro Nakamura, Bo-young Jeong, Soo-Kyung Moon, In-Soo Kim, Kyoung-Ae Lee, Hiroki Saeki


Influences of food habits and food preferences on histidine/protein intake -Results of survey both in Korea and Japan at 2006-2008-
9th Japan-Korea Joint Seminar on Fisheries Sciences, Gangnung, Korea 2010
Author:Shigeru Nakajima, Soichiro Nakamura, Bo-young Jeong, Soo-Kyung Moon, In-Soo Kim, Kyoung-Ae Lee, Hiroki Saeki


Further utilization of by-products and wates from fruits and vegetables for the promotion of sustainable agriculture.
The 5th symposium for comparative studies on food intake and nutrition between Korea and Japan 2010
Author:Soichiro Nakamura


Comparison of food habits and preferences in Korean and Japanese female university students.
The 5th symposium for comparativestudies on food intakeand nutrition between Korea and Japan 2010
Author:Soo-Kyung Moon, In-Soo Kim, Bo-Young Jeong,Kyoung-Ae Lee, Hiroki Saeki, Shigeru Nakajima, Soichiro Nakamura


Oxidativestress modulating effect of soya-saponin in vitro.
PacifiChem 2010 2010
Author:Fumi Kuroiwa, Shigeru Katayama, Soichiro Nakamura


Anti-amyloidogenic effects of apricots carotenoids on amyloid β-protein.
PacifiChem2010 2010
Author:ShigeruKatayama, Hirofumi Ogawa, Hideaki Iwai, Soichirou Nakamura


Functional-structural relationships of polyphenols in GSH synthesis.
PacifiChem 2010 2010
Author:Shigeru Katayama, Hirofumi Ogawa, Hideaki Iwai, Soichirou Nakamura


Synergistic effect of aminoacids on anti-oxidative stress activity of soya-saponin.
PacifiChem 2010 2010
Author:Shigeru Katayama, Fumi Kuroiwa, Soichiro Nakamura


Anti-amyloidal effects of novel amphiphilic phenolic compounds prepared by enzymatic lipophilization.
PacifiChem 2010 2010
Author:Soichiro Nakamura, Hazuki Kondo, and Shigeru Katayama


Immunomodulatory effect of a hypoallergenic buckwheat Fage1 prepared by Maillard-type glycosylation with yeast glucomannan.
PacifiChem 2010 2010
Author:Soichiro Nakamura, Yasuhiro Suzuki, Masahiro Kassai, Kosuke Nakamura, Hiroshi Akiyama, Reiko Teshima, and Shigeru Katayama


Multi-functional hybrid proteins prepared from tofuwhey by glycosylation and acylation.
PacifiChem 2010 2010
Author:Athanasia Oswald Matemu, Hisataka Kayahara, Hisashi Murasawa, ShigeruKatayama, and Soichiro Nakamura


Enhanced anti-FCV activity of 7S and 11S-derived peptides by acylation with fatty acids.
PacifiChem 2010 2010
Author:Athanasia Oswald Matemu, Kosuke Nakamura, Shigeru Katayama, and Soichiro Nakamura


Lipophilized glycolmacropeptide as a potential stresses modulator against health hazard including Salmonella enteritidis and Feline calicivirus infections.
PacifiChem 2010 2010
Author:Atsumi Morita, Peter Y.Y. Wong,David D. Kitts, Shigeru Katayama, and Soichiro Nakamura


Evaluation of amyloidogenicities of human cystatins A, B and C using synthesized phenolic esters as prove.
PacifiChem 2010 2010
Author:Kensuke Morimoto, YukiMaeda, Shigeru Katayama, Soichiro Nakamura


Attenuated allergenicsymptoms by novel phenolic compounds prepared by enzymatic glycosylation with rutinase.
PacifiChem 2010 2010
Author:Yuki Yamauchi, Hiroshi Akiyama, Reiko Teshima, Shigeru Katayama, and Soichiro Nakamura


Immunomodulatory effect of yeast glucomannan on pollen allergy.
PacifiChem 2010 2010
Author:Takuya Kukita, Hiroshi Akiyama, Reiko Teshima, Shigeru Katayama, and Soichiro Nakamura


Ex-vivo and in vitro analyses using BIOPEP system to indentify early molecular targets for ACE inhibitory activity from soybean protein
153th Meeting ofChubu Branch in the Japan Society for Bioscience, Biotechnology, and Agrochemistry 2009, Nagoya, Japan 2009
Author:Matemu, A.O. and Nakamura, S.


