論文 Activation of the inflammasome drives peritoneal deterioration in a mouse model of peritoneal fibrosis. FASEB J.,37(9):e23129 2023(Sep.) Author:Kadoya H, Hirano A, Umeno R, Kajimoto E, Iwakura T, Kondo M, Wada Y, Kidokoro K, Kishi S, Nagasu H, Sasaki T, Taniguchi S, Takahashi M, Kashihara N.
Endothelial Dysfunction Accelerates Impairment of Mitochondrial Function in Ageing Kidneys via Inflammasome Activation. Int J Mol Sci.,22(17):9269 2021(Aug.) Author:Wada Y, Umeno R, Nagasu H, Kondo M, Tokuyama A, Kadoya H, Kidokoro K, Taniguchi S, Takahashi M, Sasaki T, Kashihara N.
Potentiated antitumor effects of APS001F/5-FC combined with anti-PD-1 antibody in a CT26 syngeneic mouse model. Biosci Biotechnol Biochem.,85(2):324-331 2021(Feb.) Author:Shioya K, Matsumura T, Seki Y, Shimizu H, Nakamura T, Taniguchi S.
In Situ Delivery and Production System (iDPS) of Anti-Cancer Molecules with Gene-Engineered Bifidobacterium J Pers Med,11(6) 2021 Author:Taniguchi S
Cecal Tumorigenesis in Aryl Hydrocarbon Receptor-Deficient Mice Depends on Cecum-Specific Mitogen-Activated Protein Kinase Pathway Activation and Inflammation Am J Pathol,190(2):453-468 2020 Author:Matoba H, Takamoto M, Fujii C, Kawakubo M, Kasuga E, Matsumura T, Natori T, Misawa K, Taniguchi S, Nakayama J
Bidirectional crosstalk between neutrophils and adipocytes promotes adipose tissue inflammation FASEB J,33(11):11821-11835 2019 Author:Watanabe Y, Nagai Y, Honda H, Okamoto N, Yanagibashi T, Ogasawara M, Yamamoto S, Imamura R, Takasaki I, Hara H, Sasahara M, Arita M, Hida S, Taniguchi S, Suda T, Takatsu K.
IL-1β Plays an Important Role in Pressure Overload-Induced Atrial Fibrillation in Mice Biol Pharm Bull,42(4):543-546 2019 Author:Matsushita N, Ishida N, Ibi M, Saito M, Takahashi M, Taniguchi S, Iwakura Y, Morino Y, Taira E, Sawa Y, Hirose M.
Fascin1 Suppresses RIG-I-like Receptor Signaling and Interferon-β Production by Associating with IκB Kinase ϵ (IKK ϵ) in Colon Cancer J Biol Chem,293(17):6326-6336 2018 Author:Matsumura T, Hida S, Kitazawa M, Fujii C, Kobayashi A, Takeoka M, Taniguchi SI, Miyagawa SI
Potential Role of ASC, a Proapoptotic Protein, for Determining the Cisplatin Susceptibility of Lung Cancer Cells Tohoku J Exp Med,244(2):133-144 2018 Author:Sakaizawa T, Matsumura T, Fujii C, Hida S, Toishi M, Shiina T, Yoshida K, Hamanaka K, Ito KI, Taniguchi S
The eNOS-NO pathway attenuates kidney dysfunction via suppression of inflammasome activation in aldosterone-induced renal injury model mice PLoS One,13(10):e0203823 2018 Author:Sogawa Y, Nagasu H, Itano S, Kidokoro K, Taniguchi S, Takahashi M, Kadoya H, Satoh M, Sasaki T, Kashihara N
ASC Induces Apoptosis via Activation of Caspase-9 by Enhancing Gap Junction-Mediated Intercellular Communication PLoS One,12(1):e0169340 2017 Author:Kitazawa M, Hida S, Fujii C, Taniguchi S, Ito K, Matsumura T, Okada N, Sakaizawa T, Kobayashi A, Takeoka M, Miyagawa S
In situ delivery and production system of trastuzumab scFv with Bifidobacterium Biochem Biophys Res Commun,493(1):306-312 2017 Author:Kikuchi T, Shimizu H, Akiyama Y, Taniguchi S
Novel role of ASC as a regulator of metastatic phenotype. Cancer Med. 2016 Author:Okada N, Fujii C, Matsumura T, Kitazawa M, Okuyama R, Taniguchi S, Hida S.
The endothelial adrenomedullin-RAMP2 system regulates vascular integrity and suppresses tumour metastasis. Cardiovasc Res. 2016 Author:Tanaka M, Koyama T, Sakurai T, Kamiyoshi A, Ichikawa-Shindo Y, Kawate H, Liu T, Xian X, Imai A, Zhai L, Hirabayashi K, Owa S, Yamauchi A, Igarashi K, Taniguchi S, Shindo T.
Role of NLRP3 Inflammasomes for Rhabdomyolysis-induced Acute Kidney Injury. 2015 Author:Komada T, Usui F, Kawashima A, Kimura H, Karasawa T, Inoue Y, Kobayashi M, Mizushina Y, Kasahara T, Taniguchi S, Muto S, Nagata D, Takahashi M.
Excess aldosterone is a critical danger signal for inflammasome activation in the development of renal fibrosis in mice. The FASEB Journal ,29:3899-3910 2015 Author: Kadoya H, Satoh M, Sasaki T, Taniguchi S, Takahashi M, Kashihara N
NLRP3 deficiency improves angiotensin II-induced hypertension but not fetal growth restriction during pregnancy. Endocrinology,156(11):4281-4292 2015 Author:Shirasuna K, Karasawa T, Usui F, Kobayashi M, Komada T, Kimura A, Ohkuchi A, Taniguchi S, Takahashi M.
