2015 , 酵素工学奨励賞 , 「配列パターンデザインによる新規人工設計タンパク質の半合理的創製と構造解析およびナノ構造構築への応用」 2013 , 第13回リバネス研究費Direct Detect賞 2011 , PDB40 Travel Award , Protein Data Bank 40th Anniversary Symposium 2011 , Protein Science Young Investigator Travel Grant / The Protein Society Finn Wold Travel Award , IX European Symposium of The Protein Society 2001 , 平成12年度石井学術奨励賞 1996 , 平成8年度化学工学会関東支部長賞(学生賞)
留学歴 2019-2019 , 米国ワシントン大学タンパク質デザイン研究所 David Baker Lab, Visiting scholar 2006-2007 , 米国プリンストン大学化学科 Michael H Hecht Lab (学振海外特別研究員)
研究活動業績
研究業績(著書・ 発表論文等)
書籍等出版物 Linkers in Biomacromolecules Chapter 8 "Design of helical linkers for fusion proteins and protein-based nanostructures", Methods in Enzymology 647 , 209-230 Elsevier 2021 Author:Ryoichi Arai
Characterization of underwater silk proteins from caddisfly larva, Stenopsyche marmorata, Biotechnology of Silk: Biologically inspired systems Volume 5 , Ch. 6, pp. 107-122 Springer, New York 2013 Author:Ohkawa, K., Nomura, T., Arai, R., Hirabayashi, K., Tsukada, M., and Abe , K.
論文 Reversible Assembly of an Artificial Protein Nanocage Using Alkaline Earth Metal Ions JOURNAL OF THE AMERICAN CHEMICAL SOCIETY,145(1):216-223 2023 Author:Ohara, Naoya; Kawakami, Norifumi; Arai, Ryoichi; Adachi, Naruhiko; Moriya, Toshio; Kawasaki, Masato; Miyamoto, Kenji;
Production of pentaglycine-fused proteins using Escherichia coli expression system without in vitro peptidase treatment PROTEIN EXPRESSION AND PURIFICATION,194:106068 2022(Jun.) Author:Sakono, Masafumi; Oshima, Tatsuki; Iwakawa, Takako; Arai, Ryoichi; Keywords:Methionyl aminopeptidase; Peptide ligation; Polyglycine; Protein expression; Sortase A;
Self-Assembling Lectin Nano-Block Oligomers Enhance Binding Avidity to Glycans International Journal of Molecular Sciences,23(2):676 2022(Jan.) Author:Shin Irumagawa, Keiko Hiemori, Sayoko Saito, Hiroaki Tateno, Ryoichi Arai
Icosahedral 60-meric porous structure of designed supramolecular protein nanoparticle TIP60 Chemical Communications,57(79):10226-10229 2021(Sep.) Author:Junya Obata, Norifumi Kawakami, Akihisa Tsutsumi, Erika Nasu, Kenji Miyamoto, Masahide Kikkawa, Ryoichi Arai
Rational thermostabilisation of four-helix bundle dimeric de novo proteins Scientific Reports,11:7526 2021(Apr. 06) Author:Shin Irumagawa, Kaito Kobayashi, Yutaka Saito, Takeshi Miyata, Mitsuo Umetsu, Tomoshi Kameda & Ryoichi Arai
Hyperstable De Novo Protein with a Dimeric Bisecting Topology ACS Synthetic Biology,9(2):254-259 2020 Author:Kimura, N., Mochizuki, K., Umezawa K., Hecht, M.H., Arai, R.
Design of hollow protein nanoparticles with modifiable interior and exterior surfaces Angewandte Chemie International Edition,57:12400-12404 2018 Author:Norifumi Kawakami, Hiroki Kondo, Yuki Matsuzawa, Kaoru Hayasaka, Erika Nasu, Kenji Sasahara, Ryoichi Arai, Kenji Miyamoto
Self-assembling supramolecular nanostructures constructed from de novo extender protein nanobuilding blocks ACS Synthetic Biology,7(5):1381-1394 2018 Author:Naoya Kobayashi, Kouichi Inano, Kenji Sasahara, Takaaki Sato, Keisuke Miyazawa, Takeshi Fukuma, Michael H Hecht, Chihong Song, Kazuyoshi Murata, and Ryoichi Arai
Hierarchical design of artificial proteins and complexes toward synthetic structural biology Biophysical Reviews,10:391-410 2018 Author:Arai, R.
