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能勢博  ノセ ヒロシ

教員組織学術研究院(医学系)電話番号
教育組織先鋭領域融合研究群 バイオメディカル研究所 先端疾患予防学部門FAX番号
職名教授メールアドレス
住所ホームページURL

更新日:2016/01/12

プロフィール

研究分野
運動生理学
環境生理学
温熱生理学
現在の研究課題
暑熱環境下運動時の血液量調節機構とその生理的意義

脱水回復時の水分塩分摂取機構

運動トレーニング、環境適応過程における体液循環調節機構

高齢者の体液調節が好気的運動能と体温調節能に与える影響

所属学会
所属学会
日本生理学会
日本体力医学会
日本生気象学会
米国生理学会
米国スポーツ医学協会
学歴
出身学校・専攻等(大学院を除く)
1979 , 京都府立医科大学 , 医学部

取得学位
医学博士
受賞学術賞
1992 , 青蓮賞(京都府立医科大学学友会研究奨励賞)
研究職歴等
研究職歴
2003- , 大学院医学系研究科・加齢適応医科学系専攻・スポーツ医科学分野 教授
1995-2003 , 医学部付属加齢適応研究センター・スポーツ医学分野 教授
1993-1995 , 京都府立医科大学第一生理学教室勤務 教授
1988-1993 , 京都府立医科大学第一生理学教室勤務 講師
1979-1988 , 京都府立医科大学第一生理学教室勤務 助手

研究職歴以外の職歴
2004- , NPO法人熟年体育大学リサーチセンター・理事長

留学歴
1985-1988 , 米国Yale大学医学部John B. Pierce研究所博士研究員

研究活動業績

研究業績(著書・
発表論文等)
著書
Physiological Bases of Human Performance during Work and Exercise
Churchil&Livingstone , Physiological Bases of Human Performance during Work and Exercise , :487-490 2008
Author:H Nose and S Montain


Nutrition, Exercise, and Environmental Stress(Volume 4)
"Cooper Publishings, Travere City, MI" 2004
Author:Nose H, Joyner M, Miki K(eds)


Exercise, Nutrition, and Environmental Stress (vol.1) 総頁275
Cooper Publishings, Carmel, IN 2000
Author:H. Nose, C.V. Gisolfi, and K. Imaizumi


The 1997 Nagano Symposium on Sports Sciences, 総頁646
Cooper Publishings, Carmel, IN 1998
Author:H. Nose, E.R.Nadel, and T. Morimoto 編著


Fluid Replacement and Heat Stress, 総頁242中34頁
National Academy Press, Washington D.C , :127-160 1994
Author:H. Nose, G.W. Mack, X.Shi, and E.R.Nadel


論文
Interval Walking Training for Middle-Aged and Older People: Methods and Evidence
IEICE TRANSACTIONS ON COMMUNICATIONS,E97B(3):534-539 2014
Author:Nose, H


Exercise Effects on Methylation of ASC Gene
INTERNATIONAL JOURNAL OF SPORTS MEDICINE,31(9):671-675 2010
Author:Nakajima, K.; Takeoka, M.; Mori, M.; Hashimoto, S.; Sakurai, A.; Nose, H.; Higuchi, K.; Itano, N.; Shiohara, M.; Oh, T.; Taniguchi, S.


Vasopressin V1a receptor polymorphism and high-intensity interval walking training effects in middle-aged and older people.
Hypertension,55(3):747-754 2010
Author:Masuki S, Mori M, Tabara Y, Miki T, Morikawa M, Miyagawa K, Higuchi K, and Nose H for the Shinshu University Genetic Research Consortium.


Effects of a 3 month high-intensity interval walking training on physical fitness and cardiovascularrisk factors in middle-aged individuals.
J. Prim. Care&Comm. Health.,1:104-110 2010
Author:14. Lalande S, Okazaki K, Yamazaki T, Nose H, Warren BA, Olsen KD, Joyner MJ, and Johnson BD


Protein and carbohydrate supplementation during 5-day aerobic training enhanced plasma volume expansion and thermoregulatory adaptation in young men
J Appl Physiol.,109:1247-1255 2010
Author:Goto M, Okazaki K, Kamijo Y, Ikegawa S, Masuki S, Miyagawa K, and Nose H


Sportology and high intensity interval walking training in aging society.
Juntendo Med. J,56:251-256 2010
Author:Nose H, Morikawa M, Masuki S, Yamazaki T, Nemoto K, Okazaki K, Kmaijo Y, and Genno H