Inflammasome activation by mitochondrial oxidative stress in macrophages leads to the development of angiotensin Ⅱ-induced aortic aneurysm. Arterioscler Thromb Vasc Biol.,35(1):127-136 2015 Author:Usui F, Shirasuna K, Kimura H, Tatsumi K, Kawashima A, Karasawa T, Yoshimura K, Aoki H, Tsutsui H, Noda T, Sagara J, Taniguchi S, Takahashi M
NFκB2 gene as a novel candidate that epigenetically responds to interval walking training. Int J Sports Med.,36(9):769-775 2015 Author:Zhang Y, Hashimoto S, Fujii C, Hida S,Ito K, Matsumura T, Sakaizawa T, Morikawa M, Masuki S, Nose H, Higuchi K, Nakajima K, Taniguchi S
Nanosilica-induced placental inflammation and pregnancy complications: Different roles of the inflammasome components NLRP3 and ASC. Nanotoxicology,9(5):554-567 2015 Author:Shirasuna1 K, Usui F , Karasawa T, Kimura H, Kawashima A, Hiroaki Mizukami H, Ohkuchi A, Nishimura S, Sagara J, Noda T, Ozawa K, Taniguchi S, Takahashi M
Phactr3/scapinin, a member of protein phosphatase 1 and actin regulator (phactr) family, interacts with the plasma membrane via basic and hydrophobic residues in the N-terminus. PLoS One,9(11):e113289 2014 Author:Itoh A, Uchiyama A, Taniguchi S, Sagara J
ビフィズス菌を利用した固形がん治療の試み Japanese Journal of Lactic Acid Bacteria,25:1 2014 Author:谷口俊一郎
ビフィズス菌を用いた抗がん剤開発 BIO INDUSTRY,31(5):43-48 2014 Author:谷口俊一郎
Nucleic acid sensing by T cells initiates Th2 cell differentiation. Nat Commun,10:3566 2014 Author:Imanishi T, Ishihara C, Badr Mel S, Hashimoto-Tane A, Kimura Y, Kawai T, Takeuchi O, Ishii KJ, Taniguchi S, Noda T, Hirano H, Brombacher F, Barber GN, Akira S, Saito T
NLRP3 Regulates Neutrophil Functions and Contributes to Hepatic Ischemia-Reperfusion Injury Independently of Inflammasomes J Immunol,192(9):4342-4351 2014 Author:Inoue Y, Shirasuna K, Kimura H, Usui F, Kawashima A, Karasawa T, Tago K, Dezaki, Nishimura S, Sagara J, Noda T, IwakuraY, Hiroko Tsutsui H, Taniguchi S, Yanagisawa K, Yada T, Yasuda Y, Takahashi M.
ASC in Renal Collecting Duct Epithelial Cells Contributes to Inflammation and Injury after Unilateral Ureteral Obstruction. American Journal of Pathology,184(5):1287-1298 2014 Author:Komada T, Usui F, Shirasuna K, Kawashima A, Kimura H, Karasawa T, Nishimura S, Sagara J, Noda T, Taniguchi S, Muto S, Nagata D, Kusano E, Takahashi M
Effect of a cholesterol-rich lipid environment on the enzymatic activity of reconstituted hyaluronan synthase Biochem. BiophysResCommun,443:666-671 2014 Author:Pawared Ontong, Hatada Y, Taniguchi S, Kakizaki I, Itano N
Beneficial innate signaling interference for antibacterial responses by a Toll-like receptor- mediated enhancement of the MKP-IRF3 axis. Proc Natl Acad SciU SA,110(49):19884-19889 2013 Author:Negishi H, Matsuki K, Endo N, Sarashina H, Miki S, Matsuda A, Fukazawa K, Taguchi-Atarashi N, Ikushima H, Yanai H, Nishio J, Honda K, Fujioka Y, Ohba Y, Noda T, Taniguchi S, Nishida E, Zhang Y, Chi H, Flavell RA, Taniguchi T.
Clinical significance of apotosis-associated speck-like protein containing a caspase recruitment domain in oral squamous cell carcinoma. Oral&Maxillofacial Pathology,115(6):799-809 2013 Author:Shimane T, Kobayashi H, Takeoka M, Kitazawa M, Matsumura T, Hida S, Tiepeng Xiao, Koike T, Taniguchi S, Kurita H.
Crucial Role of Hyaluronan in Neointimal Formation after Vascular Injury. PLOS ONE.,8(3):e58760 2013 Author:Kashima Y, Takahashi M, Shiba Y, Itano N, Izawa A, Koyama J, Nakayama J, Taniguchi S, Kimata K, Ikeda U.
ASC-associated inflammation promotes cecal tumorigenesis in aryl hydrocarbon receptor- deficient mice. Carcinogenesis.,34(1):1620-1627 2013 Author:Ikuta T, Kobayashi Y, Kitazawa M, Shiizaki K, Itano N, Noda T, Pettersson S, Poellinger L, Fujii-Kuriyama Y, Taniguchi S, Kawajiri K.
Critical role of caspase-1 in vascular inflammation and development of atherosclerosis in Western diet-fed apolipoprotein E-deficient mice. Biochem Biophys Res Commun.,425:162-168 2012 Author:Usui F, Shirasuna K, Kimura H, Tatsumi K, Kawashima A, Karasawa T, Hida S, Sagara J, Taniguchi S,Takahashi M.
ASC plays a role in the priming phase of the immune response to type II collagen in collagen-induced arthritis. Rheumatol Int.,Feb 18:Epub ahead of print 2011 Author:Yamazaki H, Takeoka M, Kitazawa M, Ehara T, Itano N, Kato H, Taniguchi S.
