博士（医学）

Neuroscience-general, Neurophysiology/General neuroscience

Anatomy, General anatomy (including histology/embryology)

Medical biochemistry, General medical chemistry

Pharmacology, General pharmacology

Pharmacology, Pharmacology

Medical biochemistry, Medical biochemistry

Anatomy, Anatomy

Neuroscience-general, Neuroscience - general

Physiology, Physiology

2014
信州大学学術研究院医学系　分子細胞生理学教室 教授

2012 - 2014
Professor, Shinshu University School of Medicine

2009 - 2012
生理学研究所 准教授

2008 - 2009
Stanford University School of Medicine Life Science Research Associate

2007 - 2008
UT Southwestern Medical Center Instructor

2005 - 2007
UT Southwestern Medical Center Assistant Instructor

2001 - 2005
Postdoctoral fellow UT Southwestern Medical Center

1999 - 2001
Postdoctoral fellow Howard Hughes Medical Institute

1997 - 1999, Osaka University, Graduate School of Medicine, School of Physiology

1989 - 1995, University of Tsukuba, School of Medicine

1989 - 1995, University of Tsukuba, School of Medicine

Analysis of predictors of fever after aortic valve replacement: Diabetic patients are less likely to develop fever after aortic valve replacement, a single-centre retrospective study.
Hiroshi Ishibashi; Yoshiharu Enomoto; Shohei Takaoka; Kazuhiro Aoki; Hiroki Nagai; Kenji Yamagata; Naomi Ishibashi-Kanno; Fumihiko Uchida; Satoshi Fukuzawa; Katsuhiko Tabuchi; Hiroki Bukawa; Yasuyuki Suzuki; Toru Yanagawa
Journal of perioperative practice, 17504589241232503-17504589241232503, Apr. 2024
Lead

Deep-Learning-Based Analysis Reveals a Social Behavior Deficit in Mice Exposed Prenatally to Nicotine
Mengyun Zhou; Wen Qiu; Nobuhiko Ohashi; Lihao Sun; Marie-Louis Wronski; Emi Kouyama-Suzuki; Yoshinori Shirai; Toru Yanagawa; Takuma Mori; Katsuhiko Tabuchi
Cells, 13(3), 275-275, Feb. 2024
Lead

Diverse Clinical Phenotypes of CASK-Related Disorders and Multiple Functional Domains of CASK Protein
Takuma Mori; Mengyun Zhou; Katsuhiko Tabuchi
Genes, Aug. 2023
Lead

Structural Analysis Implicates CASK-Liprin-α2 Interaction in Cerebellar Granular Cell Death in MICPCH Syndrome.
Qi Guo; Emi Kouyama-Suzuki; Yoshinori Shirai; Xueshan Cao; Toru Yanagawa; Takuma Mori; Katsuhiko Tabuchi
Cells, 12(8), Apr. 2023, Refereed
Corresponding

An Epilepsy-Associated Mutation of Salt-Inducible Kinase 1 Increases the Susceptibility to Epileptic Seizures and Interferes with Adrenocorticotropic Hormone Therapy for Infantile Spasms in Mice.
Bo Pang; Takuma Mori; Moataz Badawi; Mengyun Zhou; Qi Guo; Emi Suzuki-Kouyama; Toru Yanagawa; Yoshinori Shirai; Katsuhiko Tabuchi
International journal of molecular sciences, 23(14), Jul. 2022, Refereed
Corresponding

IQSEC3 Deletion Impairs Fear Memory Through Upregulation of Ribosomal S6K1 Signaling in the Hippocampus.
Dongwook Kim; Hyeji Jung; Yoshinori Shirai; Hyeonho Kim; Jinhu Kim; Dongseok Lim; Takuma Mori; Hyojeong Lee; Dongseok Park; Hee Young Kim; Qi Guo; Bo Pang; Wen Qiu; Xueshan Cao; Emi Kouyama-Suzuki; Takeshi Uemura; Enas Kasem; Yu Fu; Seungjoon Kim; Akinori Tokunaga; Takahiro Yoshizawa; Tatsuo Suzuki; Hiroyuki Sakagami; Kea Joo Lee; Jaewon Ko; Katsuhiko Tabuchi*; Ji Won Um* (*Tabuchi and Um are corresponding authors.)
Biological psychiatry, 91(9), 821-831, May 2022, Refereed
Corresponding

Neurexins play a crucial role in cerebellar granule cell survival by organizing autocrine machinery for neurotrophins.
Takeshi Uemura; Emi Suzuki-Kouyama; Shiori Kawase; Taiga Kurihara; Misato Yasumura; Tomoyuki Yoshida; Shuya Fukai; Maya Yamazaki; Peng Fei; Manabu Abe; Masahiko Watanabe; Kenji Sakimura; Masayoshi Mishina; Katsuhiko Tabuchi
Cell reports, 39(1), 110624-110624, Apr. 2022, Refereed
Corresponding

Nasal molding prevents relapse of nasal deformity after primary rhinoplasty in patients with unilateral complete cleft lip: An outcomes-based comparative study of palatal plate alone versus nasoalveolar molding.
Yukiko Aihara; Toru Yanagawa; Masahiro Sasaki; Kaoru Sasaki; Yoichiro Shibuya; Koji Adachi; Shinji Togashi; Shohei Takaoka; Katsuhiko Tabuchi; Hiroki Bukawa; Mitsuru Sekido
Clinical and experimental dental research, 8(1), 197-208, Feb. 2022, Refereed
Lead

