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TOMIOKA Ikuo

Academic OrganizationAcademic Assembly School of Science and Technology Institute of AgricultureTEL
Education and Research OrganizationFaculty of Agriculture Department of Agricultural and Life SciencesFAX
PositionAssociate ProfessorMail Addresstomioka@@shinshu-u.ac.jp
Address8304, Minamiminowa-Village, Kamiina-County 399-4598Web site

Profile

Research Field
Reproductive biology
Reproductive technology
Nuerodegenerative disease
Keywords:Reproductive technology , Transgenic animal , Neurodegenerative disease , Reproductive endocrinology
Current Subject
Elucidation of the FXR function in the ovary and testis
Keywords:FXR , Knockout animal , CRISPR/Cas9
Production of Transgenic Marmoset for Neurodegenerative Disease Model
Keywords:Neurodegenerative disease , Marmoset , Transgenic
Academic Background
Degree
PhD. , Tohoku University

Research

Books, Articles, etc.
Articles
Optimization of piggyBac transposon-mediated gene transfer method in common marmoset embryos
PLOS ONE,18(6):e0287065. 2023
Author:Nanami Kohri,Mitsuo Ota,Hikaru Kousaku,Eiko N. Minakawa,Kazuhiko Seki,Ikuo Tomioka.


Genistein enhances NAD+ biosynthesis by upregulating nicotinamide phosphoribosyltransferase in adipocytes
J Nutr Biochem,28:109433 2023
Author:Watanabe S, Haruyama R, Umezawa K, Tomioka I, Nakamura S, Katayama S, Mitani T.


In vitro production of viable eggs from isolated mouse primary follicles by successive culture
Journal of Reproduction and Development,68(1):38-44 2022
Author:Tomohiro Kohama, Maika Masago, Ikuo Tomioka, Kanako Morohaku.


Generation of Common Marmoset Model Lines of Spinocerebellar Ataxia Type 3.
Front Neurosci,24(14):548002 2020
Author:Ikuo Tomioka, Yoshitaka Nagai, Kazuhiko Seki.


Evidence for involvement of FXR signaling in function of ovarian granulosa cells.
Journal of Reproduction and Development,8(65(1)):47-55 2019
Author:Takae K, Nakata M, Watanabe T, Sasada H, Fujii H, Tomioka I.


Highly efficient induction of primate iPS cells by combining RNA transfection and chemical compounds.
Genes to Cells 2019
Author:Toshiaki Watanabe, Shun Yamazaki, Nao Yoneda, Haruka Shinohara, Ikuo Tomioka, Yuichiro Higuchi, Mika Yagoto, Masatsugu Ema, Hiroshi Suemizu, Kenji Kawai, Erika Sasaki


Perspectives on developing biomarkers for neurodegenerative diseases using genetically-modified common marmoset models
Neural Regeneration Research 2018
Author:Ikuo Tomioka, Yoshitaka Nagai, Kazuhiko Seki


Generation of transgenic marmosets using a tetracyclin-inducible transgene expression system as a neurodegenerative disease model.
Biology of Reproduction,97(5):772-780 2017
Author:I Tomioka, N Nogami, T Nakatani, K Owari, N Fujita, H Motohashi, O Takayama, K Takae, Y Nagai, K Seki


Transgenic monkey model of the polyglutamine diseases recapitulating progressive neurological symptoms
eNeuro,4(2):e0250-16 2017
Author:Ikuo Tomioka, Hidetoshi Ishibashi, Eiko Minakawa, Hideyuki Motohashi, Osamu Takayama, Yuko Saito, H. Popiel, Sandra Puentes, Kensuke Owari, Terumi Nakatani, Naotake Nogami, Kazuhiro Yamamoto, Satoru Noguchi, Takahiro Yonekawa, Yoko Tanaka, Naoko Fujita, Hikaru Suzuki, Hisae Kikuchi, Shu Aizawa, Seiichi Nagano, Daisuke Yamada, Ichizo Nishino, Noritaka Ichinohe, Keiji Wada, Shinichi Kohsaka, Yoshitaka Nagai, and Kazuhiko Seki


非ヒト霊長類における発生工学の歴史
信州大学農学部紀要,52:9-15 2016
Author:富岡郁夫
Keywords:非ヒト霊長類, 発生工学, 実験動物, トランスジェニック, 標的遺伝子改変

Research Grants
Grants‐in‐aid for Scientific Research(Research Representative)
2023 - , 卵胞発育におけるFXRの機能解明と卵胞体外培養系への応用 , 基盤研究(B)