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SAITO NAOTO

Academic OrganizationDepartment of Applied Physical Therapy, Shinshu University School of Health SciencesTEL
Education and Research OrganizationInstitute for Biomedical Sciences, Interdisciplinary Cluster for Cutting Edge Research, Shinshu UniversityFAX
PositionProfessor and DirectorMail Addresssaitoko@shinshu-u.ac.jp
AddressAsahi 3-1-1, Matsumoto, 390-8621 JapanWeb sitehttp://www.shinshu-u.ac.jp/institution/ibs/

Modified:11/30/2021

Profile

Assigned Class
Department of Biomedical Engineering, Graduate School of Medicine, Science and Technology, Shinshu University
Department of Biomedical Engineering (Master's Program), Graduate School of Science and Technology, Shinshu University
Research Group
Biocompatible System Engineering
Research Field
Orthopaedic surgery
Rehabilitation science/Welfare engineering
Biomedical engineering/ Biomaterial science and engineering
Nanobioscience
General medical chemistry
Academic Background
College
Shinshu University , (School of Medicine) , 1988

Degree
Doctor of Medicine , Shinshu University (Japan)

Research

Books, Articles, etc.
Books
Thin carbon fiber web that functions as a scaffold for tissue regeneration, Advances in Medicine and Biology 11 , 301-310
Nova Science Publishers, Inc., New York 2011
Author:Saito N, Aoki K, Usui Y, Shimizu M, Hara K, Narita N, Ogihara N, Nakamura K, Ishigaki N, Kato H, Haniu H, Kim C, Taruta S, Kim YA, Endo M


Application of carbon nanotubes on scaffolds for bone tissue regeneration, Bone regeneration: growth factors, augmentation procedures and tissue engineering applications , pp 275-284
Nova Science Publishers, Inc., New York 2010
Author:Saito N, Usui Y, Aoki K, Narita N, Shimizu M, Hara K, Ogiwara N, Nakamura K, Ishigaki N, Kato H, Haniu H, Taruta S, Endo M


New technology for bone tissue regeneration using cytokines and their drug delivery systems. In: Mashkevich BO (ed), Drug delivery research advances., pp 227-241
Nova Science Publishers, Inc., New York 2007
Author:.Saito N, Murakami N, Takaoka K.


New synthetic biodegradable polymers for bone morphogenetic protein delivery systems. Yaszemski MJ, Trantolo DJ, Lewandrowski KU, Hasirci V, Altobelli DE, Wise DL, eds: Tissue engineering and novel delivery systems., pp 475-482
Marcel Dekker inc, New York 2004
Author:Saito N, Horiuchi H, Murakami N, Takahashi J, Okada T, Nozaki K, Takaoka


New synthetic degradable polymers as carrier materials for BMP. In Wise DL(ed), Biomaterials engineering and devices: human applications, vol 1., pp 239-249
The Humana Press, New Jersey 2000
Author:Takaoka K, Miyamoto S, Saito N, Okada T.


Bone-inducing implants: new synthetic absorbable poly-D,L-lactic acid-polyethylene glycol block copolymers as BMP-carriers. In Ikada Y, Okano T(eds), Tissue engineering for therapeutic use, vol 3., pp 141-151
Elsevier Science B.V., Amsterdam 1999
Author:Takaoka K, Saito N, Miyamoto S, Yoshikawa H, Okada T.


Articles
Isolated lymphatic vessel lumen perfusion system for assessing nanomaterial movements and nanomaterial-induced responses in lymphatic vessels
Nano Today,36:101018 2021
Author:Kuroda C, Ajima K, Ueda K, Sobajima A, Yoshida K, Kamanaka T, Sasaki J, Ishida H, Haniu H, Okamoto M, Aoki K, Kato H, Saito N


Structurally different lysophosphatidylethanolamine species stimulate neurite outgrowth in cultured cortical neurons via distinct G-protein-coupled receptors and signaling cascades
Biochem Biophys Res Commun,1:179-185 2021
Author:Hisano K, Kawase S, Mimura T, Yoshida H, Yamada H, Haniu H, Tsukahara T, Kurihara T, Matsuda Y, Saito N, Uemura T


Ibandronate-loaded carbon nanohorns fabricated using calcium phosphates as a mediator and their effects on macrophages and osteoclasts
ACS Appl Mater Interfaces,13:3701-3712 2021
Author:Nakamura M, Ueda K, Yamamoto Y, Aoki K, Zhang M, Saito N, Yudasaka M


Evaluation of MC3T3-E1 cell osteogenesis in different cell culture media
Int J Mol Sci,22:7752 2021
Author:Izumiya M, Haniu M, Ueda K, Ishida H, Ma C, Ideta H, Sobajima A, Ueshiba K, Uemura T, Saito N, H, Haniu H.


