KAWAMURA, Atsushi | Shinshu University Researcher Directory

Academic Organization		TEL	+81265-77-1400
Education and Research Organization	Interdisciplinary Cluster for Cutting Edge Research Institute for Biomedical Sciences	FAX
Position	Assistant Professor	Mail Address	a_kawamura＠shinshu-u.ac.jp
Address	8304, Minamiminowa-Village, Kamiina-County 399-4598	Web site	https://makabelab8304.wixsite.com/home

Profile

Research Field: Natural Products Chemistry
Medicinal Chemistry
Keywords:Isolation and Structure Determination , Structure Activity Relationship Study , Synthetic Organic Chemistry , Antibody-Drug Conjugate

Current Subject: Isolation and Structure Determination of Natural Products
Keywords:Isolation and Structure Determination , Bioactive Natural Products
Total Synthesis of Natural Products
Keywords:Synthetic Organic Chemistry

Academic Societies: Academic Societies
The Chemical Society of Japan

Academic Background: Graduate School
University of Tsukuba , (Doctoral Programs in Chemistry , Graduate School of Pure and Applied Sciences) , 2016
University of Tsukuba , (Doctoral Programs in Chemistry , Graduate School of Pure and Applied Sciences) , 2013

College
University of Hyogo , (School of Science) , 2011

Degree
Ph.D. in Chemistry , University of Tsukuba

Awards: 2018 , Postdoctoral Fellowship, The UEHARA Memorial Foundation
2014 , Best Presentation Award, 58th Symposium on the Chemistry of Terpenes, Essential Oils, and Aromatics (TEAC 2014)

Research Career: Research Career
2019- , Assistant Professor, Interdisciplinary Cluster for Cutting Edge Research, Institute for Biomedical Sciences
2019-2019 , Postdoctoral Fellow, Graduate School of Bioagricultural Sciences, Nagoya University
2018-2019 , Postdoctoral Associate, Department of Medicinal Chemistry, University of Florida
2017-2018 , Postdoctoral Fellow, Graduate School of Pharmaceutical Sciences, University of Tokyo
2016-2017 , Postdoctoral Fellow, Graduate School of Pharmaceutical Sciences, University of Tokyo (Research Fellow of the Japan Society for the Promotion of Science, PD)
2016-2016 , Postdoctoral Fellow, Faculty of Pure and Applied Sciences, University of Tsukuba (Research Fellow of the Japan Society for the Promotion of Science, PD)
2015-2016 , Research Fellow of the Japan Society for the Promotion of Sciences (DC2)

Overseas Education
2018-2019 , Postdoctoral Associate, Department of Medicinal Chemistry, University of Florida

Research

Books, Articles, etc.: Articles
Concise Synthesis of Procyanidin B2 3,3 ''-Digallate Using Yb(OTf)(3)-Mediated Self-Condensation
SYNLETT,33(11):1071-1074 2022
Author:Yuuri Tanaka, Shu-hei Kobayashi, Yasunao Hattori, Atsushi Kawamura*, Hidefumi Makabe*
Keywords:procyanidin; Lewis acid; condensation; epicatechin gallate; natural products;

Synthesis of (+)-solenopsin via Pd-catalyzed N-alkylation and cyclization
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY,85(2):223-227 2021
Author:Kana Suzuki, Yasunao Hattori, Atsushi Kawamura, Hidefumi Makabe*

Synthesis of (+)-Muconin via Diastereoselective Oxypalladation
JOURNAL OF ORGANIC CHEMISTRY,86(6):4859-4866 2021
Author:Makoto Sugimoto, Sayaka Nosho, Gen Hikosaka, Yasunao Hattori, Koji Umezawa, Atsushi Kawamura, Hidefumi Makabe*

Sulfonamides as new hydrogen atom transfer (HAT) catalysts for photoredox allylic and benzylic C-H arylations
CHEMICAL COMMUNICATIONS,54(26):3215-3218 2018
Author:Hirotaka Tanaka, Kentaro Sakai, Atsushi Kawamura, Kounosuke Oisaki*, Motomu Kanai*

Aplysiasecosterols B and C: two new 9,11-secosteroids with a cis-fused 1,4-quinone structure from the sea hare Aplysia kurodai
TETRAHEDRON LETTERS,57(8):858-860 2016
Author:Masaki Kita*, Atsushi Kawamura, Hideo Kigoshi*

Aplysiasecosterol A: A 9,11-Secosteroid with an Unprecedented Tricyclic γ-Diketone Structure from the Sea Hare Aplysia kurodai
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION,54(24):7073-7076 2015
Author:Atsushi Kawamura, Masaki Kita*, Hideo Kigoshi*

Stylissatin A, a cyclic peptide that inhibits nitric oxide production from the marine sponge Stylissa massa
TETRAHEDRON LETTERS,54(50):6826-6828 2013
Author:Masaki Kita*, Baro Gise, Atsushi Kawamura, Hideo Kigoshi*

Anion polarity-induced dual oxidation states in a dual-layered purely organic paramagnetic charge-transfer salt, (TTF)(3)(PO-CON(CH3)C2H4SO3)(2), where PO=2,2,5,5-tetramethyl-3-pyrrolin-1-oxyl free radical
CRYSTENGCOMM,13(17):5281-5284 2011
Author:Hiroki Akutsu*, Atsushi Kawamura, Jun-ichi Yamada, Shin'ichi Nakatsuji, Scott S. Turner

