
KATAYAMA Shigeru
Academic Assembly School of Science and Technology Institute of Agriculture
Institute for Biomedical Sciences
Professor
Researcher Information
Web site
Research activity information
Paper
- Effects of natto-derived fractions on liver metabolic markers and cognitive function in high-fat diet-fed mice
Zheng, Y.; Gokan, T.; Nishikawa, T.; Katayama, S.
Jpn J Food Chem Safety, 2025, Refereed
Lead - Characterization and anti-tumor activities of polysaccharide isolated from Brassica rapa L. via activation of macrophages through TLR2-and TLR4-Dependent pathways
Rina Matsui, Katsunori Endo, Takeru Saiki, Hazuki Haga, Weidong Shen, Xiangdong Wang, Shinya Yamazaki, Shigeru Katayama, Kenji Nagata, Hidemitsu Kitamura Sachi Tanaka
Archives of Biochemistry and Biophysics, 752, 109879, 2024 - Genistein enhances NADC biosynthesis by upregulating nicotinamide phosphoribosyltransferase in adipocytes
Shun Watanabe , Riki Haruyama , Koji Umezawa , Ikuo Tomioka , Soichiro Nakamura , Shigeru Katayama , Takakazu Mitani
The Journal of Nutritional Biochemistry, 121, 109433, Nov. 2023, Refereed - Fermented soybean foods (natto) ameliorate age-related cognitive decline by hippocampal TAAR1-mediated activation of CaMKII/CREB/BDNF signaling pathway in senescence-accelerated mouse prone 8 (SAMP8)
Yifeng Zheng, Mayu Yasuda, Mizuki Yamao, Toshiya Gokan, Yudai Sejima, Takanobu Nishikawa, and Shigeru Katayama*
Food & Function, (14), 10097, Oct. 2023, Refereed
Corresponding - Lacticaseibacillus paracasei K71 alleviates UVB-induced skin barrier dysfunction by attenuating inflammation via IL-10 production in mice
Shigeru Katayama, Rio Yamazaki, Hikaru Umise, Hsu Pei Han,Toshihiro Mihara, Kimiko Uchiyama, Hajime Takahashi, Soichiro Nakamura
Molecular Nutrition and Food Research, 67(16), e2200212, Aug. 2023 - Antioxidant and Antimicrobial Activities of Thai Edible Plant Extracts Prepared Using Different Extraction Techniques
Pimmada Junsathian, Soichiro Nakamura, Shigeru Katayama*, Saroat Rawdkuen
MOLECULES, Sep. 2022, Refereed
Corresponding - Intestinal permeability of agaro-oligosaccharides: Transport across Caco-2 cell monolayers and pharmacokinetics in rats
Ikuya Shirai, Koji Karasawa, Yusuke Kodaira, Yu Iwasaki, Yasutaka Shigemura, Hidefumi Makabe, Shigeru Katayama*
Frontiers in Nutrition, Aug. 2022, Refereed
Corresponding - Buckwheat flour and its starch prevent age-related cognitive decline by increasing hippocampal BDNF production in senescence-accelerated mouse prone 8 mice
Shigeru Katayama*, Chizuru Okahata, Masashi Onozato, Takaaki Minami, Masanaga Maeshima, Shinya Yamazaki, Kazuaki Ogihara, Yuta Takahashi, Soichiro Nakamura
Nutrients, 14(13), 2708, Jun. 2022 - Maillard reaction products derived from heat-dried green tomato increase longevity and neuroprotection in Caenorhabditis elegans
Abdel Fawaz Bagoudou, Kanako Matsumoto, Supatta Chawalitpong, Hyun Young Park, Dhiraj A. Vattem, Soichiro Nakamura, Shigeru Katayama*
Food Science and Technology Research, 27(5), Sep. 2021, Refereed
Corresponding - Glochidion littorale Leaf Extract Exhibits Neuroprotective Effects in Caenorhabditis elegans via DAF-16 Activation
Abdel Fawaz Bagoudou, Yifeng Zheng, Masahiro Nakabayashi, Saroat Rawdkuen, Hyun-Young Park, Dhiraj A. Vattem, Kenji Sato, Soichiro Nakamura, Shigeru Katayama