Comparative analysis of plant isochorismate synthases reveals structural mechanisms underlying their distinct biochemical properties Bioscience Reports,38:BSR20171457 2018 Author:2. Yokoo, S., Inoue, S., Suzuki, N., Amakawa, N., Matsui, H., Nakagami, H., Takahashi, A., Arai R. and Katou, S.
Design and construction of self-assembling supramolecular protein complexes using artificial and fusion proteins as nanoscale building blocks Current Opinion in Biotechnology,46:57–65 2017 Author:Kobayashi, N. and Arai, R.
Flight density of the aquatic insect fauna over the water surface in the middle reaches of the Shinano River, Japan, mainly among caddisflies (Trichoptera) Zoosymposia,10:203–213 2016 Author:Hirabayashi, K.*, Ikutama, E., Ohkawa, K., Arai, R., Nomura, T., Tsukada, M., and Abe, K.
Characterization of silk gland ribosomes from a bivoltine caddisfly, Stenopsyche marmorata: translational suppression of a silk protein in cold conditions. Biochemical and Biophysical Research Communications,469:210-215 2016 Author:Takaomi Nomura, Miho Ito, Mai Kanamori, Yuta Shigeno, Toshio Uchiumi, Ryoichi Arai, Masuhiro Tsukada, Kimio Hirabayashi, Kousaku Ohkawa
Expression, purification, crystallization and X-ray diffraction analysis of ChiL, a chitinase from Chitiniphilus shinanonensis Acta Cryst. F,F71(12):1516–1520 2015(Dec.) Author:Miruku Ueda, Makoto Shimosaka and Ryoichi Arai
Molecular cloning, gene expression analysis, and recombinant protein expression of novel silk proteins from larvae of a retreat-maker caddisfly, Stenopsyche marmorata Biochem. Biophys. Res. Commun.,464(3):814–819 2015 Author:Xue Bai, Mayo Sakaguchi, Yuko Yamaguchi, Shiori Ishihara, Masuhiro Tsukada, Kimio Hirabayashi, Kousaku Ohkawa, Takaomi Nomura, Ryoichi Arai
Self-Assembling Nano-Architectures Created from a Protein Nano-Building Block Using an Intermolecularly Folded Dimeric De Novo Protein J. Am. Chem. Soc.,137(35):11285–11293 2015 Author:Naoya Kobayashi, Keiichi Yanase, Takaaki Sato, Satoru Unzai, Michael H. Hecht, Ryoichi Arai
Crystal structure of ChiL, a chitinase from Chitiniphilus shinanonensis Photon Factory Activity Report 2014,32(B):206 2015 Author:Ueda, M., Shimosaka, M., and Arai, R.
Crystal structure of Fab fragment of an anti-Osteocalcin C-Terminal peptide antibody KTM219 Photon Factory Activity Report 2014,32(B):205 2015 Author:Komatsu, M., Dong, J., Ueda, H., and Arai, R.
Crystal structure of glycine oxidase from Geobacillus kaustophilus Photon Factory Activity Report 2014,32(B):204 2015 Author:Shiono, T., Nomura, T., Nishiya, Y., and Arai, R.
Intermolecular interactions and molecular dynamics in bovine serum albumin solutions studied by small angle X-ray scattering and dielectric relaxation spectroscopy. J. Mol. Liq.,200(A):59-66 2014 Author:Yanase, K., Arai R., and Sato, T.
Functional characterization of FABP3, 5 and 7 gene variants identified in schizophrenia and autism spectrum disorder and mouse behavioral studies. Hum. Mol. Genet.,23:6495-6511 2014 Author:Shimamoto C, Ohnishi T, Maekawa M, Watanabe A, Ohba H, Arai R, Iwayama Y, Hisano Y, Toyota T, Toyoshima M, Suzuki K, Shirayama Y, Nakamura K, Mori N, Owada, Y, Kobayashi T, and Yoshikawa T
Crystal structure of glycine oxidase from Bacillus thuringiensis Photon Factory Activity Report 2013,31(B):274 2014 Author:Ohishi, S., Shiono, T., Nishiya, Y., Nomura, T., and Arai, R.
