森 琢磨 (モリ タクマ)
学術研究院（医学系）
先鋭領域融合研究群 バイオメディカル研究所
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研究活動情報
論文
- CASK異常症モデル動物を用いた多階層解析：タンパク質構造から社会行動までをAI技術を用いて解析する
森 琢磨
信州医学雑誌, 72(3), 131-140, 2024年
- Deep-Learning-Based Analysis Reveals a Social Behavior Deficit in Mice Exposed Prenatally to Nicotine
M. Zhou, W. Qiu, N. Ohashi, L. Sun, M. L. Wronski, E. Kouyama-Suzuki Y. Shirai, T. Yanagawa, T. Mori, and K. Tabuchi
Cells, 13(3), 275, 2024年, 査読有り, 招待無し
責任著者 - Diverse pathological phenotypes of CASK-related disorders and multiple functional domains of CASK protein.
T. Mori M. Zhou and K. Tabuchi.
Genes, 14(8), 1656, 2023年, 査読有り
筆頭著者, 責任著者 - Structural Analysis Implicates CASK-Liprin-α2 Interaction in Cerebellar Granular Cell Death in MICPCH Syndrome.
29. Q. Guo, E. Kouyama-Suzuki, Y. Shirai, X. Cao, T. Yanagawa, T. Mori and K. Tabuchi.
Cells, 12(8), 1177, 2023年, 査読有り - An epilepsy-associated mutation of salt-inducible kinase 1 increases the susceptibility to epileptic seizures and interferes with adrenocorticotropic hormone therapy for infantile spasms in mice.
B. Pang, T. Mori, M. Badawi, M. Zhou, Q. Guo, E. Suzuki-Kouyama, T. Yanagawa, Y. Shirai, and K. Tabuchi
International Journal of Molecular Sciences, 23, 7927, 2022年, 査読有り
筆頭著者, 責任著者 - IQSEC3 Deletion Impairs Fear Memory Through Upregulation of Ribosomal S6K1 Signaling in the Hippocampus
Kim, Dongwook; Jung, Hyeji; Shirai, Yoshinori; Kim, Hyeonho; Kim, Jinhu; Lim, Dongseok; Mori, Takuma; Lee, Hyojeong; Park, Dongseok; Kim, Hee Young; Guo, Qi; Pang, Bo; Qiu, Wen; Cao, Xueshan; Kouyama-Suzuki, Emi; Uemura, Takeshi; Kasem, Enas; Fu, Yu; Kim, Seungjoon; Tokunaga, Akinori; Yoshizawa, Takahiro; Suzuki, Tatsuo; Sakagami, Hiroyuki; Lee, Kea Joo; Ko, Jaewon; Tabuchi, Katsuhiko; Um, Ji Won;
BIOLOGICAL PSYCHIATRY, 91(9), 821-831, 2022年
- IQSEC2 Deficiency Results in Abnormal Social Behaviors Relevant to Autism by Affecting Functions of Neural Circuits in the Medial Prefrontal Cortex
Mehta, Anuradha; Shirai, Yoshinori; Kouyama-Suzuki, Emi; Zhou, Mengyun; Yoshizawa, Takahiro; Yanagawa, Toru; Mori, Takuma; Tabuchi, Katsuhiko;
CELLS, 10(10), 2724, 2021年10月 - Inhibition of CASK Expression by Virus-mediated RNA Interference in Medial Prefrontal Cortex Affects Social Behavior in the Adult Mouse
Xueshan, Cao; Wen, Qiu; Bo, Pang; Mengyun, Zhou; Anuradha, Mehta; Qi, Guo; Shirai, Yoshinori; Mori, Takuma; Tabuchi, Katsuhiko
信州医学雑誌, 69(1), 45-52, 2021年02月10日
- Npas4 regulates IQSEC3 expression in hippocampal somatostatin interneurons to mediate anxiety-like behavior
Kim, Seungjoon; Park, Dongseok; Kim, Jinhu; Kim, Dongwook; Kim, Hyeonho; Mori, Takuma; Jung, Hyeji; Lee, Dongsu; Hong, Sookyung; Jeon, Jongcheol; Tabuchi, Katsuhiko; Cheong, Eunji; Kim, Jaehoon; Um, Ji Won; Ko, Jaewon;
CELL REPORTS, 36(3), 2021年 - Risperidone Mitigates Enhanced Excitatory Neuronal Function and Repetitive Behavior Caused by an ASD-Associated Mutation of SIK1
Badawi, Moataz; Mori, Takuma; Kurihara, Taiga; Yoshizawa, Takahiro; Nohara, Katsuhiro; Kouyama-Suzuki, Emi; Yanagawa, Toru; Shirai, Yoshinori; Tabuchi, Katsuhiko;
FRONTIERS IN MOLECULAR NEUROSCIENCE, 14, 2021年 - Efferent and Afferent Connections of Neuropeptide Y Neurons in the Nucleus Accumbens of Mice
Yamada, Shunji; van Kooten, Nienke; Mori, Takuma; Taguchi, Katsutoshi; Tsujimura, Atsushi; Tanaka, Masaki;
FRONTIERS IN NEUROANATOMY, 15, 741868, 2021年 - DNA repair protein RAD51 enhances the CRISPR/Cas9-mediated knock-in efficiency in brain neurons
Kurihara, Taiga; Kouyama-Suzuki, Emi; Satoga, Michiru; Li, Xue; Badawi, Moataz; Thiha; Baig, Deeba Noreen; Yanagawa, Toru; Uemura, Takeshi; Mori, Takuma; Tabuchi, Katsuhiko;
Biochemical and biophysical research communications, 524(3), 621-628, 2020年 - Inhibition of DNA ligase IV enhances the CRISPR/Cas9-mediated knock-in efficiency in mouse brain neurons
