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Yamazaki Masanori

Academic OrganizationAcademic Assembly School of Medicine and Health Sciences Institute of MedicineTEL
Education and Research OrganizationShinshu University School of Medicine Department of Medicine (Diabetes, Endocrinology and Metabolism)FAX
PositionAssociate ProfessorMail Address
AddressWeb site


Research Field
Current Subject
Immunogene therapy of endocrine tumors
Keywords:Endocrine oncology , immunology , gene therapy
Epidemiology of multiple endocrine neoplasia
Keywords:Multiple endocrine neoplasia
Epidemiology of type 2 diabetes
Keywords:Type 2 Diabetes


Books, Articles, etc.

Effects of Sitagliptin on Pancreatic Beta-Cells in Type 2 Diabetes With Sulfonylurea Treatment: A Prospective Randomized Study
J Clin Med Res,11(1):15-20 2019
Author:Sato A, Takei M, Hiramatsu K, Takeda T, Miyamoto T, Yamazaki M, Sato Y, Komatsu M

Implications of thyroid autoimmunity in infertile women with subclinical hypothyroidism in the absence of both goiter and anti-thyroid antibodies: lessons from three cases.
Endocr J,66(2):193-198 2019
Author:Oiwa A, Minemura K, Nishio SI, Yamazaki M, Komatsu M

Analysis for the Improvement of Inadequate Glycemic Control in Patients with Type 2 Diabetes Mellitus in Nagano, Japan
信州医学雑誌,66(5):319-324 2018(Oct.)
Author:Sato A, Sato Y, Kobayashi Y, Yamazaki M, Komatsu M

Prediction of lowest nocturnal blood glucose level based on self-monitoring of blood glucose in Japanese patients with type 2 diabetes
J Diabetes Complications,32(12):1118-1123 2018
Author:Sakurai K, Kawai Y, Yamazaki M, Komatsu M

Careful readings for a flash glucose monitoring system in nondiabetic Japanese subjects: individual differences and discrepancy in glucose concentrarion after glucose loading
Endocr J,64(8):827-832 2017
Author:Sekido K, Sekido T, Kaneko A, Hosokawa M, Sato A, Sato Y, Yamazaki M, Komatsu M

Early-onset, severe, and recurrent primary hyperparathyroidism associated with a novel CDC73 mutation.
Endocr J,62(7):627-632 2015
Author:Shibata Y, Yamazaki M, Takei M, Uchino S, Sakurai A, Komatsu M.

A newly identified missense mutation in RET codon 666 is associated with the development of medullary thyroid carcinoma.
Endocr J,61(11):1141-1144 2014
Author:Yamazaki M, Hanamura T, Ito K, Uchino S, Sakurai A, Komatsu M

Efficacy of combination therapy with sitagliptin and low-dose glimepiride in Japanese patients with type 2 diabetes
J Clin Med Res.,6:127-132 2014
Author:Ishii H, Ohkubo Y, Takei M, Nishio S, Yamazaki M, Kumagai M, Sato Y, Suzuki S, Aoki Y, Miyamoto T, Kakizawa T, Sakuma T, Komatsu M

Occurrence of IgG4-related hypophysitis lacking IgG4-bearing plasma cell infiltration during steroid therapy
Intern Med,53:753-757 2014
Author:Ohkubo Y, Sekido T, Takeshige K, Ishi H, Takei M, Nishio S, Yamazaki M, Komatsu M, Kawa S, Suzuki S.

Thymic neuroendocrine tumour in multiple endocrine neoplasia type 1: female patients are not rare exceptions.
Clin Endocrinol (Oxf).,78(2):248-54 2013
Author:Sakurai A, Imai T, Kikumori T, Horiuchi K, Okamoto T, Uchino S, Kosugi S, Suzuki S, Suyama K, Yamazaki M, Sato A; MEN Consortium of Japan.

糖尿病の家族歴が患者の疾患認識に及ぼす影響について : 糖尿病と遺伝の関係に関する患者の意識調査から
糖尿病,55(3):185-192 2012
Author:羽深 美恵子,櫻井 晃洋,山崎 雅則,駒津 光久,江口 尚,野見山 哲生,福嶋 義光

MEN1遺伝子に同定された塩基置換 変異か多型か?
日本内分泌学会雑誌,88 supple:90-94 2012
Author:櫻井 晃洋, 永村 優央子, 山崎 雅則, 島津 智子, 佐野 健司, 塚田 俊彦

糖尿病の家族歴が患者の疾患認識に及ぼす影響について 糖尿病と遺伝の関係に関する患者の意識調査から
糖尿病,55:185-192 2012
Author:羽深 美恵子, 櫻井 晃洋, 山崎 雅則, 駒津 光久, 江口 尚, 野見山 哲生, 福嶋 義光

Application of an intracellular stability test of a novel missense menin mutant to the diagnosis of multiple endocrine neoplasia type 1
Endocr J,59:1093-1098 2012
Author:Nagamura Y, Yamazaki M, Shimazu S, Tsukada T, Sakurai A.

