Doctor of Medicine, Shinshu University

Pathology

Glycobiology

Histochemistry & Cytochemistry

Laboratory Medicine

2023
Specially Appointed Professor, Shinshu University

2023
Emeritus Professor, Shinshu University

2021 - 2023
Vice Presidenent, Shinshu Univeristy

2020 - 2023
Distinguished Professor, Shinshu University

2019 - 2023
Dean, Shinshu Univeristy School of Medicine

2017
Member of Science Council of Japan

2011 - 2016
Vice-Dean, Shinshu Univeristy School of Medicine

2002 - 2023
Professor, Shinshu University School of Medicine

2000 - 2002
Associate Professor, Shinshu University Graduate School of Medicine

1992 - 2000
Assistant Professor, Shinshu University Hospital

1989 - 1992
Assistant, Shinshu University Hospital

1987 - 1989
Resident, Shinshu University Hospital

1993 - 1995, La Jolla Cancer Research Foundation

1983, Shinshu University, Faculty of Medicine

1987, Shinshu University, Graduate School, Division of Medicine

A spatio-temporal image analysis for growth of indeterminate pulmonary nodules detected by CT scan
Hanaoka T, Matoba H, Nakayama J, Ono S, Ikegawa K, Okada M
Radiol Phys Technol, 17, 71-82, 2024

Identification of terminal βGlcNAc on Brachyspira species in human intestinal spirochetosis
Matoba H, Iwaya M, Fujii C, Nakayama J
J Histochem Cytochem, 72, 71-78, 2024

Sirt3 regulates proliferation and progesterone production in MA-10 Leydig cells via suppression of reactive oxygen species
Matoba H, Fujii C, Maruyama K, Kawakubo M, Momose M, Sano K, Imamura H, Kurihara H, Nakayama J
Endocrinology , 165, 1-11, 2024

Impaired glycosylation of gastric mucins drives gastric tumorigenesis and serves as a novel therapeutic target.
Arai J, Hayakawa Y, Tateno H, Murakami K, Hayashi T, Hata M, Matsushita Y, Kinoshita H, Abe S, Kurokawa K, Oya Y, Tsuboi M, Ihara S, Niikura R, Suzuki N, Iwata Y, Shiokawa T, Shiomi C, Uekura C, Yamamoto K, Fujiwara H, Kawamura S, Nakagawa H, Mizuno S, Kudo T, Takahashi S, Ushiku T, Hirata Y, Fujii C, Nakayama J, Shibata S, Woods S, Worthley DL, Hatakeyama M, Wang TC, Fujishiro M
Gastroenterology , 167, 505-521, 2024

Estimation of pathological lesion stage from brain images.
Kinoshita M, Oyanagi K, Matsushima A, Kondo Y, Hirano S, Ishizawa K, Ishihara K, Terada S, Inoue T, Yazawa I, Washimi Y, Yamada M, Nakayama J, Mitsuyama Y, Ikeda SI, Sekijima Y
J Neurol Sci, 461, 123027, 2024

Dietary fat composition affects hepatic angiogenesis and lymphangiogenesis in HCV core gene transgenic mice.
Diao P, Wang Y, Jia F, Wang X, Hu X, Kimura T, Sato Y, Moriya K, Koike K, Nakayama J, Tanaka N
Liver Cancer, 12, 57-71, 2023

Development of the rabbit NASH model resembling human NASH and atherosclerosis.
Hayashi M, Kuwabara Y, Ito K, Hojo Y, Arai F, Kamijima K, Takeiri M, Wang X, Diao P, Nakayama J, Tanaka N
BIOMEDICINES, 11, 384, 2023

The usefulness of immunohistochemistry for phosphohistone H3 as a prognostic factor in myxoid liposarcoma.
Takazawa A, Yoshimura Y, Okamoto M, Tanaka A, Kito M, Aoki K, Uehara T, Takahashi J, Kato H, Nakayama J
Sci Rep, 13, 4733, 2023

Increased GS-II lectin binding and SATB2 downregulation are biological features for sessile serrated lesions and microvesicular hyperplastic polyps.
Matoba H, Iwaya M, Sato Y, Kobayashi N, Takemura H, Kouno Y, Karasawa A, Nakayama J
Pathol Int, 73, 246-254, 2023

Inflammation and subsequent nociceptor sensitization in the bone marrow are involved in an animal model of osteoarthritis pain.
Murakamia T, Ishida T, Tanaka S, Nakayama J, Tsurugizawa T, Takahashi Y, Kato F, Kawamata M
Life Sci, 324, 121736, 2023

Establishment of novel mouse model of dietary NASH rapidly progressing into liver cirrhosis and tumors.
Zheng Q, Kawaguchi M, Mikami H, Diao P, Zhang X, Zhang Z, Nakajima T, Iwadare T, Kimura T, Nakayama J, Tanaka N
CANCERS, 15, 3744, 2023

Citrullinated fibrinogen-SAAs complex causes vascular metastagenesis
Han Y, Tomita T, Kato M, Ashihara N, Higuchi Y, Matoba H, Wang W, Hayashi H, Itoh Y, Takahashi S, Kurita H, Nakayama J, Okumura N, Hiratsuka S
Nat Commun, 14, 4960, 2023

Decreased expression of TFF2 and decreased αGlcNAc glycosylation are malignant biomarkers of pyloric gland adenoma of the duodenum
Yamanoi K, Fujii C, Nakayama A, Matsuura N, Takatori Y, Kato M, Yahagi N, Nakayama J
Sci Rep, 13, 21641, 2023

Glycosylation of MUC6 by α1,4-linked N-acetylglucosamine enhances suppression of pancreatic cancer malignancy.
Yuki A, Fujii C, Yamanoi K, Matoba H, Harumiya S, Kawakubo M, Nakayama J
Cancer Sci, 113, 576-586, 2022

Acidic activated charcoal prevents obesity and insulin resistance in high-fat diet-fed mice.
Zhang X, Diao P, Yokoyama H, Inoue Y, Tanabe K, Hayashi C, Yokoyama T, Zhang Z, Hu X, Nakajima T, Kimura T, Nakayama J, Nakamuta M, Tanaka N
Front Nutr, 9, 852767, 2022

Mucin distribution in bronchiolar adenoma/ciliated muconodular papillary tumor reveals organoid differentiation simulating the normal lung.
Matoba H, Ikeyama M, Kobayashi N, Takemura H, Hanaoka T, Sato Y, Nakayama J
Pathol Int, 72, 300-306, 2022

MUC6 expression is a preferable prognostic marker for invasive mucinous adenocarcinoma of the lung.
Yamanoi K,　Fujii C, Yuzuriha H, Kumazawa M, Shimoda M, Emoto K, Asamura H, Nakayama J
Histochem Cell Biol, 157, 671-684, 2022

Extramedullary hematopoiesis in gastric wall under early gastric cancer in a man with a myeloproliferative disorder: a case report.
Kimura D, Nakayama J, Hanaoka T, Muraki T, Takeoka Y, Nakamura R, Nakamura A, Takahata S, Ishizaka N, Motoyama H
J Surg Case Rep, 7, 1-4, 2022

TAK1 limits death receptor Fas-induced proinflammatory cell death in macrophages.
Maeda K, Nakayama J, Taki S, Sanjo H
J Immunol, 209, 1173-1179, 2022

α1,4-linked N-acetylglucosamine suppresses gastric cancer development by inhibiting MUC1-mediated signaling.
Fujii C, Harumiya S, Sato Y, Kawakubo M, Matoba H, Nakayama J
Cancer Sci, 113, 3852-3863, 2022

Effects of orally administered Euglena gracilis and its reserve polysaccharide, paramylon, on gastric dysplasia in A4gnt knockout mice.
Iida M, Desamero MJ, Yasuda K, Nakashima A, Suzuki K, Chambers JK, Uchida K, Ogawa R, Hachimura S, Nakayama J, Kyuwa S, Miura K, Kakuta S, Hirayama K
Sci Rep, 11, 13640, 2021

Decreased gastric gland mucin-specific O-glycans are involved in the progression of ovarian primary mucinous tumours.
Ohya A, Matoba H, Fujinaga Y, Nakayama J
Acta Histochem Cytochem, 54, 115-122, 2021

Systematic investigation of the skin in Chst14-/- mice: a model for skin fragility in musculocontractural Ehlers-Danlos syndrome caused by CHST14 variants (mcEDS-CHST14).
Hirose T, Mizumoto S, Hashimoto A, Takahashi Y, Yoshizawa T, Nitahara-Kasahara Y, Takahashi N, Nakayama J, Takehana K, Okada T, Nomura Y, Yamada S, Kosho T, Watanabe T
GLYCOBIOLOGY, 31, 137-150, 2021

Cholestenone functions as an antibiotic against Helicobacter pylori by inhibiting biosynthesis of the cell wall component CGL.
Kobayashi J, Kawakubo M, Fujii C, Arisaka N, Miyashita M, Sato Y, Komura H, Matoba H, Nakayama J
Proc Natl Acad Sci USA, 118, e2016469118, 2021

A trans-fatty acid-rich diet promotes liver tumorigenesis in HCV core gene transgenic mice.
Hu X, Wang X, Jia F, Tanaka N, Kimura T, Nakajima T, Sato Y, Moriya K, Koike K, Gonzalez FJ, Nakayama J, Aoyama T
CARCINOGENESIS, 41, 159-170, 2020

Cecal tumorigenesis in aryl hydrocarbon receptor-deficient mice depends on cecum-specific mitogen-activated protein kinase pathway activation and inflammation.
Matoba H, Takamoto M, Fujii C, Kawakubo M, Kasuga E, Matsumura T, Natori T, Misawa K, Taniguchi S, Nakayama J
Am J Pathol, 190, 453-468, 2020

Dietary restriction suppresses steatosis-associated hepatic tumorigenesis in HCV core gene transgenic mice.
Jia F, Diao P, Wang X, Hu X, Kimura T, Nakamuta M, Nakamura I, Shirotori S, Sato Y, Nakayama J, Moriya K, Koike K, Gonzalez FJ, Aoyama T, Naoki Tanaka N
Liver Cancer, 9, 529-548, 2020

Polyunsaturated fatty acid deficiency affects sulfatides and other sulfated glycans in lysosomes through autophagy-mediated degradation.
Wang Y, Nakajima T, Diao P, Yamada Y, Nakamura K, Nakayama J, Tanaka N, Aoyama T, Kamijo Y
FASEB J, 34, 9594-9614, 2020