Chain conformational study on underwater silk protein from caddisfly, Stenopsyche marmorata: Implication of a fiber-forming mechanism Adv. Mater. Res.,796:41706 2013 Author:Ohkawa, K., Hachisu, M., Nomura, T., Arai, R., Hirabayashi, K., Tsukada, M., and Abe, K
Long-range periodic sequence of Stenopsyche marmorata cement/silk protein: Purification and biochemical characterization Biofouling,29(4):357-367 2013 Author:Ohkawa, K., Miura, Y., Nomura, T., Arai, R., Abe, K., Tsukada M. and Hirabayashi, K.
Isolation of silk proteins from a caddisfly larva, Stenopsyche marmorata. J. Fiber Bioeng. Informatics,5:125-137 2012 Author:Ohkawa, K., Miura, Y., Nomura, T., Arai, R., Abe, K., Tsukada M. and Hirabayashi, K.
Solution structure of IseA, an inhibitor protein of DL-endopeptidases from Bacillus subtilis, reveals a novel fold with a characteristic inhibitory loop J. Biol. Chem.,287(53):44736-44748 2012 Author:Arai, R., Fukui, S., Kobayashi, N. and Sekiguchi, J. Abstract:解説は信州大学のプレリリースサイトへ http://www.shinshu-u.ac.jp/faculty/textiles/news/2012/12/50284.html
Domain-Swapped Dimeric Structure of a Stable and Functional De Novo 4-Helix Bundle Protein, WA20 J. Phys. Chem. B,116(23):6789-6797 2012 Author:Arai, R., Kobayashi, N., Kimura, A., Sato, T., Matsuo, K., Wang, A.F., Platt, J.M., Bradley, L.H., Hecht, M.H. Abstract:解説は信州大学のプレリリースサイトへ http://www.shinshu-u.ac.jp/faculty/textiles/news/2012/03/46854.html
Crystal structure of a menaquinone biosynthetic enzyme, TthMqnD, complexed with its product, 1,4-dihydroxy-6-naphthoate Photon Factory Activity Report 2010,28:B298 2011 Author:Matsuo, K., Dairi, T., Seto, H. and Arai, R.
Crystal structure of a dimeric de novo 4-helix bundle protein, WA20 Photon Factory Activity Report 2010,28:B256 2011 Author:Arai, R., Kobayashi, N., Kimura, A., Sato, T., Wang, A.F., Platt, J.M., Bradley, L.H. and Hecht, M.H.
Dissecting cell signaling pathways with genetically encoded 3-iodo-L-tyrosine ChemBioChem,12:387-389 2011 Author:Hayashi A, Hino N, Kobayashi T, Arai R, Shirouzu M, Yokoyama S, Sakamoto K.
Polymorphism screening of brain-expressed FABP7, 5 and 3 genes and association studies in autism and schizophrenia in Japanese subjects J. Hum. Genet.,55:127-130 2010 Author:Maekawa, M.,Iwayama, Y., Arai, R., Nakamura, K., Ohnishi, T., Toyota, T., Tsujii, M., Okazaki, Y., Osumi, N., Owada, Y., Mori, N., and Yoshikawa, T.
Crystal structure of MqnD (TTHA1568), a menaquinone biosynthetic enzyme from Thermus thermophilus HB8 J. Struct. Biol,168:575-581 2009 Author:Arai, R., Murayama, K., Uchikubo-Kamo, T., Nishimoto, M., Toyama, M., Kuramitsu, S., Terada, T., Shirouzu, M. and Yokoyama, S.
Fabp7 Maps to a Quantitative Trait Locus for a Schizophrenia Endophenotype PLoS Biol.,5:e297 2007 Author:Watanabe, A., Toyota, T., Owada, Y., Hayashi, T., Iwayama, Y., Matsumata, M., Ishitsuka, Y., Nakaya, A., Maekawa, M., Ohnishi, T., Arai, R., Sakurai, K., Yamada, K., Kondo, H., Hashimoto, K., Osumi, N. and Yoshikawa T.
Crystal structure of human myo-inositol monophosphatase 2, the product of the putative susceptibility gene for bipolar disorder, schizophrenia, and febrile seizures Proteins,67:732-742 2007 Author:Arai, R.,* Ito, K.,* Ohnishi, T., Ohba, H., Akasaka, R., Bessho, Y., Hanawa-Suetsugu, K., Yoshikawa, T., Shirouzu, M. and Yokoyama, S.
Structure of archaeal glyoxylate reductase from Pyrococcus horikoshii OT3 complexed with nicotinamide adenine dinucleotide phosphate Acta Crystallogr. D,63:357-365 2007 Author:Yoshikawa, S.,* Arai, R.,* Kinoshita, Y., Uchikubo-Kamo, T., Wakamatsu, T., Akasaka, R., Masui, R., Terada, T., Kuramitsu, S., Shirouzu, M. and Yokoyama, S. (*The authors contributed equally to the work.)