IQSEC2 Deficiency Results in Abnormal Social Behaviors Relevant to Autism by Affecting Functions of Neural Circuits in the Medial Prefrontal Cortex.
Anuradha Mehta; Yoshinori Shirai; Emi Kouyama-Suzuki; Mengyun Zhou; Takahiro Yoshizawa; Toru Yanagawa; Takuma Mori; Katsuhiko Tabuchi
Cells, 10(10), Oct. 2021, Refereed
Corresponding

MicroRNA 142-5p promotes tumor growth in oral squamous cell carcinoma via the PI3K/AKT pathway by regulating PTEN.
Seiichiro Iizumi; Fumihiko Uchida; Hiroki Nagai; Shohei Takaoka; Satoshi Fukuzawa; Naomi Ishibashi Kanno; Kenji Yamagata; Katsuhiko Tabuchi; Toru Yanagawa; Hiroki Bukawa
Heliyon, 7(10), e08086-e08086, Oct. 2021, Refereed
Lead

Npas4 regulates IQSEC3 expression in hippocampal somatostatin interneurons to mediate anxiety-like behavior.
Seungjoon Kim; Dongseok Park; Jinhu Kim; Dongwook Kim; Hyeonho Kim; Takuma Mori; Hyeji Jung; Dongsu Lee; Sookyung Hong; Jongcheol Jeon; Katsuhiko Tabuchi; Eunji Cheong; Jaehoon Kim; Ji Won Um; Jaewon Ko
Cell reports, 36(3), 109417-109417, Jul. 2021, Refereed
Lead

Risperidone Mitigates Enhanced Excitatory Neuronal Function and Repetitive Behavior Caused by an ASD-Associated Mutation of SIK1.
Moataz Badawi; Takuma Mori; Taiga Kurihara; Takahiro Yoshizawa; Katsuhiro Nohara; Emi Kouyama-Suzuki; Toru Yanagawa; Yoshinori Shirai; Katsuhiko Tabuchi
Frontiers in molecular neuroscience, 14, 706494-706494, Jul. 2021, Refereed
Corresponding

Non-microtubule tubulin-based backbone and subordinate components of postsynaptic density lattices
Suzuki, Tatsuo; Terada, Nobuo; Higashiyama, Shigeki; Kametani, Kiyokazu; Shirai, Yoshinori; Honda, Mamoru; Kai, Tsutomu; Li, Weidong; Tabuchi, Katsuhiko
LIFE SCIENCE ALLIANCE, 4(7), Jul. 2021, Refereed
Lead

Canonical versus non-canonical transsynaptic signaling of neuroligin 3 tunes development of sociality in mice.
Tomoyuki Yoshida; Atsushi Yamagata; Ayako Imai; Juhyon Kim; Hironori Izumi; Shogo Nakashima; Tomoko Shiroshima; Asami Maeda; Shiho Iwasawa-Okamoto; Kenji Azechi; Fumina Osaka; Takashi Saitoh; Katsumi Maenaka; Takashi Shimada; Yuko Fukata; Masaki Fukata; Jumpei Matsumoto; Hisao Nishijo; Keizo Takao; Shinji Tanaka; Shigeo Okabe; Katsuhiko Tabuchi; Takeshi Uemura; Masayoshi Mishina; Hisashi Mori; Shuya Fukai
Nature communications, 12(1), 1848-1848, Mar. 2021, Refereed
Lead

Inhibition of CASK Expression by Virus-mediated RNA Interference in Medial Prefrontal Cortex Affects Social Behavior in the Adult Mouse
Xueshan, Cao; Wen, Qiu; Bo, Pang; Mengyun, Zhou; Anuradha, Mehta; Qi, Guo; Shirai, Yoshinori; Mori, Takuma; Tabuchi, Katsuhiko
Shinshu Med J, 69(1), 45-52-52, Feb. 2021, Refereed
Corresponding

An Autism-Associated Neuroligin-3 Mutation Affects Developmental Synapse Elimination in the Cerebellum.
Esther Suk King Lai; Hisako Nakayama; Taisuke Miyazaki; Takanobu Nakazawa; Katsuhiko Tabuchi; Kouichi Hashimoto; Masahiko Watanabe; Masanobu Kano
Frontiers in neural circuits, 15, 676891-676891, 2021, Refereed
Lead

Npas4 regulates IQSEC3 expression in hippocampal somatostatin interneurons to mediate anxiety-like behavior
Kim, Seungjoon; Park, Dongseok; Kim, Jinhu; Kim, Dongwook; Kim, Hyeonho; Mori, Takuma; Jung, Hyeji; Lee, Dongsu; Hong, Sookyung; Jeon, Jongcheol; Tabuchi, Katsuhiko; Cheong, Eunji; Kim, Jaehoon; Um, Ji Won; Ko, Jaewon;
CELL REPORTS, 36(3), 109417, 2021

Inhibition of DNA ligase IV enhances the CRISPR/Cas9-mediated knock-in efficiency in mouse brain neurons.
Xueshan Cao; Emi Kouyama-Suzuki; Bo Pang; Taiga Kurihara; Takuma Mori; Toru Yanagawa; Yoshinori Shirai; Katsuhiko Tabuchi
Biochemical and biophysical research communications, 533(3), 449-457, Dec. 2020, Refereed
Corresponding