Diffuse MIST1 expression and decreased α1,4-linked N-acetylgludosamine (αGlcNAc) glycosylation on MUC6 are distinct hallmarks for gastric neoplasms showing oxyntic gland differentiation.
Yamada S, Yamanoi K, Sato Y, Nakayama J
HISTOPATHOLOGY, 77, 413-422, 2020

A saturated fatty acid-rich diet enhances hepatic lipogenesis and tumorigenesis in HCV core gene transgenic mice.
Diao P, Wang X, Jia F, Kimura T, Hu X, Shirotori S, Nakamura I, Sato Y, Nakayama J, Moriya K, Koike K, Gonzalez FJ, Aoyama T, Tanaka N
J Nutr Biochem, 85, 108460, 2020

Overcoming the blood-brain-barrier by Annexin A1-binding peptide to target brain tumors.
Nonaka M, Suzuki-Anekoji M, Nakayama J, Mabashi-Asazuma H, Jarvis DL, Yeh J, Yamasaki K, Akama TO, Huang C, Campos AR, Nagaoka M, Sasai T, Kimura-Takagi I, Suwa Y, Yaegashi T, Shibata TK, Sugihara K, Nishizawa-Harada C, Fukuda M, Fukuda MN
Brit J Cancer, 123, 1633-1643, 2020

Decreased alpha-1,4-linked N-acetylglucosamine glycosylation in biliary tract cancer progression from biliary intraepithelial neoplasia to invasive adenocarcinoma.
Okumura M, Yamanoi K, Uehara T, Nakayama J
Cancer Sci, 111, 4629-4635, 2020

Annexin A1 expression is correlated with malignant potential of renal cell carcinoma.
Yamanoi M, Fujii C, Yamanoi K, Fukuda MN, Nakayama J
Int J Urol, 26, 284-290, 2019

Structural alteration of glycosaminoglycan side chains and spatial disorganization of collagen networks in the skin of patients with mcEDS-CHST14.
Hirose T, Takahashi N, Tangkawattana P, Minaguchi J, Mizumoto S, Yamada S, Miyake N, Hayashi S, Hatamochi A, Nakayama J, Yamaguchi T, Hashimoto A, Nomura Y, Takehana K, Kosho T, Watanabe T
Biochim Biophys Acta Gen Subj, 1863, 623-631, 2019

A high-cholesterol diet promotes steatohepatitis and liver tumorigenesis in HCV core gene transgenic mice.
Wang X, Tanaka N, Hu X, Kimura T, Lu Y, Jia F, Sato Y, Nakayama J, Moriya K, Koike, K, Aoyama T
Arch Toxicol, 93, 1713-1725, 2019

Analysis of A4gnt knockout mice reveals an essential role for gastric sulfomucins in preventing gastritis cystica profunda.
Kawakubo M, Komura H, Goso Y, Okumura M, Sato Y, Fujii C, Miyashita M, Arisaka N, Harumiya S, Yamanoi K, Yamada S, Kakuta S, Kawashima H, Fukuda MN, Fukuda M, Nakayama J
J Histochem Cytochem, 67, 759-770, 2019

TAK1 safeguards macrophages against proinflammatory cell death.
Sanjo H, Nakayama J, Yoshizawa T, Fehling HJ, Akira S, Taki S
J Immunol, 203, 783-788, 2019

αGlcNAc and its catalyst α4GnT are diagnostic and prognostic markers in uterine cervical tumor, gastric type.
Ida K, Yamanoi K, Asaka S, Takeuchi H, Miyamoto T, Shiozawa T, Nakayama J
Sci Rep, 9, 13043, 2019

Tumor-suppressing potential of stingless bee propolis in in vitro and in vivo models of differentiated-type gastric adenocarcinoma.
Desamero MJ, Kakuta S, Tang Y, Chambers JK, Uchida K, Estacio MA, Cervancia C, Kominami Y, Ushio H, Nakayama J, Nakayama H, Kyuwa S
Sci Rep, 9, 19635, 2019

Cholesterol-α-glucosyltransferase gene is present in most Helicobacter species including gastric non-Helicobacter pylori helicobacters obtained from Japanese patients.
Kawakubo M, Horiuchi K, Matsumoto T, Nakayama J, Akamatsu T, Katsuyama T, Ota H, Sagara J
HELICOBACTER, 23, e12449, 2018

Vascular abnormalities in the placenta of Chst14-/- fetuses: implications in the pathophysiology of perinatal lethality of the murine model and vascular lesions in human CHST14/D4ST1 deficiency.
Yoshizawa T, Mizumoto S, Takahashi Y, Shimada S, Sugahara K, Nakayama J, Takeda S, Nomura Y, Nitahara-Kasahara Y, Okada T, Matsumoto K, Yamada S, Kosho T
GLYCOBIOLOGY, 28, 80-89, 2018

Osteosarcoma arising in fibrous dysplasia, confirmed by mutational analysis of GNAS gene.
Sugiura Y, Kanda H, Motoi N, Nomura K, Inamura K, Okada E, Matsumoto H, Shimoji T, Matsumoto S, Nakayama J, Takazawa Y, Ishikawa Y, Machinami R
Pathol Res Pract, 214, 318-324, 2018

Pulmonary adenocarcinoma possibly developed from the cut-end of small-sized adenocarcinoma in the lung periphery as recurrence 13 years after its wedge resection.
Hanaoka T, Kurai M, Okada M, Ishizone S, Karasawa F, Iizuka A, Ikeyama M, Nakayama J
Surg Case Rep, 4, 2, 2018

Increased expression of Y-box-binding protein-1 in hind-limb muscles during regeneration from ischemic injury in mice.
Fuke M, Narita M, Wada Y, Seto T, Okada K, Nakayama J, Izumi H, Ito K-i
Tohoku J Exp Med, 244, 53-62, 2018

Orally administrated brown seaweed-derived β-glucan effectively restrained development of gastric dysplasia in A4gnt KO mice that spontenously develop gastric adenocarcinoma.
Desamero MJ, Kakuta S, Chambers JK, Uchida K, Hachimura S, Takamoto M, Nakayama J, Nakayama H, Kyuwa S
Int Immunopharmacol, 60, 211-220, 2018

Upregulated expression of La ribonucleoprotein domain family member 6 and collagen type I gene following water-filtered broad-spectrum near-infrared irradiation in a 3-dimensional human epidermal tissue culture model as revealed by microarray analysis.
Tanaka Y, Nakayama J
Australas J Dermatol, 59, e87-e92, 2018

Reduced αGlcNAc glycosylation on gastric gland mucin is a biomarker of malignant potential for gastric cancer, Barrett’s adenocarcinoma, and pancreatic cancer.
Yamanoi K, Nakayama J
Histochem Cell Biol, 149, 569-575, 2018

Gastric gland mucin-specific O-glycan expression decreases as tumor cells progress from lobular endocervical gland hyperplasia to cervical mucinous carcinoma, gastric type.
Yamanoi K, Ishii K, Tsukamoto M, Asaka S, Nakayama J
Virchows Arch, 473, 305-311, 2018

Spinal manifestations in 12 patients with musculocontractural Ehlers-Danlos syndrome caused by CHST14/D4ST1 deficiency (mcEDS-CHST14).
Uehara M, Kosho T, Yamamoto N, Takahashi HE, Shimakura T, Nakayama J, Kato H, Takahashi J
Am J Med Genet, 176A, 2331-2341, 2018

Potential involvement of chondroitin sulfate A in the pathogenesis of ameloblastoma.
Li X, Kurita H, Xiao T, Iijima K, Kurashina K, Nakayama J
Acta Histochem, 119, 439-445, 2017

Adenocarcinoma of Barrett’s esophagus in a dog.
Chambers JK, Saito T, Fukushima K, Kakuta S, Nakayama J, Ohno K, Tsujimoto H, Nakayama H, Uchida K
J Toxicol Pathol, 30, 239-243, 2017

Gastric hepatoid adenocarcinoma resulting in a spontaneous gastric perforation: a case report and review of the literature.
Yoshizawa J, Ishizone S, Ikeyama M, Nakayama J
BMC CANCER, 17, 368, 2017

Gastric gland mucin-specific O-glycan expression decreases with tumor progression from precursor lesions to pancreatic cancer.
Ohya A, Yamanoi K, Shimojo H, Fujii C, Nakayama J
Cancer Sci, 108, 1897-1902, 2017

Cloning of Helicobacter suis cholesterol α-glucosyltransferase and production of an antibody capable of detecting it in formalin-fixed, paraffin-embedded gastric tissue sections.
Kawakubo M, Horiuchi K, Komura H, Sato Y, Kato M, Ikeyama M, Fukushima M, Yamada S, Ishizone S, Matsumoto T, Ota H, Sagara J, Nakayama J
Histochem Cell Biol, 148, 463-471, 2017

Interleukin-17A-deficient mice are highly susceptible to Toxoplasma gondii infection due to excessively induced T. gondii HSP70 and interferon gamma poduction.
Moroda M, Takamoto M, Iwakura Y, Nakayama J, Aosai F
Infect Immun, 85, e00399-17, 2017

Reversion-Inducing cysteine-rich protein with Kazal motifs (RECK) in angiogenesis of microvessels in glioblastoma.
Kanaya K, Sakai K, Hongo K, Fukushima M, Kawakubo M, Nakayama J
J Clin Mol Pathol, 1, No.2:12, 2017

High expression of ADAM10 predicts a poor prognosis for patients with glioblastoma
Kanaya K, Sakai K, Hongo K, Fukushima M, Kawakubo M, Nakayama J
Int J Clin Exp Pathol, 10(1), 618-624, 2017

Unexpected Occurrence of Fetal Hemophagocytic Syndrome in a Patient with Hereditary Diffuse Leukoencephalopathy with Spheroids
Kondo Y, Kinoshita M, Yoshida T, Matoba H, Uehara T, Ikeyama M, Nakayama J, Yoshida K, Ikeda S-i
Case Rep Clin Med, 5, 77-84, 2016

The ROS-generating oxidase Nox1 is required for epithelial restitution following colitis
Kato M, Marumo M, Nakayama J, Matsumoto M, Yabe-Nishimura C, Kamata T
Exp Anim, 65, 197-205, 2016

Up-regulated epidermal growth factor receptor expression following near-infrared irradiation simulating solar radiation in a 3-dimensional reconstructed human corneal epithelial tissue culture model
Tanaka Y, Nakayama J
Clin Interv Aging, 11, 1027-1033, 2016

