所属学会 日本病理学会 日本癌学会 日本臨床細胞学会 日本組織細胞化学会 日本分子腫瘍マーカー研究会 日本消化器癌発生学会 日本臨床検査医学会 日本神経学会 日本生化学会 日本糖質学会 日本内科学会 日本神経病理学会 日本小児病理研究会 日本がん転移学会 American Association for Cancer Research The American Society for Cell Biology The Histochemical Society
書籍等出版物 Gastric cancer, Glycoscience: Basic Science to Applications – Insights from the Japan Consortium for Glycobiology and Glycotechnology, 303-304 Springer-Nature Singapore 2019 Author:Nakayama J
Function of unique O-glycan structures in protecting gastric mucosa against Helicobacter pylori infection and gastric cancer development, Glycosignals in Cancer: Mechanisms of Malignant Phenotypes , 111-124 Springer Japan 2016 Author:Nakayama J
Helicobacter pylori, Glycoscience: Biology and Medicine , 723-729 Springer Japan 2014 Author:Kawakubo M, Ito Y, Fukuda M, Nakayama J
Alpha-1,4-N-acetylglucosaminyltransferase (A4GNT), Handbook of Glycosyltransferases and Related Genes, 2nd ed. , 379-391 Springer Japan 2014 Author:Nakayama J
ST8Sia-IV (PST-1), Taniguchi N, Honke K, Fukuda M eds: Handbook of Glycosyltransferases and Related Genes , 340-346 2002 Author:Nakayama J, Angata K, Suzuki M, Fukuda M
MUC6 expression is a preferable prognostic marker for invasive mucinous adenocarcinoma of the lung. Histochem Cell Biol,157:671-684 2022 Author:Yamanoi K, Fujii C, Yuzuriha H, Kumazawa M, Shimoda M, Emoto K, Asamura H, Nakayama J
Mucin distribution in bronchiolar adenoma/ciliated muconodular papillary tumor reveals organoid differentiation simulating the normal lung. Pathol Int ,72:300-306 2022 Author:Matoba H, Ikeyama M, Kobayashi N, Takemura H, Hanaoka T, Sato Y, Nakayama J
Acidic activated charcoal prevents obesity and insulin resistance in high-fat diet-fed mice. Front Nutr,9:852767 2022 Author:Zhang X, Diao P, Yokoyama H, Inoue Y, Tanabe K, Hayashi C, Yokoyama T, Zhang Z, Hu X, Nakajima T, Kimura T, Nakayama J, Nakamuta M, Tanaka N
Glycosylation of MUC6 by α1,4-linked N-acetylglucosamine enhances suppression of pancreatic cancer malignancy. Cancer Sci,113:576-586 2022 Author:Yuki A, Fujii C, Yamanoi K, Matoba H, Harumiya S, Kawakubo M, Nakayama J
Decreased gastric gland mucin-specific O-glycans are involved in the progression of ovarian primary mucinous tumours. Acta Histochem Cytochem,54:115-122 2021 Author:Ohya A, Matoba H, Fujinaga Y, Nakayama J
Effects of orally administered Euglena gracilis and its reserve polysaccharide, paramylon, on gastric dysplasia in A4gnt knockout mice. Sci Rep,11:13640 2021 Author:Iida M, Desamero MJ, Yasuda K, Nakashima A, Suzuki K, Chambers JK, Uchida K, Ogawa R, Hachimura S, Nakayama J, Kyuwa S, Miura K, Kakuta S, Hirayama K
Cholestenone functions as an antibiotic against Helicobacter pylori by inhibiting biosynthesis of the cell wall component CGL. Proc Natl Acad Sci USA,118:e2016469118 2021 Author:Kobayashi J, Kawakubo M, Fujii C, Arisaka N, Miyashita M, Sato Y, Komura H, Matoba H, Nakayama J
Systematic investigation of the skin in Chst14-/- mice: a model for skin fragility in musculocontractural Ehlers-Danlos syndrome caused by CHST14 variants (mcEDS-CHST14). Glycobiology ,31:137-150 2021 Author:Hirose T, Mizumoto S, Hashimoto A, Takahashi Y, Yoshizawa T, Nitahara-Kasahara Y, Takahashi N, Nakayama J, Takehana K, Okada T, Nomura Y, Yamada S, Kosho T, Watanabe T
Decreased alpha-1,4-linked N-acetylglucosamine glycosylation in biliary tract cancer progression from biliary intraepithelial neoplasia to invasive adenocarcinoma. Cancer Sci,111:4629-4635 2020 Author:Okumura M, Yamanoi K, Uehara T, Nakayama J
Overcoming the blood-brain-barrier by Annexin A1-binding peptide to target brain tumors. Brit J Cancer,123:1633-1643 2020 Author:Nonaka M, Suzuki-Anekoji M, Nakayama J, Mabashi-Asazuma H, Jarvis DL, Yeh J, Yamasaki K, Akama TO, Huang C, Campos AR, Nagaoka M, Sasai T, Kimura-Takagi I, Suwa Y, Yaegashi T, Shibata TK, Sugihara K, Nishizawa-Harada C, Fukuda M, Fukuda MN
A saturated fatty acid-rich diet enhances hepatic lipogenesis and tumorigenesis in HCV core gene transgenic mice. J Nutr Biochem,85:108460 2020 Author:Diao P, Wang X, Jia F, Kimura T, Hu X, Shirotori S, Nakamura I, Sato Y, Nakayama J, Moriya K, Koike K, Gonzalez FJ, Aoyama T, Tanaka N
Diffuse MIST1 expression and decreased α1,4-linked N-acetylgludosamine (αGlcNAc) glycosylation on MUC6 are distinct hallmarks for gastric neoplasms showing oxyntic gland differentiation. Histopathology ,77:413-422 2020 Author:Yamada S, Yamanoi K, Sato Y, Nakayama J
Polyunsaturated fatty acid deficiency affects sulfatides and other sulfated glycans in lysosomes through autophagy-mediated degradation. FASEB J,34:9594-9614 2020 Author:Wang Y, Nakajima T, Diao P, Yamada Y, Nakamura K, Nakayama J, Tanaka N, Aoyama T, Kamijo Y
Dietary restriction suppresses steatosis-associated hepatic tumorigenesis in HCV core gene transgenic mice. Liver Cancer ,9:529-548 2020 Author:Jia F, Diao P, Wang X, Hu X, Kimura T, Nakamuta M, Nakamura I, Shirotori S, Sato Y, Nakayama J, Moriya K, Koike K, Gonzalez FJ, Aoyama T, Naoki Tanaka N
Cecal tumorigenesis in aryl hydrocarbon receptor-deficient mice depends on cecum-specific mitogen-activated protein kinase pathway activation and inflammation. Am J Pathol ,190:453-468 2020 Author:Matoba H, Takamoto M, Fujii C, Kawakubo M, Kasuga E, Matsumura T, Natori T, Misawa K, Taniguchi S, Nakayama J
A trans-fatty acid-rich diet promotes liver tumorigenesis in HCV core gene transgenic mice. Carcinogenesis,41:159-170 2020 Author:Hu X, Wang X, Jia F, Tanaka N, Kimura T, Nakajima T, Sato Y, Moriya K, Koike K, Gonzalez FJ, Nakayama J, Aoyama T
Tumor-suppressing potential of stingless bee propolis in in vitro and in vivo models of differentiated-type gastric adenocarcinoma. Sci Rep,9:19635 2019 Author:Desamero MJ, Kakuta S, Tang Y, Chambers JK, Uchida K, Estacio MA, Cervancia C, Kominami Y, Ushio H, Nakayama J, Nakayama H, Kyuwa S
αGlcNAc and its catalyst α4GnT are diagnostic and prognostic markers in uterine cervical tumor, gastric type. Sci Rep,9:13043 2019 Author:Ida K, Yamanoi K, Asaka S, Takeuchi H, Miyamoto T, Shiozawa T, Nakayama J
TAK1 safeguards macrophages against proinflammatory cell death. J Immunol,203:783-788 2019 Author:Sanjo H, Nakayama J, Yoshizawa T, Fehling HJ, Akira S, Taki S
Analysis of A4gnt knockout mice reveals an essential role for gastric sulfomucins in preventing gastritis cystica profunda. J Histochem Cytochem,67:759-770 2019 Author:Kawakubo M, Komura H, Goso Y, Okumura M, Sato Y, Fujii C, Miyashita M, Arisaka N, Harumiya S, Yamanoi K, Yamada S, Kakuta S, Kawashima H, Fukuda MN, Fukuda M, Nakayama J
A high-cholesterol diet promotes steatohepatitis and liver tumorigenesis in HCV core gene transgenic mice. Arch Toxicol,93:1713-1725 2019 Author:Wang X, Tanaka N, Hu X, Kimura T, Lu Y, Jia F, Sato Y, Nakayama J, Moriya K, Koike, K, Aoyama T
Structural alteration of glycosaminoglycan side chains and spatial disorganization of collagen networks in the skin of patients with mcEDS-CHST14. Biochim Biophys Acta Gen Subj,1863:623-631 2019 Author:Hirose T, Takahashi N, Tangkawattana P, Minaguchi J, Mizumoto S, Yamada S, Miyake N, Hayashi S, Hatamochi A, Nakayama J, Yamaguchi T, Hashimoto A, Nomura Y, Takehana K, Kosho T, Watanabe T
Annexin A1 expression is correlated with malignant potential of renal cell carcinoma. Int J Urol,26:284-290 2019 Author:Yamanoi M, Fujii C, Yamanoi K, Fukuda MN, Nakayama J
Spinal manifestations in 12 patients with musculocontractural Ehlers-Danlos syndrome caused by CHST14/D4ST1 deficiency (mcEDS-CHST14). Am J Med Genet,176A:2331-2341 2018 Author:Uehara M, Kosho T, Yamamoto N, Takahashi HE, Shimakura T, Nakayama J, Kato H, Takahashi J
