OYANAGI Kiyomitsu
School of Medicine Department of Brain Disease Research
Professor
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Paper
- The neostriatum in polyglutamine diseases: preferential decrease of large neurons in dentatorubral-pallidoluysian atrophy and Machado-Joseph disease, but of small neurons in Huntington disease
Oyanagi K, Shimizu H, Yamada M, Kakita A
Neuropathology, 42, 274-281, 2022 - The large neuron involvement in the neostriatum in Lewy body diseases
Oyanagi K, Hayashi H, Yamada M, Kakita A
Neuropathology, 42, 459-463, 2022 - Pathologic basis of the preferential thinning of corpus callosum in adult-onset leukoencephalopathy with axonal spheroids and pigmented glia (ALSP)
Kinoshita M, Oyanagi K, Kondo Y, Ishizawa K, Ishihara K, Yoshida M, Inoue T, Mitsuyama Y, Yoshida K, Yamada M, Sekijima Y, Ikeda S
eNeurologicalSci, 22, 100310, 2021 - Spread of vimentin-immunopositive cells within the plaque-like lesion in the spinal anterior horn of a patient with post-poliomyelitis syndrome
Hineno A, Oyanagi K, Yoshida T, Sakai Y, Kannno H, Sekijima Y
Neuropathology, 41, 406-411, 2021 - Activation of the unfolded protein response and proteostasis disturbance in parkinsonism-dementia of Guam
Verheijen BM, Lussier C, Müller-Hübers C, Garruto RM, Oyanagi K, Braun RJ, van Leeuwen FW
Journal of Neuropathology and Experimental Neurology, 79, 34-45, 2020
- Expression of mutant ubiquitin and proteostasis impairment in Kii amyotrophic lateral sclerosis / parkinsonism-dementia complex brains
Verheijen BM, Morimoto S, Sasaki R, Oyanagi K, Kokubo Y, Kuzuhara S, van Leeuwen FW
Journal of Neuropathology and Experimental Neurology, 79, 902-907, 2020 - Neuromyelitis optica spectrum disorder with massive basal ganglia involvement: a case report.
Ohara S, Miyahira TA, Oguchi K, Takei YI, Yanagimura F, Kawachi I, Oyanagi K, Kakita A.
BMC Neurol., 19(1), 351, 30 Dec. 2019 - Retinal Vasculopathy With Cerebral Leukodystrophy: Clinicopathologic Features of an Autopsied Patient With a Heterozygous TREX 1 Mutation.
Saito R, Nozaki H, Kato T, Toyoshima Y, Tanaka H, Tsubata Y, Morioka T, Horikawa Y, Oyanagi K, Morita T, Onodera O, Kakita A.
J Neuropathol Exp Neurol., 78(2), 181-186, Feb. 2019 - Atypical lower motor neuron disease with enlargement of Nissl substance: report of an autopsy case
Shintaku M, Kaneda D, Oyanagi K
CLINICAL NEUROPATHOLOGY, 37(2), 74-81, 2018 - Dysfunction of protein quality control in parkinsonism-dementia compex of Guam
Verheijen BM, Oyanagi K, van Leeuwen FW
Froniiers of Neurology, 9, 173, 2018
- Adult onset leukoencephalopathy with axonal spheroids and pigmented glia (ALSP) and Nasu-Hakola disease: Lesion staging and dynamic changes of axons and microglial subsets.
Oyanagi K, Kinoshita M, Suzuki-Kouyana E, Inoue T, Nakahara A, Tokiwai M, Arai N, Satoh JI, Aoki N, Jinnai K, Yazawa I, Arai K, Ishihara K, Kawamura M, Ishizawa K, Hasegawa K, Yagisita S, Amano N, Yoshida K, Terada S, Yoshida M, Akiyama H, Mitsiyama Y, Ikeda S.