Improving functional properties of tofuwhey-protein by lipophilization
Annual Meeting of Japan Society forBioscience, Biotechnology, and Agrochemistry 2009, Fukuoka, Japan 2009
Author:Matemu, A.O., Kayahara, H., Murasawa, H., Katayama,S. andNakamura, S.


Suppressive effect of blood free histidine on obesity
ACS 2009 Spring meeting 2009
Author:Nakajima, S., Iwai, H., Nakamura, S., Kasaoka, S., Ikeda, K., Amamiya, Y., Yamakura, F., Kawa, S., Katamoto, S.


Modulation of allergenicityof buckwheat Fag e 1 by Maillard-type glycosylation with polysaccharides.
ACS 2009 Spring meeting 2009
Author:Nakamura, S., Suzuki, Y. and Kassai, M.


Synthesis of functional phenolic compounds using rutinase from tartary buckwheat.
5th Pacific Rim Food Protein Symposium 2009
Author:Katayama, S. and Nakamura, S.


Oxidative stress-modulating effects of by-products and wastes from fruit and vegetable in chemical and cell culture systems.
5th Pacific Rim Food Protein Symposium 2009
Author:Tow, W-W. Katayama, S. and Nakamura, S.


Enhanced ACE inhibitory activity of tofu whey by enzymatic hydrolysis.
5th Pacific Rim Food Protein Symposium 2009
Author:Matemu, A.O., Katayama, S. and Nakamura, S.


Role of size and chargeof carbohydrate chains in surface functional properties of neoglycoproteins prepared from tofu whey.
5th Pacific Rim Food Protein Symposium 2009
Author:Matemu, A.O.,Katayama, S. and Nakamura, S.


Anti-hypertension effects of globulin peptides prepared from common oat (Avena sativa L.) and screening of globulin-rich species (Avena sp.).
5th Pacific Rim Food Protein Symposium 2009
Author:Nakamura, S., Kondo, H., Katayama, S., Kasuga, S., Shiba, T., Yamazaki, R. and Nakai, S.


Reduction of allergic response of buckwheat Fag e1 by Maillard-type glycosylation with food grade polysaccharides.
5th Pacific Rim Food Protein Symposium 2009
Author:Suzuki, Y., Kassai, M., Hirose, T., Katayama,S. and Nakamura, S.


Enzymatic synthesis of anti-amyloidal phenolic compounds.
5th Pacific Rim Food Protein Symposium 2009
Author:Kondo, H., Katayama,S. and Nakamura, S.


Ginsenosides show different behaviors in anti-amyloidogenicity between amyloid β-protein and human cystatin C.
5thPacific Rim Food Protein Symposium 2009
Author:Ogawa, H., Katayama, S. and Nakamura, S.


Role of regulatory T-cell and modulation of immunoresponse in BALB/c mice by oral administration of hypoallergenic allergen
5th Pacific Rim Food Protein Symposium 2009
Author:Soichiro Nakamura


Suppressive effect of histidine on energy intake -Results of nutrition survey in 2006-2008
9th Japan-Korea Joint Seminar on Fisheries Sciences 2009
Author:Shigeru Nakajima, Soichiro Nakamura, Bo-young Jeong, Soo-Kyung Moon, In-Soo Kim, Kyoung-Ae Lee, Hiroki Saeki


Influences of food habits and food preferences on histidine/protein intake -Results of survey both in Korea and Japan at 2006-2008
9th Japan-Korea Joint Seminar on Fisheries Sciences 2009
Author:Shigeru Nakajima, Soichiro Nakamura, Bo-young Jeong, Soo-Kyung Moon, In-Soo Kim, Kyoung-Ae Lee, Hiroki Saeki


Role of molecular surface properties of protein and carbohydrate toprepare surface functional neoglycoprotein with excellent emulsifying properties
Japan Society for Bioscience, Biotechnology, and Agrochemistry 2008, Nagoya, Japan 2008
Author:Matemu, A.O., Kayahara, H., Murasawa, H., and Nakamura, S.