Gastric gland mucin-specific O-glycan expression decreases as tumor cells progress from lobular endocervical gland hyperplasia to cervical mucinous carcinoma, gastric type. Virchows Arch,473:305-311 2018 Author:Yamanoi K, Ishii K, Tsukamoto M, Asaka S, Nakayama J
Reduced αGlcNAc glycosylation on gastric gland mucin is a biomarker of malignant potential for gastric cancer, Barrett’s adenocarcinoma, and pancreatic cancer. Histochem Cell Biol,149:569-575 2018 Author:Yamanoi K, Nakayama J
Upregulated expression of La ribonucleoprotein domain family member 6 and collagen type I gene following water-filtered broad-spectrum near-infrared irradiation in a 3-dimensional human epidermal tissue culture model as revealed by microarray analysis. Australas J Dermatol,59:e87-e92 2018 Author:Tanaka Y, Nakayama J
Orally administrated brown seaweed-derived β-glucan effectively restrained development of gastric dysplasia in A4gnt KO mice that spontenously develop gastric adenocarcinoma. Int Immunopharmacol,60:211-220 2018 Author:Desamero MJ, Kakuta S, Chambers JK, Uchida K, Hachimura S, Takamoto M, Nakayama J, Nakayama H, Kyuwa S
Increased expression of Y-box-binding protein-1 in hind-limb muscles during regeneration from ischemic injury in mice. Tohoku J Exp Med ,244:53-62 2018 Author:Fuke M, Narita M, Wada Y, Seto T, Okada K, Nakayama J, Izumi H, Ito K-i
Pulmonary adenocarcinoma possibly developed from the cut-end of small-sized adenocarcinoma in the lung periphery as recurrence 13 years after its wedge resection. Surg Case Rep,4:2 2018 Author:Hanaoka T, Kurai M, Okada M, Ishizone S, Karasawa F, Iizuka A, Ikeyama M, Nakayama J
Osteosarcoma arising in fibrous dysplasia, confirmed by mutational analysis of GNAS gene. Pathol Res Pract ,214:318-324 2018 Author:Sugiura Y, Kanda H, Motoi N, Nomura K, Inamura K, Okada E, Matsumoto H, Shimoji T, Matsumoto S, Nakayama J, Takazawa Y, Ishikawa Y, Machinami R
Vascular abnormalities in the placenta of Chst14-/- fetuses: implications in the pathophysiology of perinatal lethality of the murine model and vascular lesions in human CHST14/D4ST1 deficiency. Glycobiology ,28:80-89 2018 Author:Yoshizawa T, Mizumoto S, Takahashi Y, Shimada S, Sugahara K, Nakayama J, Takeda S, Nomura Y, Nitahara-Kasahara Y, Okada T, Matsumoto K, Yamada S, Kosho T
Cholesterol-α-glucosyltransferase gene is present in most Helicobacter species including gastric non-Helicobacter pylori helicobacters obtained from Japanese patients. Helicobacter ,23:e12449 2018 Author:Kawakubo M, Horiuchi K, Matsumoto T, Nakayama J, Akamatsu T, Katsuyama T, Ota H, Sagara J
Reversion-Inducing cysteine-rich protein with Kazal motifs (RECK) in angiogenesis of microvessels in glioblastoma. J Clin Mol Pathol ,1:No.2:12 2017 Author:Kanaya K, Sakai K, Hongo K, Fukushima M, Kawakubo M, Nakayama J
Interleukin-17A-deficient mice are highly susceptible to Toxoplasma gondii infection due to excessively induced T. gondii HSP70 and interferon gamma poduction. Infect Immun,85:e00399-17 2017 Author:Moroda M, Takamoto M, Iwakura Y, Nakayama J, Aosai F
Cloning of Helicobacter suis cholesterol α-glucosyltransferase and production of an antibody capable of detecting it in formalin-fixed, paraffin-embedded gastric tissue sections. Histochem Cell Biol ,148:463-471 2017 Author:Kawakubo M, Horiuchi K, Komura H, Sato Y, Kato M, Ikeyama M, Fukushima M, Yamada S, Ishizone S, Matsumoto T, Ota H, Sagara J, Nakayama J
Gastric gland mucin-specific O-glycan expression decreases with tumor progression from precursor lesions to pancreatic cancer. Cancer Sci ,108:1897-1902 2017 Author:Ohya A, Yamanoi K, Shimojo H, Fujii C, Nakayama J
Gastric hepatoid adenocarcinoma resulting in a spontaneous gastric perforation: a case report and review of the literature. BMC Cancer ,17:368 2017 Author:Yoshizawa J, Ishizone S, Ikeyama M, Nakayama J
Adenocarcinoma of Barrett’s esophagus in a dog. J Toxicol Pathol ,30:239-243 2017 Author:Chambers JK, Saito T, Fukushima K, Kakuta S, Nakayama J, Ohno K, Tsujimoto H, Nakayama H, Uchida K
Potential involvement of chondroitin sulfate A in the pathogenesis of ameloblastoma. Acta Histochem,119:439-445 2017 Author:Li X, Kurita H, Xiao T, Iijima K, Kurashina K, Nakayama J
High expression of ADAM10 predicts a poor prognosis for patients with glioblastoma Int J Clin Exp Pathol,10(1):618-624 2017 Author:Kanaya K, Sakai K, Hongo K, Fukushima M, Kawakubo M, Nakayama J
The ROS-generating oxidase Nox1 is required for epithelial restitution following colitis Exp Anim ,65:197-205 2016 Author:Kato M, Marumo M, Nakayama J, Matsumoto M, Yabe-Nishimura C, Kamata T
Enhanced expression of fibroblast growth factor receptor 3 IIIc promotes human esophageal carcinoma cell proliferation J Histochem Cytochem,64(1):7-17 2016 Author:Ueno N, Shimizu A, Kanai M, Iwaya Y, Nakayama J, Seo MK
Chondroitin sulfate synthase 1 expression is associated with malignant potential of soft tissue sarcomas with myxoid substance Hum Pathol ,50:15-23 2016 Author:Momose T, Yoshimura Y, Harumiya S, Isobe K, Kito M, Fukushima M, Kato H, Nakayama J
Axonal TDP-43 aggregates in sporadic amyotrophic lateral sclerosis. Neuropathol Appl Neurobiol,42(6):561-572 2016 Author:Onozato T, Nakahara A, Suzuki-Kouyama E, Hineno A, Yasude T, Nakamura T, Yahikozawa H, Watanabe M, Kayanuma K, Makishita H, Ohara S, Hashimoto T, Higuchi K, Sakai T, Asano K, Hashimoto T, Kanno H, Nakayama J, Oyanagi K
Up-regulated epidermal growth factor receptor expression following near-infrared irradiation simulating solar radiation in a 3-dimensional reconstructed human corneal epithelial tissue culture model Clin Interv Aging,11:1027-1033 2016 Author:Tanaka Y, Nakayama J
Unexpected occurrence of fetal hemophagocytic syndrome in a patient with hereditary diffuse leukoencephalopathy with spheroids Case Rep Clin Med,5:77-84 2016 Author:Kondo Y, Kinoshita M, Yoshida T, Matoba H, Uehara T, Ikeyama M, Nakayama J, Yoshida K, Ikeda S-i
Nox4-generated ROS Regulate TGF-β1-induced Motility of Colon Cancer Cells through the Low Molecular Weight Protein Tyrosine Phosphatase-Rho Signaling Pathway 信州医学雑誌,63(5):281-293 2015(Oct. 10) Author:Zhang Y, Nakayama J, Kamata T
Decreased expression of gastric gland mucin-specific glycan α1,4-linked N-acetylglucosamine on its scaffold mucin 6 is associated with malignant potential of pyloric gland adenoma of the stomach Histopathology ,67(6):898-904 2015 Author:Yamanoi K, Sekine S, Higuchi K, Kushima R, Nakayama J
Malignant meningioma with adenocarcinoma-like metaplasia: Demonstration of intestinal phenotype Neuropathology ,35(2):158-164 2015 Author:Takayama Y, Nobusawa S, Ochiai I, Watanabe H, Ishigame H, Ikota H, Hirato J, Nakayama J, Yokoo H
Reduced gland mucin-specific O-glycan in gastric atrophy: A possible risk factor for differentiated-type adenocarcinoma of the stomach J Gastroenterol Hepatol ,30(10):1478-1484 2015 Author:Yamada S, Okamura T, Kobayashi S, Tanaka E, Nakayama J
Breast metastases of gastric signet-ring cell carcinoma: a report of two cases and review of the literature OncoTargets Ther,8:91-97 2015 Author:Iesato A, Oba T, Ono M, Hanamura T, Watanabe T, Ito T, Kanai T, Maeno K, Ishizaka K, Kitabatake H, Takeuchi D, Suzuki A, Nakayama J, Ito K
Synthetic di-sulfated iduronic acid attenuates asthmatic response by blocking T-cell recruitment to inflammatory sites Proc Natl Acad Sci USA,111(22):8173-8178 2014 Author:Nonaka M, Bao X, Matsumura F, Götze S, Kandasamy J, Kononov A, Broide DH, Nakayama J, Seeberger PH, Fukuda M
