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MAKABE HIDEFUMI

Academic OrganizationAcademic Assembly School of Science and Technology Institute of AgricultureTEL
Education and Research OrganizationInterdisciplinary Cluster for Cutting Edge Research Institute for Biomedical SciencesFAX
PositionProfessorMail Address
AddressWeb site

Modified:07/19/2021

Profile

Assigned Class
Graduate School of Science and Technology
Faculty of Agriculture Department of Agricultural and Life Sciences Division of Bioscience and Biotechnology
Research Field
Bioorganic chemistry
Current Subject
Synthetic Studies on Natural Products
Keywords:Asymmetric Synthesis Total Synthesis , 1992-2004
Academic Background
Graduate School
Tohoku University , (Graduate School, Division of Agriculture) , 1997

College
Tohoku University , (Faculty of Agriculture) , 1992

Degree
Doctor of Agriculture , Tohoku University
Research Career
Research Career
2014-
2014-

Research

Books, Articles, etc.
Books
The Biological Activities and Synthesis of 2,6-Disubstituted Piperidinols, Frontiers in Natural Product Chemistry 3 , 182-206
2017(Jun.)
Author:Hattori, Y.; Makabe, H.*


Studies on prodelphinidins: isolation, synthesis, and their biological activities, Studies in Natural Products Chemistry, Atta-Ur-Rahman Eds 48 , 323-346
ELSEVIER SCIENCE PUBLISHERS - AMSTERDAM 2016(Jun.)
Author:Makabe, H.*


Recent progress of the synthesis of 2,6-disubstituted hydroxypiperidine alkaloids, Studies in Natural Products Chemistry, Atta-Ur-Rahman Eds 42 , 353-371
ELSEVIER SCIENCE PUBLISHERS - AMSTERDAM 2014
Author:Makabe, H.


(-)-Epicatechin 3-(3”-O-methylgallate) and (+)-catechin 3-(3”-O-methylgallate), and Their anti-inflammatory activity, Tea in Health and Disease Prevention, Academic Press , 1215-1222
Elsevier, Victor R. Preedy Eds. 2012
Author:Makabe, H.


みすずかる信濃の健康志向食品、9章昆虫食の時代がやってくる!, 158-168頁
郷土出版社 2003(Sep.)
Author:信大大学院機能性食料開発学専攻編


Palladium-Catalyzed Hydrometallation, Handbook of Organopalladium Chemistry, VII.4, 2789-2823頁
Wiley-VCH 2002(Jul.)
Author:Makabe, H.; Negishi, E.*


Reactions of Acylpalladium Derivativeswith Enolates and Related Amphiliphilic Reactions, Handbook of Organopalladium Chemistry, VI.2.3, 2455-2471頁
Wiley-VCH 2002(Jul.)
Author:Negishi, E.*; Makabe, H.


Articles
Synthesis of (+)-Muconin via Diastereoselective Oxypalladation
J. Org. Chem.,86:4859-4866. 2021(Mar.)
Author:Sugimoto, M.; Nosho, S.; Hikosaka, G.; Hattori, Y.; Umezawa, K.; Kawamura, A.; Makabe, H.*


Synthesis of (+)-solenopsin via Pd-catalyzed N-Alkylation and Cyclization
Biosci. Biotecnol. Biochem.,85:223-227. 2021(Feb.)
Author:Suzuki, K.; Hattori, Y.; Kawamura, A.; Makabe, H.*


The suppression of IL-17 production from T cells by gallate-type procyanidin is mediated by selectively inhibiting cytokine production from dendritic cells
Biomedicine & Pharmacotherapy,137:111346. 2021(Feb.)
Author:Endo, K.; Sawa, T.; Matsui, R.; Asami, T.; Tanaka, Y.; Makabe, H.; Tanaka, S.*