Brain Pathol, 27, 748-769, 2017 - An autopsy case of respiratory failure induced by repetitive cervical spinal cord damage due to abnormal movement of the neck in athetoid palsy
Takei Y, Koshihara H, Oguchi K, Oyanagi K, Ohara S
INTERNAL MEDICINE, 56, 1425-1430, 2017 - Novel intracytoplasmic inclusions immunopositive for phosphorylated-TDP43 and cystatin C in anterior horn cells in a case of sporadic amyotrophic lateral sclerosis
Shintaku M, Kaneda D, Oyanagi K
Neuropathology, 37, 526-534, 2017 - Deposition of mutant ubiquitin in parkinsonism-dementia complex of Guam
Verheijen BM, Hashimoto T, Oyanagi K, van Leeuwen FW
Acta Neuropathologica Communications, 5, 82, 2017 - Shinshu Brain Resource Net.
Oyanagi K, Yamada M, Hineno A, Yahikozawa H, Ushiyama M, Miki J, Kanno H, Nakayama J, Makishita H, Inoue K, Ohara S, Hayashida K, Kayanuma K, Yamamoto K, Yasude T, Hashimoto T, Yoshida K, Ikeda SI.
Neuropathology, 36(6), 600-601, Dec. 2016 - Axonal TDP-43 aggregates in sporadic amyotrophic lateral sclerosis.
Onozato T, Nakahara A, Suzuki-Kouyama E, Hineno A, Yasude T, Nakamura T, Yahikozawa H, Watanabe M, Kayanuma K, Makishita H, Ohara S, Hashimoto T, Higuchi K, Sakai T, Asano K, Hashimoto T, Kanno H, Nakayama J, Oyanagi K.
Neuropathol Appl Neurobiol, 42(6), 561-72, Oct. 2016 - Clinicopathological characteristics of patients with amyotrophic lateral sclerosis resulting in a totally locked-in state (communication Stage V).
Hayashi K, Mochizuki Y, Takeuchi R, Shimizu T, Nagao M, Watabe K, Arai N, Oyanagi K, Onodera O, Hayashi M, Takahashi H, Kakita A, Isozaki E.
Acta Neuropathol Commun, 4(1), 107, Sep. 2016 - Hippocampal sclerosis in the parkinsonism-dementia complex of Guam: quantitative examination of neurons, neurofibrillary tangles, and TDP-43 immunoreactivity in CA1.
Oyanagi K, Yamazaki M, Hashimoto T, Asakawa M, Wakabayashi K, Takahashi H.
Neuropathology, 35(3), 224-35, Jan. 2015 - Marked preservation of the visual and olfactory pathways in ALS patients in a totally locked-in state
Oyanagi K, Mochizuki Y, Nakayama Y, Hayashi K, Shimizu T, Nagao M, Hashimoto T, Yamazaki M, Matsubara S, Komori T
CLINICAL NEUROPATHOLOGY, 34, 267-274, 2015 - Predictors of impaired communication in amyotrophic lateral sclerosis patients with tracheostomy-invasive ventilation.
Nakayama Y, Shimizu T, Mochizuki Y, Hayashi K, Matsuda C, Nagao M, Watabe K, Kawata A, Oyanagi K, Isozaki E, Nakano I.
Amyotroph Lateral Scler Frontotemporal Degener, 17(1-2), 38-46, 2015 - “Gliomatosis encephali” as s novel category of brain tumor by the first autopsy case report of gliomatosis cerebelli.
Nakahara A, Yoshida T, Yazawa M, Ehara T, Nakayama J, Kakita A, Ogura R, Asakawa M, Suzuki-Kouyama E, Oyanagi K
Neuropathology, 34, 295-303, 2014 - An autopsy case of familial amyotrophic lateral sclerosis with FUS R521G mutation.
Mochizuki Y, Kawata A, Hashimoto T, Akiyama H, Kawakami H, Komori T, Oyanagi K, Mizutani T, Matsubara S
Amyotroph Lateral Scler Frontotemporal Degener, 15, 305-308, 2014 - Comparative study of fibrin and chemical synthetic sealant on dural regeneration and brain damage.