Cao, Xueshan; Kouyama-Suzuki, Emi; Pang, Bo; Kurihara, Taiga; Mori, Takuma; Yanagawa, Toru; Shirai, Yoshinori; Tabuchi, Katsuhiko;
Biochemical and biophysical research communications, 533(3), 449-457, 2020年 - Deficiency of calcium/calmodulin-dependent serine protein kinase disrupts the excitatory-inhibitory balance of synapses by downregulating GluN2B (vol 24, pg 1079, 2019)
Mori, Takuma; Kasem, Enas A.; Suzuki-Kouyama, Emi; Cao, Xueshan; Li, Xue; Kurihara, Taiga; Uemura, Takeshi; Yanagawa, Toru; Tabuchi, Katsuhiko;
MOLECULAR PSYCHIATRY, 24(7), 1093-1093, 2019年07月 - Length of myelin internodes of individual oligodendrocytes is controlled by microenvironment influenced by normal and input-deprived axonal activities in sensory deprived mouse models
Osanai, Yasuyuki; Shimizu, Takeshi; Mori, Takuma; Hatanaka, Nobuhiko; Kimori, Yoshitaka; Kobayashi, Kenta; Koyama, Shinsuke; Yoshimura, Yumiko; Nambu, Atsushi; Ikenaka, Kazuhiro;
GLIA, 66(11), 2514-2525, 2018年11月 - Higher primate-like direct corticomotoneuronal connections are transiently formed in a juvenile subprimate mammal
Murabe, Naoyuki; Mori, Takuma; Fukuda, Satoshi; Isoo, Noriko; Ohno, Takae; Mizukami, Hiroaki; Ozawa, Keiya; Yoshimura, Yumiko; Sakurai, Masaki;
SCIENTIFIC REPORTS, 8, 2018年 - Rabies Virus-Mediated Oligodendrocyte Labeling Reveals a Single Oligodendrocyte Myelinates Axons from Distinct Brain Regions
Osanai, Yasuyuki; Shimizu, Takeshi; Mori, Takuma; Yoshimura, Yumiko; Hatanaka, Nobuhiko; Nambu, Atsushi; Kimori, Yoshitaka; Koyama, Shinsuke; Kobayashi, Kenta; Ikenaka, Kazuhiro;
GLIA, 65(1), 93-105, 2017年01月 - Fluorescent protein tagging of endogenous protein in brain neurons using CRISPR/Cas9-mediated knock-in and in utero electroporation techniques
Uemura, Takeshi; Mori, Takuma; Kurihara, Taiga; Kawase, Shiori; Koike, Rie; Satoga, Michiru; Cao, Xueshan; Li, Xue; Yanagawa, Toru; Sakurai, Takayuki; Shindo, Takayuki; Tabuchi, Katsuhiko;
SCIENTIFIC REPORTS, 6, 2016年 - IQ Motif and SEC7 Domain-containing Protein 3 (IQSEC3) Interacts with Gephyrin to Promote Inhibitory Synapse Formation
Um, Ji Won; Choii, Gayoung; Park, Dongseok; Kim, Dongwook; Jeon, Sangmin; Kang, Hyeyeon; Mori, Takuma; Papadopoulos, Theofilos; Yoo, Taesun; Lee, Yeunkum; Kim, Eunjoon; Tabuchi, Katsuhiko; Ko, Jaewon;
JOURNAL OF BIOLOGICAL CHEMISTRY, 291(19), 10119-10130, 2016年 - Rabies virus glycoprotein variants display different patterns in rabies monosynaptic tracing
Mori, Takuma; Morimoto, Kinjiro;
FRONTIERS IN NEUROANATOMY, 7, 2014年 - New Rabies Virus Variants for Monitoring and Manipulating Activity and Gene Expression in Defined Neural Circuits
Osakada, Fumitaka; Mori, Takuma; Cetin, Ali H.; Marshel, James H.; Virgen, Beatriz; Callaway, Edward M.;
NEURON, 71(4), 617-631, 2011年 - Targeting Single Neuronal Networks for Gene Expression and Cell Labeling In Vivo
Marshel, James H.; Mori, Takuma; Nielsen, Kristina J.; Callaway, Edward M.;
NEURON, 67(4), 562-574, 2010年 - Expression of FOXP2 in the developing monkey forebrain: Comparison with the expression of the genes FOXP1, PBX3, and MEIS2
Takahashi, Kaoru; Liu, Fu-Chin; Oishi, Takao; Mori, Takuma; Higo, Noriyuki; Hayashi, Motoharu; Hirokawa, Katsuiku; Takahashi, Hiroshi;
JOURNAL OF COMPARATIVE NEUROLOGY, 509(2), 180-189, 2008年 - Monosynaptic restriction of transsynaptic tracing from single, genetically targeted neurons
Wickersham, Ian R.; Lyon, David C.; Barnard, Richard J. O.; Mori, Takuma; Finke, Stefan; Conzelmann, Karl-Klaus; Young, John A. T.; Callaway, Edward M.;
NEURON, 53(5), 639-647, 2007年 - Heterogeneity of the developmental patterns of neurotrophin protein levels among neocortical areas of macaque monkeys
Mori, Takuma; Takumi, Ken; Shimizu, Keiko; Oishi, Takao; Hayashi, Motoharu;
EXPERIMENTAL BRAIN RESEARCH, 171(1), 129-138, 2006年05月