Procyanidin B2 gallate regulates TNF-α production from T cells through inhibiting glycolytic activity via mTOR-HIF-1 pathway
Biochem. Pharm.,177:113952 2020(Jun.)
Author:Endo, K.; Matsui, R.; Sugiyama. M.; Asami, T.; Inaba, C.; Kobayashi, S.; Makabe, H.; Tanaka, S.*


Identification and characterization of oligomeric proanthocyanidins with significant anti-cancer activity in adzuki beans (Vigna angularis)
Heliyon,5:e02610 2019(Oct. 24)
Author:Kawahara, S.; Ishihara, C.; Matsumoto, K.; Senga, S.; Kawaguchi, K.; Yamamoto, A.; Suwannachot, J.; Hamauzu, Y.; Makabe, H.*; Fujii, H.*


Synthesis of (+)-goniopypyrone and (+)-goniotriol using Pd-catalyzed carbonylation
Tetrahedron Lett.,60:151039 2019(Sep.)
Author:Miyazawa, Y.; Oda-Tanaka, A.; Makabe, H.*


Isolation and characterization of a novel oligomeric proanthocyanidin with significant anti-cancer activities from grape stems (Vitis vinifera)
Scientific Reports,9:12046-12053 2019(Aug.)
Author:Kawahara, S.; Toda, K.; Matsumoto, K.; Ishihara, C.; Nonobe, S.; Matsunaga, C.; Gomi, K. Y.; Senga, S.; Kawaguchi, K.; Yamamoto, A.; Suwannachot, J.; Noda, R.; Kobayashi, S.; Hamauzu, Y.; Makabe, H.*; Fujii, H.*


Adzuki bean (Vigna angularis) extract reduces amyloid-β aggregation and corrects cognitive impairment in Drosophila models of Alzheimer’s disease
Nutrition Research and Practice,13:64-69 2019(Feb.)
Author:Miyazaki, H.; Okamoto, Y.; Watanabe, T.; Katayama, S.; Kawahara, S.; Makabe, H.; Fujii, H.; Yonekura, S.*


Synthesis of (+)-altholactone, (+)-7-epi-altholactone, (-)-etharvensin, and (-)-almuheptolide-A using Pd-catalyzed carbonylation
Tetrahedron Lett.,59:4024-4027 2018(Nov.)
Author:Miyazawa, Y.; Hattori, Y.; Makabe, H.*


Synthesis of epigallocatechin trimer, (epigallocatechin)2-epicatechin, and (epigallocatechin)2-catechin via a Lewis acid mediated one-pot condensation and their antitumor activities in prostate cancer cells
Tetrahedron,74:3534-3542 2018(Jul.)
Author:Ichikawa,M.; Yamamoto,S.; Ishihara,C.; Nonobe, S.; Hattori, Y.; Umezawa, K.; Fujii, H*.;Makabe, H.*


Kale supplementation up-regulates HSP70 and suppresses cognitivedecline in a mouse model of accelerated senescence
Journal of Functional Foods,44:292-298 2018(May)
Author:Kushimoto, S.; Uchibori, Y.; Yanai, S.; Suto, Y.; Kobayashi, H.; Makabe, H.; Nakamura, S.; Katayama, S.*


An asymmetric synthesis of (+)-monomorine I
Tetrahedron: Asymmetry,28:1582-1586 2017(Nov.)
Author:Asai, M.; Takemoto, Y.; Deguchi, A.; Hattori, Y.; Makabe, H.*


Epicatechin oligomers longer than trimers have anti-cancer activities, but not the catechin counterparts
Scientific Reports,7:7791 2017(Aug. 10)
Author:Takanashi, K.; Suda, M.; Matsumoto, K.; Ishihara, C.; Toda, K,; Kawaguchi, K.; Senga, S.; Kobayashi, N.; Ichikawa, M.; Katoh, M.; Hattori, Y.; Kawahara, S. –i.; Umezawa, K.; Fujii, H*.; Makabe, H.*