DNA repair protein RAD51 enhances the CRISPR/Cas9-mediated knock-in efficiency in brain neurons
Kurihara, Taiga; Kouyama-Suzuki, Emi; Satoga, Michiru; Li, Xue; Badawi, Moataz; Thiha; Baig, Deeba Noreen; Yanagawa, Toru; Uemura, Takeshi; Mori, Takuma; Tabuchi, Katsuhiko
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 524(3), 621-628-628, 2020, Refereed
Corresponding

Correction: Deficiency of calcium/calmodulin-dependent serine protein kinase disrupts the excitatory-inhibitory balance of synapses by downregulating GluN2B.
Takuma Mori; Enas A Kasem; Emi Suzuki-Kouyama; Xueshan Cao; Xue Li; Taiga Kurihara; Takeshi Uemura; Toru Yanagawa; Katsuhiko Tabuchi
Molecular psychiatry, 24(7), 1093-1093, Jul. 2019
Corresponding

A small number of residual teeth after the mandibular resection of oral cancer is associated With titanium reconstruction plate exposure
Hiromi, Hirohata; Yanagawa, Toru; Takaoka, Shohei; Yamagata, Kenji; Sasaki, Kaoru; Shibuya, Yoichiro; Uchida, Fumihiko; Fukazawa, Satoshi; Tabuchi, Katsuhiko; Hasegawa, Shogo; Kanno; Naomi Ishibashi; Sekidou, Mitsuru; Bukawa, Hiroki
Clin Exp Dent Res, 5(5), 1-7, May 2019, Refereed, Not invited
Lead

Deficiency of calcium/calmodulin-dependent serine protein kinase disrupts the excitatory-inhibitory balance of synapses by down-regulating GluN2B.
Mori T; Kasem EA; Suzuki-Kouyama E; Cao X; Li X; Kurihara T; Uemura T; Yanagawa T; Tabuchi K
Molecular psychiatry, 24(7), 1079-1092, Jan. 2019, Refereed, Not invited
Corresponding

PTPσ Drives Excitatory Presynaptic Assembly via Various Extracellular and Intracellular Mechanisms.
Han, Kyung Ah; Ko, Ji Seung; Pramanik, Gopal; Kim, Jin Young; Tabuchi, Katsuhiko; Um, Ji Won; Ko, Jaewon
JOURNAL OF NEUROSCIENCE, 38(30), 6700-6721, Jul. 2018, Refereed, Not invited
Lead

Synaptic-Adhesion Molecules Neurexin 1 and Neuroligin 1 as Novel Prognostic Factors in Oral Squamous Cell Carcinoma
Hiromi, Hirohata; Toru, Yanagawa; Shohei, Takaoka; Fumihiko, Uchida; Yoichiro, Shibuya; Satoru, Miyabe; Katsuhiko, Tabuchi; Yuichi, Akagi; Shogo, Hasegawa; Satoshi, Sakai; Yasutoshi, Takeuchi; Naomi, ishibashi-Kanno; Kenji, Yamagata; Hiroki, Bukawa
Journal of Dentistry and Dental Medicine, Mar. 2018, Refereed, Not invited
Lead

Neurexins and neuropsychiatric disorders
Kasem, Enas; Kurihara, Taiga; Tabuchi, Katsuhiko
NEUROSCIENCE RESEARCH, 127, 53-60, Feb. 2018, Refereed, Not invited
Corresponding

Numbers of presynaptic Ca2+ channel clusters match those of functionally defined vesicular docking sites in single central synapses
Takafumi Miki; Walter A. Kaufmann; Gerardo Malagon; Laura Gomez; Katsuhiko Tabuchi; Masahiko Watanabe; Ryuichi Shigemoto; Alain Marty
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 114(26), E5246-E5255, Jun. 2017, Refereed, Not invited
Lead

Corrigendum to “p62 modulates the intrinsic signaling of UVB-induced apoptosis” [Journal of Dermatological Science 83 (2016) 226–233] (S0923181116300755) (10.1016/j.jdermsci.2016.05.005))
Sachiko Ito; Shintaro Kimura; Eiji Warabi; Yasuhiro Kawachi; Masanobu Yamatoji; Fumihiko Uchida; Naomi Ishibashi-Kanno; Kenji Yamagata; Shogo Hasegawa; Junichi Shoda; Katsuhiko Tabuchi; Satoshi Sakai; Hiroki Bukawa; Mitsuru Sekido; Toru Yanagawa
Journal of Dermatological Science, 86(3), 259-260, Jun. 2017, Refereed, Not invited
Lead

Distortion of the normal function of synaptic cell adhesion molecules by genetic variants as a risk for autism spectrum disorders
Baig, Deeba Noreen; Yanagawa, Toru; Tabuchi, Katsuhiko
Brain research bulletin, 129(SI), 82-90, Mar. 2017, Refereed, Not invited
Corresponding

Functions of synapse adhesion molecules neurexin/neuroligins and neurodevelopmental disorders
Xueshan Cao; Katsuhiko Tabuchi
NEUROSCIENCE RESEARCH, 116, 3-9, Mar. 2017, Refereed, Not invited
Corresponding

Central synapse, neural circuit, and brain function
Hideto Takahashi; Keiko Matsuda; Katsuhiko Tabuchi; Jaewon Ko
NEUROSCIENCE RESEARCH, 116, 1-2, Mar. 2017, Refereed, Not invited
Lead