A novel role of Rho-kinase in the regulation of ligand-induced phosphorylated EGFR endocytosis via the early/late endocytic pathway in human fibrosarcomacells. J Mol Histol.,42:427-442 2011 Author:Nishimura Y, Biborka Bereczky, Yoshioka K, Taniguchi S, Itoh K
Inflamasome Activation of Cardiac Fibroblasts IsEssential for MyocardialIschemia/Reperfusion Injury Circulation.,123:594-604 2011 Author:Kawaguchi M, Takahashi M, Hata T, Kashima Y, Usui F, Izawa A, Takahashi Y, Masumoto J, Koyama J, Hongo M, Noda Tetsuo, Nakayama J, Sagara J, Taniguchi S, Ikeda U.
Effects of Anti-CD70 mAb on Theiler’s Murine Encephalomyelitis Virus-Induced Demyelinaiting Disease. Brain Res.,4:236-245 2010 Author:Yanagisawa S, Takeichi N, Kaneyama T, Yagita H, Taniguchi S, Byung S.Kim, Chang-Sung Koh
Pathogenic Vibrio activated NLRP3 inflammasome via cytotoxins and TLR/NOD-Mediated NF-κB signaling. J. Immunol.,184(9):5287-5297 2010 Author:Toma C, Higa N, Koizumi Y, Nakasone N, Ogura Y, McCoy AJ, Franchi L, Uematsu S, Sagara J, Taniguchi S, Tsutsui H, Akira S, Tschopp J, Núñez G, Suzuki T.
Anti-inflammatory activity of PYNOD and its mechanism in humans and mice. J Immunol.,184(10):5874-5884 2010 Author:Imamura R, Wang Y, Kinoshita T, Suzuki M, Noda T, Sagara J, Taniguchi S, Okamoto H, Suda T.
Calponin h1-S175T Point Mutation Enhances Resistance to Actin Cytoskeleton Perturbation in Human CancerCells ANTICANCER RES.,30:1071-1078 2010 Author:Sugaya A, Takeoka M, Itano N, Taguchi A, Ehara T, Taniguchi S.
Exercise Effects on Methylation of ASC Gene. IntJ Sports Med.,31(9):671-675 2010 Author:Nakajima K, Takeoka M, Mori M, Hashimoto S, Sakurai A, Nose H, Higuchi K, Itano N,Shiohara M, Oh T, Taniguchi S.
Targeting solid tumors with non-pathogenic obligate anaerobic bacteria. Cancer Sci.,101(9):1925-1932 2010 Author:Taniguchi S, Fujimori M, Sasaki T, Tsutsui H, Shimatani Y, Seki K, Amano J.
Hyaluronan Deficiency in Tumor Stroma Impairs Macrophage Trafficking and TumorNeovascularization. Cancer Res.,70(18):7073-7083 2010 Author:Kobayashi N, Miyoshi S, Mikami T, Koyama H, Kitazawa M, Takeoka M, Sano K,Amano J, Isogai Z, Niida S, Oguri K, Okayama M, John A. McDonald, Kimata K, Taniguchi S, Itano N.
A Splice Variant of ASC Regulates IL-1β Release and Aggregates Differently from Intact ASC. Mediators Inflamm.,2009:287387 2009 Author:Matsushita K, Takeoka M, Sagara J, Itano N, Kurose Y, Nakamura A, Taniguchi S.
Contribution of TIR domain-containing adapter inducing IFN-β mediated IL-18 Release to LPS-induced liver injury in mice. ,51:333-341 2009 Author:Imamura M, Tsutsui H, Yasuda K, Yumikura-Futatsugi S, Mitani K, Uchiyama R, Hayashi S, Akira S, Taniguchi S, Nico Van Rooijen, Jurg Tschopp,Yamamoto T, Fujimoto J, Nakanishi K.
Scapinin, the Protein Phosphatase 1 Binding Protein, Enhances Cell Spreading and Motility by Interacting with the Actin Cytoskeleton Plos ONE,4(1):e4247 2009 Author:Sagara J, Arata T, Taniguchi S
Role of ASC in the Mouse Model ofHelicobacter pylori Infection. J.Histochem&Cytochem.,57(4):327-338 2009 Author:Benoit BN, Kobayashi M, Kawakubo M,Takeoka M, Sano K, Zou J, Itano N, Tsutsui H, Noda T, Fukuda M, Nakayama J, Taniguchi S
Critical role of bone marrow apoptosis-associated speck-like protein, an inflammasome adaptor molecule, in neointimal formation after vascular injury inmice Circulation.,117(24):3079-3087 2008 Author:Yajima N, Takahashi M, Morimoto H, Shiba Y, Takahashi Y, Masumoto J, Ise H,Sagara J, Nakayama J, Taniguchi S, Ikeda U
Reduction of Calponin h1 expression in human colon cancer blood vessels European Journal of Surgical Oncology,34:531-537 2008 Author:Yanagisawa Y, Takeoka M, Ehara T, Itano N, Miyagawa S, Taniguchi S.
Significance of Tumor-Associated Stroma in Promotion of Intratumoral Lymphangiogenesis: Pivotal Role of a Hyaluronan-Rich Tumor Microenvironment Am. J. Pathol,172:179-193 2008 Author:Koyama H, Kobayashi N, Harada M, Takeoka M, Kawai Y, Sano K, Fujimori M, Amano, J., Ohhashi, T., Kannagi, R., Kimata, K., Taniguchi, S., and Itano, N.