Loss of gastric gland mucin-specific O-glycan is significantly associated with progression of differentiated-type adenocarcinoma of the stomach Cancer Sci,105:126-133 2014 Author:Shiratsu K, Higuchi K, Nakayama J
Reduced expression of αGlcNAc in Barrett’s esophagus adjacent to Barrett’s adenocarcinoma - Possible biomarker to predict the malignant potential of Barrett’s esophagus – Histopathology,64:536-546 2014 Author:Iwaya Y, Hasebe O, Koide N, Kitahara K, Suga T, Shinji A, Muraki T, Yokosawa S, Yamada S, Arakura N, Tanaka E, Nakayama J
Dual roles of gastric gland mucin-specific O-glycans in prevention of gastric cancer Acta Histochem Cytochem,47(1):1-9 2014 Author:Nakayama J
Defect of suppression of inflammasome-independent interleukin-8 secretion from SW982 synovial sarcoma cells by familial Mediterranean fever-derived pyrin mutations Mol Biol Rep,41:545-553 2014 Author:Sugiyama R, Agematsu K, Migita K, Nakayama J, Mokuda S, Ogura F, Haraikawa K, Okumura C, Suehiro S, Morikawa S, Ito Y, Masumoto J
Gliomatosis encephali” as a novel category of brain tumors by the first autopsy case report of gliomatosis cerebelli Neuropathology,34(3):295-303 2014 Author:Nakahara A, Yoshida T, Yazawa M, Ehara T, Nakayama J, Kakita A, Ogura R, Asakawa M, Suzuki-Kouyama E, Oyanagi K
Overexpression of O-GlcNAc by prostate cancer cells is significantly associated with poor prognosis of patients Prostate Cancer Prost Dis,17:18-22 2014 Author:Kamigaito T, Okaneya T, Shimojo H, Nishizawa O, Nakayama J
Development of pro-apoptotic peptides as potential therapy for peritoneal endometriosis Nat Commun,5:4478 2014 Author:Sugihara K, Kobayashi Y, Suzuki A, Tamura N, Motamedchaboki K, Huang C-T, Akama T, Pecotte J, Frost P, Bauer C, Jimenez J, Nakayama J, Aoki D, Fukuda MN
In vivo regulation of steroid hormones by the chst10 sulfotransferase in mouse J Biol Chem,288:5007-5016 2013 Author:Suzuki-Anekoji M, Suzuki A, Wu S-W, Angata K, Murai K, Sugihara K, Akama TO, Khoo K-H, Nakayama J, Fukuda MN, Fukuda M
Immunohistochemical expression of core2 β1-6 N-acetylglucosaminyl transferase 1 (C2GnT1) in endometrioid type of endometrial carcinoma: a novel potential prognostic factor Histopathology,62(7):986-993 2013 Author:Miyamoto T, Suzuki A, Asaka R, Ishikawa, Yamada Y, Kobara H, Nakayama J, Shiozawa T
Primary malignant sarcomatoid mesothelioma in the pericardium Intern Med,52(2):249-253 2013 Author:Tateishi K, Ikeda M, Yokoyama T, Urushihata K, Yamamoto H, Hanaoka M, Kubo K, Sakai Y, Nakayama J, Koizumi T
Lymphocyte recruitment via high endothelial venules in lymphoid stroma of Warthin's tumour Pathology,45(2):150-154 2013 Author:Ohya A, Kobayashi M, Sakai Y, Kawashima H, Kageyama S, Nakayama J
Periductal induction of high endothelial venule-like vessels in type 1 autoimmune pancreatitis Pancreas,42(1):53-59 2013 Author:Maruyama M, Kobayashi M, Sakai Y, Hiraoka N, Oya A, Kageyama S, Tanaka E, Nakayama J, Morohoshi T
High levels of FOXP3+ regulatory T cells in gastric MALT lymphoma predicts responsiveness to Helicobacter pylori eradication Helicobacter,18(5):356-362 2013 Author:Iwaya Y, Kobayashi M, Momose M, Hiraoka N, Sakai Y, Akamatsu T, Tanaka E, Ohtani H, Fukuda M, Nakayama J
Helicobacter pylori cholesteryl α-glucosides contribute to its pathogenicity and immune response by natural killer T cells PLoS One,8(12):e78191 2013 Author:Ito Y, Vela JL, Matsumura F, Hoshino H, Tyznik A, Lee H, Girardi E, Zajonc DM, Liddington, Kobayashi M, Bao X, Bugaytsova J, Borén T, Jin R, Zong Y, Seeberger PH, Nakayama J, Kronenberg M, Fukuda M
Crucial role of hyaluronan in neointimal formation after vascular injury PLoS One,8(3):e58760 2013 Author:Kashima Y, Takahashi M, Shiba Y, Itano N, Izawa A, Koyama J, Nakayama J, Taniguchi S, Kimata K, Ikeda U
Role of GalNAc4S-6ST in astrocytic tumor progression PLoS One,8:e54278 2013 Author:Kobayashi T, Yan H, Kurahashi Y, Ito Y, Maeda H, Tada T, Hongo K, Nakayama J
Essential role of gastric gland mucin in preventing gastric cancer in mice J Clin Invest,122(3):923-934 2012 Author:Karasawa F, Shiota A, Goso Y, Kobayashi M, Sato Y, Masumoto J, Fujiwara M, Yokosawa S, Muraki T, Miyagawa S, Ueda M, Fukuda MN, Fukuda M, Ishihara K, Nakayama J
Non-thermal DNA damage of cancer cells using near-infrared irradiation Cancer Sci,103(8):1467-1473 2012 Author:Tanaka Y, Tatewaki N, Nishida H, Eitsuka T, Ikekawa N, Nakayama J
Expression of long-form N-acetylglucosamine-6-O-sulfotransferase 1 in human high endothelial venules J Histochem Cytochem,60(5):397-407 2012 Author:Fujiwara M, Kobayashi M, Hoshino H, Uchimura K, Nakada T, Masumoto J, Sakai Y, Fukuda M, Nakayama J
Two distinct lymphocyte homing systems involved in the pathogenesis of chronic inflammatory gastrointestinal diseases Semin Immunopathol,34:401-413 2012 Author:Kobayashi M, Hoshino H, Suzawa K, Sakai Y, Nakayama J, Fukuda M
Glycoside hydrolase family 89 α-N-acetylglucosaminidase from Clostridium perfringens specifically acts on GlcNAcα 1,4Galβ1R at the non-reducing terminus of O-glycans in gastric mucin J Biol Chem,286(8):6479-6489 2011 Author:Fujita M, Tsuchida A, Hirata A, Kobayashi N, Goto K, Osumi K, Hirose Y, Nakayama J, Yamanoi T, Ashida H, Mizuno K
HNK-1 glycan functions as a tumor suppressor for astrocytic tumor J Biol Chem,286(37):32824-32833 2011 Author:Suzuki M, Suzuki M, Kobayashi T, Sato Y, Nakayama J, Suzuki A, Bao X, Angata K, Fukuda M
O-Glycans carrying non-sulfated sialyl Lewis X appearing on HEV-like vessels in gastric MALT lymphoma function as L-selectin ligands J Pathol,224:67-77 2011 Author:Kobayashi M, MitomaJ, Hoshino H, Yu SY, Shimojo Y, Suzawa K, Khoo KH, Fukuda M, Nakayama J
Inflammasome activation of cardiac fibroblasts is effential for myocardial ischemia/reperfusion injury Circulation,123:594-604 2011 Author:Kawaguchi M, Takahashi M, Hata T, Kashima Y, Usui F, Morimoto H, Izawa A, Takahashi Y, Masumoto J, Koyama J, Hongo M, Noda T, Nakayama J, Sagara J, Taniguchi S, Ikeda U
Targeted drug delivery to tumor vasculature by a carbohydrate mimetic peptide Proc Natl Acad Sci USA,108(49):19587–19592 2011 Author:Hatakeyama S, Sugihara K, Shibata TK, Nakayama J, Akama TO, Tamura N, Wong S, Bobkov AA, Takano Y, Ohyama C, Fukuda M, Fukuda MN
Reduced glycosylation of α-dystroglycans on carcinoma cells contributes to formation of highly infiltrative histological patterns in prostate cancer Prostate,71:1151-1157 2011 Author:Shimojo H, Kobayashi M, Kamigaito T, Shimojo Y, Fukuda M, Nakayama J
Membrane-associated activation of cholesterol α-glucosyltransferase, an enzyme responsible for biosynthesis of cholesteryl-α-D-glucopyranoside in Helicobacter pylori critical for its survival J Histochem Cytochem,59(1):98-105 2011 Author:Hoshino H, Tsuchida A, Kametani K, Mori M, Nishizawa T, Suzuki T, Nakamura H, Lee H, Ito Y, Kobayashi M, Masumoto J, Fujita M, Fukuda M, Nakayama J
An integrin α4β7•IgG heterodimeric chimera binds to MAdCAM-1 on high endothelial venules in gut-associated lymphoid tissue J Histochem Cytochem,59:572-583 2011 Author:Hoshino H, Kobayashi M, Mitoma J, Sato Y, Fukuda M, Nakayama J
A rare lung nodule consisting of adenocarcinoma and amyloid deposition in a patient with primary systemic AL amyloidosis Inter Med,50:243-246 2011 Author:Miyazaki D, Yazaki M, Ishii W, Matsuda M, Hoshii Y, Nara K, Nakayama J, Ikeda S