Synthesis of Isocoumarin Compounds, 8-Hydroxy-6-methoxy-3-pentyl-1H-isochromen-1-one and Fusariumin Analog Using Palladium-catalyzed Carbonylation Trapping with O-Enolate
Heterocycles,94(8):1542-1553 2017(Aug.)
Author:Asai, M.; Hattori, Y.; Makabe, H.*


Synthesis of (-)-isosolenopsin using Diasereoselective Aminopalladation
Heterocycles,94(2):286-296 2017(Feb.)
Author:Takemoto, Y.; Hattori, Y.; Makabe, H*


Procyanidin B2 Gallates Inhibit IFN-γ and IL-17 Production in T cells by Suppressing T-bet and RORγt Expression
International Immunopharmacology,44:87-96 2017(Jan.)
Author:Tanaka, S.*; Furuya, K,;Yamamoto, K.; K. Yamada, K.; Ichikawa, M.; Suda, M.; Makabe, H.


Synthesis of Prodelphinidin Trimer Isolated from Cistus albidus and Its Growth Inhibitory Activity Against Human Prostate Cancer Cell Lines
Heterocycles,92(10):1822-1831 2016(Oct.)
Author:Mori, M.; Matsumoto, K.; Ishihara, C.; Kawaguchi, K.; Kawahara, S. -i.; Hattori, Y.; Fujii, H.;* Makabe, H.*


Synthesis of legioliulin, a fluorescent isocoumarin compound, isolated from Legionella dumoffii using cyclic acylpalladation and Heck reaction
Tetrahedron Lett.,57:3942-3944. 2016(Aug.)
Author:Asai, M.; Hattori, Y.; Makabe, H*


Concise Synthesis of Cinnamtannin A2 from Dimeric Epicatechin Electrophile and Nucleophile Prepared by Zn(OTf)2 Mediated Self-Condensation
Synthesis,48:1525-1532 2016(May)
Author:Ichikawa, M.; Takanashi, K.; Suda, M.; Hattori, Y.; Kawahara, S.-i.; Fujii, H.; Makabe, H*.


Synthesis of Decytospolide A, B and Their C-3-epimers Using Stereoselective Oxypalladation
Synthesis,48:765-771 2016(Mar.)
Author:Kurogome, Y.; Hattori, Y.; Makabe, H.*


Synthesis of Arecatannin A from Dimeric Epicatechin Electrophile
Nat. Prod. Commun.,10(6):959-962 2015(Jun.)
Author:Suda, M.; Takanashi, K.; Katoh, M.; Matsumoto, K.; Kawaguchi, K.; Kawahara, S. -i.; Fujii, H.; Makabe, H.*


Divergent Synthesis of 2,6-Disubstituted Piperidine Alkaroid, (+)-Spectaline by Palladium-Catalyzed Cyclization
Heterocycles,91(5):959-969 2015(May)
Author:Katsuyama, M.; Furuta, M.;Kobayashi, K.; Teruya, K.; Makabe, H.; Akaji, K.; Hattori, Y.*


Syntheses of a pyrrolidine analog of a tetrahydrofuran containing acetogenin, cis-solamin
Heterocycles,91(3):573-582 2015(Mar.)
Author:Onishi, K.; Sakurai, H.; Kobayashi, K.; Makabe, H.; Teruya, K.; Akaji, K.; Hattori, Y.*


Selective Synthesis of Epicatechin Dimers Using Zn(OTf)2 Mediated Self- Condensation
Synthesis,46(24):3351-3355 2014(Dec. 15)
Author:Suda, M.; Fujii, W.; Takanashi, K.; Hattori, Y.; Makabe, H.*


Synthesis of both enantiomer of akolactone B and (+)-ancepsenolide
Tetrahedron: Asymmetry,25(20-21):1367-1371 2014(Oct. 31)
Author:Hikosaka,G.; Hattori,Y.;Makabe, H*


Synthesis of four diastereomers and structural revision of tetradenolide
Tetrahedron Lett.,55(30):4189-4192 2014(Jul. 23)
Author:Tokuda, M.; Kurogome, Y.; Katoh, R.; Nohara, Y.; Hattori, Y.; Makabe, H.*