Presentations
アメフラシ由来の新規 aplaminone 誘導体の発見と分子ネットワーク解析によるその起源の解明
日本化学会第102春季年会 2022(Mar. 24)
Presenter:日置祐介, 栩野安友花, 佐藤達也, 岩尾豊紀, 河村篤, 北将樹

アコラン型セスキテルぺノドの合成研究
日本化学会第102春季年会 2022(Mar. 24)
Presenter:亀山勇樹, 河村篤, 真壁秀文

Elucidation of the origins of marine natural products: Investigation of aqueous chemical constituents of the sea hare Aplysia kurodai
The International Chemical Congress of Pacific Basin Societies 2021(Dec. 17)
Presenter:Yusuke Hioki, Atsushi Kawamura, Masaki Kita

Homogeneous Antibody-Drug Conjugates (ADCs) by a Tryptophan-Selective Protein Bioconjugation
10th International Peptide Symposium 2018(Dec. 06)
Presenter:Kounosuke Oisaki, Takashi Ishiyama, Atsushi Kawamura, Kuniko Saiki, Yuki Kobayashi, Katsuya Maruyama, Yohei Seki, Keita Iguchi, Masaru Mitsuda, Motomu Kanai

Tryptophan-Targeted Homogeneous Antibody-Drug Conjugates
The 9th International Forum on Chemistry of Functional Organic Chemicals (IFOC-9) 2018(Nov. 09)
Presenter:Katsuya Maruyama, Takashi Ishiyama, Atsushi Kawamura, Kuniko Saiki, Yuki Kobayashi, Yohei Seki, Keita Iguchi, Masaru Mitsuda, Kounosuke Oisaki, Motomu Kanai

トリプトファン結合型抗体–薬物複合体の開発
日本ケミカルバイオロジー学会第13回年会 2018(Jun. 13)
Presenter:河村篤, 石山隆史, 斎木邦子, 丸山勝也, 関陽平, 井口恵太, 満田勝, 生長幸之助, 金井求

光触媒-スルホンアミド HAT 触媒ハイブリッドを用いる C-H アリール化反応
日本薬学会第138年会 2018(Mar. 26)
Presenter:田中博隆, 坂井健太郎, 河村篤, 生長幸之助, 金井求

Isolation and structure analysis of novel 9,11-seco-steroids from the sea hare Aplysia kurodai
2015 International Chemical Congress of Pacific Basin Societies 2015(Dec. 18)
Presenter:Atsushi Kawamura, Masaki Kita, Hideo Kigoshi

海洋軟体動物アメフラシ由来の新規 9,11-セコステロイド化合物の単離・構造決定
日本化学会第95春季年会 2015(Mar. 28)
Presenter:河村篤, 北将樹, 木越英夫

海洋軟体動物アメフラシ由来の新規 9,11-セコステロイド化合物の単離・構造決定
第58回香料・テルペンおよび精油化学に関する討論会 2014(Sep. 21)
Presenter:河村篤, 北将樹, 木越英夫

Isolation and Structure Analysis of Unique Secondary Metabolites from Marine Invertebrates
International Conference on the Chemistry of Antibiotics and other bioactive compounds (ICCA-13) 2013(Sep. 25)
Presenter:Atsushi Kawamura, Baro Gise, Masaki Kita, Hideo Kigoshi

Isolation and Structure Analysis of Novel Secondary Metabolites from Marine Invertebrates (英語公演)
日本化学会第94春季年会 2013(Mar. 27)
Presenter:Atsushi Kawamura, Masaki Kita, Hideo Kigoshi

海洋生物由来の抗炎症活性物質に関する研究
日本化学会第93春季年会 2013(Mar. 25)
Presenter:河村篤, GISE BARO, 北将樹, 木越英夫

Study of Anti-inflammatory Substances from Marine Origin
3rd International Symposium on Creation of Functional Materials 2012(Dec. 10)
Presenter:Atsushi Kawamura, Baro Gise, Masaki Kita, Hideo Kigoshi

海洋生物由来の抗腫瘍性および抗炎症活性物質に関する研究
日本化学会第92春季年会 2012(Mar. 28)
Presenter:河村篤, GISE BARO, 北将樹, 木越英夫

新しい安定有機ラジカル誘導体アニオン PO-COAC2H4SO3 (A = O, S, N(CH3))とその電荷移動塩の開発
日本化学会第91春季年会 2011(Mar. 28)
Presenter:河村篤, 小林憲二, 圷広樹, 山田順一, 中辻慎一

Research Grants: Grants‐in‐aid for Scientific Research(Research Representative)
2021 - 2023 , C(sp3)-H活性化反応を鍵としたRhodatinの全合成と誘導体合成法の構築 , 日本学術振興会科学研究費助成事業若手研究
2015 - 2016 , 新規海洋産天然物アプリシアセコステロールＡ, Ｂ, Ｃに関する研究 , 特別研究員奨励費

Other
2022 - 2023 , デュアル触媒系によるクロスカップリング反応を鍵反応としたプロアントシアニジン類の新規合成法の開発
2021 - 2022 , ケロウジ (Sarcodon scabrosus) に含まれるシアタン化合物の探索と炎症抑制活性の研究
2020 - 2021 , アルツハイマー病の治療、および予防を志向した小豆由来アミロイドβ凝集阻害活性成分の探索

Shinshu University Researcher Directory

KAWAMURA Atsushi

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KAWAMURA　Atsushi