Axonal TDP-43 aggregates in sporadic amyotrophic lateral sclerosis.
Onozato T, Nakahara A, Suzuki-Kouyama E, Hineno A, Yasude T, Nakamura T, Yahikozawa H, Watanabe M, Kayanuma K, Makishita H, Ohara S, Hashimoto T, Higuchi K, Sakai T, Asano K, Hashimoto T, Kanno H, Nakayama J, Oyanagi K
Neuropathol Appl Neurobiol, 42(6), 561-572, 2016

Chondroitin sulfate synthase 1 expression is associated with malignant potential of soft tissue sarcomas with myxoid substance
Momose T, Yoshimura Y, Harumiya S, Isobe K, Kito M, Fukushima M, Kato H, Nakayama J
Hum Pathol, 50, 15-23, 2016

Enhanced Expression of Fibroblast Growth Factor Receptor 3 IIIc Promotes Human Esophageal Carcinoma Cell Proliferation
Ueno N, Shimizu A, Kanai M, Iwaya Y, Nakayama J, Seo MK
J Histochem Cytochem, 64(1), 7-17, 2016

Nox4-generated ROS Regulate TGF-β1-induced Motility of Colon Cancer Cells through the Low Molecular Weight Protein Tyrosine Phosphatase-Rho Signaling Pathway
Zhang Y, Nakayama J, Kamata T
Shinshu Medical Journal, 63(5), 281-293, 10 Oct. 2015

Breast metastases of gastric signet-ring cell carcinoma: a report of two cases and review of the literature
Iesato A, Oba T, Ono M, Hanamura T, Watanabe T, Ito T, Kanai T, Maeno K, Ishizaka K, Kitabatake H, Takeuchi D, Suzuki A, Nakayama J, Ito K
OncoTargets Ther, 8, 91-97, 2015

Reduced gland mucin-specific O-glycan in gastric atrophy: A possible risk factor for differentiated-type adenocarcinoma of the stomach
Yamada S, Okamura T, Kobayashi S, Tanaka E, Nakayama J
J Gastroenterol Hepatol, 30(10), 1478-1484, 2015

Malignant meningioma with adenocarcinoma-like metaplasia: Demonstration of intestinal phenotype
Takayama Y, Nobusawa S, Ochiai I, Watanabe H, Ishigame H, Ikota H, Hirato J, Nakayama J, Yokoo H
Neuropathology, 35(2), 158-164, 2015

Decreased expression of gastric gland mucin-specific glycan α1,4-linked N-acetylglucosamine on its scaffold mucin 6 is associated with malignant potential of pyloric gland adenoma of the stomach
Yamanoi K, Sekine S, Higuchi K, Kushima R, Nakayama J
HISTOPATHOLOGY, 67(6), 898-904, 2015

Overexpression of O-GlcNAc by prostate cancer cells is significantly associated with poor prognosis of patients
Kamigaito T, Okaneya T, Shimojo H, Nishizawa O, Nakayama J
Prostate Cancer Prost Dis, 17, 18-22, 2014

Defect of suppression of inflammasome-independent interleukin-8 secretion from SW982 synovial sarcoma cells by familial Mediterranean fever-derived pyrin mutations
Sugiyama R, Agematsu K, Migita K, Nakayama J, Mokuda S, Ogura F, Haraikawa K, Okumura C, Suehiro S, Morikawa S, Ito Y, Masumoto J
Mol Biol Rep, 41, 545-553, 2014

Reduced expression of αGlcNAc in Barrett’s esophagus adjacent to Barrett’s adenocarcinoma - Possible biomarker to predict the malignant potential of Barrett’s esophagus –
Iwaya Y, Hasebe O, Koide N, Kitahara K, Suga T, Shinji A, Muraki T, Yokosawa S, Yamada S, Arakura N, Tanaka E, Nakayama J
HISTOPATHOLOGY, 64, 536-546, 2014

Loss of gastric gland mucin-specific O-glycan is significantly associated with progression of differentiated-type adenocarcinoma of the stomach
Shiratsu K, Higuchi K, Nakayama J
Cancer Sci, 105, 126-133, 2014

Development of pro-apoptotic peptides as potential therapy for peritoneal endometriosis
Sugihara K, Kobayashi Y, Suzuki A, Tamura N, Motamedchaboki K, Huang C-T, Akama T, Pecotte J, Frost P, Bauer C, Jimenez J, Nakayama J, Aoki D, Fukuda MN
Nat Commun, 5, 4478, 2014

Gliomatosis encephali” as a novel category of brain tumors by the first autopsy case report of gliomatosis cerebelli
Nakahara A, Yoshida T, Yazawa M, Ehara T, Nakayama J, Kakita A, Ogura R, Asakawa M, Suzuki-Kouyama E, Oyanagi K
Neuropathology, 34(3), 295-303, 2014

Synthetic di-sulfated iduronic acid attenuates asthmatic response by blocking T-cell recruitment to inflammatory sites
Nonaka M, Bao X, Matsumura F, Götze S, Kandasamy J, Kononov A, Broide DH, Nakayama J, Seeberger PH, Fukuda M
Proc Natl Acad Sci USA, 111(22), 8173-8178, 2014

Dual roles of gastric gland mucin-specific O-glycans in prevention of gastric cancer
Nakayama J
Acta Histochem Cytochem, 47(1), 1-9, 2014

Crucial role of hyaluronan in neointimal formation after vascular injury
Kashima Y, Takahashi M, Shiba Y, Itano N, Izawa A, Koyama J, Nakayama J, Taniguchi S, Kimata K, Ikeda U
PLOS ONE, 8(3), e58760, 2013

High levels of FOXP3+ regulatory T cells in gastric MALT lymphoma predicts responsiveness to Helicobacter pylori eradication
Iwaya Y, Kobayashi M, Momose M, Hiraoka N, Sakai Y, Akamatsu T, Tanaka E, Ohtani H, Fukuda M, Nakayama J
HELICOBACTER, 18(5), 356-362, 2013

Periductal induction of high endothelial venule-like vessels in type 1 autoimmune pancreatitis
Maruyama M, Kobayashi M, Sakai Y, Hiraoka N, Oya A, Kageyama S, Tanaka E, Nakayama J, Morohoshi T
Pancreas, 42(1), 53-59, 2013

Lymphocyte recruitment via high endothelial venules in lymphoid stroma of Warthin's tumour
Ohya A, Kobayashi M, Sakai Y, Kawashima H, Kageyama S, Nakayama J
PATHOLOGY, 45(2), 150-154, 2013

Immunohistochemical expression of core2 β1-6 N-acetylglucosaminyl transferase 1 (C2GnT1) in endometrioid type of endometrial carcinoma: a novel potential prognostic factor
Miyamoto T, Suzuki A, Asaka R, Ishikawa, Yamada Y, Kobara H, Nakayama J, Shiozawa T
HISTOPATHOLOGY, 62(7), 986-993, 2013

In vivo regulation of steroid hormones by the chst10 sulfotransferase in mouse
Suzuki-Anekoji M, Suzuki A, Wu S-W, Angata K, Murai K, Sugihara K, Akama TO, Khoo K-H, Nakayama J, Fukuda MN, Fukuda M
J Biol Chem, 288, 5007-5016, 2013

Helicobacter pylori cholesteryl α-glucosides contribute to its pathogenicity and immune response by natural killer T cells
Ito Y, Vela JL, Matsumura F, Hoshino H, Tyznik A, Lee H, Girardi E, Zajonc DM, Liddington, Kobayashi M, Bao X, Bugaytsova J, Borén T, Jin R, Zong Y, Seeberger PH, Nakayama J, Kronenberg M, Fukuda M
PLOS ONE, 8(12), e78191, 2013

Primary malignant sarcomatoid mesothelioma in the pericardium
Tateishi K, Ikeda M, Yokoyama T, Urushihata K, Yamamoto H, Hanaoka M, Kubo K, Sakai Y, Nakayama J, Koizumi T
Intern Med, 52(2), 249-253, 2013

Role of GalNAc4S-6ST in astrocytic tumor progression
Kobayashi T, Yan H, Kurahashi Y, Ito Y, Maeda H, Tada T, Hongo K, Nakayama J
PLOS ONE, 8, e54278, 2013

Two distinct lymphocyte homing systems involved in the pathogenesis of chronic inflammatory gastrointestinal diseases
Kobayashi M, Hoshino H, Suzawa K, Sakai Y, Nakayama J, Fukuda M
Semin Immunopathol, 34, 401-413, 2012

Non-thermal DNA damage of cancer cells using near-infrared irradiation
Tanaka Y, Tatewaki N, Nishida H, Eitsuka T, Ikekawa N, Nakayama J
Cancer Sci, 103(8), 1467-1473, 2012

Essential role of gastric gland mucin in preventing gastric cancer in mice
Karasawa F, Shiota A, Goso Y, Kobayashi M, Sato Y, Masumoto J, Fujiwara M, Yokosawa S, Muraki T, Miyagawa S, Ueda M, Fukuda MN, Fukuda M, Ishihara K, Nakayama J
J Clin Invest, 122(3), 923-934, 2012

Expression of long-form N-acetylglucosamine-6-O-sulfotransferase 1 in human high endothelial venules
Fujiwara M, Kobayashi M, Hoshino H, Uchimura K, Nakada T, Masumoto J, Sakai Y, Fukuda M, Nakayama J
J Histochem Cytochem, 60(5), 397-407, 2012

O-Glycans carrying non-sulfated sialyl Lewis X appearing on HEV-like vessels in gastric MALT lymphoma function as L-selectin ligands
Kobayashi M, MitomaJ, Hoshino H, Yu SY, Shimojo Y, Suzawa K, Khoo KH, Fukuda M, Nakayama J
J Pathol, 224, 67-77, 2011

COP35, a cholangiocarcinoma-binding oligo-peptide, interacts with the clathrin heavy chain accompanied by GRP78
Kitahara H, Masumoto J, Parker AL, Maruta F, Kubo N, Shimizu A, Akita N, Miwa S, Kobayashi N, Nakayama J, Miyagawa S
Mol Cancer Res, 9(6), 688-701, 2011

A Rare Lung Nodule Consisting of Adenocarcinoma and Amyloid Deposition in a Patient with Primary Systemic AL Amyloidosis
Miyazaki D, Yazaki M, Ishii W, Matsuda M, Hoshii Y, Nara K, Nakayama J, Ikeda S
Inter Med, 50, 243-246, 2011

