SHIBA Yuji
Academic Assembly School of Medicine and Health Sciences Institute of Medicine
Interdisciplinary Cluster for Cutting Edge Research Institute for Biomedical Sciences
Professor
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Paper
- Regeneration of Nonhuman Primate Hearts With Human Induced Pluripotent Stem Cell-Derived Cardiac Spheroids.
Hideki Kobayashi; Shugo Tohyama; Hajime Ichimura; Noburo Ohashi; Shuji Chino; Yusuke Soma; Hidenori Tani; Yuki Tanaka; Xiao Yang; Naoko Shiba; Shin Kadota; Kotaro Haga; Taijun Moriwaki; Yuika Morita-Umei; Tomohiko C Umei; Otoya Sekine; Yoshikazu Kishino; Hideaki Kanazawa; Hiroyuki Kawagishi; Mitsuhiko Yamada; Kazumasa Narita; Takafumi Naito; Tatsuichiro Seto; Koichiro Kuwahara; Yuji Shiba; Keiichi Fukuda
Circulation, Apr. 2024
- Efficacy of exon-skipping therapy for DMD cardiomyopathy with mutations in actin binding domain 1.
Naoko Shiba; Xiao Yang; Mitsuto Sato; Shin Kadota; Yota Suzuki; Masahiro Agata; Kohei Nagamine; Masaki Izumi; Yusuke Honda; Tomoya Koganehira; Hideki Kobayashi; Hajime Ichimura; Shinichiro Chuma; Junichi Nakai; Shugo Tohyama; Keiichi Fukuda; Daigo Miyazaki; Akinori Nakamura; Yuji Shiba
Molecular therapy. Nucleic acids, 34, 102060-102060, Dec. 2023 - Mature human induced pluripotent stem cell-derived cardiomyocytes promote angiogenesis through alpha-B crystallin.
Yuki Tanaka; Shin Kadota; Jian Zhao; Hideki Kobayashi; Satomi Okano; Masaki Izumi; Yusuke Honda; Hajime Ichimura; Naoko Shiba; Takeshi Uemura; Yuko Wada; Shinichiro Chuma; Tsutomu Nakada; Shugo Tohyama; Keiichi Fukuda; Mitsuhiko Yamada; Tatsuichiro Seto; Koichiro Kuwahara; Yuji Shiba
Stem cell research & therapy, 14(1), 240-240, Sep. 2023 - Cardiac Regeneration Using Pluripotent Stem Cells and Controlling Immune Responses.
Hajime Ichimura; Shuji Chino; Yuji Shiba
Heart, lung & circulation, 32(7), 836-843, Jul. 2023 - Intracoronary transplantation of pluripotent stem cell-derived cardiomyocytes: Inefficient procedure for cardiac regeneration.
Hideki Kobayashi; Shugo Tohyama; Hideaki Kanazawa; Hajime Ichimura; Shuji Chino; Yuki Tanaka; Yota Suzuki; Jian Zhao; Naoko Shiba; Shin Kadota; Kazumasa Narita; Takafumi Naito; Tatsuichiro Seto; Koichiro Kuwahara; Yuji Shiba; Keiichi Fukuda
Journal of molecular and cellular cardiology, 174, 77-87, Jan. 2023 - Restoring Dystrophin Expression with Duchenne Muscular Dystrophy Exon 45 Skipping in Induced Pluripotent Stem Cell-Derived Cardiomyocytes.
Mitsuto Sato; Naoko Shiba; Daigo Miyazaki; Yuji Shiba; Akinori Nakamura
Methods in molecular biology (Clifton, N.J.), 2587, 141-151, 2023 - Chemical Genetics Reveals a Role of Squalene Synthase in TGFβ Signaling and Cardiomyogenesis.
Yasushi Takemoto; Shin Kadota; Itsunari Minami; Shinya Otsuka; Satoshi Okuda; Masahiro Abo; Louvy Lynn Punzalan; Yan Shen; Yuji Shiba; Motonari Uesugi
Angewandte Chemie (International ed. in English), 60(40), 21824-21831, Sep. 2021 - Transplantation of Pluripotent Stem Cell-Derived Cardiomyocytes into a Myocardial Infarction Model of Cynomolgus Monkey.