Gliosarcoma arising from a fibrillary astrocytoma J Clin Neurosci,18(9):1251-1254 2011 Author:Kobayashi T, Sakai K, Tada T, Sekiguchi Y, Hara Y, Kodama K, Goto T, Tanaka Y, Sano K, Nakayama J, Hongo K
COP35, a cholangiocarcinoma-binding oligo-peptide, interacts with the clathrin heavy chain accompanied by GRP78 Mol Cancer Res,9(6):688-701 2011 Author:Kitahara H, Masumoto J, Parker AL, Maruta F, Kubo N, Shimizu A, Akita N, Miwa S, Kobayashi N, Nakayama J, Miyagawa S
Core2 O-glycan structure functions in gastrointestinal cell differentiation by regulating cell surface expression of sucrase isomaltase and dipeptidyl peptidase-IV J Biol Chem,285(48):37683-37692 2010 Author:Lee SH, Yu SY, Nakayama J, Khoo KH, Stone EL, Fukuda M, Marth JD, Fukuda M
Non-thermal cytocidal effect of infrared irradiation on cultured cancer cells using specialized device Cancer Sci,101(6):1396-1402 2010 Author:Tanaka, Yohei; Matsuo, Kiyoshi;Yuzuriha, Shunsuke; Yan, Huimin; Nakayama, Jun
Reversion-inducing cysteine-rich protein with kazal motifs and matrix metalloproteinase-9 are prognostic markers in skull base chordomas NEUROSURGICAL REVIEW,33(2):167-173 2010 Author:Rahmah, Nunung Nur; Sakai, Keiichi; Nakayama, Jun; Hongo, Kazuhiro
Nasu-Hakola disease: The first case reported by Nasu and review Neuropathology,30(5):463-470 2010 Author:Kaneko M, Sano K, Nakayama J, Amano N
Identification of mRNA splicing factor as the endothelial receptor for carbohydrate-dependent lung colonization of cancer cells Proc Natl Acad Sci USA,106(9):3095-3100 2009 Author:Hatakeyama S, Sugihara K, Nakayama J, Akama TO, Wong SA, Kawashima H, Zhang J, Smith DF, Ohyama C, Fukuda M, Fukuda MN
Tumor suppressor function of laminin-binding alpha-dystroglycan requires a distinct beta3-N-acetylglucosaminyltransferase Proc Natl Acad Sci USA,106:12109-12114 2009 Author:Bao X, Kobayashi M, Hatakeyama S, Angata K, Gullberg D, Nakayama J, Fukuda MN, Fukuda M
Therapeutic and preventive effects of methotrexate on zymosan-induced arthritis in SKG mice J Vet Med Sci,71:713-717 2009 Author:Nagate T, Kawai J, Nakayama J
Role of sulfated O-glycans expressed by high endothelial venule-like vessels in pathogenesis of chronic inflammatory gastrointestinaldiseases BIOLOGICAL & PHARMACEUTICAL BULLETIN,32(5):774-779 2009 Author:Kobayashi, Motohiro; Fukuda, Minoru; Nakayama, Jun
Antigen p57/Kip2 as a potential negative regulator of human astrocytoma growth JOURNAL OF CLINICAL NEUROSCIENCE,16(12):1615-1618 2009 Author:Akaishi, Kotaro; Nakayama, Jun; Sakai, Keiichi; Kobayashi, Tatsuya; Rutka, James T.
Trophinin: what embryo implantation teaches us about human cancer Cancer Biol Ther,7:1165-1170 2008 Author:Fukuda MN, Sugihara K, Nakayama J
Immunohistochemical demonstration of proliferating lymphatic vessels in colorectal carcinoma and its clinicopathological significance Cancer Lett,246(42737):167-172 2007 Author:Omachi T, Kawai Y, Mizuno R, Nomiyama T, Miyagawa S, Ohhashi T, Nakayama J
The role of trophinin, an adhesion molecule unique to human trophoblasts, in progression of colorectal cancer Int J Cancer,121(5):1072-1078 2007 Author:Harada O, Suga T, Suzuki T, Nakamoto K, Kobayashi M, Nomiyama T, Nadano D, Ohyama C, Fukuda MN, Nakayama J
Preferential induction of peripheral lymph node addressin on high endothelial venule-like vessels in the active phase of ulcerative colitis Am J Gastroenterol,102:1499-1509 2007 Author:Suzawa K, Kobayashi M, Sakai Y, Hoshino H, Watanabe M, Harada O, Ohtani H, Fukuda M, Nakayama J
The utility of formalin-fixed and paraffin-embedded tissue blocks for quantitative analysis of N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase mRNA expressed by colorectal cancer cells Acta Histochem Cytochem,40(2):53-59 2007 Author:Ito Y, Watanabe M, Nishizawa T, Omachi T, Kobayashi T, Habuchi O, Nakayama J:
RNA interference-mediated knock-down of transient receptor potential vanilloid 1 prevents forepaw inflammatory hyperalgesia in rat Eur J Neurosci,25:2956-2963 2007 Author:Kasama S, Kawakubo M, Suzuki T, Nishizawa T, Ishida A, Nakayama J
Comparison of the histological and immunohistochemical features of the thymus in young- and elderly-onset myasthenia gravis without thymoma J Clin Neurosci,14(2):110-115 2007 Author:Ishii, W; Matsuda, M; Hanyuda, M; Momose, M; Nakayama, J; Ehara, T; Ikeda, S
Prognositic significance of the immunohistochemical staining of cleaved-caspase-3, an activated-form of caspase-3, in gliomas Clin Cancer Res,13(13):3868-3874 2007 Author:Kobayashi T, Masumoto J, Tada T, Nomiyama T, Hongo K, Nakayama J
Expression profiling of glycosyltransferases and related enzymes using in situ hybridization Methods Enzymol,416:120-129 2006 Author:Nakayama J, Suzuki M, Suzuki M, Fukuda M
Expression cloning of cholesterol alpha-glucosyltransferase, a unique enzyme that can be inhibited by natural antibiotic gastric mucin O-glycans, from Helicobacter pylori Biochem Biophys Res Commun,349(4):1235-1241 2006 Author:Lee, H; Kobayashi, M; Wang, P; Nakayama, J; Seeberger, PH; Fukuda, M
Lanosterol synthase mutations cause cholesterol deficiency-associated cataracts in the Shumiya cataract rat J Clin Invest,116(2):395-404 2006 Author:Mori, M; Li, GX; Abe, I; Nakayama, J; Guo, ZJ; Sawashita, J; Ugawa, T; Nishizono, S; Serikawa, T; Higuchi, K; Shumiya, S
Matrix morphogenesis in cornea is mediated by the modification of keratan sulfate by GlcNAc 6-O-sulfotransferase Proc Natl Acad Sci USA,103(36):13333-13338 2006 Author:Hayashida, Y; Akama, TO; Beecher, N; Lewis, P; Young, RD;Meek, KM; Kerr, B; Hughes, CE; Caterson, B; Tanigami, A; Nakayama, J; Fukada, MN; Tano, Y; Nishida, K; Quantock, AJ
Essential and mutually compensatory roles of alpha-mannosidase II and alpha-mannosidase IIx in N-glycan processing in vivo in mice Proc Natl Acad Sci USA,103(24):8983-8988 2006 Author:Akama, TO; Nakagawa, H; Wong, NK; Sutton-Smith, M; Dell, A; Morris, HR; Nakayama, J; Nishimura, SI; Pai, A; Moremen, KW; Marth, JD; Fukuda, MN
Identification of oligopeptides binding to peritoneal tumors of gastric cancer Cancer Sci,97(10):1075-1081 2006 Author:Akita, N; Maruta, F; Seymour, LW; Kerr, DJ; Parker, AL; Asai, T; Oku, N; Nakayama, J; Miyagawa, S
Clinical utility of quantitative RT-PCR targeted to alpha 1,4-N-acetylglucosaminyltransferase mRNA for detection of pancreatic cancer Cancer Sci,97(2):119-126 2006 Author:Ishizone, S; Yamauchi, K; Kawa, S; Suzuki, T; Shimizu, F; Harada, O; Sugiyama, A; Miyagawa, S; Fukuda, M; Nakayama, J
Hypermethylation of ASC/TMS1 is a sputum marker for late-stage lung cancer Cancer Res,66(12):6210-6218 2006 Author:Machida, EO; Brock, MV; Hooker, CM; Nakayama, J; Ishida, A; Amano, J; Picchi, MA; Belinsky, SA; Herman, JG; Taniguchi, S; Baylin, SB
Female adnexal tumor of probable wolffian origin: Morphological, immunohistochemical, and ultrastructural study with c-kit gene analysis Pathol Int,56(2):95-100 2006 Author:Harada, O; Ota, H; Takagi, K; Matsuura, H; Hidaka, E; Nakayama, J
Terminal alpha 1,4-linked N-acetylglucosamine in Helicobacter pylori-associated intestinal metaplasia of the human stomach and gastric carcinoma cell lines J Histochem Cytochem,54(5):585-591 2006 Author:Ferreira, B; Marcos, NT; David, L; Nakayama, J; Reis, CA
Efficacy of S-1 for patients with peritoneal metastasis of gastric cancer Chemotherapy,52(6):301-307 2006 Author:Ishizone, S; Maruta, F; Saito, H; Koide, N; Sugiyama, A; Nakayama, J; Miyagawa, S