Membrane-associated activation of cholesterol α-glucosyltransferase, an enzyme responsible for biosynthesis of cholesteryl-α-D-glucopyranoside in Helicobacter pylori critical for its survival
Hoshino H, Tsuchida A, Kametani K, Mori M, Nishizawa T, Suzuki T, Nakamura H, Lee H, Ito Y, Kobayashi M, Masumoto J, Fujita M, Fukuda M, Nakayama J
J Histochem Cytochem, 59(1), 98-105, 2011

Reduced glycosylation of α-dystroglycans on carcinoma cells contributes to formation of highly infiltrative histological patterns in prostate cancer
Shimojo H, Kobayashi M, Kamigaito T, Shimojo Y, Fukuda M, Nakayama J
Prostate, 71, 1151-1157, 2011

Targeted drug delivery to tumor vasculature by a carbohydrate mimetic peptide
Hatakeyama S, Sugihara K, Shibata TK, Nakayama J, Akama TO, Tamura N, Wong S, Bobkov AA, Takano Y, Ohyama C, Fukuda M, Fukuda MN
Proc Natl Acad Sci USA, 108(49), 19587–19592, 2011

HNK-1 glycan functions as a tumor suppressor for astrocytic tumor
Suzuki M, Suzuki M, Kobayashi T, Sato Y, Nakayama J, Suzuki A, Bao X, Angata K, Fukuda M
J Biol Chem, 286(37), 32824-32833, 2011

Glycoside hydrolase family 89 α-N-acetylglucosaminidase from Clostridium perfringens specifically acts on GlcNAcα 1,4Galβ1R at the non-reducing terminus of O-glycans in gastric mucin
Fujita M, Tsuchida A, Hirata A, Kobayashi N, Goto K, Osumi K, Hirose Y, Nakayama J, Yamanoi T, Ashida H, Mizuno K
J Biol Chem, 286(8), 6479-6489, 2011

Inflammasome activation of cardiac fibroblasts is effential for myocardial ischemia/reperfusion injury
Kawaguchi M, Takahashi M, Hata T, Kashima Y, Usui F, Morimoto H, Izawa A, Takahashi Y, Masumoto J, Koyama J, Hongo M, Noda T, Nakayama J, Sagara J, Taniguchi S, Ikeda U
Circulation, 123, 594-604, 2011

Gliosarcoma arising from a fibrillary astrocytoma
Kobayashi T, Sakai K, Tada T, Sekiguchi Y, Hara Y, Kodama K, Goto T, Tanaka Y, Sano K, Nakayama J, Hongo K
J Clin Neurosci, 18(9), 1251-1254, 2011

An integrin α4β7•IgG heterodimeric chimera binds to MAdCAM-1 on high endothelial venules in gut-associated lymphoid tissue
Hoshino H, Kobayashi M, Mitoma J, Sato Y, Fukuda M, Nakayama J
J Histochem Cytochem, 59, 572-583, 2011

Core2 O-glycan structure functions in gastrointestinal cell differentiation by regulating cell surface expression of sucrase isomaltase and dipeptidyl peptidase-IV
Lee SH, Yu SY, Nakayama J, Khoo KH, Stone EL, Fukuda M, Marth JD, Fukuda M
J Biol Chem, 285(48), 37683-37692, 2010

Nasu-Hakola disease: The first case reported by Nasu and review
Kaneko M, Sano K, Nakayama J, Amano N
Neuropathology, 30(5), 463-470, 2010

Reversion-inducing cysteine-rich protein with kazal motifs and matrix metalloproteinase-9 are prognostic markers in skull base chordomas
Rahmah, Nunung Nur; Sakai, Keiichi; Nakayama, Jun; Hongo, Kazuhiro
NEUROSURGICAL REVIEW, 33(2), 167-173, 2010

Selective alpha(1A)-Adrenoceptor Stimulation Induces Mueller's Smooth Muscle Contraction in an Isolated Canine Upper Eyelid Preparation
Yano, Shiharu; Hirose, Masamichi; Nakada, Tsutomu; Nakayama, Jun; Matsuo, Kiyoshi; Yamada, Mitsuhiko
CURRENT EYE RESEARCH, 35(5), 363-369, 2010

Non-thermal cytocidal effect of infrared irradiation on cultured cancer cells using specialized device
Tanaka, Yohei; Matsuo, Kiyoshi;Yuzuriha, Shunsuke; Yan, Huimin; Nakayama, Jun
Cancer Sci, 101(6), 1396-1402, 2010

Therapeutic and preventive effects of methotrexate on zymosan-induced arthritis in SKG mice
Nagate T, Kawai J, Nakayama J
J Vet Med Sci, 71, 713-717, 2009

Tumor suppressor function of laminin-binding alpha-dystroglycan requires a distinct beta3-N-acetylglucosaminyltransferase
Bao X, Kobayashi M, Hatakeyama S, Angata K, Gullberg D, Nakayama J, Fukuda MN, Fukuda M
Proc Natl Acad Sci USA, 106, 12109-12114, 2009

Identification of mRNA splicing factor as the endothelial receptor for carbohydrate-dependent lung colonization of cancer cells
Hatakeyama S, Sugihara K, Nakayama J, Akama TO, Wong SA, Kawashima H, Zhang J, Smith DF, Ohyama C, Fukuda M, Fukuda MN
Proc Natl Acad Sci USA, 106(9), 3095-3100, 2009

Antigen p57/Kip2 as a potential negative regulator of human astrocytoma growth
Akaishi, Kotaro; Nakayama, Jun; Sakai, Keiichi; Kobayashi, Tatsuya; Rutka, James T.
JOURNAL OF CLINICAL NEUROSCIENCE, 16(12), 1615-1618, 2009

Role of sulfated O-glycans expressed by high endothelial venule-like vessels in pathogenesis of chronic inflammatory gastrointestinaldiseases
Kobayashi, Motohiro; Fukuda, Minoru; Nakayama, Jun
BIOLOGICAL & PHARMACEUTICAL BULLETIN, 32(5), 774-779, 2009

Trophinin: what embryo implantation teaches us about human cancer
Fukuda MN, Sugihara K, Nakayama J
Cancer Biol Ther, 7, 1165-1170, 2008

Prognositic significance of the immunohistochemical staining of cleaved-caspase-3, an activated-form of caspase-3, in gliomas
Kobayashi T, Masumoto J, Tada T, Nomiyama T, Hongo K, Nakayama J
Clin Cancer Res, 13(13), 3868-3874, 2007

RNA interference-mediated knock-down of transient receptor potential vanilloid 1 prevents forepaw inflammatory hyperalgesia in rat
Kasama S, Kawakubo M, Suzuki T, Nishizawa T, Ishida A, Nakayama J
Eur J Neurosci, 25, 2956-2963, 2007

The utility of formalin-fixed and paraffin-embedded tissue blocks for quantitative analysis of N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase mRNA expressed by colorectal cancer cells
Ito Y, Watanabe M, Nishizawa T, Omachi T, Kobayashi T, Habuchi O, Nakayama J:
Acta Histochem Cytochem, 40(2), 53-59, 2007

Preferential induction of peripheral lymph node addressin on high endothelial venule-like vessels in the active phase of ulcerative colitis
Suzawa K, Kobayashi M, Sakai Y, Hoshino H, Watanabe M, Harada O, Ohtani H, Fukuda M, Nakayama J
Am J Gastroenterol, 102, 1499-1509, 2007

The role of trophinin, an adhesion molecule unique to human trophoblasts, in progression of colorectal cancer
Harada O, Suga T, Suzuki T, Nakamoto K, Kobayashi M, Nomiyama T, Nadano D, Ohyama C, Fukuda MN, Nakayama J
Int J Cancer, 121(5), 1072-1078, 2007

Immunohistochemical demonstration of proliferating lymphatic vessels in colorectal carcinoma and its clinicopathological significance
Omachi T, Kawai Y, Mizuno R, Nomiyama T, Miyagawa S, Ohhashi T, Nakayama J
Cancer Lett, 246(42737), 167-172, 2007

Comparison of the histological and immunohistochemical features of the thymus in young- and elderly-onset myasthenia gravis without thymoma
Ishii, W; Matsuda, M; Hanyuda, M; Momose, M; Nakayama, J; Ehara, T; Ikeda, S
J Clin Neurosci, 14(2), 110-115, 2007

Expression profiling of glycosyltransferases and related enzymes using in situ hybridization
Nakayama J, Suzuki M, Suzuki M, Fukuda M
Methods Enzymol, 416, 120-129, 2006

Efficacy of mycophenolic acid combined with KRP-203, a novel immunomodulator, in a rat heart transplantation model
Suzuki, C; Takahashi, M; Morimoto, H; Izawa, A; Ise, H; Fujishiro, J; Murakami, T; Ishiyama, J; Nakada, A; Nakayama, J; Shimada, K; Ikeda, U; Kobayashi, E
J Heart Lung Transpl, 25(3), 302-309, 2006

Inhibition of NADPH oxidase 4 activates apoptosis via the AKT/apoptosis signal-regulating kinase 1 pathway in pancreatic cancer PANC-1 cells
Mochizuki, T; Furuta, S; Mitsushita, J; Shang, W; Ito, M; Yokoo, Y; Yamaura, M; Ishizone, S; Nakayama, J; Konagai, A; Hirose, K; Kiyosawa,K; Kamata, T
Oncogene, 25(26), 3699-3707, 2006

Efficacy of S-1 for patients with peritoneal metastasis of gastric cancer
Ishizone, S; Maruta, F; Saito, H; Koide, N; Sugiyama, A; Nakayama, J; Miyagawa, S
Chemotherapy, 52(6), 301-307, 2006

Terminal alpha 1,4-linked N-acetylglucosamine in Helicobacter pylori-associated intestinal metaplasia of the human stomach and gastric carcinoma cell lines
Ferreira, B; Marcos, NT; David, L; Nakayama, J; Reis, CA
J Histochem Cytochem, 54(5), 585-591, 2006

Female adnexal tumor of probable wolffian origin: Morphological, immunohistochemical, and ultrastructural study with c-kit gene analysis
Harada, O; Ota, H; Takagi, K; Matsuura, H; Hidaka, E; Nakayama, J
Pathol Int, 56(2), 95-100, 2006

Hypermethylation of ASC/TMS1 is a sputum marker for late-stage lung cancer
Machida, EO; Brock, MV; Hooker, CM; Nakayama, J; Ishida, A; Amano, J; Picchi, MA; Belinsky, SA; Herman, JG; Taniguchi, S; Baylin, SB
Cancer Res, 66(12), 6210-6218, 2006

