TANIGUCHI SHUNICHIRO
School of Medicine Department of Biochemistry and Molecular Biology
Specially-appointed Professor
Researcher Information
Field Of Study
TEL
- 81-263-37-2679
Mail Address
- stangch★shinshu-u.ac.jp
Research activity information
Paper
- Activation of the inflammasome drives peritoneal deterioration in a mouse model of peritoneal fibrosis.
Kadoya H, Hirano A, Umeno R, Kajimoto E, Iwakura T, Kondo M, Wada Y, Kidokoro K, Kishi S, Nagasu H, Sasaki T, Taniguchi S, Takahashi M, Kashihara N.
FASEB J., 37(9), e23129, Sep. 2023, Refereed
- Endothelial Dysfunction Accelerates Impairment of Mitochondrial Function in Ageing Kidneys via Inflammasome Activation.
Wada Y, Umeno R, Nagasu H, Kondo M, Tokuyama A, Kadoya H, Kidokoro K, Taniguchi S, Takahashi M, Sasaki T, Kashihara N.
Int J Mol Sci., 22(17), 9269, Aug. 2021, Refereed - Potentiated antitumor effects of APS001F/5-FC combined with anti-PD-1 antibody in a CT26 syngeneic mouse model.
Shioya K, Matsumura T, Seki Y, Shimizu H, Nakamura T, Taniguchi S.
Biosci Biotechnol Biochem., 85(2), 324-331, Feb. 2021, Refereed
Last, Corresponding - In Situ Delivery and Production System (iDPS) of Anti-Cancer Molecules with Gene-Engineered Bifidobacterium
Taniguchi S
J Pers Med, 11(6), 2021 - Cecal Tumorigenesis in Aryl Hydrocarbon Receptor-Deficient Mice Depends on Cecum-Specific Mitogen-Activated Protein Kinase Pathway Activation and Inflammation
Matoba H, Takamoto M, Fujii C, Kawakubo M, Kasuga E, Matsumura T, Natori T, Misawa K, Taniguchi S, Nakayama J
Am J Pathol, 190(2), 453-468, 2020 - IL-1β Plays an Important Role in Pressure Overload-Induced Atrial Fibrillation in Mice
Matsushita N, Ishida N, Ibi M, Saito M, Takahashi M, Taniguchi S, Iwakura Y, Morino Y, Taira E, Sawa Y, Hirose M.
Biol Pharm Bull, 42(4), 543-546, 2019 - Bidirectional crosstalk between neutrophils and adipocytes promotes adipose tissue inflammation
Watanabe Y, Nagai Y, Honda H, Okamoto N, Yanagibashi T, Ogasawara M, Yamamoto S, Imamura R, Takasaki I, Hara H, Sasahara M, Arita M, Hida S, Taniguchi S, Suda T, Takatsu K.
FASEB J, 33(11), 11821-11835, 2019 - The eNOS-NO pathway attenuates kidney dysfunction via suppression of inflammasome activation in aldosterone-induced renal injury model mice
Sogawa Y, Nagasu H, Itano S, Kidokoro K, Taniguchi S, Takahashi M, Kadoya H, Satoh M, Sasaki T, Kashihara N
PLOS ONE, 13(10), e0203823, 2018 - Potential Role of ASC, a Proapoptotic Protein, for Determining the Cisplatin Susceptibility of Lung Cancer Cells
Sakaizawa T, Matsumura T, Fujii C, Hida S, Toishi M, Shiina T, Yoshida K, Hamanaka K, Ito KI, Taniguchi S
Tohoku J Exp Med, 244(2), 133-144, 2018 - Fascin1 Suppresses RIG-I-like Receptor Signaling and Interferon-β Production by Associating with IκB Kinase ϵ (IKK ϵ) in Colon Cancer
Matsumura T, Hida S, Kitazawa M, Fujii C, Kobayashi A, Takeoka M, Taniguchi SI, Miyagawa SI
J Biol Chem, 293(17), 6326-6336, 2018 - In situ delivery and production system of trastuzumab scFv with Bifidobacterium
Kikuchi T, Shimizu H, Akiyama Y, Taniguchi S
Biochem Biophys Res Commun, 493(1), 306-312, 2017 - ASC Induces Apoptosis via Activation of Caspase-9 by Enhancing Gap Junction-Mediated Intercellular Communication
Kitazawa M, Hida S, Fujii C, Taniguchi S, Ito K, Matsumura T, Okada N, Sakaizawa T, Kobayashi A, Takeoka M, Miyagawa S
PLOS ONE, 12(1), e0169340, 2017 - The endothelial adrenomedullin-RAMP2 system regulates vascular integrity and suppresses tumour metastasis.
Tanaka M, Koyama T, Sakurai T, Kamiyoshi A, Ichikawa-Shindo Y, Kawate H, Liu T, Xian X, Imai A, Zhai L, Hirabayashi K, Owa S, Yamauchi A, Igarashi K, Taniguchi S, Shindo T.
Cardiovasc Res., 2016 - Novel role of ASC as a regulator of metastatic phenotype.
Okada N, Fujii C, Matsumura T, Kitazawa M, Okuyama R, Taniguchi S, Hida S.
Cancer Med., 2016 - Role of NLRP3 Inflammasomes for Rhabdomyolysis-induced Acute Kidney Injury.
Komada T, Usui F, Kawashima A, Kimura H, Karasawa T, Inoue Y, Kobayashi M, Mizushina Y, Kasahara T, Taniguchi S, Muto S, Nagata D, Takahashi M.
Sci Rep., 2015 - Nanosilica-induced placental inflammation and pregnancy complications: Different roles of the inflammasome components NLRP3 and ASC.
Shirasuna1 K, Usui F , Karasawa T, Kimura H, Kawashima A, Hiroaki Mizukami H, Ohkuchi A, Nishimura S, Sagara J, Noda T, Ozawa K, Taniguchi S, Takahashi M
Nanotoxicology, 9(5), 554-567, 2015 - NFκB2 gene as a novel candidate that epigenetically responds to interval walking training.