Reduced hyperthermia-induced cutaneous vasodilation and enhanced exercise-induced plasma water loss at simulated high altitude (3,200m) in humans.
J. Appl. Physiol. 2010
Author:Miyagawa K, Kamijo Y, Ikegawa S, Goto M, and Nose H


Effects of mild calorie restriction and high-intensity interval walking in middle-aged and older overweight Japanese.
Exp Gerontol,44(10):666-675 2009
Author:Sawashita J, Onitsuka S, Gen-no H, Ishikawa S, Iino F, Tateishi N, Murakami T, Seki Y, Nagaiwa T, Hanaoka M, Hama S, Nose H, and Higuchi K


Genetic basis of inter-individual variability in the effects of exercise on the alleviation of lifestyle-related diseases.
J Physiol (Lond),587:5577-5584 2009
Author:Mori M, Higuchi K, Sakurai A, Tabara Y, Miki T, and Nose H.


A new device to estimate VO2 during incline walking by accelerometry and barometry.
Med Sci Sports Exerc,,41(12):2213-2219 2009
Author:Yamazaki T, Gen-no H, Kamijo Y, Okazaki K, Masuki S, and Nose H.


Pressor responses to isometric biting are evoked by somatosensory receptors in periodontal tissue in humans.
J Appl Physiol,107:531-539 2009
Author:Okada Y, Kamijo Y, Okazaki K, Masuki S, Goto M, and Nose H


Impact of protein and carbohydrate supplementation on plasma volume expansion and thermoregulatory adaptation by aerobic training in older men.
J Appl Physio,107(3):725-733 2009
Author:Okazaki K, Ichinose T, Mitono H, Chen M, Masuki S, Endoh H, Hayase H, Tatsuya Doi T, and Nose H.


Protein and carbohydrate supplementation after exercise increases plasma volume and albumin content in older and young men.
J Appl Physiol,107(3):770-775 2009
Author:Okazaki K, Hayase H, Ichinose T, Mitono H, Doi T, and Nose H.


Protein and carbohydrate supplementation increases aerobic and thermo-regulatory capacities.
J Physiol (Lond),587:5585-5590 2009
Author:Okazaki K, Goto M, and Nose H.


Beyond epidemiology: field studies and the physiology laboratory as the whole world.
J Physiol (Lond),587(23):5569-5575 2009
Author:Nose H, Morikawa M, Yamazaki T, Nemoto K, Okazaki K, Masuki S, Kamijo Y, and Gen-no H


Physical fitness and indices of lifestyle-related diseases before and after interval walking training in middle-aged and older males and females
British J. Sports Med. 2009
Author:2. Morikawa M, Okazaki K, Masuki S, Kamijo Y, Yamazaki T, Gen-noH, and NoseH


Increased cerebral activity suppresses baroreflex control of heart rate in freely moving mice.
J Physiol (Lond),,587(23):5783-5794 2009
Author:Masuki S and NoseH


Chronic high-intensity interval walking exercise alters DNA methylation in normal middle-aged and older subjects
JOURNAL OF AGING AND PHYSICAL ACTIVITY,16:S106-S106 2008
Author:Nakajima, K; Takeoka, M; Masayuki, M; Akihiro, S; Nose, H; Higuchi, K; Itano, N; Taniguchi, S


Effects of high-intensity interval walking training on physical fitness and blood pressure in middle-agedand older people
Mayo Clinic Medicine,82(7):803-811 2007
Author:KEN-ICHI NEMOTO, HIROKAZU GEN-NO, SHIZUE MASUKI, KAZUNOBU OKAZAKI, HIROSHI NOSE


Walking regimen to increase aerobic capacity and thigh muscle strength for elderly people by accelerometry
FASEB JOURNAL,20(4):A383-A383 2006
Author:Nemoto, K; Genno, H; Nose, H


Heat illness during working and preventive considerations from body fluid homeostasis
INDUSTRIAL HEALTH,44(3):345-358 2006
Author:Kamijo, YI; Nose, H


Enhanced sensitivity of cutaneous vasodilation and cardiac stroke volume after 10-day exercise training in humans
FASEB JOURNAL,19(5):A1193-A1194 2005
Author:Ichinose, T; Okazaki, K; Masuki, S; Mitono, H; Chen, M; Endoh, H; Nose, H


