Shinshu University HOMEJAPANESEAccess / Campus Map

Shinshu University Researcher DirectoryShinshu University Researcher Directory

Search by Researcher / Research Field
Search by Category

SHIBA Yuji

Academic OrganizationAcademic Assembly School of Medicine and Health Sciences Institute of MedicineTEL
Education and Research OrganizationInterdisciplinary Cluster for Cutting Edge Research, Institute for Biomedical Sciences , Department of Biotechnology and Biomedical EngineeringFAX
PositionProfessorMail Address
Address3-1-1, Asahi, Matsumoto City 390-8621Web site

Profile

Research Field
Cardiology, Stem cell biology
Academic Background
Graduate School
2007

College
1998
Awards
2017
2013 , Cardiovascular Regeneration Medical Science Award

Research

Books, Articles, etc.
Books
最新冠動脈疾患学(下)
日本臨牀社 , 日本臨牀増刊号 , 74(6):287-292 2016(Aug. 20)
Author:小笠原達樹、柴 祐司


心臓病に対する再生医療の現状と課題
The Shinshu Medical Society , 信州医学雑誌 , 63(3):173-175 2015
Author:柴 祐司;


循環器疾患における再生医療の展望
循環plus , 幹細胞を用いた心筋再生 , 14(2):10-12 2013
Author:柴 祐司


特集循環器再生医療の現状と展望
月刊循環器 , 心筋細胞移植と不整脈 , 3(9):77-84 2013
Author:柴 祐司


虚血性心疾患に対する細胞治療・遺伝子治療 (特集/我が国の虚血性心臓病 心筋梗塞と狭心症の診療の進歩) -- (先進医療の開発)
大道学館出版部 , 臨牀と研究 , 84(1):67-72 2007(Jan.)
Author:池田 宇一; 柴 祐司; 高橋 将文;


肺結核で発症したAcquired immunodeficiency syndrome (AIDS)の1例
信州医学会 , 信州医学雑誌 , 48(1):21-25 2000(Feb. 10)
Author:柴 祐司; 小泉 知展; 山本 洋; 蜂谷 勤; 高師 修治; 久保 惠嗣; 本田 孝行; 五味 英一; 小山 関哉;
Abstract:A 57-year-old Japanese male was admitted to our hospital because of high fever and productive cough. The chest radiograph and computed tomography showed consolidation in the right lower lung field and hilar and mediastinal lymphadenopathy. Mycobacterium tuberculosis was positive in his sputum specimen and pulmonary tuberculosis (TB)was diagnosed.Human immunodeficiency virus (HIV)antibody was tested for, because of rapid progression and the radiographic appearance.HIV antibody was positive.He was successfully treated with 3TC,AZT, and protease inhibitor in addition to anti-TB drugs. We have to take the possibility of pulmonary tuberculosis and HIV infection into consideration when rapid progression and an unusual radiographic appearance are observed on the chest radiograph.
Keywords:後天性免疫不全症候群; 肺結核;


Articles
Pluripotent Stem Cell-Derived Cardiomyocyte Transplantation for Heart Disease Treatment
CURRENT CARDIOLOGY REPORTS,21(8):- 2019(Aug.)
Author:Kadota, Shin; Shiba, Yuji;


Therapeutic Potential of Pluripotent Stem Cells for Cardiac Repair after Myocardial Infarction
BIOLOGICAL & PHARMACEUTICAL BULLETIN,42(4):524-530 2019(Apr.)
Author:Okano, Satomi; Shiba, Yuji;


Cardiac Sodium Channel Disease Modeling Using Patient-Derived Induced Pluripotent Stem Cells
CIRCULATION JOURNAL,81(12):1764-1765 2017(Dec.)
Author:Kadota, Shin; Shiba, Naoko; Shiba, Yuji;


Recent Progress Using Pluripotent Stem Cells for Cardiac Regenerative Therapy
CIRCULATION JOURNAL,81(7):929-935 2017(Jul.)
Author:Ichimura, Hajime; Shiba, Yuji;


多能性幹細胞を用いた心筋再生治療
信州医学雑誌,65(3):143-152 2017(Jun. 10)
Author:門田 真; 柴 祐司


多能性幹細胞を用いた心筋再生治療の開発 (特集 革新的バイオ医療と化学)
化學工業,68(5):324-328 2017(May)
Author:岡野 怜己; 柴 祐司;


JAPANESE AUTHOR iPS細胞を用いた新アプローチで心機能改善
Natureダイジェスト,14(1):17-19 2017(Jan.)
Author:柴 祐司;