Clinical utility of quantitative RT-PCR targeted to alpha 1,4-N-acetylglucosaminyltransferase mRNA for detection of pancreatic cancer
Ishizone, S; Yamauchi, K; Kawa, S; Suzuki, T; Shimizu, F; Harada, O; Sugiyama, A; Miyagawa, S; Fukuda, M; Nakayama, J
Cancer Sci, 97(2), 119-126, 2006

Identification of oligopeptides binding to peritoneal tumors of gastric cancer
Akita, N; Maruta, F; Seymour, LW; Kerr, DJ; Parker, AL; Asai, T; Oku, N; Nakayama, J; Miyagawa, S
Cancer Sci, 97(10), 1075-1081, 2006

Rotigaptide (ZP123) improves atrial conduction slowing in chronic volume overload-induced dilated atria
Haugan, K; Miyamoto, T; Takeishi, Y; Kubota, I; Nakayama, J; Shimojo, H; Hirose, M
Basic Clin Pharmacol Toxicol, 99(1), 71-79, 2006

Essential and mutually compensatory roles of alpha-mannosidase II and alpha-mannosidase IIx in N-glycan processing in vivo in mice
Akama, TO; Nakagawa, H; Wong, NK; Sutton-Smith, M; Dell, A; Morris, HR; Nakayama, J; Nishimura, SI; Pai, A; Moremen, KW; Marth, JD; Fukuda, MN
Proc Natl Acad Sci USA, 103(24), 8983-8988, 2006

Matrix morphogenesis in cornea is mediated by the modification of keratan sulfate by GlcNAc 6-O-sulfotransferase
Hayashida, Y; Akama, TO; Beecher, N; Lewis, P; Young, RD;Meek, KM; Kerr, B; Hughes, CE; Caterson, B; Tanigami, A; Nakayama, J; Fukada, MN; Tano, Y; Nishida, K; Quantock, AJ
Proc Natl Acad Sci USA, 103(36), 13333-13338, 2006

Lanosterol synthase mutations cause cholesterol deficiency-associated cataracts in the Shumiya cataract rat
Mori, M; Li, GX; Abe, I; Nakayama, J; Guo, ZJ; Sawashita, J; Ugawa, T; Nishizono, S; Serikawa, T; Higuchi, K; Shumiya, S
J Clin Invest, 116(2), 395-404, 2006

Expression cloning of cholesterol alpha-glucosyltransferase, a unique enzyme that can be inhibited by natural antibiotic gastric mucin O-glycans, from Helicobacter pylori
Lee, H; Kobayashi, M; Wang, P; Nakayama, J; Seeberger, PH; Fukuda, M
Biochem Biophys Res Commun, 349(4), 1235-1241, 2006

N-acetylglucosamine-6-O-sulfotransferases 1 and 2 cooperatively control lymphocyte homing through L-selectin ligand biosynthesis in high endothelial venules
Kawashima H, Petryniak B, Hiraoka N, Mitoma J, Huckaby V, Nakayama J, Uchimura K, Kadomatsu K, Muramatsu T, Lowe JB, Fukuda M
Nat Immunol, 6(11), 1096-1104, 2005

Polysialic acid facilitates tumor invasion by glioma cells
Suzuki M, Suzuki M, Nakayama J, Suzuki A, Angata K, Chen S, Sakai K, Hagihara K, Yamaguchi Y, Fukuda M
GLYCOBIOLOGY, 15(9), 887-894, 2005

Expression of core 2 beta 1,6-N-acetylglucosaminyltransferase facilitates prostate cancer progression
Hagisawa S, Ohyama C, Takahashi T, Endoh M, Moriya T, Nakayama J, Arai Y, Fukuda M
GLYCOBIOLOGY, 15(10), 1016-1024, 2005

MCI-186 (edaravone), a free radical scavenger, attenuates hepatic warm ischemia-reperfusion injury in rats
Suzuki F, Hashikura Y, Ise H, Ishida A, Nakayama J, Takahashi M,Miyagawa S, Ikeda U
Transpl Int, 18(7), 844-853, 2005

Crucial roles of mesodermal cell lineages in a murine embryonic stem cell-derived in vitro liver organogenesis system
Ogawa S, Tagawa Y, Kamiyoshi A, SuzukiA, Nakayama J, Hashikura Y, Miyagawa S
Stem Cells, 23(7), 903-913, 2005

Arachidonic acid-induced COX-1 and COX-2-mediated vasodilation in rat gingival arterioles in vivo
Nakatsuka A, Mizuno R, Ono N, Nakayama J, Ohhashi T
Jpn J Physiol, 55(5), 293-302, 2005

Malignant myoepithelioma (myoepithelial carcinoma) of soft tissue
Harada O, Ota H, Nakayama J
Pathol Int, 55(8), 510-513, 2005

Expression of Fas ligand by hepatic macrophages in patients with fulminant hepatic failure
Mita A, Hashikura Y, Tagawa Y-i, Nakayama J, Kawakubo M, Miyagawa S
Am J Gastroenterol, 100(11), 2551-2559, 2005

A subtype of human gastric mucins expressing alpha1,4-GlcNAc-capped O-glycans functions as a natural antibiotic against Helicobacter pylori infection
Nakayama, J; Kawakubo, M; Ito, Y; Kobayashi, M; Fukuda, MN; Fukuda, M; Katsuyama, T
GLYCOBIOLOGY, 14(11), 1073-1073, 2004

Degenerative thalamic hamartoma: CT and MR imaging features
Kaneko T, Kawakami R, Fujinaga Y, Oguchi K, Nakayama J, Hongo K, Kadoya M
Am J Neuroradiol, 25(5), 766-768, 2004

Gross total surgical removal of malignant glioma from the medulla oblongata: report of two adult cases with reference to surgicalanatomy
Kyoshima K, Sakai K, Goto T, Tanabe A, Sato A, Nagashima H, Nakayama J
J Clin Neurosci, 11(1), 75-80, 2004

Polysialic acid and HNK-1 are expressed in the adult rat vestibular endorgans
Isawa M, Takumi Y, Hashimoto S, Nakayama J, Usami S
NEUROREPORT, 15(10), 1575-1578, 2004

Pulmonary lymphoepithelioma-like carcinoma: predominant infiltration of tumor-associated cytotoxic Tlymphocytes might represent the enhanced tumor immunity
Kobayashi M, Ito M, Sano K, Honda T, Nakayama J
Intern Med, 43(4), 323-326, 2004

Symmetric Dumbbell Ganglioneuromas of Bilateral C2 and C3 Roots with Intradural Extension Associated with Von Recklinghausen's Disease:Case Report
Kyoshima K, Sakai K, Kanaji M, Oikawa S, Kobayashi S, Sato A, Nakayama J
Surg Neurol, 61(5), 468-473, 2004

Functional correlation of trophinin expression with the malignancy of testicular germ cell tumor
Hatakeyama S, Ohyama C, Minagawa S, Inoue T, Kakinuma H, Kyan A, Arai Y, Suga T, Nakayama J, Kato T, Habuchi T, Fukuda MN
Cancer Res, 64(12), 4257-4262, 2004

Inducible expression of p57KIP2 inhibits glioma cell motility and invasion
Sakai K, Peraud A, Mainprize T,Nakayama J, Tsugu A, Hongo K, Kobayashi S, Rutka JT T, Rutka
J Neurooncol, 68(3), 217-223, 2004

Induction of peripheral lymph node addressin in human gastric mucosa infected by Helicobacter pylori
Kobayashi M, Mitoma J, Nakamura N, Katsuyama T, Nakayama J, Fukuda M
Proc Natl Acad Sci USA, 101(51), 17807-17812, 2004

Core 2 branching β1,6-N-acetylglucosaminyltransferase and heig endothelial venule-restricted sulfotransferase collaboratively control lymphocyte homing
Hiraoka N, Kawashima H, Petryniak B, Nakayama J, Mitoma J, Marth JD, Lowe JB, Fukuda M
J Biol Chem, 279(4), 3058-3067, 2004

Natural antibiotic function of a human gastric mucin against Helicobacter pylori infection
Kawakubo M, Ito Y, Okimura Y, Kobayashi M, Sakura K, Kasama S, Fukuda MN, Fukuda M, Katsuyama T, Nakayama J
science, 305(5686), 1003-1006, 2004

Molecular cloning and expression of HRLRRP, a novel heart-restricted leucine-rich repeat protein
Nakane T, Satoh T, Inada Y, Nakayama J, Itoh E Chiba S
Biochem Biophys Res Commun, 314(4), 1086-1092, 2004

Purification and measurement of HDL3-binding proteins in human peripheral blood mononuclear cells
Hidaka, H; Tozuka, M; Yamauchi, K; Ohta, H; Nakayama, J; Katsuyama, T
Ann Clin Lab Sci, 33(3), 271-278, 2003

Differential expression of ribosomal proteins in human normal and neoplastic colorectum
Kasai, H; Nadano, D; Hidaka, E; Higuchi, K; Kawakubo, M; Sato, TA; Nakayama, J
J Histochem Cytochem, 51(5), 567-573, 2003

Immunohistochemical localization of hepatocyte growth factor activator (HGFA) in developing mouse liver tissues: Heterogeneous distribution of HGFA protein
Iida, I; Johkura, K; Teng, RF; Kubota, S; Cui, L; Zhao, X; Ogiwara, N; Okouchi, Y; Asanuma, K; Nakayama, J; Sasaki, K
J Histochem Cytochem, 51(9), 1139-1149, 2003

Expression of gastric gland mucous cell-type mucin in normal and neoplastic human tissues
Nakajima, K; Ota, H; Zhang, MX; Sano, K; Honda, T; Ishii, K; Nakayama, J
J Histochem Cytochem, 51(12), 1689-1698, 2003

Helicobacter pylori infection up-regulates gland mucous cell-type mucins in gastric pyloric mucosa
Matsuzawa M, Ota H, Hiyama M, Zhang MX, Sano K, Honda T, Ueno I, Akamatsu T, Nakayama J
HELICOBACTER, 8(6), 594-600, 2003

Mouse model of N-acetylgalactosamine-6-sulfate sulfatase deficiency (Galns(-/-)) produced by targeted disruption of the gene defective in Morquio A disease
Tomatsu, S; Orii, KO; Vogler, C; Nakayama,J; Levy, B; Grubb, JH; Gutierrez, MA; Shim, S; Yamaguchi, S; Nishioka, T; Montano, AM; Noguchi, A; Orii, T; Kondo, N; Sly, WS
Hum Mol Genet, 12(24), 3349-3358, 2003

