論文 A Two-year-old Boy with a Depressed Area in the Groin Lipodystrophia centrifugalis abdominalis infantilis ACTA DERMATO-VENEREOLOGICA,102:adv00643 2022(May) Author:Osawa, Kana; Kiniwa, Yukiko; Okuyama, Ryuhei;
A Case of Apocrine Carcinoma Arising in a Sebaceous Naevus: Detection of HRAS G13R Mutation ACTA DERMATO-VENEREOLOGICA,102:adv00697 2022(May) Author:KATSUIE, Shiho; KINIWA, Yukiko; MIKOSHIBA, Asuka; GOTO, Keisuke; OKUYAMA, Ryuhei;
Toxic Epidermal Necrolysis Caused by Apalutamide: A Case Report of Treatment Using Etanercept with Conventional Steroid Therapy ACTA DERMATO-VENEREOLOGICA,102:adv00723 2022(May) Author:Osawa, Kana; Kiniwa, Yukiko; Shimosato, Yuzuki; Midorikawa, Hirotaka; Shirai, Takushi; Sano, Tasuku; Nakamura, Kenta; Okuyama, Ryuhei;
Prevalence of Psoriatic Arthritis in Nagano Prefecture, Japan, and Efficacy of the Psoriasis Epidemiology Screening Tool: A Real-World Survey TOHOKU JOURNAL OF EXPERIMENTAL MEDICINE,257(3):205-210 2022 Author:Meling, Maureen Tania; Ogawa, Eisaku; Sato, Yuki; Minagawa, Akane; Kiniwa, Yukiko; Okuyama, Ryuhei; Keywords:fingernail alterations; joint symptoms; psoriasis; Psoriasis Epidemiology Screening Tool (PEST); psoriatic arthritis;
Prognoses of patients with melanoma who continue/discontinue anti-programmed death-1 therapy after achieving a complete response in a real-world setting: a multicentre retrospective study BRITISH JOURNAL OF DERMATOLOGY 2022 Author:Kato, Junji; Namikawa, Kenjiro; Uehara, Jiro; Nomura, Motoo; Nakamura, Yasuhiro; Uhara, Hisashi; Uchi, Hiroshi; Yoshikawa, Shusuke; Kiniwa, Yukiko; Nakamura, Yoshiyuki; Miyagawa, Takuya; Matsushita, Shigeto; Takenouchi, Tatsuya; Hatta, Naohito; Ohno, Fumitaka; Maeda, Taku; Fukushima, Satoshi; Yamazaki, Naoya;
Case of bullous pemphigoid following coronavirus disease 2019 vaccination JOURNAL OF DERMATOLOGY,48(12):E606-E607 2021(Dec.) Author:Nakamura, Kenta; Kosano, Megumi; Sakai, Yuzuki; Saito, Nana; Takazawa, Yuko; Omodaka, Toshikazu; Kiniwa, Yukiko; Okuyama, Ryuhei;
Increased expression of secreted protein acidic and rich in cysteine and tissue inhibitor of metalloproteinase-3 in epidermotropic melanoma metastasis JOURNAL OF DERMATOLOGY,48(11):1772-1779 2021(Nov.) Author:Meling, Maureen Tania; Kiniwa, Yukiko; Ogawa, Eisaku; Sato, Yuki; Okuyama, Ryuhei; Keywords:beta-catenin; epidermotropic melanoma metastasis; neural cadherin; secreted protein acidic and rich in cysteine; tissue inhibitor of metalloproteinase-3;
TIGIT/CD155 axis mediates resistance to immunotherapy in patients with melanoma with the inflamed tumor microenvironment JOURNAL FOR IMMUNOTHERAPY OF CANCER,9(11):e003134 2021(Nov.) Author:Kawashima, Shusuke; Inozume, Takashi; Kawazu, Masahito; Ueno, Toshihide; Nagasaki, Joji; Tanji, Etsuko; Honobe, Akiko; Ohnuma, Takehiro; Kawamura, Tatsuyoshi; Umeda, Yoshiyasu; Nakamura, Yasuhiro; Kawasaki, Tomonori; Kiniwa, Yukiko; Yamasaki, Osamu; Fukushima, Satoshi; Ikehara, Yuzuru; Mano, Hiroyuki; Suzuki, Yutaka; Nishikawa, Hiroyoshi; Matsue, Hiroyuki; Togashi, Yosuke; Keywords:costimulatory and inhibitory t-cell receptors; drug therapy; combination; immunotherapy; melanoma; tumor microenvironment;