Zhang Y, Hashimoto S, Fujii C, Hida S,Ito K, Matsumura T, Sakaizawa T, Morikawa M, Masuki S, Nose H, Higuchi K, Nakajima K, Taniguchi S
Int J Sports Med., 36(9), 769-775, 2015 - Inflammasome activation by mitochondrial oxidative stress in macrophages leads to the development of angiotensin Ⅱ-induced aortic aneurysm.
Usui F, Shirasuna K, Kimura H, Tatsumi K, Kawashima A, Karasawa T, Yoshimura K, Aoki H, Tsutsui H, Noda T, Sagara J, Taniguchi S, Takahashi M
Arterioscler Thromb Vasc Biol., 35(1), 127-136, 2015 - NLRP3 deficiency improves angiotensin II-induced hypertension but not fetal growth restriction during pregnancy.
Shirasuna K, Karasawa T, Usui F, Kobayashi M, Komada T, Kimura A, Ohkuchi A, Taniguchi S, Takahashi M.
Endocrinology, 156(11), 4281-4292, 2015 - Excess aldosterone is a critical danger signal for inflammasome activation in the development of renal fibrosis in mice.
Kadoya H, Satoh M, Sasaki T, Taniguchi S, Takahashi M, Kashihara N
The FASEB Journal, 29, 3899-3910, 2015 - ASC in Renal Collecting Duct Epithelial Cells Contributes to Inflammation and Injury after Unilateral Ureteral Obstruction.
Komada T, Usui F, Shirasuna K, Kawashima A, Kimura H, Karasawa T, Nishimura S, Sagara J, Noda T, Taniguchi S, Muto S, Nagata D, Kusano E, Takahashi M
AMERICAN JOURNAL OF PATHOLOGY, 184(5), 1287-1298, 2014 - NLRP3 Regulates Neutrophil Functions and Contributes to Hepatic Ischemia-Reperfusion Injury Independently of Inflammasomes
Inoue Y, Shirasuna K, Kimura H, Usui F, Kawashima A, Karasawa T, Tago K, Dezaki, Nishimura S, Sagara J, Noda T, IwakuraY, Hiroko Tsutsui H, Taniguchi S, Yanagisawa K, Yada T, Yasuda Y, Takahashi M.
J Immunol, 192(9), 4342-4351, 2014 - ビフィズス菌を用いた抗がん剤開発
谷口俊一郎
BIO INDUSTRY, 31(5), 43-48, 2014 - Phactr3/scapinin, a member of protein phosphatase 1 and actin regulator (phactr) family, interacts with the plasma membrane via basic and hydrophobic residues in the N-terminus.
Itoh A, Uchiyama A, Taniguchi S, Sagara J
PLOS ONE, 9(11), e113289, 2014 - Effect of a cholesterol-rich lipid environment on the enzymatic activity of reconstituted hyaluronan synthase
Pawared Ontong, Hatada Y, Taniguchi S, Kakizaki I, Itano N
Biochem. BiophysResCommun, 443, 666-671, 2014 - Nucleic acid sensing by T cells initiates Th2 cell differentiation.
Imanishi T, Ishihara C, Badr Mel S, Hashimoto-Tane A, Kimura Y, Kawai T, Takeuchi O, Ishii KJ, Taniguchi S, Noda T, Hirano H, Brombacher F, Barber GN, Akira S, Saito T
Nat Commun, 10, 3566, 2014 - ビフィズス菌を利用した固形がん治療の試み
谷口俊一郎
Japanese Journal of Lactic Acid Bacteria, 25, 1, 2014 - ASC-associated inflammation promotes cecal tumorigenesis in aryl hydrocarbon receptor- deficient mice.
Ikuta T, Kobayashi Y, Kitazawa M, Shiizaki K, Itano N, Noda T, Pettersson S, Poellinger L, Fujii-Kuriyama Y, Taniguchi S, Kawajiri K.
Carcinogenesis., 34(1), 1620-1627, 2013 - Clinical significance of apotosis-associated speck-like protein containing a caspase recruitment domain in oral squamous cell carcinoma.
Shimane T, Kobayashi H, Takeoka M, Kitazawa M, Matsumura T, Hida S, Tiepeng Xiao, Koike T, Taniguchi S, Kurita H.
Oral&Maxillofacial Pathology, 115(6), 799-809, 2013 - Beneficial innate signaling interference for antibacterial responses by a Toll-like receptor- mediated enhancement of the MKP-IRF3 axis.
Negishi H, Matsuki K, Endo N, Sarashina H, Miki S, Matsuda A, Fukazawa K, Taguchi-Atarashi N, Ikushima H, Yanai H, Nishio J, Honda K, Fujioka Y, Ohba Y, Noda T, Taniguchi S, Nishida E, Zhang Y, Chi H, Flavell RA, Taniguchi T.
Proc Natl Acad SciU SA, 110(49), 19884-19889, 2013 - Crucial Role of Hyaluronan in Neointimal Formation after Vascular Injury.
Kashima Y, Takahashi M, Shiba Y, Itano N, Izawa A, Koyama J, Nakayama J, Taniguchi S, Kimata K, Ikeda U.
PLoS One., 8(3), e58760, 2013 - Critical role of caspase-1 in vascular inflammation and development of atherosclerosis in Western diet-fed apolipoprotein E-deficient mice.
Usui F, Shirasuna K, Kimura H, Tatsumi K, Kawashima A, Karasawa T, Hida S, Sagara J, Taniguchi S,Takahashi M.
Biochem Biophys Res Commun., 425, 162-168, 2012 - Inflamasome Activation of Cardiac Fibroblasts IsEssential for MyocardialIschemia/Reperfusion Injury
Kawaguchi M, Takahashi M, Hata T, Kashima Y, Usui F, Izawa A, Takahashi Y, Masumoto J, Koyama J, Hongo M, Noda Tetsuo, Nakayama J, Sagara J, Taniguchi S, Ikeda U.