Metastasis-associated gene expression profile of liver and subcutaneous lesions derived from mouse pheochromocytoma cells. Molecular Carcinogenesis,47:245-251 2008 Author:Ohta S, Taniguchi S, et al
Crosstalk between neovessels and mural cells directs the site-specific expression of J. Cell Sci.,120(9):1607-1614 2007 Author:Yana I, Sagara H, Takaki S, Takatsu K, Nakamura K, Nakao K, Katsuki M, Taniguchi S, Aoki T, Sato H, Weiss SJ, Seiki M.
Exogeneous cytosine deaminase gene expression in bifidobacterium breve Ⅰ-53-8w for tumor-targeting enzyme/prodrug therapy Biosci. Biotechnol. Biochem.,71(12):2921-2926 2007 Author:Hidaka A, Hamaji Y, Sasaki T, Taniguchi S, Fujimori M.
Regulatory molecules involved in inflammasome formation with special reference toa key mediator protein, ASC Semin Immunopathol,29(3):231-238 2007 Author:Taniguchi S, SagaraJ
Development of spontaneous optic neuropathy in NF-kBp50-deficient mice; Requirement for NF-kBp50 in ganglion cell survival Neuropath, Applied Neurobiol.,33(6):692-705 2007 Author:Takahashi Y, Katai N, Murata T, Taniguchi S, Hayashi T
In vitro expression of β-thalassemia gene(IVS1-1G>C) reveals complete inactivation of the normal5 splice site and alternative aberrant RNA splicing. Ann Clin Biochem.,44(6):573-578 2007 Author:Fujihara N, Yamauchi K, Hirota-Kawadobora M,Ishikawa S,Tozuka M, Ishii E, Katsuyama T, Nobuo Okumura, Taniguchi S
Strong Enhancement of Recombinant Cytosine Deaminase Activity in Bifidobacterium longum for Tumor Targeting Enzyme-Prodrug Therapy. Biosci. Biotechnol Biochem,71(4):874-883 2007 Author:Hamaji Y, Fujimori M, Sasaki T, MatsuhashiH, Matsui-Seki K, Shimatani-Shibata Y, Kano Y, Amano J, and Taniguchi S.
Translocation of Heparanase into Nucleus Results in Cell Differentiation. Cancer Sci.,98(4):535-540 2007 Author:Nobuhisa T, Nakamoto Y, Okawa T, Takaoka M, Gundz M, Nagatsuka H, Tsujigiwa H, Shirakawa Y, Yamatsuji T, Haisa M, , Matsuoka J, Nakajima M, Taniguchi S, Sagara J, Dong J, and Tanaka N.
Hyperproduction of Hyaluronan in Neu-Induced Mammary Tumor Acceletrates Angiogenesis through Stromal Cell Recruitment: Possible Involvement of Versican/PG-M. Am. J.Pathol.,170(3):1086-1099 2007 Author:KoyamaH; Hibi T； Isogai Z； Yoneda M；Fujimori M; Amano J; Kawakubo M; Kannagi R；Kimata K；Taniguchi S；Itano N.
Cryopyrin and pyrin activate caspase-1, but not NF-kappa B, via ASC oligomerization CELL DEATH AND DIFFERENTIATION,13(2):236-249 2006 Author:Yu, JW; Wu, J; Zhang, Z; Datta, P; Ibrahimi, I; Taniguchi, S; Sagara, J; Fernandes-Alnemri, T; Alnemri, ES
Genetically engineered Bifidobacterium longum for tumor-targeting enzyme-prodrug therapy of autochthonous mammary tumors in rats CANCER SCIENCE,97(7):649-657 2006 Author:Sasaki, T; Fujimori, M; Hamaji, Y; Hama, Y; Ito, K; Amano, J; Taniguchi, S
Hypermethylation of ASC/TMS1 is a sputum marker for late-stage lung cancer CANCER RESEARCH,66(12):6210-6218 2006 Author:Machida, EO; Brock, MV; Hooker, CM; Nakayama, J; Ishida, A; Amano, J; Picchi, MA; Belinsky, SA; Herman, JG; Taniguchi, S; Baylin, SB
Adenovirus-mediated Calponin h1 gene therapy directed against peritoneal dissemination of ovarian cancer: Bifunctional therapeutic effects on peritoneal cell layer and cancer cells CLINICAL CANCER RESEARCH,12(17):5216-5223 2006 Author:Ogura, T; Kobayashi, H; Ueoka,Y; Okugawa, K; Kato, K; Hirakawa, T; Hashimoto, S; Taniguchi, S; Wake, N;Nakano,H
Animal models of pheochromocytoma including NIH initial experience PHEOCHROMOCYTOMA,1073:300-305 2006 Author:Ohta, S; Lai, EW; Taniguchi, S; Tischler, AS; Alesci, S; Pacak, K
Genetically engineered bifidobacterium longum for tumor-targeting enzyme-prodrug therapy of breast cancer. BREAST CANCER RESEARCH ANDTREATMENT,100:S77-S77 2006 Author:Fujimori, M; Sasaki, T; Hamaji, Y; Amano, J; Taniguchi, S
Suppression of cancer phenotypes through a multifunctional actin-binding protein, calponin, that attacks cancer cells and simultaneously protects the host from invasion Cancer Science,96(11):738-746 2005 Author:Taniguchi, S
Role of charged and hydrophobic residues in the oligomerization of the PYRIN domain of ASC Biochemistry,44(2):575-583 2005 Author:Moriya M, Taniguchi S, Peter Wu, Edvards Liepinsh, Gottfried Otting, Sagara J