Real-world efficacy of anti-PD-1 antibody or combined anti-PD-1 plus anti-CTLA-4 antibodies, with or without radiotherapy, in advanced mucosal melanoma patients: A retrospective, multicenter study EUROPEAN JOURNAL OF CANCER,157:361-372 2021(Nov.) Author:Umeda, Yoshiyasu; Yoshikawa, Shusuke; Kiniwa, Yukiko; Maekawa, Takeo; Yamasaki, Osamu; Isei, Taiki; Matsushita, Shigeto; Nomura, Motoo; Nakai, Yasuo; Fukushima, Satoshi; Saito, Shintaro; Takenouchi, Tatsuya; Tanaka, Ryo; Kato, Hiroshi; Otsuka, Atsushi; Matsuya, Taisuke; Baba, Natsuki; Nagase, Kotaro; Inozume, Takashi; Onuma, Takehiro; Kuwatsuka, Yutaka; Fujimoto, Noriki; Kaneko, Takahide; Onishi, Masazumi; Namikawa, Kenjiro; Yamazaki, Naoya; Nakamura, Yasuhiro; Keywords:Mucosal melanoma; Radiotherapy; Abscopal effect; Anti-PD-1 antibody; Anti-CTLA-4 antibody; Nivolumab; Pembrolizumab; Ipilimumab;
Case of annular pustular psoriasis/circinate erythematous psoriasis induced by hydroxychloroquine in a patient with systemic lupus erythematosus: Possible association with CARD-14 mutation J Dermatol 2021(Jun. 02) Author:Hirotaka Midorikawa, Yukiko Kiniwa, Akane Minagawa, Kana Osawa, Takushi Shirai, Tasuku Sano, Kenta Nakamura, Atsuko Ashida, Ken-Ichi Ueno, Takuya Takeichi, Masashi Akiyama, Ryuhei Okuyama
CCL5 production by fibroblasts through a local renin–angiotensin system in malignant melanoma affects tumor immune responses. J Cancer Res Clin Oncol 2021(Mar. 26) Author:Nakamura K, Kiniwa Y, Okuyama R.
Usefulness of monitoring circulating tumor cells as a therapeutic biomarker in melanoma with BRAF mutation BMC Cancer,21(1):287 2021(Mar. 17) Author:Kiniwa Y, Nakamura K, Mikoshiba A, Ashida A, Akiyama Y, Morimoto A, Okuyama R
Recent advances in molecular targeted therapy for unresectable and metastatic BRAF-mutated melanoma. Jpn J Clin Oncol,51(3):315-20 2021(Mar.) Author:Kiniwa Y, Okuyama R
Ligand bound fatty acid binding protein 7 (FABP7) drives melanoma cell proliferation via modulation of Wnt/β-catenin signaling. Pharm Res,38(3):479-490 2021(Mar.) Author:Umaru BA, Kagawa Y, Shil SK, Arakawa N, Pan Y, Miyazaki H, Kobayashi S, Yang S, Cheng A, Wang Y, Shinoda Y, Kiniwa Y, Okuyama R, Fukunaga K, Owada Y
Comparing the clinical efficacies of anti-PD-1 antibody monotherapy and anti-PD-1 and anti-CTLA-4 combination therapy as first-line immunotherapy in Japanese advanced acral melanoma: A retrospective, multicenter study (JAMP-neo study). JOURNAL OF CLINICAL ONCOLOGY,39(15) 2021 Author:Nakamura, Yasuhiro; Kiniwa, Yukiko; Kato, Hiroshi; Yamasaki, Osamu; Maekawa, Takeo; Matsushita, Shigeto; Takenouchi, Tatsuya; Inozume, Takashi; Nakai, Yasuo; Fukushima, Satoshi; Saito, Shintaro; Otsuka, Atsushi; Fujimoto, Noriki; Isei, Taiki; Baba, Natsuki; Matsuya, Taisuke; Tanaka, Ryo; Kaneko, Takahide; Onishi, Masazumi; Yoshikawa, Shusuke;
Case of bullous pemphigoid following coronavirus disease 2019 vaccination JOURNAL OF DERMATOLOGY 2021 Author:Nakamura, Kenta; Kosano, Megumi; Sakai, Yuzuki; Saito, Nana; Takazawa, Yuko; Omodaka, Toshikazu; Kiniwa, Yukiko; Okuyama, Ryuhei;