Circulation., 123, 594-604, 2011 - A novel role of Rho-kinase in the regulation of ligand-induced phosphorylated EGFR endocytosis via the early/late endocytic pathway in human fibrosarcomacells.
Nishimura Y, Biborka Bereczky, Yoshioka K, Taniguchi S, Itoh K
J Mol Histol., 42, 427-442, 2011 - ASC plays a role in the priming phase of the immune response to type II collagen in collagen-induced arthritis.
Yamazaki H, Takeoka M, Kitazawa M, Ehara T, Itano N, Kato H, Taniguchi S.
Rheumatol Int., Feb 18, Epub ahead of print, 2011 - Hyaluronan Deficiency in Tumor Stroma Impairs Macrophage Trafficking and TumorNeovascularization.
Kobayashi N, Miyoshi S, Mikami T, Koyama H, Kitazawa M, Takeoka M, Sano K,Amano J, Isogai Z, Niida S, Oguri K, Okayama M, John A. McDonald, Kimata K, Taniguchi S, Itano N.
Cancer Res., 70(18), 7073-7083, 2010 - Calponin h1-S175T Point Mutation Enhances Resistance to Actin Cytoskeleton Perturbation in Human CancerCells
Sugaya A, Takeoka M, Itano N, Taguchi A, Ehara T, Taniguchi S.
Anticancer Res., 30, 1071-1078, 2010 - Anti-inflammatory activity of PYNOD and its mechanism in humans and mice.
Imamura R, Wang Y, Kinoshita T, Suzuki M, Noda T, Sagara J, Taniguchi S, Okamoto H, Suda T.
J Immunol., 184(10), 5874-5884, 2010 - Pathogenic Vibrio activated NLRP3 inflammasome via cytotoxins and TLR/NOD-Mediated NF-κB signaling.
Toma C, Higa N, Koizumi Y, Nakasone N, Ogura Y, McCoy AJ, Franchi L, Uematsu S, Sagara J, Taniguchi S, Tsutsui H, Akira S, Tschopp J, Núñez G, Suzuki T.
J. Immunol., 184(9), 5287-5297, 2010 - Effects of Anti-CD70 mAb on Theiler’s Murine Encephalomyelitis Virus-Induced Demyelinaiting Disease.
Yanagisawa S, Takeichi N, Kaneyama T, Yagita H, Taniguchi S, Byung S.Kim, Chang-Sung Koh
Brain Res., 4, 236-245, 2010 - Targeting solid tumors with non-pathogenic obligate anaerobic bacteria.
Taniguchi S, Fujimori M, Sasaki T, Tsutsui H, Shimatani Y, Seki K, Amano J.
Cancer Sci., 101(9), 1925-1932, 2010 - Exercise Effects on Methylation of ASC Gene.
Nakajima K, Takeoka M, Mori M, Hashimoto S, Sakurai A, Nose H, Higuchi K, Itano N,Shiohara M, Oh T, Taniguchi S.
IntJ Sports Med., 31(9), 671-675, 2010
- Contribution of TIR domain-containing adapter inducing IFN-β mediated IL-18 Release to LPS-induced liver injury in mice.
Imamura M, Tsutsui H, Yasuda K, Yumikura-Futatsugi S, Mitani K, Uchiyama R, Hayashi S, Akira S, Taniguchi S, Nico Van Rooijen, Jurg Tschopp,Yamamoto T, Fujimoto J, Nakanishi K.
51, 333-341, 2009 - Role of ASC in the Mouse Model ofHelicobacter pylori Infection.
Benoit BN, Kobayashi M, Kawakubo M,Takeoka M, Sano K, Zou J, Itano N, Tsutsui H, Noda T, Fukuda M, Nakayama J, Taniguchi S
J.Histochem&Cytochem., 57(4), 327-338, 2009 - Scapinin, the Protein Phosphatase 1 Binding Protein, Enhances Cell Spreading and Motility by Interacting with the Actin Cytoskeleton
Sagara J, Arata T, Taniguchi S
PLOS ONE, 4(1), e4247, 2009 - A Splice Variant of ASC Regulates IL-1β Release and Aggregates Differently from Intact ASC.
Matsushita K, Takeoka M, Sagara J, Itano N, Kurose Y, Nakamura A, Taniguchi S.
Mediators Inflamm., 2009, 287387, 2009 - Metastasis-associated gene expression profile of liver and subcutaneous lesions derived from mouse pheochromocytoma cells.
Ohta S, Taniguchi S, et al
Molecular Carcinogenesis, 47, 245-251, 2008 - Significance of Tumor-Associated Stroma in Promotion of Intratumoral Lymphangiogenesis: Pivotal Role of a Hyaluronan-Rich Tumor Microenvironment
Koyama H, Kobayashi N, Harada M, Takeoka M, Kawai Y, Sano K, Fujimori M, Amano, J., Ohhashi, T., Kannagi, R., Kimata, K., Taniguchi, S., and Itano, N.
Am. J. Pathol, 172, 179-193, 2008 - Reduction of Calponin h1 expression in human colon cancer blood vessels
Yanagisawa Y, Takeoka M, Ehara T, Itano N, Miyagawa S, Taniguchi S.
European Journal of Surgical Oncology, 34, 531-537, 2008 - Critical role of bone marrow apoptosis-associated speck-like protein, an inflammasome adaptor molecule, in neointimal formation after vascular injury inmice
Yajima N, Takahashi M, Morimoto H, Shiba Y, Takahashi Y, Masumoto J, Ise H,Sagara J, Nakayama J, Taniguchi S, Ikeda U
Circulation., 117(24), 3079-3087, 2008 - Hyperproduction of Hyaluronan in Neu-Induced Mammary Tumor Acceletrates Angiogenesis through Stromal Cell Recruitment: Possible Involvement of Versican/PG-M.