Biodegradable polymers as drug delivery systems for bone regeneration.
Pharmaceutics,12:95 2020
Author:Aoki K, Saito N


Biocompatibility and carcinogenicity of carbon nanotubes as biomaterials.
Nanomaterials-Basal,10:264 2020
Author:Aoki K, Saito N


The use of electrospun nanofibers in bone regeneration, with a focus on carbon fibers.
Nanomaterials-Basal,10:562 2020
Author:Aoki K, Haniu H, Kim YA, Saito N.


Applications of carbon nanotubes in bone regenerative medicine.
Nanomaterials-Basal,10:659 2020
Author:Tanaka M, Aoki K, Haniu H, Kamanaka T, Takizawa T, Sobajima A, Yoshida K, Okamoto M, Kato H, Saito N.


A review of t-cell related therapy for osteosarcoma.
Int J Mol Sci,21:4877 2020
Author:Yoshida K, Okamoto M, Aoki K, Takahashi J, Saito N.


Anatomical remnant-preserving double-bundle ACL reconstruction with a new remnant augmentation technique.
Arthrosc Tech,9:e283-e290 2020
Author:Tensho K, Iwaasa T, Shimodaira H, Koyama S, Horiuchi H, Takahashi J, Saito N.


Anti-PD-1 antibody decreases tumour-infiltrating regulatory T cells.
BMC Cancer,20:25 2020
Author:Yoshida K, Okamoto M, Sasaki J, Kuroda C, Ishida H, Ueda K, Ideta H, Kamanaka T, Sobajima A, Takizawa T, Tanaka M, Aoki K, Uemura T, Kato H, Haniu H, Saito N.


Cellular responses of human lymphatic endothelial cells to carbon nanomaterials.
Nanomaterials-Basal,14:1374 2020
Author:Sano M, Izumiya M, Haniu H, Ueda K, Konishi K, Ishida H, Kuroda C, Uemura T, Aoki K, Matsuda Y, Saito N.


Aperture elongation of the femoral tunnel on the lateral cortex in anatomical double-bundle anterior cruciate ligament reconstruction using the outside-in technique.
Medicine,99:e22053 2020
Author:Tensho K, Akaoka Y, Iwaasa T, Koyama S, Shimodaira H, Horiuchi H, Saito N.


Carbon fibers for treatment of cancer metastasis in bone.
RSC Adv,10:33071-33079 2020
Author:Kamanaka T, Haniu H, Tanaka M, Takizawa T, Aoki K, Okamoto M, Sobajima A, Yoshida K, Ideta H, Mimura T, Ishida H, Ueda K, Uemura T, Kim J. H., Kim Y. A., Kato H, Saito N.


Carbon nanotube-based biomaterials for orthopaedic applications
J Mater Chem B,8:9227-9238 2020
Author:Aoki K, Ogihara N, Tanaka M, Haniu H, Saito N


Multiwall carbon nanotube composites as artificial joint materials
ACS Biomater Sci Eng,6:7032-7040 2020
Author:Sobajima A, Okihara T, Moriyama S, Nishimura N, Osawa T, Miyamae M, Haniu H, Aoki K, Tanaka M, Usui Y, Sako K, Kato H, Saito N


Clinical outcome of osteosarcoma and its correlation with programmed death-ligand 1 and T cell activation markers.
Oncotargets Ther,12:2513-2518 2019
Author:Yoshida K, Okamoto M, Sasaki J, Kuroda C, Ishida H, Ueda K, Okano S, Ideta H, Kamanaka T, Sobajima A, Takizawa T, Kito M, Aoki K, Uemura T, Haniu H, Kato H, Saito N.


Organ accumulation and carcinogenicity of highly dispersed multi-walled carbon nanotubes administered intravenously in transgenic rasH2 mice.
Int J Nanomed,2019(14):6465–6480 2019
Author:Sobajima A, Haniu H, Nomura H, Tanaka M, Takizawa T, Kamanaka T, Aoki K, Okamoto M, Yoshida K, Sasaki J, Ajima K, Kuroda C, Ishida H, Okano S, Ueda K, Kato H, Saito N.


In vitro and in vivo evaluation of starfish bone-derived β-tricalcium phosphate as a bone substitute material.
Materials,11:E1881 2019
Author:Ishida H, Haniu H, Takeuchi A, Ueda K, Sano M, Tanaka M, Takizawa T, Sobajima A, Kamanaka T, Saito N.


The interrelationship between anterior cruciate ligament tibial footprint and anterolateral meniscal root insertions: quantitative, morphological and positional analyses using 3-dimensional computed tomography images.
Knee,26:969-977 2019
Author:Tensho K, Iwaasa T, Koyama S, Yoshida K, Shimodaira H, Horiuchi H, Kato H, Saito N, Fukushima N.