Chemokine level predicts the therapeutic effect of anti-PD-1 antibody (nivolumab) therapy for malignant melanoma ARCHIVES OF DERMATOLOGICAL RESEARCH 2021 Author:Nakamura, Kenta; Ashida, Atsuko; Kiniwa, Yukiko; Okuyama, Ryuhei; Keywords:C-C motif chemokine 5; Chemokine; C-X-C motif chemokine ligand 12; Melanoma; PD-1;
Successful treatment of cutaneous infection due toPurpureocillium lilacinumusing voriconazole JOURNAL OF DERMATOLOGY,47(9):E342-E343 2020(Sep.) Author:Suzuki, Rika; Kiniwa, Yukiko; Shirai, Takushi; Takazawa, Yuko; Natori, Tatsuya; Mochizuki, Takashi; Okuyama, Ryuhei;
Detecting copy number alterations of oncogenes in cell-free DNA to monitor treatment response in acral and mucosal melanoma JOURNAL OF DERMATOLOGICAL SCIENCE,97(3):172-178 2020(Mar.) Author:Mikoshiba, Asuka; Ashida, Atsuko; Sakaizawa, Kaori; Kiniwa, Yukiko; Okuyama, Ryuhei;
p63 overexpression in the epidermis of spiny keratoderma JOURNAL OF DERMATOLOGY,47(1):E29-E30 2020(Jan.) Author:Widyasaputra, Maureen Tania; Ogawa, Eisaku; Saiki, Minoru; Kiniwa, Yukiko; Okuyama, Ryuhei;
Anti-PD1 checkpoint inhibitor therapy in acral melanoma: a multicenter study of 193 Japanese patients. Ann Oncol,31(9):1198-1206 2020 Author:Nakamura Y, Namikawa K, Yoshino K, Yoshikawa S, Uchi H, Goto K, Nakamura Y, Fukushima S, Kiniwa Y, Takenouchi T, Uhara H, Kawai T, Hatta N, Funakoshi T, Teramoto Y, Otsuka A, Doi H, Ogata D, Matsushita S, Isei T, Hayashi T, Shibayama Y, Yamazaki N.
Circulating Tumour DNA Reflects Tumour Burden Independently of Adverse Events Caused by Systemic Therapies for Melanoma ACTA DERMATO-VENEREOLOGICA,99(12):1184-1185 2019(Nov.) Author:Ashida, Atsuko; Sakaizawa, Kaori; Mikoshiba, Asuka; Kiniwa, Yukiko; Okuyama, Ryuhei;
Improvement of porphyria cutanea tarda following treatment of hepatitis C virus by direct-acting antivirals: A case report JOURNAL OF DERMATOLOGY,46(5):E149-E151 2019(May) Author:Nihei, Tatsuya; Kiniwa, Yukiko; Mikoshiba, Yasutomo; Joshita, Satoru; Okuyama, Ryuhei;
Identification of genetic alterations in extramammary Paget disease using whole exome analysis JOURNAL OF DERMATOLOGICAL SCIENCE,94(1):229-235 2019(Apr.) Author:Kiniwa, Yukiko; Yasuda, Jun; Saito, Sakae; Saito, Rumiko; Motoike, Ikuko N.; Danjoh, Inaho; Kinoshita, Kengo; Fuse, Nobuo; Yamamoto, Masayuki; Okuyama, Ryuhei;
Presence of antibodies to striated muscle and acetylcholine receptor in association with occurrence of myasthenia gravis with myositis and myocarditis in a patient with melanoma treated with an anti-programmed death 1 antibody EUROPEAN JOURNAL OF CANCER,106:193-195 2019(Jan.) Author:Shirai, T.; Kiniwa, Y.; Sato, R.; Sano, T.; Nakamura, K.; Mikoshiba, Y.; Ohashi, N.; Sekijima, Y.; Okuyama, R.;
Sarcoidosis mimicking malar rash: a case of lupus pernio EUROPEAN JOURNAL OF DERMATOLOGY,29(3):331-332 2019 Author:Sato, Rika; Kiniwa, Yukiko; Shirai, Takushi; Okuyama, Ryuhei;
Type 1 diabetes in a melanoma patient treated with ipilimumab after nivolumab JOURNAL OF DERMATOLOGY,45(10):E289-E290 2018(Oct.) Author:Omodaka, Toshikazu; Kiniwa, Yukiko; Sato, Yuki; Suwa, Manabu; Sato, Misato; Yamaguchi, Tomohiko; Sato, Ai; Miyake, Tomomi; Okuyama, Ryuhei;