KoyamaH; Hibi T； Isogai Z； Yoneda M；Fujimori M; Amano J; Kawakubo M; Kannagi R；Kimata K；Taniguchi S；Itano N.
Am. J.Pathol., 170(3), 1086-1099, 2007 - Translocation of Heparanase into Nucleus Results in Cell Differentiation.
Nobuhisa T, Nakamoto Y, Okawa T, Takaoka M, Gundz M, Nagatsuka H, Tsujigiwa H, Shirakawa Y, Yamatsuji T, Haisa M, , Matsuoka J, Nakajima M, Taniguchi S, Sagara J, Dong J, and Tanaka N.
Cancer Sci., 98(4), 535-540, 2007 - Strong Enhancement of Recombinant Cytosine Deaminase Activity in Bifidobacterium longum for Tumor Targeting Enzyme-Prodrug Therapy.
Hamaji Y, Fujimori M, Sasaki T, MatsuhashiH, Matsui-Seki K, Shimatani-Shibata Y, Kano Y, Amano J, and Taniguchi S.
Biosci. Biotechnol Biochem, 71(4), 874-883, 2007 - In vitro expression of β-thalassemia gene(IVS1-1G>C) reveals complete inactivation of the normal5 splice site and alternative aberrant RNA splicing.
Fujihara N, Yamauchi K, Hirota-Kawadobora M,Ishikawa S,Tozuka M, Ishii E, Katsuyama T, Nobuo Okumura, Taniguchi S
Ann Clin Biochem., 44(6), 573-578, 2007 - Development of spontaneous optic neuropathy in NF-kBp50-deficient mice; Requirement for NF-kBp50 in ganglion cell survival
Takahashi Y, Katai N, Murata T, Taniguchi S, Hayashi T
Neuropath, Applied Neurobiol., 33(6), 692-705, 2007 - Regulatory molecules involved in inflammasome formation with special reference toa key mediator protein, ASC
Taniguchi S, SagaraJ
Semin Immunopathol, 29(3), 231-238, 2007 - Exogeneous cytosine deaminase gene expression in bifidobacterium breve Ⅰ-53-8w for tumor-targeting enzyme/prodrug therapy
Hidaka A, Hamaji Y, Sasaki T, Taniguchi S, Fujimori M.
Biosci. Biotechnol. Biochem., 71(12), 2921-2926, 2007 - Crosstalk between neovessels and mural cells directs the site-specific expression of
Yana I, Sagara H, Takaki S, Takatsu K, Nakamura K, Nakao K, Katsuki M, Taniguchi S, Aoki T, Sato H, Weiss SJ, Seiki M.
J. Cell Sci., 120(9), 1607-1614, 2007 - Genetically engineered bifidobacterium longum for tumor-targeting enzyme-prodrug therapy of breast cancer.
Fujimori, M; Sasaki, T; Hamaji, Y; Amano, J; Taniguchi, S
BREAST CANCER RESEARCH ANDTREATMENT, 100, S77-S77, 2006 - Animal models of pheochromocytoma including NIH initial experience
Ohta, S; Lai, EW; Taniguchi, S; Tischler, AS; Alesci, S; Pacak, K
PHEOCHROMOCYTOMA, 1073, 300-305, 2006 - Adenovirus-mediated Calponin h1 gene therapy directed against peritoneal dissemination of ovarian cancer: Bifunctional therapeutic effects on peritoneal cell layer and cancer cells
Ogura, T; Kobayashi, H; Ueoka,Y; Okugawa, K; Kato, K; Hirakawa, T; Hashimoto, S; Taniguchi, S; Wake, N;Nakano,H
CLINICAL CANCER RESEARCH, 12(17), 5216-5223, 2006 - Hypermethylation of ASC/TMS1 is a sputum marker for late-stage lung cancer
Machida, EO; Brock, MV; Hooker, CM; Nakayama, J; Ishida, A; Amano, J; Picchi, MA; Belinsky, SA; Herman, JG; Taniguchi, S; Baylin, SB
CANCER RESEARCH, 66(12), 6210-6218, 2006 - Genetically engineered Bifidobacterium longum for tumor-targeting enzyme-prodrug therapy of autochthonous mammary tumors in rats
Sasaki, T; Fujimori, M; Hamaji, Y; Hama, Y; Ito, K; Amano, J; Taniguchi, S
CANCER SCIENCE, 97(7), 649-657, 2006 - Cryopyrin and pyrin activate caspase-1, but not NF-kappa B, via ASC oligomerization
Yu, JW; Wu, J; Zhang, Z; Datta, P; Ibrahimi, I; Taniguchi, S; Sagara, J; Fernandes-Alnemri, T; Alnemri, ES
CELL DEATH AND DIFFERENTIATION, 13(2), 236-249, 2006 - QT PRODACT: a multi-site study of in vitro action potential assays on 21 compounds in isolated guinea-pig papillary muscles
Hayashi S, Kii Y, Tabo M, Fukuda H, Itoh T, Shimosato T, Amano H, Saito M, Morimoto H, Yamada K, Kanda A, Ishitsuka T, Yamazaki T, Kiuchi Y, Taniguchi S, Mori T, Shimizu S, Tsurubuchi Y, Yasuda S, Kitani S, Shimada C, Kobayashi K, Komeno M, Kasai C, Hombo T, Yamamoto K
J Pharmacol Sci, 99, 423-437, 2005 - QT PRODACT: evaluation of the potential of compounds to cause QT interval prolongation by action potential assays using guinea-pig papillary muscles
Kii Y, Hayashi S, Tabo M, Shimosato T, Fukuda H, Itoh T, Amano H, Saito M, Morimoto H, YamadaK, Kanda A, Ishitsuka T,Yamazaki T, Kiuchi Y, Taniguchi S, Mori T, Shimizu S, Tsurubuchi Y, Yasuda S, Kitani S, Shimada C, Kobayashi K, Komeno M, Kasai C, Hombo T, Yamamoto K
J Pharmacol Sci, 99, 449-457, 2005 - 特発性大腿骨頭壊死症におけるグルココルチコイド受容体の遺伝子多型性解析
堀内博志，五明広樹，中島滋郎，若林真司，斎藤直人，小林千益，縄田昌司，橋本博史，津田裕士，深沢 徹，谷口俊一郎，高岡邦夫
別冊整形外科, 48, 51-53, 2005 - インターロイキン18(IL--)ーその作用と活性化機序
谷口俊一郎
信州医誌, 53, 33-34, 2005 - Dihydropyrimidine dehydrogenase expressionpredicts survival outcome and chemosensitivity to 5-fluorouracil in patients with oral squamous cell carcinoma
Kobayashi H, Koike T, Nakatsuka A, Kurita H, Sagara J, Taniguchi S, Kurashina K