Hideki Kobayashi; Hajime Ichimura; Noburou Ohashi; Yuji Shiba
Methods in molecular biology (Clifton, N.J.), 2320, 295-302, 2021 - Pluripotent Stem Cells for Cardiac Regeneration - Current Status, Challenges, and Future Perspectives.
Yuji Shiba
Circulation journal : official journal of the Japanese Circulation Society, 84(12), 2129-2135, Nov. 2020 - Establishment of a heart-on-a-chip microdevice based on human iPS cells for the evaluation of human heart tissue function.
Mosha Abulaiti; Yaxiaer Yalikun; Kozue Murata; Asako Sato; Mustafa M Sami; Yuko Sasaki; Yasue Fujiwara; Kenji Minatoya; Yuji Shiba; Yo Tanaka; Hidetoshi Masumoto
Scientific reports, 10(1), 19201-19201, Nov. 2020 - Heart regeneration using pluripotent stem cells.
Shin Kadota; Yuki Tanaka; Yuji Shiba
Journal of cardiology, 76(5), 459-463, Nov. 2020 - β-Arrestin-Biased AT1 Agonist TRV027 Causes a Neonatal-Specific Sustained Positive Inotropic Effect Without Increasing Heart Rate.
Toshihide Kashihara; Hiroyuki Kawagishi; Tsutomu Nakada; Takuro Numaga-Tomita; Shin Kadota; Elena E Wolf; Cheng-Kun Du; Yuji Shiba; Sachio Morimoto; Mitsuhiko Yamada
JACC. Basic to translational science, 5(11), 1057-1069, Nov. 2020 - beta-Arrestin Biased AT(1) Agonist TRVO27 Causes a Neonatal-Specific Sustained Positive Inotropic Effect Without Increasing Heart Rate
Kashihara, Toshihide; Kawagishi, Hiroyuki; Nakada, Tsutomu; Numaga-Tomita, Takuro; Kadota, Shin; Wolf, Elena E.; Du, Cheng-Kun; Shiba, Yuji; Morimoto, Sachio; Yamada, Mitsuhiko;
JACC-BASIC TO TRANSLATIONAL SCIENCE, 5(11), 1057-1069, Nov. 2020 - Increased predominance of the matured ventricular subtype in embryonic stem cell-derived cardiomyocytes in vivo.
Hajime Ichimura; Shin Kadota; Toshihide Kashihara; Mitsuhiko Yamada; Kuniaki Ito; Hideki Kobayashi; Yuki Tanaka; Naoko Shiba; Shinichiro Chuma; Shugo Tohyama; Tatsuichiro Seto; Kenji Okada; Koichiro Kuwahara; Yuji Shiba
Scientific reports, 10(1), 11883-11883, Jul. 2020 - Circulating re-entrant waves promote maturation of hiPSC-derived cardiomyocytes in self-organized tissue ring.
Junjun Li; Lu Zhang; Leqian Yu; Itsunari Minami; Shigeru Miyagawa; Marcel Hörning; Ji Dong; Jing Qiao; Xiang Qu; Ying Hua; Nanae Fujimoto; Yuji Shiba; Yang Zhao; Fuchou Tang; Yong Chen; Yoshiki Sawa; Chao Tang; Li Liu
Communications biology, 3(1), 122-122, Mar. 2020 - Amelioration of intracellular Ca2+ regulation by exon-45 skipping in Duchenne muscular dystrophy-induced pluripotent stem cell-derived cardiomyocytes.
Mitsuto Sato; Naoko Shiba; Daigo Miyazaki; Yuji Shiba; Yusuke Echigoya; Toshifumi Yokota; Hotake Takizawa; Yoshitsugu Aoki; Shin'ichi Takeda; Akinori Nakamura
Biochemical and biophysical research communications, 520(1), 179-185, Nov. 2019 - Pluripotent Stem Cell-Derived Cardiomyocyte Transplantation for Heart Disease Treatment.
Shin Kadota; Yuji Shiba
Current cardiology reports, 21(8), 73-73, Jun. 2019 - Therapeutic Potential of Pluripotent Stem Cells for Cardiac Repair after Myocardial Infarction.
Satomi Okano; Yuji Shiba
Biological & pharmaceutical bulletin, 42(4), 524-530, 2019 - Cardiac Sodium Channel Disease Modeling Using Patient-Derived Induced Pluripotent Stem Cells.