MOLECULES, 26(13), 3958, Jun. 2021 - Hydrolysate of highly digestible phosphorylated buckwheat major allergen Fag e 2 attenuates allergic reactions in Fag e 2-sensitized mice
Ahmad M. Al Athamneh, Yuta Suzuki, Soichiro Nakamura, Shigeru Katayama
Japanese Journal of Food Chemistry and Safety, 27(2), 67-75, Aug. 2020, Refereed
Corresponding - Oral administration of okara soybean by-product attenuates cognitive impairment in a mouse model of accelerated aging
H.M. Corpuz, M. Arimura, S. Chawalitpong, K. Miyazaki, M. Sawaguchi, S. Nakamura, S. Katayama*
Nutrients, Dec. 2019, Refereed
Corresponding - Intracellular cAMP contents regulate NAMPT expression via induction of C/EBPβ in adipocytes
T. Mitani, S. Watanabe, K. Wada, H. Fujii, S. Nakamura, S. Katayama
Biochemical and biophysical research communications, Nov. 2019 - Preparation of an allergen-specific immunomodulator by phosphorylation of a major buckwheat globulin allergen, Fag e 1, with diminished IgE response via Tfh cell activation
Ahmad M. Al Athamneh, Supatta Chawalitpong, Yuta Suzuki, Daiki Yamaguchi, Soichiro Nakamura, Shigeru Katayama
Japanese Journal of Food Chemistry and Safety, 26(2), 91-98, Aug. 2019, Refereed - Adzuki bean (Vigna angularis) extract reduces amyloid- beta aggregation and delays cognitive impairment in Drosophila models of Alzheimer's disease
Miyazaki, H; Okamoto, Y; Motoi, A; Watanabe, T; Katayama, S; Kawahara, S; Makabe, H; Fujii, H; Yonekura, S
NUTRITION RESEARCH AND PRACTICE, 13(1), 64-69, Feb. 2019 - Oral immunotherapy with a phosphorylated hypoallergenic allergen ameliorates allergic responses more effectively than intact allergen in a murine model of buckwheat allergy
S. Katayama, D. Yamaguchi, Y. Suzuki, A.M. Al Athamneh, T. Mitani, R. Satoh, R. Teshima, Y. Mine, S. Nakamura
Molecular Nutrition & Food Research, 62(21), e1800303, Sep. 2018 - Long-term diet supplementation with Lactobacillus paracasei K71 prevents age-related cognitive decline in senescence-accelerated mouse prone 8
Henry M. Corpuz, Saki Ichikawa, Misa Arimura, Toshihiro Mihara, Takehisa Kumagai, Takakazu Mitani, Soichiro Nakamura, Shigeru Katayama*
Nutrients, 10(6), E762, Jun. 2018 - Theophylline suppresses interleukin-6 expression by inhibiting glucocorticoid receptor signaling in pre-adipocytes
Mitani T, Takaya T, Harada N, Katayama S (corresponding author), Yamaji R, Nakamura S, Ashida H
Archives of Biochemistry and Biophysics, 646, 98-106, Apr. 2018 - Soybean-derived glycine-arginine dipeptide administration promotes neurotrophic factor expression in the mouse brain
Shimizu, A., Mitani, T., Tanaka, S., Fujii, H., Maebuchi, M., Amiya, Y., Tanaka, M., Matsui, T., Nakamura, S., Katayama, S.
Journal of Agricultural and Food Chemistry, 66(30), 7935-7941, 2018 - Cyperenoic acid suppresses osteoclast differentiation and delays bone loss in a senile osteoporosis mouse model by inhibiting non-canonical NF-κB pathway
S., Chawalitpong, R., Chokchaisiri, A., Suksamrarn, S., Katayama, T., Mitani, S., Nakamura, A., AI Athamneh, P., Ritprajak, A., Leelahavanichkul, R., Aeimlapa, N., Charoenphandhu, T., Palaga
SCIENTIFIC REPORTS, 8, 5625, 2018 - Intestinal immunomodulatory effects of a hypoallergenic buckwheat Fag e 1 prepared by Maillard-type glycation with a mannan type-polysaccharide
Katayama, S., Tazawa, S., Kassai, M., Mitani, T., Nakamura, S.
