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Takeno Seiki|Shinshu University Researcher List

Takeno Seiki

Academic Assembly School of Science and Technology Institute of Agriculture

Faculty of Agriculture Department of Agricultural and Life Sciences Division of Bioscience and Biotechnology 

Associate Professor 

Degree

  • Ph. D., 京都大学(日本)

Field Of Study

  • Applied microbiology

Career

  • 2015
    信州大学学術研究院農学系 准教授
  • 2014 - 2015
    信州大学学術研究院農学系 助教
  • 2007 - 2014
    Assistant Professor, Shinshu University
  • 2005 - 2007
    AssistantProfessor, Shinshu University
  • 2005 - 2005
    京都大学 産学官連携研究員
  • 2004 - 2005
    京都大学 産学連携研究員
  • 2004 - 2004
    京都大学 教務補佐員

Educational Background

  • 2001, Yamaguchi University, Graduate School of Agriculture, 生物資源科学専攻
  • 1999, Yamaguchi University, Faculty of Agriculture, 生物資源科学科
  • 2004, Kyoto University, Graduate School of Agriculture, Division of Applied Life Sciences

Award

  • 2021
    Spotlight article【米国微生物学会誌(Appl Environ Microbiol)】
  • 2020
    日本農芸化学会2020年度大会トピックス演題選出(1598演題中の31演題)