Ito K, Horiuchi T, Oyanagi K, Nomiyama T, Hongo K
Neurosurg, 2014 - Distinctive features of degenerating Purkinje cells in spinocerebellar ataxia type 31.
Yoshida K, Asakawa M, Suzuki-Kouyama E, Tabata K, Shintaku M, Ikeda S, Oyanagi K
Neuropathology, 34, 261-267, 2014 - Hippocampal sclerosis in the parkinsonism-dementia complex of Guam: quantitative examination of neurons, neurofibrillary tangles, and TDP-43 immunoreactivity in CA1.
Oyanagi K, Yamazaki M, Hashimoto T, Asakawa M, Wakabayashi K, Takahashi H.
Neuropathology, 2014 - Development of primary central nervous lymphoma associated with human immunodeficiency virus and JC virus infection.
Kawakami T, Sakai K, Mimura Y, Senoo Y, et al.
J Clin Exp Hematopathol, 2014 - Mannitol infusion immediately after reperfusion suppresses the development of focal cortical infarction after temporary cerebral ischemia in gerbils.
Ito U, Hakamata Y, Watabe K, Oyanagi K
Neuropathology, 34(4), 360-369, 2014
- Zinc Transporters (ZnT3 and 6) Are Downregulated in the Spinal Cords of Patients with Sporadic Amyotrophic Lateral Sclerosis.
Kaneko M, Noguchi T, Ikegami S, Oyanagi K, Inuzuka T, Takahashi H, Hozumi I.
J Neurosci Res, 93(2), 370-379, 2014 - Pathological features of FTLD-FUS in a Japanese population: analyses of nine cases
Kobayashi Z, Kawakami I, Arai T, Yokota O, Tsuchiya K, Kondo H, Shimomura Y, Haga C, Aoki N, Hasegawa M, Hosokawa M, Oshima K, Niizato K, Ishizu H, Terada S, Onaya M, Ikeda M, Oyanagi K, Nakano I, Murayama S, Akiyama H, Mizusawa H
J Neurol Sci, 335, 89-95, 2013 - Hereditary diffuse leukoencephalopathy with axonal spheroids caused by R782H mutation in CSF1R: Case report
Kinoshita, M., Yoshida, K., Oyanagi, K., Hashimoto, T., Ikeda, S
J Neurol Sci, 318, 115-118, 2012 - Familial ALS with FUS P525L mutation: two Japanese sisters with multiple system involvement
Mochizuki Y, Isozaki E, Takao M, Hashimoto T, Shibuya M, Arai M, Hosokawa M, Kawata A, Oyanagi K, Mihara B, Mizutani T
J Neurol Sci, 323, 85-92, 2012 - Distinctive clinicopathological features of 2 large families with amyotrophic lateral sclerosis having L106V mutation in SOD1 gene
Hineno A, Nakamura A, Shimojima Y, Yoshida K, Oyanagi K, Ikeda S
J Neurol Sci, 319, 63-74, 2012 - Radiologic and neuropathologic findings in patients in afamily with dentatorubral-pallidoluysian atrophy
Sunami Y, Koide R, Arai N, Yamada M, Mizutani T, Oyanagi K
Ameerican Journal of Neuroradiology, 32, 109-114, 2011 - Temporary focal cerebral ischemia results in swollenn astrocytic end-feet that compress microvessels and lead to focal cortical infarction
Ito U, Hakamata Y, Kawakami E, Oyanagi K
Journal of Cerebral Blood Flow and Metabolism, 31, 328-338, 2011 - Survival motor neuron (SMN) protein in the spinal anterior horn cells of patients with sporadic amyotrophic lateral sclerosis
Piao Y, Hashimoto T, Takahama S, Kakita A, Komori T, Morita T, Takahashi H, Mizutani T, Oyanagi K
Brain Research, 1372, 152-159, 2011 - Distinctive expression of midkine in the repair period of rat brain during neurogenesis : Immunohistochemical and immunoelectron microscopic observations