Comparative studies on food intake and Nutrition between Japan and Korea.
8th Japan-Korea Joint Seminar on Fisheries Sciences 2008
Author:Nakajima, S., Nakamura, S., Saeki, S., Jeong, B-Y., Moon, S-K., Kim, I-S., Lee, K-A.


Present states and issues with regards to health and nutrition in Japan, the nation with the longest life expectancy
The 4th symposium for comparative studies on food intake and nutrition between Korea and Japan 2008
Author:Nakamura, S.


Food-grade phenolic compounds can modulate the amyloidgenicity of human cystatin C
14th World congress of Food Science&Technology (14th IUFoST) 2008
Author:Maeda, Y., Owaki, T. Nakamura, S.


Maillard-type glycosylation with polysaccharides can modulate the allergenicity of buckwheat Fag e 1
14th World congress of Food Science&Technology (14th IUFoST) 2008
Author:Nakamura, S., Suzuki, Y., Ishikawa, E. and Kassai, M.


Insights into the effects of Maillard-type glycosylation with water-soluble polysaccharides, e.g. arabinogalactan and xyloglucan, on the allergic immune response of a buckwheat globulin, Fag e 1
4th Symposium of the International Society of Rare Sugars 2008
Author:Nakamura, S., Suzuki,Y. and Kassai, M.


Improving emulsifying properties of Tofu whey by the Maillard-type conjugation with water soluble polysaccharides from soybean coat and Okara
Japan Society for Bioscience, Biotechnology, and Agrochemistry 2007, Tokyo, Japan 2007
Author:Matemu, A.O., Kayahara, H., Murasawa, H., and Nakamura, S.


Correlation between food habits and obesity in Korea and Japanese female students.
2nd Symposium for Comparative Studies on Food Intake and Nutrition between Japan and Korea 2007
Author:Moon,S-K., Kim, I-S., Jeong, B-Y., Lee, K-A., Nakamura,S., Watanabe, M., Ogawa, M. and Nakajima, S.


Suppressive effect of histidine on obesity effect of protein sufficient ratio and proline/protein intake.
7th Japan-Korea Joint Seminar on Fisheries Sciences 2007
Author:Moon, S-K., Lee, K-A., Kim, I-S., Jeong, B-Y., Saeki, H., Nakamura, S. and Nakajima, S.


Mechanism underlying the suppressive effect of dietary histidine on obesity.
7th Japan-Korea Joint Seminar on Fisheries Sciences 2007
Author:Nakajima, S., Kasaoka, S., Gotoh, K., Tanaka, K., Tsuchiya, T., Nakamura, S. and Saeki, H.


Report of the1st Symposium for Comparative Studies on Food Intake and Nutrition between Japan and Korea
7th Japan-Korea Joint Seminar on Fisheries Sciences 2007
Author:Nakamura, S., Nakajima, S. and Saeki, H.


Modulation of IgE production and Th1/Th2 cytokine response in Balb/c mice by glycosylated ovomucoid third domain
ICoFF2007 -International Conference on Food Factors for Health Promotion- 2007
Author:Prithy Rupa, Soichiro Nakamura, Yoshinori Mine


Glycosylated ovomucoid third domain can induce IgE-mediated allergic tolerance in Balb/c mice model
ICoFF2007 -International Conference on Food Factors for Health Promotion- 2007
Author:Mine, Y.,Silva, I., Rupa, P. and Nakamura, S.


Drastically reduced antigen-antibody interaction of Fag e 1 by the controlled Maillard-type glycosylation with polysaccharides
10th International Symposium on Buckwheat 2007
Author:Nakamura, S., Suzuki, Y., Ishikawa, E. and Jing, H.


Improper food habits will cause normal weight obesity.
6th Japan-Korea Joint Seminar on Fisheries Sciences 2006
Author:Nakajima, S ., Endo, M., Joeng, B-Y., Lee, K-A., Nakamura, S., and Saeki,H.


Changing food-preference of the young by idea-cooking of underutilizing fish
1st symposium for Comparative Studies on Food Intake and Nutrition between Japan and Korea 2006
Author:Nakamura, S. and Endo , M.