Japanese Journal of Food Chemistry and Safety, 23(2), 72-79, 2016, Refereed - Improvement of surface functionalities including attenuation of allergenicity of whole buckwheat protein fraction by Maillard-type glycation with dextran.
Tazawa S, Katayama S, Hirabayashi M, Yamaguchi D, Nakamura S.
Preventive Nutrition and Food Science, 19(4), 327-332, 2014
MISC
Books and other publications
- ペプチドの生体調節機能と応用
シーエムシー出版, 23 Jul. 2024キクイモクロロゲン酸誘導体の花粉症軽減効果,花粉症等アレルギー疾患予防食品の開発
片山茂
シーエムシー出版, 2021Phytopharmaceuticals for Brain Health
Katayama, S., Nakamura, S., Modulation of neuroprotective genes by bioactivefood components in senescence-accelerated mice
CRC Press, 323-332 2017Bioactive Proteins and Peptides as Functional Foods and Nutraceuticals
Nakamura, S., Owaki, T., Maeda, Y., Katayama, S., Nakamura, K., Amyloidogenic proteins and peptides
101-120 2010Functional Foodand Health
Mine, Y., Katayama, S., Antioxidative stress peptides
213-228 2008
ISBN:9780841269828Lectures, oral presentations, etc.
- Brain health benefits by natural dietary bioactive compounds: a mechanistic exploration (Invited)
Katayama, S.
KSABC2016 (Jeju, Korea), 2016Effects of soy peptides on cognitive performance in senescence-accelerated mice and elderly people
S Katayama, A Shimizu, T Mitani, M Maebuchi, S Nakamura
ISNFF2016 (Florida, USA), 2016Modulation of neuroprotective genes by natural dietary bioactive compounds in senescence-accelerated mice
Katayama, S.
Pacifichem 2015 (Hawaii, USA), 2015Anti-aging effects of kale (Brassica oleracea) in senescence-accelerated mice (Invited)
Katayama, S., Kushimoto, S., Suto, Y., Nakamura, S.
ICAAI2014 (Cheng Rai, Thailand), 2014Neurotrophic effects of soy peptides in senescence-accelerated mice
Katayama, S., Maebuchi, M., Ishijima, T., Nakai, Y., Abe, K., Nakamura, S.
IUFoST2014 (Montreal, Canada), 2014Development of human dendritic cell-based in vitro assays for assessment of the potential allergenicity of foods and its anti-allergic compounds
Katayama, S., Kukita, T., Nakamura, S.
ISNFF2012 (Hawaii, USA), 2012Immunomodulatory properties enhanced by highly viscous polysaccharides from the brown alga Gagome (Kjellmaniella crassifolia) (Invited)
Katayama, S.
KosFost 2011 (Daegu, Korea), 2011Research Themes
- 認知症予防の新機軸:植物由来エクソソームの脂質解析に基づく脳移行性ナノ粒子の創製
挑戦的研究(萌芽)
27 Jun. 2025 - 31 Mar. 2028 - 免疫寛容誘導作用を有する低アレルゲン性蕎麦抗原ペプチドの創製と予防治療への応用
ニッポンハム食の未来財団
2017 - IgA産生促進作用を有するリン酸化蕎麦アレルゲンの創製とその応用
ニッポンハム食の未来財団
2016 - 樹状細胞の成熟化を指標とした食物アレルゲン性評価法の確立
清水純夫研究助成基金
2015 - 樹状細胞のHLA-DR発現応答を指標とした食物アレルゲン性評価法の開発
ホクト生物科学振興財団
2015 - Nrf2遺伝子を標的にした大豆サポニンの抗酸化ストレス作用とアミノ酸の相乗効果
不二たん白質研究振興財団
2009