Oral Oncol, 41(1), 38-47, 2005 - Role of charged and hydrophobic residues in the oligomerization of the PYRIN domain of ASC
Moriya M, Taniguchi S, Peter Wu, Edvards Liepinsh, Gottfried Otting, Sagara J
Biochemistry, 44(2), 575-583, 2005 - Suppression of cancer phenotypes through a multifunctional actin-binding protein, calponin, that attacks cancer cells and simultaneously protects the host from invasion
Taniguchi, S
CANCER SCIENCE, 96(11), 738-746, 2005 - 新規アポトーシス制御蛋白ASC：インターロイキン変換酵素の新しい活性化経路
相良淳ニ，谷口俊一郎
臨床免疫, 42(3), 306-312, 2004 - Clinical significance of cellular distribution of moesin in patients with oral squamous cell carcinoma
Kobayashi H, Sagara J, Kurita H, Morifuji M, Ohishi M, Kurashina K, Taniguchi S
Clin Cancer Res, 10(2), 572-580, 2004 - Selective expression and functional characteristics of three mammalian hyaluronan synthases in oncogenic malignant transformation
Itano N, Sawai T, Atsumi F, Miyaishi O, Taniguchi S, Kannagi R, Hamaguchi M, Kimata K
J Biol Chem, 279(18), 18679-18687, 2004 - ASC is essential for LPS-induced activation of procaspase-1 independently of TLR-associated signal adaptor molecules
Yamamoto M, Yaginuma K, Tsutsui H, Sagara J, Guan X, Seki E, Yasuda K, Yamamoto M,AkiraS, Nakanishi K, Noda T, Taniguchi S
Genes to Cells, 9(11), 1055-1067, 2004 - Scapinin, a putative protein phosphatase-1 regulatory subunit associated with the nuclear nonchromatin structure
Sagara J, Higuchi T, Hattori Y, Moriya M, Sarvotham H, Shima H, Shirato H, KikuchiK,Taniguchi S
J Biol Chem, 278(46), 45611-45619, 2003 - Methylation of ASC/TMS1, a proapoptotic gene responsible for activating procaspase-1, in human colorectal cancer
Yokoyama, T; Sagara, J; Guan, X; Masumoto, J; Takeoka, M; Komiyama, Y; Miyata, K; Higuchi, K; Taniguchi, S
Cancer Letters, 202(1), 101-108, 2003 - Impaired arterial pressure regulation during exercise dueto enhanced muscular vasodilatation in calponin knockout mice
Masuki, S; Takeoka, M; Taniguchi, S; Yokoyama, M; Nose, H
JOURNAL OF PHYSIOLOGY-LONDON, 553(1), 203-212, 2003 - Suppression of peritoneal dissemination through protecting mesothelial cells from retraction by cancer cells
Hashimoto, S; Takeoka, M; Taniguchi, S
INTERNATIONAL JOURNAL OF CANCER, 107(4), 557-563, 2003 - ASC/TMS1, A caspase-1 activating adaptor, is downregulated by aberrant methylation in human melanoma
Guan, X; Sagara, J; Yokoyama, T; Koganehira, Y; Oguchi, M; Saida, T; Taniguchi, S
INTERNATIONAL JOURNAL OF CANCER, 107(2), 202-208, 2003 - Reduced expression of actin-binding proteins, h-caldesmon and calponin h1, in the vascular smooth muscle inside melanoma lesions: an adverse prognostic factor for malignant melanoma
Koganehira, Y; Takeoka, M; Ehara, T; Sasaki, K; Murata, H; Saida, T; Taniguchi, S
BRITISH JOURNAL OF DERMATOLOGY, 148(5), 971-980, 2003 - Shifts in cellular localization of moesin in normal oral epithelium, oral epithelial dysplasia, verrucous carcinoma and oral squamous cell carcinoma
Kobayashi, H; Sagara, J; Masumoto, J; Kurita, H; Kurashina, K; Taniguchi, S
JOURNAL OF ORAL PATHOLOGY&MEDICINE, 32(6), 344-349, 2003 - Impaired arterial pressure regulation during exercise due to enhancedmuscular vasodilation in calponin knockout mice
Masuki, S; Takeoka, M; Taniguchi, S; Nose, H
FASEB JOURNAL, 17(4), A431-A431, 2003 - ASC is an activating adaptor for NF-kappa B and caspase-8-dependent apoptosis
Masumoto, J; Dowds, TA; Schaner, P; Chen, FF; Ogura, Y; Li, M; Zhu, L; Katsuyama, T; Sagara, J; Taniguchi, S; Gumucio, DL;Nunez, G; Inohara, N
Biochemical and biophysical research communications, 303(1), 69-73, 2003 - Enhanced baroreflex sensitivity in free-moving calponin knockout mice
Masuki, S; Takeoka, M; Taniguchi, S; Nose, H
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY, 284(3), H939-H946, 2003 - Caspy, a zebrafish caspase, activated by ASC oligomerization is required for pharyngeal arch development
Masumoto, J; Zhou, WB; Chen, FF; Su, FY; Kuwada, JY; Hidaka, E; Katsuyama,T; Sagara, J; Taniguchi, S;Ngo-Hazelett, P; Postlethwait, JH;Nunez, G; Inohara, N
JOURNAL OF BIOLOGICAL CHEMISTRY, 278(6), 4268-4276, 2003 - Increased locomotor activity, increased food and water intake and decreased PVN neurons in H1 calponin gene-deficient mice
Bannai, M; Yoshimoto, R; Mitsui-Saito, M; Hori, M; Nishihara, M; Takahashi, K; Yamamura, H; Taniguchi, S; Katsuki, M; Ozaki, H; Karaki, H
JOURNAL OF VETERINARYMEDICALSCIENCE, 65(1), 153-155, 2003 - H1カルポニン遺伝子欠損マウスにおける運動性ならびに摂食・飲水行動の増加(短報)(生理学)
坂内慎，善本亮，三井-斉藤みの里，堀正敏，西原真杉，高橋克仁，山村倫子，谷口俊一郎，勝木元也，尾崎博，唐木英明
The journal of veterinary medical science, 65(1), 153-155, 2003 - Calponin h1 suppresses tumor growth of src-induced transformed 3Y1 cells in association with a decrease in angiogenesis.