Effects of hyperosmolality on maintenance of arterial pressure in dehydrated and exercising men in a hot environment. Exercise, Nutrition and Environmental Stress, vol 4, Eds. Nose H, Joyner MJ, and Miki K
Cooper Publishing, Traverse City.,:245-256 2005
Author:Kamijo Y, Nose H


Exercise, Nutrition, and Environmental Stress(Vol 4)
Cooper Publishing, Traverse City, MI. 2005
Author:Nose H, Joyner MJ, Miki K


Variation of a-adrenergic vasoconstrictor response changes baroreflex sensitivity. Exercise, Nutrition, and Environmenta Sltress, vol 4 Eds
Nose H, Joyner MJ, Miki K, Cooper Publishing, Traverse City.,:155-128 2005
Author:Masuki S, Joyner MJ, Nose H


Transient cutaneous vasodilatation and hypotension after drinking in dehydrated and exercising men
J Physiol Lond,568(2):689-698 2005
Author:Kamijo Y, Okumoto T, Takeno Y, Okazaki K, Inaki M, Masuki S, Nose H


Reduced alpha-adrenoceptor responsiveness and enhanced baroreflex sensitivity in Cry-deficient mice lacking a biological clock
J Physiol (Lond),566(1):213-224 2005
Author:Masuki S, Todo T, Nakano Y, Okamura H, Nose H


Acute hypoosmolality attenuates the suppression ofcutaneous vasodilation with increased exercise intensity
J Appl Physiol,99(3):902-908 2005
Author:Mitono H, Endoh H, Okazaki K, Ichinose T, Masuki S, Takamata A, Nose H


Ten-day endurance training attenuates the hyperosmotic suppression of cutaneous vasodilation during exercise but not sweating
J Appl Physiol,99(1):237-243 2005
Author:Ichinose T, Okazaki K, Masuki S, Mitono H, Chen M, Endoh H, Nose H


Hyperosmotic inhibition of cutaneous vasodilation was suppressed by hypervolemia after endurance training in a warm environment
FASEB JOURNAL,18(5):A1099-A1099 2004
Author:Ichinose, T; Okazaki, K; Masuki, S; Mitono, H; Chen, M; Endoh, H; Nose, H


Protein&CHO supplementation during aerobic training increased plasma volume and thermoregulatory capacity in older men
FASEB JOURNAL,18(5):A1099-A1099 2004
Author:Okazaki, K; Ichinose, T; Mitono, H; Masuki, S; Endoh, H; Chen, M; Hayase, H; Doi, T; Nose, H


Circadian rhythm of arterial pressure regulation in CRY double knockout mice
FASEB JOURNAL,18(4):A650-A650 2004
Author:Masuki, S; Todo, T; Nakano, Y; Okamura, H; Nose, H


Regional differences in the expression of Fos-like immunoreactivity after central salt loading in conscious rats: modulation by endogenous vasopressin and role of the area postrema
Brain Research,1022(1-2):182-194 2004
Author:Kato K, Chu C-P, Kannan H, Ishida Y, Nishimori T, Nose H


Enhanced baroreflex sensitivity in free-moving calponin knockout mice
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY,284(3):H939-H946 2003
Author:Masuki, S;Takeoka, M; Taniguchi, S; Nose, H


Protein&CHO intake after a bout of intense exercise increased plasma volume and protein content in younger and older men
FASEB JOURNAL,17(5):A943-A943 2003
Author:Okazaki, K; Hayase, H; Ichinose, T; Mitono, H; Doi, T; Nose, H


Impaired arterial pressure regulation during exercise due to enhanced muscular vasodilation in calponin knockout mice
FASEB JOURNAL,17(4):A431-A431 2003
Author:Masuki, S; Takeoka, M; Taniguchi, S; Nose, H


Forearm skin blood flow response to exercise at simulated high altitude of 4,000m
FASEB JOURNAL,17(4):A32-A32 2003
Author:Endoh, H; Kamijo, Y; Takeno, Y; Okazaki, K; Masuki, S; Mitono, H; Nose, H


Exercise intensity dependent hyperosmolality caused the upward shift of esophageal temperature threshold for forearm skin vasodilation
FASEB JOURNAL,17(4):A31-A31 2003
Author:Mitono, H; Endoh, H; Okazaki, K; Itinose, T; Masuki, S; Nose, H


Safer mountain climbing using the climbing heartbeat index
INTERNATIONAL JOURNAL OF BIOMETEOROLOGY,48(1):15-19 2003
Author:Sakai, A; Nose, H