Fluorescent protein tagging of endogenous protein in brain neurons using CRISPR/Cas9-mediated knock-in and in utero electroporation techniques
Takeshi Uemura; Takuma Mori; Taiga Kurihara; Shiori Kawase; Rie Koike; Michiru Satoga; Xueshan Cao; Xue Li; Toru Yanagawa; Takayuki Sakurai; Takayuki Shindo; Katsuhiko Tabuchi
Scientific Reports, 6(1), 35861, Oct. 2016, Refereed, Not invited
Corresponding

p62 modulates the intrinsic signaling of UVB-induced apoptosis
Sachiko, Ito; Shintaro, Kimura; Eiji, Warabi; Yasuhiro, Kawachi; Masanobu, Yamatoji; Fumihiko, Uchida; Naomi, Ishibashi-Kanno; Kenji, Yamagata; Shogo, Hasegawa; Junichi, shoda; Katsuhiko, Tabuchi; Satoshi, Sakai; Hiroki, Bukawa; Mitsuru, Sekido; Toru, Yanagawa
Journal of Dermatological science, May 2016, Not invited
Lead

IQ Motif and SEC7 Domain-containing Protein 3 (IQSEC3) Interacts with Gephyrin to Promote Inhibitory Synapse Formation.
Um JW; Choii G; Park D; Kim D; Jeon S; Kang H; Mori T; Papadopoulos T; Yoo T; Lee Y; Kim E; Tabuchi K; Ko J
The Journal of biological chemistry, 291(19), 10119-10130, Mar. 2016, Refereed, Not invited
Lead

PDZ interaction of Vangl2 links PSD-95 and Prickle2 but plays only a limited role in the synaptic localisation of Vangl2
Tadahiro Nagaoka; Katsuhiko Tabuchi; Masashi Kishi
SCIENTIFIC REPORTS, 5, 12916, Aug. 2015, Refereed, Not invited
Lead

beta-Neurexins Control Neural Circuits by Regulating Synaptic Endocannabinoid Signaling
Garret R. Anderson; Jason Aoto; Katsuhiko Tabuchi; Csaba Foeldy; Jason Covy; Ada Xin Yee; Dick Wu; Sung-Jin Lee; Lu Chen; Robert C. Malenka; Thomas C. Suedhof
CELL, 162(3), 593-606, Jul. 2015, Refereed, Not invited
Lead

Distinct circuit-dependent functions of presynaptic neurexin-3 at GABAergic and glutamatergic synapses
Jason Aoto; Csaba Foeldy; Silviana Maria Ciurea Ilcus; Katsuhiko Tabuchi; Thomas C. Suedhof
NATURE NEUROSCIENCE, 18(7), 997-+, Jul. 2015, Refereed, Not invited
Lead

PTP sigma functions as a presynaptic receptor for the glypican-4/LRRTM4 complex and is essential for excitatory synaptic transmission
Ji Seung Ko; Gopal Pramanik; Ji Won Um; Ji Seon Shim; Dongmin Lee; Kee Hun Kim; Gug-Young Chung; Giuseppe Condomitti; Ho Min Kim; Hyun Kim; Joris de Wit; Kang-Sik Park; Katsuhiko Tabuchi; Jaewon Ko
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 112(6), 1874-1879, Feb. 2015, Refereed, Not invited
Lead

Mandibular reconstruction using plates prebent to fit rapid prototyping 3-dimensional printing models ameliorates contour deformity
Masaki Azuma; Toru Yanagawa; Naomi Ishibashi-Kanno; Fumihiko Uchida; Takaaki Ito; Kenji Yamagata; Shogo Hasegawa; Kaoru Sasaki; Koji Adachi; Katsuhiko Tabuchi; Mitsuru Sekido; Hiroki Bukawa
HEAD & FACE MEDICINE, 10, 45, Oct. 2014, Refereed, Not invited
Lead

Vascular and parenchymal amyloid pathology in an Alzheimer disease knock-in mouse model: interplay with cerebral blood flow
Hongmei Li; Qinxi Guo; Taeko Inoue; Vinicia A. Polito; Katsuhiko Tabuchi; Robert E. Hammer; Robia G. Pautler; George E. Taffet; Hui Zheng
MOLECULAR NEURODEGENERATION, 9, 28, Aug. 2014, Refereed, Not invited
Lead

Enhanced synapse remodelling as a common phenotype in mouse models of autism
Masaaki Isshiki; Shinji Tanaka; Toshihiko Kuriu; Katsuhiko Tabuchi; Toru Takumi; Shigeo Okabe
NATURE COMMUNICATIONS, 5, 4742, Aug. 2014, Refereed, Not invited
Lead

Peroxiredoxin I plays a protective role against UVA irradiation through reduction of oxidative stress
Takaaki Ito; Shintaro Kimura; Kahori Seto; Eiji Warabi; Yasuhiro Kawachi; Junichi Shoda; Katsuhiko Tabuchi; Kenji Yamagata; Shogo Hasegawa; Hiroki Bukawa; Tetsuro Ishii; Toru Yanagawa
JOURNAL OF DERMATOLOGICAL SCIENCE, 74(1), 9-17, Apr. 2014, Refereed, Not invited
Lead

Calsyntenins Function as Synaptogenic Adhesion Molecules in Concert with Neurexins
Ji Won Um; Gopal Pramanik; Ji Seung Ko; Min-Young Song; Dongmin Lee; Hyun Kim; Kang-Sik Park; Thomas C. Suedhof; Katsuhiko Tabuchi; Jaewon Ko
CELL REPORTS, 6(6), 1096-1109, Mar. 2014, Refereed, Not invited
Lead