Shin Kadota; Naoko Shiba; Yuji Shiba
Circulation journal : official journal of the Japanese Circulation Society, 81(12), 1764-1765, Nov. 2017 - Human Pluripotent Stem Cell-Derived Cardiac Tissue-like Constructs for Repairing the Infarcted Myocardium.
Junjun Li; Itsunari Minami; Motoko Shiozaki; Leqian Yu; Shin Yajima; Shigeru Miyagawa; Yuji Shiba; Nobuhiro Morone; Satsuki Fukushima; Momoko Yoshioka; Sisi Li; Jing Qiao; Xin Li; Lin Wang; Hidetoshi Kotera; Norio Nakatsuji; Yoshiki Sawa; Yong Chen; Li Liu
Stem cell reports, 9(5), 1546-1559, Nov. 2017 - Impact of extracellular matrix on engraftment and maturation of pluripotent stem cell-derived cardiomyocytes in a rat myocardial infarct model.
Tatsuki Ogasawara; Satomi Okano; Hajime Ichimura; Shin Kadota; Yuki Tanaka; Itsunari Minami; Motonari Uesugi; Yuko Wada; Naoto Saito; Kenji Okada; Koichiro Kuwahara; Yuji Shiba
Scientific reports, 7(1), 8630-8630, Aug. 2017 - 多能性幹細胞を用いた心筋再生治療
門田 真; 柴 祐司
信州医学雑誌, 65(3), 143-152, 10 Jun. 2017 - Recent Progress Using Pluripotent Stem Cells for Cardiac Regenerative Therapy.
Hajime Ichimura; Yuji Shiba
Circulation journal : official journal of the Japanese Circulation Society, 81(7), 929-935, Jun. 2017 - A Synthetic Hybrid Molecule for the Selective Removal of Human Pluripotent Stem Cells from Cell Mixtures.
Di Mao; Shin Ando; Shin-Ichi Sato; Ying Qin; Nao Hirata; Yousuke Katsuda; Eihachiro Kawase; Ting-Fang Kuo; Itsunari Minami; Yuji Shiba; Kazumitsu Ueda; Norio Nakatsuji; Motonari Uesugi
Angewandte Chemie (International ed. in English), 56(7), 1765-1770, Feb. 2017 - Allogeneic transplantation of iPS cell-derived cardiomyocytes regenerates primate hearts.
Yuji Shiba; Toshihito Gomibuchi; Tatsuichiro Seto; Yuko Wada; Hajime Ichimura; Yuki Tanaka; Tatsuki Ogasawara; Kenji Okada; Naoko Shiba; Kengo Sakamoto; Daisuke Ido; Takashi Shiina; Masamichi Ohkura; Junichi Nakai; Narumi Uno; Yasuhiro Kazuki; Mitsuo Oshimura; Itsunari Minami; Uichi Ikeda
Nature, 538(7625), 388-391, Oct. 2016 - [iPS cells as a source of cardiac regeneration].
Tatsuki Ogasawara; Yuji Shiba
Nihon rinsho. Japanese journal of clinical medicine, 74 Suppl 6, 287-92, Aug. 2016 - Association between estimated glomerular filtration rate and peripheral arterial disease.
Saeko Yamasaki; Atsushi Izawa; Megumi Koshikawa; Tatsuya Saigusa; Soichiro Ebisawa; Takashi Miura; Yuji Shiba; Takeshi Tomita; Yusuke Miyashita; Jun Koyama; Uichi Ikeda
Journal of cardiology, 66(5), 430-4, Nov. 2015 - Differential roles of MMP-9 in early and late stages of dystrophic muscles in a mouse model of Duchenne muscular dystrophy.
Naoko Shiba; Daigo Miyazaki; Takahiro Yoshizawa; Kazuhiro Fukushima; Yuji Shiba; Yuji Inaba; Michihiro Imamura; Shin'ichi Takeda; Kenichi Koike; Akinori Nakamura
Biochimica et biophysica acta, 1852(10 Pt A), 2170-82, Oct. 2015 - [Therapeutic angiogenesis by adipose - derived regenerative cell transplantation for severe peripheral artery disease].