Synthesis of (+)-boronolide and (+)-deacetylboronolide using Pd-catalyzed carbonylation and lactonization
Tetrahedron Lett.,55(17):2822-2824 2014(Apr. 23)
Author:Kurogome, Y.; Hattori, Y.; Makabe, H*


Syntheses of prodelphinidin B1, B2 and B4 and their antitumor activities against human PC-3 prostate cancer cell lines
Tetrahedron Lett.,54(52):7188-7192 2013(Dec. 25)
Author:Fujii, W.; Toda, K.; Matsumoto, K.; Kawaguchi, K.; Kawahara, S. -i.; Hattori, Y.; Fujii, H.*; Makabe, H.*


Recent Syntheses of Proanthocyanidin
Heterocycles,87(11):2225-2248 2013(Nov. 01)
Author:Makabe, H.*


Total synthesis of (+)-azimine via diastereoselective aminopalladation
Tetrahedron,69(39):8349-8352 2013(Sep. 30)
Author:Kurogome, Y.; Kogiso, M.; Looi, K. K.; Hattori, Y.; Konno, H.; Hirota, M.; Makabe, H.*


Syntheses of procyanidin B2and B3 gallatederivatives using equimolar condensation mediated by Yb(OTf)3 and their antitumor activities
Bioorg. Med. Chem. Lett.,23(17):4935-4939 2013(Sep. 01)
Author:Suda, M.; Katoh, M.; Toda, K.; Matsumoto, K.; Kawaguchi, K.; Kawahara, S-i.; Hattori, Y.; Fujii, H.*; Makabe, H.*


Stereoselective Aminopalladation and Oxypalladation and Their Application to the Synthesis of Natural Products
Nat. Prod. Commun.,8(7):1005-1010 2013(Jul.)
Author:Makabe, H.


Syntheses of prodelphinidin B3 and C2, and their antitumor activities through cell cycle arrest and caspase-3 activation
Tetrahedron,69(17):3543-3550 2013(Apr. 18)
Author:Fujii, W.; Toda, K.; Kawaguchi, K.; Kawahara, S-i.; Katoh, M.; Hattori, Y.; Fujii,H.*; Makabe, H.*


“Enzymatic synthesis of novel phenol acid rutinosides using rutinase and their antiviral activity in vitro”
J. Agric. Food Chem.,61:9617-9622 2013
Author:Katayama, S.; Ohno, F.; Yamauchi,Y.; Kato, M.; Makabe, H.; Nakamura, S.*


Synthesis of Procyanidin C2 and C1 Using Lewis Acid Mediated Equimolar Condensation
Heterocycles,85(9):2241-2250 2012(Sep.)
Author:Oizumi, Y.; Katoh, M.; Hattori, Y.; Toda, K.; Kawaguchi, K.; Fujii, H.; Makabe, H.*


Synthesis of Procyanidin B1, B2, and B4 and Their Anti-inflammatory Activity
Lett. Org. Chem.,9(4):233-238 2012
Author:Katoh, M.; Oizumi, Y.; Mohri, Y.; Hirota, M.; Makabe, H.*


Efficient Stereoselective Synthesis of Catechin Trimer Derivative Using Silver Lewis Acid Catalyzed Equimolar Condensation
Heterocycles,83(4):739-742 2011
Author:Oizumi, Y.; Mohri, Y.; Hattori, Y.; Makabe,H.*


バイレンシ科アセトゲニン類の合成とミトコンドリアcomplexIに対する阻害活性
有機合成化学協会誌,69(2):159-168 2011
Author:服部恭尚,今野博行,三芳秀人,真壁秀文*


Synthesis of solamin type mono-THF acetogenins using cross-metathesis
Tetrahedron,66(40):7946-7953 2010
Author:Konno, H*.; Makabe, H.; Hattori, Y.; Nosaka,K.; Akaji, K.