Crystal structure of the conserved protein TTHA0727 from Thermus thermophilus HB8 at 1.9 A resolution: A CMD family member distinct from carboxymuconolactone decarboxylase (CMD) and AhpD Protein Sci.,15:1187-1192 2006 Author:Ito, K.,* Arai, R.,* Fusatomi, E., Kamo-Uchikubo, T., Kawaguchi, S., Akasaka, R., Terada, T., Kuramitsu, S., Shirouzu, M. and Yokoyama, S.
Structure of human ubiquitin-conjugating enzyme E2 G2 (UBE2G2/UBC7) Acta Crystallogr. F,62:330-334 2006 Author:Arai, R.,* Yoshikawa, S.,* Murayama, K., Imai, Y., Takahashi, R., Shirouzu, M. and Yokoyama, S.
Crystal structure of the probable haloacid dehalogenase PH0459 from Pyrococcus horikoshii OT3 Protein Sci.,15:373-377 2006 Author:Arai, R., Kukimoto-Niino, M., Kuroishi, C., Bessho, Y., Shirouzu, M. and Yokoyama, S.
Crystal structure of an enhancerof rudimentary homolog (ERH) at 2.1 Angstroms resolution Protein Sci.,14:1888-1893 2005 Author:Arai, R., Kukimoto-Niino, M., Uda-Tochio, H., Morita, S., Uchikubo-Kamo, T., Akasaka, R., Etou, Y., Hayashizaki, Y., Kigawa, T., Terada, T., Shirouzu, M. and Yokoyama, S.
Conserved protein TTHA1554 from Thermus thermophilus HB8 binds to glutamine synthetase and cystathionine beta-lyase Biochim. Biophys. Acta,1750:40-47 2005 Author:Arai, R.,* Nishimoto, M.,* Toyama, M., Terada, T., Kuramitsu, S., Shirouzu, M. and Yokoyama, S. Conserved protein TTHA1554 from Thermus thermophilus HB8 binds to glutamine synthetase and cystathionine beta-lyase
Establishment of stable hFis1 knockdown cells with an siRNA expression vector J. Biochem.,136:421-425 2004 Author:Arai, R.,* Ito,K.,* Wakiyama, M., Matsumoto, E., Sakamoto, A., Etou, Y., Otsuki, M., Inoue, M., Hayashizaki, Y., Miyagishi, M., Taira, K., Shirouzu, M. and Yokoyama, S.
Phosphorylation analysis of 90 kDa heat shock protein within the cytosolic arylhydrocarbon receptor complex Biochemistry,43:15510-15519 2004 Author:Ogiso, H., Kagi, N., Matsumoto, E., Nishimoto, M., Arai, R., Shirouzu, M., Mimura, J., Fujii-Kuriyama, Y. and Yokoyama, S.
Conformations of variably linked chimeric proteins evaluated by synchrotron X-ray small-angle scattering Proteins,57:829-838 2004 Author:Arai, R., Wriggers, W., Nishikawa, Y., Nagamune, T. and Fujisawa, T.
An optimized homogeneous noncompetitive immunoassay based on the antigen-driven enzymatic complementation J. Immunol. Methods,279:209-218 2003 Author:Ueda, H., Yokozeki, T., Arai, R., Tsumoto, K., Kumagai, I. and Nagamune, T.
A homogeneous noncompetitive immunoassay for the detection of small haptens Anal. Chem.,74:2500-2504 2002 Author:Yokozeki, T., Ueda, H., Arai, R., Mahoney, W. and Nagamune, T.
A homogeneous and noncompetitive immunoassay based on the enhanced fluorescence resonance energy transfer by leucine zipper interaction Anal. Chem.,74:5786-5792 2002 Author:Ohiro, Y., Arai, R., Ueda, H. and Nagamune, T.
Detection of protein-protein interaction by bioluminescence resonance energy transfer from firefly luciferase to red fluorescent protein J. Biosci. Bioeng.,94:362-364 2002 Author:Arai, R., Nakagawa, H., Kitayama, A., Ueda, H. and Nagamune, T
Demonstration of a homogeneous noncompetitive immunoassay based on bioluminescence resonance energy transfer Anal. Biochem.,289:77-81 2001 Author:Arai, R., Nakagawa, H., Tsumoto, K., Mahoney, W., Kumagai, I., Ueda, H. and Nagamune, T.