Kazuhiro Kimura; Yuji Shiba; Uichi Ikeda
Nihon rinsho. Japanese journal of clinical medicine, 73 Suppl 5, 529-33, Jun. 2015 - Transplantation of adipose tissue-derived stem cells improves cardiac contractile function and electrical stability in a rat myocardial infarction model.
Milan Gautam; Daiki Fujita; Kazuhiro Kimura; Hinako Ichikawa; Atsushi Izawa; Masamichi Hirose; Toshihide Kashihara; Mitsuhiko Yamada; Masafumi Takahashi; Uichi Ikeda; Yuji Shiba
Journal of molecular and cellular cardiology, 81, 139-49, Apr. 2015 - A young patient with atypical type-B Wolff-Parkinson-White syndrome accompanied by left ventricular dysfunction.
Takahiro Takeuchi; Takeshi Tomita; Hiroki Kasai; Daisuke Kashiwagi; Koji Yoshie; Tomonori Yaguchi; Yasutaka Oguchi; Ayako Kozuka; Milan Gautam; Hirohiko Motoki; Ayako Okada; Yuji Shiba; Kazunori Aizawa; Atsushi Izawa; Yusuke Miyashita; Jun Koyama; Minoru Hongo; Uichi Ikeda
Journal of arrhythmia, 31(1), 50-4, Feb. 2015 - New strategy for the treatment of myocarditis by cell-sheet technology.
Yuji Shiba
Circulation journal : official journal of the Japanese Circulation Society, 79(1), 51-2, 2015 - Low levels of high-density lipoprotein cholesterol predict the presence of coronary artery disease in patients with aortic aneurysms.
Tatsuya Saigusa; Atsushi Izawa; Takashi Miura; Soichiro Ebisawa; Yuji Shiba; Yusuke Miyashita; Takeshi Tomita; Jun Koyama; Daisuke Fukui; Tamaki Takano; Jun Amano; Uichi Ikeda
Angiology, 65(8), 710-5, Sep. 2014 - Electrical Integration of Human Embryonic Stem Cell-Derived Cardiomyocytes in a Guinea Pig Chronic Infarct Model.
Yuji Shiba; Dominic Filice; Sarah Fernandes; Elina Minami; Sarah K Dupras; Benjamin Van Biber; Peter Trinh; Yusuke Hirota; Joseph D Gold; Mohan Viswanathan; Michael A Laflamme
Journal of cardiovascular pharmacology and therapeutics, 19(4), 368-381, Jul. 2014 - Importance of fatty acid compositions in patients with peripheral arterial disease.
Milan Gautam; Atsushi Izawa; Yuji Shiba; Hirohiko Motoki; Takahiro Takeuchi; Ayako Okada; Takeshi Tomita; Yusuke Miyashita; Jun Koyama; Uichi Ikeda
PloS one, 9(9), e107003, 2014 - Presence of diastolic dysfunction in patients with peripheral artery disease.
Saeko Yamasaki; Atsushi Izawa; Yuji Shiba; Takeshi Tomita; Yusuke Miyashita; Jun Koyama; Uichi Ikeda
Angiology, 64(7), 540-3, Oct. 2013 - Prostacyclin: a potential new target for endothelial progenitor cell-mediated angiogenesis.
Yuji Shiba; Uichi Ikeda
Circulation journal : official journal of the Japanese Circulation Society, 77(4), 906-7, 2013 - Crucial role of hyaluronan in neointimal formation after vascular injury.
Yuichiro Kashima; Masafumi Takahashi; Yuji Shiba; Naoki Itano; Atsushi Izawa; Jun Koyama; Jun Nakayama; Shun'ichiro Taniguchi; Koji Kimata; Uichi Ikeda
PloS one, 8(3), e58760, 2013 - Human ES-cell-derived cardiomyocytes electrically couple and suppress arrhythmias in injured hearts.
Yuji Shiba; Sarah Fernandes; Wei-Zhong Zhu; Dominic Filice; Veronica Muskheli; Jonathan Kim; Nathan J Palpant; Jay Gantz; Kara White Moyes; Hans Reinecke; Benjamin Van Biber; Todd Dardas; John L Mignone; Atsushi Izawa; Ramy Hanna; Mohan Viswanathan; Joseph D Gold; Michael I Kotlikoff; Narine Sarvazyan; Matthew W Kay; Charles E Murry; Michael A Laflamme
Nature, 489(7415), 322-5, Sep. 2012 - Creation of human cardiac cell sheets using pluripotent stem cells.