Synthesis of Procyanidin B3 and Its Anti-inflammatory Activity. The Effect of 4-Alkoxy Group of Catechin Electrophile in the Yb(OTf)3 Catalyzed Condesation with Catechin Nucleophile
J. Org. Chem.,75(14):4884-4886 2010
Author:Oizumi, Y.; Mohri, Y.; Hirota, M.; Makabe,H.*


Synthesis of Annonacin Isolated from Annona densicoma
Biosci. Biotechnol. Biochem.,74(6):1274-1275 2010
Author:Oasa, M., Hattori, Y., Konno, H., Makabe, H.*


Asymmetric syntheses of daedalin A and quercinol and their tyrosinase inhibitory activity
Bioorg. Med.Chem.Lett.,20(3):1063-1064 2010
Author:Sekimoto, M.; Hattori, Y.; Morimura, K.; Hirota,M.; Makabe, H.*


Heat treatment of Chinese quince polyphenols increases rat plasma levels of protocatechine and vanilic acids
Food Chem.,118(3):757-763 2010
Author:Hamauzu, Y.*; Takedachi, N.; Miyasaka, R.; Makabe, H.


Short Step Synthesis of Resveratrol Derivative from Commercially Available 1,3-Dimethoxybenzene and 4-Vinylanisole
Biosci. Biotechnol. Biochem.,73(11):2547-2548 2009
Author:Iijima, T; Makabe, H.*


A Concise Synthesis of Solamin and cis-Solamin, Mono-THF Acetogenins from Annona muricata
Heterocycles,78(9):2369-2376 2009
Author:Makabe, H.*; Kuwabara, A.; Hattori, Y.; Konno, H.


Daedalin A, a Metabolite of Daedalia dickinsii, Inhibits Melanin Synthesis in an in vitro Human Skin Model
Biosci. Biotechnol. Biochem.,73(3):627-632 2009
Author:Morimura, K.,Hiramatsu, K.; Yamazaki, C., Hattori, Y., Makabe, H., Hirota, M.*


AnEfficient Synthesisof Procyanidins using Equimolar Condensation of Catechin and/or Epicatechin Catalyzed by Ytterbium Triflate
Heterocycles,79(1):549-563 2009
Author:Mohri,Y.; Sagehashi, M.; Yamada, T.; Hattori, Y.; Morimura, K.; Hamauzu, Y.; Kamo, T.; Hirota, M.; Makabe, H.*


Synthesis of (-)-Epicatechin 3-(3"-O-Methylgallate) and (+)-Catechin 3-(3"-O-Methylgallate) and Their Anti-infalammatory Activity
Chem. Biodivers.,6(4):520-526 2009
Author:Iijima, T.; Mohri, Y.; Hattori, Y.; Kashima, A.; Kamo, T.; Hirota, M.; Kiyota, H.; Makabe, H.*


Taxpropellane: A Novel Taxane with an Unprecedented Polycyclic Skeleton from the Needles of Taxus canadensis
Eur. J. Org. Chem.,:5414-5417 2008
Author:Zhang, M. L; Dong, M.; Huo, C. -H.; Li, L. -G.; Sauriol, F.; Shi, Q.-W.*; Gu,Y. -C.; Makabe, H.; Kiyota, H.


Synthesis of pyranicin and its deoxygenated analogues and their inhibitory action with bovine heart mitochondrial complex I
Tetrahedron,64:7695-7703 2008
Author:Furuhata, S.;Hattori, Y.; Okajima, M.; Konno, H.; Abe, M.; Miyoshi, H.; Goto, T.; Makabe, H.*


DynamicFunction of the Spacer Region of Acetogenins in the Inhibition of Bovine Mitochondrial NADH-Ubiquinone Oxidoreductase (Complex I)
Biochemistry,47(23):6257-6263 2008
Author:Abe, M.; Kubo, A.; Yamamoto, S.; Hatoh, Y.; Murai, M.; Hattori, Y.; Makabe, H.; Nishioka, T.; Miyoshi, H.*