Multiple endocrine neoplasia type 1 in Japan: establishment and analysis of a multicentre database
Clin Endocrinol (Oxf),76:533-539 2012
Author:Sakurai A, Suzuki S, Kosugi S, Okamoto T, Uchino S, Miya A, Imai T, Kaji H, Komoto I, Miura D, Yamada M, Uruno T, Horiuchi K, Miyauchi A, Imamura M; MEN Consortium of Japan, Fukushima T, Hanazaki K, Hirakawa S, Igarashi T, Iwatani T, Kammori M, Katabami T, Katai M, Kikumori T, Kiribayashi K, Koizumi S, Midorikawa S, Miyabe R, Munekage T, Ozawa A, Shimizu K, Sugitani I, Takeyama H, Yamazaki M.

Delay in the diagnosis of multiple endocrine neoplasia type 1: typical symptoms are frequently overlooked
Endocr J,59:797-807 2012
Author:Yamazaki M, Suzuki S, Kosugi S, Okamoto T, Uchino S, Miya A, Imai T, Kaji H, Komoto I, Miura D, Yamada M, Uruno T, Horiuchi K, Sato A, Miyauchi A, Imamura M, Sakurai A; MEN Consortium of Japan

Clinical features of insulinoma in patients with multiple endocrine neoplasia type 1: analysis of the database of the MEN Consortium ofJapan.
Encocr J,59:859-866 2012
Author:Sakurai A, Yamazaki M, Suzuki S, Fukushima T, Imai T, Kikumori T, Okamoto T, Horiuchi K, Uchino S, Kosugi S, Yamada M, Komoto I, Hanazaki K, Itoh M, Kondo T, Mihara M, Imamura M.

A Novel splice site mutation of the MEN1 gene indentified in a patient with primary hyperparathyroidism
Endocr J,59:523-530 2012
Author:Nagamura Y, Yamazaki M, Shimazu S, Sano K, Tsukada T, Sakurai A.

高齢者糖尿病治療の最前線】 Seminar 高齢者におけるGLP-1受容体作動薬の使い方
Geriatric Medicine,40:879-882 2011
Author:山崎 雅則, 駒津 光久

Distinct clinical courses in type 1 diabetes mellitus induced by peg-interferon-alpha treatment for chronic hepatitis C.
Intern Med.,49(5):403-7 2010
Author:Yamazaki M, Sato A, Takeda T, Komatsu M.

Transient polyuria related to central diabetes insipidus caused by lymphocytic infundibulo-neuro-hypophysitis in a patient treated for Graves' disease.
Intern Med,49(17):1885-1890 2010
Author:Yamazaki M, Sato A, Nishio S, Uehara T, Komatsu M

Cold-induced sweating syndrome with neonatal features of Crisponi syndrome: longitudinal observation of a patient homozygous for a CRLF1 mutation.
Am J Med Genet,A 152A:764-769 2010
Author:Yamazaki M, Kosho T, Kawachi S, Mikoshiba M, Takahashi J, Sano R, Oka K, Yoshida K, Watanabe T, Kato H, Komatsu M, Kawamura R,Wakui K, Knappskog PM, Boman H, Fukushima Y

Distinct Clinical Courses in Type 1 Diabetes Mellitus Induced by Peg-interferon-alpha Treatment for Chronic Hepatitis C
INTERNAL MEDICINE,49(5):403-407 2010
Author:Yamazaki, Masanori; Sato, Ai; Takeda, Teiji; Komatsu, Mitsuhisa

Spiking Expression of mu-Crystallin mRNA during Treatment with Methimazole in Patients with Graves'Hyperthyroidism
Author:Suzuki, S.; Takei, M.; Nishio, S.; Inaba, H.; Sato, A.; Yamazaki, M.; Shinomiya, K.; Hashizume, K.