Kikuchi-Horie, K; Kawakami, E; Kamata, M; Wada, M; Hu, JG; Nakagawa, H; Ohara, K; Watabe, K; Oyanagi, K
J.Neurosci Res, 75(5), 678-687, 2004 - Neuropathology with clinical correlations of sporadic amyotrophic lateval sclerosis: 102 autopsy cases examined between 1962 and 2000
Piao, YS; Wakabayashi, K; Kakita, A; Yamada, M; Hayashi, S; Morita, T; Ikuta, F; Oyanagi, K; Takahashi, H
BRAIN PATHOLOGY, 12, 10-22, 2003 - Temporal profile of experimental ischemic edema after threshold amount of insult to induce infarction-ultrastructure, gravimetry and Evans' blue extravasation
Ito U, Kuroiwa T, Hanyu S, Hatanaka Y, Kawakami E, Nakano I, Oyanagi K
Acta Neurochir, 86(Suppl), 131-135, 2003 - Topical instillation of ciliary neurotrophic factor inhibits retinal degeneration in streptozotocin -induced diabetrc rats
Aizu, Y; Katayama, H; Takahama, S; Hu, JG; Nakagawa, H; Oyanagi, K
Neuro Report, 14(16), 2067-2071, 2003 - Widespread vertebral and venous plexus metastasis of prostatic carcinoma presenting wedge-shaped radial lesions in the spinal cord
Oyanagi, K; Ogata, K; Takeda, S; Horikawa, Y; Kawakami, E; Morita, T
Neuropathology, 23(4), 296-300, 2003 - Histone deacetylase activity is retained in primary neurons expressing mutant huntingtin protein
Hoshino, M; Tagawa, K; Okuda, T; Murata, M; Oyanagi, K; Arai, N; Mizutani, T; Kanazawa, I; Wanker, EE; Okazawa, H
J Neurochemistry, 87(1), 257-267, 2003 - Pathological involvement of the motor neuron system and hippocampal formation in motor neuron disease -inclusion dementia
Toyoshima, Y; Piao, YS; Tan, CF; Morita, M; Tanaka, M; Oyanagi, K; Okamoto, K; Takahashi, H
Acta Neuropathologica, 106(1), 50-56, 2003 - Degeneration of retinal neuronal processes and pigment epithelium in the early stage of the streptozotocirl-diabetic rats
Aizu, Y; Oyanagi, K; Hu, JG; Nakagawa, H
Neuropathology, 22(3), 161-170, 2002 - Alteration of midkine expressim in the isehemic brain of humans
Wada, M; Kamata, M; Aizu, Y; Morita, T; Hu, JG; Oyanagi, K
J Neurological Sciences, 200(1-2), 67-73, 2002 - Enhanced SUMOylation in Polyglutamine disease
Ueda, H; Goto, J; Hashida, H; Lin, X; Oyanagi, K; Kawano, H; Zoghbi, HY; Kanazawa, I; Okazawa, H
BBRC, 293(1), 307-313, 2002 - Establishment and characterization of immortalized Schwann cells from murine model of Niemann-Pick disease type C (spm/spm).,
Watabe,K., Ida,H., Uehara,K., Oyanagi,K., Sakamoto,T., Tanaka,J., Garver,W.S., Miyawaki,S., Ohno,K., Eto,Y.,
J Peripher Nerv Syst, 6(2), 85-94, 2001 - Substantia nigra in progressive supranuclear palsy, corticobasal degeneration, and parkinsonism-dementia complex of Guam: specific pathological features.,
Oyanagi,K., Tsuchiya,K., Yamazaki,M., I,keda,K.,
J Neuropathol Exp Neurol, 60(4), 393-402, 2001 - Expression of calbindin D-28k and parvalbumin in cerebral cortical dysgenesis induced by administration of ethylnitrosourea to rats at the stage of neurogenesis,
Oyanagi,K., Kakita,A., Kawasaki,K., Hayashi,S., Yamada,M.,