Synapse maturation and autism: Learning from Neuroligin model mice
Katsuhiko Tabuchi; WenHsin Hang; Nur Farehan Mohamed Asgar; Gopal Pramanik
JAPANESE JOURNAL OF NEUROPSYCHOPHARMACOLOGY, 34(1), 1-4, Feb. 2014, Refereed, Not invited
Lead

Presynaptic Neurexin-3 Alternative Splicing trans-Synaptically Controls Postsynaptic AMPA Receptor Trafficking
Jason Aoto; David C. Martinelli; Robert C. Malenka; Katsuhiko Tabuchi; Thomas C. Suedhof
CELL, 154(1), 75-88, Jul. 2013, Refereed, Not invited
Lead

Neuroligin-1 controls synaptic abundance of NMDA-type glutamate receptors through extracellular coupling
Elaine C. Budreck; Oh-Bin Kwon; Jung Hoon Jung; Stephane Baudouin; Albert Thommen; Hye-Sun Kim; Yugo Fukazawa; Harumi Harada; Katsuhiko Tabuchi; Ryuichi Shigemoto; Peter Scheiffele; Joung-Hun Kim
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 110(2), 725-730, Jan. 2013, Not invited
Lead

Soluble amyloid precursor protein (APP) regulates transthyretin and Klotho gene expression without rescuing the essential function of APP (vol 107, pg 17362, 2010)
Li, Hongmei; Wang, Baiping; Wang, Zilai; Guo, Qinxi; Tabuchi, Katsuhiko; Hammer, Robert E; Suedhof, Thomas C; Zheng, Hui
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 110(32), 13228-13228, 2013, Not invited
Lead

A novel method for evaluating postsurgical results of unilateral cleft lip and palate with the use of Hausdorff distance: presurgical orthopedic treatment improves nasal symmetry after primary cheiloplasty
Rei Karube; Hiroyoshi Sasaki; Shinji Togashi; Toru Yanagawa; Shizuo Nakane; Naomi Ishibashi; Kenji Yamagata; Kojiro Onizawa; Koji Adachi; Katsuhiko Tabuchi; Mitsuru Sekido; Hiroki Bukawa
ORAL SURGERY ORAL MEDICINE ORAL PATHOLOGY ORAL RADIOLOGY, 114(6), 704-711, Dec. 2012, Refereed, Not invited
Lead

Presurgical Nasoalveolar Molding Orthopedic Treatment Improves the Outcome of Primary Cheiloplasty of Unilateral Complete Cleft Lip and Palate, as Assessed by Naris Morphology and Cleft Gap
Hiroyoshi Sasaki; Shinji Togashi; Rei Karube; Toru Yanagawa; Shizuo Nakane; Katsuhiko Tabuchi; Naomi Ishibashi; Yoshiko Shinya; Hiroyuki Ito; Kenji Yamagata; Kojiro Onizawa; Koji Adachi; Mitsuru Sekido; Hiroki Bukawa
JOURNAL OF CRANIOFACIAL SURGERY, 23(6), 1596-1601, Nov. 2012, Refereed, Not invited
Lead

Analysis of Neuroligin-3 R451C knock-in mice as models for autistic savant
Baig Deeba Noreen; Yanagawa Toru; Tabuchi Katsuhiko
Japanese Journal of Biological Psychiatry, 23(4), 281-286, 2012
Lead

Autism-linked neuroligin-3 R451C mutation differentially alters hippocampal and cortical synaptic function
Mark Etherton; Csaba Foeldy; Manu Sharma; Katsuhiko Tabuchi; Xinran Liu; Mehrdad Shamloo; Robert C. Malenka; Thomas C. Suedhof
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 108(33), 13764-13769, Aug. 2011, Refereed, Not invited
Lead

An autism-associated point mutation in the neuroligin cytoplasmic tail selectively impairs AMPA receptor-mediated synaptic transmission in hippocampus
Mark R. Etherton; Katsuhiko Tabuchi; Manu Sharma; Jaewon Ko; Thomas C. Suedhof
EMBO JOURNAL, 30(14), 2908-2919, Jul. 2011, Refereed, Not invited
Lead

Genetic Dissection of the Amyloid Precursor Protein in Developmental Function and Amyloid Pathogenesis
Hongmei Li; Zilai Wang; Baiping Wang; Qinxi Guo; Georgia Dolios; Katsuhiko Tabuchi; Robert E. Hammer; Thomas C. Suedhof; Rong Wang; Hui Zheng
JOURNAL OF BIOLOGICAL CHEMISTRY, 285(40), 30598-30605, Oct. 2010, Refereed, Not invited
Lead

Soluble amyloid precursor protein (APP) regulates transthyretin and Klotho gene expression without rescuing the essential function of APP
Hongmei Li; Baiping Wang; Zilai Wang; Qinxi Guo; Katsuhiko Tabuchi; Robert E. Hammer; Thomas C. Suedhof; Hui Zheng
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 107(40), 17362-17367, Oct. 2010, Refereed, Not invited
Lead

COCHLEAR PROTECTION FROM ACOUSTIC INJURY BY INHIBITORS OF p38 MITOGEN-ACTIVATED PROTEIN KINASE AND SEQUESTOSOME 1 STRESS PROTEIN
K. Tabuchi; K. Oikawa; T. Hoshino; B. Nishimura; K. Hayashi; T. Yanagawa; E. Warabi; T. Ishii; S. Tanaka; A. Hara
NEUROSCIENCE, 166(2), 665-670, Mar. 2010, Refereed, Not invited
Lead