Synthesis of Pyranicin and Its Inhibitory Action with Bovine Heart Mitochondrial Complex I
Org. Lett.,10:717-720 2008
Author:Hattori, Y.; Furuhata, S.; Okajima, M.; Konno, H.; Abe, M.; Miyoshi, H.; Goto, T.; Makabe, H.*


Stimulation conditions for spore germination of Agaricus blazei
Mushuroom Science and Biotechnology,16(2):87-92 2008
Author:Mahmud, M. A.; Ohno, S.; Fukuda, M.*; Yamada, A.; Hattori, Y.; Makabe, H.


Total synthesis of cis-solamin A, a mono-tetrahydrofuran acetogenin isolated from Annona muricata
Tetrahedron Lett.,49:782-785 2008
Author:Konno, H.*; Okuno, Y.; Makabe, H.; Nosaka, K.; Onishi, A.; Abe, Y.; Sugimoto, A.; Akaji, K.


Current Topics of Organic and Biological Chemistry of Annonaceous Acetogenins and Their Synthetic Mimics
Current Drug Discovery Technologies,5(3):213-229 2008
Author:Makabe, H.*; Konno, H.; Miyoshi, H.*


A Tyrosinase Inhibitor, Daedalin A, from the Mycelial Culture of Daedalea dickinsi
Biosci. Biotechnol. Biochem.,71:2837-2840 2007
Author:Morimura, K., Yamazaki, C., Hattori, Y., Makabe, H., Kamo, T., Hirota,M.*


Synthesis of Annonaceous Acetogenins from Muricatacin
Biosci. Biotechnol. Biochem.,71:2367-2374 2007
Author:Makabe, H.


An efficient synthesis of procyanidins. Rare earth metal Lewis acid catalyzed equimolar condensation of catechin and epicatechin
TetrahedronLett.,48:5891-5894 2007
Author:Mohri, Y., Sagehashi, M., Yamada, T., Hattori, Y., Morimura, K., Kamo, T., Hirota, M., Makabe, H.*


A refined method for determining the absolute configuration of the 3-hydroxy-3-methylglutaryl group
Tetrahedron: Asymmetry,18:1183-1186 2007
Author:Hattori, Y., Horikawa, K., Makabe, H., Hirai, N., Hirota, M., Kamo, T.*


Total synthesis of miraziridine A and identification of its major reaction site for cathepsin B
Tetrahedron,63:9502-9513 2007
Author:Konno, H.*; Kubo, K.; Makabe, H.; Toshiro,E.; Hinoda, N.; Nosaka, K.; Akaji, K.


Synthesis, determination of the absolute configuration oftonkinelin, and inhibitoryaction with bovine heart mitochondrial complex I
Bioorg. Med. Chem.,15:3026-3031 2007
Author:Hattori, Y., Konno, H., Abe, M., Miyoshi, T. Goto, T., Makabe, H.*


Synthesis of (4R,15R,16R,21S)- and (4R,15S,16S,21S)-rollicosin, squamostolide, and their inhibitory action with bovine heart mitochondrial complex I
BIOORGANIC&MEDICINAL CHEMISTRY,14(9):3119-3130 2006
Author:Makabe, H.*; Kimura, Y; Higuchi, M; Konno, H; Murai, M;Miyoshi, H


Anti-inflammatory sesquiterpenes from Curcuma zedoaria
NATURAL PRODUCT RESEARCH,20(7):680-685 2006
Author:Makabe, H.*; Maru, N; Kuwabara, A; Kamo, T; Hirota, M


Synthesis of murisolin, (15R, 16R, 19R, 20S)-murisolin A, and (15R, 16R, 19S, 20S)-16,19-cis-murisolin and their inhibitory action with bovine heart mitochondrial complex I
CHEMISTRY-AN ASIAN JOURNAL,1(6):894-904 2006
Author:Hattori,Y; Kimura, Y; Moroda, A; Konno, H; Abe, M; Miyoshi, H; Goto, T; Makabe, H.*


Repraesentins D, E and F, New Plant Growth Promoters from Lactarius repraesentaneus
Biosci. Biotechnol. Biochem.,70(6):1502-1505 2006
Author:Kashiwabara, M.; Kamo, T.*; Makabe, H.; Shibata, H.; Hirota, M.


