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Academic OrganizationAcademic Assembly School of Medicine and Health Sciences Institute of MedicineTEL
Education and Research OrganizationSchool of Medicine Department of Surgery Division of Gastroenterological, Hepato-Biliary-Pancreatic, Transplantation and Pediatric SurgeryFAX
PositionAssociate ProfessorMail Address
Address3-1-1 Asahi, Matsumoto, Nagano 390-8621Web site


Research Career
Research Career
2015- , Lecturer
2007- , Assistant professor


Books, Articles, etc.
Safety and Oncological Benefit of Hepatopancreatoduodenectomy for Advanced Extrahepatic Cholangiocarcinoma with Horizontal Tumor Spread: Shinshu University Experience
ANNALS OF SURGICAL ONCOLOGY,28(4):2012-2025 2021(Apr.)
Author:Shimizu, Akira; Motoyama, Hiroaki; Kubota, Koji; Notake, Tsuyoshi; Fukushima, Kentaro; Ikehara, Tomohiko; Hayashi, Hikaru; Yasukawa, Koya; Kobayashi, Akira; Soejima, Yuji;

Treatment Strategy for Pancreatic Neuroendocrine Neoplasms (pNEN)
信州医学雑誌,68(5):235-242 2020(Oct. 10)
Author:Kubota, Koji; Shimizu, Akira; Notake, Tsuyoshi; Sugenoya, Shinsuke; Hosoda, Kiyotaka; Yasukawa, Koya; Hayashi, Hikaru; Kobayashi, Ryoichiro; Soejima, Yuji

Correlation of clinicopathological features and leucine-rich repeat-containing G-protein-coupled receptor 5 expression in pancreatic ductal adenocarcinoma.
Pathol Res Pract.,215(11):152623 2019(Nov.)
Author:Kuraishi Y, Uehara T, Kobayashi Y, Nakajima T, Watanabe T, Shimizu A, Ota H, Tanaka E.

Impact of age on groin hernia profiles observed during laparoscopic transabdominal preperitoneal hernia repair.
Surg Endosc.,33(8):2602-2611 2019(Aug.)
Author:Fukushima K, Yokoyama T, Miwa S, Motoyama H, Arai T, Kitagawa N, Shimizu A, Notake T, Kikuchi T, Kobayashi A, Miyagawa SI.

Treatment with specific soluble factors promotes the functional maturation of transcription factor-mediated, pancreatic transdifferentiated cells.
PLoS One.,13(5):e0197175 2018(May)
Author:Motoyama H, Kobayashi A, Yokoyama T, Shimizu A, Sakai H, Notake T, Fukushima K, Miyagawa SI.

Nomogram predicting long-term survival after the diagnosis of intrahepatic recurrence of hepatocellular carcinoma following an initial liver resection.
Int J Clin Oncol,22(4):715-725 2017(Aug.)
Author:Notake T, Kobayashi A, Shinkawa H, Kawahara T, Shimizu A, Yokoyama T, Hasegawa K, Kokudo N, Matsuyama Y, Makuuchi M, Miyagawa SI.

Survival Benefits of Surgical Resection in Patients with Recurrent Biliary Tract Carcinoma.
World J Surg,:in press 2017(Jul.)
Author:Motoyama H, Kobayashi A, Yokoyama T, Shimizu A, Kitagawa N, Notake T, Fukushima K, Masuo H, Yoshizawa T, Miyagawa SI.

Adjuvant Chemotherapy with Gemcitabine for Resected Biliary Tract Cancer: A Single-Arm Phase 2 Study
信州医学雑誌,65(2):99-111 2017(Apr. 10)
Author:Kitagawa, Noriyuki; Motoyama, Hiroaki; Kobayashi, Akira; Yokoyama, Takahide; Shimizu, Akira; Notake, Tsuyoshi; Fukushima, Kentaro; Masuo, Hitoshi; Yoshizawa, Takahiro; Tsukahara, Teruomi; Miyagawa, Shin-ichi

Correlation between the serum levels of type IV collagen 7s domain and the risk of intractable ascites following liver resection for hepatocellular carcinoma: A propensity score-matched analysis.
Surgery,160(5):1244-1255 2016(Nov.)
Author:Shimizu A, Kobayashi A, Yokoyama T, Motoyama H, Sakai H, Kitagawa N, Notake T, Shirota T, Fukushima K, Miyagawa SI.

Neuroendocrine tumor of the common bile duct.
Surgery,160(2):525-6 2016(Aug.)
Author:Hosoda K, Kobayashi A, Shimizu A, Kitagawa N, Ito T, Yamada A, Miyagawa S.

Contrast-enhancement ratio on multiphase enhanced computed tomography predicts recurrence of pancreatic neuroendocrine tumor after curative resection.
Pancreatology,16(3):397-402 2016(May)
Author:Arai T, Kobayashi A, Fujinaga Y, Yokoyama T, Shimizu A, Motoyama H, Kitagawa N, Notake T, Shirota T, Fukushima K, Masuo H, Kadoya M, Miyagawa S.

