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Hidaka Hiroya|Shinshu University Researcher List

Hidaka Hiroya

School of Medicine Department of Health Sciences Clinical Laboratory Sciences 

Associate Professor 

Degree

  • 博士(医学), 信州大学

Research Keyword

    Clinical chemistry, Biochemsitry, Lipid

Field Of Study

  • Medical, Dental, and Pharmaceutical Science
  • Boundary Medicine
  • Others, Laboratory Medicine

Educational Background

  • 1977, Tokyo University of Pharmacy and Life Science, 薬学部
  • 1980, 静岡県立静岡薬科大学, Graduate School, Division of Pharmaceutical Sciences
Research activity information

Paper

  • Altered Serum Lysophosphatidylethanolamine Species Profile in Patients with Autoimmune Pancreatitis
    Yamaura Makoto, Hidaka Hiroya
    Shinshu Medical Journal, 70(2), 91-100, Apr. 2022リポジトリ電子ジャーナル
  • Consumption of Nonfat Milk Results in a Less Atherogenic Lipoprotein Profile: A Pilot Study
    Hidaka H, Takiwaki M, Yamashita M, Kawasaki K, Sugano M, Honda T. Hidaka H, Takiwaki M, Yamashita M, Kawasaki K, Sugano M, Honda T
    Ann Nutr Metab, 61(2), 111-116, 2012
  • Mild acid hydrolysis of sphingolipids yields lysosphingolipids: a matrix-assisted laser desorption and ionization time-of-flight mass spectrometry study
    Hidaka H, Takiwaki M, Yamashita M, Otsuki S, Kawasaki K, Sugano M, Honda T
    J Anal Bio-Sci, 35(3), 241-248, 2012
  • The Investigators of Study on Prevention of Metabolic Syndrome among Children, Adolescents, and YoungAdults in Shinshu: Association between serum uric acid levels and cardiometabolic risk factors among Japanese junior high school students.
    Hongo M, Hidaka H, Sakaguchi S, Nakanishi K, Ichikawa M, Hirota N, Tanaka N, Tsuruta G, Yazaki Y, Kinoshita O, Ikeda U, Koike K,
    Circ J, 74, 1570-1577, 2010
  • High-molecular-weight beta-amyloid oligomers are elevated in cerebrospinal fluid of Alzheimer patients.
    Fukumoto H, Tokuda T, Kasai T, Ishigami N, Hidaka H, Kondo M, Allsop D, Nakagawa M.
    FASEB J, 24(8), 2716-2726, 2010
  • 透析患者におけるホモシステインと透析療法の検討
    3. 塩澤 勉、中村啓章、田村克彦、長澤正樹、羽生 登、本田孝行、日高宏哉
    腎と透析, 69, 164-169, 2010
  • Characterization of cysteine and homocysteine bound to human serum transthyretin.
    Hanyu N, Shimizu T, Yamauchi K, Okumura N, Hidaka H.
    Clin Chim Acta., 403(1-2), 70-75, 2009
  • 一般中学生の高尿酸血症と生活習慣病との関連
    本郷 実、日高宏哉、阪口しげ子、市川元基、池田宇一、田中直樹、鶴田悟郎、小池健一,
    33, 17-26, 2009
  • Fluvastatin improves arterial stiffness in patients with coronary artery disease and hyperlipidemia: a 5-year follow-up study.
    Hongo M, Tsutsui H, Mawatari E, Hidaka H, Kumazaki S, Yazaki Y, Takahashi M, Kinoshita O, Ikeda U.
    Circ J., 72(5), 722-728, 2008
  • Specific, rapid, and sensitive enzymatic measurement of sphingomyelin, phosphatidylcholine and lysophosphatidylcholine in serum and lipid extracts.
    Hidaka H, Yamauchi K, Ohta H, Akamatsu T, Honda T, Katsuyama T.
    Clin Biochem., 41(14-15), 1211-1217, 2008