Synthesis and inhibition mechanism ofDelta lac-acetogenins, a novel type of inhibitor of bovine heart mitochondrial complex I
BIOCHEMISTRY,44(2):816-825 2005
Author:Ichimaru, N; Murai, M; Abe, M; Hamada, T; Yamada, Y; Makino, S; Nishioka, T; Makabe, H; Makino, A; Kobayashi, T; Miyoshi, H.*


Synthesisof(4R,15R,16R,21S)- and (4R,15S,16S,21S)-rollicosin
TETRAHEDRON LETTERS,46(27):4671-4675 2005
Author:Makabe, H.*; Higuchi, M; Konno, H; Murai, M; Miyoshi, H


Dynamic function of the alkyl spacer of acetogenins in their inhibitory action with mitochondrial complex I (NADH-ubiquinone oxidoreductase)
BIOCHEMISTRY,44(45):14898-14906 2005
Author:Abe, M; Murai, M; Ichimaru,N; Kenmochi, A; Yoshida, T; Kubo, A; Kimura, Y; Moroda, A;Makabe, H; Nishioka, T; Miyoshi,H.*


Synthesis and mitochondrial complex I inhibition of dihydroxy-cohibin A, non-THF annonaceous acetogenin analogue
Bioorg. Med. Chem. Lett.,14(3):629-632 2004(Jan.)
Author:Konno, H.*; Hiura, N.; Makabe, H.; Abe, M.; Miyoshi, H.


Synthesis of two possible diastereomers of reticulatain-1
Tetrahedron Lett.,45(5):973-977 2004(Jan.)
Author:Makabe, H.*; Miyawaki, A.; Takahashi, R.; Hattori, Y.; Konno, H.; Abe, M.; Miyoshi, H.


Anti-inflammatory cyathane diterpenoids from Sarcodon scabrosus
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY,68(6):1362-1365 2004
Author:Kamo, T.*; Imura, Y; Hagio, T; Makabe, H; Shibata, H; Hirota, M


Total synthesis of cis-solamin and its inhibitory action with bovine heart mitochondrial complex I
TETRAHEDRON,60(47):10651-10657 2004
Author:Makabe, H.*; Hattori, Y; Kimura, Y; Konno, H; Abe, M; Miyoshi, H; Tanaka,A;Oritani, T


Efficient Synthesis of Akolactone A via Pd-Catalyzed Carbonylation
Biosci. Biotechnol. Biochem.,67(12):2658-2660 2003(Dec.)
Author:Makabe, H.*; Okajima, M.; Konno, H.; Kamo, T.; Hirota, M.


Total Synthesis of (-)-Cassine
Org. Lett.,5(1):27-29 2003(Jan.)
Author:Makabe, H.*; Kong, L. K.; Hirota, M.


Structural revision of epoxyrollins A and B, biosynthetic precursors of annonaceous acetogenins
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY,67(6):1438-1441 2003
Author:Konno, H.*; Makabe, H


New plant growth promoters, repraesentins A, B and C, from Lactarius repraesentaneus
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY,67(7):1597-1600 2003
Author:Hirota, M.*; Shimizu, Y; Kamo, T;Makabe, H; Shibata, H.


Myrsinoic acid E, an anti-inflammatory compound from Myrsine seguinii
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY,67(9):2038-2041 2003
Author:Makabe, H.* Miyazaki, S; Kamo, T; Hirota, M


Total Synthesis of cis-Solamin
Org. Lett.,4(7):1083-1085 2002(Apr.)
Author:Makabe, H.*; Hattori, Y.; Tanaka, A.; Oritani, T.