Kaneko M, Takeoka M, Oguchi M, Koganehira Y, MurataH, Ehara T, Tozuka M, Saida T, Taniguchi S
Jpn J Cancer Res, 93(8), 935-943, 2002 - ASC, which is composed of a PYD and a CARD, is up-regulated by inflammation and apoptosis in human neutrophils
Shiohara M, Taniguchi S, Masumoto J, Yasui K, Koike K, Komiyama A, Sagara J
Biochem Biophys Res Commun, 293(5), 1314-1318, 2002 - The genus Bifidobacterium for cancer gene therapy
Fujimori M, Amano J, Taniguchi S
Current Opinion In Drug Discovery&Development, 5(2), 200-203, 2002 - Cloned cytosine deaminase gene expression of bifidobacterium longum and application to enzyme/pro-drug therapy of hypoxic solid tumors
Nakamura T, Sasaki T, Fujimori M, Yazawa K, Kano Y, Amano J, Taniguchi S
Biosci Biotechnol Biochem, 66(11), 2362-2366, 2002 - Inhibition of urokinase-type plasminogen activator delays expression of c-jun, activated transforming growth factor beta 1, and matrix metalloproteinase 2 during post-hepatectomy liver regenerationin mice
Nomura K, Miyagawa S, Ayukawa K, Soeda J, Taniguchi S, Kawasaki S
J Hepatology, 36(5), 637-644, 2002 - Expression of lamins depends on epidermal differentiation and transformation
Oguchi M, Sagara J, Matsumoto K, Saida T, Taniguchi S
Brit.J. Dermatology, 147(5), 1-6, 2002 - Calponin H1 induced a flattened morphology and suppressed the growth of human fibrosasrcoma HT1080 cells
Takeoka M, Ehara T, Hashimoto S, Taniguchi S
Eur J Cancer, 38(3), 436-442, 2002 - Antitumor efficacy of anaerobic bacteria as delivery system for breast cancer gene therapy.
Fujimori, M; Sasaki, T; Nakamura, T; Amano, J; Taniguchi, S
Breast Cancer Research and Treatment, 76, S100-S100, 2002 - Apoptosis-associated speck-like protein is associated with inflammation and apoptosis in liver withhepatitis C infection.
Soeda, J; Miyagawa, S; Sagara, J; Sano, K; Masumoto, J; Ichikawa, E; Taniguchi, S; Kawasaki, S
Hepatology, 36(4), 270A-270A, 2002 - Structural fragility of blood vessels and peritoneum in calponin h1-deficientmice, resulting in an increase in hematogenous metastasis and peritoneal dissemination of malignant tumor cells
Taniguchi, S; Takeoka, M; Ehara, T; Hashimoto, S; Shibuki, H; Yoshimura, N; Shigematsu, H; Takahashi, K; Katsuki, M
CANCER RESEARCH, 61(20), 7627-7634, 2001 - ASC, which is composed of a pyrin-N-terminal homology domain and a caspase-recruitment domain, is up-regulated by inflammation and apoptosis in human neutrophils.
Shiohara, M; Taniguchi, S; Masumoto, J; Yasui, K; Koike, K; Komiyama, A; Sagara, J
BLOOD, 98(11), 229A-229A, 2001 - Bifidobacterium longum as a delivery system for gene therapy of chemically induced rat mammary tumors.
Fujimori, M; Nakamura, T; Sasaki, T; Hama, Y; Amano, J; Taniguchi, S
Breast Cancer Research and Treatment, 69(3), 256-256, 2001 - Dynamic DNA methylation change in the CpGisland region of p15 during human myeloid development
Sakashita, K; Koike, K; Kinoshita, T; Shiohara, M; Kamijo, T; Taniguchi, S; Kubota, T
JOURNAL OF CLINICAL INVESTIGATION, 108(8), 1195-1204, 2001 - Cytochrome c release into cytosol with subsequent caspase activation during warm ischemia in rat liver
Soeda, J; Miyagawa, S; Sano, K; Masumoto, J; Taniguchi, S; Kawasaki, S
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY, 281(4), G1115-G1123, 2001 - Initiation of apoptotic cascade during warm ischemia in rat liver.
Soeda, J; Miyagawa, S; Sano, K; Masumoto, S; Taniguchi, S; Kawasaki, S
Hepatology, 34(4), 275A-275A, 2001 - Urokinase-type plasminogen activator initiates expression of c-jun, activated transforming growth factor beta 1, and matrix metalloproteinase 2 during post-hepatectomy liver regeneration in mice.