QT PRODACT: evaluation of the potential of compounds to cause QT interval prolongation by action potential assays using guinea-pig papillary muscles J Pharmacol Sci,99:449-457 2005 Author:Kii Y, Hayashi S, Tabo M, Shimosato T, Fukuda H, Itoh T, Amano H, Saito M, Morimoto H, YamadaK, Kanda A, Ishitsuka T,Yamazaki T, Kiuchi Y, Taniguchi S, Mori T, Shimizu S, Tsurubuchi Y, Yasuda S, Kitani S, Shimada C, Kobayashi K, Komeno M, Kasai C, Hombo T, Yamamoto K
QT PRODACT: a multi-site study of in vitro action potential assays on 21 compounds in isolated guinea-pig papillary muscles J Pharmacol Sci,99:423-437 2005 Author:Hayashi S, Kii Y, Tabo M, Fukuda H, Itoh T, Shimosato T, Amano H, Saito M, Morimoto H, Yamada K, Kanda A, Ishitsuka T, Yamazaki T, Kiuchi Y, Taniguchi S, Mori T, Shimizu S, Tsurubuchi Y, Yasuda S, Kitani S, Shimada C, Kobayashi K, Komeno M, Kasai C, Hombo T, Yamamoto K
Dihydropyrimidine dehydrogenase expressionpredicts survival outcome and chemosensitivity to 5-fluorouracil in patients with oral squamous cell carcinoma Oral Oncol,41(1):38-47 2005 Author:Kobayashi H, Koike T, Nakatsuka A, Kurita H, Sagara J, Taniguchi S, Kurashina K
ASC is essential for LPS-induced activation of procaspase-1 independently of TLR-associated signal adaptor molecules Genes to Cells,9(11):1055-1067 2004 Author:Yamamoto M, Yaginuma K, Tsutsui H, Sagara J, Guan X, Seki E, Yasuda K, Yamamoto M,AkiraS, Nakanishi K, Noda T, Taniguchi S
Selective expression and functional characteristics of three mammalian hyaluronan synthases in oncogenic malignant transformation J Biol Chem,279(18):18679-18687 2004 Author:Itano N, Sawai T, Atsumi F, Miyaishi O, Taniguchi S, Kannagi R, Hamaguchi M, Kimata K
Clinical significance of cellular distribution of moesin in patients with oral squamous cell carcinoma Clin Cancer Res,10(2):572-580 2004 Author:Kobayashi H, Sagara J, Kurita H, Morifuji M, Ohishi M, Kurashina K, Taniguchi S
H1カルポニン遺伝子欠損マウスにおける運動性ならびに摂食・飲水行動の増加(短報)(生理学) The journal of veterinary medical science,65(1):153-155 2003 Author:坂内慎，善本亮，三井-斉藤みの里，堀正敏，西原真杉，高橋克仁，山村倫子，谷口俊一郎，勝木元也，尾崎博，唐木英明
Increased locomotor activity, increased food and water intake and decreased PVN neurons in H1 calponin gene-deficient mice JOURNAL OF VETERINARYMEDICALSCIENCE,65(1):153-155 2003 Author:Bannai, M; Yoshimoto, R; Mitsui-Saito, M; Hori, M; Nishihara, M; Takahashi, K; Yamamura, H; Taniguchi, S; Katsuki, M; Ozaki, H; Karaki, H
Caspy, a zebrafish caspase, activated by ASC oligomerization is required for pharyngeal arch development JOURNAL OF BIOLOGICAL CHEMISTRY,278(6):4268-4276 2003 Author:Masumoto, J; Zhou, WB; Chen, FF; Su, FY; Kuwada, JY; Hidaka, E; Katsuyama,T; Sagara, J; Taniguchi, S;Ngo-Hazelett, P; Postlethwait, JH;Nunez, G; Inohara, N
Enhanced baroreflex sensitivity in free-moving calponin knockout mice AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY,284(3):H939-H946 2003 Author:Masuki, S; Takeoka, M; Taniguchi, S; Nose, H
ASC is an activating adaptor for NF-kappa B and caspase-8-dependent apoptosis BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS,303(1):69-73 2003 Author:Masumoto, J; Dowds, TA; Schaner, P; Chen, FF; Ogura, Y; Li, M; Zhu, L; Katsuyama, T; Sagara, J; Taniguchi, S; Gumucio, DL;Nunez, G; Inohara, N
Impaired arterial pressure regulation during exercise due to enhancedmuscular vasodilation in calponin knockout mice FASEB JOURNAL,17(4):A431-A431 2003 Author:Masuki, S; Takeoka, M; Taniguchi, S; Nose, H
Shifts in cellular localization of moesin in normal oral epithelium, oral epithelial dysplasia, verrucous carcinoma and oral squamous cell carcinoma JOURNAL OF ORAL PATHOLOGY&MEDICINE,32(6):344-349 2003 Author:Kobayashi, H; Sagara, J; Masumoto, J; Kurita, H; Kurashina, K; Taniguchi, S
Reduced expression of actin-binding proteins, h-caldesmon and calponin h1, in the vascular smooth muscle inside melanoma lesions: an adverse prognostic factor for malignant melanoma BRITISH JOURNAL OF DERMATOLOGY,148(5):971-980 2003 Author:Koganehira, Y; Takeoka, M; Ehara, T; Sasaki, K; Murata, H; Saida, T; Taniguchi, S
ASC/TMS1, A caspase-1 activating adaptor, is downregulated by aberrant methylation in human melanoma INTERNATIONAL JOURNAL OF CANCER,107(2):202-208 2003 Author:Guan, X; Sagara, J; Yokoyama, T; Koganehira, Y; Oguchi, M; Saida, T; Taniguchi, S
Suppression of peritoneal dissemination through protecting mesothelial cells from retraction by cancer cells INTERNATIONAL JOURNAL OF CANCER,107(4):557-563 2003 Author:Hashimoto, S; Takeoka, M; Taniguchi, S
Impaired arterial pressure regulation during exercise dueto enhanced muscular vasodilatation in calponin knockout mice JOURNAL OF PHYSIOLOGY-LONDON,553(1):203-212 2003 Author:Masuki, S; Takeoka, M; Taniguchi, S; Yokoyama, M; Nose, H