Diversity of circulating tumor cells in peripheral blood: Detection of heterogeneous BRAF mutations in a patient with advanced melanoma by single-cell analysis JOURNAL OF DERMATOLOGICAL SCIENCE,90(2):211-213 2018(May) Author:Kiniwa, Yukiko; Nakamura, Kenta; Mikoshiba, Asuka; Akiyama, Yasuyuki; Morimoto, Atsushi; Okuyama, Ryuhei;
Involvement of local renin-angiotensin system in immunosuppression of tumor microenvironment CANCER SCIENCE,109(1):54-64 2018(Jan.) Author:Nakamura, Kenta; Yaguchi, Tomonori; Ohmura, Gaku; Kobayashi, Asuka; Kawamura, Naoshi; Iwata, Takashi; Kiniwa, Yukiko; Okuyama, Ryuhei; Kawakami, Yutaka;
Expression of Mucin 1 in Mycosis Fungoides Tumour Cells: A Case Report ACTA DERMATO-VENEREOLOGICA,97(6):747-748 2017(Jun.) Author:Shirai, Takushi; Kiniwa, Yukiko; Asaka, Shiho; Shimojo, Yasuyo; Kamijo, Fuminao; Okuyama, Ryuhei;
Hypohidrotic ectodermal dysplasia: A report of two cases JOURNAL OF DERMATOLOGY,44(4):479-481 2017(Apr.) Author:Miyake, Tomomi; Kiniwa, Yukiko; Kosho, Tomoki; Nakano, Hajime; Okuyama, Ryuhei;
Polyarteritis nodosa in a patient with haemophilia A EUROPEAN JOURNAL OF DERMATOLOGY,27(2):203-204 2017(Mar.) Author:Tsuji, Asuka; Kiniwa, Yukiko; Kamijo, Fuminao; Miyake, Tomomi; Ohashi, Atsuko; Senoo, Noriko; Urushihata, Kazuhisa; Okuyama, Ryuhei;
Intratumoral expression levels of PD-L1, GZMA, and HLA-A along with oligoclonal T cell expansion associate with response to nivolumab in metastatic melanoma ONCOIMMUNOLOGY,5(9) 2016 Author:Inoue, Hiroyuki; Park, Jae-Hyun; Kiyotani, Kazuma; Zewde, Makda; Miyashita, Azusa; Jinnin, Masatoshi; Kiniwa, Yukiko; Okuyama, Ryuhei; Tanaka, Ryota; Fujisawa, Yasuhiro; Kato, Hiroshi; Morita, Akimichi; Asai, Jun; Katoh, Norito; Yokota, Kenji; Akiyama, Masashi; Ihn, Hironobu; Fukushima, Satoshi; Nakamura, Yusuke;
A case of Kindler syndrome with severe esophageal stenosis INTERNATIONAL JOURNAL OF DERMATOLOGY,54(4):E106-E108 2015(Apr.) Author:Ohashi, Atsuko; Kiniwa, Yukiko; Okuyama, Ryuhei; Kosho, Tomoki; Suga, Tomoaki; Has, Cristina; Kubo, Hitomi;
A nonsense nucleotide substitution in the oculocutaneous albinism II gene underlies the original pink-eyed dilution allele (Oca2p) in mice. Exp Anim. Exp Anim.,Epub ahead of print:Epub ahead of print 2015(Jan. 22) Author:Shoji H, Kiniwa Y, Okuyama R, Yang M, Higuchi K, Mori M.
Identification of DRG-1 As a Melanoma-Associated Antigen Recognized by CD4(+) Th1 Cells PLOS ONE,10(5) 2015 Author:Kiniwa, Yukiko; Li, Jiang; Wang, Mingjun; Sun, Chuang; Lee, Jeffrey E.; Wang, Rong-Fu; Wang, Helen Y.;
5-Hydroxymethylcytosine as a useful marker to differentiate between malignant melanomas and benign melanocytic nevi. J Dermatol Sci.,73(2):161-3 2014(Feb. 01) Author:Uchiyama R,Uhara H, Uchiyama A, Ogawa E, Takazawa Y, Ashida A, Koga H, Hayashi K, Kiniwa Y, Okuyama R
IgA/IgG Pemphigus with Infiltration of Neutrophils and Eosinophils in an Ulcerative Colitis Patient. Acta Derm Venereol,94:in press 2014 Author:Uchiyama R, Ishii N, Arakura F, Kiniwa Y, Nakazawa K, Uhara H, Hashimoto T, Okuyama R.
Generalized pustulosis associated with disseminated Mycobacterium avium infection in a non-AIDS patient. Eur J Dermatol.,24(3):402-3 2014 Author:Asai Y, Kiniwa Y, Okada N, Futatsugi T, Ushiki A, Uhara H, Okuyama R.