Improving functional properties of bioactive peptides derived from casein by the conjugation with carbohydrates and fattyacids
3rd Food Protein Symposium 2006
Author:Nakamura, S. and Kitts, D.D.


Bioactivities of gingseng extracts treated with recombinant Bifidobacterium β-glucosidase
96th Annual Meeting of American Oil Chemists Society (AOCS), Salt Lake City, Utah, USA 2005
Author:Nakamura, S., Jing, H., Endo, M., Shida, N., Iwai, H.


Enhancement of bioactivities of soy isoflavons and ginsenocides using recombinant β-D-glucosidase from Bifidobacteriumbreve
PacifiChem 2005, Honolulu, Hawaii, USA 2005
Author:Nakamura, S., Endo, M., Jing, H. and Kitts, D.D.


The site-directed glycosylation of human cystatin Cusing Pichia expression system improves its structural stability and antimicrobial activity
PacifiChem 2005, Honolulu, Hawaii, USA 2005
Author:Nakamura, S., Jing, H. and Kitts,D.D.


Suppressive effect of Histidine-rich protein intake on obesity
5th Japan-Korea Joint Seminar on Fisheries Science, Kunsan, Korea, JSPS/KOSEF 2005
Author:Nakajima, S ., Tsujii, M., Kasaoka, S., Inoue, S., Tsuchiya, T., Nakamura, S.


Improving bioactivities of soy isoflavons by deglycosyltion using recombinant ß-D-glucosidase from Bifidobacterium breve
95th AOCS Anual meeting, Cincinnati, USA 2004
Author:Nakamura, S., Iwai, H., Machida, K., Fukui, Y., Yamakura, F., and Sato, N.


Improving functional properties of caseinophosphopeptides by Maillard-type glycosylation with polysaccharides
20th World congress of international federation for home economics, Kyoto 2004
Author:Nakamura, S.


Comparison of fish composition tables between Japan and Korea
4th Japan-Korea Joint Seminar on Fisheries Science, Sapporo, Japan, JSPS/KOSEF 2004
Author:Nakamura, S., Endo, M., Jing, H., Suzuki, F., Nakajima, S., Saeki, H, Lee, Y-S., Lee, K-A., Moon, S-K., Kim,B-Y., Jeong, B-Y.,and Ann, D-H.


Molecularstability and bioactivity of genetically glycosylated human cystatin C in Pichiapastoris
2ndFood Protein Symposium. Food Scientists Network in Pacific Basin, Vancouver, Canada 2003
Author:Nakamura, S., Hata, J., Kawamukai, M., Matsuda, H., Nakamura, K., Ogawa, M., and Nakai, S.


Comparison of Pichia expression vectors; pGAP and pPCIZ, on the yield of recombinant human stefin A
2nd Food Protein Symposium. Food Scientists Network in Pacific Basin, Vancouver, Canada 2003
Author:Nakamura, S., Nakamura, K., Ogawa, M., and Nakai, S.


Suppressive Effect of histidine on food intake
2nd Food Protein Symposium. Food Scientists Network in Pacific Basin, Vancouver, Canada 2003
Author:Nakajima, S., Tsuji, M., Kasaoka, S., Inoue, S., Tsichiya, T., Iwai, H., Inaba, Y., and Nakamura, S.


Bioactivities of CPPI, CPPII, CPPIII, αCPP, βCPP and CGMP towards MC3T3-E1 and PC12 cell lines
2nd Food Protein Symposium. Food Scientists Network in Pacific Basin, Vancouver, Canada 2003
Author:Iwai, H., Kawaminami, K., Tsuchiya K., Kumaki, Y., Igai, J., Kitts, D.D., Nakajima, S., and Nakamura, S.


The present state and problem of Japanese dietary habits in terms of the relationship between histidine intake and BMI
3rd Japan-Korea Joint Seminar on Fisheries Sciences Jinju-Tongyeong, Korea, JSPS/KOSEF 2003
Author:Nakamura, S., Nakajima, S. Tsuji, M., Endo,M., and Saeki, H.


Antioxidant properties of caseinophosphopeptides
222nd ACS National Meeting, Chikago, USA 2001
Author:Shelia C. K., Nakamura, S., and Kitts, D.D.