Different aggregation and shape characteristics of carbon materials affect biological responses in RAW264 cells
Int J Nanomed,13:6079-6088 2018
Author:Kuroda C, Ueda K, Haniu H, Ishida H, Okano S, Takizawa T, Sobajima A, Kamanaka H, Yoshida K, Okamoto M, Tsukahara T, Matsuda Y, Aoki K, Kato H, Saito N


Lateralization of the tibial tubercle in recurrent patellar dislocation: verification using multiple evaluative methods for the tibial tubercle
J Bone Joint Surg Am,100:e58 2018
Author:Tensho K, Shimodaira H, Akaoka Y, Koyama S, Hatanaka D, Ikegami S, Kato H, Saito N


The acetabular fossa may not be located at the true center of the acetabulum: a detailed analysis using preoperative CT images
J Bone Joint Surg Am,100:e27 2018
Author:Shimodaira H, Tensho K, Akaoka Y, Koyama S, Maruyama M, Kato H, Saito N


A case of prefemoral fat pad impingement syndrome caused by hyperplastic fat pad.
Case Rep Orthop,2018:3583049 2018
Author:Koyama S, Tensho K, Shimodaira H, Iwaasa T, Horiuch H, Kato H, Saito N.


Titanium fiber plates for bone tissue repair
Adv Mater,30:1703608 2017
Author:Takizawa T, Nakayama N, Haniu H, Aoki K, Okamoto M, Nomura H, Tanaka M, Sobajima A, Yoshida K, Kamanaka T, Ajima K, Oishi A, Kuroda C, Ishida H, Okano S, Kobayashi S, Kato H, Saito N


Impact of extracellular matrix on engraftment and maturation of pluripotent stem cell-derived cardiomyocytes in a rat myocardial infarct model
Sci Rep-UK,7:8630 2017
Author:Ogasawara T, Okano S, Ichimura H, Kadota S, Tanaka Y, Minami I, Uesugi M, Wada Y, Saito N, Okada K, Kuwahara K, Shiba Y


In vitro and in vivo evaluation of a three-dimensional porous multi-walled carbon nanotube scaffold for bone regeneration
Nanomaterials-Basel,l7:46 2017
Author:Tanaka M, Sato Y, Zhang M, Haniu H, Okamoto M, Aoki K, Takizawa T, Yoshida K, Sobajima A, Kamanaka T, Kato H, Saito N


A three-dimensional block structure consisting exclusively of carbon nanotubes serving as bone regeneration scaffold and as bone defect filler
PLoS One,12:e0172601 2017
Author:Tanaka M, Sato Y, Haniu H, Nomura H, Kobayashi S, Takanashi S, Okamoto M, Takizawa T, Aoki K, Usui Y, Oishi A, Kato H, Saito N


Physico-chemical, in vitro, and in vivo evaluation of a 3d unidirectional porous hydroxyapatite scaffold for bone regeneration
Materials,10:33 2017
Author:Tanaka M, Haniu H, Kamanaka T, Takizawa T, Sobajima A, Yoshida K, Aoki K, Okamoto M, Kato H, Saito N


The dispersion state of tangled multi-walled carbon nanotubes affects their cytotoxicity.
Nanomaterials-Basel.,6:219 2016
Author:Kuroda C, Haniu H, Ajima K, Tanaka M, Sobajima A, Ishida H, Tsukahara T, Matsuda Y, Aoki K, Kato H, Saito N.


Remnant-preserving tibial tunnel positioning using anatomical landmarks in double-bundle anterior cruciate ligament reconstruction.
Arthroscopy,32(9):1822-1830 2016
Author:Shimodaira H, Tensho K, Akaoka Y, Takanashi S, Kato H, Saito N.


Differentiation of chemical reaction activity of various carbon nanotubes using redox potential: classification by physical and chemical structures
CARBON,95:302-308 2015(Dec.)
Author:Tsuruoka S, Matsumoto H, Castranova V, Porter DW, Yanagisawa T, Saito N, Kobayashi S, Endo M


Radical scavenging reaction kinetics with multi-walled carbon nanotubes
CARBON,83:232-239 2015(Mar.)
Author:Tsuruoka S, Matsumoto H, Koyama K, Akiba E, Yanagisawa T, Cassee FR, Saito N, Usui Y, Kobayashi S, Porter DW, Castranova V, Endo M


Influence of pmsa-based polymer on the settling velocity of cnt in aqueous media.
Mater Trans,56(12):2006-2009 2015
Author:Nishimura N, Takeda S, Teranishi T, Hayashi H, Saito N, Kishimoto A.


What components comprise the measurement of the tibial tuberosity-trochlear groove distance in a patellar dislocation population?
JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME,97(17):1441-1448 2015
Author:Tensho K, Akaoka Y, Shimodaira H, Takanashi S, Ikegami S, Kato H, Saito N


Specific biological responses of the synovial membrane to carbon nanotubes
SCIENTIFIC REPORTS,5:14314 2015
Author:Nomura H, Takanashi S, Tanaka M, Haniu H, Aoki K, Okamoto M, Kobayashi S, Takizawa T, Usui Y, Oishi A, Kato H, Saito N


An advanced in-situ imaging method using heavy metal doped hollow tubes to evaluate the biokinetics of carbon nanotubes in vivo
NPG ASIA MATERIALS,7:e203 2015
Author:Kobayashi S, Tsuruoka S, Usui Y, Haniu H, Aoki K, Takanashi S, Okamoto M, Nomura H, Tanaka M, Aiso S, Saito M, Kato H, Saito N