Design of the linkers which effectively separate domains of a bifunctional fusion protein Protein Eng.,14:529-532 2001 Author:Arai, R., Ueda, H., Kitayama, A., Kamiya, N. and Nagamune, T.
Construction of green fluorescent protein reporter genes for genotoxicity test (SOS/umu-Test) and improvement of mutagen-sensitivity J. Biosci. Bioeng,92:301-304 2001 Author:Arai, R., Makita, Y., Oda, Y. and Nagamune, T.
Design of an artificial light-harvesting unit by protein engineering: Cytochrome b(562)-green fluorescent protein chimera Biochem. Biophys. Res. Commun.,289:299-304 2001 Author:Takeda, S., Kamiya, N., Arai, R. and Nagamune, T.
Fluorolabeling of antibody variable domains with green fluorescent protein variants: application to an energy transfer-based homogeneous immunoassay Protein Eng.,13:369-376 2000 Author:Arai, R., Ueda, H., Tsumoto, K., Mahoney, W.C., Kumagai, I. and Nagamune, T.
Construction of chimeric proteins between protein G and fluorescence-enhanced green fluorescent protein, and their application to immunoassays J. Ferment. Bioeng.,86:440-445 1998 Author:Arai, R., Ueda, H. and Nagamune, T.
講演・口頭発表等 Molecular cloning of novel silk proteins from larvae of caddisfly, Stenopsyche marmorata 8th Chaina International Silk Conference 2013 2013 Presenter:K. Ohkawa, M. Hachisu, T.Nomura, R.Arai, K. Hirabayashi, M. Tsukada and K. Abe
Molecular cloning of novel silk proteins from larvae of caddisfly, Stenopsyche marmorata Young Researcher Symposium 2013 2013 Presenter:X.Bai, K.Ohkawa, T.Nomura, S.Ishihara, Y.Yamaguchi, M.Tsukada, K.Abe, K.Hirabayashi, R. Arai
Construction and characterization of tandem WA20 domain-swapped de novo proteins with various linkers. 27th Annual Symposium of The Protein Society. 2013 Presenter:Naoya Kobayashi, N., Michael H. Hecht, and Ryoichi Arai
Biochemical natures of underwater silk proteins from caddisfly, Stenopsyche marmorata The international Textile Conference 2013 2013 Presenter:Kousaku Ohkawa, Masakazu Hachisu, Takaomi Nomura, Ryoichi Arai, Masuhiro Tsukada and Kimio Hirabayashi
Characterization and Nanofiber Fabrication of Underwater Silk Protein from Stenopsyche marmorata American Chemical Society, National Meething, 2013 Spring 2013 Presenter:Kousaku Ohkawa, Yumi Miura, Takaomi Nomura, Ryoichi Arai, Kimio Hirabayashi, Masuhiro Tsukada, and Koji Abe
Structural and functional analyses of binary pattern designed de novo proteins Enzyme Engineering XXII 2013 Presenter:Arai, R. Kobayashi, N., Fukuda, S., Kurasawa, S. and Hecht, M. H.
Solution structure of IseA, an inhibitor protein of DL-endopeptidases from Bacillus subtilis, reveals a novel fold with a characteristic inhibitory loop International Conference on Structural Genomics 2013 (ICSG2013) 2013 Presenter:Arai, R., Fukui, S., Kobayashi, N. and Sekiguchi, J.
A De Novo Heme Protein, Dnhps1, Created from a 5-Amino Acid Alphabet 27th Annual Symposium of The Protein Society 2013 Presenter:Fukuda, S., Kurasawa, S., and Arai, R.
Crystal structures of MqnD, a menaquinone biosynthetic enzyme, complexed with the product, 1,4-dihydroxy-6-naphthoate, and its analogs 4th International Symposium on Diffraction Structural Biology 2013 (ISDSB2013) 2013 Presenter:Arai, R., Matsuo, K. and Dairi, T.