Enhancement of proteinase inhibitoru activity of recombinant human cystatin C using randam-centroid optimization
14th Annual JR Brunner Protein Symposium , Michigan State University (ACS), USA 2001
Author:Ogawa, M., Nakamura, S., Scaman, C.H., Jing, H., Kitts, D.D., Dou, J., Nakai, S.


Improved functional properties of carp myofibrillar protein by conjugation with alginateoligosaccharide
PacifiChem2000 American ChemicalSociety (Hawaii, USA) 2000
Author:Sato R., Sawabe T.,Nakamura S., and Saeki H.


Thermostability improvement of human cystatin C using site-directed mutagenesis directed by randam-centroid optimization for genetics
PacifiChem2000 American Chemical Society (Hawaii, USA) 2000
Author:Ogawa M., Nakamura S., Scaman C., and Nakai S:


Oligoglycosylation of lysozyme by chemical and genetic modifications
PacifiChem2000 American Chemical Society (Hawaii, USA) 2000
Author:Nakamura S., Miyasaka S., Saito M., Goto T., Saeki H., Ogawa M., and Kato A.


Molecular design of cystatin by genetic glycosylation for food ingredient
PacifiChem2000 American Chemical Society (Hawaii, USA) 2000
Author:Nakamura S., Hata J., Ogawa M., Saito M., Saeki H., and Nakai S.


Production of genetically modified human cystatin C by Pichia pastoris
54th ACS Northwest regional meeting, Oregon, USA 1999
Author:Ogawa, M., Nakamura, S., Nakai, S., and Scaman, C.


Structural changes in fish actomyosin during setting
1st Food Protein Symposium. Food Scientists Network in Pacific Basin, Vancouver, Canada 1999
Author:Ogawa, M., Nakamura, S., Horimoto, Y., An, H., Tsuchiya, T., and Nakai, S.


Antimicrobial effect of achacin expressed in yeast
1st Food Protein Symposium. Food Scientists Network in Pacific Basin, Vancouver, Canada 1999
Author:Ogawa, M., Nakamura, S., Atsuchi, T., Tamiya, T., Tsuchiya, T., and Nakai, S.


Application of recombinant polymannosyl cystatin C to seafood processing
1st Food Protein Symposium. Food Scientists Network in Pacific Basin, Vancouver, Canada 1999
Author:Nakamura, S., Ogawa, M., Saito, M., Scaman, C., and Nakai, S.


pH regulation affects the glycosylation of mutant lysozyme having the N-linked signalsequence in yeast
1st Food Protein Symposium. Food Scientists Network in PacificBasin, Vancouver, Canada, 1999
Author:Nakamura, S., Ban, M., and Kato, A.


Characterization of bacteria contaminating foods using GC/PCS analysis
1st Food Protein Symposium. Food Scientists Networkin Pacific Basin, Vancouver, Canada 1999
Author:Nakai, S., Dou, J., Nakamura, S., Ogawa, M., Ogihara, H., and Skura, B.


Production of genetically modified human cystatinC by Pichia pastoris
54th ACS Northwest regional meeting, American Chemical Society, Oregon, USA 1999
Author:Ogawa, M., Nakamura, S., Nakai, S., and Scaman, C.


Structural changes in fish actomyosin during setting
1st Food Protein Symposium. Food Scientists Network in Pacific Basin (Vancouver, Canada) 1999
Author:Ogawa, M., Nakamura, S., Horimoto, Y., An, H., Tsuchiya, T., and Nakai, S.


Antimicrobial effect of achacinexpressed in yeast.
1st Food Protein Symposium. Food Scientists Network in Pacific Basin (Vancouver, Canada) 1999
Author:Ogawa, M., Nakamura, S., Atsuchi, T., Tamiya, T., Tsuchiya, T., and Nakai, S.


Application of recombinant polymannosyl cystatin C to seafood processing
1st Food Protein Symposium. Food Scientists Network in Pacific Basin (Vancouver, Canada) 1999
Author:Nakamura, S., Ogawa, M., Saito, M., Scaman, C., and Nakai, S.


pH regulation affects the glycosylation of mutant lysozyme having the N-linked signal sequence in yeast
1st Food Protein Symposium. Food Scientists Network in Pacific Basin (Vancouver, Canada) 1999
Author:Nakamura, S., Ban, M., and Kato, A.