Nomura, K; Miyagawa, S; Ayukawa, K; Soeda, J; Taniguchi, SI; Kawasaki, S
Hepatology, 34(4), 387A-387A, 2001 - Expression of apoptosis-associated speck-like protein containing a caspaserecruitment domain, a pyrin N-terminal homology domain-containing protein, in normal human tissues
Masumoto, J; Taniguchi, S; Nakayama, J; Shiohara, M; Hidaka, E; Katsuyama, T; Murase, S;Sagara, J
JOURNAL OF HISTOCHEMISTRY&CYTOCHEMISTRY, 49(10), 1269-1275, 2001 - Close relation of reduced expression of actin-binding proteins, calponin-h1 and h-caldesmon, in the vascular smoothmuscle inside human malignant melanoma with the poor prognosis
Koganehira, Y; Takeoka, T; Ehara, T; Hashimoto, S; Murata, H; Saida, T; Taniguchi,S
JOURNAL OF INVESTIGATIVE DERMATOLOGY, 117(2), 393-393, 2001 - Bifidobacterium longum as a delivery system for gene therapy of chemically induced rat mammary tumors
Yazawa, K; Fujimori, M; Nakamura,T; Sasaki, T; Amano, J; Kano, Y; Taniguchi, S
Breast Cancer Research and Treatment, 66(2), 165-170, 2001 - Pyrin N-terminal homology domain- and caspase recruitment domain-dependent oligomerization of ASC
Masumoto, J; Taniguchi, S; Sagara, J
Biochemical and biophysical research communications, 280(3), 652-655, 2001 - Murine ortholog of ASC, a CARD-containing protein, self-associates and exhibits restricteddistribution in developing mouse embryos
Masumoto, J; Taniguchi, S; Nakayama, K; Ayukawa, K; Sagara, J
EXPERIMENTAL CELL RESEARCH, 262(2), 128-133, 2001 - La autoantigen is cleaved in the COOH terminus and loses the nuclear localization signal during apoptosis
Ayukawa, K; Taniguchi, S; Masumoto, J; Hashimoto, S; Sarvotham, H; Hara, A;Aoyama, T; Sagara, J
JOURNALOF BIOLOGICAL CHEMISTRY, 275(44), 34465-34470, 2000 - Contractile properties and proteins of smooth muscles of a calponin knockout mouse
Matthew, JD; Khromov, AS; McDuffie, MJ; Somlyo, AV; Somlyo, AP; Taniguchi, S; Takahashi, K
JOURNAL OF PHYSIOLOGY-LONDON, 529(3), 811-824, 2000 - Ca2+-sensitization of contraction in the h1 calponin-deficient smooth muscle
Yoshimoto, R; Hori, M; Takahashi, K; Taniguchi, S; Katsuki, M; Ozaki, H; Karaki, H
JAPANESE JOURNAL OF PHARMACOLOGY, 84(4), 474-475, 2000 - Regulation of shortening velocity by calponin in intact contracting smooth muscles
Takahashi, K; Yoshimoto, R; Fuchibe, K; Fujishige, A; Mitsu-Saito, M; Hori, M; Ozaki, H; Yamamura, H; Awata, N; Taniguchi, S; Katsuki, M; Tsuchiya, T; Karaki, H
Biochemical and biophysical research communications, 279(1), 150-157, 2000 - Human malignant melanoma cells release a factor that inhibits the expressionof smooth muscle alpha-actin
Okamoto-Inoue, M; Nakayama, J; Hori, Y; Taniguchi, S
JOURNAL OF DERMATOLOGICAL SCIENCE, 23(3), 170-177, 2000 - Sequential chemoimmunotherapy with cisplatin, interferon-beta and interleukin-2 inhibits the growth of B16-F1 melanoma in syngeneic mice
Kubo, H; Matsumoto, K; Funahashi, M; Takagi, H; Kitajima, Y; Taniguchi, S; Saida, T
MELANOMA RESEARCH, 10(3), 223-229, 2000 - Bifidobacterium longum as a delivery system for cancer gene therapy: selective localization and growth in hypoxic tumors
Yazawa, K; Fujimori, M; Amano, J; Kano, Y; Taniguchi, S
CANCER GENE THERAPY, 7(2), 269-274, 2000 - Bifidobacterium longum as a delivery system for cancer gene therapy: selective localization and growth in hypoxic tumors
K Yazawa, M Fujimori, J Amano, Y Kano, S Taniguchi
CANCER GENE THERAPY, 7(2), 269-274, 2000 - ASC, a novel 22-kDa protein, aggregates during apoptosis of human promyelocytic leukemia HL-60 cells
Masumoto, J; Taniguchi, S; Ayukawa, K; Sarvotham, H; Kishino, T; Niikawa, N; Hidaka, E; Katsuyama, T; Higuchi, T; Sagara, J
JOURNAL OF BIOLOGICAL CHEMISTRY, 274(48), 33835-33838, 1999 - Possible role of calponin h1 as a tumor suppressor in human uterine leiomyosarcoma
Horiuchi, A; Nikaido, T; Taniguchi, S; Fujii, S
JOURNAL OF THE NATIONAL CANCER INSTITUTE, 91(9), 790-796, 1999 - Increased synthesis of hyaluronate enhances motility of human melanoma cells
Ichikawa, T; Itano, N; Sawai, T; Kimata, K; Koganehira, Y; Saida, T; Taniguchi, S
JOURNAL OF INVESTIGATIVE DERMATOLOGY, 113(6), 935-939, 1999 - Roxithromycin and clarithromycin, 14-membered ring macrolides, potentiate the antitumor activity of cytotoxic agents against mouse B16melanoma cells
Yatsunami, J; Fukuno, Y; Nagata, M; Tsuruta, N; Aoki, S; Tominaga, M; Kawashima, M; Taniguchi, S; Hayashi, S