Endocytosis of multiwalled carbon nanotubes in bronchial epithelial and mesothelial cells
BIOMED RESEARCH INTERNATIONAL,2015:793186 2015
Author:Maruyama K, Haniu H, Saito N, Matsuda Y, Tsukahara T, Kobayashi S, Tanaka M, Aoki K, Takanashi S, Okamoto M, Kato H


Bony Landmarks of the Anterior Cruciate Ligament Tibial Footprint A Detailed Analysis Comparing 3-Dimensional Computed Tomography Images to Visual and Histological Evaluations
AMERICAN JOURNAL OF SPORTS MEDICINE,42(6):1433-1440 2014(Jun.)
Author:Tensho, K; Shimodaira, H; Aoki, T; Narita, N; Kato, H; Kakegawa, A; Fukushima, N; Moriizumi, T; Fujii, M; Fujinaga, Y; Saito, N


Safe Clinical Use of Carbon Nanotubes as Innovative Biomaterials
CHEMICAL REVIEWS,114(11):6040-6079 2014(Jun.)
Author:Saito, N; Haniu, H; Usui, Y; Aoki, K; Hara, K; Takanashi, S; Shimizu, M; Narita, N; Okamoto, M; Kobayashi, S; Nomura, H; Kato, H; Nishimura, N; Taruta, S; Endo, M


Influence of CNF content on microstructure and fracture toughness of CNF/alumina composites
JOURNAL OF THE CERAMIC SOCIETY OF JAPAN,122(1424):292-299 2014(Apr.)
Author:Ueda, N; Yamakami, T; Yamaguchi, T; Usui, Y; Aoki, K; Endo, M; Saito, N; Taruta, S


Noncanonical Wnt5a enhances Wnt/beta-catenin signaling during osteoblastogenesis
SCIENTIFIC REPORTS,4:4493 2014(Mar.)
Author:Okamoto, M; Udagawa, N; Uehara, S; Maeda, K; Yamashita, T; Nakamichi, Y; Kato, H; Saito, N; Minami, Y; Takahashi, N; Kobayashi, Y


Snapping pes syndrome after total knee arthroplasty
KNEE SURGERY SPORTS TRAUMATOLOGY ARTHROSCOPY,22(1):192-194 2014(Jan.)
Author:Tensho K, Aoki T, Morioka S, Narita N, Kato H, Saito N


Early post-operative intra-tunnel migration of the EndoButton after anatomical double-bundle anterior cruciate ligament reconstruction
JBJS CASE CONNECTOR,4(4):e88 2014
Author:Akaoka Y, Tensho K, Shimodaira H, Aoki T, Takanashi S, Kato H, Saito N


Biological responses according to the shape and size of carbon nanotubes in BEAS-2B and MESO-1 cells
INTERNATIONAL JOURNAL OF NANOMEDICINE,9:1979-1990 2014
Author:Haniu, H; Saito, N; Matsuda, Y; Tsukahara, T; Usui, Y; Maruyama, K; Takanashi, S; Aoki, K; Kobayashi, S; Nomura, H; Tanaka, M; Okamoto, M; Kato, H


Effect of aspect ratio on the internal structure of titanium fiber formed by the compression shearing method at room temperature
JOURNAL OF THE JAPANESE SOCIETY FOR EXPERIMENTAL MECHANICS,13(Special Issue):s126-s130 2013
Author:Nakayama N, Izawa N, Horita M, Saito N, Miki H, Takeishi H


Culture medium type affects endocytosis of multi-walled carbon nanotubes in BEAS-2B cells and subsequent biological response
TOXICOLOGY IN VITRO,27(6):1679-1685 2013
Author:Haniu, Hisao; Saito, Naoto; Matsuda, Yoshikazu; Tsukahara, Tamotsu; Maruyama, Kayo; Usui, Yuki; Aoki, Kaoru; Takanashi, Seiji; Kobayashi, Shinsuke; Nomura, Hiroki; Okamoto, Masanori; Shimizu, Masayuki; Kato, Hiroyuki


Effect of shearing strain on mechanical properties of titanium thin plate by compression shearing method at room temperature.
STEEL RESEARCH INTERNATIONAL,Special Edition Metal Forming:803-806 2012
Author:Horita M, Nakayama N, Saito N, Miki H, Miyazaki T, Takeishi H.