Methylation of ASC/TMS1, a proapoptotic gene responsible for activating procaspase-1, in human colorectal cancer CANCER LETTERS,202(1):101-108 2003 Author:Yokoyama, T; Sagara, J; Guan, X; Masumoto, J; Takeoka, M; Komiyama, Y; Miyata, K; Higuchi, K; Taniguchi, S
Scapinin, a putative protein phosphatase-1 regulatory subunit associated with the nuclear nonchromatin structure J Biol Chem,278(46):45611-45619 2003 Author:Sagara J, Higuchi T, Hattori Y, Moriya M, Sarvotham H, Shima H, Shirato H, KikuchiK,Taniguchi S
Apoptosis-associated speck-like protein is associated with inflammation and apoptosis in liver withhepatitis C infection. HEPATOLOGY,36(4):270A-270A 2002 Author:Soeda, J; Miyagawa, S; Sagara, J; Sano, K; Masumoto, J; Ichikawa, E; Taniguchi, S; Kawasaki, S
Antitumor efficacy of anaerobic bacteria as delivery system for breast cancer gene therapy. BREAST CANCER RESEARCH AND TREATMENT,76:S100-S100 2002 Author:Fujimori, M; Sasaki, T; Nakamura, T; Amano, J; Taniguchi, S
Calponin H1 induced a flattened morphology and suppressed the growth of human fibrosasrcoma HT1080 cells Eur J Cancer,38(3):436-442 2002 Author:Takeoka M, Ehara T, Hashimoto S, Taniguchi S
Expression of lamins depends on epidermal differentiation and transformation Brit.J. Dermatology,147(5):1-6 2002 Author:Oguchi M, Sagara J, Matsumoto K, Saida T, Taniguchi S
Inhibition of urokinase-type plasminogen activator delays expression of c-jun, activated transforming growth factor beta 1, and matrix metalloproteinase 2 during post-hepatectomy liver regenerationin mice J Hepatology,36(5):637-644 2002 Author:Nomura K, Miyagawa S, Ayukawa K, Soeda J, Taniguchi S, Kawasaki S
Cloned cytosine deaminase gene expression of bifidobacterium longum and application to enzyme/pro-drug therapy of hypoxic solid tumors Biosci Biotechnol Biochem,66(11):2362-2366 2002 Author:Nakamura T, Sasaki T, Fujimori M, Yazawa K, Kano Y, Amano J, Taniguchi S
The genus Bifidobacterium for cancer gene therapy Current Opinion In Drug Discovery&Development,5(2):200-203 2002 Author:Fujimori M, Amano J, Taniguchi S
ASC, which is composed of a PYD and a CARD, is up-regulated by inflammation and apoptosis in human neutrophils Biochem Biophys Res Commun,293(5):1314-1318 2002 Author:Shiohara M, Taniguchi S, Masumoto J, Yasui K, Koike K, Komiyama A, Sagara J
Calponin h1 suppresses tumor growth of src-induced transformed 3Y1 cells in association with a decrease in angiogenesis. Jpn J Cancer Res,93(8):935-943 2002 Author:Kaneko M, Takeoka M, Oguchi M, Koganehira Y, MurataH, Ehara T, Tozuka M, Saida T, Taniguchi S
Murine ortholog of ASC, a CARD-containing protein, self-associates and exhibits restricteddistribution in developing mouse embryos EXPERIMENTAL CELL RESEARCH,262(2):128-133 2001 Author:Masumoto, J; Taniguchi, S; Nakayama, K; Ayukawa, K; Sagara, J
Pyrin N-terminal homology domain- and caspase recruitment domain-dependent oligomerization of ASC BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS,280(3):652-655 2001 Author:Masumoto, J; Taniguchi, S; Sagara, J
Bifidobacterium longum as a delivery system for gene therapy of chemically induced rat mammary tumors BREAST CANCER RESEARCH AND TREATMENT,66(2):165-170 2001 Author:Yazawa, K; Fujimori, M; Nakamura,T; Sasaki, T; Amano, J; Kano, Y; Taniguchi, S
Close relation of reduced expression of actin-binding proteins, calponin-h1 and h-caldesmon, in the vascular smoothmuscle inside human malignant melanoma with the poor prognosis JOURNAL OF INVESTIGATIVE DERMATOLOGY,117(2):393-393 2001 Author:Koganehira, Y; Takeoka, T; Ehara, T; Hashimoto, S; Murata, H; Saida, T; Taniguchi,S
Expression of apoptosis-associated speck-like protein containing a caspaserecruitment domain, a pyrin N-terminal homology domain-containing protein, in normal human tissues JOURNAL OF HISTOCHEMISTRY&CYTOCHEMISTRY,49(10):1269-1275 2001 Author:Masumoto, J; Taniguchi, S; Nakayama, J; Shiohara, M; Hidaka, E; Katsuyama, T; Murase, S;Sagara, J
Urokinase-type plasminogen activator initiates expression of c-jun, activated transforming growth factor beta 1, and matrix metalloproteinase 2 during post-hepatectomy liver regeneration in mice. HEPATOLOGY,34(4):387A-387A 2001 Author:Nomura, K; Miyagawa, S; Ayukawa, K; Soeda, J; Taniguchi, SI; Kawasaki, S
Initiation of apoptotic cascade during warm ischemia in rat liver. HEPATOLOGY,34(4):275A-275A 2001 Author:Soeda, J; Miyagawa, S; Sano, K; Masumoto, S; Taniguchi, S; Kawasaki, S
