平塚 佐千枝 (ヒラツカ サチエ)
学術研究院（医学系）
先鋭領域融合研究群 バイオメディカル研究所
教授
研究者情報
研究キーワード
- 癌, 転移
メールアドレス
- hira★shinshu-u.ac.jp
経歴
研究活動情報
論文
- Suppression of CEBPδ recovers exhaustion in anti-metastatic immune cells.
Yin C, Kato M, Tomita T, Han Y Hiratsuka S
Scientific Reports, 13(3903), 2023年 - Citrullinated fibrinogen-SAAs complex causes vascular metastagenesis
Han Y, Tomita T, Kato M, Ashihara N, Higuchi Y, Matoba H, Wang W, Hayashi H, Itoh Y, Takahashi S, Kurita H, Nakayama J, Okumura N, Hiratsuka S
NATURE COMMUNICATIONS, 14(4960), 2023年 - Extracellular mRNA transported to the nucleus exerts translation-independent function.
Tomita T, Kato M, Mishima T, Matsunaga Y, Sanjo H, Ito, K, Minagawa K, Matsui T, Oikawa H, Takahashi S, Takao T, Iwai N, Mino T, Takeuchi O, Maru Y, Hiratsuka S
NATURE COMMUNICATIONS, 12, 2021年
責任著者 - Regulation of vascular permeability in cancer metastasis
Tomita T, Kato M, Hiratsuka S
Cancer Science,, 2021年
責任著者
- Hepato-entrained B220+CD11c+NK1.1+ cells regulate pre-metastatic niche formation in the lung.
Hiratsuka S., Tomita T., Mishima T., Matsunaga Y., Omori T., Ishibashi S., Yamaguchi S., Hosogane T., Watarai H., Omori-Miyake M., Yamamoto T., Shibata N., Watanabe A., Aburatani H., Tomura M., High. KA., Maru Y.
EMBO Mol. Med, (e8643), 2018年 - Pre-metastatic niches: organ-specific homes for metastases
David Lyden, Hector Peinado, Haiying Zhang, Irina Matei, Bruno Costa-Silva, Hoshino Ayuko, Goncalo Rodrigues, Bethan Psaila, Rosandra Kaplan, Jacqueline Bromberg, Yibin Kang, Mina Bissell, Thomas Cox, Amato Giaccia, Janine Erler, Sachie Hiratsuka, and Cyrus Ghajar
Nature Reviews Cancer, (17), 302-317, 2017年 - Primary tumours modulate innate immune signalling to create pre-metastatic vascular hyperpermeability foci.
Hiratsuka S., Ishibashi S., Tomita T., Watanabe A., Akashi-Takamura S., Murakami M., Kijima H., Miyake K., Aburatani H., Maru
Nature Communications, 4(1853), 2013年 - Endothelial focal adhesion kinase mediates cancer cell homing to discrete regions of the lungs via E-selectin up-regulation.
Hiratsuka S, Goel S, Kamoun WS, Maru Y, Fukumura D, Duda DG, Jain RK
Proc Natl Acad Sci U S A, (108), 3725-3730, 2011年 - C-X-C receptor type 4 promotes metastasis by activating p38 mitogen-activated protein kinase in myeloid differentiation antigen (Gr-1)-positive cells.
Hiratsuka S, Duda DG, Huang Y, Goel S, Sugiyama T, Nagasawa T, Fukumura D, Jain RK.
Proc Natl Acad Sci U S A, (108), 302-307, 2011年 - The S100A8-serum amyloid A3-TLR4 paracrine cascade establishes a pre-metastatic phase.
Hiratsuka S, Watanabe A, Sakurai Y, Akashi-Takamura S, Ishibashi S, Miyake K, Shibuya M, Akira S, Aburatani H, Maru Y
Nat. Cell Biol., (10), 1349-1355, 2008年 - Tumor-mediated upregulation of chemoattractants and recruitment of myeloid cells pre-determines lung metastasis.
Hiratsuka S, Watanabe A, Aburatani H, Maru Y.
Nat. Cell Biol., (8), 1369-1375, 2006年 - Involvement of MMP9 induction by Vascular Endothelial Growth Factor Receptor-1 in lung specific metastasis
Hiratsuka S, Nakamura K, Iwai S, Murakami M, Itoh T, Kijima H, Shipley JM, Senior RM, Shibuya M.
CANCER CELL, 2, 289-300, 2002年
筆頭著者