Neuroligin-1 Deletion Results in Impaired Spatial Memory and Increased Repetitive Behavior
Jacqueline Blundell; Cory A. Blaiss; Mark R. Etherton; Felipe Espinosa; Katsuhiko Tabuchi; Christopher Walz; Marc F. Bolliger; Thomas C. Suedhof; Craig M. Powell
JOURNAL OF NEUROSCIENCE, 30(6), 2115-2129, Feb. 2010, Refereed, Not invited
Lead

Disruption of LGI1-linked synaptic complex causes abnormal synaptic transmission and epilepsy
Yuko Fukata; Kathryn L. Lovero; Tsuyoshi Iwanaga; Atsushi Watanabe; Norihiko Yokoi; Katsuhiko Tabuchi; Ryuichi Shigemoto; Roger A. Nicoll; Masaki Fukata
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 107(8), 3799-3804, Feb. 2010, Refereed, Not invited
Lead

Conditional Forebrain Inactivation of Nicastrin Causes Progressive Memory Impairment and Age-Related Neurodegeneration
Katsuhiko Tabuchi; Guiquan Chen; Thomas C. Suedhof; Jie Shen
JOURNAL OF NEUROSCIENCE, 29(22), 7290-7301, Jun. 2009, Refereed, Not invited
Lead

Increased anxiety-like behavior in mice lacking the inhibitory synapse cell adhesion molecule neuroligin 2
J. Blundell; K. Tabuchi; M. F. Bolliger; C. A. Blaiss; N. Brose; X. Liu; T. C. Sudhof; C. M. Powell
GENES BRAIN AND BEHAVIOR, 8(1), 114-126, Feb. 2009, Refereed, Not invited
Lead

シナプス, Neuroliginと自閉症
田渕克彦
Cognition and Dementia, 8(3), 203-208, 2009, Not invited
Lead

自閉症とニューロリギン
田渕克彦
Clinical Neuroscience, 27(10), 1092-1093, 2009, Not invited
Lead

素顔のニューロサイエンティスト Thomas C Sudhof
田渕克彦
Clinical Neuroscience, 27(8), 944, 2009, Not invited
Lead

シナプス機能と自閉症：ニューロリギン遺伝子改変マウスを用いた自閉症病理の探求
田渕克彦
実験医学, 26(4), 545-546, 2008, Not invited
Lead

Neuroligin-3 mutation implicated in autism increases inhibitory synaptic transmission in mice
Katsuhiko Tabuchi; Jacqueline Blundell; Mark R. Etherton; Robert E. Hammer; Xinran Liu; Craig M. Powell; Thomas C. Suedhof
SCIENCE, 318(5847), 71-76, Oct. 2007, Refereed, Not invited
Lead

Loss of cytokeratin 13 expression in squamous cell carcinoma of the tongue is a possible sign for local recurrence
T. Yanagawa; H. Yoshida; K. Yamagata; K. Onizawa; K. Tabuchi; Y. Koyama; S. Iwasa; H. Shimoyamada; H. Harada; K. Omura
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH, 26(2), 215-220, Jun. 2007, Refereed, Not invited
Lead

Deletion of alpha-neurexins does not cause a major impairment of axonal pathfinding or synapse formation
Irina Dudanova; Katsuhiko Tabuchi; Astrid Rohlmann; Thomas C. Suedhof; Markus Missler
JOURNAL OF COMPARATIVE NEUROLOGY, 502(2), 261-274, May 2007, Refereed, Not invited
Lead

Genetic analysis of Mint/X11 proteins: Essential presynaptic functions of a neuronal adaptor protein family
Angela Ho; Wade Morishita; Deniz Atasoy; Xinran Liu; Katsuhiko Tabuchi; Robert E. Hammer; Robert C. Malenka; Thomas C. Sudhof
JOURNAL OF NEUROSCIENCE, 26(50), 13089-13101, Dec. 2006, Refereed, Not invited
Lead

Nicastrin functions as a gamma-secretase-substrate receptor
S Shah; SF Lee; K Tabuchi; YH Hao; C Yu; Q LaPlant; H Ball; CE Dann; T Sudhof; G Yu
CELL, 122(3), 435-447, Aug. 2005, Refereed, Not invited
Lead

Differences in care-seeking behavior for acute chest pain in the United States and Japan
L Liao; DJ Whellan; K Tabuchi; KA Schulman
AMERICAN HEART JOURNAL, 147(4), 630-635, Apr. 2004, Refereed, Not invited
Lead

Drosophila homeodomain protein REPO controls glial differentiation by cooperating with ETS and BTB transcription factors
Y Yuasa; M Okabe; S Yoshikawa; K Tabuchi; WC Xiong; Y Hiromi; H Okano
DEVELOPMENT, 130(11), 2419-2428, Jun. 2003, Refereed, Not invited
Lead

CASK participates in alternative tripartite complexes in which Mint 1 competes for binding with Caskin 1, a novel CASK-binding protein
K Tabuchi; T Biederer; S Butz; TC Sudhof
JOURNAL OF NEUROSCIENCE, 22(11), 4264-4273, Jun. 2002, Refereed, Not invited
Lead

Structure and evolution of neurexin genes: Insight into the mechanism of alternative splicing
K Tabuchi; TC Sudhof
GENOMICS, 79(6), 849-859, Jun. 2002, Refereed, Not invited
Lead