Impact of extracellular matrix on engraftment and maturation of pluripotent stem cell-derived cardiomyocytes in a rat myocardial infarct model
SCIENTIFIC REPORTS,7:- 2017
Author:Ogasawara, Tatsuki; Okano, Satomi; Ichimura, Hajime; Kadota, Shin; Tanaka, Yuki; Minami, Itsunari; Uesugi, Motonari; Wada, Yuko; Saito, Naoto; Okada, Kenji; Kuwahara, Koichiro; Shiba, Yuji;


Human Pluripotent Stem Cell-Derived Cardiac Tissue-like Constructs for Repairing the Infarcted Myocardium
STEM CELL REPORTS,9(5):1546-1559 2017
Author:Li, Junjun; Minami, Itsunari; Shiozaki, Motoko; Yu, Leqian; Yajima, Shin; Miyagawa, Shigeru; Shiba, Yuji; Morone, Nobuhiro; Fukushima, Satsuki; Yoshioka, Momoko; Li, Sisi; Qiao, Jing; Li, Xin; Wang, Lin; Kotera, Hidetoshi; Nakatsuji, Norio; Sawa, Yoshiki; Chen, Yong; Liu, Li;


A Synthetic Hybrid Molecule for the Selective Removal of Human Pluripotent Stem Cells from Cell Mixtures
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION,56(7):1765-1770 2017
Author:Mao, Di; Ando, Shin; Sato, Shin-ichi; Qin, Ying; Hirata, Nao; Katsuda, Yousuke; Kawase, Eihachiro; Kuo, Ting-Fang; Minami, Itsunari; Shiba, Yuji; Ueda, Kazumitsu; Nakatsuji, Norio; Uesugi, Motonari;


Allogeneic transplantation of iPS cell-derived cardiomyocytes regenerates primate hearts
NATURE,538(7625):388-+ 2016
Author:Shiba, Yuji; Gomibuchi, Toshihito; Seto, Tatsuichiro; Wada, Yuko; Ichimura, Hajime; Tanaka, Yuki; Ogasawara, Tatsuki; Okada, Kenji; Shiba, Naoko; Sakamoto, Kengo; Ido, Daisuke; Shiina, Takashi; Ohkura, Masamichi; Nakai, Junichi; Uno, Narumi; Kazuki, Yasuhiro; Oshimura, Mitsuo; Minami, Itsunari; Ikeda, Uichi;


Differential roles of MMP-9 in early and late stages of dystrophic muscles in a mouse model of Duchenne muscular dystrophy
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE,1852(10):2170-2182 2015(Oct.)
Author:Shiba, Naoko; Miyazaki, Daigo; Yoshizawa, Takahiro; Fukushima, Kazuhiro; Shiba, Yuji; Inaba, Yuji; Imamura, Michihiro; Takeda, Shin'ichi; Koike, Kenichi; Nakamura, Akinori;


Transplantation of adipose tissue-derived stem cells improves cardiac contractile function and electrical stability in a rat myocardial infarction model
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY,81:139-149 2015(Apr.)
Author:Gautam, Milan; Fujita, Daiki; Kimura, Kazuhiro; Ichikawa, Hinako; Izawa, Atsushi; Hirose, Masamichi; Kashihara, Toshihide; Yamada, Mitsuhiko; Takahashi, Masafumi; Ikeda, Uichi; Shiba, Yuji;


New Strategy for the Treatment of Myocarditis by Cell-Sheet Technology
CIRCULATION JOURNAL,79(1):51-52 2015(Jan.)
Author:Shiba, Yuji;


Association between estimated glomerular filtration rate and peripheral arterial disease
JOURNAL OF CARDIOLOGY,66(5-6):430-434 2015
Author:Yamasaki, Saeko; Izawa, Atsushi; Koshikawa, Megumi; Saigusa, Tatsuya; Ebisawa, Soichiro; Miura, Takashi; Shiba, Yuji; Tomita, Takeshi; Miyashita, Yusuke; Koyama, Jun; Ikeda, Uichi;


Electrical Integration of Human Embryonic Stem Cell-Derived Cardiomyocytes in a Guinea Pig Chronic Infarct Model.
J Cardiovasc Pharmacol Ther,19(4):368-381 2014
Author:Shiba Y, Filice D, Fernandes S, Minami E, Dupras SK, Biber BV, Trinh P, Hirota Y, Gold JD.


Importance of fatty acid compositions in patients with peripheral arterial disease.
PLoS One,9(9):e107003 2014
Author:Gautam M, Izawa A, Shiba Y, Motoki H, Takeuchi T, Okada A, Tomita T, Miyashita Y, Koyama J, Ikeda U.


Low levels of high-density lipoprotein cholesterol predict the presence of coronary artery disease in patients with aortic aneurysms.
Angiology,65(8):710-715 2014
Author:Saigusa T, Izawa A, Miura T, Ebisawa S, Shiba Y, Miyashita Y, Tomita T, Koyama J, Fukui D, Takano T, Amano J, Ikeda U.