Carbon nanotubes induce bone calcification by bidirectional interaction with osteoblasts
ADVANCED MATERIALS,24:2176-2185 2012
Author:Shimizu M, Kobayashi Y, Mizoguchi T, Nakamura H, Kawahara I, Narita N, Usui Y, Aoki K, Hara K, Haniu H, Ogihara N, Ishigaki N, Nakamura K, Kato H, Kawakubo M, Dohi Y, Taruta S, Kim YA, Endo M, Ozawa H, Udagawa N, Takahashi N, Saito N


Carcinogenicity evaluation for the application of carbon nanotubes as biomaterials in rasH2 mice
SCIENTIFIC REPORTS,2:498 2012
Author:Takanashi S, Hara K, Aoki K, Usui Y, Shimizu M, Haniu H, Ogihara N, Ishigaki N, Nakamura K, Okamoto M, Kobayashi S, Kato H, Sano K, Nishimura N, Tsutsumi H, Machida K Saito N


Microstructure development and fracture toughness of acid-treated carbon nanofibers/alumina composites
JOURNAL OF THE CERAMIC SOCIETY OF JAPAN,120(12):560-568 2012
Author:Ueda N, Yamakami T, Yamaguchi T, Kitajima K, Usui Y, Aoki K, Endo M, Saito N, Taruta S


Basic Potentialof Carbon Nanotubes in Tissue Engineering Applications
JOURNAL OF NANOMATERIALS,2012:34374 2012
Author:Haniu, Hisao; Saito, Naoto; Matsuda, Yoshikazu; Tsukahara, Tamotsu; Usui, Yuki; Narita, Nobuyo; Hara, Kazuo; Aoki, Kaoru; Shimizu, Masayuki; Ogihara, Nobuhide; Takanashi, Seiji; Okamoto, Masanori; Kobayashi, Shinsuke; Ishigaki, Norio; Nakamura, Koichi; Kato, Hiroyuki


Carbon nanotubes innovate on medical technology
MEDICINAL CHEMISTRY,2:1-6 2012
Author:Usui Y, Haniu H, Tsuruoka S, Saito N


Biocompatibility and bone tissue compatibility of alumina ceramics reinforced with carbon nanotubes
NANOMEDICINE,7:981-993 2012
Author:Ogihara N, Usui Y, Aoki K, Shimizu M, Narita N, Hara K, Nakamura K, Ishigaki N, Takanashi S, Okamoto M, Kato H, Haniu H, Ogiwara N, Nakayama N, Taruta S, Saito N.


Manufacturing strategy for multi-walled carbon nanotubes as a biocompatible and innovative material
JOURNAL OF NANOTECHNOLOGY,937819:1-6 2012
Author:Haniu H, Saito N, Matsuda Y, Usui Y, Aoki K, ShimizuM, Ogihara N, Hara K, Takanashi S, Okamoto M, Nakamura K, Ishigaki N, Tsukahara T, Kato H.


Application of carbon fibers to biomaterials: new era of nano-level control of carbon fibers after 30-years of development
CHEMICAL SOCIETY REVIEWS,40(7):3824-3834 2011
Author:Saito N, Aoki K, Usui Y, Shimizu M,Hara K, Narita N, Ogihara N,Nakamura K, Ishigaki N, Kato H, Haniu H, Taruta S, Kim YA, Endo M.


Toxicoproteomic evaluation of carbon nanomaterials in vitro
JOURNAL OF PROTEOMICS,74(12):2703-2712 2011
Author:Haniu H, Matsuda Y, Usui Y, Aoki K, Shimizu M, Ogihara N, Hara K, Okamoto M,Takanashi S, Ishigaki N, Nakamura K, Kato H, Saito N.


Deposition of apatite on carbon nanofibers in simulated body fluid
JOURNAL OF NANOMATERIALS,935320:1-8 2011
Author:Taruta S, Kidokoro K, Yamakami T, Yamaguchi T, Kitajima K, Endo M, Saito N.


Effect of dispersants of multi-walled carbon nanotubes on cellular uptake and biological responses
INTERNATIONAL JOURNAL OF NANOMEDICINE,6(1):3295-3307 2011
Author:Haniu H, Saito N, Matsuda Y, Kim YA, Park KC, Tsukahara T, Usui Y, Aoki K, Shimizu M, Ogihara N, Hara K, Takanashi S, Okamoto M, Ishigaki N, Nakamura K, Kato H.


Elucidation mechanism of different biological responses to multi-walled carbon nanotubes using four cell lines
INTERNATIONAL JOURNAL OF NANOMEDICINE,6:3487-3497 2011
Author:Haniu H, Saito N, Matsuda Y, Kim YA, Park KC, Tsukahara T, Usui Y, Aoki K, Shimizu M, Ogihara N, Hara K, Takanashi S, Okamoto M, Ishigaki N, Nakamura K, Kato H.


DJ-1 as a potential biomarker for the development of biocompatible multiwalled carbon nanotubes
INTERNATIONAL JOURNAL OF NANOMEDICINE,6(1):2689-2695 2011
Author:Haniu H, Tsukahara T, Matsuda Y, Usui Y, Aoki K, Shimizu M, Ogihara N, Hara K, Takanashi S, Okamoto M, Ishigaki N, Nakamura K, Kato H, Saito N.


Evaluation of CNTtoxicity in comparison to tattoo ink nanoparticles for use as a biomaterial
MATERIALS TODAY,14:434-440 2011
Author:Hara K, Aoki K, Usui Y, Shimizu M, Narita N, Ogihara N, Nakamura K, Ishigaki N, Sano K, Haniu H, Kato H, Nishimura N, Kim YA, Taruta S, Saito N.