バイレンシ科アセトゲニン類の合成研究
信州大学農学部紀要,37(2):93-99 2001(Mar.)
Keywords:Annonaceous,acetogenins,Annonaceae,Total Synthesis,Antitumor


A Novel Hydrogen Transfer Hydroalumination of Alkenes withTriisobutylaluminum Catalyzed by Pd and Other Late Transition Metal Complexes
Tetrahedron Lett.,42(2):785-787 2001(Jan.)
Author:Gagneur, S.; Makabe, H.; Negishi, E.*


Intermolecular trapping of acylpalladium and related acylmetal derivatives with active C-H compounds
J. Mol. Cat. (A),143:279-286 1999(Jan.)
Author:Negishi, E.*; Liou, S. -Y.; Xu, C.; Shimoyama, I.; Makabe, H.


Hydrogen Transfer Hydrozirconation of Alkenes with i-BuZrCp2Cl Catalyzed by Lewis-Acidic Metal Compounds Containing Al, Zn, Si, Ag, and Pd
Eur. J. Org. Chem.,:969-971 1999
Author:Makabe, H.; Negishi, E.*


Catalytic Generation and Trapping Acylmetals Containing Ni and Cu with Enolates
Tetrahedron,54(2):1095-1106 1998(Jan.)
Author:Negishi, E.*; Makabe, H.; Shimoyama, I.; Wu, G.; Zhang, Y.


Total Synthesis of (+)-4-Deoxygigantecin
Tetrahedron,54:6329-6340 1998
Author:Makabe, H.; Tanaka, A.*; Oritani, T.


Total Synthesis of (+)-4-Deoxygigantecin
Tetrahedron Lett.,38(24):4247-4250 1997(Jun.)
Author:Makabe, H.; Tanaka, A.*; Oritani, T.


Total Synthesis of (8’R)-,and (8’S)-Corrosoline
Heterocycles,43(10):2229-2248 1996(Oct.)
Author:Makabe, H.; Tanimoto, H.; Tanaka, A.*; Oritani, T.


Total Synthesis of (15S, 16R, 19S, 20R, 34S)-Diepomuricanin
Tetrahedron Lett.,37(30):5393-5396 1996(Aug.)
Author:Konno, H.; Makabe, H.; Tanaka, A.*; Oritani, T.


Synthesis of Two Possible Diastereoisomers of the Epoxy Lactone Proposed for an Annonaceous Acetogenins, Epoxyrollin A
Tetrahedron,52(28):9399-9408 1996(Jul.)
Author:Konno, H.; Makabe, H.; Tanaka, A.*; Oritani, T.


Syntehsis of Squamostanal-A
Biosci. Biotechnol. Biochem.,60(3):526-527 1996(Mar.)
Author:Konno, H.; Makabe, H.; Tanaka, A.*; Oritani, T.


Synthesis of Two Possible Diastereoisomers of the Epoxy Lactone Proposed for Epoxyrollin A
Biosci. Biotechnol. Biochem.,59(12):2355-2357 1995(Dec.)
Author:Konno, H.; Makabe, H.; Tanaka, A.*; Oritani, T.


Total Synthesis of Solamin and Reticulatacin
J. Chem. Soc. Perkin Trans. 1,:1975-1981 1994
Author:Makabe, H.; Tanaka, A.*; Oritani, T.


Synthesis of (-)-Muricatacin
Biosci. Biotechnol. Biochem.,57(6):1028-1029 1993(Jun.)
Author:Makabe, H.; Tanaka, A.*; Oritani, T.

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20130801 - 20150731 , 日本学術振興会 , 特別研究員審査会専門委員会書面審査員
20110801 - 20120731 , 日本学術振興会 , 特別研究員審査会専門委員会書面審査員

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2016 - 2016 , Certificate of Outstanding Contribution in Reviewing in Bioorganic & Medicinal Chemistry Letters
2014 - 2014 , Certificate of Outstanding Contribution in Reviewing Tetrahedron (Elsevier)