Katsuhisa Matsuura; Masanori Wada; Tatsuya Shimizu; Yuji Haraguchi; Fumiko Sato; Kasumi Sugiyama; Kanako Konishi; Yuji Shiba; Hinako Ichikawa; Aki Tachibana; Uichi Ikeda; Masayuki Yamato; Nobuhisa Hagiwara; Teruo Okano
Biochemical and biophysical research communications, 425(2), 321-7, Aug. 2012 - Targeting N-acetylglucosamine-bearing polymer-coated liposomes to vascular smooth muscle cells.
Mamiko Ise; Hirohiko Ise; Yuji Shiba; Satoshi Kobayashi; Mitsuaki Goto; Masafumi Takahashi; Toshihiro Akaike; Uichi Ikeda
Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs, 14(4), 301-9, Dec. 2011 - Notch signaling regulates the differentiation of bone marrow-derived cells into smooth muscle-like cells during arterial lesion formation.
Hiroshi Doi; Tatsuya Iso; Yuji Shiba; Hiroko Sato; Miki Yamazaki; Yoshiaki Oyama; Hideo Akiyama; Toru Tanaka; Tomoyuki Tomita; Masashi Arai; Masafumi Takahashi; Uichi Ikeda; Masahiko Kurabayashi
Biochemical and biophysical research communications, 381(4), 654-9, Apr. 2009 - Bone marrow CXCR4 induction by cultivation enhances therapeutic angiogenesis.
Yuji Shiba; Masafumi Takahashi; Takeki Hata; Hideki Murayama; Hajime Morimoto; Hirohiko Ise; Takashi Nagasawa; Uichi Ikeda
Cardiovascular research, 81(1), 169-77, Jan. 2009 - Cardiac applications for human pluripotent stem cells.
Yuji Shiba; Kip D Hauch; Michael A Laflamme
Current pharmaceutical design, 15(24), 2791-806, 2009 - Deficiency of tumour necrosis factor-alpha and interferon-gamma in bone marrow cells synergistically inhibits neointimal formation following vascular injury.
Hideki Murayama; Masafumi Takahashi; Masaya Takamoto; Yuji Shiba; Hirohiko Ise; Jun Koyama; Yoh-Ichi Tagawa; Yoichiro Iwakura; Uichi Ikeda
Cardiovascular research, 80(2), 175-80, Nov. 2008 - Critical role of bone marrow apoptosis-associated speck-like protein, an inflammasome adaptor molecule, in neointimal formation after vascular injury in mice.
Noriyuki Yajima; Masafumi Takahashi; Hajime Morimoto; Yuji Shiba; Yasuko Takahashi; Junya Masumoto; Hirohiko Ise; Junji Sagara; Jun Nakayama; Shun'ichiro Taniguchi; Uichi Ikeda
Circulation, 117(24), 3079-87, Jun. 2008 - Critical role of bone marrow-derived ASC, an inflammasome adaptor molecule, in neointimal formation after vascular injury in mice.
Yajima N, Takahashi M, Morimoto H, Shiba Y, Takahashi Y, Masumoto J, Ise H, J Sagara, Nakayama J, Taniguchi S, Ikeda U.
Circulation, 117, 3079-3087, 2008 - Models for the study of angiogenesis.
Yuji Shiba; Masafumi Takahashi; Uichi Ikeda
Current pharmaceutical design, 14(4), 371-7, 2008 - Bone marrow-derived CXCR4+ cells mobilized by macrophage colony-stimulating factor participate in the reduction of infarct area and improvement of cardiac remodeling after myocardial infarction in mice.
Hajime Morimoto; Masafumi Takahashi; Yuji Shiba; Atsushi Izawa; Hirohiko Ise; Minoru Hongo; Kiyohiko Hatake; Kazuo Motoyoshi; Uichi Ikeda
The American journal of pathology, 171(3), 755-66, Sep. 2007 - M-CSF accelerates neointimal formation in the early phase after vascular injury in mice: the critical role of the SDF-1-CXCR4 system.