Acta Neuropathologica, 101(4), 375-382, 2001 - Distribution of basal ganglia lesions in generalized variant of Pick's disease: a clinicopathological study of four autopsy cases,
Tsuchiya,K., Ishizu,H., Nakano,I., Kita,Y., Sawabe,M.,Haga,K., Kuyama,K., Nishinaka,T., Oyanagi,K., Ikeda,K., kuroda,S.,
Acta Neuropathologica, 102(5), 441-448, 2001 - Progressive supranuclear palsy on Guam,
Yamazaki,M., Makifuchi,T., Chen, K-M., Mori,O., Katayama,Y., Takahashi,H., Oyanagi,K.,
Acta Neuropathologica, 102(5), 510-514, 2001 - Adenoviral gene transfer of glial cell line-derived neurotrophic factor to injured adult motoneurons.,
Watabe,K., Sakamoto,T., Ohashi,T., Kawazoe,Y., Oyanagi,K., Takeshima,T., Inoue,K., Eto,Y., Kim,S.U.,
Hum Cell, 14, 7-15, 2001 - Neuronal nuclear alterations in dentatorubural-pallidoluysian atrophy:ultrastructural and morphometric studies of the cerebellar granule cells
Takahashi, H; Egawa, S; Piao, YS; Hayashi, S; Yamada, M; Shimohata, T; Oyanagi, K; Tsuji, S
Brain Research, 919(1), 12-19, 2001 - Endothelin-1 in the brain of patients with galactosialidosis: its abnormal increase and distribution pattern
Itoh, K., Oyanagi, K., Takahashi, H., Sato, T., Hashizume, N., ShimmOtO, M., SakUraba, H.,
Annals of Neurol, 47(1), 122-126, 2000 - alpha-synuclein inclusions in amygdala in the brains of patients with the parkinsonism-dementia complex of Guam
Yamazaki, M., Arai, Y., Baba, M., Iwatsubo, T., Mori, O., Katayama, Y., Oyanagi, K.,
J Neuropathol Exp Neurol, 59(7), 585-591, 2000 - Parkinsonism, dementia and vertical gaze palsy in a Guamanian with atypical neuroglial degeneration
Oyanagi, K., Chen, K-M., Craig, U.K., Yamazaki, M., Perl, D.P.,
Acta Neuropathol, 99(1), 73-80, 2000 - Bunina bodies in amyotrophic lateral sclerosis on Guam: a histochemical, immunohistochemical and ultrastructural investigation
Wada,M.,Uchihara,T.,Nakamura,A.,Oyanagi,K.,
Acta Neuropathologica, 98(2), 150-156, 1999 - Variant Gerstmann-Straussler syndrome with the P1O5L pion gene mutation: an unusual case with nigral degeneration and widespread neurofibrillary tan・・・
Yamazaki, M., Oyanagi, K., Mori, O., Kitamura, S., Ohyama, M., Terashi, A., Kitamoto, T., Katayama, Y.,
Acta Neuropathologica, 98(5), 506-511, 1999 - Pursuit of the origin of the large myelinated tibers of the anterolateral funiculus in the spinal cord in humans in relation to the pathomechanism in amyotrophic lateral sclerosis
Oyanagi, K., Kawakami, E., Morita, T., Takahashi, H.
Acta Neuropathologica, 98(6), 635-640, 1999 - Amyotrophic lateral sclerosis: increased hyaluronic acid in the media of the basilar artery
Oyanagi, K., Nagao, K., Ono, S.,
J Neurol Sci, 167(2), 112-116, 1999
Books and other publications
- Magnesium in the Central Nervous System
Oyanagi K, Hashimoto T, Magnesium in Parkinson's disease: an update in clinical and basic aspects
University of Adelaide Press, 229-236 2011Neurodegeneration the molecular pathology of dementia and movement disorders
Kiyomitsu Oyanagi, Tomoyo Hashimoto, Mineo Yamazaki, Parkinsonism-Dementia Complex of Guam
Wiley-Blackwell, 171-178 2011
ISBN:10.1002/9781444341256.ch18Affiliated academic society