Paper

  • Metabolic engineering to produce palmitic acid or palmitoleic acid in an oleic acid-producing Corynebacterium glutamicum strain
    Takeno S, Hirata Y, Kitamura K, Ohtake T, Aoki K, Murata N, Hayashi M, Ikeda M.
    Metab. Eng., 78, 148-158, Jul. 2023, Refereed
    Lead電子ジャーナル
  • A Futile Metabolic Cycle of Fatty Acyl Coenzyme A (Acyl-CoA) Hydrolysis and Resynthesis in Corynebacterium glutamicum and Its Disruption Leading to Fatty Acid Production
    Ikeda M, Takahashi K, Ohtake T, Imoto R, Kawakami H, Hayashi M, Takeno S.
    Appl. Environ. Microbiol., 87(4), e02469-20, Feb. 2021, RefereedWebofScienceリポジトリ電子ジャーナル
  • The accD3 gene for mycolic acid biosynthesis as a target for improving fatty acid production by fatty acid-producing Corynebacterium glutamicum strains
    Takeno S, Murata N, Kura M, Takasaki M, Hayashi M, Ikeda M.
    Appl. Microbiol. Biotechnol., 102(24), 10603-10612, Dec. 2018, RefereedWebofScienceリポジトリ電子ジャーナル
  • In vivo roles of fatty acid biosynthesis enzymes in biosynthesis of biotin and α-lipoic acid in Corynebacterium glutamicum
    Ikeda M, Nagashima T, Nakamura E, Kato R, Ohshita M, Hayashi M, Takeno S.
    Appl. Environ. Microbiol., 83(19), e01322-17, Oct. 2017, Refereed電子ジャーナル
  • L-Lysine production independent of the oxidative pentose phosphate pathway by Corynebacterium glutamicum with the Streptococcus mutans gapN gene
    Takeno S, Hori K, Ohtani S, Mimura A, Mitsuhashi S, Ikeda M.
    Metab. Eng., 37, 1-10, 2016, RefereedWebofScienceリポジトリ電子ジャーナル
  • A third glucose uptake bypass in Corynebacterium glutamicum ATCC 31833
    Ikeda M, Noguchi N, Ohshita M, Senoo A, Mitsuhashi S, Takeno S.
    Appl. Microbiol. Biotechnol., 99, 2741-2750, 2015WebofScienceリポジトリ電子ジャーナル
  • Significance of the Cgl1427 gene encoding cytidylate kinase in microaerobic growth of Corynebacterium glutamicum
    Takeno S, Shirakura D, Tsukamoto N, Mitsuhashi S, Ikeda M.
    Appl. Microbiol. Biotechnol., 97, 1259-1267, 2013WebofScienceリポジトリ電子ジャーナル
  • Development of Biotin-Prototrophic and -Hyperauxotrophic Corynebacterium glutamicum Strains
    Ikeda M, Miyamoto A, Mutoh S, Kitano Y, Tajima M, Shirakura D, Takasaki M, Mitsuhashi S, Takeno S.
    Appl. Environ. Microbiol., 79, 4586-4594, 2013WebofScienceリポジトリ電子ジャーナル
  • Development of Fatty Acid-Producing Corynebacterium glutamicum Strains
    Takeno S, Takasaki M, Urabayashi A, Mimura A, Muramatsu T, Mitsuhashi S, Ikeda M.
    Appl. Environ. Microbiol., 79, 6776-6783, 2013WebofScienceリポジトリ電子ジャーナル
  • Identification and application of a different glucose uptake system that functions as an alternative to the phosphotransferase system in Corynebacterium glutamicum
    Ikeda M, Mizuno Y, Awane S, Hayashi M, Mitsuhashi S, Takeno S.
    Appl. Microbiol. Biotechnol., 90, 1443-1451, 2011WebofScienceリポジトリ電子ジャーナル
  • Engineering of Corynebacterium glutamicum with an NADPH-generating glycolytic pathway for L-lysine production
    Takeno S, Murata R, Kobayashi R, Mitsuhashi S, Ikeda M.
    Appl. Environ. Microbiol., 76, 7154-7160, 2010WebofScienceリポジトリ電子ジャーナル
  • Elucidation of Genes Relevant to the Microaerobic Growth of Corynebacterium glutamicum
    Ikeda M, Baba M, Tsukamoto N, Komatsu T, Mitsuhashi S, Takeno S.
    Biosci. Biotechnol. Biochem., 73, 2806-2808, 2009
  • Characterization of mutations induced by N-methyl-N'-nitro-N-nitrosoguanidine in an industrial Corynebacterium glutamicum strain
    Ohnishi J, Mizoguchi H, Takeno S, Ikeda M.
    Mutat. Res., 649, 239-244, 2008
  • The Cgl1281-encoding putative transporter of the cation diffusion facilitator family is responsible foralkali-tolerance in Corynebacterium glutamicum
    Takeno S, Nakamura M, Fukai R, Ohnishi J, Ikeda M.
    Arch. Microbiol., 190, 531-538, 2008
  • Anaerobic growth and potential for amino acid production by nitrate respiration in Corynebacterium glutamicum
    Takeno S, Ohnishi J, Komatsu T, Masaki T, Sen K, Ikeda M.
    Appl. Microbiol. Biotechnol., 75, 1173-1182, 2007
  • Molecular Evidence That the Rate-Limiting Step for the Biosynthesis of Arachidonic Acid in Mortierella alpina Is at the Level of an Elongase
    Takeno S, Sakuradani E, Murata S, Inohara-Ochiai M, Kawashima H, Ashikari T, Shimizu S.
    Lipids, 40, 25-30, 2005
  • Improvement of the Fatty Acid Composition of an Oil-Producing Filamentous Fungus, Mortierella alpina 1S-4, through RNA Interference with delta12-Desaturase Gene Expression
    Takeno S, Sakuradani E, Tomi A, Inohara-Ochiai M, Kawashima H, Ashikari T, Shimizu S.
    Appl. Environ. Microbiol., 71, 5124-5128, 2005
  • Transformation of Oil-Producing Fungus, Mortierella alpina 1S-4, Using Zeocin, and Application to Arachidonic Acid Production
    Takeno S, Sakuradani E, Tomi A, Inohara-Ochiai M, Kawashima H, Shimizu S.
    J. Biosci. Bioeng., 100, 617-622, 2005
  • Cloning and Sequencing of the ura3 and ura5 Genes, and Isolation and Characterization of Uracil Auxotrophs of the Fungus Mortierella alpina 1S-4
    Takeno S, Sakuradani E, Murata S, Inohara-Ochiai M, Kawashima H, Ashikari T, Shimizu S.
    Biosci. Biotechnol. Biochem., 68, 277-285, 2004
  • Establishment of an Overall TransformationSystem for an Oil-Producing Filamentous Fungus, Mortierella alpina 1S-4
    Takeno S, Sakuradani E, Murata S, Inohara-Ochiai M, Kawashima H, Ashikari T, Shimizu S.
    Appl. Microbiol. Biotechnol., 65, 419-425, 2004
  • Enzymes Responsible for Acetate Oxidation by Acetic Acid Bacteria
    Saeki A, Matsushita K, Takeno S, Taniguchi M, Toyama H, Theeragool G, Lotong N, Adachi O.
    Biosci. Biotechnol. Biochem., 63, 2102-2109, 1999

