MORI MASAYUKI
Academic Assembly School of Medicine and Health Sciences Institute of Medicine
Interdisciplinary Cluster for Cutting Edge Research Institute for Biomedical Sciences
AssociateProfessor
Researcher Information
Research activity information
Paper
- Renal function in aged C57BL/6J mice is impaired by deposition of age-related apolipoprotein A-II amyloid independent of kidney aging
Li Y., Dai J., Kametani F., Yazaki M., Ishigami A., Mori M., Higuchi K., Miyahara H.
Am. J. Pathol., 93, 725-739, 2023, Refereed - Macrophages in the reticuloendothelial system inhibit early induction stages of mouse apolipoprotein A-II amyloidosis
Miyahara H., Dai J., Li Y., Cui X., Takeuchi H., Hachiya N., Kametani F., Yazaki M., Mori M., Higuchi K.
Amyloid, 30, 225-238, 2023, Refereed - Cyba and Nox2 mutant rats show different incidences of eosinophilia in the genetic background- and sex-dependent manner
Mori M., Dai J., Miyahara H., Li Y., Kang X., Yoshimi K., Mashimo T., Higuchi K., Matsumoto K.
Experimental Animals, 72, 233-241, 2023, Refereed
Lead, Corresponding - BALB.NCT-Cpoxnct is a unique mouse model of hereditary coproporphyria
Kang X., Shimada S., Miyahara H., Higuchi H., Mori M.
Mol. Genet. Metab. Rep., 35, 100964, 2023
Corresponding - Polygenic control of the wavy coat of the NCT mouse: involvement of an intracisternal A particle insertional mutation of the protease, serine 53 (Prss53) gene, and a modifier gene
Mori M., Liu C., Yoshizawa T., Miyahara H., Dai J., Igarashi Y., Cui X., Li Y., Kang X., Higuchi K.
Mammalian Genome, 33, 451-464, 2022, Refereed, Not invited
Lead, Corresponding - Curcumin promotes AApoAII amyloidosis and peroxisome proliferation in mice by activating the PPARα signaling pathway
Dai J., Li Y., Kametani F., Cui X., Igarashi Y., Huo J., Miyahara H., Mori M., Higuchi K.
Elife, 10, e63538, 2021, Refereed - Glavonoid-rich oil supplementation reduces stearoyl-coenzyme A desaturase 1 expression and improves systemic metabolism in diabetic, obese KK-Ay mice
Igarashi Y., Iida S., Dai J., Huo J., Cui X., Sawashita J., Mori M., Miyahara H., Higuchi K.
Biomed. Pharmacother., 140, 111714, 2021, Refereed, Not invited - Comprehensive proteomic profiles of mouse AApoAII amyloid fibrils provide insights into the involvement of lipoproteins in the pathology of amyloidosis
Miyahara H., Sawashita J., Ishikawa E., Yang M., Ding X., Liu Y., Hachiya N., Kametani F., Yazaki M., Mori M., Higuchi K.
J. Proteomics, 172, 111-121, 2018, Refereed - Extracellular deposition of mouse senile AApoAII amyloid fibrils induced different unfolded protein responses in the liver, kidney and heart
Luo H., Sawashita J., Tian G., Liu Y., Li L., Ding X., Xu Z., Yang M., Miyahara H., Mori M., Qian J., Wang Y., Higuchi K.
Lab. Invest., 95(3), 320-333, 2015, Refereed - The factors affecting adherence to a long-term interval walking training program in middle-aged and older people
Masuki S., Mori M., Tabara Y., Sakurai A., Hashimoto S., Morikawa M., Miyagawa K., Sumiyoshi E., Miki T., Higuchi K., Nose H., Shinshu University Genetic Research Consortium
J. Appl. Physiol., 118(5), 595-603, 2015, Refereed - Ubiquinol-10 supplementation activates mitochondria functions to decelerate senescence in senescence accelerated mice.
Tian G., Sawashita J., Kubo H., Nishio S., Hashimoto S., Suzuki N., Yoshimura G., Tsuruoka M., Wang Y., Liu Y., Luo H., Xu Z., Mori M., Kitano M., Hosoe K., Takeda T., Usami S., Higuchi K.
