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YAZAWA Kenjiro

Academic OrganizationAcademic Assembly School of Science and Technology Institute of Textile Science and TechnologyTEL+81-268-21-5353
Education and Research OrganizationFaculty of Textile Science and Technology Division of Applied BiologyFAX
PositionAssociate ProfessorMail Addresskenjiro_yazawa@shinshu-u.ac.jp
Address3-15-1, Tokida, Ueda City 386-8567Web site

Profile

Assigned Class
Interdisciplinary Cluster for Cutting Edge Research Institute for Fiber Engineering
Research Field
Bio-related chemistry
Keywords:Silkworm silk , Spider silk
Current Subject
Mechanism of silk spinning system in vivo
Keywords:Silk , Spinning , Spider , Silkworm
Synthesis of artificial silk
Keywords:Artificial silk , Enzymatic synthesis , Polyalanine
Academic Societies
Academic Societies
日本シルク学会
繊維学会
日本野蚕学会
日本蚕糸学会
Academic Background
Graduate School
東京工業大学 , 2013

College
東京工業大学 , 2008

Degree
博士(工学) , 東京工業大学
Awards
2023 , 繊維学会奨励賞
2012 , International Symposium on Advanced Biological Engineering Best Poster Award
2012 , 東京工業大学GCOE成果発表会, 最優秀研究科長賞
2010 , 日本化学会, 春季年会, 学生講演賞
Research Career
Research Career
2023- , 信州大学 繊維学部 准教授
2018-2023 , 信州大学 繊維学部 テニュア・トラック助教
2014-2018 , 理化学研究所 特別研究員
2013-2014 , 山形大学 大学院 理工学研究科 プロジェクト研究員
2013-2013 , 山形大学 大学院 理工学研究科 研究支援者

Research

Books, Articles, etc.
Articles
Dry spinning of nucleotide-based fibers comprising the ion complex between biomass DNA and cationic lipid
ACS Sustainable Chemistry & Engineering 2023(Dec.)
Author:Kenjiro Yazawa and Takafumi Kamijo


Spider dragline silk fibres maintain rectangular columnar liquid crystalline phase
Liquid Crystals 2023(Jul.)
Author:Kenjiro Yazawa and Kazuchika Ohta


Wild silkworm cocoon waste conversion into tough regenerated silk fibers by solution spinning
Biomacromolecules,24(4):1700-1708 2023(Mar.)
Author:Kenjiro Yazawa, Shunsuke Iwata, Yasuo Gotoh


Silkworm cocoon waste revitalization: regenerated fibers using higher-molecular-weight fibroin achieve high strength and toughness
ACS Sustainable Chemistry & Engineering,11(6):2151-2159 2023(Feb.)
Author:Kenjiro Yazawa, Kento Nakayama, Yasuo Gotoh


1000 spider silkomes: linking sequences to silk physical properties
Science Advances,8(41):eabo6043 2022(Oct.)
Author:Kazuharu Arakawa, Nobuaki Kono, Ali D. Malay, Ayaka Tateishi, Nao Ifuku, Hiroyasu Masunaga, Ryota Sato, Kousuke Tsuchiya, Rintaro Ohtoshi, Daniel Pedrazzoli, Asaka Shinohara, Yusuke Ito, Hiroyuki Nakamura, Akio Tanikawa, Yuya Suzuki, Takeaki Ichikawa, Shohei Fujita, Masayuki Fujiwara, Masaru Tomita, Sean J. Blamires, Jo-Ann Chuah, Hamish Craig, Choon Pin Foong, Gabriele Greco, Juan Guan, Chris Holland, David L. Kaplan, Kumar Sudesh, Biman B. Mandal, Y. Norma-Rashid, Alia Nur Oktaviani, Rucsanda C. Preda, Nicola M. Pugno, Rangam Rajkhowa, Xiaoqin Wang, Kenjiro Yazawa, Zhaozhu Zheng, Keiji Numata


Cell adhesion behaviors on spider silk fibers, films, and nanofibers
Langmuir,38(25):7766-7774 2022(Jun.)
Author:Kenjiro Yazawa, Kosuke Hidaka, Jun Negishi