MISC

  • ミュータンス菌型糖代謝による新規発酵技術
    竹野誠記,池田正人
    ケミカルエンジニヤリング, 62(9), 625-633, 01 Sep. 2017
  • シクロプロパン脂肪酸の役割
     竹野誠記
    生物工学会誌, 85, 83, 2007
  • 油脂をつくる微生物の探索と育種 -最近の進歩-
     竹野誠記,櫻谷英治、清水昌
    学術月報, 58, 757-761, 2005
  • 油糧微生物Mortierella aplina1S-4における宿主-ベクター系の開発とその応用
     竹野誠記,櫻谷英治、清水昌
    応用微生物学研究, 2, 82-87, 2004

Books and other publications

  • Corynebacterium glutamicum -Biology and Biotechnology-, 2nd Edition, Microbiology Monographs 23
    Ikeda M, Takeno S, Recent Advances in Amino Acid Production
    Springer, 175-226 Apr. 2020
  • Genetic Transformation Systems in Fungi, Volume 1
    Sakuradani E, Kikukawa H, Takeno S, Ando A, Shimizu S, Ogawa J., Joint work, Transformation of Zygomycete Mortierella alpina Using Biolistic Particle Bombardment
    Springer, 135-140 2014
  • Corynebacterium glutamicum -Biology and Biotechnology-, Microbiology Monographs 23
    Ikeda M, Takeno S., Amino Acid Production by Corynebacterium glutamicum
    Springer, 107-147 2013
  • Manual of Industrial Microbiology and Biotechnology, 3rd Edition
    Ikeda M, Takeno S., Genetic Engineering of Corynebacteria
    225-237 2010
  • Biocatalysis and Biotechnology for Functional Foods and Industrial Products
    Sakuradani E, Takeno S, Abe T, Ogawa J, Shimizu S., Arachidonic Acid-Producing Mortierella alpina: Molecular Breeding of Mutants and Creation and Application of a Host-Vector System
    267-282 2006
  • Single Cell Oils
    Sakuradani E, Takeno S, Abe T, Shimizu S., Arachidonic Acid-Producing Mortierella alpina: Creation of Mutants and Molecular Breeding.
    21-35 2005

Lectures, oral presentations, etc.

  • コリネ型アミノ酸生産菌における還元力(NADPH)産生の代謝工学
    竹野誠記,村田了祐,妹尾彰宏,三橋 敏,池田正人
    日本農芸化学会2011年度大会 シンポジウム(講演番号 4SY22-2), 28 Mar. 2011
  • アミノ酸生産菌を用いた脂質発酵へのアプローチ
    竹野誠記
    日本農芸化学会中部支部 第157回例会 若手シンポジウム, 14 Nov. 2009, 日本農芸化学会中部支部, Invited

Affiliated academic society

  • Japan Society for Bioscience, Biotechnology, and Agrochemistry
  • The Society for Biotechnology, Japan

Research Themes

  • 鉄の獲得に着目したパルミトレイン酸生産菌の改良
    科学研究費補助金, 基盤研究(C)
    2022 - 2024
  • パルミトレイン酸生産菌の開発
    科学研究費補助金, 基盤研究(C)
    2019 - 2021
  • コリネ型細菌における長鎖脂肪酸排出輸送体の同定
    科学研究費補助金, 若手研究(B)
    2014 - 2016
  • Metabolic engineering and molecular breeding of amino acid-producing bacteria

Industrial Property Rights

  • 有用物質の製造法,特許5897197(2016.3.11登録), Patent right
  • 有用物質の製造法,特許5833311(2015.11.6登録), Patent right
  • 有用物質の製造方法,特許5537818 (2014.5.9登録), Patent right
  • Process for producing useful substance,US8530203 (2013.9.10登録), Patent right