Inhibition of NADPH oxidase 4 activates apoptosis via the AKT/apoptosis signal-regulating kinase 1 pathway in pancreatic cancer PANC-1 cells Oncogene,25(26):3699-3707 2006 Author:Mochizuki, T; Furuta, S; Mitsushita, J; Shang, W; Ito, M; Yokoo, Y; Yamaura, M; Ishizone, S; Nakayama, J; Konagai, A; Hirose, K; Kiyosawa,K; Kamata, T
Efficacy of mycophenolic acid combined with KRP-203, a novel immunomodulator, in a rat heart transplantation model J Heart Lung Transpl,25(3):302-309 2006 Author:Suzuki, C; Takahashi, M; Morimoto, H; Izawa, A; Ise, H; Fujishiro, J; Murakami, T; Ishiyama, J; Nakada, A; Nakayama, J; Shimada, K; Ikeda, U; Kobayashi, E
Expression of Fas ligand by hepatic macrophages in patients with fulminant hepatic failure Am J Gastroenterol,100(11):2551-2559 2005 Author:Mita A, Hashikura Y, Tagawa Y-i, Nakayama J, Kawakubo M, Miyagawa S
Malignant myoepithelioma (myoepithelial carcinoma) of soft tissue Pathol Int,55(8):510-513 2005 Author:Harada O, Ota H, Nakayama J
Arachidonic acid-induced COX-1 and COX-2-mediated vasodilation in rat gingival arterioles in vivo Jpn J Physiol,55(5):293-302 2005 Author:Nakatsuka A, Mizuno R, Ono N, Nakayama J, Ohhashi T
Crucial roles of mesodermal cell lineages in a murine embryonic stem cell-derived in vitro liver organogenesis system Stem Cells,23(7):903-913 2005 Author:Ogawa S, Tagawa Y, Kamiyoshi A, SuzukiA, Nakayama J, Hashikura Y, Miyagawa S
MCI-186 (edaravone), a free radical scavenger, attenuates hepatic warm ischemia-reperfusion injury in rats Transpl Int,18(7):844-853 2005 Author:Suzuki F, Hashikura Y, Ise H, Ishida A, Nakayama J, Takahashi M,Miyagawa S, Ikeda U
Expression of core 2 beta 1,6-N-acetylglucosaminyltransferase facilitates prostate cancer progression Glycobiology,15(10):1016-1024 2005 Author:Hagisawa S, Ohyama C, Takahashi T, Endoh M, Moriya T, Nakayama J, Arai Y, Fukuda M
Polysialic acid facilitates tumor invasion by glioma cells Glycobiology,15(9):887-894 2005 Author:Suzuki M, Suzuki M, Nakayama J, Suzuki A, Angata K, Chen S, Sakai K, Hagihara K, Yamaguchi Y, Fukuda M
N-acetylglucosamine-6-O-sulfotransferases 1 and 2 cooperatively control lymphocyte homing through L-selectin ligand biosynthesis in high endothelial venules Nat Immunol,6(11):1096-1104 2005 Author:Kawashima H, Petryniak B, Hiraoka N, Mitoma J, Huckaby V, Nakayama J, Uchimura K, Kadomatsu K, Muramatsu T, Lowe JB, Fukuda M
Molecular cloning and expression of HRLRRP, a novel heart-restricted leucine-rich repeat protein Biochem Biophys Res Commun,314(4):1086-1092 2004 Author:Nakane T, Satoh T, Inada Y, Nakayama J, Itoh E Chiba S
Natural antibiotic function of a human gastric mucin against Helicobacter pylori infection Science,305(5686):1003-1006 2004 Author:Kawakubo M, Ito Y, Okimura Y, Kobayashi M, Sakura K, Kasama S, Fukuda MN, Fukuda M, Katsuyama T, Nakayama J
Core 2 branching β1,6-N-acetylglucosaminyltransferase and heig endothelial venule-restricted sulfotransferase collaboratively control lymphocyte homing J Biol Chem,279(4):3058-3067 2004 Author:Hiraoka N, Kawashima H, Petryniak B, Nakayama J, Mitoma J, Marth JD, Lowe JB, Fukuda M
Induction of peripheral lymph node addressin in human gastric mucosa infected by Helicobacter pylori Proc Natl Acad Sci USA,101(51):17807-17812 2004 Author:Kobayashi M, Mitoma J, Nakamura N, Katsuyama T, Nakayama J, Fukuda M
Inducible expression of p57KIP2 inhibits glioma cell motility and invasion J Neurooncol,68(3):217-223 2004 Author:Sakai K, Peraud A, Mainprize T,Nakayama J, Tsugu A, Hongo K, Kobayashi S, Rutka JT T, Rutka
Functional correlation of trophinin expression with the malignancy of testicular germ cell tumor Cancer Res,64(12):4257-4262 2004 Author:Hatakeyama S, Ohyama C, Minagawa S, Inoue T, Kakinuma H, Kyan A, Arai Y, Suga T, Nakayama J, Kato T, Habuchi T, Fukuda MN
Symmetric Dumbbell Ganglioneuromas of Bilateral C2 and C3 Roots with Intradural Extension Associated with Von Recklinghausen's Disease:Case Report Surg Neurol,61(5):468-473 2004 Author:Kyoshima K, Sakai K, Kanaji M, Oikawa S, Kobayashi S, Sato A, Nakayama J
Pulmonary lymphoepithelioma-like carcinoma: predominant infiltration of tumor-associated cytotoxic Tlymphocytes might represent the enhanced tumor immunity Intern Med,43(4):323-326 2004 Author:Kobayashi M, Ito M, Sano K, Honda T, Nakayama J
Degenerative thalamic hamartoma: CT and MR imaging features Am J Neuroradiol,25(5):766-768 2004 Author:Kaneko T, Kawakami R, Fujinaga Y, Oguchi K, Nakayama J, Hongo K, Kadoya M
Polysialic acid and HNK-1 are expressed in the adult rat vestibular endorgans Neuroreport,15(10):1575-1578 2004 Author:Isawa M, Takumi Y, Hashimoto S, Nakayama J, Usami S
A subtype of human gastric mucins expressing alpha1,4-GlcNAc-capped O-glycans functions as a natural antibiotic against Helicobacter pylori infection GLYCOBIOLOGY,14(11):1073-1073 2004 Author:Nakayama, J; Kawakubo, M; Ito, Y; Kobayashi, M; Fukuda, MN; Fukuda, M; Katsuyama, T
Gross total surgical removal of malignant glioma from the medulla oblongata: report of two adult cases with reference to surgicalanatomy J Clin Neurosci,11(1):75-80 2004 Author:Kyoshima K, Sakai K, Goto T, Tanabe A, Sato A, Nagashima H, Nakayama J
Polysialic acid and mucin type O-glycans on the neural cell adhesion molecule differentially regulate myoblast fusion J Biol Chem,278(49):49459-49468 2003 Author:Suzuki, M; Angata, K; Nakayama, J; Fukuda, M
Implantation-dependent expression of trophinin by maternal Fallopian tube epithelia during tubal pregnancies: Possible role of human chorionic gonadotrophin on ectopic pregnancy Am J Pathol,163(6):2211-2219 2003 Author:Nakayama J, Aoki D, Suga T, Akama T O, Ishizone S, Yamaguchi H, Imakawa K, Nadano D, Fazleabas A T, Katsuyama T, Nozawa S, Fukuda M N
Usefulness of the real-time reverse transcription-polymerase chain reaction assay targeted to alpha1,4-N-acetylglucosaminyltransferase for the detection of gastric cancer Lab Invest,83(2):187-197 2003 Author:Shimizu F, Nakayama J, Ishizone S, Zhang M X, Kawakubo M, Ota H, Sugiyama A, Kawasaki S, Fukuda M, Katsuyama T
Life-threatening veno-occlusive disease after living-related liver transplantation Transplantation,75(5):727-730 2003 Author:Nakazawa, Y; Chisuwa, H; Mita, A; Ikegami,T; Hashikura, Y; Terada, M; Nakayama, J; Kawasaki, S
Expression of gastric gland mucous cell-type mucin in normal and neoplastic human tissues J Histochem Cytochem,51(12):1689-1698 2003 Author:Nakajima, K; Ota, H; Zhang, MX; Sano, K; Honda, T; Ishii, K; Nakayama, J
Immunohistochemical localization of hepatocyte growth factor activator (HGFA) in developing mouse liver tissues: Heterogeneous distribution of HGFA protein J Histochem Cytochem,51(9):1139-1149 2003 Author:Iida, I; Johkura, K; Teng, RF; Kubota, S; Cui, L; Zhao, X; Ogiwara, N; Okouchi, Y; Asanuma, K; Nakayama, J; Sasaki, K
Differential expression of ribosomal proteins in human normal and neoplastic colorectum J Histochem Cytochem,51(5):567-573 2003 Author:Kasai, H; Nadano, D; Hidaka, E; Higuchi, K; Kawakubo, M; Sato, TA; Nakayama, J
Purification and measurement of HDL3-binding proteins in human peripheral blood mononuclear cells Ann Clin Lab Sci,33(3):271-278 2003 Author:Hidaka, H; Tozuka, M; Yamauchi, K; Ohta, H; Nakayama, J; Katsuyama, T
Temporal and spatial expression profiles of BMP receptors and Noggin during BMP-2-induced ectopic bone formation J Bone Miner Res,18(10):1854-1862 2003 Author:Nakamura, Y; Wakitani, S; Nakayama, J; Wakabayashi, S; Horiuchi, H; Takaoka, K