Analysis of pelvic movement in the elderly duringwalking using a posture monitoring system equipped with a triaxial accelerometer and a gyroscope
JOURNAL OF BIOMECHANICS,44:1788-1792 2011
Author:Ishigaki N, Kimura T, Usui Y, Aoki K, Narita N, Shimizu M, Hara K, Ogihara N, Nakamura K, Kato H, Ohira M, Yokokawa Y, Miyoshi K, Murakami N, Okada S, Nakamura T, Saito N.


Anatomic double-bundle anterior cruciate ligament reconstruction, using CT-based navigation and fiducial markers
KNEE SURGERY SPORTS TRAUMATOLOGY ARTHROSCOPY,19:378–383 2011
Author:Tensho K, Kodaira H, Yasuda G, Yoshimura Y, Narita N, Morioka S, Kato H, Saito N


Fabrication and mechanical properties of high-dispersion-treated carbon nanofiber/alumina composites
JOURNAL OF THE CERAMIC SOCIETY OF JAPAN,118(9):847-854 2010
Author:Ueda N, Yamakami T, Yamaguchi T, Kitajima K, Usui Y, Aoki K, Nakanishi T, Miyaji F, Endo M, Saito N


Multi-walled carbon nanotubes specifically inhibit osteoclast differentiation and function
NANO LETTERS,9(4):1406-1413 2009
Author:Narita N, Kobayashi Y, Nakamura H, Maeda K, Ishihara A, Mizoguchi T, Usui Y, Aoki K, Shimizu M, Kato H, Ozawa H, Udagawa N, Endo M, Takahashi N, Saito N


Carbon nanotubes: Biomaterial applications
CHEMICAL SOCIETY REVIEWS,38(7):1897-1903 2009
Author:Saito, N; Usui, Y; Aoki, K; Narita, N; Shimizu, M; Hara, K; Ogiwara, N; Nakamura, K; Ishigaki, N; Kato, H; Taruta, S; Endo, M


A Thin Carbon Fiber Web as a Scaffold for Bone Tissue Regeneration
SMALL,5(13):1540-1546 2009
Author:Aoki, K; Usui, Y; Narita, N; Ogiwara, N; Ishigaki, N; Nakamura, K; Kato, H; Sano, K; Ogiwara, N; Kametani, K; Kim, C; Taruta, S; Kim, YA; Endo, M; Saito, N


Carbon nanotubes for biomaterials in contact with bone
CURRENT MEDICINAL CHEMISTRY,15(5):523-527 2008
Author:Saito, N; Usui, Y;Aoki, K; Narita, N; Shimizu, M; Ogiwara, N; Nakamura,K; Ishigaki, N; Kato, H; Taruta, S; Endo, M


Carbon nanotubes with high bone-tissue compatibility and bone-formation acceleration effect
SMALL,4(2):240-246 2008
Author:Usui, Y; Aoki, K; Narita, N; Murakami, N; Nakamura, I; Nakamura, K; Ishigaki, N; Yamazaki, H; Horiuchi, H; Kato, H; Taruta, S; Kim, YA; Endo, M; Saito, N


Brothers with genu recurvatum
KNEE,14(6):500-501 2007
Author:Saito, N; Tensyo, K; Horiuchi, H; Aoki, K; Kobayashi, S; Kato, H; Kosh, T


Coordinate expression of BMP-2, BMP receptors and Noggin in normal mouse spine
JOURNAL OF CLINICAL NEUROSCIENCE,13(2):250-256 2006
Author:Nakamura Y, Nakaya H, Saito N, Wakitani S.


Potentiation of the activity of bone morphogenetic protein-2 in bone regeneration by a PLA-PEG/hydroxyapatite composite
BIOMATERIALS,26(1):73-79 2005
Author:Kaito, T; Myoui, A; Takaoka, K; Saito, N; Nishikawa, M; Tamai, N; Ohgushi, H; Yoshikawa, H


Use of bone morphogenetic protein 2 and diffusion chambers to engineer cartilage tissue for the repair of defects in articular cartilage
ARTHRITIS AND RHEUMATISM,52(1):155-163 2005
Author:Nawata, M; Wakitani, S;Nakaya, H; Tanigami, A; Seki, T; Nakamura, Y; Saito, N; Sano, K; Hidaka, E; Takaoka, K


Synthetic biodegradable polymers as drug delivery systems for bone morphogenetic proteins
ADVANCED DRUG DELIVERY REVIEWS,57(7):1037-1048 2005
Author:Saito N, Murakami N, Takahashi J, Horiuchi H, Ota H, Kato H, Okada T, Nozaki K, Takaoka K.


Expression profiles of BMP-related molecules induced by BMP-2 or-4 in muscle-derived primary culture cells
JOURNAL OF BONE AND MINERAL METABOLISM,23(6):426-434 2005
Author:Nakamura Y, Wakitani S, Saito N, Takaoka K.