Electrospinning of spider silk-based nanofibers
Polymers for Advanced Technologies,33(9):2637-2644 2022(May)
Author:Kenjiro Yazawa, Saeka Mizukami, Masaaki Aoki, Yasushi Tamada


Eri silkworm spins mechanically robust silk fibers regardless of reeling speed
Journal of Experimental Biology,225(3):jeb243458 2022(Feb.)
Author:Kenjiro Yazawa, Yuka Tatebayashi, and Zenta Kajiura


Forcibly spun dragline silk fibers from web-building spider Trichonephila clavata ensure robustness irrespective of spinning speed and humidity
International Journal of Biological Macromolecules,168:550-557 2021(Jan.)
Author:Kenjiro Yazawa and Umi Sasaki


Pressure- and humidity-induced structural transition of silk fibroin
Polymer,211:123082 2020(Oct.)
Author:Kenjiro Yazawa and Kosuke Hidaka


Simultaneous effect of strain rate and humidity on the structure and mechanical behavior of spider silk
Communications Materials,1:10 2020(Mar.)
Author:Kenjiro Yazawa, Ali Malay, Hiroyasu Masunaga, Yusoff Norma-Rashid, and Keiji Numata


Molecular interactions and toughening mechanisms in silk fibroin-epoxy resin blend films
Biomacromolecules,20(6):2295-2304 2019(May)
Author:Kang Yang, Kenjiro Yazawa, Kosuke Tsuchiya, Keiji Numata, and Juan Guan


Entropy-driven mechanisms between disulfide-bond formation protein A (DsbA) and B (DsbB) in Escherichia coli
ACS Omega,4(5):8341-8349 2019(May)
Author:Kenjiro Yazawa and Hiroyuki Furusawa


Two birds with one stone: Spontaneous size separation and growth inhibition of femtosecond laser-generated surfactant-free metallic nanoparticles via ex situ SU-8 functionalization.
ACS Omega,3(9):10953-10966 2018(Sep.)
Author:Dongshi Zhang, Wonsuk Choi, Kenjiro Yazawa, Keiji Numata, Ayaka Tateishi, Sung-Hak Cho, Hsiu-Pen Lin, Yaw Kuen Li, Yoshihiro Ito, Koji Sugioka


Role of skin layers on mechanical properties and supercontraction of spider dragline silk fiber
Macromolecular Bioscience,18(9):1800220 2018(Sep.)
Author:Kenjiro Yazawa, Ali D. Malay, Hiroyasu Masunaga, and Keiji Numata


Combination of amorphous silk fiber spinning and postspinning crystallization for tough regenerated silk fibers
Biomacromolecules,19(6):2227-2237 2018(Apr.)
Author:Kenjiro Yazawa, Ali D. Malay, Nao Ifuku, Takaoki Ishii, Hiroyasu Masunaga, and Keiji Numata


Morphological and mechanical properties of flexible resilin joints on damselfly wings (Rhinocypha spp.)
Plos One,13(3):e0193147 2018(Mar.)
Author:Mamat-Noorhidayah, Kenjiro Yazawa, Keiji Numata, and Y. Norma-Rashid


Probing multiple binding modes of DNA hybridization: A comparison between single-molecule observations and ensemble measurements
ACS Omega,3(2):2084-2092 2018(Feb.)
Author:Kenjiro Yazawa and Hiroyuki Furusawa


Chemoenzymatic synthesis of a peptide containing nylon monomer units for thermally processable peptide material application
Polymer Chemistry,8(29):4172-4176 2017(May)
Author:Kenjiro Yazawa, Joan Gimenez-Dejoz, Hiroyasu Masunaga, Takaaki Hikima, and Keiji Numata


Relationships between physical properties and sequence in silkworm silks
Scientific Reports,6:27573-27584 2016(Jun.)
Author:Ali D. Malay, Ryota Sato, Kenjiro Yazawa, Hiroe Watanabe, Nao Ifuku, Hiroyasu Masunaga, Takaaki Hikima, Juan Guan, Biman B. Mandal, Siriporn Damrongsakkul, and Keiji Numata


Papain-catalyzed synthesis of polyglutamate containing a nylon monomer unit
Polymers,8(5):194-206 2016(May)
Author:Kenjiro Yazawa and Keiji Numata