Embryonic neuronal death due to neurotrophin and neurotransmitter deprivation occurs independent of APAF-1
N Honarpour; K Tabuchi; JM Stark; RE Hammer; TC Sudhof; LF Parada; Wang, X; JA Richardson; J Herz
NEUROSCIENCE, 106(2), 263-274, 2001, Refereed, Not invited
Lead

Peroxiredoxin I expression in oral cancer: a potential new tumor marker
T Yanagawa; S Iwasa; T Ishii; K Tabuchi; H Yusa; K Onizawa; K Omura; H Harada; H Suzuki; H Yoshida
CANCER LETTERS, 156(1), 27-35, Aug. 2000, Refereed, Not invited
Lead

c-Abl expression in oral squamous cell carcinomas
T Yanagawa; H Harada; S Iwasa; K Tabuchi; K Omura; H Suzuki; H Yusa; K Yamagata; K Onizawa; T Ishii; H Yoshida
ORAL ONCOLOGY, 36(1), 89-94, Jan. 2000, Refereed, Not invited
Lead

GAL4/UAS-WGA system as a powerful tool for tracing Drosophila transsynaptic neural pathways
K Tabuchi; K Sawamoto; E Suzuki; K Ozaki; M Sone; C Hama; T Tanifuji-Morimoto; Y Yuasa; Y Yoshihara; A Nose; H Okano
JOURNAL OF NEUROSCIENCE RESEARCH, 59(1), 94-99, Jan. 2000, Refereed, Not invited
Lead

Peroxiredoxin I expression in human thyroid tumors
T Yanagawa; T Ishikawa; T Ishii; K Tabuchi; S Iwasa; S Bannai; K Omura; H Suzuki; H Yoshida
CANCER LETTERS, 145(1-2), 127-132, Oct. 1999, Refereed, Not invited
Lead

Heme oxygenase-1 expression in oral squamous cell carcinoma as involved in lymph node metastasis
MH Tsuji; T Yanagawa; S Iwasa; K Tabuchi; K Onizawa; S Bannai; H Toyooka; H Yoshida
CANCER LETTERS, 138(1-2), 53-59, Apr. 1999, Refereed, Not invited
Lead

A genetic approach to visualization of multisynaptic neural pathways using plant lectin transgene
Y Yoshihara; T Mizuno; M Nakahira; M Kawasaki; Y Watanabe; H Kagamiyama; K Jishage; O Ueda; H Suzuki; K Tabuchi; K Sawamoto; H Okano; T Noda; K Mori
NEURON, 22(1), 33-41, Jan. 1999, Refereed, Not invited
Lead

The regulatory mechanisms of neural development: Roles of cell-autonomous and non-cell-autonomous cues in cell-fate decisions
H Okano; Y Kaneko; Y Nakamura; W Akamatsu; Y Yuasa; T Imai; Y Hirota; MH Jin; K Tabuchi; A Taguchi; M Okabe; S Sakakibara; T Goto; Y Uchiyama; K Sawamoto
NEURAL DEVELOPMENT-BOOK, 2, 9-23, 1999, Refereed, Not invited
Lead

A novel Drosophila paired-like homeobox gene related to Caenorhabditis elegans unc-4 is expressed in subsets of postmitotic neurons and epidermal cells
K Tabuchi; S Yoshikawa; Y Yuasa; K Sawamoto; H Okano
NEUROSCIENCE LETTERS, 257(1), 49-52, Nov. 1998, Refereed, Not invited
Lead

Localization of 5-HT2A receptor in rat cerebral cortex and olfactory system revealed by immunohistochemistry using two antibodies raised in rabbit and chicken
S Hamada; K Senzaki; K Hamaguchi-Hamada; K Tabuchi; H Yamamoto; T Yamamoto; S Yoshikawa; H Okano; N Okado
MOLECULAR BRAIN RESEARCH, 54(2), 199-211, Mar. 1998, Refereed, Not invited
Lead

A novel method for evaluating postsurgical results of unilateral cleft lip and palate with the use of Hausdorff distance: presurgical orthopedic treatment improves nasal symmetry after primary cheiloplasty
Rei Karube; Hiroyoshi Sasaki; Shinji Togashi; Toru Yanagawa; Shizuo Nakane; Naomi Ishibashi; Kenji Yamagata; Kojiro Onizawa; Koji Adachi; Katsuhiko Tabuchi; Mitsuru Sekido; Hiroki Bukawa

Corrigendum to “p62 modulates the intrinsic signaling of UVB-induced apoptosis” [Journal of Dermatological Science 83 (2016) 226–233] (S0923181116300755) (10.1016/j.jdermsci.2016.05.005))
Sachiko Ito; Shintaro Kimura; Eiji Warabi; Yasuhiro Kawachi; Masanobu Yamatoji; Fumihiko Uchida; Naomi Ishibashi-Kanno; Kenji Yamagata; Shogo Hasegawa; Junichi Shoda; Katsuhiko Tabuchi; Satoshi Sakai; Hiroki Bukawa; Mitsuru Sekido; Toru Yanagawa

Differences in care-seeking behavior for acute chest pain in the United States and Japan
L Liao; DJ Whellan; K Tabuchi; KA Schulman

Embryonic neuronal death due to neurotrophin and neurotransmitter deprivation occurs independent of APAF-1
N Honarpour; K Tabuchi; JM Stark; RE Hammer; TC Sudhof; LF Parada; Wang, X; JA Richardson; J Herz