Temporal and spatial expression profiles of BMP receptors and Noggin during BMP-2-induced ectopic bone formation
Nakamura, Y; Wakitani, S; Nakayama, J; Wakabayashi, S; Horiuchi, H; Takaoka, K
J Bone Miner Res, 18(10), 1854-1862, 2003

Life-threatening veno-occlusive disease after living-related liver transplantation
Nakazawa, Y; Chisuwa, H; Mita, A; Ikegami,T; Hashikura, Y; Terada, M; Nakayama, J; Kawasaki, S
TRANSPLANTATION, 75(5), 727-730, 2003

Usefulness of the real-time reverse transcription-polymerase chain reaction assay targeted to alpha1,4-N-acetylglucosaminyltransferase for the detection of gastric cancer
Shimizu F, Nakayama J, Ishizone S, Zhang M X, Kawakubo M, Ota H, Sugiyama A, Kawasaki S, Fukuda M, Katsuyama T
Lab Invest, 83(2), 187-197, 2003

Implantation-dependent expression of trophinin by maternal Fallopian tube epithelia during tubal pregnancies: Possible role of human chorionic gonadotrophin on ectopic pregnancy
Nakayama J, Aoki D, Suga T, Akama T O, Ishizone S, Yamaguchi H, Imakawa K, Nadano D, Fazleabas A T, Katsuyama T, Nozawa S, Fukuda M N
Am J Pathol, 163(6), 2211-2219, 2003

Polysialic acid and mucin type O-glycans on the neural cell adhesion molecule differentially regulate myoblast fusion
Suzuki, M; Angata, K; Nakayama, J; Fukuda, M
J Biol Chem, 278(49), 49459-49468, 2003

Usefulness of albumin scintigraphyin a pediatric liver transplant recipient with gastrointestinal posttransplant lymphoproliferative disorder
Mita A, Hashikura Y, Momose M, Nakayama J, Sasaki E, Ikegami T, Nakazawa Y, Chisuwa H, Terada M, Kawasaki S
Liver Transpl, 8, 568-569, 2002

a4-N-acetylglucosaminyltra- nsferase
Nakayama J
Taniguchi N, Honke K, Fukuda M eds: Handbook of Glycosyltransferases and Related Genes, 151-157, 2002

a1,4-N-acetylglucosaminyltransferase and gastric cancer. Barrett JC, Imai K, Kakizoe T, Shively J E, and Yamaguchi K eds: Basic and Clinical Research on Tumor Markers
Nakayama J, Shimizu F, Zhang MX, Fukuda M, Katsuyama T
Extended Abstracts for the 32nd International Symposium of the Princess Takamatsu Cancer Research Fund, 61-65, 2002

Sialyl Lewis X-dependent lung colonization of B16 melanoma cells through a selectin-like endothelial receptor distinct from E- or P-selectin
Zhang J, Nakayama J, Ohyama C, Suzuki M, Suzuki A, Fukuda M, Fukuda M N
Cancer Res, 62(15), 4194-4198, 2002

Malignant astrocytoma of the conus medullaris treated by spinal cordectomy
Kyoshima K,Ito K, Tanabe A, Iwashita T, Goto T, Sato A, Nakayama J
J Clin Neurosci, 9(2), 211-216, 2002

Evaluation of 5-S-cysteinyidopa as a markerof melanoma progression: 10 years' experience
Wakamatsu, K; Kageshita, T; Furue, M; Hatta, N; Kiyohara, Y; Nakayama, J; Ono, T; Saida, T; Takata, M; Tsuchida, T; Uhara, H; Yamamoto, A; Yamazaki, N; Naito, A; Ito, S
MELANOMA RESEARCH, 12(3), 245-253, 2002

Anti-neovascular therapy using novel peptides homing to angiogenic vessels
Oku N, Asai T, Watanabe K, Kuromi K, Nagatsuka M, Kurohane K, Kikkawa H, Ogino K, Tanaka M, Ishikawa D, Tsukada H, Momose M, Nakayama J, Taki T
Oncogene, 21(17), 2662-2669, 2002

Association of GM4 ganglioside with the membrane surrounding lipid droplets in shark liver
Li Y-T, Sugiyama E, Ariga T, Nakayama J, Hayama M, Hama Y, Nakagawa H, Tai T, Maskos K, Li S-C, Kasama T
J Lipid Res, 43(7), 1019-1025, 2002

Significant differences between mouse and human trophinins are revealed by their expression patterns and targeted disruption of mouse trophinin gene
Nadano D, Sugihara K, Paria BC, Saburi S, Copeland NG, Gilbert DJ, Jenkins NA, Nakayama J, Fukuda MN
Biol Reprod, 66(2), 313-321, 2002

Human tastin, a proline-rich cytoplasmic protein, associates with the microtubular cytoskeleton
Nadano D, Nakayama J, Matsuzawa S, Sato T, Matsuda T, Fukuda MN
Biochem J, 364, 669-677, 2002

Immunohistochemical demonstration od alpha,4-N-acetylglucosaminyltransferase that forms GlcNAc alpha 1,4Gal beta residues in human gastrointestinal mucosa
Zhang, MX; Nakayama, J; Hidaka, E; Kubota, S; Yan, J; Ota, H; Fukuda, M
J Histochem Cytochem, 49(5), 587-596, 2001

Extrahepatic expression of apolipoprotein A-II in mouse tissues: Possible contribution to mouse senile amyloidosis
Fu, L; Matsuyama, I; Chiba, T; Xing, YM; Korenaga, T; Guo, ZJ; Fu, XY; Nakayama, J; Mori, M; Higuchi, K
J Histochem Cytochem, 49(6), 739-747, 2001

Expression of apoptosis-associated speck-like protein containing a caspase recruitment domain, a pyrin N-terminal homology domain-containing protein, in normal human tissues
Masumoto, J; Taniguchi, S; Nakayama, J; Shiohara, M; Hidaka, E; Katsuyama, T; Murase, S; Sagara, J
J Histochem Cytochem, 49(10), 1269-1275, 2001

Prognostic significance of polysialic acid expression in resected non-small cell lung cancer
Tanaka, F; Otake, Y; Nakagawa, T; Kawano, Y; Miyahara, R; Li, M; Yanagihara, K; Inui, K; Oyanagi, H; Yamada, T; Nakayama, J; Fujimoto, I; Ikenaka, K; Wada, H
Cancer Res, 61(4), 1666-1670, 2001

Clinicopathological significance of core 2 beta1,6-N-acetylglucosaminyltransferase messenger RNA expressed in the pulmonary adenocarcinoma determined by in situ hybridization
Machida E, Nakayama J, Amano J, Fukuda M
Cancer Res, 61(5), 2226-2231, 2001

Cell lineage specificity of newly raised monoclonal antibodies against gastric mucins in normal, metaplastic, and neoplastic humantissues and their application to pathology diagnosis
Ota, H; Hayama, M; Nakayama, J; Hidaka, H; Honda, T; Ishii, K; Fukushima, M; Uehara, T; Kurihara, M; Ishihara, K; Hotta, K; Katsuyama, T
Am J Clin Pathol, 115(1), 69-79, 2001

Molecular cloning and characterization of a human beta-Gal-3'-sulfotransferase that acts on both type 1 and type 2 (Galbeta1-3/1-4GlcNAc-R) oligosaccharides
Honke K, Tsuda M, KoyotaS, Wada Y, Iida-Tanaka N, Ishizuka I, Nakayama J, Taniguchi N
J Biol Chem, 276(1), 267-274, 2001

Helicobacter pylori and two ultrastructurally distinct layers of gastric mucous cell mucins in the surfacemucous gel layer
Hidaka, E; Ota, H; Hidaka, H; Hayama, M; Matsuzawa, K; Akamatsu, T; Nakayama, J; Katsuyama, T
Gut, 49(4), 474-480, 2001

Fatal hemophagocytic syndrome after living-related liver transplantation - A report of two cases
Chisuwa, H; Hashikura, Y; Nakazawa, Y; Kamijo, T; Nakazawa, K; Nakayama, J; Oh-ishi, T; Ikegami, T; Terada, M; Kawasaki, S
TRANSPLANTATION, 72(11), 1843-1846, 2001

Effect of polysialic acid on the tumor xenografts implanted into nude mice
Jimbo, T; Nakayama, J; Akahane, K; Fukuda, M
Int J Cancer, 94(2), 192-199, 2001

Novel sulfated lymphocyte homing receptors and their control by a core1 extension beta1,3-N-acetylglucosaminyltransferase
Yeh J-C, Hiraoka N, Petryniak B, Nakayama J, Ellise L G, Rabuka D, Hindsgaul O, Marth J, Lowe J B, Fukuda M
Cell, 105(7), 957-969, 2001

Human corneal GlcNAc 6-O-sulfotransferase and mouse intestinal GlcNAc 6-O-sulfotransferase both produce keratan sulfate
Akama, TO; Nakayama, J; Nishida, K; Hiraoka, N; Suzuki, M; McAuliffe, J; Hindsgaul, O; Fukuda, M; Fukuda, MN
J Biol Chem, 276(19), 16271-16278, 2001

A novel endo-beta-galactosidase from Clostridium perfringens that liberates the disaccharide GlcNAc alpha 1,4Gal from glycans specifically expressed in the gastric gland mucous cell-type mucin
Ashida H, Anderson K, Nakayama J, Maskos K, Chou C-W, Cole R B, Li S-C, Li Y-T
J Biol Chem, 276(30), 28226-28232, 2001

Macular corneal dystrophy type I and type II are caused by distinct mutations in a new sulphotransferase gene
Akama T O, Nishida K, Nakayama J, Watanabe H, Ozaki K, Nakamura T, Dota A, Kawasaki S, Inoue Y, Maeda N, Yamamoto S, Fujiwara T, Thonar E J-M A, Shimomura Y, Kinoshita S, Tanigami A, Fukuda M N
Nat Genet, 26(2), 237-241, 2000

Expression of polysialic acid and STX, a human polysialyltransferase, is correlated with tumor progression in non small cell lung cancer
Tanaka, F; Otake, Y;Nakagawa, T; Kawano, Y; Miyahara, R; Li, M; Yanagihara, K; Nakayama, J; Fujimoto, I; Ikenaka, K; Wada, H
Cancer Res, 60(11), 3072-3080, 2000