Toll-like receptor 4 signaling promotes the migration of human melanoma cells. Tohoku J Exp Med,234:57-65 2014 Author:Takazawa Y, Kiniwa Y, Ogawa E, Uchiyama A, Ashida A, Uhara H, Goto Y, Okuyama R.
NRAS mutations in primary and metastatic melanomas of Japanese patients. Int J Clin Oncol,.:. 2013(Jun. 06) Author:Uhara H, Ashida A, Koga H, Ogawa E, Uchiyama A, Uchiyama R, Hayashi K, Kiniwa Y, Okuyama R.,
Low p53 positivity in verrucous skin lesion in diabetic neuropathy occurring on the dorsum of the foot. Int J Dermatol,52(3):378-80 2013(Mar.) Author:Ashida A, Kiniwa Y, Kobayashi A, Okuyama R
Mutation analysis of BRAF and KIT in circulating melanoma cells at the single cell level British J Cancer,106:939-46 2012(Feb. 01) Author:Sakaizawa K, Goto Y, Kiniwa Y, Uchiyama A, Harada K, Shimada S, Saida T, Ferrone S, Takata M, Uhara H, Okuyama R.
A case of epidermolysis bullosa acquisitaassociated with laryngeal stenosis. Acta Derm Venereol,92:93-94 2012(Jan. 15) Author:Kiniwa Y, Ashida A, Ohashi A, Kitoh R, Fukuda S, Hashimoto T, Okuyama R.
A case of angiosarcoma arising on a closed shunt in a patient with chronic renal failure. J Am Acad Dermatol,65(4):882-883 2011(Apr.) Author:Kamijo F, Kiniwa Y, Goto Y, Tanaka A, Kobayashi A, Shirota S, Fukuzawa M, Saida S
Thermal Angioedema Induced by Hot Water Acta Derm Veneneol,91(3):343-344 2011(Mar.) Author:Kobayashi A, Uhara H, Ashida A, Kiniwa Y, Okuyama R
A case of systemic anaplastic large cell lymphoma with “Hodgkin-like” appearance and skin involvement mimicking lymphomatoid papulosis. J Cutan Pathol,,8(1):38-42 2011 Author:Kiniwa Y, Ide Y, Fukushima M,Asano N, Saida T
NADPH oxidase 4 contributes to transformation phenotype of melanoma cells by regulating G2-M cell cycle progression Cancer Res,69(6):2647-54 2009 Author:YamauraM, MitsushitaJ, Furuta, S, Kiniwa Y,Ashida A, Goto Y, Shang W. H, Kubodera M, Kato M, Takata M, Saida T,Kamata T,
Tumor-infiltrating gammadelta T cells suppress T and dendritic cell function via mechanisms controlled by a unique toll-like receptor signaling pathway. Immunity,27(2):334-348 2007 Author:Peng G, Wang HY, Peng W, Kiniwa Y , Seo KH , Wang RF
CD8+ Foxp3+ regulatory T cells mediate immune suppression in prostate cancer Clin Cancer Res,13(23):6947-58 2007 Author:Kiniwa Y, Wang HY, Peng W, Peng G, Wheeler T, Thompson T, Wang RF
Toll-like receptor 8-mediated reversal of CD4+ regulatory T cell function. Science.,309:1380-1384 2005 Author:Peng G, Guo Z, Kiniwa Y, Voo KS, Peng W, Fu T, Wang DY, Li Y, Wang HY, Wang RF
Identification of bladder cancer antigens recognized by IgG antibodies of a patient with metastatic bladder cancer Int J Cancer,108(5):712-724 2004 Author:Ito K, Fujita T, Akada M, Kiniwa Y, Tsukamoto M, Yamamoto A, Matsuzaki Y, Matsushita M, Asano T, Nakashima J, Tachibana M, Hayakawa M, Ikeda H, Murai M, Kawakami Y
Tumor-specific human CD4+ regulatory T cells and their ligands: implications for immunotherapy Immunity,20(1):107-118 2004 Author:Wang HY, Lee DA, Peng G, Guo Z, Li Y, Kiniwa Y, Shevach EM, Wang RF
Tumor antigens isolated from a patient with vitiligo and T-cell-infiltrated melanoma CANCER RESEARCH,61(21):7900-7907 2001 Author:Kiniwa, Y; Fujita, T; Akada, M; Ito, K; Shofuda, T; Suzuki, Y; Yamamoto, A; Saida, T; Kawakami, Y
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