Antioxid. Redox Signal., 20(16), 2606-2620, 2014, Refereed - Specific mtDNA Mutations in Mouse Carcinoma Cells Suppress Their Tumor Formation via Activation of the Host Innate Immune System
Imanishi, H; Takibuchi, G; Kobayashi, T; Ishikawa, K; Nakada, K; Mori, M; Kikkawa, Y; Takenaga, K; Toyama-Sorimachi, N; Hayashi, JI
PLOS ONE, 8(9), UNSP e75981, 2013, Refereed - Exome sequencing of senescence-accelerated mice (SAM) reveals deleterious mutations in degenerative disease-causing genes
Tanisawa, K; Mikami, E; Fuku, N; Honda, Y; Honda, S; Ohsawa, I; Ito, M; Endo, S; Ihara, K; Ohno, K; Kishimoto, Y; Ishigami, A; Maruyama, N; Sawabe, M; Iseki, H; Okazaki, Y; Hasegawa-Ishii, S; Takei, S; Shimada, A; Hosokawa, M; Mori, M; Higuchi, K; Takeda, T; Higuchi, M; Tanaka, M
BMC GENOMICS, 14, 248, 2013, Refereed - Nuclear but Not Mitochondrial DNA Involvement in Respiratory Complex I Defects Found in Senescence-Accelerated Mouse Strain, SAMP8
IMANISHI Hirotake,YOKOTA Mutsumi,MORI Masayuki,SHIMIZU Akinori,NAKADA Kazuto,HAYASHI Jun-Ichi
EXPERIMENTAL ANIMALS, 60(4), 397-404, 2011, Refereed - ApoA-I deficiency in mice is associated with redistribution of apoA-II and aggravated AApoAII amyloidosis
Wang Yaoyong, Sawashita Jinko, Qian Jinze, Zhang Beiru, Fu Xiaying, Tian Geng, Chen Lei, Mori Masayuki, Higuchi Keiichi
Journal of Lipid Research, 52(8), 1461-1470, 2011, Refereed - Supplementation with the reduced form of Coenzyme Q10 decelerates phenotypic characteristics of senescence and induces a PPAR-α gene expression signature in SAMP1 mice
Schmelzer Constance, Kubo Hiroshi, Mori Masayuki, Sawashita Jinko, Kitano Mitsuaki, Hosoe Kazunori, Boomgaarden Inka, Döring Frank, Higuchi Keiichi
Molecular Nutrition&Food Research, 54(6), 805-815, 2010, Refereed - Mouse model to study human Aβ2M amyloidosis: Generation of a transgenic mouse with excessive expression of human β2-microglobulin
Zhang Pengyao, Fu Xiaying, Sawashita Jinko, Yao Junjie, Zhang Beiru, Qian Jinze, Tomozawa Hiroshi, Mori Masayuki, Ando Yukio, Naiki Hironobu, Higuchi Keiichi
Amyloid, 17(2), 50-62, 2010, Refereed - The reduced form of Coenzyme Q10 mediates distinct effects on cholesterol metabolism at the transcriptional and metabolite level in SAMP1 mice
Schmelzer Constance, Okun Jürgen G., Haas Dorothea, Higuchi Keiichi, Sawashita Jinko, Mori Masayuki, Döring Frank
IUBMB Life, 62(11), 812-818, 2010, Refereed - Eosinophilia in the MES rat strain is caused by a loss-of-function mutation in the gene for cytochrome b(-245), alpha polypeptide (Cyba)
Mori, M., Li, G., Hashimoto, M., Nishio, A., Tomozawa, H., Suzuki, N., Usami, S., Higuchi, K., Matsumoto, K.
J. Leukoc. Biol., 86(3), 473-478, 2009
Lead, Corresponding - Characterization of the cheetah serum amyloid A1 gene: critical role and functional polymorphism of a cis-acting element
Zhang, B., Une, Y., Ge, F., Fu, X., Qian, J., Zhang, P., Sawashita, J., Higuchi, K., Mori, M.
J. Hered., 99, 355-363, 2008, Invited
Corresponding - Fecal transmission of AA amyloidosis in the cheetah contributes to high incidence of disease
Zhang, B., Une, Y., Fu, X., Ge, F., Ya,o J., Sawashita, J., Mori, M., Tomozawa, H., Kametani, F., Higuchi, K.
Proc. Natl. Acad. Sci. USA., 105, 7263-7268, 2008, Refereed - Senescence-Accelerated Mouse (SAM) strains have a spontaneous mutation in the Abcb1a gene
Zhang, G., Zhang, B., Fu, X., Tomozawa, H., Matsumoto, K., Higuchi, K., Mori, M.