Yuji Shiba; Masafumi Takahashi; Toru Yoshioka; Noriyuki Yajima; Hajime Morimoto; Atsushi Izawa; Hirohiko Ise; Kiyohiko Hatake; Kazuo Motoyoshi; Uichi Ikeda
Arteriosclerosis, thrombosis, and vascular biology, 27(2), 283-9, Feb. 2007 - Granulocyte colony-stimulating factor (G-CSF) accelerates reendothelialization and reduces neointimal formation after vascular injury in mice.
Toru Yoshioka; Masafumi Takahashi; Yuji Shiba; Chihiro Suzuki; Hajime Morimoto; Atsushi Izawa; Hirohiko Ise; Uichi Ikeda
Cardiovascular research, 70(1), 61-9, Apr. 2006 - [Post-myocardial infarction ventricular aneurysm and intractable ventricular tachycardia supported by left ventricular assist device: a case report].
Katsuhito Ueno; Toshio Konishi; Mutsumu Fukata; Kazuhiro Okura; Hiroshi Furukawa; Yuji Shiba; Kazuhiko Yumoto; Toshiyuki Tamaki; Akihiko Nogami; Ken-ichi Kato
Journal of cardiology, 43(5), 231-5, May 2004 - Percutaneous cardiopulmonary support aids resuscitation from sustained ventricular tachycardia.
Atsushi Izawa; Osamu Kinoshita; Yuji Shiba; Wataru Takahashi; Shin-Ichiro Uchikawa; Hiroshi Imamura; Mafumi Owa; Keishi Kubo
Circulation journal : official journal of the Japanese Circulation Society, 67(12), 1061-3, Dec. 2003
MISC
- 幹細胞由来心筋細胞移植による不整脈抑制作用
柴 祐司
週刊医学のあゆみ, 248(2), 161-162, 2014 - Bone marrow-derived CXCR4(+) cells mobilized by macrophage colony-stimulating factor participate in the prevention of cardiac dysfunction after myocardial infarction in mice
Hajime Morimoto; Masafumi Takahashi; Yuji Shiba; Hirohiko Ise; Atsushi Lzawa; Minoru Hongo; Kiyohiko Hatake; Kazuo Motoyoshi; Uichi Ikeda
CIRCULATION, 114(18), 171 - 171, Oct. 2006, Not invited
Books and other publications
- 循環器ジャーナル 68 3
門田 真; 柴 祐司, バイオペースメーカー
医学書院, 422-427 2020心不全に対する再生医療の現状 eLetter 2019年 夏号
柴 祐司
日本心不全学会, 4-5 2019日本臨牀 75 増刊号4号
柴 祐司; 池田宇一, 皮下脂肪由来間葉系前句細胞
日本臨牀社, 256-260 2017化学工業 68 5
岡野怜己; 柴 祐司, 多能性幹細胞を用いた心筋再生治療の開発
小峰工業出版, 8/12 2017日本臨牀増刊号 74 6
小笠原達樹、柴 祐司, 最新冠動脈疾患学（下）
日本臨牀社, 287-292 20 Aug. 2016幹細胞を用いた心筋再生 14 2
柴 祐司, 循環器疾患における再生医療の展望
循環plus, 10-12 2013心筋細胞移植と不整脈 3 9
柴 祐司, 特集循環器再生医療の現状と展望
月刊循環器, 77-84 2013Research Themes
- 心筋再生を実用化するための免疫制御法の開発
科学研究費助成事業, 日本学術振興会, 基盤研究(B)
信州大学
01 Apr. 2024 - 31 Mar. 2028 - 移植免疫の理解に基づく新たな心筋再生治療の開発
科学研究費助成事業, 日本学術振興会, 基盤研究(B)
信州大学
01 Apr. 2024 - 31 Mar. 2025 - 自己細胞を用いた心臓再生への挑戦
科学研究費助成事業, 日本学術振興会, 挑戦的研究(萌芽)
信州大学
30 Jun. 2022 - 31 Mar. 2024 - 移植免疫の理解に基づく新たな心筋再生治療の開発
科学研究費助成事業, 日本学術振興会, 基盤研究(B)
信州大学
01 Apr. 2021 - 31 Mar. 2025 - 新しい心筋補填材料の開発～iPS細胞由来心筋細胞を用いたバイオシートの検討
科学研究費助成事業, 日本学術振興会, 基盤研究(C)
信州大学
01 Apr. 2021 - 31 Mar. 2024 - Development of a new myocardial regeneration therapy using human iPS-derived cardiomyocytes for severe heart failure
Grants-in-Aid for Scientific Research, Japan Society for the Promotion of Science, Grant-in-Aid for Scientific Research (C)
Keio University
01 Apr. 2020 - 31 Mar. 2023 - Evaluation of Post-Transplant Arrhythmia in Human iPSC-Derived Purified Ventricular Cardiomyocytes