Proliferation-associated expression of the MEN1 gene as revealed by in situ hybridization: Possible role of the menin as a negative regulator of cell proliferation under DNA damage
Ikeo, Y; Sakurai, A; Suzuki, R; Zhang, MX; Koizumi, S; Takeuchi, Y; Yumita, W; Nakayama, J; Hashizume, K
Lab Invest, 80(6), 797-804, 2000

Recent progress in paradoxical concanavalin A staining
Nakayama, J; Katsuyama, T; Fukuda, M
Acta Histochem Cytochem, 33(3), 153-157, 2000

Primary cardiac malignant fibrous histiocytoma in the right ventricular infundibulum treated with a cavo-pulmonary shunt and coronary embolization
Owa, M; Higashikata, T; Shimada, H; Kitahara, H; Asano, M; Nakayama, J; Hikita, H; Koyama, J; Sakurai, S; Ikeda, S
Jpn Circ J, 64(12), 982-984, 2000

Coexistence of gland mucous cell-type mucin and lysozyme in gastric gland mucous cells
Hidaka, E; Ota, H; Katsuyama, T; Nakayama, J; Momose, M; Hidaka, H; Ishii, K; Murata, F; Tsuyama, S; Kurihara, M; Ishihara, K; Hotta, K
Histochem Cell Biol, 113(2), 91-98, 2000

The identification of specific high density lipoprotein(3) binding sites on human blood monocytes using fluorescence-labeled ligand
Hidaka, H; Hidaka, E; Tozuka, M; Nakayama, J; Katsuyama, T; Fidge, N
J Lipid Res, 40(6), 1131-1139, 1999

Expression of N-acetyllactosamine and beta 1,4-galactosyltransferase (beta 4GalT-I) during adenoma-carcinoma sequence in the human colorectum
Ichikawa, T; Nakayama, J; Sakura, N; Hashimoto, T; Fukuda, M; Fukuda,MN; Taki, T
J Histochem Cytochem, 47(12), 1593-1601, 1999

Expression cloning of a human alpha1,4-N-acetylglucosaminyltransferase that forms GlcNAc alpha1-4Galbeta-R, a glycan specifically expressed in the gastric gland mucous cell-type mucin
Nakayama J, Yeh J-C, Misra A K, Ito S, Katsuyama T, Fukuda M
Proc Natl Acad Sci USA, 96(16), 8991-8996, 1999

A novel, high endothelial venule-specific sulfotransferase expresses 6-sulfo sialyl Lewis x, an L-selectin ligand displayed by CD34
Hiraoka N, Petryniak B, Nakayama J, Tsuboi S, Suzuki M, Yeh J-C, Izawa D, Tanaka T, Miyasaka M, Lowe J B, Fukuda M
Immunity, 11(1), 79-89, 1999

Brunner's gland metaplasia of residual jejunum developed long after wide resection of the small intestine
Nakamura, T; Shimada, M; Nakayama, J; Katsuyama, T
Pathol Int, 49(10), 918-920, 1999

Detection of GB virus-C hepatitis G virus genome in peripheral blood mononuclear cells and liver tissue
Kobayashi, M; Tanaka, E; Nakayama, J; Furuwatari, C; Katsuyama, T; Kawasaki, S; Kiyosawa, K
J Med Virol, 57(2), 114-121, 1999

Expression of trophinin, tastin, and bystin by trophoblast and endometrial cells in human placenta
Suzuki, N; Nakayama, J; Shih, IM; Aoki, D; Nozawa, S; Fukuda, MN
Biol Reprod, 60(3), 621-627, 1999

Developmental regulation of polysialic acid synthesis in mouse directed by two polysialyltransferases,PST and STX
Ong, E; Nakayama, J; Angata, K; Reyes, L; Katsuyama, T; Arai, Y; Fukuda, M
GLYCOBIOLOGY, 8(4), 415-424, 1998

Polysialic acid, a unique glycan that is developmentally regulated by two polysialyltransferases, PST and STX, in the central nervous system: From biosynthesis to function
Nakayama, J; Angata, K; Ong, E; Katsuyama, T; Fukuda, M
Pathol Int, 48(9), 665-677, 1998

New monoclonal antibodies against gastric gland mucous cell-type mucins: a comparative immunohistochemical study
Ota, H; Nakayama, J; Momose, M; Kurihara, M; Ishihara, K; Hotta, K; Katsuyama, T
Histochem Cell Biol, 110(2), 113-119, 1998

Helicobacter pylori infection produces reversible glycosylation changes to gastric mucins
Ota, H; Nakayama, J; Momose, M; Hayama, M; Akamatsu, T; Katsuyama, T; Graham, DY;Genta, RM
VIRCHOWS ARCHIV, 433(5), 419-426, 1998

Expression cloning and characterization of a cDNA encoding a novel membrane protein required for the formation of O-acetylated ganglioside: A putative acetyl-CoA transporter
Kanamori A, Nakayama J, Fukuda MN, Stallcup W B, Sasaki K, Fukuda M, Hirabayashi Y
Proc Natl Acad Sci USA, 94, 2897-2902, 1997

Enhanced expression of prostate-specific membrane antigen gene in prostate cancer as revealed by in situ hybridization
Kawakami, M; Nakayama, J
Cancer Res, 57(12), 2321-2324, 1997

Carcinoma-associated expression of core 2 beta-1,6-N-acetylglucosaminyltransferase gene in human colorectal cancer: Role of O-glycans in tumor progression
Shimodaira, K; Nakayama, J; Nakamura, N; Hasebe, O; Katsuyama, T; Fukuda, M
Cancer Res, 57(23), 5201-5206, 1997

Human STX polysialyltransferase forms the embryonic form of the neural cell adhesion molecule - Tissue-specific expression, neurite outgrowth, and chromosomal localization in comparison with another polysialyltransferase, PST
Angata, K; Nakayama, J; Fredette, B; Chong, K; Ranscht, B; Fukuda, M
J Biol Chem, 272(11), 7182-7190, 1997

Histone H3 messenger RNA in situhybridization for identifying proliferating cells in formalin-fixed rat gastric mucosa
Maeyama, H; Furuwatari, C; Ota, H; Akamatsu, T; Nakayama, J; Katsuyama, T
Histochem J, 29(11-12), 867-873, 1997

Expression cloning of glycosyltransferases
Fukuda M, Bierhuizen MFA, Nakayama J
GLYCOBIOLOGY, 6, 683-689, 1996

A human polysialyltransferase directs in vitro synthesis of polysialic acid
Nakayama J, Fukuda M
J Biol Chem, 271, 1829-1832, 1996

Expression cloning of a human GT3 synthase. GD3 and GT3 are synthesized by a single enzyme
Nakayama J, Fukuda MN, Hirabayashi Y, Kanamori A, Sasaki K, Nishi T, Fukuda M
J Biol Chem, 271, 3684-3691, 1996

Trophinin and tastin, a novel cell adhesion molecule complex with potential involvement in embryo implantation
Fukuda MN, Sato T, Nakayama J, Klier G, Mikami M, Aoki D, Nozawa S
Genes Dev, 9, 1199-1210, 1995

Expression cloning of a human polysialyltransferase that forms the polysialylated neural cell adhesion molecule present in embryonic brain
Nakayama J, Fukuda MN, Fredette B, Ranscht B, Fukuda M
Proc Natl Acad Sci USA, 92, 7031-7035, 1995

Frequently relapsing minimal change nephrotic syndrome with natural killer cell deficiency prior to the overt relapse of Hodgkin’s disease
Mori T, Yabuhara A, Nakayama J, Kitahara M, Washizawa K, Kasai S, Komiyama A
Pediatr Nephorol, 9(5), 619-620, 1995

Application of mucin histochemistry for pathological diagnosis. - Expession of gastric phenoypes in metaplastic and neoplastic lesions and its relation to the organoid differentiation -
Ota H, Katsuyama T, Akamatsu T, Fujimori Y, Matsuzawa K, Ishii K, Honda T, Nakayama J, Furihata K, Ono K, Maeda K
Acta Histochem Cytochem, 28(1), 43-53, 1995

Proposal for an aeroschema (modified Aerokey II) for the identification of cllinical Aeromonas species
Furuwatari C, Kawakami Y, Akahane T, Hidaka E, Okimura Y, Nakayama J, Furihata K, Katsuyama T
Med Sci Res, 22(9), 617-619, 1994

Expression of Forssman antigen in human large intestine
Ono K, Hattori H, Uemura K, Nakayama J, Ota H, Katsuyama T
J Histochem Cytochem, 42(5), 659-665, 1994

Liver injury following normothermic ishemia in steatotic rat liver
Hui A, Kawasaki S, Makuuchi M, Nakayama J, Ikegami T, Miyagawa S
Hepatology, 20(5), 1287-1293, 1994

Monoclonal antibody E6G6 recognizes glycolipids as a differentiation antigen in shope carcinoma cells
Kyogashima M, Inoue M, Isono T, Nakayama J, Seto A
Cancer Lett, 81(2), 221-228, 1994

Organizing differentiation of tumorcells of villous adenomas of the large intestine
Ota H, Nakayama J, Fujimori Y, Furihata K, Katsuyama T, Moriyama S, Hata S, Ono K
Acta Histochem Cytochem, 26(2), 117-125, 1993

Polysialosyl glycoconjugates defined by monoclonal antibody M6704 are expressed in human gliomas and embryonic neurons
Nakayama J, Katsuyama T, Sugiyama E, Hirabayashi Y
J Histochem Cytochem, 41(10), 1563-1572, 1993

Primary hyperparathyroidism masquerading as immobilization hypercalcemia -report of an illustrative case
Monno S, Yokozawa T, Mizushima Y, Nakayama J,Ohgaku S, Kato H, Takasu N, Kobayashi M
Endocrine J, 40(1), 35-39, 1993

Establishment of Epstein-Barr virus-associated lymphoma cell line SUBL with t(2;3)(p11;q27) from a liver transplant patient
Yoshizawa K, Kiyosawa K, Yamada S, Furuta K, Yabu K, Kitano K, Akamatsu T, Nakayama J, Katsuyama T, Matsunami H, Kawasaki S, Makuuchi M, Nanba K, Furuta S
Cancer Genet Cytogenet, 71(2), 155-163, 1993

The antitumor activity and immunosuppressive effects of 5-fluorouracil suppositories in rectal cancer patients
Adachi W, Sugenoya A, Horigome N, Takahashi C, Iida F, Nakayama J
Surg Today, 22(3), 221-225, 1992