Mandibular reconstruction using plates prebent to fit rapid prototyping 3-dimensional printing models ameliorates contour deformity
Masaki Azuma; Toru Yanagawa; Naomi Ishibashi-Kanno; Fumihiko Uchida; Takaaki Ito; Kenji Yamagata; Shogo Hasegawa; Kaoru Sasaki; Koji Adachi; Katsuhiko Tabuchi; Mitsuru Sekido; Hiroki Bukawa

Peroxiredoxin I plays a protective role against UVA irradiation through reduction of oxidative stress
Takaaki Ito; Shintaro Kimura; Kahori Seto; Eiji Warabi; Yasuhiro Kawachi; Junichi Shoda; Katsuhiko Tabuchi; Kenji Yamagata; Shogo Hasegawa; Hiroki Bukawa; Tetsuro Ishii; Toru Yanagawa

Vascular and parenchymal amyloid pathology in an Alzheimer disease knock-in mouse model: interplay with cerebral blood flow
Hongmei Li; Qinxi Guo; Taeko Inoue; Vinicia A. Polito; Katsuhiko Tabuchi; Robert E. Hammer; Robia G. Pautler; George E. Taffet; Hui Zheng

日本生物学的精神医学会誌 23 4
Single work, Analysis of Neuroligin-3 R451C knock-in mice as models for autistic savant
281-286 2012

Synapse maturation and autism : The role of synapse adhesion molecules
Tabuchi, Katsuhiko; Chang Wen Hsin; Nur Farehan; Asgar Mohamed; Thomas, Sudhof C; Shigemoto, Ryuichi
JOURNAL OF PHYSIOLOGICAL SCIENCES, 2013, Not invited

Genetic Animal Models of Autism
Blundell, Jacqueline; Blaiss, Cory A; Etherton, Mark R; Zhou, Jing; Kwon, Chang-Hyuk; Espinosa, Felipe; Tabuchi, Katsuhiko; Bolliger, Marc E; Parada, Luis F; Sudhof, Thomas C; Powell; Craig M
ANNALS OF NEUROLOGY, 2010, Not invited

Novel Genetic Animal Models of Autism: Molecular Mechanisms to Therapeutic Targets
Powell; Craig M; Blundell, Jacqueline; Tabuchi, Katsuhiko; Zhou, Jing; Kwon, Chang; Etherton, Mark; Hammer, Robert; Liu, Xinran; Parada, Luis; Sudhof, Thomas C
NEUROLOGY, 2009, Not invited

Analysis of neuroligin-3 knock-in mice relevant to autism spectrum disorders
Tabuchi, Katsuhiko; Etherton, Mark; Shigemoto, Ryuichi; Sudhof, Thomas
NEUROSCIENCE RESEARCH, 2009, Not invited

Genetic Animal Models of Autism: Molecular Mechanisms and Potential Therapeutics
Blundell, Jacqueline; Blaiss, Cory; Tabuchi, Katsuhiko; Zhou, Jing; Kwon, Chang; Bolliger, Marc; Parada, Luis; Sudhof, Thomas C; Powell; Craig M
ANNALS OF NEUROLOGY, 2009, Not invited

Autism as synapsopathy: Animal models based on genetic mutations in trans-synaptic cell adhesion molecules
Blundell, Jacqueline; Tabuchi, Katsuhiko; Bolliger, Marc; Brose, Nils; Sudhof, Thomas C; Powell; Craig M
ANNALS OF NEUROLOGY, 2008, Not invited

Neuroligin deletion results in autism & mental retardation-related behavioral abnormalities
Blundell, Jacqueline; Tabuchi, Katsuhiko; Bolliger, Marc; Brose, Nils; Sudhof, Thomas C; Powell; Craig M
ANNALS OF NEUROLOGY, 2007, Not invited

生化学II
Shinshu University

neurophysiology
Shinshu University

北米神経科学会

日本生化学会

日本解剖学会

日本生理学会

日本神経科学会

X染色体不活性化がMICPCH症候群の脳機能障害を起こす神経回路メカニズムの解明
科学研究費補助金, 基盤研究（B)
01 Apr. 2019 - 31 Mar. 2022

Neurexinの結合特異性を操作したマウスを用いた自閉症の分子経路の解明
科学研究費補助金, 基盤研究(B)
01 Apr. 2013 - 31 Mar. 2017

口腔癌におけるシナプス接着因子を標的とした新規抗血管新生療法の探索
科学研究費補助金, 挑戦的萌芽研究
01 Apr. 2013 - 31 Mar. 2015

ＤＲＥＡＤＤシステムを用いたシナプス成熟技術の開発
科学研究費補助金, 挑戦的萌芽研究
01 Apr. 2012 - 31 Mar. 2015

神経伝達物質受容体のシナプス膜面での動態を規定する分子のスクリーニング技術の開発
科学研究費補助金, 挑戦的萌芽研究
2011 - 2012

CASKノックアウトマウスを用いた口蓋裂形成シグナルの解明
科学研究費補助金, 挑戦的萌芽研究
2011 - 2012

精神発達障害原因解明のためのNeuroligin/Neurexinモデルの確立
科学技術振興機構: さきがけ
2009 - 2015

Neuroligin遺伝子改変自閉症モデルマウスのシナプス機能の解析
科学研究費補助金, 研究活動スタート支援
2009 - 2010