The effects of heat on the biological activity of recombinant human bone morphogenetic protein-2
JOURNAL OF BONE AND MINERAL METABOLISM,23(6):420-425 2005
Author:Ohta H,Wakitani S, Tensho K, Horiuchi H, Wakabayashi S, Saito N, Nakamura Y, Nozaki K, Imai Y, Takaoka K.


Heterotopic ossification in the knee following encephalitis: a case report with a 10-year follow-up
KNEE,11(1):63-65 2004
Author:Saito, N; Horiuchi, H; Takahashi, H


Continuous local cooling for pain relief following total hip arthroplasty
JOURNAL OF ARTHROPLASTY,19(3):334-337 2004
Author:Saito, N; Horiuchi, H; Kobayashi, S; Nawata, M; Takaoka, K


Enhancement of recombinant human bone morphogenetic protein-2 (rhBMP-2)-induced new bone formation by concurrent treatment with parathyroid hormone and a phosphodiesterase inhibitor, pentoxifylline
JOURNAL OF BONE AND MINERAL METABOLISM,22(4):329-334 2004
Author:Horiuchi, H; Saito, N; Kinoshita, T; Wakabayashi, S; Tsutsumimoto, T; Otsuru, S; Takaoka, K


Osteonecrosis of the femoral head in Japanese adults after liver transplantation: a preliminary report
JOURNAL OF ORTHOPAEDIC SCIENCE,9(2):119-121 2004
Author:Horiuchi, H; Hashikura, Y; Hisa, K; Saito, N; Ikegami, T; Nakazawa, Y; Karakida, O; Kobayashi, S; Nawata, M; Kawasaki, S; Takaoka, K


Locking of the knee couasedby localized pigmented villonodular synovitis: a case report
MODERN RHEUMATOLOGY,14:184-186 2004
Author:Horiuchi H, Nawata M, Kamijo T, Saito N, Wakitani S, Kobayashi S, Shimizu T, Koto H.


Total hip arthroplasty with bulk femoral head autograft for acetabular reconstruction in DDH: surgical technique
JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME,86 Supple 1:11-17 2004
Author:Kobayashi S, Saito N, Nawata M, Horiuchi H, Iorio R, Takaoka K.


Trabecular minimodeling in human iliac bone
BONE,32(2):163-169 2003
Author:Kobayashi, S; Takahashi, HE; Ito, A; Saito, N; Nawata, M; Horiuchi, H; Ohta, H; Ito, A; Iorio, R; Yamamoto, N; Takaoka, K


Total hip arthroplasty with bulk femoral head autograft for acetabular reconstruction in developmental dysplasia of the hip
JOURNAL OF BONE AND JOINT SURGERY-AMERICANVOLUME,85A(4):615-621 2003
Author:Kobayashi, S; Saito, N; Nawata, M; Horiuchi, H; Iorio, R; Takaoka, K


Anterior thoracic spinal fusion in dogs by injection of recombinant human bone morphogenetic protein-2 and a synthetic polymer
JOURNAL OF SPINAL DISORDERS&TECHNIQUES,16(2):137-143 2003
Author:Takahashi, J; Saito, N; Ebara, S; Kinoshita, T; Itoh, H; Okada, T; Nozaki, K; Takaoka, K


New synthetic biodegradable polymers as BMP carriers for bone tissue engineering
BIOMATERIALS,24(13):2287-2293 2003
Author:Saito, N; Takaoka, K


Repair of a proximal femoral bone defect in dogs using a porous surfaced prosthesis in combination with recombinant BMP-2 and a synthetic polymer carrier
BIOMATERIALS,24(13):2153-2159 2003
Author:Murakami, N; Saito, N; Takahashi, J; Ota, H; Horiuchi, H; Nawata, M; Okada, T; Nozaki, K; Takaoka, K


Local bone formation by injection of recombinant human bone morphogenetic protein-2 contained in polymer carriers
BONE,32(4):381-386 2003
Author:Saito, N; Okada, T; Horiuchi, H; Ota, H; Takahashi, J; Murakami, N; Nawata, M; Kojima, S; Nozaki, K; Takaoka, K


Sequential changes in periprosthetic bone mineral density following total hip arthroplasty: a 3-year follow-up
JOURNAL OF BONE AND MINERAL METABOLISM,21(4):229-233 2003
Author:Ohta, H; Kobayashi, S; Saito, N; Nawata, M; Horiuchi, H; Takaoka, K


Osteoprotegerin regulates bone formation through a coupling mechanism with bone resorption
ENDOCRINOLOGY,144(12):5441-5449 2003
Author:Nakamura, M; Udagawa, N; Matsuura, S; Mogi, M; Nakamura, H; Horiuchi, H; Saito, N; Hiraoka, BY; Kobayashi, Y; Takaoka, K; Ozawa, H; Miyazawa, H; Takahashi, N


Extraskeletal chondroma of the hand accompanied by proliferating chondroblast-like cells with an eleven-year follow-up
AMERICAN JOURNAL OF CASE REPORTS,4:66-68 2003
Author:Saito N, Horiuchi H, Toriumi H, Miyasaka T.