Cytochrome c release into cytosol with subsequent caspase activation during warm ischemia in rat liver AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY,281(4):G1115-G1123 2001 Author:Soeda, J; Miyagawa, S; Sano, K; Masumoto, J; Taniguchi, S; Kawasaki, S
Dynamic DNA methylation change in the CpGisland region of p15 during human myeloid development JOURNAL OF CLINICAL INVESTIGATION,108(8):1195-1204 2001 Author:Sakashita, K; Koike, K; Kinoshita, T; Shiohara, M; Kamijo, T; Taniguchi, S; Kubota, T
Bifidobacterium longum as a delivery system for gene therapy of chemically induced rat mammary tumors. BREAST CANCER RESEARCH AND TREATMENT,69(3):256-256 2001 Author:Fujimori, M; Nakamura, T; Sasaki, T; Hama, Y; Amano, J; Taniguchi, S
ASC, which is composed of a pyrin-N-terminal homology domain and a caspase-recruitment domain, is up-regulated by inflammation and apoptosis in human neutrophils. BLOOD,98(11):229A-229A 2001 Author:Shiohara, M; Taniguchi, S; Masumoto, J; Yasui, K; Koike, K; Komiyama, A; Sagara, J
Structural fragility of blood vessels and peritoneum in calponin h1-deficientmice, resulting in an increase in hematogenous metastasis and peritoneal dissemination of malignant tumor cells CANCER RESEARCH,61(20):7627-7634 2001 Author:Taniguchi, S; Takeoka, M; Ehara, T; Hashimoto, S; Shibuki, H; Yoshimura, N; Shigematsu, H; Takahashi, K; Katsuki, M
Bifidobacterium longum as a delivery system for cancer gene therapy: Selective localization and growth in hypoxic tumors CANCER GENE THERAPY,7(2):269-274 2000 Author:Yazawa, K; Fujimori, M; Amano, J; Kano, Y; Taniguchi, S
Sequential chemoimmunotherapy with cisplatin, interferon-beta and interleukin-2 inhibits the growth of B16-F1 melanoma in syngeneic mice MELANOMA RESEARCH,10(3):223-229 2000 Author:Kubo, H; Matsumoto, K; Funahashi, M; Takagi, H; Kitajima, Y; Taniguchi, S; Saida, T
Human malignant melanoma cells release a factor that inhibits the expressionof smooth muscle alpha-actin JOURNAL OF DERMATOLOGICAL SCIENCE,23(3):170-177 2000 Author:Okamoto-Inoue, M; Nakayama, J; Hori, Y; Taniguchi, S
Regulation of shortening velocity by calponin in intact contracting smooth muscles BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS,279(1):150-157 2000 Author:Takahashi, K; Yoshimoto, R; Fuchibe, K; Fujishige, A; Mitsu-Saito, M; Hori, M; Ozaki, H; Yamamura, H; Awata, N; Taniguchi, S; Katsuki, M; Tsuchiya, T; Karaki, H
Ca2+-sensitization of contraction in the h1 calponin-deficient smooth muscle JAPANESE JOURNAL OF PHARMACOLOGY,84(4):474-475 2000 Author:Yoshimoto, R; Hori, M; Takahashi, K; Taniguchi, S; Katsuki, M; Ozaki, H; Karaki, H
Contractile properties and proteins of smooth muscles of a calponin knockout mouse JOURNAL OF PHYSIOLOGY-LONDON,529(3):811-824 2000 Author:Matthew, JD; Khromov, AS; McDuffie, MJ; Somlyo, AV; Somlyo, AP; Taniguchi, S; Takahashi, K
Bifidobacterium longum as a delivery system for cancer gene therapy: selective localization and growth in hypoxic tumors Cancer Gene Therapy,7(2):269-274 2000 Author:K Yazawa, M Fujimori, J Amano, Y Kano, S Taniguchi
La autoantigen is cleaved in the COOH terminus and loses the nuclear localization signal during apoptosis JOURNALOF BIOLOGICAL CHEMISTRY,275(44):34465-34470 2000 Author:Ayukawa, K; Taniguchi, S; Masumoto, J; Hashimoto, S; Sarvotham, H; Hara, A;Aoyama, T; Sagara, J
Promoted dermal fibrosis during wound healing in calponin h 1 (CNhl)-deleted mice JOURNAL OF INVESTIGATIVE DERMATOLOGY,112(4):583-583 1999 Author:Takeoka, M; Ehara, T; Murata, H; Saida, T; Katsuki,M; Takahashi, K; Taniguchi, S
Reduced expression of an actin binding protein, calponin h 1 (CNh1), in blood vessels of human malignant skin tumors JOURNAL OFINVESTIGATIVE DERMATOLOGY,112(4):569-569 1999 Author:Koganehira, Y; Ehara, T; Takeoka, M; Saida, T; Taniguchi, S
Inhibitory effects of roxithromycin on tumor angiogenesis, growth and metastasis of mouse B16 melanoma cells CLINICAL&EXPERIMENTAL METASTASIS,17(2):119-124 1999 Author:Yatsunami, J; Tsuruta, N; Fukuno, Y; Kawashima,M; Taniguchi, S; Hayashi, S
The induction of smooth muscle alpha actin in a transformed rat cell line suppresses malignant properties in vitro and in vivo CANCER LETTERS,142(2):173-178 1999 Author:Okamoto-Inoue, M; Kamada, S; Kimura, G; Taniguchi, S