Grants-in-Aid for Scientific Research, Japan Society for the Promotion of Science, Grant-in-Aid for Challenging Research (Exploratory)
Keio University
28 Jun. 2019 - 31 Mar. 2021 - Exploration of Self-Assembling Bioactive Small Molecules
Grants-in-Aid for Scientific Research, Japan Society for the Promotion of Science, Grant-in-Aid for Scientific Research (A)
Kyoto University
01 Apr. 2019 - 31 Mar. 2022 - iPS cells for cardiac electrical regeneration
Grants-in-Aid for Scientific Research, Japan Society for the Promotion of Science, Grant-in-Aid for Challenging Research (Exploratory)
Shinshu University
29 Jun. 2018 - 31 Mar. 2020 - Development of DMD exon 3-9 skipping therapy using iPSc
Grants-in-Aid for Scientific Research, Japan Society for the Promotion of Science, Grant-in-Aid for Scientific Research (B)
Shinshu University
01 Apr. 2018 - 31 Mar. 2021 - Development of a method of functional integration between host and graft on the transplantation therapy of human iPS cell-derived cardiac tissues
Grants-in-Aid for Scientific Research, Japan Society for the Promotion of Science, Grant-in-Aid for Scientific Research (B)
Kyoto University
01 Apr. 2018 - 31 Mar. 2021 - Research on pathogenesis and development of therapies for cardiac failure using dystrophin-deficient-cardiomyocytes derived from DMD patients
Grants-in-Aid for Scientific Research, Japan Society for the Promotion of Science, Grant-in-Aid for Scientific Research (C)
Shinshu University
01 Apr. 2018 - 31 Mar. 2021 - Transplantation study of iPS cell-derived cardiomyocytes in non-human primates
Grants-in-Aid for Scientific Research, Japan Society for the Promotion of Science, Grant-in-Aid for Scientific Research (B)
Shinshu University
01 Apr. 2017 - 31 Mar. 2021 - 安全・配向・成熟心筋移植片の開発
科学研究費助成事業, 日本学術振興会, 基盤研究(B)
京都大学
01 Apr. 2015 - 31 Mar. 2018 - Exon 45 skipping theraphy using iPS cells deleted exons 46-55 in the DMD gene
Grants-in-Aid for Scientific Research, Japan Society for the Promotion of Science, Grant-in-Aid for Scientific Research (B)
Shinshu University
01 Apr. 2015 - 31 Mar. 2018 - MHC-matched allogeneic transplantation of iPS cell-derived cardiomyocytes
Grants-in-Aid for Scientific Research, Japan Society for the Promotion of Science, Grant-in-Aid for Scientific Research (B)
Shinshu University
01 Apr. 2014 - 31 Mar. 2017 - Therapeutic angiogenesis using adipose-derived regenerative cell
Grants-in-Aid for Scientific Research, Japan Society for the Promotion of Science, Grant-in-Aid for Scientific Research (C)
Shinshu University
01 Apr. 2014 - 31 Mar. 2017 - Multifaceted profiling of pluripotent stem cells applied in regenerative medicine
Grants-in-Aid for Scientific Research, Japan Society for the Promotion of Science, Grant-in-Aid for Scientific Research (A)
Shinshu University
01 Apr. 2012 - 31 Mar. 2015 - Novel 3D-culture System for iPS Cell-Derived Cardiomyocytes for Cardiac Repair
Grants-in-Aid for Scientific Research, Japan Society for the Promotion of Science, Grant-in-Aid for Young Scientists (B)
Shinshu University
01 Apr. 2012 - 31 Mar. 2014