  • Analysis of human serum lipoprotein lipidcomposition using MALDI-TOF mass spectrometry.
    Hidaka H, Hanyu N, Sugano M, Kawasaki K, Yamauchi K, Katsuyama T.
    Ann Clin Lab Sci., 37(3), 213-221, 2007
  • Degradation of pre-beta-high density lipoproteins and their binding activity to human blood monocytes
    Nakabayashi T, Yamauchi K, Sugano M, Sano K, Tozuka M, Hidaka H
    Ann Clin Lab Sci, 34, 287-298, 2004
  • Purification and measurement of HDL3-binding proteins in human peripheral blood mononuclear cells
    Hidaka H, Tozuka M, Yamauchi K, Ohta H, Nakayama J, Katsuyama T
    Ann Clin Lab Sci, 33, 271-278, 2003
  • Purification and measurement of HDL3-binding proteins present in human peripheral monocytes.
    Hiroya Hidaka, Minoru Tozuka, Kazuyoshi Yamauchi, Hiroyoshi Ohta,Jun Nakayama, and Tsutomu Katsuyama
    Annals of clinical&laboratory science, 33(3), 2003
  • Characterization of an apolipoprotein E3 variant (Arg145->His) associated with mild hypertriglyceridemia.
    Hiroya Hidaka, Minoru Tozuka, Eiko Hidaka, Kazuyoshi Yamauchi, Hiroyoshi Ota ,Takayuki Honda, and Tsutomu Katsuyama
    Annals of clinical&laboratory science, 31(2), 163-170, 2003
  • Detection of monoclonal immunoglobulin by serum protein electrophoresis of samples from patient of Shinonoi General Hospital from 1992-2001
    Hanyu N, Kawaguchi K, Hshizume S, Shimizu T, Tozuka M, Fujita K, Hidaka H
    Jornal of Analytical Bio-Science, 26, 422-427, 2003
  • Characterization of triglyceride rich lipoproteins with very light density by ultracentrifugation and agarose gel electrophoresis using triglyceride- and cholesterol-staining
    Hiroya Hidaka, Minoru Tozuka, Barbara Meyer, Kazuyoshi Yamauchi, Mitsutoshi Sugano, Tetsuo Nakabayashi, and Tsutomu Katsuyama.
    Annals of clinical&laboratory science, 33(2), 167-178, 2003WebofScience
  • 自動生化学分析機を用いた免疫比濁法による血清および髄液中トランスサイレチンの測定
    笹野桂子、日高宏哉、菅野光俊、鈴木剛史、広仲英治、戸塚 実
    医学検査, 51(8), 1146-1149, 2002
  • 栄養アセスメント蛋白の測定法.-アルブ-ン,トランスフェリン,トランスサイレチン,レチノール結合蛋白-
    日高宏哉,戸塚 実
    検査と技術, 30, 1377-1382, 2002
  • Isoform-specific effect of apolipoprotein E on endocytosis of beta-amyloid in cultures of neuroblastoma cells.
    Kazuyoshi Yamauchi, Minoru Tozuka, Hiroya Hidaka,Tetsuo Nakabayashi , Mitsutoshi Sugano, and Tsutomu Katsuyama
    Annals of clinical&laboratory science, 32(1), 65-74, 2002WebofScience
  • Predominant apolipoprotein J exists as lipid-poor mixtures in cerebrospinal fluid
    Takefumi Suzuki,Minoru Tozuka, Kazuyoshi Yamauchi, Mitsutoshi Sugano, Testuo Nakabayashi, Nobuo Okumura, Hiroya Hidaka, Tshutomu Katsuyama
    Ann Clin Lab Sci, 32(4), 369-376, 2002WebofScience
  • Analysis of hemoglobin and globin chain variants by a commonly used capillary isoelctric focusing method
    Mitsutoshi Sugano, Hiroya Hidaka,Kazuyoshi Yamauchi, Tetsuo Nakabayashi,Yumiko Higuchi,Kiyotaka Fujita, Nobuo Okumura, Yoshihisa Ushiyama, Minoru Tozuka, and Tshutomu Katsuyama T.