Effect of phosphodiesterase inhibitor-4, Rolipram, on new bone formations by recombinant human bone morphogenetic protein-2
BONE,30(4):589-593 2002
Author:Horiuchi, H; Saito, N; Kinoshita, T; Wakabayashi, S; Yotsumoto, N; Takaoka, K


Avascular necrosis of the femoral head in a patient with Fabry's disease - Identification of ceramide trihexoside in the bone by delayed-extraction matrix-assisted laser desorption ionization-time-of-flight mass spectrometry
ARTHRITIS AND RHEUMATISM,46(7):1922-1925 2002
Author:Horiuchi, H; Saito, N; Kobayashi, S; Ota, H; Taketomi, T; Takaoka, K


Repair of segmental defects in rabbit humeri with titanium fiber mesh cylinders containing recombinant human bone morphogenetic protein-2 (rhBMP-2) and a synthetic polymer
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A,62(2):169-174 2002
Author:Murakami, N; Saito, N; Horiuchi, H; Okada, T; Nozaki, K; Takaoka, K


Three-dimentional computed tomography evaluation of bony birth canal morphologic deformity (small pelvic cavity) after dome pelvic osteotomy for developmental dysplasia of the hip
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY,187:1591-1595 2002
Author:Kojima S, Kobayashi S, Saito N, Nawata M, Horiuchi H, Takaoka K.


Enhancement of bone morphogenetic protein-2-induced new bone formation in mice by the phosphodiesterase inhibitor pentoxifylline
BONE,28(3):290-294 2001
Author:Horiuchi, H; Saito, N; Kinoshita, T; Wakabayashi, S; Tsutsumimoto, T; Takaoka, K


Progressive scoliosis in cri-du-chat syndrome over a 20-year follow-up period - A case report
SPINE,26(7):835-837 2001
Author:Saito, N; Ebara, S; Fukushima, Y; Wakui, K; Takaoka, K


A biodegradable polymer as a cytokine delivery system for inducing bone formation
NATURE BIOTECHNOLOGY,19(4):332-335 2001
Author:Saito, N; Okada,T; Horiuchi, H; Murakami, N; Takahashi, J; Nawata, M; Ota, H; Nozaki, K; Takaoka, K


Biodegradable poly-D,L-lacticacid-polyethylene glycol block copolymers as a BMP delivery system for inducing bone
JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME,83A:S92-S98 2001
Author:Saito, N; Okada, T; Horiuchi,H; Murakami, N; Takakashi, J; Nawata, M; Ota, H; Miyamoto, S; Nozaki, K; Takaoka, K


Morphological characteristics of the bony birth canal in patients with developmental dysplasia of the hip (DDH): investigation by three-dimensional CT
JOURNAL OF ORTHOPAEDIC SCIENCE,6:217-222 2001
Author:Kojima S, Kobayashi S, Saito N, Nawata M, Horiuchi H, Takaoka K.


Poor bone quality or hip structure as risk factors affecting survival of total-hip arthroplasty
LANCET,355(9214):1499-1504 2000
Author:Kobayashi S, Saito N, Horiuchi H, Iorio R, Takaoka K.


New synthetic absorbable polymers as BMP carriers: Plastic properties of poly-D,L-lactic acid-polyethylene glycol block copolymers
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A,47(1):104-110 1999
Author:Saito N, Okada T, Toba S, Miyamoto S, Takaoka K.


Natural history of scoliosis in spastic cerebral palsy
LANCET,351(9117):1687-1692 1998
Author:Saito N, Ebara S, Ohotsuka K, Kumeta H, Takaoka K.


Long-term bone remodeling around Charnley femoral prostheses: comparison of cementing techniques
ARCHIVES OF THE AMERICAN ACADEMY OF ORTHOPAEDIC SURGEONS,1:30-33 1997
Author:Kobayashi S, Takaoka K, Saito N, Hisa K.


Factors affecting aseptic failure of fixation after primary charnley totalhip arthroplasty - Multivariate survival analysis
JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME,79A(11):1618-1627 1997
Author:Kobayashi S, Takaoka K, Saito N, Hisa K.


Radiographic factors predicting non-union of displaced intracapsular femoral neck fracture
ARCHIVES OF ORTHOPAEDIC AND TRAUMA SURGERY,114:183-187 1995
Author:Saito N, Miyasaka T, Toriumi H.


Potential risk of medial cortex perforation due to peg position of morphometric tibial component in unicompartmental knee arthroplasty: a computer simulation study.
Knee Surg Sport Tr A
Author:Tensho K, Koyama S, Iwaasa T, Shimodaira H, Saito N, Horiuchi H, Takahashi J.


Antitumor effect of sclerostin against osteosarcoma.
Cancer,:in press-in press
Author:Ideta H, Yoshida K, Okamoto M, Sasaki J, Kito M, Aoki K, Yoshimura Y, Suzuki S, Tanaka A, Takazawa A, Haniu H, Uemura T, Takizawa T, Sobajima A, Kamanaka T, Takahashi J, Kato H, Saito N.