Triaxial accelerometry to evaluate walkingefficiency in older subjects
MEDICINE AND SCIENCE IN SPORTS AND EXERCISE,35(10):1766-1772 2003
Author:Iwashita, S; Takeno, Y; Okazaki, K; Itoh, JI; Kamijo, YI; Masuki, S; Yanagidaira, Y; Nose, H


Impaired arterial pressure regulation during exercise due to enhanced muscular vasodilatation in calponin knockout mice
JOURNAL OF PHYSIOLOGY-LONDON,553(1):203-212 2003
Author:Masuki, S; Takeoka, M; Taniguchi, S; Yokoyama, M; Nose, H


Arterial baroreflex control of muscle blood flow at the onset of voluntary locomotion in mice
JOURNAL OF PHYSIOLOGY-LONDON,553(1):191-201 2003
Author:Masuki, S; Nose, H


Diurnal rhythm disorder of behavioral activity in SAMP1 mice is partially normalized by spontaneous wheel running
PHYSIOLOGY&BEHAVIOR,80(2-3):195-201 2003
Author:Yanagidaira, Y; Higuchi, K; Nose,H


Effects of exercise training on thermoregulatory responses and blood volume in older men
JOURNAL OF APPLIED PHYSIOLOGY,93(5):1630-1637 2002
Author:Okazaki, K; Kamijo, YI; Takeno, Y; Okumoto, T; Masuki, S; Nose, H


Thermoregulatory and aerobic changes after endurance training in a hypobaric hypoxic and warm environment
J. Appl. Physiol,91(4):1520-1528 2001
Author:Y. Takeno, Y. Kamijo, H. Nose


Thermoregulatory and aerobic change after 10-day endurance training in a hypobaric hypoxic and warm environment.
FASEB JOURNAL,14(4):A615-A615 2000
Author:Takeno, Y; Kamijo, Y; Nose, H


Plasma lactate concentration and muscle blood now during dynamic exercise with continuous negative-pressure breathing
FASEB JOURNAL,14(4):A325-A325 2000
Author:Kamijo, Y; Takeno, Y; Sakai, A; Inaki, M; Okumoto, T; Itoh, J; Masuki, S; Yanagidaira, Y; Nose, H


Effect of acute hypoxia on vasopressin release and intravascular fluid during dynamic exercise in humans
AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY,279(1):R161-R168 2000
Author:Takamata, A; Nose, H; Kinoshita, T; Hirose, M; Itoh, T; Morimoto, T


Plasma lactate concentration and muscle blood flow during dynamic exercise with negative-pressure breathing
J. Appl. Physiol,89(6):2196-2205 2000
Author:Y. Kamijo, Y. Takeno, H. Nose


Comparison between tail skin blood flow measurements by ultrasonic Doppler flowmetry and plethysmography during heating in anesthetized rats
JAPANESE JOURNAL OF PHYSIOLOGY,49(1):121-124 1999
Author:Nakajima, Y; Nose, H; Takamata, A


Effect of continuous negative-pressure breathing on skin blood flow during exercise in a hot environment
JOURNAL OF APPLIED PHYSIOLOGY,84(6):1845-1851 1998
Author:Nagashima, K; Nose, H; Takamata, A; Morimoto, T


Plasma hyperosmolality and arterial pressure regulation during heating in dehydrated and awake rats
Am.J. Physiol.,275(5):R1703-R1711 1998
Author:Y. Nakajima, H. Nose, A. Takamata


Integrative regulations of body temperature and bodyfluid in humans exercising in a hot environment
Int. J. Biometeorol,40(1):42-49 1997
Author:H. Nose, and A.Takamata


Cerebrospinal fluid sodium concentration and osmosensitive sites related to arterial pressure in anaesthetized rats
PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY,431(6):807-813 1996
Author:Hirose, M; Nose, H; Chen, M; Yawata, T


その他
Inter-individual variability in the improvement of physiological risk factors for disease: gene polymorphism or simply regressionto the mean ?
J. Physiol.(Lond.) , 588:1023-1025 2010
Author:Mori M, Higuchi K, and Nose H

研究業績(芸術系の活動、フィールドワーク等)
フィールドワーク
高地医学に関するフィールドワーク「中国天山山脈・未踏峰ボゴダオーラ(5,445m) 登頂」

その他
「松本市熟年体育大学」の学術的サポート
信州大学医学部山岳部常念岳夏季診療所長

教育活動実績

授業等
2002 , 生理学