EXPERIMENTAL ANIMALS, 57, 413-417, 2008, Refereed
Corresponding - Quantitative trait locus that determines the cross-sectional shape of the femur in SAMP6 and SAMP2 mice
Otsuki, B., Matsumura, T., Shimizu, M., Mori, M., Okudaira, S., Nakanishi, R., Higuchi, K., Hosokawa, M., Tsuboyama, T., Nakamura, T.
J. Bone Miner. Res., 22(5), 675-685, 2007, Refereed - Amyloidosis in transgenic mice expressing murine amyloidogenic apolipoprotein (Apoa2c)
Ge, F., Yao, J., Fu, X., Guo, Z., Yan, J., Zhang, B., Zhang, H., Tomozawa, H., Miyazaki, J., Sawashita, J., Mori, M., Higuchi, K.
Lab. Invest., 87, 633-643, 2007, Refereed - Cross-seeding and cross-competition in mouse apolipoprotein A-II amyloid fibrils (AApoAII) and protein A amyloid fibrils (AA)
Yan, J., Fu, X., Ge, F., Zhang, B., Yao, J., Zhang, H., Qian, J., Tomozawa, H., Naiki, H., Sawashita, J., Mori, M., Higuchi, K.
Am. J. Pathol., 171, 172-180, 2007, Refereed - Functional polymorphisms of the Lss and Fdft1 genes in laboratory rats
Mori, M., Sawashita, J., Higuchi, K.
EXPERIMENTAL ANIMALS, 56, 93-101, 2007, Refereed
Lead, Corresponding - Secreted Frizzled-Related Protein 4 is a negative regulator of peak BMD in SAMP6 mice
Nakanishi, R., Shimizu, M., Mori, M., Akiyama, H., Otsuki, B., Okudaira, S., Hashimoto, M., Higuchi, K., Tsuboyama, T., Nakamura, T
J. Bone Mineral Res., 21, 1713-1721, 2006, Refereed - Transmissibility of mouse AApoAII amyloid fibrils: inactivation by physical and chemical methods
Zhang H., Sawashita J., Fu X., Korenaga T., Yan J., Mori M., Higuchi K.
FASEB JOURNAL, 20(7), 1012-1014, 2006, Refereed - Lanosterol synthase mutations cause cholesterol deficiency-associated cataracts in the Shumiya cataract rat
Mori M., Li G., Abe I., Nakayama J., Guo Z., Sawashita J., Ugawa T., Nishizono S., Serikawa T., Higuchi K., Shumiya S.
JOURNAL OF CLINICAL INVESTIGATION, 116(2), 395-404, 2006, Refereed
Lead, Corresponding - Tissue distribution, biochemical properties, and transmission of mouse type A AApoAII amyloid fibrils
Korenaga T., Fu X., Xing Y., Matsusita T., Kuramoto K., Shumiya S., Hasegawa K., Naiki H., Ueno M., Ishihara T., Hosokawa M., Mori M., Higuchi K.
AMERICAN JOURNAL OF PATHOLOGY, 164(5), 1597-1606, 2004, Refereed - 多因子遺伝性疾患モデルとしての白内障ラットの解析
森 政之
信州医学雑誌, 51(2), 105-106, 2003, Refereed
Lead, Corresponding - 遺伝的解析のモデル生物、マウス
森 政之, 芹川忠夫
遺伝子医学別冊「これだけは知っておきたい遺伝子医学の基礎知識」, 154-158, 2003
Lead - 老化疾患モデル ーマウス
森 政之, 樋口京一
現代医療, 34(2), 37-42, 2002
Lead, Corresponding - 老化疾患モデルマウス
森 政之, 樋口京一
Molecular Medicine, 39(5), 528-533, 2002 - Chediak-Higashi症候群とベージュミュータント動物
森 政之
別冊・医学のあゆみ 免疫疾患-state of arts ver. 2, 303-306, 2002
Lead, Corresponding - 老化促進マウス(SAM)の解析
樋口京一, 森 政之
BIO Clinica, 16(9), 57-61, 2001 - Extra-hepatic expression of apolipoprotein A-II in mouse tissues: Possible contribution to mouse senile amyloidosis
L. Fu, I. Matsuyama, T. Chiba, Y. Xing, T. Korenaga, Z. Guo, J. Nakayama, M. Mori, K. Higuchi
Journal of Histochemitry and Cytochemistry, 49(6), 739-748, 2001, Refereed - マウスを用いた老化・寿命の分子遺伝学的研究
森 政之, 樋口京一
基礎老化研究, 25(2), 77-82, 2001
Lead, Corresponding - Spontaneous Loss-of-Function Mutations of the 8-Oxoguanine DNA Glycosylase Gene in Mice and Exploration of the Possible Implication of the Gene in Senescence
M. Mori, S. Toyokuni, S. Kondo, H. Kasai, H. Naiki, E. Toichi , M. Hosokawa, K. Higuchi
Free Radical Biology&Medicine, 30(10), 1130-1136, 2001, Refereed
Lead, Corresponding - ApoA-II gene does not rescue Senescence-Accelerated Mouse (SAMP1) from short life span and accelerated mortality
Wang J., Matsushita T., Kogishi K., Xia C., Ohta A., Chiba T., Nakamura A., Kondoh H., Mori M., Hosokawa M., Higuchi K.