Mouse model of N-acetylgalactosamine-6-sulfate sulfatase deficiency (Galns(-/-)) produced by targeted disruption of the gene defective in Morquio A disease Hum Mol Genet,12(24):3349-3358 2003 Author:Tomatsu, S; Orii, KO; Vogler, C; Nakayama,J; Levy, B; Grubb, JH; Gutierrez, MA; Shim, S; Yamaguchi, S; Nishioka, T; Montano, AM; Noguchi, A; Orii, T; Kondo, N; Sly, WS
Helicobacter pylori infection up-regulates gland mucous cell-type mucins in gastric pyloric mucosa Helicobacter,8(6):594-600 2003 Author:Matsuzawa M, Ota H, Hiyama M, Zhang MX, Sano K, Honda T, Ueno I, Akamatsu T, Nakayama J
a1,4-N-acetylglucosaminyltransferase and gastric cancer. Barrett JC, Imai K, Kakizoe T, Shively J E, and Yamaguchi K eds: Basic and Clinical Research on Tumor Markers Extended Abstracts for the 32nd International Symposium of the Princess Takamatsu Cancer Research Fund,:61-65 2002 Author:Nakayama J, Shimizu F, Zhang MX, Fukuda M, Katsuyama T
a4-N-acetylglucosaminyltra- nsferase Taniguchi N, Honke K, Fukuda M eds: Handbook of Glycosyltransferases and Related Genes,:151-157 2002 Author:Nakayama J
Human tastin, a proline-rich cytoplasmic protein, associates with the microtubular cytoskeleton Biochem J,364:669-677 2002 Author:Nadano D, Nakayama J, Matsuzawa S, Sato T, Matsuda T, Fukuda MN
Significant differences between mouse and human trophinins are revealed by their expression patterns and targeted disruption of mouse trophinin gene Biol Reprod,66(2):313-321 2002 Author:Nadano D, Sugihara K, Paria BC, Saburi S, Copeland NG, Gilbert DJ, Jenkins NA, Nakayama J, Fukuda MN
Sialyl Lewis X-dependent lung colonization of B16 melanoma cells through a selectin-like endothelial receptor distinct from E- or P-selectin Cancer Res,62(15):4194-4198 2002 Author:Zhang J, Nakayama J, Ohyama C, Suzuki M, Suzuki A, Fukuda M, Fukuda M N
Association of GM4 ganglioside with the membrane surrounding lipid droplets in shark liver J Lipid Res,43(7):1019-1025 2002 Author:Li Y-T, Sugiyama E, Ariga T, Nakayama J, Hayama M, Hama Y, Nakagawa H, Tai T, Maskos K, Li S-C, Kasama T
Anti-neovascular therapy using novel peptides homing to angiogenic vessels Oncogene,21(17):2662-2669 2002 Author:Oku N, Asai T, Watanabe K, Kuromi K, Nagatsuka M, Kurohane K, Kikkawa H, Ogino K, Tanaka M, Ishikawa D, Tsukada H, Momose M, Nakayama J, Taki T
Evaluation of 5-S-cysteinyidopa as a markerof melanoma progression: 10 years' experience MELANOMA RESEARCH,12(3):245-253 2002 Author:Wakamatsu, K; Kageshita, T; Furue, M; Hatta, N; Kiyohara, Y; Nakayama, J; Ono, T; Saida, T; Takata, M; Tsuchida, T; Uhara, H; Yamamoto, A; Yamazaki, N; Naito, A; Ito, S
Malignant astrocytoma of the conus medullaris treated by spinal cordectomy J Clin Neurosci,9(2):211-216 2002 Author:Kyoshima K,Ito K, Tanabe A, Iwashita T, Goto T, Sato A, Nakayama J
Usefulness of albumin scintigraphyin a pediatric liver transplant recipient with gastrointestinal posttransplant lymphoproliferative disorder Liver Transpl,8:568-569 2002 Author:Mita A, Hashikura Y, Momose M, Nakayama J, Sasaki E, Ikegami T, Nakazawa Y, Chisuwa H, Terada M, Kawasaki S
A novel endo-beta-galactosidase from Clostridium perfringens that liberates the disaccharide GlcNAc alpha 1,4Gal from glycans specifically expressed in the gastric gland mucous cell-type mucin J Biol Chem,276(30):28226-28232 2001 Author:Ashida H, Anderson K, Nakayama J, Maskos K, Chou C-W, Cole R B, Li S-C, Li Y-T
Human corneal GlcNAc 6-O-sulfotransferase and mouse intestinal GlcNAc 6-O-sulfotransferase both produce keratan sulfate J Biol Chem,276(19):16271-16278 2001 Author:Akama, TO; Nakayama, J; Nishida, K; Hiraoka, N; Suzuki, M; McAuliffe, J; Hindsgaul, O; Fukuda, M; Fukuda, MN
Molecular cloning and characterization of a human beta-Gal-3'-sulfotransferase that acts on both type 1 and type 2 (Galbeta1-3/1-4GlcNAc-R) oligosaccharides J Biol Chem,276(1):267-274 2001 Author:Honke K, Tsuda M, KoyotaS, Wada Y, Iida-Tanaka N, Ishizuka I, Nakayama J, Taniguchi N
Cell lineage specificity of newly raised monoclonal antibodies against gastric mucins in normal, metaplastic, and neoplastic humantissues and their application to pathology diagnosis Am J Clin Pathol,115(1):69-79 2001 Author:Ota, H; Hayama, M; Nakayama, J; Hidaka, H; Honda, T; Ishii, K; Fukushima, M; Uehara, T; Kurihara, M; Ishihara, K; Hotta, K; Katsuyama, T
Novel sulfated lymphocyte homing receptors and their control by a core1 extension beta1,3-N-acetylglucosaminyltransferase Cell,105(7):957-969 2001 Author:Yeh J-C, Hiraoka N, Petryniak B, Nakayama J, Ellise L G, Rabuka D, Hindsgaul O, Marth J, Lowe J B, Fukuda M
Effect of polysialic acid on the tumor xenografts implanted into nude mice Int J Cancer,94(2):192-199 2001 Author:Jimbo, T; Nakayama, J; Akahane, K; Fukuda, M
Fatal hemophagocytic syndrome after living-related liver transplantation - A report of two cases Transplantation,72(11):1843-1846 2001 Author:Chisuwa, H; Hashikura, Y; Nakazawa, Y; Kamijo, T; Nakazawa, K; Nakayama, J; Oh-ishi, T; Ikegami, T; Terada, M; Kawasaki, S
Clinicopathological significance of core 2 beta1,6-N-acetylglucosaminyltransferase messenger RNA expressed in the pulmonary adenocarcinoma determined by in situ hybridization Cancer Res,61(5):2226-2231 2001 Author:Machida E, Nakayama J, Amano J, Fukuda M
Prognostic significance of polysialic acid expression in resected non-small cell lung cancer Cancer Res,61(4):1666-1670 2001 Author:Tanaka, F; Otake, Y; Nakagawa, T; Kawano, Y; Miyahara, R; Li, M; Yanagihara, K; Inui, K; Oyanagi, H; Yamada, T; Nakayama, J; Fujimoto, I; Ikenaka, K; Wada, H
Expression of apoptosis-associated speck-like protein containing a caspase recruitment domain, a pyrin N-terminal homology domain-containing protein, in normal human tissues J Histochem Cytochem,49(10):1269-1275 2001 Author:Masumoto, J; Taniguchi, S; Nakayama, J; Shiohara, M; Hidaka, E; Katsuyama, T; Murase, S; Sagara, J
Extrahepatic expression of apolipoprotein A-II in mouse tissues: Possible contribution to mouse senile amyloidosis J Histochem Cytochem,49(6):739-747 2001 Author:Fu, L; Matsuyama, I; Chiba, T; Xing, YM; Korenaga, T; Guo, ZJ; Fu, XY; Nakayama, J; Mori, M; Higuchi, K
Immunohistochemical demonstration od alpha,4-N-acetylglucosaminyltransferase that forms GlcNAc alpha 1,4Gal beta residues in human gastrointestinal mucosa J Histochem Cytochem,49(5):587-596 2001 Author:Zhang, MX; Nakayama, J; Hidaka, E; Kubota, S; Yan, J; Ota, H; Fukuda, M
Helicobacter pylori and two ultrastructurally distinct layers of gastric mucous cell mucins in the surfacemucous gel layer Gut,49(4):474-480 2001 Author:Hidaka, E; Ota, H; Hidaka, H; Hayama, M; Matsuzawa, K; Akamatsu, T; Nakayama, J; Katsuyama, T
Coexistence of gland mucous cell-type mucin and lysozyme in gastric gland mucous cells Histochem Cell Biol,113(2):91-98 2000 Author:Hidaka, E; Ota, H; Katsuyama, T; Nakayama, J; Momose, M; Hidaka, H; Ishii, K; Murata, F; Tsuyama, S; Kurihara, M; Ishihara, K; Hotta, K
Proliferation-associated expression of the MEN1 gene as revealed by in situ hybridization: Possible role of the menin as a negative regulator of cell proliferation under DNA damage Lab Invest,80(6):797-804 2000 Author:Ikeo, Y; Sakurai, A; Suzuki, R; Zhang, MX; Koizumi, S; Takeuchi, Y; Yumita, W; Nakayama, J; Hashizume, K
Primary cardiac malignant fibrous histiocytoma in the right ventricular infundibulum treated with a cavo-pulmonary shunt and coronary embolization Jpn Circ J,64(12):982-984 2000 Author:Owa, M; Higashikata, T; Shimada, H; Kitahara, H; Asano, M; Nakayama, J; Hikita, H; Koyama, J; Sakurai, S; Ikeda, S