    Electrophoresis, 21, 3016-3019, 2001
  • Confirmation of minor components of less polar neutral and acidic glycolipids in monkey brain tissue.
    Tamotsu Taketomi,Eiko Sugiyama, Kei-ichi Uemura, Atsushi Hara, Hiroya Hidaka, Minoru Tozuka,Tetsuo Nakabayashi, and Tsutomu Katsuyama.
    Journal of Lipid Research, 42, 873-885, 2001
  • リポ蛋白分画中の脂質組成の分析
    日高宏哉、山内一由、戸塚 実
    検査と技術, 29(9), 1053-1059, 2001
  • Size-related and size-unrelated functional heterogeneity among pancreatic islets
    Toru Aizawa, Tsuyoshi Kaneko, Keishi Yamauchi, Hiroki Yajima, Tomoko Nishizawa, Toshihiko Yada, Hiroshi Matsukawa, Minoru Nagai, Satoko Yamada, Yoshihiko Sato, Mitsuhisa Komatsu, Nobuo Itoh, Hiroya Hidaka, Yoshitaka Kajimoto and Kiyoshi Hashizume
    Life Science, 69, 2627-2639, 2001
  • LDアイソザイムの測定
    羽生 登、清水敏夫、日高宏哉
    検査と技術, 29(12), 1329-1336, 2001
  • 過去5年間、血清蛋白電気泳動法により検出されたM蛋白の集計
    羽生 登、橋詰幸子、田中順子、永井久美子、清水敏夫、戸塚 実、日高宏哉
    医学検査, 50(8), 1037-1041, 2001
  • 酵素法による液状カルシウム測定試薬「ダイヤカラー・リキッドCa」の基礎的検討
    菅野光俊、日高宏哉、鈴木剛史、笹野桂子、広仲英治、野本昭三、戸塚 実
    現代医療., 33, 134-138, 2001
  • Characterization of an apolipoprotein E3 variant (Arg 145 ->His) associated with mild hypertriglyceridemia
    Hidaka, H; Tozuka, M; Hidaka, E; Yamauchi, K; Ota, H; Honda, T; Katsuyama, T
    ANNALS OF CLINICAL AND LABORATORY SCIENCE, 31(2), 163-170, 2001WebofScience
  • Helicobacter pylori and two ultrastructurally distinct layers of gastric mucous cell mucins in the surface mucous gel layer
    Eiko Hidaka, Hiroyoshi Ota, Hiroya Hidaka, Masayoshi Hayama, Taiji Akamatsu, Jun Nakayama and Tsutomu Katsuyama
    Gut., 49(4), 474-480, 2001WebofScience
  • Evaluation of the automatic fluorescent image analyzer,Image Titer, for quantitative analysis of antinuclear antibodies
    Tetsuo Nakabayashi, Toshiko Kumagai, Kazuyoshi Yamauchi, Mitsutoshi Sugano, Kiyptaka Fujita, Hiroya Hidaka, Minoru Tozuka
    Journal of Clin Pathology, 115(3), 424-429, 2001WebofScience
  • Cell Lineage Specificity of Newly Raised Monoclonal Antibodies Against Gastric Mucins in Normal, Metaplastic and Neoplastic Human Tissues and Their Application for Pathology Diagnosis.
    Hiroyoshi Ota, Masayoshi Hayama, Jun Nakayama, Hiroya Hidaka, Takayuki Honda, Keiko Ishii, Mana Fukushima, Takeshi Uehara, Makoto Kurihara, Kazuhiko Ishihara, Kyoko Hotta, Tsutomu Katsuyama
    AMERICAN JOURNAL OF CLINICAL PATHOLOGY, 115(1), 69-79, 2001WebofScience
  • Relation of Helicobacter pylori to mucins and mucouscells in human stomach.
    Eiko Hidaka, Hiroyashi Ota, Masayoshi Hayama, Hiroya Hidaka, Keiko Ishii, Kosei Nakajima, Akihiko Yoshizawa, Tsutomu Katsuyama
    Journal of Cell Molecular Medicine, 4(3), 224-225, 2000
  • 合成基質を用いた液状リパ-ゼ測定試薬の検討
    菅野光俊、山内一由、広仲英治、中林徹雄、日高宏哉、戸塚 実
    医学検査, 49, 1608-1611, 2000
  • イムノクロマトグラフィー法による感染症簡易検出キットの緊急検査適用についての検討-HBs抗原、HBs抗体およびTP抗体検出キットについて
    浜 尚枝、中林徹雄,熊谷俊子、日高宏哉,戸塚 実
    医学検査, 49(2), 150-154, 2000