Journal of Gerontology. B Biological Science, 55A(9), B432-B439, 2000, Refereed - Wild type ApoA-II gene does not rescue senescence-accelerated mouse (SAMP1) from short life span and accelerated mortality
Wang, J; Matsushita, T; Kogishi, K; Xia, C; Ohta, A; Chiba, T; Nakamura, A; Kondo, H; Mori,M; Hosokawa, M; Higuchi, K
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES, 55(9), B432-B439, 2000, Refereed - わが国が貢献したマウスラットの疾患遺伝子の情報
森 政之, 西村正彦, 西川 哲
アニテックス, 10(2), 25-29, 1998
Lead, Corresponding - Genetic profile of the SMXA recombinant inbred mouse strains revealed with restriction landmark genomic scanning
Mori M., Akiyoshi S., Mizuno Y., Okuizumi H., Okazaki Y., Hayashizaki Y., Nishimura M
MAMMALIAN GENOME, 9(9), 695-709, 1998, Refereed
Lead, Corresponding
Books and other publications
- Biophysical Inquiry into Protein Aggregation and Amyloid Diseases
Higuchi, K., Fu, X., Zhang, B., Sawashita J, Mori, M., Joint work, Genetics and transmission of mouse systemic amyloidosis
Research SignPost, 253-267 2008XIth International Symposium on Amyloidosis
Fu, X., Korenaga, T., Yan, J., Ge, F., Zhan, B., Qian, J., Naiki, H., Sawashita, J., Mori, M., Higuchi, K., Joint work, Mouse senile amyloidosis: possible horizontal transmission in the mouse room
CRC Press, 10-12 2007XIth International Symposium on Amyloidosis
Higuchi, K., Ge, F., Fu, X., Yao, J., Zhan, B., Zhan, H., Qian, J., Sawashita, J., Mori, M., Joint work, Amyloidosis in the transgenic mice of mouse amyloidgenic apolipoprotein A-II (Apoa2C)
CRC Press, 143-145 2007Transmission of Mouse AApoAII Amyloidosis by the Amyloid Fibrils; Inhibitory Effects on Transmission by the Denaturation/Degradation of Amyloid FibrilsGrateau G, Kyle RA, Skinner M eds: Amyloid and Amyloidosis
Sawashita J, Zhang H, Fu X, Korenaga T, Mori M, Higuchi K, Joint work
CRC Press, Boca Raton, pp 457-459 2005Transmission of Mouse AApoAII Amyloidosis from Mother to Pups. Grateau G, Kyle RA, Skinner eds: Amyloid and Amyloidosis
Korenaga T, Fu X, Mori M, Sawashita J, Naiki H, Matsushita T, Higuchi K, Joint work
CRC Press, Boca Raton,, pp 457-459 2005Nomura Y, Takeda T, Okuma Y ed.: The Senescence-Accelerated Mouse(SAM): An animal model of senescence
Higuchi K, Xing Y, Fu X, Korenaga T, Guo Z, Nakamura A, Mori M, Joint work, Mouse senile amyloidosis in the SAM model
Elsevier, Amsterdam, pp 35-40 2004Nomura Y, Takeda T, Okuma Y ed.: The Senescence-Accelerated Mouse(SAM): An animal model of senescence
Mori M, Higuchi K, Joint work, Genetic monitoring system for SAM strains utilizing DNA markers
Elsevier, Amsterdam, pp 187-190 2004Nomura Y, Takeda T, Okuma Y ed.: The Senescence-Accelerated Mouse(SAM): An animal model of senescence
Fu X, Korenaga T, Xing Y, Fu L, Guo Z, Matsushita T, Hosokawa M, Naiki H, Mori M, Higuchi K, Joint work, Induction of AApoAⅡ and AA amyloidosis by the injection of various amyloid fibrils
Elsevier, Amsterdam, pp 383-386 2004