Features of acute liver congestion on gadoxetate disodium-enhanced MRI in a rat model: Role of organic anion-transporting polypeptide 1A1
Author:Shimizu, Akira; Kobayashi, Akira; Motoyama, Hiroaki; Sakai, Hiroshi; Yamada, Akira; Yoshizawa, Akihiko; Momose, Masanobu; Kadoya, Masumi; Miyagawa, Shin-ichi;

Biliary tract variations of the left liver with special reference to the left medial sectional bile duct in 500 patients
AMERICAN JOURNAL OF SURGERY,210(2):351-356 2015(Aug.)
Author:Furusawa, Norihiko; Kobayashi, Akira; Yokoyama, Takahide; Shimizu, Akira; Motoyama, Hiroaki; Kanai, Keita; Arakura, Norikazu; Yamada, Akira; Kitou, Yoshihiro; Miyagawa, Shin-ichi;

Effect of Application of Subcutaneous Suction Drainage with Subcuticular Sutures for Wound Closure on the Incidence of Incisional Surgical Site Infection following Elective General Abdominal Surgery : A Randomized Controlled Trial
信州医学雑誌,63(2):91-101 2015(Apr. 10)
Author:SHIMIZU, Akira; KOBAYASHI, Akira; KOIDE, Naohiko; SUZUKI, Akira; TAKEUCHI, Daisuke; YOKOYAMA, Takahide; MOTOYAMA, Hiroaki; FURUSAWA, Norihiko; TSUKAHARA, Teruomi; MIYAGAWA, Shin-ichi

Impact of advanced age on the short- and long-term outcomes in patients undergoing hepatectomy for hepatocellular carcinoma: a single-center analysis over a 20-year period
AMERICAN JOURNAL OF SURGERY,209(4):733-741 2015(Apr.)
Author:Motoyama, Hiroaki; Kobayashi, Akira; Yokoyama, Takahide; Shimizu, Akira; Sakai, Hiroshi; Furusawa, Norihiko; Notake, Tsuyoshi; Kitagawa, Noriyuki; Arai, Takuma; Yokoi, Kenta; Okubo, Yohei; Miyagawa, Shin-ichi;

Liver failure after hepatocellular carcinoma surgery
LANGENBECKS ARCHIVES OF SURGERY,399(8):1047-1055 2014(Dec.)
Author:Motoyama, Hiroaki; Kobayashi, Akira; Yokoyama, Takahide; Shimizu, Akira; Furusawa, Norihiko; Sakai, Hiroshi; Kitagawa, Noriyuki; Ohkubo, Yohei; Tsukahara, Teruomi; Miyagawa, Shin-ichi;

Surgical Treatment of 144 Cases of Hilar Cholangiocarcinoma Without Liver-Related Mortality
WORLD JOURNAL OF SURGERY,38(5):1164-1176 2014(May)
Author:Furusawa, Norihiko; Kobayashi, Akira; Yokoyama, Takahide; Shimizu, Akira; Motoyama, Hiroaki; Miyagawa, Sin-ichi;

手術,67(13):1819-1824 2013

日本内視鏡外科学会雑誌,18:737-743 2013

Hepatectomy preserving drainage veins of the posterior section for liver malignancy invading the right hepatic vein: an alternative to right hepatectomy
AMERICAN JOURNAL OF SURGERY,204(5):717-723 2012(Nov.)
Author:Shimizu, Akira; Kobayashi, Akira; Yokoyama, Takahide; Nakata, Takenari; Motoyama, Hiroaki; Kubota, Koji; Furusawa, Norihiko; Kitahara, Hiroe; Kitagawa, Noriyuki; Fukushima, Kentaro; Shirota, Tomoki; Miyagawa, Shinichi;

Role of bone marrow cells in the development of pancreatic fibrosis in a rat model of pancreatitis induced by a choline-deficient/ethionine-supplemented diet
Biochem Biophys Res Commun.,420(4):743-9 2012
Author:Akita S, Kubota K, Kobayashi A, Misawa R, Shimizu A, Nakata T, Yokoyama T, Takahashi M, Miyagawa S

Identification of oligopeptide binding to colon cancer cells separated from patients using laser capture microdissection
JOURNAL OF DRUG TARGETING,16(5):396-404 2008
Author:Kubo, Naoki; Akita, Noriyuki; Shimizu, Akira; Kitahara, Hiroe; Parker, Alan L.; Miyagawa, Shinichi;

Identification of an oligopeptide binding to hepatocellular carcinoma
ONCOLOGY,71(1-2):136-145 2006
Author:Shimizu, Akira; Maruta, Fukuto; Akita, Noriyuki; Miwa, Shiro; Seymour, Leonard W.; Kerr, David J.; Parker, Alan L.; Miyagawa, Shinichi;

Hepatic venous reconstruction after concomitant resection for colorectal liver metastases and preoperative evaluation of hepatic venous drainage area
21st World Congress of the IASGO 2011(Nov. 10)
Presenter:Akira Shimizu, Akira Kobayashi, Tomoki Shirota, Kentaro Fukushima, Norihiko Furusawa, Hiroe Kitahara, Koji Kubota, Hiroaki Motoyama, Takenari Nakata, Takahide Yokoyama, Shinichi Miyagawa

第9回日本ヘルニア学会学術集会 2011(Aug. 01)
Presenter:清水 明,横山隆秀,代田智樹,福島健太郎,北原弘恵,古澤徳彦,窪田晃治,本山博章,鈴木史恭,中田岳成,小林 聡,宮川眞一

第66回日本消化器外科学会総会 2011(Jul. 13)
Presenter:清水 明,小林 聡,代田智樹,福島健太郎,北原弘恵,古澤徳彦,窪田晃治,本山博章,鈴木史恭,中田岳成,横山隆秀,宮川眞一

第23回日本肝胆膵外科学会・学術集会 2011(Jun. 08)
Presenter:清水 明,小林 聡,北原弘恵,古澤徳彦,本山博章,窪田晃治,鈴木史恭,中田岳成,横山隆秀,宮川眞一

Research Grants
Grants‐in‐aid for Scientific Research(Research Representative)
2017 - 2019 , ALPPS手術後肝再生促進因子の同定と機能解析 , 基盤研究(C)