Histochemical demonstration of gastrointestinal mucins in ovarian mucinous cystadenoma
Shiozawa T, Tsukahara Y, Ishii K, Ota H, Nakayama J, Katsuyama T
Acta Pathol Jpn, 42(2), 104-110, 1992

Distribution of retinol-binding protein in the human digestive tract
Kameko M, Ota H, Ishii K, Nakayama J, Katsuyama T, Kanai M, Tsutsumi Y
Virchows Arch B, 61(5), 315-322, 1992

Aberrant expression of blood group H-antigen in shope carcinoma cells
Kyogashima M, Inoue M, Nakayama J, Seto A
Cancer Lett, 66(3), 175-181, 1992

Immunohistochemical demonstration of glycoconjugates bearing the type 2 chain-backbone structurein human fetal, normal and neoplastic gastrointestinal tract
Nakayama J, Ota H, Katsuyama T, Kanai M, Taki T, Hirabayashi Y, Suzuki Y
Histochemistry, 97(4), 303-310, 1992

Lectin histochemistry of the normal human endometrium and endometrial adenocarcinoma
Shiozawa T, Tsukahara Y, Nakayama J, Katsuyama T
Acta Histochem Cytochem, 24(2), 233-240, 1991

Immunohistochemical localization of blood group substances in normal and neoplastic endometrial tissues - with special reference to type 1 core chain expression
Shiozawa T, Tsukahara Y, Nakayama J, Ishii K, Katsuyama T
Gynecol Obstet Invest, 32(3), 185-188, 1991

Immunohistochemical reactivity of antikeratan sulfate monoclonal antibody 5D4 to various conditions of human endometrial tissues and its application as a useful marker for identifying endometrial epithelia
Shiozawa T, Tsukahara Y, Nakayama J, Ishii K, Katsuyama T
Gynecol Obstet Invest, 32(4), 239-242, 1991

A new monoclonal antibody directed to sialyl-alpha2-3 lactoneotetraosylceramide and its application for detection of human gastrointestinal neoplasms
Suzuki Y, Nishi H, Hidari K, Hirabayashi Y, Matsumoto M, Kobayashi T, Watari S, Yasuda T, Nakayama J, Maeda H, Katsuyama T, Kanai M, Kiso M, Hasegawa A
J Biochem (Tokyo), 109(2), 354-360, 1991

A dual staining method for identifying mucins of different gastric epithelial mucous cells
Ota H, Katsuyama T, Ishii K, Nakayama J, Shiozawa T, Tsukahara Y
Histochem J, 23(1), 22-28, 1991

Adenocarcinoma of the cervical oesophagus arising from ectopic gastric mucosa - the histochemical determination of its origin
Ishii K, Ota H, Nakayama J, Katsuyama T, Matsuzawa K, Honda T, Akamtsu T
Virchows Arch A, 419(2), 159-164, 1991

Accumulation of gangliosides with N-acetylneuraminosyl(α2-6)lactosamine structure in primary human hepatoma
Taki T, Yamamoto K, Takamatsu M, Ishii K, Myoga A, Sekiguchi K, Ikeda I, Kurata K, Nakayama J, Handa S, Matsumoto M
Cancer Res, 50(4), 1284-1290, 1990

Griffonia simplicifolia agglutinin-2-binding glycoprotein as a novel carbohydrate antigen of human colonic carcinoma
Nakayama J, Okano A, Maeda H, Miyachi M, Ota H, Katsuyama T, Kanai M
Jpn J Cancer Res, 81(4), 388-395, 1990

Limitation in defining ablation line by maginified endoscopic imaging for endoscopic submucosal resection of gastric adenocarcinoma of fundic gland type as revealed by 3D redonstruction images of gastric tissue specimens.
Yamada S, Matsuura H, Nakayama J
J Can Assoc Gastroenterol, 1, 137 - 138, 2018, Refereed

Shinshu Brain Resource Net
Oyanagi K, Yamada M, Hineno A, Yahikozawa H, Ushiyama M, Miki J, Kanno H, Nakayama J, Makishita H, Inoue K, Ohara S, Hayashida K, Kayanuma K, Yamamoto K, Yasude T, Hashimoto T, Yoshida K, Ikeda S-i
Neuropathology, 36, 600 - 601, 2016, Refereed

Interleukin-1β suppression in Blau syndrome: comment on the article by Martin et al.
Masumoto J, Yamazaki T, Ohta K, Nakayama J, Agematsu K
Arthritis Rheum, 60, 2544 - 2545, 2009, Refereed

Sulfation patterns of keratan sulphate in different macular corneal dystrophy immunophenotypes using three different probes
Saito T, Nishida K, Nakayama J, Akama TO, Fukuda MN, Watanabe K, Quantock AJ, Maeda N, Watanabe H, Tano Y
Br J Ophthalmol, 92, 1434 - 1436, 2008, Refereed

Malignant granular cell tumor of the esophagus
Yoshizawa A, Ota H, Sakaguchi N, Kanai S, Nakayama J, Matsuzawa K, Tsuzuki S, Takada R, Miyazawa F, Kasahara H, Katsuyama T
Virchows Arch, 444, 304 - 306, 2004, Refereed

Association of smoking with apoptosis-regulated proteins (Bcl-2, Bax and p53) in resected non-small-cell lung cancers
Hanaoka, T; Nakayama, J; Mukai, J; Irie, S; Yamanda, T; Sato, TA
Int J Cancer, 91, 267 - 269, 2001, Refereed

Relation of H pylori to gastric mucins andgastric surface mucous gel layer
Ota, H; Nakayama, J; Shimizu, T; Nakayama, J; Graham, DY; Katsuyama, T
Gut, 48, 869 - 870, 2001, Refereed

Gastric gland mucous cells circulate in peripheral blood after endoscopic biopsy of the gastric mucosa
Shimizu, F; Nakayama, J; Sugiyama, A; Kawasaki, S; Katsuyama, T
Am J Gastroenterol, 10, 3017 - 3018, 2000, Refereed

Glycoscience: Basic Science to Applications – Insights from the Japan Consortium for Glycobiology and Glycotechnology
Nakayama J, Contributor, Gastric cancer
Springer-Nature Singapore, 303-304 2019

Glycosignals in Cancer: Mechanisms of Malignant Phenotypes
Nakayama J, Contributor, Function of unique O-glycan structures in protecting gastric mucosa against Helicobacter pylori infection and gastric cancer development
Springer Japan, 111-124 2016

Handbook of Glycosyltransferases and Related Genes, 2nd ed.
Nakayama J, Contributor, Alpha-1,4-N-acetylglucosaminyltransferase (A4GNT)
Springer Japan, 379-391 2014

Glycoscience: Biology and Medicine
Kawakubo M, Ito Y, Fukuda M, Nakayama J, Contributor, Helicobacter pylori
Springer Japan, 723-729 2014

Taniguchi N, Honke K, Fukuda M eds: Handbook of Glycosyltransferases and Related Genes
Nakayama J, Angata K, Suzuki M, Fukuda M, Contributor, ST8Sia-IV (PST-1)
340-346 2002

Preventive role of the gland mucin-specific αGlcNAc in gastric cancer development
Nakayama J
The 12th China-Japan Joint Seminar on Histochemictry and Cytochemistry, 2017

Dual roles of gastric gland mucin-specific O-glycan on prevention of gastric cancer
Nakayama J
14th International Congress of Histochemistry and Cytochemistry., 2012

Preventive roles of gastric gland mucin in pathogenesis of gastric cancer
Nakayama J
The 43rd International Symposium of The Princess Takamatsu Cancer Research Fund, 2012

Interaction of Helicobacter pylori and O-glycans in stomach
Nakayama J
Glycobiology Japan-Netherland Joint Seminar 2011, 2011

A subtype of human gastric mucins expressing alpha1,4-GlcNAc-capped O-glycans functions as a natural antibiotic against Helicobacter pylori infection
Nakayama J, Kawakubo M, Ito Y, Kobayashi M, Fukuda NM, Fukuda M, Katsuyama T
US/Japan Glyco 2004, 2004

Detection of circulating gastric cancer cells using real-time RT-PCR targeted α1,4-N-Acetylglucosaminyltransferase messenger RNA
Nakayama J, Shimizu F, Zhang MX, Fukuda M, Katsuyama T
The 18th International Congress of Clinical Chemistry and Laboratory Medicine, 2002

α1,4-N-Acetylglucosaminyltransferase and gastric cancer
Nakayama J, Shimizu F, Zhang MX, Fukuda M, Katsuyama T
The 32nd International Symposium of the Princess Takamatsu Cancer Research Fund, 2001

Expression cloning of a human α-1,4-N-acetylglucosaminyltransferase that forms GlcNAcα1-4Galβ-R, a unique glycan for the gastric gland mucous cell-type mucin
Nakayama J, Yeh JC, Misra A, Ito S, Katsuyama T, Fukuda M
XVth International Symposium on Glycoconjugates, 1999

Developmentally regulated-expression of polysialic acid in nervous system directed by two polysialyltransferases, PST and STX
Nakayama J, Angata K, Ong E, Onishi N, Katsuyama T, Arai Y, Fukuda M
10th International Congress of Histochemistry and Cytochemistry, 1996

A newly cloned polysialyltransferase forms the embryonic form of N-CAM that facilitates neurite outgrowth
Nakayama J, Fukuda MN, Fredette B, Ranscht B, Fukuda M
XIIIth International Symposium on Glycoconjugates, 1995

American Association for Cancer Research

The Histochemical Society

The Japanese Society of Pathology

Japanese Cancer Association

The Japanese society of clinical cytology

Japn Society of Histochemistry and Cytochemistry

Japan Society for Moleculer Tumor Marker Reseach

Japanese Society for Gastroenterological Carcinogenesis

Japanese Society of Laboratory Medicine

The Japanese Society of Neurology

The Japanese Society of Carbohydrate Research

The Japanese Society of Internal Medicine

The Japanese Society of Neuropathology

Japanese Society for Pediatric Pathology

The Japanese Association for Metastasis Research

The Shinshu Medical Society

Regulation of gastric cancer development by gland mucin-specific glycans
Grant-in-Aid for Scientific Research
2000

Expression of carbohydrtes and its clinicopathological significance of in tumor
Grant-in-Aid for Scientific Research
1995

Application of histochemistry for pathology
1995

Others
J Histochem Cytochem

Others
Acta Histochem Cytochem