Derivatization of proteinase K with heavy atoms enhances its thermal stability
ACS Catalysis,6(5):3036-3046 2016(Apr.)
Author:Kenjiro Yazawa, Michihiro Sugahara, Katsuhide Yutani, Michiyo Takehira, and Keiji Numata


Influence of water content on the β-sheet formation, thermal stability, water removal, and mechanical properties of silk materials
Biomacromolecules,17(3):1057-1066 2016(Feb.)
Author:Kenjiro Yazawa, Kana Ishida, Hiroyasu Masunaga, Takaaki Hikima, Keiji Numata


Crystal structure and physical properties of Antheraea yamamai silk fibers: long poly(alanine) sequences are partially in the crystalline region
Polymer,77:87-94 2015(Dec.)
Author:Keiji Numata, Ryota Sato, Kenjiro Yazawa, Takaaki Hikima, and Hiroyasu Masunaga


Benzyl ester group of amino acid monomers broadens the substrate specificity and enhance the affinity of papain in chemo-enzymatic copolymerization
Biomacromolecules,17(1):314-323 2015(Nov.)
Author:Jose M. Ageitos, Kenjiro Yazawa, Ayaka Tateishi, Kousuke Tsuchiya, Keiji Numata


Recent advances in chemoenzymatic peptide syntheses
Molecules,19(9):13755-13774 2014(Sep.)
Author:Kenjiro Yazawa and Keiji Numata


Real-time monitoring of intermediates reveals the reaction pathway in the thiol-disulfide exchange between disulfide bond formation protein A (DsbA) and B (DsbB) on a membrane-immobilized quartz-crystal microbalance (QCM) System
Journal of Biological Chemistr,288(50):35969-35981 2013(Dec.)
Author:Kenjiro Yazawa, Hiroyuki Furusawa, and Yoshio Okahata


Mechanism of thiol–disulfide exchange reactions between DsbA and DsbB over a wide pH range
Chemistry Letters,42(3):241-243 2013(Feb.)
Author:Kenjiro Yazawa, Hiroyuki Furusawa, and Yoshio Okahata


Spectrophotometric quantification of lactose in solution with a peroxidase-based enzymatic cascade reaction system
Analytical and Bioanalytical Chemistry,401:2307-2310 2011(Aug.)
Author:Sara Fornera, Kenjiro Yazawa, and Peter Walde

Research Grants
Grants‐in‐aid for Scientific Research(Research Representative)
2021 - 2023 , 未利用絹に含まれるフィブロインH鎖を用いた高強度な再生絹糸の創製 , 基盤研究(C)
2018 - 2020 , 熱成形可能な人工クモ糸シルクの合成 , 若手研究
2014 - 2015 , DNA修復酵素による傷害部位の効率的な認識機構の解明 , 若手研究(B)

Scholarship donation
2020 , ホクト生物科学振興財団 研究奨励金 融点を有する人工クモ糸シルクの創成

Education

Lectures
2022 , バイオファイバー科学
2022 , 繊維高分子化学
2022 , タンパク質工学
2022 , 応用生物科学科 新入生ゼミナール
2022 , バイオファイバー概論
2022 , 科学英語演習
2022 , 生物科学基礎実験
2022 , 応用生物科学ゼミナール
2022 , 応用生物科学実験III
2022 , 繊維状蛋白質特論
2022 , 卒業研究
2022 , 論文購読・プレゼンテーション演習
2022 , 生体高分子機能科学特論
2021 , バイオファイバー科学
2021 , 繊維高分子化学
2021 , タンパク質工学
2021 , 応用生物科学科 新入生ゼミナール
2021 , バイオファイバー概論
2021 , 繊維状蛋白質特論
2021 , 応用生物科学実験III
2021 , 卒業研究
2021 , 論文購読・プレゼンテーション演習
2020 , バイオファイバー科学
2020 , 繊維高分子化学
2020 , タンパク質工学
2020 , 応用生物科学科 新入生ゼミナール
2020 , 生物繊維資源学
2020 , 繊維状蛋白質特論
2020 , 応用生物科学実験III
2020 , 卒業研究
2020 , 論文購読・プレゼンテーション演習