Expression of polysialic acid and STX, a human polysialyltransferase, is correlated with tumor progression in non small cell lung cancer Cancer Res,60(11):3072-3080 2000 Author:Tanaka, F; Otake, Y;Nakagawa, T; Kawano, Y; Miyahara, R; Li, M; Yanagihara, K; Nakayama, J; Fujimoto, I; Ikenaka, K; Wada, H
Recent progress in paradoxical concanavalin A staining Acta Histochem Cytochem,33(3):153-157 2000 Author:Nakayama, J; Katsuyama, T; Fukuda, M
Macular corneal dystrophy type I and type II are caused by distinct mutations in a new sulphotransferase gene Nat Genet,26(2):237-241 2000 Author:Akama T O, Nishida K, Nakayama J, Watanabe H, Ozaki K, Nakamura T, Dota A, Kawasaki S, Inoue Y, Maeda N, Yamamoto S, Fujiwara T, Thonar E J-M A, Shimomura Y, Kinoshita S, Tanigami A, Fukuda M N
Expression cloning of a human alpha1,4-N-acetylglucosaminyltransferase that forms GlcNAc alpha1-4Galbeta-R, a glycan specifically expressed in the gastric gland mucous cell-type mucin Proc Natl Acad Sci USA,96(16):8991-8996 1999 Author:Nakayama J, Yeh J-C, Misra A K, Ito S, Katsuyama T, Fukuda M
Expression of trophinin, tastin, and bystin by trophoblast and endometrial cells in human placenta Biol Reprod,60(3):621-627 1999 Author:Suzuki, N; Nakayama, J; Shih, IM; Aoki, D; Nozawa, S; Fukuda, MN
Detection of GB virus-C hepatitis G virus genome in peripheral blood mononuclear cells and liver tissue J Med Virol,57(2):114-121 1999 Author:Kobayashi, M; Tanaka, E; Nakayama, J; Furuwatari, C; Katsuyama, T; Kawasaki, S; Kiyosawa, K
Brunner's gland metaplasia of residual jejunum developed long after wide resection of the small intestine Pathol Int,49(10):918-920 1999 Author:Nakamura, T; Shimada, M; Nakayama, J; Katsuyama, T
Expression of N-acetyllactosamine and beta 1,4-galactosyltransferase (beta 4GalT-I) during adenoma-carcinoma sequence in the human colorectum J Histochem Cytochem,47(12):1593-1601 1999 Author:Ichikawa, T; Nakayama, J; Sakura, N; Hashimoto, T; Fukuda, M; Fukuda,MN; Taki, T
The identification of specific high density lipoprotein(3) binding sites on human blood monocytes using fluorescence-labeled ligand J Lipid Res,40(6):1131-1139 1999 Author:Hidaka, H; Hidaka, E; Tozuka, M; Nakayama, J; Katsuyama, T; Fidge, N
A novel, high endothelial venule-specific sulfotransferase expresses 6-sulfo sialyl Lewis x, an L-selectin ligand displayed by CD34 Immunity,11(1):79-89 1999 Author:Hiraoka N, Petryniak B, Nakayama J, Tsuboi S, Suzuki M, Yeh J-C, Izawa D, Tanaka T, Miyasaka M, Lowe J B, Fukuda M
Helicobacter pylori infection produces reversible glycosylation changes to gastric mucins Virchows Archiv,433(5):419-426 1998 Author:Ota, H; Nakayama, J; Momose, M; Hayama, M; Akamatsu, T; Katsuyama, T; Graham, DY;Genta, RM
New monoclonal antibodies against gastric gland mucous cell-type mucins: a comparative immunohistochemical study Histochem Cell Biol,110(2):113-119 1998 Author:Ota, H; Nakayama, J; Momose, M; Kurihara, M; Ishihara, K; Hotta, K; Katsuyama, T
Polysialic acid, a unique glycan that is developmentally regulated by two polysialyltransferases, PST and STX, in the central nervous system: From biosynthesis to function Pathol Int,48(9):665-677 1998 Author:Nakayama, J; Angata, K; Ong, E; Katsuyama, T; Fukuda, M
Developmental regulation of polysialic acid synthesis in mouse directed by two polysialyltransferases,PST and STX Glycobiology,8(4):415-424 1998 Author:Ong, E; Nakayama, J; Angata, K; Reyes, L; Katsuyama, T; Arai, Y; Fukuda, M
Human STX polysialyltransferase forms the embryonic form of the neural cell adhesion molecule - Tissue-specific expression, neurite outgrowth, and chromosomal localization in comparison with another polysialyltransferase, PST J Biol Chem,272(11):7182-7190 1997 Author:Angata, K; Nakayama, J; Fredette, B; Chong, K; Ranscht, B; Fukuda, M
Expression cloning and characterization of a cDNA encoding a novel membrane protein required for the formation of O-acetylated ganglioside: A putative acetyl-CoA transporter Proc Natl Acad Sci USA,94:2897-2902 1997 Author:Kanamori A, Nakayama J, Fukuda MN, Stallcup W B, Sasaki K, Fukuda M, Hirabayashi Y
Carcinoma-associated expression of core 2 beta-1,6-N-acetylglucosaminyltransferase gene in human colorectal cancer: Role of O-glycans in tumor progression Cancer Res,57(23):5201-5206 1997 Author:Shimodaira, K; Nakayama, J; Nakamura, N; Hasebe, O; Katsuyama, T; Fukuda, M
Enhanced expression of prostate-specific membrane antigen gene in prostate cancer as revealed by in situ hybridization Cancer Res,57(12):2321-2324 1997 Author:Kawakami, M; Nakayama, J
Histone H3 messenger RNA in situhybridization for identifying proliferating cells in formalin-fixed rat gastric mucosa Histochem J,29(11-12):867-873 1997 Author:Maeyama, H; Furuwatari, C; Ota, H; Akamatsu, T; Nakayama, J; Katsuyama, T
Expression cloning of a human GT3 synthase. GD3 and GT3 are synthesized by a single enzyme J Biol Chem,271:3684-3691 1996 Author:Nakayama J, Fukuda MN, Hirabayashi Y, Kanamori A, Sasaki K, Nishi T, Fukuda M
A human polysialyltransferase directs in vitro synthesis of polysialic acid J Biol Chem,271:1829-1832 1996 Author:Nakayama J, Fukuda M
Expression cloning of glycosyltransferases Glycobiology,6:683-689 1996 Author:Fukuda M, Bierhuizen MFA, Nakayama J
Expression cloning of a human polysialyltransferase that forms the polysialylated neural cell adhesion molecule present in embryonic brain Proc Natl Acad Sci USA,92:7031-7035 1995 Author:Nakayama J, Fukuda MN, Fredette B, Ranscht B, Fukuda M
Application of mucin histochemistry for pathological diagnosis. - Expession of gastric phenoypes in metaplastic and neoplastic lesions and its relation to the organoid differentiation - Acta Histochem Cytochem,28(1):43-53 1995 Author:Ota H, Katsuyama T, Akamatsu T, Fujimori Y, Matsuzawa K, Ishii K, Honda T, Nakayama J, Furihata K, Ono K, Maeda K
Trophinin and tastin, a novel cell adhesion molecule complex with potential involvement in embryo implantation Genes Dev,9:1199-1210 1995 Author:Fukuda MN, Sato T, Nakayama J, Klier G, Mikami M, Aoki D, Nozawa S
Frequently relapsing minimal change nephrotic syndrome with natural killer cell deficiency prior to the overt relapse of Hodgkin’s disease Pediatr Nephorol,9(5):619-620 1995 Author:Mori T, Yabuhara A, Nakayama J, Kitahara M, Washizawa K, Kasai S, Komiyama A
Monoclonal antibody E6G6 recognizes glycolipids as a differentiation antigen in shope carcinoma cells Cancer Lett,81(2):221-228 1994 Author:Kyogashima M, Inoue M, Isono T, Nakayama J, Seto A
Expression of Forssman antigen in human large intestine J Histochem Cytochem,42(5):659-665 1994 Author:Ono K, Hattori H, Uemura K, Nakayama J, Ota H, Katsuyama T
Proposal for an aeroschema (modified Aerokey II) for the identification of cllinical Aeromonas species Med Sci Res,22(9):617-619 1994 Author:Furuwatari C, Kawakami Y, Akahane T, Hidaka E, Okimura Y, Nakayama J, Furihata K, Katsuyama T
Liver injury following normothermic ishemia in steatotic rat liver Hepatology,20(5):1287-1293 1994 Author:Hui A, Kawasaki S, Makuuchi M, Nakayama J, Ikegami T, Miyagawa S
Establishment of Epstein-Barr virus-associated lymphoma cell line SUBL with t(2;3)(p11;q27) from a liver transplant patient Cancer Genet Cytogenet,71(2):155-163 1993 Author:Yoshizawa K, Kiyosawa K, Yamada S, Furuta K, Yabu K, Kitano K, Akamatsu T, Nakayama J, Katsuyama T, Matsunami H, Kawasaki S, Makuuchi M, Nanba K, Furuta S
Polysialosyl glycoconjugates defined by monoclonal antibody M6704 are expressed in human gliomas and embryonic neurons J Histochem Cytochem,41(10):1563-1572 1993 Author:Nakayama J, Katsuyama T, Sugiyama E, Hirabayashi Y