Five cases of severe hyponatremia in the elderly successfully treated with low doses of hydrocortisone.
Geriatr Gerontol Int,9:391-394 2009
Author:Takei M, Suzuki S, Sato A, Yamazaki M, Shi S, Sato Y, Hashizume K

Acromegaly accompanied by Turner syndrome with 47,XXX/45,X/46,XX mosaicism
Intern Med,48(6):447-453 2009
Author:Yamazaki M, Sato A, Nishio S, Takeda T, Miyamoto T, Katai M, Hashizume K

日本老年医学会雑誌,45(2):145-148 2008
Author:橋爪 潔志,鈴木 悟,稲垣 毅,宮本 高秀,平松 邦英,小松 亜位,大岩 亜子,山崎 雅則,西尾 真一,稲葉 秀文,森 淳一郎,柿沢 供子,武田 貞二,重松 理

Biphasic function of focal adhesion kinase in endothelial tube formation induced by fibril-forming collagens
Biochem Biophys Res Commun,374:699-703 2008
Author:Nakamura J, Shigematsu S, Yamauchi K, Takeda T, Yamazaki M, Kakizawa T, Hashizume K

Beneficial effects of pioglitazone on cholangiohepatitis induced by bile duct carcinoma.
Intern Med,46:1723-1727 2007
Author:Suzuki S, Mori J, Yamazaki M, Sato A, Hosoda W, Hashizume K

ホルモンと臨牀,52(3):271-277 2004
Author:山崎 雅則,武田 貞二,橋爪 潔志

Adenovirus-mediated tumor-specificcombined gene therapy using herpes simplex virus thymidine/ganciclovir system and murine interleukin-12 induces effective antitumor activity against medullary thyroid carcinoma.
Cancer Gene Ther,11:8-15 2004
Author:Yamazaki M, Straus FH, Messina M, Robinson BG, Takeda T, Hashizume K, DeGroot LJ

Multiple endocrine neoplasia type 1 with unusual concomitance of various neoplastic disorders
ENDOCRINE JOURNAL,51(1):75-81 2004
Author:Nishimura, Y; Yamashita, K; Yumita, W; Yamazaki, M; Katai, M; Sakurai, A; Hashizume, K

Tumor-specific gene therapy for undifferentiated thyroid carcinoma utilizing the telomerase reverse transcriptase promotor.
J Clin Endocrinol Metab,88:3531-3538 2003
Author:Takeda T, Inaba H, Yamazaki M, Kyo S, Miyamoto T, Suzuki S, Ehara T, Kakizawa T, Hara M, DeGroot LJ, Hashizume K

A tandemly repeated thyroblobulin core promoter has potential to enhance efficacy for tissue-specific gene therapy for thyroid carcinomas.
Cancer Gene Ther,9:864-874 2002
Author:Takeda T, Yamazaki M, Minemura K, Imai Y, Inaba H, Suzuki S, Miyamoto T, Ichikawa K, Kakizawa T, Mori J, DeGroot LJ, Hashizume K

Effective gene therapy for medullary thyroid carcinoma using recombinant adenovirus inducing tumor-specific expression of interleukin-12.
Gene Ther,9:64-74 2002
Author:Yamazaki M, Zhang R, Straus FH, Messina M, Robinson BG, Hashizume K, DeGroot LJ

1,25-dihydroxyvitamin D-3 suppresses the expression of the VCAM-1 receptor, VLA-4 in human leukemic HL-60 cells
Author:Kaneko, A; Suzuki, S; Hara, M; Mori, J; Kumagai, M; Yajima, H; Yamashita, K; Kakizawa, T; Yamazaki, M; Takeda, T; Miyamoto, T; Ichikawa, K; Hashizume, K

Characterization of two novel retinoic acid-resistant cell lines derived from HL-60 cells following long-term culture with all-trans-retinoic acid
Author:Mori, J; Suzuki, S; Hara, M; Kaneko, A; Yamashita, K; Kumagai, M; Sakuma, T; Kakizawa, T; Yamazaki, M; Takeda, T; Miyamoto, T; Ichikawa, K; Hashizume,K

Progressive Albuminuria as a Key Factor Potentially Determining Cardiovascular Prognosis in the Elderly with Type 2 Diabetes: From a Three-Year Interim Report of a Cohort Study,Nagano Study 2
77th Amerian Diabetes Association Scientific Session 2019
Author:Yamazaki M, Shibata Y, Kawai Y, Komatsu M

Prediction of Lowest Nocturnal Blood Glucose (LNBG) Levels in Japanese Type 2 Diabetic (T2D) Patients Treated with Insulin
77th Amerian Diabetes Association Scientific Session 2017
Author:Kawai K, Yamazaki M, Sakurai K, komatsu K