Characterization of bacterial contaminateding foods using GC/PCS analysis
1st Food Protein Symposium. FoodScientists Network in Pacific Basin (Vancouver, Canada) 1999
Author:Nakai, S., Dou, J., Nakamura, S., Ogawa, M., Ogihara, H., and Skura, B.


Production of genetically modified human cystatin C by Pichia pastoris.
54th ACS Northwest regional meeting, American Chemical Society (Oregon, USA) 1999
Author:Ogawa, M., Nakamura, S., Nakai, S., and Scaman, C.


GC/PCS system for detection of E. coli and S. aureus contaminating salmon and hamburger
1998 IFT Annual Meeting, Atlanta, USA 1998
Author:Nakai, S., Wang, Z.H., Dou, J., Nakamura, S., Ogawa, M., Nakai, E., and Vanderstoep, J.


Production of a recombinant glycoprotein, achacin, to use as a food preservative
1998 IFT Annual Meeting, Atlanta, USA 1998
Author:Ogawa, M., Nakamura, S., Atsuchi, T., Tamiya, T., Tsuchiya, T., and Nakai, S.


Production of cysteine protease inhibitor cystatin C in Pichia pastoris and its application to seafood processing
1998 IFT Annual Meeting, Atlanta, USA 1998
Author:Nakamura, S., Ogawa, M., Scaman, C., and Nakai, S.


A graphic solution of global optimization for applying to site-directed mutagenesis
1997 IFT Annual Meeting, Orlando, USA 1997
Author:Nakai, S., Nakamura,S., and Vanderstoep, J.


Production of genetically modified lysozyme having extreme heat stability and antimicrobial activity against Gram negative bacteria in yeast and in plant
5th Symposium on Food Proteins -Structural and Functional Aspects of Food Protein Modification, Potsdom, Germany 1997
Author:Kato, A., Nakamura, S., Ibrahim, H., and Kato, M.


Engineering of the helix active site of Bacillus stearothermophilus neutral protease -An attempt to create novel protease with alternative activities
5th Symposium on Food Proteins -Structural and Functional Aspects of Food Protein Modification, Potsdom, Germany 1997
Author:Nakamura, S. and Nakai, S.


Computer-aided optimization of site-directed mutagenesis of food ingredients
5th Chemical Congress of North America, Cancun, Mexico 1997
Author:Nakai, S., Nakamura, S., and Scaman, C.


Improving thermostability of Bacillus stearothermophilus neutral protease using computer-aided optimization
1996 IFT Annual Meeting, New Orleans, USA 1996
Author:Nakamura, S. and Nakai, S.


Expression of lysozyme in Bacillus subtilis: Role of pro-region of neutral protease from Bacillus stearothermophilus
1997 IFT Annual Meeting, Orlando, USA 1996
Author:Nakamura, S., Ogawa, M., Saito, M., and Nakai, S.


Expression of papain in Bacillus subtilis using pre-pro region of Bacillus stearothermophilus neutral protease
1995 IFT Annual Meeting, Anaheim, USA 1995
Author:Dhanawansa, U.H., Nakamura, S.and Nakai, S.1995


Protein engineering of Bacillus stearothermophilus neutral protease having alternative enzymatic activities
1995 IFT Annual Meeting, Anaheim, USA 1995
Author:Nakamura, S, Dhanawansa, U.H., Dhanawansa, G.L.R., and Nakai, S.


Novel functional properties of glycosylated lysozymes constructed by genetic engineering
PacifiChem 1995American Chemical Society, Honolulu, USA 1995
Author:Kato, A. and Nakamura, S.


Thermostable Bacillus stearothermophilus neutral protease with carbohydrate chain
PacifiChem 1995 American Chemical Society, Honolulu, USA 1995
Author:Nakamura, S. and Nakai, S.