Antiangiogenic and antitumor effects of 14-membered ring macrolides on mouse B16 melanoma cells CLINICAL&EXPERIMENTAL METASTASIS,17(4):361-367 1999 Author:Yatsunami, J; Fukuno, Y; Nagata, M; Tominaga, M; Aoki, S; Tsuruta, N; Kawashima, M; Taniguchi, S; Hayashi, S
Roxithromycin and clarithromycin, 14-membered ring macrolides, potentiate the antitumor activity of cytotoxic agents against mouse B16melanoma cells CANCER LETTERS,147(1-2):17-24 1999 Author:Yatsunami, J; Fukuno, Y; Nagata, M; Tsuruta, N; Aoki, S; Tominaga, M; Kawashima, M; Taniguchi, S; Hayashi, S
Increased synthesis of hyaluronate enhances motility of human melanoma cells JOURNAL OF INVESTIGATIVE DERMATOLOGY,113(6):935-939 1999 Author:Ichikawa, T; Itano, N; Sawai, T; Kimata, K; Koganehira, Y; Saida, T; Taniguchi, S
Possible role of calponin h1 as a tumor suppressor in human uterine leiomyosarcoma JOURNAL OF THE NATIONAL CANCER INSTITUTE,91(9):790-796 1999 Author:Horiuchi, A; Nikaido, T; Taniguchi, S; Fujii, S
ASC, a novel 22-kDa protein, aggregates during apoptosis of human promyelocytic leukemia HL-60 cells JOURNAL OF BIOLOGICAL CHEMISTRY,274(48):33835-33838 1999 Author:Masumoto, J; Taniguchi, S; Ayukawa, K; Sarvotham, H; Kishino, T; Niikawa, N; Hidaka, E; Katsuyama, T; Higuchi, T; Sagara, J
Moesin and CD44 expression in cutaneous melanocytic tumours BRITISH JOURNAL OFDERMATOLOGY,138(5):763-768 1998 Author:Ichikawa, T; Masumoto, J; Kaneko, M; Saida, T; Sagara, J; Taniguchi, S
Targeted disruption of calponin results in rapid crossbridge cycling and reduced force in phasic smooth muscle BIOPHYSICAL JOURNAL,74(2):A38-A38 1998 Author:Takahashi, K; Mitsui-Saito, M; Fuchibe, K; Yamamura, H; Taniguchi, S; Katsuki, M; Ozaki, H; Tsuchiya, T; Shibata, N; Karaki, H
Differential expression of moesin in cells of hematopoietic lineage and lymphatic systems HISTOCHEMISTRY AND CELL BIOLOGY,110(1):33-41 1998 Author:Masumoto,J; Sagara, J; Hayama, M; Hidaka, E; Katsuyama, T; Taniguchi, S
Expression of moesin and its associated molecule CD44 in epithelial skin tumors JOURNAL OF CUTANEOUS PATHOLOGY,25(5):237-243 1998 Author:Ichikawa, T; Masumoto, J; Kaneko, M; Saida, T; Sagara, J; Taniguchi, S
Reduced expression of calponin h1 in leiomyosarcoma of the uterus LABORATORY INVESTIGATION,78(7):839-846 1998 Author:Horiuchi, A; Nikaido, T; Ito, K;Zhai, YI; Orii, A; Taniguchi, S; Toki, T; Fujii, S
Augmentation in the expression of a ribosomal protein associated with transformation BIOCHEMISTRY AND MOLECULAR BIOLOGY INTERNATIONAL,46(3):629-638 1998 Author:Go, H; Taniguchi, S
Genomic structure of the human ribosomalprotein L41 gene BIOCHEMISTRY AND MOLECULAR BIOLOGY INTERNATIONAL,46(6):1227-1231 1998 Author:Go, H; Miyado, K; Taniguchi, S
Mice lackingsmooth muscle calponin display increased bone formation that is associated with enhancement of bone morphogenetic protein responses GENES TO CELLS,3(10):685-695 1998 Author:Yoshikawa, H; Taniguchi, S; Yamamura, H; Mori, S; Sugimoto, M; Miyado, K; Nakamura, K; Nakao, K; Katsuki, M; Shibata, N; Takahashi, K
A BALB/c 3T3-transformed cell line suitable for transfection assay of metastasis-inducing genes INTERNATIONAL JOURNAL OF CANCER,71(1):88-93 1997 Author:Tatsuka, M; Ota, T; Maeda, M; Wada, M; Yamagishi, N; Taniguchi, S;Seiki, M; Odashima, S
Transformation-related expression of a low-molecular-mass tropomyosinisoform TM5/TM30nm in transformed rat fibroblastic cell lines JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY,123(6):331-336 1997 Author:Miyado, K; Sato, M; Taniguchi, S
Suppression of pulmonary metastasis in murine B16 melanoma cells by transfection of a sialidase cDNA INTERNATIONAL JOURNAL OFCANCER,73(3):410-415 1997 Author:Tokuyama, S; Moriya, S; Taniguchi, S; Yasui, A; Miyazaki, J; Orikasa, S; Miyagi, T
Dibutyryl cAMP inhibits endotoxin-induced increases in pulmonary vascular resistance and fluid filtration coefficient in the perfused rat lung TOHOKU JOURNAL OF EXPERIMENTAL MEDICINE,183(4):273-284 1997 Author:Takeoka, M; Sakai, A; Ueda, G; Ge, RL; Ishizaki, T; Panos, RJ; Taniguchi, S
Decreased expression of a single tropomyosin isoform, TM5/TM30nm, results in reduction in motility of highly metastatic B16-F10 mouse melanoma cells BIOCHEMICAL AND BIOPHYSICAL RESEARCHCOMMUNICATIONS,225(2):427-435 1996 Author:Miyado, K;Kimura, M; Taniguchi, S
Influence of hypoxia and pulmonary air embolism on lung injury in perfused rat lungs RESPIRATION,63(6):346-351 1996 Author:Takeoka, M; Sakai, A; Ueda, G;Ge, RL; Panos, RJ; Taniguchi, S
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