  • Effect of apolipoprotein AII on the interaction of apolipoprotein E with beta-amyloid: some apo(E-AII) complexes inhibit the internalization of beta-amyloid in cultures of neuroblastoma cells.
    Kazuyoshi Yamauchi, Minoru Tozuka, Hiroya Hidaka, Tetsuo Nakabayashi, Mitsutoshi Sugano, KondoYoshiyuki, Akira Nakagawara, and Tshutomu Katsuyama
    Journal of Neuroscience Research, 62(4), 608-614, 2000WebofScience
  • Coexistence of gland mucous cell-type mucin and lysozyme in gastric gland mucous cells
    Eiko Hidaka, Hiroyoshi Ota, Tsutomu Katsuyama, Jun Nakayama , Masanobu Momose, Hiroya Hidaka, Keiko Ishii, Fusayoshi Murata, Shinichiro Tsuyama, Makoto Kurihata, Kazuhiko Ishihara, Kyoko Hotta
    Histochem Biol Cell, 113(2), 91-98, 2000WebofScience
  • The identification of specific high density lipoprotein3 binding sites on human blood monocytes using fluorescence-labeled ligand.
    Hiroya Hidaka, Eiko Hidaka,Minoru Tozuka,Jun Nakayama, Tsutomu Katsuyama, and Noel Fidge
    Journal of Lipid Research, 40(6), 1131-1139, 1999WebofScience
  • Characterization of apolipoprotein E-containing lipoproteins in cerebrospinal fluid: eddect of phenotype on the distribution of apolipoprotein E
    Kazuyoshi Yamauchi, Minoru Tozuka, Hiroya Hidaka, Eiko Hidaka, Yoshiyuki Kondo, and Tsutomu Katsuyama
    CLINICAL CHEMISTRY, 45(9), 1431-1438, 1999WebofScience
  • Higher avidity binding of apolipoprotein (E-AII) complex than of apolipoprotein E monomer to beta-amyloid
    Kazuyoshi Yamauchi, Minoru Tozuka, Tetsuo Nakabayashi, Mitsutoshi Sugano, Hiroya Hidaka, Yoshiyuki Kondo, Tsutomu Katsuyama
    JOURNAL OF NEUROSCIENCE RESEARCH, 58(2), 301-307, 1999WebofScience
  • Genetic analyses in homozygous and heterozygous variants of lactate dehydrogenase-B(H) subunit-LD-B Matsumoto I and II (LD-B W323R)
    Nobuo Okumura, Fumiko Terasawa, Ichiro Ueno, Keiko Oki, Kazuyoshi Yamauchi, Hiroya Hidaka, Minoru Tozuka, Mitsue Okura, Tsutomu Katsuyama
    Clinical Chimica Acta, 287(1-2), 163-171, 1999WebofScience

Affiliated academic society

  • Japanese Society of Laboratory Medicine
  • Japabese Association of Medical Technology
  • Japan Atherosclerosis Society
  • The Society of Analytical Bio-Science
  • Japan Society of Clinical Chemistry

Research Themes

  • The elucidation of the mechanism of lipidosis
    2003
  • Adipose intestinal absorption and metabolism
    2003
  • Analysis of HDL-binding proteins
    2003
  • Young life-style related diseases prevention and education
    2003
  • Quality management of clinical laboratory tests
    2003
  • Laboratory assessment of nutrition management
    2003
  • Analysis of phospholipid by mass spectrometry
    1995
  • Denaturation of the apolipoprotein
    1995
  • Analysis and metabolism of high density lipoprotein (HDL)
    1989
  • 炎症性腸管疾患の脂質及びアポ蛋白代謝機序と質量分析による病態指標検査法の開発
    科学研究費補助金, 基盤研究(C)
  • 炎症性腸管疾患の血清脂質とアポ蛋白の代謝機序を解明するための質量分析法の開発
    科学研究費補助金, 萌芽研究