Isolation of silk proteins from a caddisfly larva, Stenopsyche marmorata Textile Bioengneering Informatics Symposium 2012 2012 Presenter:Kousaku Ohkawa, Yumi Miura, Takaomi Nomura, Ryoichi Arai, Koji Abe, Masuhiro Tsukada and Kimio Hirabayashi
Underwater silk fibers–Biochemical natures for novel textile technology 9th Asia-Pacific Marine Biotechnogy Conference 2012 Presenter:Kousaku Ohkawa, Yumi Miura, Takaomi Nomura, Ryoichi Arai, Koji Abe, Masuhiro Tsukada and Kimio Hirabayashi
Domain-Swapped Dimeric Structure of a Stable and Functional De Novo Four-Helix Bundle Protein WA20, and its Potential Application 18th Symposium of Young Asian Biochemical Engineers' Community (YABEC2012) 2012 Presenter:Arai, R., Kobayashi, N., Kimura, A., Sato, T., and Hecht, M. H.
De novo proteins and interaction analysis using pattern-designed peptide libraries Gordon Research Conference, Intrinsically Disordered Proteins 2012 Presenter:Arai, R., Kobayashi, N., Kimura, A., Teranishi, H., Sato, T., Bradley, L. H., Nishimura, Y., and Hecht, M. H.
Flight density of aquatic insects fauna over river water surface in the middle reaches of the Shinano River, Japan, with emphasis on Trichoptera. 14th International symposium on Trichoptera 2012 Presenter:Hirabayashi K., Ohkawa K., Arai R., Nomura T., Tsukada M. and Abe K.
Function and Three Dimensional Structure of an Autolysin Inhibitor IseA from Bacillus subtilis American Society for Microbiology, General Meeting (asm2012) 2012 Presenter:Junichi Sekiguchi and Ryoichi Arai
Repetitive Sequential Motifs of Underwater Silk Protein from Caddisfly, Stenopsyche marmorata, American Chemical Society, Annual Meeting Spring 2012 2012 Presenter:Kousaku OHKAWA, Yumi MIURA, Takaomi NOMURA, Ryoichi ARAI, Kimio HIRABAYASHI, Masuhiro TSUKADA, and Koji ABE
Domain-swapped dimeric structure of a stable and functional de novo 4-helix bundle protein, WA20 6th International Conference on Advanced Fiber/Textile Materials 2011 2011 Presenter:Kobayashi, N., Kimura, A., Sato, T., Matsuo T., Wang, A. F., Platt, J., Bradley, L. H. Hecht, M. H. and Arai, R.,
Domain-swapped dimeric structure of a de novo 4-helix bundle protein, WA20 PDB40 Symposium (A Special Symposium Celebrating the 40th Anniversary of the Protein Data Bank) 2011 Presenter:Arai, R., Kobayashi, N., Kimura, A., Sato, T., Wang, A. F., Platt, J., Bradley, L. H. and Hecht, M. H.
Crystal structure of a dimeric de novo 4-helix bundle protein WA20 IX European Symposium of The Protein Society 13013, p.87 2011 Presenter:Arai, R., Kimura, A., Kobayashi, N., Sato, T., Wang, A. F., Platt, J., Bradley, L. H. and Hecht, M. H.
Crystal structure of MqnD, a menaquinone biosynthetic enzyme from Thermus thermophilus HB8 Gordon Research Conference, Biopolymers 0 2010 Presenter:Arai, R., Murayama, K., Uchikubo-kamo, T., Nishimoto, M., Toyama, M., Kuramitsu, S., Terada, T., Shirouzu, M. and Yokoyama, S.
Protein Composition in Silk Grand of Caddisfly, Stenopsyche Marmorata, Larva. 14th International Symposium on River and Lake Environments 2009 Presenter:K. Ohkawa, T. Nomura, R.Arai, K. Abe, M. Tsukada, K. Hirabayashi
A four-helix bundle de novo heme protein by phage display screening 7th East Asian Symposium on Polymers for Advanced Technologies (EASPAT 2009) 2009 Presenter:R. Arai, M. H. Hecht
Crystal structure of MqnD (TTHA1568), a menaquinone biosynthetic enzyme from Thermus thermophilus HB8 21st IUBMB and 12th FAOBMB International Congress of Biochemistry and Molecular Biology 2009 Presenter:R. Arai, K. Murayama, T. Uchikubo-Kamo, M. Nishimoto, M. Toyama, S. Kuramitsu, T. Terada, M. Shirouzu, S. Yokoyama
Design and construction of functional artificial proteins: Phage display screening of four-helix bundle de novo proteins 4th International Conference on Advanced Fiber/Textile Materials 2007 in Ueda (ICAFTM2007) 2007 Presenter:R. Arai, M.H. Hecht