その他
Working together for sustainable agriculture
Mae Fah Luang University, Thailand 2014(Apr. 25)
Author:Soichiro Nakamura


Working together for agriinovations designed with sustainable agriculture
Dalian University, China , Keynote Address at the International Conference on "Exploitation and prospect of functional biology resources" 2013(Nov. 29)
Author:Soichiro Nakamura


Working together for agro-innovations designed with the construction of global eco-friendly agricultural system.
Zhejiang Academy of Agricultural Sciences (ZAAS), Zhejiang, China , Memorial lecture for establishment of international academic cooperation relationship betweenZAAS and Shinshu University 2012(Sep. 12)
Author:Soichiro Nakamura

特許等知的財産
登録済特許
アミロイド形成阻害剤の製造方法
Hsp発現促進剤
花粉症症状軽減作用を有するキクイモの抽出物
老化に伴う身体的症状の発現遅延剤
共同研究等希望テーマ
アレルギー改善機能をもつ食素材の開発
認知症を含むアミロイドーシス予防抑制機能をもつ食素材の開発
ノロウィルス感染を含むウィルス性食中毒予防抑制機能をもつ食素材の開発
肥満や高血圧症予防抑制機能をもつ食素材の開発
その他,分子表面機能特性に優れた食素材の開発
研究費
共同研究
2005 - , 朝鮮人参由来のメタボリックシンドローム予防治療効果成分の探索とそれらの機能改善 , 国際共同研究
2005 - , バイオマスの高度有効利用に関する研究 , 国際共同研究
2005 - , 食品由来ACE阻害成分の探索とそれらの機能改善 , 国際共同研究
2005 - , 食品アレルギーの戦略的低減化に関する国際共同研究 , 国際共同研究

科学研究費補助金(研究代表者)
2014 - 2016 , 量子ドットプローブを用いたフェニルプロパノイド系抗アミロイド性新素材の分子設計 , 基盤研究(C)
2011 - 2013 , アミロイド性蛋白質を用いた抗アミロイドーシス性カテコール誘導体の分子モデリング , 基盤研究(C)
2008 - 2010 , アミロイド型蛋白質を用いた抗コンフォメーション病食品素材の分子モデリング , 基盤研究(C)
2006 - 2008 , モデル蛋白質を用いた食原性プリオン伝播抑制効果を持つ食品成分の探索とその機能改良 , 基盤研究(C)
2004 - 2006 , オリゴマンノシル化シスタチンの癌,ウィルスおよび寄生虫ストレスモジュレータ機能 , 外国人特別研究員奨励費
1999 - 2000 , 食品タンパク質の多糖修飾による安全な抗菌・抗ウィルス性食品素材の開発 , 科研(C)

科学研究費補助金(研究分担者)
2016 - 2019 , 量子ドットナノプローブを活用したアミロイド凝集阻害物質の探索とその作用機序の解明 , 基盤研究(B)
2000 - 2001 , アルギン酸オリゴ糖修飾による魚類筋原線維タンパク質の機能改変 , 科研(C)
1999 - 2000 , 生物環境モニターとしての貝類におけるトリクロロ酢酸の蓄積に関する研究 , 科研(C)

その他公的資金
2010 - 2010 , 「水溶性バイオマス多糖由来エタノール生産システムの開発」独立行政法人科学技術振興機構,平成21年度地域イノベーション創出総合支援事業「シーズ発掘試験」
2008 - 2008 , 「蕎麦のアレルギー性低減化への国産カラマツ由来水溶性多糖の応用」(財)長野県テクノ財団,平成19年度地域産学官共同研究活性化(財団版RSP)事業
2007 - 2007 , 「雑穀由来抗高血圧症食品素材の開発と応用」独立行政法人科学技術振興機構,平成18年度地域イノベーション創出総合支援事業「シーズ発掘試験」
2005 - 2005 , 「雲州高麗人参の高度利用,高付加価値化に関する研究」(財)しまね産業振興財団,平成16年度しまね産官学協働推進事業可能性試験
2002 - 2004 , Characterization and evaluation of bioactive peptides derivedfrom casein as potential modulator of immune activity: Natural Sciences and Engineering Research Council of Canada (NSERC)
2001 - 2002 , The study of Dairy Proteins as natural antioxidants and modulators of oxidative stress: Dairy Farmers of Canada

教育活動実績

研究員受入
2004-2006 , Hao Jing (University of British Columbia): オリゴマンノシル化シスタチンの癌、ウィルスおよび寄生虫ストレスモジュレータ機能
2003-2003 , Peter Wong (University of British Columbia):リポフィル化ミルクカゼインの抗菌・抗ウィルス性に関する研究
2000-2002 , Shiela Chiu (University of British Columbia): 多糖修飾によるミルクカゼインの機能改変