Crucial role of hyaluronan in neointimal formation after vascular injury.
PLoS One,8(3):e58760 2013
Author:Kashima Y, Takahashi M, Shiba Y, Itano N, Izawa A, Koyama J, Nakayama J, Taniguchi S, Kimata K, Ikeda U.


Presence of diastolic dysfunction in patients with peripheral artery disease.
Angiology,64(7):540-543 2013
Author:Yamasaki S, Izawa A, Shiba Y, Tomita T, Miyashita Y, Koyama J, Ikeda U.


Prostacyclin - a potential new target for endothelial progenitor cell-mediated angiogenesis -.
Circ J,77(4):906-907 2013
Author:Shiba Y, Ikeda U.


hESC-derived cardiomyocytes electrically couple and suppress arrhythmias in injured hearts
Nature,489(7415):322-325 2012
Author:Shiba Y, Fernandes S, Zhu WZ, Filice D, Muskheli V, Kim J, Palpant NJ, Gantz J, Moyes KW, Reinecke H, Van Biber B, Dardas T, Mignone JL, Izawa A, Hanna R, Viswanathan M, Gold JD, Kotlikoff MI, Sarvazyan N, Kay MW, Murry CE, Laflamme MA


Creation of human cardiac cell sheets using pluripotent stem cells
Biochem Biophys Res Commun,425(2):321-327 2012
Author:Matsuura K, Wada M, Shimizu T, Haraguchi Y, Sato F, Sugiyama K, Konishi K, Shiba Y, Ichikawa H, Tachibana A, Ikeda U, Yamato M, Hagiwara N, Okano T


Targeting N-acetylglucosamine-bearing polymer-coated liposomes to vascular smooth muscle cells.
J Artif Organs,14:301-309 2011
Author:Ise M, Ise H, Shiba Y, Kobayashi S, Goto M, Takahashi M, Akaike T, Ikeda U.


Notch signaling regulates the differentiation of bone marrow-derived cells into smooth muscle-like cells during arterial lesion formation
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS,381(4):654-659 2009
Author:Doi, Hiroshi; Iso, Tatsuya; Shiba, Yuji; Sato, Hiroko; Yamazaki, Miki; Oyama, Yoshiaki; Akiyama, Hideo; Tanaka, Toru; Tomita, Tomoyuki; Arai, Masashi; Takahashi, Masafumi; Ikeda, Uichi; Kurabayashi, Masahiko;


Bone marrow CXCR4 induction by cultivation enhances therapeutic angiogenesis.
Cardiovasc Res,81:169-177 2009
Author:Shiba Y, Takahashi M, Hata T, Murayama H, Morimoto H, Ise H, Nagasawa T, Ikeda U.


Models for the study of angiogenesis.
Curr Pharm Design,14:371-377 2008
Author:Shiba Y, Takahashi M, Ikeda U.


Critical role of bone marrow-derived ASC, an inflammasome adaptor molecule, in neointimal formation after vascular injury in mice.
Circulation,117:3079-3087 2008
Author:Yajima N, Takahashi M, Morimoto H, Shiba Y, Takahashi Y, Masumoto J, Ise H, J Sagara, Nakayama J, Taniguchi S, Ikeda U.


Deficiency of tumor necrosis factor-alpha and interferon-gamma in bone marrow cells synergistically inhibits neointimal formation following vascular injury.
Cardiovasc Res,80:175-180 2008
Author:Murayama H, Takahashi M, Takamoto M, Shiba Y, Ise H, Koyama J, Tagawa Y, Iwakura Y, Ikeda U.


Bone marrow-derived CXCR4(+) cells mobilized by macrophage colony-stimulating factor participate in the reduction of infarct area and improvement of cardiac remodeling after myocardial infarction in mice
AMERICAN JOURNAL OF PATHOLOGY,171(3):755-766 2007(Sep.)
Author:Morimoto, Hajime; Takahashi, Masafumi; Shiba, Yuji; Izawa, Atsushi; Ise, Hirohiko; Hongo, Minoru; Hatake, Kiyohiko; Motoyoshi, Kazuo; Ikeda, Uichi;


M-CSF accelerates neointimal formation in the early phase after vascular injury in mice: the critical role of the SDF-1-CXCR4 system.
Arterioscler Thromb Vasc Biol,27:283-289 2007
Author:Shiba Y, Takahashi M, Yoshioka T, Yajima N, Morimoto H, Izawa A, Ise H, Hatake K, Motoyoshi K, Ikeda U.


Others
幹細胞由来心筋細胞移植による不整脈抑制作用
週刊医学のあゆみ , 248(2):161-162 2014
Author:柴 祐司