Cancer Letters, 147(1-2), 17-24, 1999 - Antiangiogenic and antitumor effects of 14-membered ring macrolides on mouse B16 melanoma cells
Yatsunami, J; Fukuno, Y; Nagata, M; Tominaga, M; Aoki, S; Tsuruta, N; Kawashima, M; Taniguchi, S; Hayashi, S
CLINICAL&EXPERIMENTAL METASTASIS, 17(4), 361-367, 1999 - The induction of smooth muscle alpha actin in a transformed rat cell line suppresses malignant properties in vitro and in vivo
Okamoto-Inoue, M; Kamada, S; Kimura, G; Taniguchi, S
Cancer Letters, 142(2), 173-178, 1999 - Inhibitory effects of roxithromycin on tumor angiogenesis, growth and metastasis of mouse B16 melanoma cells
Yatsunami, J; Tsuruta, N; Fukuno, Y; Kawashima,M; Taniguchi, S; Hayashi, S
CLINICAL&EXPERIMENTAL METASTASIS, 17(2), 119-124, 1999 - Reduced expression of an actin binding protein, calponin h 1 (CNh1), in blood vessels of human malignant skin tumors
Koganehira, Y; Ehara, T; Takeoka, M; Saida, T; Taniguchi, S
JOURNAL OFINVESTIGATIVE DERMATOLOGY, 112(4), 569-569, 1999 - Promoted dermal fibrosis during wound healing in calponin h 1 (CNhl)-deleted mice
Takeoka, M; Ehara, T; Murata, H; Saida, T; Katsuki,M; Takahashi, K; Taniguchi, S
JOURNAL OF INVESTIGATIVE DERMATOLOGY, 112(4), 583-583, 1999 - Mice lackingsmooth muscle calponin display increased bone formation that is associated with enhancement of bone morphogenetic protein responses
Yoshikawa, H; Taniguchi, S; Yamamura, H; Mori, S; Sugimoto, M; Miyado, K; Nakamura, K; Nakao, K; Katsuki, M; Shibata, N; Takahashi, K
Genes to Cells, 3(10), 685-695, 1998 - Genomic structure of the human ribosomalprotein L41 gene
Go, H; Miyado, K; Taniguchi, S
BIOCHEMISTRY AND MOLECULAR BIOLOGY INTERNATIONAL, 46(6), 1227-1231, 1998 - Augmentation in the expression of a ribosomal protein associated with transformation
Go, H; Taniguchi, S
BIOCHEMISTRY AND MOLECULAR BIOLOGY INTERNATIONAL, 46(3), 629-638, 1998 - Reduced expression of calponin h1 in leiomyosarcoma of the uterus
Horiuchi, A; Nikaido, T; Ito, K;Zhai, YI; Orii, A; Taniguchi, S; Toki, T; Fujii, S
LABORATORY INVESTIGATION, 78(7), 839-846, 1998 - Expression of moesin and its associated molecule CD44 in epithelial skin tumors
Ichikawa, T; Masumoto, J; Kaneko, M; Saida, T; Sagara, J; Taniguchi, S
JOURNAL OF CUTANEOUS PATHOLOGY, 25(5), 237-243, 1998 - Differential expression of moesin in cells of hematopoietic lineage and lymphatic systems
Masumoto,J; Sagara, J; Hayama, M; Hidaka, E; Katsuyama, T; Taniguchi, S
HISTOCHEMISTRY AND CELL BIOLOGY, 110(1), 33-41, 1998 - Targeted disruption of calponin results in rapid crossbridge cycling and reduced force in phasic smooth muscle
Takahashi, K; Mitsui-Saito, M; Fuchibe, K; Yamamura, H; Taniguchi, S; Katsuki, M; Ozaki, H; Tsuchiya, T; Shibata, N; Karaki, H
BIOPHYSICAL JOURNAL, 74(2), A38-A38, 1998 - Moesin and CD44 expression in cutaneous melanocytic tumours
Ichikawa, T; Masumoto, J; Kaneko, M; Saida, T; Sagara, J; Taniguchi, S
BRITISH JOURNAL OFDERMATOLOGY, 138(5), 763-768, 1998 - Dibutyryl cAMP inhibits endotoxin-induced increases in pulmonary vascular resistance and fluid filtration coefficient in the perfused rat lung
Takeoka, M; Sakai, A; Ueda, G; Ge, RL; Ishizaki, T; Panos, RJ; Taniguchi, S
TOHOKU JOURNAL OF EXPERIMENTAL MEDICINE, 183(4), 273-284, 1997 - Suppression of pulmonary metastasis in murine B16 melanoma cells by transfection of a sialidase cDNA
Tokuyama, S; Moriya, S; Taniguchi, S; Yasui, A; Miyazaki, J; Orikasa, S; Miyagi, T
INTERNATIONAL JOURNAL OFCANCER, 73(3), 410-415, 1997 - Transformation-related expression of a low-molecular-mass tropomyosinisoform TM5/TM30nm in transformed rat fibroblastic cell lines
Miyado, K; Sato, M; Taniguchi, S
JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY, 123(6), 331-336, 1997 - A BALB/c 3T3-transformed cell line suitable for transfection assay of metastasis-inducing genes
Tatsuka, M; Ota, T; Maeda, M; Wada, M; Yamagishi, N; Taniguchi, S;Seiki, M; Odashima, S
INTERNATIONAL JOURNAL OF CANCER, 71(1), 88-93, 1997 - Influence of hypoxia and pulmonary air embolism on lung injury in perfused rat lungs
Takeoka, M; Sakai, A; Ueda, G;Ge, RL; Panos, RJ; Taniguchi, S
Respiration, 63(6), 346-351, 1996 - Decreased expression of a single tropomyosin isoform, TM5/TM30nm, results in reduction in motility of highly metastatic B16-F10 mouse melanoma cells
Miyado, K;Kimura, M; Taniguchi, S
BIOCHEMICAL AND BIOPHYSICAL RESEARCHCOMMUNICATIONS, 225(2), 427-435, 1996