Primary hyperparathyroidism masquerading as immobilization hypercalcemia -report of an illustrative case Endocrine J,40(1):35-39 1993 Author:Monno S, Yokozawa T, Mizushima Y, Nakayama J,Ohgaku S, Kato H, Takasu N, Kobayashi M
Organizing differentiation of tumorcells of villous adenomas of the large intestine Acta Histochem Cytochem,26(2):117-125 1993 Author:Ota H, Nakayama J, Fujimori Y, Furihata K, Katsuyama T, Moriyama S, Hata S, Ono K
Immunohistochemical demonstration of glycoconjugates bearing the type 2 chain-backbone structurein human fetal, normal and neoplastic gastrointestinal tract Histochemistry,97(4):303-310 1992 Author:Nakayama J, Ota H, Katsuyama T, Kanai M, Taki T, Hirabayashi Y, Suzuki Y
Aberrant expression of blood group H-antigen in shope carcinoma cells Cancer Lett,66(3):175-181 1992 Author:Kyogashima M, Inoue M, Nakayama J, Seto A
Distribution of retinol-binding protein in the human digestive tract Virchows Arch B,61(5):315-322 1992 Author:Kameko M, Ota H, Ishii K, Nakayama J, Katsuyama T, Kanai M, Tsutsumi Y
Histochemical demonstration of gastrointestinal mucins in ovarian mucinous cystadenoma Acta Pathol Jpn,42(2):104-110 1992 Author:Shiozawa T, Tsukahara Y, Ishii K, Ota H, Nakayama J, Katsuyama T
The antitumor activity and immunosuppressive effects of 5-fluorouracil suppositories in rectal cancer patients Surg Today,22(3):221-225 1992 Author:Adachi W, Sugenoya A, Horigome N, Takahashi C, Iida F, Nakayama J
Adenocarcinoma of the cervical oesophagus arising from ectopic gastric mucosa - the histochemical determination of its origin Virchows Arch A,419(2):159-164 1991 Author:Ishii K, Ota H, Nakayama J, Katsuyama T, Matsuzawa K, Honda T, Akamtsu T
A new monoclonal antibody directed to sialyl-alpha2-3 lactoneotetraosylceramide and its application for detection of human gastrointestinal neoplasms J Biochem (Tokyo),109(2):354-360 1991 Author:Suzuki Y, Nishi H, Hidari K, Hirabayashi Y, Matsumoto M, Kobayashi T, Watari S, Yasuda T, Nakayama J, Maeda H, Katsuyama T, Kanai M, Kiso M, Hasegawa A
Immunohistochemical reactivity of antikeratan sulfate monoclonal antibody 5D4 to various conditions of human endometrial tissues and its application as a useful marker for identifying endometrial epithelia Gynecol Obstet Invest,32(4):239-242 1991 Author:Shiozawa T, Tsukahara Y, Nakayama J, Ishii K, Katsuyama T
Immunohistochemical localization of blood group substances in normal and neoplastic endometrial tissues - with special reference to type 1 core chain expression Gynecol Obstet Invest,32(3):185-188 1991 Author:Shiozawa T, Tsukahara Y, Nakayama J, Ishii K, Katsuyama T
Lectin histochemistry of the normal human endometrium and endometrial adenocarcinoma Acta Histochem Cytochem,24(2):233-240 1991 Author:Shiozawa T, Tsukahara Y, Nakayama J, Katsuyama T
A dual staining method for identifying mucins of different gastric epithelial mucous cells Histochem J,23(1):22-28 1991 Author:Ota H, Katsuyama T, Ishii K, Nakayama J, Shiozawa T, Tsukahara Y
Griffonia simplicifolia agglutinin-2-binding glycoprotein as a novel carbohydrate antigen of human colonic carcinoma Jpn J Cancer Res,81(4):388-395 1990 Author:Nakayama J, Okano A, Maeda H, Miyachi M, Ota H, Katsuyama T, Kanai M
Accumulation of gangliosides with N-acetylneuraminosyl(α2-6)lactosamine structure in primary human hepatoma Cancer Res,50(4):1284-1290 1990 Author:Taki T, Yamamoto K, Takamatsu M, Ishii K, Myoga A, Sekiguchi K, Ikeda I, Kurata K, Nakayama J, Handa S, Matsumoto M
講演・口頭発表等 Preventive role of the gland mucin-specific αGlcNAc in gastric cancer development The 12th China-Japan Joint Seminar on Histochemictry and Cytochemistry 2017 Presenter:Nakayama J
Preventive roles of gastric gland mucin in pathogenesis of gastric cancer The 43rd International Symposium of The Princess Takamatsu Cancer Research Fund 2012 Presenter:Nakayama J
Dual roles of gastric gland mucin-specific O-glycan on prevention of gastric cancer 14th International Congress of Histochemistry and Cytochemistry. 2012 Presenter:Nakayama J
Interaction of Helicobacter pylori and O-glycans in stomach Glycobiology Japan-Netherland Joint Seminar 2011 2011 Presenter:Nakayama J
A subtype of human gastric mucins expressing alpha1,4-GlcNAc-capped O-glycans functions as a natural antibiotic against Helicobacter pylori infection US/Japan Glyco 2004 2004 Presenter:Nakayama J, Kawakubo M, Ito Y, Kobayashi M, Fukuda NM, Fukuda M, Katsuyama T
Detection of circulating gastric cancer cells using real-time RT-PCR targeted α1,4-N-Acetylglucosaminyltransferase messenger RNA The 18th International Congress of Clinical Chemistry and Laboratory Medicine 2002 Presenter:Nakayama J, Shimizu F, Zhang MX, Fukuda M, Katsuyama T
α1,4-N-Acetylglucosaminyltransferase and gastric cancer The 32nd International Symposium of the Princess Takamatsu Cancer Research Fund 2001 Presenter:Nakayama J, Shimizu F, Zhang MX, Fukuda M, Katsuyama T
Expression cloning of a human α-1,4-N-acetylglucosaminyltransferase that forms GlcNAcα1-4Galβ-R, a unique glycan for the gastric gland mucous cell-type mucin XVth International Symposium on Glycoconjugates 1999 Presenter:Nakayama J, Yeh JC, Misra A, Ito S, Katsuyama T, Fukuda M
Developmentally regulated-expression of polysialic acid in nervous system directed by two polysialyltransferases, PST and STX 10th International Congress of Histochemistry and Cytochemistry 1996 Presenter:Nakayama J, Angata K, Ong E, Onishi N, Katsuyama T, Arai Y, Fukuda M
A newly cloned polysialyltransferase forms the embryonic form of N-CAM that facilitates neurite outgrowth XIIIth International Symposium on Glycoconjugates 1995 Presenter:Nakayama J, Fukuda MN, Fredette B, Ranscht B, Fukuda M
MISC Limitation in defining ablation line by maginified endoscopic imaging for endoscopic submucosal resection of gastric adenocarcinoma of fundic gland type as revealed by 3D redonstruction images of gastric tissue specimens. J Can Assoc Gastroenterol,1:137 2018 Author:Yamada S, Matsuura H, Nakayama J
Shinshu Brain Resource Net Neuropathology ,36:600 2016 Author:Oyanagi K, Yamada M, Hineno A, Yahikozawa H, Ushiyama M, Miki J, Kanno H, Nakayama J, Makishita H, Inoue K, Ohara S, Hayashida K, Kayanuma K, Yamamoto K, Yasude T, Hashimoto T, Yoshida K, Ikeda S-i
Interleukin-1β suppression in Blau syndrome: comment on the article by Martin et al. Arthritis Rheum,60:2544 2009 Author:Masumoto J, Yamazaki T, Ohta K, Nakayama J, Agematsu K
Sulfation patterns of keratan sulphate in different macular corneal dystrophy immunophenotypes using three different probes Br J Ophthalmol,92:1434 2008 Author:Saito T, Nishida K, Nakayama J, Akama TO, Fukuda MN, Watanabe K, Quantock AJ, Maeda N, Watanabe H, Tano Y
Malignant granular cell tumor of the esophagus Virchows Arch,444:304 2004 Author:Yoshizawa A, Ota H, Sakaguchi N, Kanai S, Nakayama J, Matsuzawa K, Tsuzuki S, Takada R, Miyazawa F, Kasahara H, Katsuyama T
Relation of H pylori to gastric mucins andgastric surface mucous gel layer Gut,48:869 2001 Author:Ota, H; Nakayama, J; Shimizu, T; Nakayama, J; Graham, DY; Katsuyama, T
Association of smoking with apoptosis-regulated proteins (Bcl-2, Bax and p53) in resected non-small-cell lung cancers Int J Cancer,91:267 2001 Author:Hanaoka, T; Nakayama, J; Mukai, J; Irie, S; Yamanda, T; Sato, TA
Gastric gland mucous cells circulate in peripheral blood after endoscopic biopsy of the gastric mucosa Am J Gastroenterol,10:3017 2000 Author:Shimizu, F; Nakayama, J; Sugiyama, A; Kawasaki, S; Katsuyama, T
研究者総覧
